Company: NDRA
Filing Date: 2025-10-30
Form Type: 424B5
Source: 0001213900-25-103705
Chunk: 61

Company: ENDRA Life Sciences Inc.
Filing Date: 2025-10-30
Form: 424B5
Chunk 61
---
 any of the provisions of the indenture with respect to one or more series of debt securities, so long   
 as any such addition, change or elimination shall not apply to any debt securities of any series created prior to the execution of such 
 supplemental indenture and entitled to the benefit of such provision;                                                                   |

| ● | to evidence and provide for the acceptance of appointment by a successor or separate trustee; and |

| ● | to establish the form or terms of debt securities of any series and to make any change that does not adversely affect the interests 
 of the holders of debt securities.                                                                                                  |

With the consent of the holders of at least a
majority in principal amount of debt securities of each series affected by such supplemental indenture (each series voting as one class),
we and the trustee may enter into one or more supplemental indentures for the purpose of adding any provisions to or changing in any manner
or eliminating any of the provisions of the indenture or modifying in any manner the rights of the holders of debt securities of each
such series.

<div align='center'>16</div>

Notwithstanding our rights and the rights of the
trustee to enter into one or more supplemental indentures with the consent of the holders of debt securities of the affected series as
described above, no such supplemental indenture shall, without the consent of the holder of each outstanding debt security of the affected
series, among other things:

| ● | change the final maturity of the principal of, or any installment of interest on, any debt securities; |

| ● | reduce the principal amount of any debt securities or the rate of interest on any debt securities; |

| ● | change the currency in which any debt securities are payable; |

| ● | impair the right of the holders to conduct a proceeding for any remedy available to the trustee; |

| ● | reduce the percentage in principal amount of any series of debt securities whose holders must consent to an amendment or supplemental 
 indenture;                                                                                                                            |

| ● | modify the ranking or priority of the securities; or |

| ● | reduce any premium payable upon the redemption of any debt securities. |

Satisfaction and Discharge of the Indenture; Defeasance

Except to the extent set forth in a supplemental
indenture with respect to any series of debt securities, we, at our election, may discharge the indenture and the indenture shall generally
cease to be of any further effect with respect to that series of debt securities if (a) we have delivered