Company: LEU
Filing Date: 2025-11-06
Form Type: 424B5
Source: 0001104659-25-107429
Chunk: 24

Company: CENTRUS ENERGY CORP
Filing Date: 2025-11-06
Form: 424B5
Chunk 24
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 common stock is listed on The NYSE American LLC, or the NYSE American, under the symbol “LEU.” On November 5, 2025,
the last reported sale price of our common stock was $325.73 per share. The applicable prospectus
supplement will contain information, where applicable, as to the listing of any other securities covered by the prospectus supplement
other than our common stock on the NYSE American or any other securities exchange.

Investing in any of our securities involves a high degree of risk. Please read carefully the section entitled “Risk Factors” on page9 of this prospectus, the “Risk Factors” section contained in the applicable prospectus supplement and the information included and incorporated by reference in this prospectus.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

<div align='center'>The date of this prospectus is November 6, 2025

TABLE OF CONTENTS</div>

Page

| About This Prospectus                             |  1 |
| Where You Can Find More Information               |  2 |
| Information We Incorporate By Reference           |  3 |
| Special Note Regarding Forward-Looking Statements |  4 |
| Centrus Energy Corp.                              |  8 |
| Risk Factors                                      |  9 |
| Use Of Proceeds                                   | 10 |
| Description Of Capital Stock                      | 11 |
| Description Of Debt Securities                    | 13 |
| Description Of Warrants                           | 19 |
| Description Of Rights                             | 22 |
| Description Of Units                              | 23 |
| Plan Of Distribution                              | 24 |
| Legal Matters                                     | 26 |
| Experts                                           | 26 |

<div align='center'>About This Prospectus</div>

This prospectus is part of
a registration statement on Form S-3 that we filed with the Securities and Exchange Commission, or the SEC, as a “well-known
seasoned issuer” as such term is defined in Rule 405 of the Securities Act of 1933, as amended, or the Securities Act, using
a “shelf” registration or continuous offering process. Under this shelf registration process, we may, from time to time, offer
and sell any combination of the securities described in this prospectus in one or more offerings.

This prospectus provides a
general description of the securities we may