Company: SCLXW
Filing Date: 2025-05-07
Form Type: POS AM
Source: 0001193125-25-115088
Chunk: 5

Company: Scilex Holding Co
Filing Date: 2025-05-07
Form: POS AM
Chunk 5
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 prospectus is , 2025.**</div>

#### TABLE OF CONTENTSPageABOUT THIS PROSPECTUS1CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS3CERTAIN DEFINED TERMS5PROSPECTUS SUMMARY10THE OFFERING21RISK FACTORS23MARKET AND INDUSTRY DATA104USE OF PROCEEDS105DETERMINATION OF OFFERING PRICE106MARKET INFORMATION FOR SECURITIES AND DIVIDEND POLICY107SELECTED HISTORICAL FINANCIAL DATA108MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS110BUSINESS136MANAGEMENT201EXECUTIVE AND DIRECTOR COMPENSATION213CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS239PRINCIPAL SECURITYHOLDERS255SELLING STOCKHOLDER257PLAN OF DISTRIBUTION259MATERIAL U.S. FEDERAL INCOME TAX CONSEQUENCES261DESCRIPTION OF OUR SECURITIES267LEGAL MATTERS284EXPERTS284WHERE YOU CAN FIND MORE INFORMATION284INDEX TO CONSOLIDATED FINANCIAL STATEMENTSF-1You should rely only on the information we have provided in this prospectus, any applicable prospectus supplement and any related free writing prospectus. Neither we nor the Selling Stockholder have authorized anyone to provide you with information different from that contained in this prospectus, any applicable prospectus supplement or any related free writing prospectus. No dealer, salesperson or other person is authorized to give any information or to represent anything not contained in this prospectus, any applicable prospectus supplement or any related free writing prospectus. You must not rely on any unauthorized information or representation. This prospectus is an offer to sell only the securities offered hereby, but only under circumstances and in jurisdictions where it is lawful to do so. You should assume that the information in this prospectus, any applicable prospectus supplement or any related free writing prospectus is accurate only as of the date on the front of the applicable document, regardless of the time of delivery of this prospectus or any sale of a security. Since the date of this prospectus and the documents incorporated by reference into this prospectus, our business, financial condition, results of operations and prospects may have changed.For Investors Outside the United States: The Selling Stockholder is offering to sell, and seeking offers to buy, the securities offered by this prospectus only in jurisdictions where offers and sales are permitted. Neither we nor the Selling Stockholder have done anything that would permit this offering or the