Company: TEM
Filing Date: 2025-02-25
Form Type: S-1
Source: 0001193125-25-034442
Chunk: 43

Company: Tempus AI, Inc.
Filing Date: 2025-02-25
Form: S-1
Chunk 43
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 2015 Plan, or to require the participant, through payroll withholding, cash payment or otherwise, to satisfy any federal, state, local and foreign taxes that are required to be withheld. We are under no obligation to deliver shares of common stock or to release shares from an escrow or to make any payment in cash until such tax withholding obligations have been satisfied by the participant. Limitations of Liability and Indemnification Matters Our amended and restated certificate of incorporation contains provisions that limit the liability of our current and former directors and officers for monetary damages to the fullest extent permitted by Delaware law. Delaware law provides that directors and officers of a corporation will not be personally liable for monetary damages for any breach of fiduciary duties as directors, except liability for:

| • |     | a director or officers for any breach of the director’s or the officer’s duty of loyalty to the 
 corporation or its stockholders;                                                                |

| • |     | a director or officers for any act or omission not in good faith or that involves intentional misconduct or a 
 knowing violation of law;                                                                                     |

| • |     | a director for unlawful payments of dividends or unlawful stock repurchases or redemptions; |

| • |     | a director or officers for any transaction from which the director or the officer derived an improper personal 
 benefit; or                                                                                                    |

| • |     | an officer in any action by or in the right of the corporation. |

Such limitation of liability does not apply to liabilities arising under federal securities laws and does not affect the availability of equitable remedies such as injunctive relief or rescission. Our amended and restated certificate of incorporation authorizes us to indemnify our directors, officers, employees, and other agents to the fullest extent permitted by Delaware law. Our amended and restated bylaws provide that we are required to indemnify our directors and officers to the fullest extent permitted by Delaware law and may indemnify our other employees and agents. Our amended and restated bylaws also provide that, on 28

satisfaction of certain conditions, we will advance expenses incurred by a director or officer in advance of the final disposition of any action or proceeding, and permit us to secure insurance
on behalf of any officer, director, employee, or other agent. We have entered and expect to continue to enter into agreements to indemnify our directors, executive officers, and other employees as determined by the board of directors. With certain
exceptions, these agreements provide for indemnification for related expenses including attorneys’ fees, judgments