Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 396

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 396
---
Treasury Regulations to file an annual information return (Form 8621) containing information regarding our company. Additional explanations
of the PFIC rules are set forth below: this material is complex and may affect different U.S. Holders differently. Accordingly, U.S. Holders
should consult their own tax advisors about the consequences of our company being classified as a PFIC and about what steps, if any, they
might take to lessen the tax impact of our PFIC status on them.

A U.S. Holder who does not
make a timely QEF or mark-to-market election (a “Non-Electing Holder”), as discussed below, will be subject to special tax
rules with respect to any “excess distribution” that you receive and any gain you realize from a sale or other disposition
(including a pledge) of Class A Ordinary Shares. Distributions you receive in a taxable year that are greater than 125% of the average
annual distributions you received during the shorter of the three preceding taxable years or your holding period for the Class A Ordinary
Shares will be treated as an excess distribution. Under these special tax rules:

| ● | the excess distribution or gain will be allocated ratably over your holding period for the Class A Ordinary Shares; |

| ● | the amount allocated to the current taxable year, and any taxable year prior to the first taxable year in which we became a PFIC, will be treated as ordinary income; and |

| ● | the amount allocated to each other year will be subject to the highest tax rate in effect for that year and the interest charge generally applicable to underpayments of tax will be imposed on the resulting tax attributable to each such year. |

It should be noted that, until
such time as we make a distribution, there are no tax consequences to Non-Electing Holders. However, if we ever did make a distribution
it would in all likelihood be an excess distribution (because we would not have previously made any distributions to holders of Class
A Ordinary Shares). At that point, and for all subsequent distributions, the rules described above would apply to Non-Electing Holders.
The tax liability for amounts allocated to years prior to the year of disposition or “excess distribution” cannot be offset
by any net operating losses for such years, and gains (but not losses) realized on the sale of the Class A Ordinary Shares cannot be treated
as capital, even if you hold the Ordinary Shares as capital assets.

A U.S. Holder of stock in