Company: INMB
Filing Date: 2025-06-30
Form Type: 424B5
Source: 0001213900-25-059298
Chunk: 0

Company: Inmune Bio, Inc.
Filing Date: 2025-06-30
Form: 424B5
Chunk 0
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| PROSPECTUS SUPPLEMENT                 | Filed Pursuant to Rule 424(b)(5) |
| (To the Prospectus Dated May 1, 2024) | Registration No. 333-279036      |

<div align='center'>3,000,000 Shares of Common Stock</div>

We are offering 3,000,000
shares of our common stock, par value $0.001 per share (the “common stock”). The offering price per share of common stock
is $6.30 for 3,000,000 shares of common stock purchased by two healthcare focused institutional investors.

Our common stock is listed
on The Nasdaq Capital Market (“Nasdaq”) under the symbol “INMB.” On June 26, 2025, the last reported sale price
of our common stock on Nasdaq was $6.28 per share.

Investing in our securities involves a high degree of risk. You should review carefully the risks and uncertainties referenced under the heading “Risk Factors” on page S-4 of this prospectus supplement and on page 5 of the accompanying prospectus and contained in our filings made with the Securities and Exchange Commission (the “SEC”).

Neither the SEC nor any state securities commission has approved or disapproved of these securities or passed upon the accuracy or adequacy of this prospectus supplement or the accompanying prospectus. Any representation to the contrary is a criminal offense.

We have retained A.G.P./Alliance
Global Partners (“Alliance” or the “Placement Agent”) as placement agent in connection with this offering. The
Placement Agent has agreed to use its reasonable best efforts to place the securities offered by this prospectus supplement and the accompanying
prospectus. The Placement Agent is not purchasing or selling any securities pursuant to this prospectus supplement or the accompanying
prospectus, nor are we requiring any minimum purchase or sale of any specific number of shares. We have agreed to pay the Placement Agent
the fees set forth in the table below:

|                                 |     | Per Share |       |     | Total |                |
|:--------------------------------|:----|:----------|------:|:----|:------|---------------:|
| Offering price                  |     | $         |  6.30 |     | $     |  18,900,000.00 |
| Placement Agent fees (1)        |     | $         | 0.441 |     | $     | 1,323, 000