Company: CMA
Filing Date: 2025-11-25
Form Type: DEFM14A
Source: 0001193125-25-297173
Chunk: 4

Company: COMERICA INC
Filing Date: 2025-11-25
Form: DEFM14A
Chunk 4
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” section beginning on page50 for a discussion of the risks you should consider in evaluating the proposed mergers and how they will affect you. You can also obtain information about Fifth Third and Comerica

from documents that have been filed with the Securities and Exchange Commission that are incorporated into this joint proxy statement/prospectus by reference. On behalf of Fifth Third and Comerica, thank you for your prompt attention to this important matter.

| Timothy N. Spence Chairman, Chief Executive 
 Officer and President Fifth Third Bancorp   |     | Curtis C. Farmer Chairman, Chief Executive  
 Officer and President Comerica Incorporated |

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of the securities to be issued in connection with the first merger or determined if this document is accurate or complete. Any representation to the contrary is a criminal offense. The securities to be issued in the first merger are not savings or deposit accounts or other obligations of any bank or non-banksubsidiary of either Fifth Third or Comerica, and they are not insured by the Federal Deposit Insurance Corporation or any other governmental agency. The accompanying joint proxy statement/prospectus is dated November 25, 2025, and is first being mailed to Fifth Third voting shareholders and Comerica stockholders on or about November 25, 2025.

ADDITIONAL INFORMATION This joint proxy statement/prospectus incorporates important business and financial information about Fifth Third and Comerica from other documents that are not included in or delivered with this joint proxy statement/prospectus. This information is available to you without charge upon your written or oral request. You can obtain the documents incorporated by reference in this joint proxy statement/prospectus through the Securities and Exchange Commission website at http://www.sec.govor by requesting them in writing, by e-mailor by telephone at the appropriate address below:

| if you are a Fifth Third shareholder: 
 Fifth Third Bancorp                   
 38 Fountain Square                    
 Plaza                                 
 MD 1090FV Cincinnati, Ohio 45263      
 Attention: Investor Relations         
 IR@53.com                             
 (866)                                 
 670-0468                              |     | if you are a Comerica stockholder: 
 Comerica Incorporated              
 Comerica Bank                      
 Tower 1717 Main Street, MC 6404    
 Dallas, Texas 75201                
 Attention: Investor Relations      
 InvestorRelations@comerica.com     
 (833) 571-0486                     |

You will not be charged for any of these