Company: APM
Filing Date: 2025-07-15
Form Type: DRS
Source: 0001213900-25-063899
Chunk: 152

Company: Aptorum Group Ltd
Filing Date: 2025-07-15
Form: DRS
Chunk 152
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, with an option to extend by an additional year, for its laboratory space. DiamiR cannot guarantee
that in the future, its landlord will extend its lease. DiamiR cannot be confident that it will find appropriately sized space in and
around New Haven, CT, nor can DiamiR be confident that any new Lab space will be cost effective. There is an inherit risk of losing key
employees if DiamiR is forced to move its Laboratory operation into a new space.

If DiamiR’s information technology or communications systems fail or DiamiR experiences a significant interruption in their operation, its reputation, business and results of operations could be materially and adversely affected.

The efficient operation of
DiamiR’s business is dependent on its information technology and communications systems. The failure of these systems to operate
as anticipated could disrupt its business and result in decreased revenue and increased overhead costs. In addition, DiamiR does not have
complete redundancy for all of its systems and its disaster recovery planning cannot account for all eventualities. DiamiR’s information
technology and communications systems, including the information technology systems and services that are maintained by third party vendors,
are vulnerable to damage or interruption from natural disasters, fire, terrorist attacks, epidemics, pandemics including COVID-19, malicious
attacks by computer viruses or hackers, power loss, failure of computer systems, Internet, telecommunications or data networks. Additionally,
its future clinical services will be largely dependent on its internally developed Laboratory Information Management System or LIMS, which
is its automated basis of managing operations and storing data and customer information. This LIMS was developed to meet its CLIA/CAP
regulatory requirements and was reviewed as part of its most recent CLIA inspection in 2023, which DiamiR passed. Currently the LIM System
is fully operational. If these systems or services become unavailable or suffer a security breach, or are uneconomical or impossible to
update and modify, DiamiR may expend significant resources to address these problems, and its reputation, business and results of operations
could be materially and adversely affected.

Risks Related to Regulation Affecting DiamiR

DiamiR may now or in the future be subject to laws and regulations relating to laboratory testing, which could materially adversely impact its ability to offer its products or services.

The clinical laboratory testing
sector is highly regulated in the United States. DiamiR’s Laboratory is subject to and operated under CLIA regulation (CLIA ID number
(07D109110