Company: BDRX
Filing Date: 2025-09-26
Form Type: F-3
Source: 0001214659-25-014255
Chunk: 78

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-09-26
Form: F-3
Chunk 78
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 it receives will constitute part of the deposited securities and each Depositary
Share will then represent a proportionate interest in such property.

Amendment and Termination

How may the Deposit Agreement be amended?

We may agree with the depositary
to amend the Deposit Agreement and the Depositary Shares without your consent for any reason. ADR holders must be given at least thirty
(30) days’ notice of any amendment that imposes or increases any fees on a per Depositary Share basis, charges or expenses (other
than stock transfer or other taxes and other governmental charges, transfer or registration fees, a transaction fee per cancellation request
(including any cancellation request made through SWIFT, facsimile transmission or any other method of communication), applicable delivery
expenses or other such fees, charges or expenses), or otherwise prejudices any substantial existing right of ADR holders or beneficial
owners. Such notice need not describe in detail the specific amendments effectuated thereby, but must identify to ADR holders and beneficial
owners a means to access the text of such amendment. If an ADR holder or beneficial owner continues to hold an ADR or ADRs, or an interest
therein, after being so notified, such ADR holder and any beneficial owner are deemed to agree to such amendment and to be bound by the
Deposit Agreement as so amended. No amendment, however, will impair your right to surrender your Depositary Shares and receive the underlying
securities, except in order to comply with mandatory provisions of applicable law.

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Any amendments or supplements
that (i) are reasonably necessary (as agreed by us and the depositary) in order for (a) the Depositary Shares to be registered on Form
F-6 under the Securities Act or (b) the Depositary Shares or Ordinary Shares to be traded solely in electronic book-entry form and (ii)
do not in either such case impose or increase any fees or charges to be borne by ADR holders, shall be deemed not to prejudice any substantial
rights of ADR holders or beneficial owners. Notwithstanding the foregoing, if any governmental body or regulatory body should adopt new
laws, rules or regulations that would require amendment or supplement of the Deposit Agreement or the form of ADR to ensure compliance
therewith, we and the depositary may amend or supplement the Deposit Agreement and the form of ADR (and all outstanding ADRs) at any time
in accordance with such changed laws, rules or regulations. Such amendment or supplement to the Deposit Agreement in