Company: CGC
Filing Date: 2025-05-30
Form Type: POS AM
Source: 0001104659-25-054925
Chunk: 77

Company: Canopy Growth Corp
Filing Date: 2025-05-30
Form: POS AM
Chunk 77
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-K. Any statements in any such future filings will automatically be deemed to modify and supersede any information in any document we previously filed with the SEC that is incorporated or deemed to be incorporated herein by reference to the extent that statements in the later filed document modify or replace such earlier statements. Any such statement so modified or superseded shall not be deemed to constitute a part of this prospectus, except as so modified or superseded.

If requested orally or in writing, we will provide to each person, including any beneficial owner, to whom this prospectus supplement is delivered, at no cost, a copy of any or all of the information that has been incorporated by reference in this prospectus supplement but not delivered with this prospectus supplement. Exhibits to the filings will not be sent, however, unless those exhibits have specifically been incorporated by reference into such documents. To obtain a copy of these filings at no cost, you may write to us at the following address:

<div align='center'>Canopy Growth Corporation 
 1 Hershey Drive 
 Smiths Falls, Ontario, Canada K7A 0A8 
 Attention: Chief Legal Officer

S-28</div>

TABLE OF CONTENTS

**The information in this preliminary prospectus is not complete and may be changed. We may not sell these securities until the U.S. Securities and Exchange Commission declares our registration statement effective. This preliminary prospectus is not an offer to sell these securities and we are not soliciting offers to buy these securities in any state or jurisdiction where the offer or sale is not permitted.**

#### SUBJECT TO COMPLETION, DATED MAY 30, 2025

### PROSPECTUS

#### 21,856,810 Common Shares
This prospectus relates to the offer and sale from time to time of up to 21,856,810 of our common shares (the “Shares”) by the selling securityholders listed in the section of this prospectus entitled “Selling Securityholders” (the “Selling Securityholders”), which is comprised of:

1.

349,787 Shares (the “Jetty and TRA Shares”) issued (a) on May 17, 2022 and May 25, 2022 pursuant to an Option Agreement, dated as of May 17, 2022, by and among us, Canopy Oak LLC (“Canopy Oak”), Lemurian, Inc., a California corporation (“Jetty”), and the other parties thereto (the “Primary Option Agreement”); (b) on May