Company: AZN
Filing Date: 2025-09-29
Form Type: 6-K
Source: 0001104659-25-094039
Chunk: 13

Company: ASTRAZENECA PLC
Filing Date: 2025-09-29
Form: 6-K
Chunk 13
---
eca Shares and AstraZeneca ADSs that were acquired by individuals on the vesting of share awards prior to the Effective Time. Individuals who hold AstraZeneca Shares or AstraZeneca ADSs through EquatePlus (the company’s share plan nominee system) will hold AstraZeneca DIs or AstraZeneca Shares (as applicable) in this way following the Effective Time. Participants in the AstraZeneca Share Plans will be contacted separately about these changes.

Further details are set out in Part III ( Settlement and Dealings in AstraZeneca Shares following the Settlement System Migration ) of this document.

<div align='center'>10</div>

**TABLE OF CONTENTS

Certificated Shareholders (other than those holding Affiliate Shares)**

At the Effective Time, the AstraZeneca Shares held in certificated form by Shareholders (other than Affiliate Shares) will also be transferred to and deposited with DTC.

CSN Eligible Certificated Shareholders will be automatically enrolled in the CSN Facility and will hold and may settle their interests in AstraZeneca Shares through CREST in the form of AstraZeneca DIs through the CSN Facility following implementation of the Settlement System Migration.

Where the CSN Facility cannot be made available to certain certificated Shareholders for regulatory or jurisdictional reasons, the underlying AstraZeneca Shares held by such CSN Non-Eligible Certificated Shareholders will be transferred into a temporary election agent facility within DTC managed by the Election Agent. During the specified Holding Period, such CSN Non-Eligible Certificated Shareholders will be able to elect how their interests in AstraZeneca Shares are to be held going forward. Any CSN Non-Eligible Certificated Shareholders who have not made an election by the end of the Holding Period will have their AstraZeneca Shares delivered to them in certificated form.

Further details of the CSN Facility and the procedures and options applicable to CSN Non-Eligible Certificated Shareholders are set out in Part III ( Settlement and Dealings in AstraZeneca Shares following the Settlement System Migration ) of this document.

#### Affiliate Shares
Affiliate Shares (whether in certificated or uncertificated form) will not be eligible for deposit and clearing in DTC and will need to be held outside the DTC clearing system until certain criteria are met, with depositary receipts issued to the relevant Affiliate Shareholders on a one