Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119846
Chunk: 13

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 13
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 Stock, each with an exercise price of $0.01 per share, issued to Oramed pursuant to the Scilex-Oramed SPA. |

| • |     | “Private Warrants” means the 6,840,000 warrants sold in a private placement to Vickers                                                                                                                                              
 Venture Fund VI Pte Ltd and Vickers Venture Fund VI (Plan) Pte Ltd consummated on January 11, 2021 (of which 2,736,000 were forfeited pursuant to the Sponsor Support Agreement and 3,104,000 were transferred to Sorrento pursuant 
 to the Warrant Transfer Agreement, in each case in connection with the Business Combination).                                                                                                                                       |

6

| • |     | “public shareholders” means the holders of the public shares. |

| • |     | “public shares” means the Vickers Ordinary Shares which were sold as part of the IPO, whether                                                                                                                                                           
 they were purchased in the IPO or in the aftermarket, including any of our Initial Shareholders to the extent that they purchase such public shares (except that our Initial Shareholders will not have conversion or tender rights with respect to any 
 public shares they own).                                                                                                                                                                                                                                |

| • |     | “Public Warrants” means the redeemable warrants that were included in the Units that entitle the           
 holder of each whole warrant to purchase one Vickers Ordinary Share at a price of $402.50 per whole share. |

| • |     | “SCLX JV” means SCLX Stock Acquisition JV LLC, our indirect wholly owned subsidiary. |

| • |     | “SEC” means the U.S. Securities and Exchange Commission. |

| • |     | “Securities Act” means the Securities Act of 1933, as amended. |

| • |     | “Series A Certificate of Designations” means the Certificate of Designations of the Company,                          
 designating the series of preferred stock, par value $0.0001 per share, of the Company as “Series A Preferred Stock”. |

| • |     | “Series A Preferred Stock” means the preferred stock, par value $0.0001 per share, of the             
 Company, designated as Series A Preferred Stock pursuant to the Series A Certificate of Designations. |

| • |     | “Sorrento” means Sorrento Therapeutics, Inc. |

| • |     | “Sorrento Group” means Sorrento together with its affiliates, subsidiaries, successors and 
 assigns (