Company: AZN
Filing Date: 2025-08-15
Form Type: 6-K
Source: 0001654954-25-009692
Chunk: 1

Company: ASTRAZENECA PLC
Filing Date: 2025-08-15
Form: 6-K
Chunk 1
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 of registered office (if applicable)
**5. Date on which the threshold was crossed or reached**

| 13-Aug-2025 |

#### 6. Date on which Issuer notified
| 14-Aug-2025 |

**7. Total positions of person(s) subject to the notification obligation**

|                                                         | % of voting rights attached to shares (total of 8.A) | % of voting rights through financial instruments (total of 8.B 1 + 
                                                             8.B 2) | Total of both in % (8.A + 8.B) | Total number of voting rights held in issuer |
| Resulting                                               
 situation on the date on which threshold was crossed or 
 reached                                                 |                                             5.009591 |                                                           0.000000 |                       5.009591 |                                     77682857 |
| Position                                                
 of previous notification (if applicable)                |                                             4.984560 |                                                           0.000000 |                       4.984560 |                                              |

**8. Notified details of the resulting situation on the date on which the threshold was crossed or reached**

#### 8A. Voting rights attached to shares
| Class/Type of shares ISIN code(if possible) | Number of direct voting rights (DTR5.1) | Number of indirect voting rights (DTR5.2.1) | % of direct voting rights (DTR5.1) | % of indirect voting rights (DTR5.2.1) |
| GB0009895292 Common                         
 Stock                                       |                                         |                                    63331515 |                                    |                               4.084106 |
| US0463531089                                
 Depository Receipt                          |                                         |                                    14351342 |                                    |                               0.925485 |
| Sub                                         
 Total 8.A                                   |                                77682857 |                                             | 5.009591%                          |                                        |

**8B1. Financial Instruments according to (DTR5.3.1R.(1) (a))**

| Type of financial instrument | Expiration date | Exercise/conversion period | Number of voting rights that may be acquired if the instrument is 
 exercised/converted                                               | % of voting rights |
| Sub                          
 Total 8.B1                   |                 |                            |                                                                   |                    |

**8B2. Financial Instruments with similar economic effect according to (DTR5.3.1R.(1) (b))**

| Type of financial instrument |