Company: BDRX
Filing Date: 2025-05-12
Form Type: 424B3
Source: 0001214659-25-007340
Chunk: 75

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-05-12
Form: 424B3
Chunk 75
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 require amendment or supplement of the Deposit Agreement or the
form of ADR to ensure compliance therewith, we and the depositary may amend or supplement the Deposit Agreement and the form of ADR (and
all outstanding ADRs) at any time in accordance with such changed laws, rules or regulations. Such amendment or supplement to the Deposit
Agreement in such circumstances may become effective before a notice of such amendment or supplement is given to ADR holders or within
any other period of time as required for compliance.

Notice of any amendment to
the Deposit Agreement or form of ADRs shall not need to describe in detail the specific amendments effectuated thereby, and failure to
describe the specific amendments in any such notice shall not render such notice invalid, provided, however, that, in each such case,
the notice given to the ADR holders identifies a means for ADR holders and beneficial owners to retrieve or receive the text of such amendment
(i.e., upon retrieval from the SEC's, the depositary's or our website or upon request from the depositary).

How may the Deposit Agreement be terminated?

The
depositary may at any time, and shall at our written direction, terminate the Deposit Agreement and the ADRs by mailing notice of such
termination to the registered holders of ADRs at least thirty (30) days prior to the date fixed in such notice for such termination; provided,
however, if the depositary shall have (i) resigned as depositary under the Deposit Agreement, notice of such termination by the depositary
shall not be provided to registered ADR holders unless a successor depositary shall not be operating under the Deposit Agreement within
sixty (60) days of the date of such resignation, and (ii) been removed as depositary under the Deposit Agreement, notice of such termination
by the depositary shall not be provided to registered holders of ADRs unless a successor depositary shall not be operating under the Deposit
Agreement on the 60th day after our notice of removal was first provided to the depositary. Notwithstanding anything to the contrary in
the Deposit Agreement, the depositary may terminate the Deposit Agreement (a) without notifying us, but subject to giving thirty (30)
days' notice to the ADR holders, under the following circumstances: (i) in the event of our bankruptcy, liquidation proceedings or insolvency,
(ii) if our Depositary Shares are delisted from a “national securities exchange” (that has registered with the Commission
under