Company: CERO
Filing Date: 2025-12-05
Form Type: S-1
Source: 0001213900-25-118817
Chunk: 275

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-12-05
Form: S-1
Chunk 275
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 be more or less than the number of shares being offered by this prospectus. |

| (3) | Applicable percentage ownership                                                        
 is based on 21,102,671 shares of our Common Stock outstanding as of November 24, 2025. |

| (4) | The business address of Keystone                                                                                                              
 is 139 Fulton Street, Suite 412, New York, NY 10038. Keystone’s principal business is that of a private investor. Ranz Group, LLC,            
 a Delaware limited liability company, is the managing member of Keystone and the beneficial owner of 97% of the membership interests          
 in Keystone. Fredric G. Zaino is the managing member of Ranz Group, LLC and has sole voting control and investment discretion over securities 
 beneficially owned directly by Keystone and indirectly by Ranz Group, LLC. We have been advised that none of Mr. Zaino, Ranz Group, LLC       
 or Keystone is a member of the Financial Industry Regulatory Authority (“FINRA”) or an independent broker-dealer, or an affiliate             
 or associated person of a FINRA member or independent broker-dealer. The foregoing should not be construed in and of itself as an admission   
 by Mr. Zaino as to beneficial ownership of the securities beneficially owned directly by Keystone and indirectly by Ranz Group, LLC.          |

163 CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS Other than the compensation agreements and other arrangements described under the sections entitled “ Executive Compensation” and “ Director Compensation” above and the transactions described below, since January 1, 2023, there has not been and there is not currently proposed, any transaction or series of similar transactions to which we were, or will be, a party in which:

| ● | the amount involved exceeded,                                                                                           
 or will exceed, $120,000 (or, if less, 1% of the average of our total asset amounts at December 31, 2023 and 2024); and |

| ● | any director, executive officer,                                                                                                     
 holder of 5% or more of any class of our capital stock or any member of the immediate family of, or entities affiliated with, any of 
 the foregoing persons, had, or will have, a direct or indirect material interest.                                                    |

CERo Relationships and Related Party Transactions Collaboration and Option Agreement On March 3, 2020, Legacy CERo entered into a collaboration and option agreement (“Collaboration Agreement”) with a