Company: PCRX
Filing Date: 2025-02-27
Form Type: S-8
Source: 0001396814-25-000043
Chunk: 0

Company: Pacira BioSciences, Inc.
Filing Date: 2025-02-27
Form: S-8
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission on February 27, 2025</div>

#### Registration No. 333-

### UNITED STATES

### SECURITIES AND EXCHANGE COMMISSION

#### Washington, D.C. 20549
#### ______________________

#### FORM S-8

### REGISTRATION STATEMENT UNDER THE

#### SECURITIES ACT OF 1933
#### ______________________

#### PACIRA BIOSCIENCES, INC.
<div align='center'>(Exact name of registrant as specified in its charter)</div>

| Delaware                                              |     | 51-0619477         |
| (State or other jurisdiction of                       
 incorporation or organization)                        |     | -I.R.S. Employer   
 Identification No. |
| 5401 West Kennedy Boulevard, Suite 890                
 Tampa, Florida 33609                                  |     |                    |
| (Address and zip code of principal executive offices) |     |                    |

<div align='center'>Pacira BioSciences, Inc. Amended and Restated 2014 Inducement Plan (Full title of the plan)</div>

#### Frank D. Lee

#### Chief Executive Officer

#### Pacira BioSciences, Inc.

#### 5401 West Kennedy Boulevard, Suite 890

#### Tampa, Florida 33609
<div align='center'>(Name and address of agent for service)

(813) 553-6680

(Telephone number, including area code, of agent for service)

______________________
Copy to:</div>

#### Jason Day

#### Ned A. Prusse

#### Jonathan S. Schulman

#### Perkins Coie LLP

#### 1900 Sixteenth Street, Suite 1400

#### Denver, Colorado 80202
<div align='center'>(303) 291-2300</div>

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act:

| Large accelerated filer | x |     | Accelerated filer         | o |
| Non-accelerated filer   | o |     | Smaller reporting company | o |
|                         |   |     | Emerging growth company   | o