Company: PFSA
Filing Date: 2025-04-28
Form Type: S-4/A
Source: 0001213900-25-035718
Chunk: 296

Company: Profusa, Inc.
Filing Date: 2025-04-28
Form: S-4/A
Chunk 296
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:------|-------:|:--|
| Lumee Oxygen            |     | $     | — |     | $     | 10.91 |     | $     | 42.63 |   |     | $     |  96.96 |   |     | $     | 176.73 |   |     | $     | 282.25 |   |     | $     | 359.87 |   |     | $     | 413.85 |   |     | $     | 444.89 |   |     | $     | 467.13 |   |
| Annual growth rate (%)  |     |       |   |     |       |       |     |       |   291 | % |     |       |    127 | % |     |       |     82 | % |     |       |     60 | % |     |       |     28 | % |     |       |     15 | % |     |       |      8 | % |     |       |      5 | % |
| Lumee Glucose           |     | $     | — |     | $     |  0.96 |     | $     | 57.07 |   |     | $     | 174.22 |   |     | $     | 308.46 |   |     | $     | 502.75 |   |     | $     | 703.86 |   |     | $     | 844.63 |   |     | $     | 929.09 |   |     | $     | 975.54 |   |
| Annual growth rate (%)  |     |       |   |     |       |       |     |       | 5,873 | % |     |       |    205 | % |     |       |     77 | % |     |       |     63 | % |     |       |     40 | % |     |       |     20 | % |     |       |     10 | % |     |       |      5 | % |

The list below provides a further explanation of the assumptions included in the Updated Projections: Revenue Assumptions •Regarding the revenue assumptions for Lumee Oxygen, Profusa’s management assumed that the Company will attain regulatory approval in the US by late 2026, with commercialization in EU based on the CE approval and