Company: IMRX
Filing Date: 2025-09-25
Form Type: 424B5
Source: 0001104659-25-093438
Chunk: 5

Company: Immuneering Corp
Filing Date: 2025-09-25
Form: 424B5
Chunk 5
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 of our ongoing and planned preclinical studies and clinical trials and our research programs, including our ongoing Phase 1/2a clinical trial of atebimetinib and planned registrational trial of atebimetinib in combination with modified gemcitabine/nab-paclitaxel in first-line pancreatic cancer;

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our ability to successfully complete our clinical trials, including our ongoing Phase 1/2a clinical trial of atebimetinib and planned registrational trial of atebimetinib in combination with modified gemcitabine/nab-paclitaxel in first-line pancreatic cancer;

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the risk of substantial delays in completing, if at all, the development and commercialization of our current or future product candidates;

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risks related to adverse events, toxicities or other undesirable side effects caused by our current or future product candidates;

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the risk of delays or difficulties in the enrollment and/or maintenance of patients in clinical trials;

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our substantial reliance on the successful development of our current and future product candidates, as well as our platform, including our proprietary technologies;

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risks related to competition in our industry;

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the market opportunity for our product candidates, if approved;

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risks related to manufacturing;

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risks related to our reliance on third parties;

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risks related to our intellectual property;

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risks related to ongoing and future pandemics or other widespread adverse health events; and

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other important risk factors that could affect the outcome of the events set forth in these statements and that could affect our operating results and financial condition are described under the heading “Risk Factors” contained in this prospectus supplement and in the documents incorporated by reference herein.

Because forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified and some of which are beyond our control, you should not rely on these forward-looking statements as predictions of future events. Moreover, we operate in an evolving environment. New risk factors and uncertainties may emerge from time to time, and it is not possible for management to predict all risk factors and uncertainties. Except as required by applicable law, we do not plan to publicly update or revise any forward-looking statements contained or incorporated by reference herein, whether as a result of any new information, future events, changed circumstances or otherwise.

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### PROSPECTUS SUPPLEMENT SUMMARY
This summary provides a general overview