Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 107

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 107
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, or interruptions in service of trading venues for bitcoin, such                 
 as, for example, digital asset exchange FTX Trading’s freezing of withdrawals and transfers from its accounts in 2022; |

| ● | the filing for bankruptcy protection by, liquidation of, or market concerns about the financial viability                                  
 of digital asset custodians, trading venues, lending platforms, investment funds, or other digital asset industry participants, such as    
 the filing for bankruptcy protection by digital asset trading venues FTX Trading and BlockFi and digital asset lending platforms Celsius   
 Network and Voyager Digital Holdings in 2022, the ordered liquidation of the digital asset investment fund Three Arrows Capital in 2022,   
 the announced liquidation of Silvergate Bank in 2023, the government-mandated closure and sale of Signature Bank in 2023, the placement    
 of Prime Trust, LLC into receivership following a cease-and-desist order issued by the Nevada Department of Business and Industry in 2023, 
 and the exit of Binance Holdings Ltd. from the U.S. market in 2023 as part of its settlement with the Department of Justice and other      
 federal regulatory agencies;                                                                                                               |

| ● | regulatory, legislative, enforcement and judicial actions that adversely affect the price, ownership,                                       
 transferability, trading volumes, legality or public perception of bitcoin, or that adversely affect the operations of or otherwise prevent 
 digital asset custodians, trading venues, lending platforms or other digital assets industry participants from operating in a manner that   
 allows them to continue to deliver services to the digital assets industry;                                                                 |

| ● | further reductions in mining rewards of bitcoin, including block reward halving events, which are events                                     
 that occur after a specific period of time that reduce the block reward earned by “miners” who validate bitcoin transactions,                
 or increases in the costs associated with bitcoin mining, including increases in electricity costs and hardware and software used in mining, 
 that may cause a decline in support for the Bitcoin network;                                                                                 |

| ● | transaction congestion and fees associated with processing transactions on the bitcoin network; |

| ● | macroeconomic changes, such as changes in the level of interest rates and inflation, fiscal and monetary 
 policies of governments, trade restrictions, and fiat currency devaluations;                             |

| ● | developments in mathematics or technology, including in digital computing, algebraic geometry and quantum             
 computing, that could result in the cryptography used by the bitcoin blockchain becoming insecure or ineffective; and |

| ● | changes