Company: EDSA
Filing Date: 2025-09-09
Form Type: 424B5
Source: 0001171843-25-005799
Chunk: 18

Company: Edesa Biotech, Inc.
Filing Date: 2025-09-09
Form: 424B5
Chunk 18
---
 does not discuss the potential effects,
whether adverse or beneficial, of any proposed legislation that, if enacted, could be applied on a retroactive basis. This summary is
not binding on the IRS, and the IRS is not precluded from taking a position that is different from, and contrary to, the positions taken
in this summary.

This summary does not address all aspects
of U.S. federal income taxation that may be relevant to particular U.S. Holders in light of their specific circumstances (for example,
U.S. Holders subject to the alternative minimum tax or the Medicare contribution tax on net investment income under the Code) or to holders
that may be subject to special rules under U.S. federal income tax law, including, without limitation:

| ● | dealers in stocks, securities or currencies; |

| ● | securities traders that use a mark-to-market accounting method; |

| ● | banks, underwriters and financial institutions; |

| ● | insurance companies; |

| ● | regulated investment companies; |

| ● | passive foreign investment companies; |

| ● | real estate investment trusts; |

| ● | tax-exempt organizations; |

| ● | retirement plans, individual plans, individual retirement accounts and tax-deferred accounts; |

| ● | partnerships or other pass-through entities for U.S. federal income tax purposes and their partners or members; |

| ● | persons holding common shares as part of a hedging or conversion transaction straddle or other integrated or risk reduction transaction; |

| ● | persons who or that are, or may become, subject to the expatriation provisions of the Code; |

| S-12 |

| ● | persons who are subject to taxing jurisdictions other than, or in addition to, the United States; |

| ● | persons whose functional currency is not the U.S. dollar; |

| ● | persons who acquired common shares in connection with the exercise of employee stock options or otherwise as compensation for services; |

| ● | persons who are subject to special tax accounting rules with respect to our common shares; and |

| ● | direct, indirect or constructive owners of 10% or more of the total combined voting                               
 power of all classes of our voting stock or 10% or more of the total value of shares of all classes of our stock. |

This summary also does not discuss any
aspect of state, local or foreign law, or estate or gift tax law as applicable to U.S. Holders. In addition, this discussion is limited
to U.S