Company: SION
Filing Date: 2025-02-07
Form Type: 424B4
Source: 0001193125-25-022709
Chunk: 349

Company: Sionna Therapeutics, Inc.
Filing Date: 2025-02-07
Form: 424B4
Chunk 349
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 |     | $             | (148,549 | ) |

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements. F-32

SIONNA THERAPEUTICS, INC. CONDENSED CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ DEFICIT (in thousands, except share amounts) (Unaudited)

|                                           |     | Series Seed     
 Preferred Stock 
 Shares          |           |     | Amount |        |     | Series A        
 Preferred Stock 
 Shares          |           |     | Amount |        |     | Series B        
 Preferred Stock 
 Shares          |            |     | Amount |         |     | Common Stock 
 Shares       |           |     | Amount |   |     | Additional 
 Paid-In    
 Capital    |       |     | Accumulated   
 Other         
 Comprehensive 
 Income (Loss) |     |   |     | Accumulated 
 Deficit     |          |   |     | Total         
 Stockholders’ 
 Deficit       |          |   |
|:------------------------------------------|:----|:----------------|----------:|:----|:-------|-------:|:----|:----------------|----------:|:----|:-------|-------:|:----|:----------------|-----------:|:----|:-------|--------:|:----|:-------------|----------:|:----|:-------|--:|:----|:-----------|------:|:----|:--------------|----:|:--|:----|:------------|:---------|:--|:----|:--------------|---------:|:--|
| Balance as of December 31, 2022           |     |                 | 3,963,963 |     | $      | 13,014 |     |                 | 5,704,161 |     | $      | 25,235 |     |                 | 11,370,621 |     | $      | 110,791 |     |              | 2,792,929 |     | $      | 2 |     | $          | 2,225 |     | $             | (16 | ) |     | $           | (72,135  | ) |     | $             |  (69,924 | ) |
| Exercise of common stock options          |     |                 |         — |     |        |      — |     |                 |         — |     |        |