Company: PFSA
Filing Date: 2025-08-25
Form Type: 424B3
Source: 0001213900-25-080387
Chunk: 305

Company: Profusa, Inc.
Filing Date: 2025-08-25
Form: 424B3
Chunk 305
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ments The Company operates as one operating segment. The Company’s chief operating decision maker (“CODM”) is its Chief Executive Officer, Ben Hwang, who reviews financial information presented on a consolidated net loss basis as reported on the consolidated condensed statement of operations and comprehensive loss in order to make decisions about allocating resources and assessing performance for the entire Company. The CODM also utilizes the Company’s long -rangeplan, which includes product development roadmaps and long -rangefinancial models, as a key input to resource allocation. The CODM function approves of key operating and strategic decisions. The CODM function views the Company’s operations and manages its business on a consolidated basis and as a single reportable operating segment. The CODM function is regularly provided with the following significant segment expenses. Significant expenses include research and development and general and administrative expenses, which are each separately presented in the Company’s consolidated condensed statements of operations and comprehensive loss. The CODM reviews significant expenses within both the research and development and the general and administrative categories. Other segment items within net loss include interest income, interest expense and loss on change in fair value of related party loan. See the consolidated condensed financial statements for other financial information regarding the Company’s operating segment.

F-51

PROFUSA, INC. AND SUBSIDIARY
NOTES TO THE CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
(UNAUDITED) Note 13 — Segments (cont.)

|                                                                                 |     | Three Months Ended 
 June 30,           |   2025 |   |     |   |   2024 |   |
|:--------------------------------------------------------------------------------|:----|:-------------------|-------:|:--|:----|:--|-------:|:--|
| Government grant revenue                                                        |     | $                  |      — |   |     | $ |     25 |   |
| Operating expenses:                                                             |     |                    |        |   |     |   |        |   |
| Research personnel compensation costs, including stock-based compensation       |     |                    |    320 |   |     |   |    385 |   |
| CRO and regulatory costs                                                        |     |                    |      — |   |     |   |      — |   |
| Administrative personnel compensation costs, including stock-based compensation |     |                    |    401 |   |     |   |    350 |   |
| Rent and office costs                                                           |     |                    |    118 |   |     |