Company: NCEL
Filing Date: 2025-03-03
Form Type: F-4/A
Source: 0001213900-25-018981
Chunk: 531

Company: NewcelX Ltd.
Filing Date: 2025-03-03
Form: F-4/A
Chunk 531
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                 |     |                |
| Kadimastem Ltd. |     |                 |     |                |
| By              |     | /s/ Ronen Twito |     |                |
|                 |     | Name:           |     | Ronen Twito    |
|                 |     | Title:          |     | CEO & Chairman |

Annex A-65 AMENDMENT NO. 2 TO THE AGREEMENT OF MERGER AND PLAN OF REORGANIZATION This Amendment is made as of February 17, 2025 (this “ Amendment ”) to the Agreement of Merger and Plan of Reorganization, dated November 4, 2024 (as previously amended on January 30, 2025, the “ Agreement ”), between Kadimastem Ltd., an Israeli publicly traded company limited by shares (“ Kadimastem ”), NLS Pharmaceutics Ltd., a corporation incorporated under the laws of Switzerland (the “ NLS ”), and NLS Pharmaceuticals (Israel) Ltd., an Israeli company (and together with Kadimastem and NLS, the “ Parties ”). WHEREAS , the Parties are parties to the Agreement, and WHEREAS , the Parties desire to amend the Agreement to clarify their intentions with respect to the terms of the terms thereof. NOW, THEREFORE , for good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties agree as follows: 1.Section 5 is amended to replace subsection 5.16 with the following subsection 5.16: 5.16 Parent Board Designee . 5.16.1During the period (the “ Zwyer Designee Period ”) from the Closing Date until the date that is one year after the Closing Date, Parent shall not take action to remove, or recommend the removal of, Mr. Alexander Zwyer from the Parent’s board without cause therefor, and shall nominate for election and continue to recommend to its shareholders that Mr. Zwyer be elected to serve as a director on Parent’s board of directors; provided, however, that Parent’s obligation to appoint Mr. Zwyer to the Parent’s board of directors, shall terminate upon the expiration of the Zwyer Designee Period. 5.16.2As a condition to the Mr. Zwyer’s appointment to Parent’s board of directors, Mr. Zwyer shall tender an irrevocable resignation that will be effective upon (1) the expiration of the Zwyer