Company: EDSA
Filing Date: 2025-03-11
Form Type: 424B3
Source: 0001171843-25-001403
Chunk: 1

Company: Edesa Biotech, Inc.
Filing Date: 2025-03-11
Form: 424B3
Chunk 1
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 “Where You Can Find More Information” and
“Incorporation of Certain Information by Reference” carefully before you invest.

We are a “smaller reporting company” as defined under the federal securities laws and, as such, are eligible for reduced public company reporting requirements. See “Prospectus Summary – Implications of Being a Smaller Reporting Company.”

Investing in our common shares involves a high degree of risk. Before making an investment decision, you should review the information contained under the heading “Risk Factors” in our most recent Annual Report on Form 10-K as such risk factors may be updated in our subsequent reports filed with the Securities and Exchange Commission, which are incorporated by reference herein, and as may be amended, supplemented or superseded from time to time by other reports we file with the Securities and Exchange Commission (the “SEC”).

Neither the SEC nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

<div align='center'>The date of this prospectus is March 11, 2025</div>

### TABLE OF CONTENTS
Page

| ABOUT THIS PROSPECTUS                                |  1 |
| PROSPECTUS SUMMARY                                   |  2 |
| THE OFFERING                                         |  4 |
| RISK FACTORS                                         |  5 |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS |  6 |
| USE OF PROCEEDS                                      |  7 |
| SELLING SHAREHOLDERS                                 |  8 |
| PLAN OF DISTRIBUTION                                 | 12 |
| DESCRIPTION OF SECURITIES                            | 14 |
| LEGAL MATTERS                                        | 18 |
| EXPERTS                                              | 19 |
| WHERE YOU CAN FIND MORE INFORMATION                  | 20 |
| INCORPORATION OF CERTAIN INFORMATION BY REFERENCE    | 21 |

### ABOUT THIS PROSPECTUS
Neither we nor the Selling Shareholders
have authorized anyone to provide you with any information or to make any representations other than those contained in this prospectus
or any applicable prospectus supplement or any free writing prospectuses prepared by or on behalf of us or to which we have referred you.
Neither we nor the Selling Shareholders take responsibility for and can provide no assurance as to the reliability of, any other information
that others may give you. Neither we nor the Selling Shareholders will make an offer to sell these securities in any