Company: SHPH
Filing Date: 2025-01-15
Form Type: S-1
Source: 0001493152-25-002253
Chunk: 190

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-01-15
Form: S-1
Chunk 190
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 rate                                             |     |                    |    3.64% - 4.93% |    |
| Quoted VWAP                                                         |     | $                  |             1.31 |    |
| Exercise price                                                      |     | $                  |             1.93 |    |
| Probability assessment                                              |     |                    |         0% - 40% |    |
| Illiquidity discount                                                |     |                    |              (14 | %) |
| Time period (years)                                                 |     |                    |      0.08 - 2.28 |    |

| * |     | Based                                                      
 on a Monte Carlo simulation analysis of 250,000 iterations |

| F-18 |

The following table summarizes the changes in the derivative liabilities:

Schedule of Derivative Liabilities

| Fair Value Measurements Using Significant Unobservable 
 Inputs (Level 3)                                       |     | Warrants |          |   |     | Accelerated Feature |        |   |
|:-------------------------------------------------------|:----|:---------|---------:|:--|:----|:--------------------|-------:|:--|
| Balance - December 31, 2023                            |     | $        |  410,660 |   |     | $                   |  3,852 |   |
| Gain on change in fair value                           |     |          | (196,045 | ) |     |                     | (1,817 | ) |
| Balance - March 31, 2024                               |     | $        |  214,615 |   |     | $                   |  2,035 |   |
| Loss (gain) on change in fair value                    |     |          |  145,304 |   |     |                     | (1,531 | ) |
| Balance - June 30, 2024                                |     | $        |  359,919 |   |     | $                   |    504 |   |
| Gain on change in fair value of the derivative         |     |          | (285,812 | ) |     |                     |   (504 | ) |
| Balance - September 30, 2024                           |     | $        |   74,107 |   |     | $                   |      - |   |

Note 8 – Other Related Party transactions

Related Party Transactions

On September 14, 2022, we entered into a manufacturing agreement with TCG GreenChem,