Company: BCDRF
Filing Date: 2025-10-31
Form Type: 424B5
Source: 0001193125-25-260533
Chunk: 341

Company: Banco Santander, S.A.
Filing Date: 2025-10-31
Form: 424B5
Chunk 341
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 an exhibit to the registration statement, each such statement being qualified in all respects by such reference. For further information, you should refer to the registration statement. You can obtain the
full registration statement from the SEC or from us.

INCORPORATION OF DOCUMENTS BY REFERENCE

The SEC allows us to “incorporate by reference” the information that we file with the SEC. This permits us to disclose important
information to you by referring to these filed documents. Any information referred to in this way is considered part of this prospectus, and any information that we file with the SEC after the date of this prospectus will automatically be deemed to
update and supersede this information.

We incorporate by reference the Group’s 2022 Annual Report on Form 20-F for the year ended December 31, 2022 filed with the SEC on March 1, 2023 and “Part 1. Consolidated Directors’ Report-Economic and Financial Review. Section 3” in the
Group’s annual report on Form 20-F for the year ended
December 31, 2021 filed with the SEC on March 1, 2022.

We also incorporate by reference all subsequent annual reports of the
Group filed on Form 20-F and any future filings made with the SEC under Sections 13(a), 13(c), 14 or 15(d) of the Exchange Act and certain reports on Form 6-K, if they
state that they are incorporated by reference into this prospectus, that we furnish to the SEC after the date of this prospectus and until we or any underwriters sell all of the securities.

Upon written or oral request, we will provide free of charge a copy of any or all of the documents that we incorporate by reference into this
prospectus, other than exhibits which are not specifically incorporated by reference into this prospectus. To obtain copies you should contact us at Investor Relations, Ciudad Grupo Santander, Avenida de Cantabria s/n, 28660 Boadilla del Monte,
Madrid, Spain (telephone: (011) 34-91-259-6520).

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CAUTIONARY STATEMENT ON FORWARD-LOOKING STATEMENTS This prospectus, any accompanying prospectus supplement and the documents incorporated by reference into this prospectus contain statements that constitute “forward-looking statements” within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, information regarding: