Company: RGNX
Filing Date: 2025-03-13
Form Type: POSASR
Source: 0001193125-25-053917
Chunk: 28

Company: REGENXBIO Inc.
Filing Date: 2025-03-13
Form: POSASR
Chunk 28
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 of all holders of such debt securities money, non-callable U.S. government securities, or a combination thereof that will generate enough cash to pay and discharge the principal, premium, if any, and interest on the debt securities on their various due dates; |

| • |     | we must deliver to the trustee a legal opinion of our counsel confirming that, under current U.S. federal income                                                                                                    
 tax law, we may make the above deposit without causing the holders to be taxed on the debt securities any differently than if we did not make the deposit and repaid the debt securities ourselves at maturity; and |

| • |     | we must deliver to the trustee certain documentation stating that all conditions precedent to covenant defeasance 
 have been complied with.                                                                                          |

If we accomplish covenant defeasance, holders can still look to us for repayment of the debt securities if there were a shortfall in the trust deposit or the trustee is prevented from making payment. In fact, if one of the remaining events of default occurs (such as our bankruptcy) and the debt securities become immediately due and payable, there might be a shortfall. Depending on the event causing the default, holders may not be able to obtain payment of the shortfall. Legal Defeasance We can make the deposit described below and be legally released from all payment and other obligations on the debt securities of a particular series, which we refer to as “legal defeasance.” In that event, we and any guarantor shall have been deemed to have been discharged from obligations with respect to such debt securities and related guarantees, respectively. In order to achieve legal defeasance, we must do the following:

| • |     | we must deposit in trust for the benefit of all holders of such debt securities money, non-callable U.S. government securities, or a combination thereof that will generate enough cash to pay and discharge the principal, premium, if any, and interest on the debt securities on their various due dates; |

| • |     | we must deliver to the trustee a legal opinion confirming that there has been a change in current U.S. federal                                                                                                                                        
 tax law or an Internal Revenue Service ruling that allows us to make the above deposit without causing the holders to be taxed on the debt securities any differently than if we did not make the deposit and repaid the debt securities ourselves at 
 maturity; and                                                                                                                                                                                                                                         |

| • |     | we must deliver to the trustee a legal opinion and officers’ certificate stating that all conditions 
 precedent to legal defeasance have