Company: CNTB
Filing Date: 2025-06-10
Form Type: F-3
Source: 0001193125-25-138482
Chunk: 16

Company: Connect Biopharma Holdings Ltd
Filing Date: 2025-06-10
Form: F-3
Chunk 16
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 be expensive, time-consuming and unsuccessful.                                                  |

| • |     | Derivation, interference or other proceedings may be necessary to determine priority of inventions relating to                                                                       
 our current or future Product Candidates, and an unfavorable outcome may require us to cease using the related technology or to attempt to license rights from the prevailing party. |

| • |     | Because of the expense and uncertainty of litigation, we may not be in a position to enforce our intellectual 
 property rights against third parties.                                                                        |

| • |     | Patent reform legislation could increase the uncertainties and costs surrounding the prosecution of our                                                                           
 current and future patent applications or those of our future licensors and the enforcement or defense of our current and future issued patents or those of our future licensors. |

| • |     | Changes in U.S. patent law, PRC patent law or patent laws in other countries could diminish the value of    
 patents in general, thereby impairing our ability to protect our current and any future Product Candidates. |

| • |     | We may not be able to protect our intellectual property rights throughout the world, including in the PRC. |

| • |     | Compulsory standards for remuneration to creators or inventors of the patents they contribute to our business 
 could be considerable.                                                                                        |

| • |     | If we are unable to protect the confidentiality of our trade secrets, our business and competitive position 
 would be harmed.                                                                                            |

| • |     | We may be subject to claims that our employees, consultants or independent contractors have wrongfully used or 
 disclosed confidential information of their former employers or other third parties.                           |

10

| • |     | If our trademarks and trade names are not adequately protected, then we may not be able to build name 
 recognition in our markets of interest and our business may be adversely affected.                    |

| • |     | Any collaboration arrangements that we have or may enter into in the future may not be successful, which could 
 adversely affect our ability to develop and commercialize our products.                                        |

| • |     | Intellectual property rights do not necessarily address all potential threats. |

Risks Related to Doing Business in the PRC

| • |     | Changes in the political and economic policies of the PRC government may materially and adversely affect our                            
 business, financial condition and results of operations and may result in our inability to sustain our growth and expansion strategies. |

| • |     | The PRC government may intervene in or influence our operations in accordance with laws and regulations,