Company: EVGN
Filing Date: 2025-03-27
Form Type: 20-F
Source: 0001178913-25-001092
Chunk: 61

Company: Evogene Ltd.
Filing Date: 2025-03-27
Form: 20-F
Item: Item 4
Chunk 61
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 soybean, following successful
                                                     field trials in 2024 in the US.                                                 
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◾   Pipeline (November 2024) - Lavie Bio announced advancement its bio-fungicide LAV321, targeting Downy Mildew, to pre-commercial stage
                                          following successful 2024 field trial results in Europe.                                      
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◾   Licensing (November 2024) - Lavie Bio announced the cancellation of its licensing agreement with Corteva. Lavie Bio regained full
                       rights and freedom to operate the licensed technology and the lead bio-fungicide candidates.                  
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Biomica
 

•   Clinical Trials - (January 2024) - Biomica enrolled the final patient in its Phase I clinical trial for microbiome-based immuno-oncology
                                                                     drug.                                                                  
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•       Positive Clinical Data Update (May 2024) – Biomica presented positive initial clinical data update from ongoing Phase 1 trial    
    of microbiome-based therapeutic, BMC128, in patients with non-small cell lung cancer, or NSCLC, melanoma, or renal cell carcinoma, or
                                                                     RCC.                                                                
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Casterra
 

◾   Production Agreements (March 2024) – Casterra entered into agreements with seed producers in Brazil and Africa to meet growing
                                                demand for its castor seed varieties.                                             
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◾   Production Agreements (May 2024) – Casterra entered into additional agreements with seed producers, for the production of approximately
                                  500 tons of seeds, to meet existing and growing demand for its castor seeds.                             
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◾   Purchase Orders (June 2024) - Casterra received an additional purchase order valued at approximately $440,000 from an existing customer.
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◾   Production (July 2024) - Casterra announced the completion of a successful castor seed growing and harvesting season in Brazil, which
      will be ready for shipment during the third quarter of 2024, and in addition, Castor harvest season in Africa started as planned.  
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◾   Production (October 2024) - Casterra announced a key milestone in its operational expansion plan in Africa, with completion of first
                shipment of castor seeds grown and processed in Kenya. The shipment, comprising over 100 tons, was delivered            
                                                      to company's customer in Africa.                                                  
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AgPl