Company: SCLXW
Filing Date: 2025-05-15
Form Type: 424B3
Source: 0000950170-25-071904
Chunk: 64

Company: Scilex Holding Co
Filing Date: 2025-05-15
Form: 424B3
Chunk 64
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 were immaterial for the periods presented. Supplemental quantitative information related to leases includes the following:

| Cash paid for amounts included in the measurement of lease liabilities: |     | Three Months Ended March 31, 
 2025                         |      |   |     | 2024 |      |   |
|:------------------------------------------------------------------------|:----|:-----------------------------|-----:|:--|:----|:-----|-----:|:--|
| Operating cash flows from operating leases (in thousands)               |     | $                            | (227 | ) |     | $    | (277 | ) |
| Weighted average remaining lease term in years — operating leases       |     |                              |  2.5 |   |     |      |  3.4 |   |
| Weighted average discount rate — operating leases                       |     |                              | 11.0 | % |     |      | 11.0 | % |

Approximate future minimum lease payments under operating leases were as follows (in thousands):

|                                         |     | Amount |       |   |
|:----------------------------------------|:----|:-------|------:|:--|
| 2025 (Remainder of 2025)                |     | $      |   689 |   |
| 2026                                    |     |        |   944 |   |
| 2027                                    |     |        |   724 |   |
| Total lease payments                    |     |        | 2,357 |   |
| Less imputed interest                   |     |        |  (290 | ) |
| Total lease liabilities                 |     |        | 2,067 |   |
| Less current portion of lease liability |     |        |   740 |   |
| Lease liability, net of current portion |     | $      | 1,327 |   |

<div align='center'>33</div>

12. Net Loss Per Share The following table sets forth the reconciliation of basic and diluted loss per share for the three months ended March 31, 2025 and 2023 (in thousands except per share data):

|                                                                              |     | Three Months Ended March 31, |    2025 |   |     |   |    2024 |   |
|:-----------------------------------------------------------------------------|:----|:-----------------------------|--------:|:--|:----|:--|--------:|:--|
| Net loss                                                                     |     | $                            |