Company: TEM
Filing Date: 2025-08-08
Form Type: S-3ASR
Source: 0001193125-25-175993
Chunk: 76

Company: Tempus AI, Inc.
Filing Date: 2025-08-08
Form: S-3ASR
Chunk 76
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 of our Class A common stock sold and the market price
at which they are sold, the actual total public offering amount, commissions and proceeds to us, if any, are not determinable at this time. There can be no assurance that we will be able to sell any shares under the sales agreement or fully utilize
the sales agreement with the sales agents as a source of financing.

We currently intend to use the net proceeds from the sale of the
securities under this prospectus for general corporate purposes, which may include acquisitions or strategic investments in complementary businesses or technologies, working capital, operating expenses and capital expenditures.

We will have broad discretion over how to use the net proceeds from this offering. We intend to invest the net proceeds to us from this
offering that are not used as described above in investment-grade, interest-bearing instruments.

7

PLAN OF DISTRIBUTION

We entered into the sales agreement with the sales agents on August 8, 2025, which we filed as an exhibit to a report filed under the
Exchange Act and incorporate by reference herein. In accordance with the terms of the sales agreement, we may issue and sell shares of our Class A common stock under this prospectus having an aggregate offering price of up to $500,000,000, from
time to time through or to Morgan Stanley, Cantor, TD Securities and/or Allen, as sales agent or principal, in each case severally and not jointly.

Sales of shares of our Class A common stock, if any, under this prospectus may be made in negotiated transactions, including block trades
sales Class A common stock that would constitute a “block” within the meaning of Rule 10b-18(a)(5) under the Exchange Act , or by any method permitted by law deemed to be an “at the market” offering as defined in
Rule 415(a)(4) of the Securities Act, including without limitation sales made through Nasdaq or on any other existing trading market for the Class A common Stock, or by any other method permitted by law. We may instruct the sales agents
not to sell Class A common stock if the sales cannot be effected at or above the price designated by us from time to time. We or the sales agents may suspend the offering of Class A common stock upon notice and subject to other conditions.

The sales agents will offer our Class A common stock subject to the terms and conditions of the sales agreement as agreed upon by us
and the sales agents. Each time we wish to issue and sell Class A common