Company: PRTA
Filing Date: 2025-03-28
Form Type: DEF 14A
Source: 0001559053-25-000017
Chunk: 75

Company: PROTHENA CORP PUBLIC LTD CO
Filing Date: 2025-03-28
Form: DEF 14A
Chunk 75
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 Compensation Discussion and Analysis be included in this Proxy Statement and incorporated by reference into the Company’s Annual Report on Form 10-K.

| Paula K. Cobb (Committee Chair) |
| Shane M. Cooke                  |
| Daniel G. Welch                 |

| 44 |     | 2025 PROXY STATEMENT |

#### TABLE OF CONTENTS

### EXECUTIVE COMPENSATION
The following table provides certain information on compensation earned by or awarded to the named executive officers of the Company during our fiscal years 2024, 2023, and 2022.

| Summary Compensation Table - Fiscal Year 2024 |

| Name and Principal Position                        |     | Year |         |     | Salary |         |     | Bonus |   |     |    |           |     | Option Awards(1) |           |     | Non-Equity      
 Incentive Plan  
 Compensation(2) |         |     | All Other       
 Compensation(3) |           |     | Total |           |
| ($)                                                |     |   -$ |         |     |        |         |     | -$    |   |     | -$ |           |     | -$               |           |     | -$              |         |     |                 |           |     |       |           |
| Gene G. Kinney, Ph.D.                              |     | 2024 |         |     |        | 654,129 |     |       | — |     |    |           |     |                  | 6,168,827 |     |                 | 392,478 |     |                 |    15,525 |     |       | 7,230,959 |
| President and Chief Executive Officer              |     | 2023 |         |     |        | 630,547 |     |       | — |     |    |           |     |                  | 6,039,017 |     |                 | 359,412 |     |                 |    14,850 |     |       | 7,043,826 |
| 2022                                               |     |      | 600,521 |     |        |       — |     |       |   |     |    | 5,705,925 |     |                  |   414,359 |     |                 |  15,250 |     |                 | 6,736,055 |     |       |           |
| Tran B. Nguyen                                     |     | 2024 |         |