Company: EDSA
Filing Date: 2025-05-28
Form Type: S-8
Source: 0001171843-25-003499
Chunk: 4

Company: Edesa Biotech, Inc.
Filing Date: 2025-05-28
Form: S-8
Chunk 4
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en Martineau Dumoulin LLP (included in Exhibit 5.1)             |      |                           |             |           |         |      |             |            |     | X        |
| 23.2    |                     | Consent of Independent Registered Public Accounting Firm                       |      |                           |             |           |         |      |             |            |     | X        |
| 24.1    |                     | Power of Attorney (included on signature page)                                 |      |                           |             |           |         |      |             |            |     | X        |
| 107     |                     | Filing Fee Table                                                               |      |                           |             |           |         |      |             |            |     | X        |

<div align='center'>SIGNATURES</div>

Pursuant to the requirements of
the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements
for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized,
in the City of Markham, Province of Ontario, on May 28, 2025.

| EDESA BIOTECH, INC. |                                                           |
| By:                 | /s/ Pardeep Nijhawan                                      |
|                     | Pardeep Nijhawan                                          |
|                     | Director, Chief Executive Officer and Corporate Secretary |

<div align='center'>POWER OF ATTORNEY</div>

Each person whose signature
appears below constitutes and appoints Pardeep Nijhawan and Peter J. Weiler, and each of them, as such person’s true and
lawful attorney-in-fact and agent with full power of substitution and resubstitution, for such person in such person’s name,
place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this
Registration Statement, and to file the same, with all exhibits thereto, and all documents in connection therewith, with the
Securities and Exchange Commission, granting unto each said attorney-in-fact and agent full power and authority to do and perform
each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as
such person might or could do in person, hereby ratifying and confirming all that any said attorney-in-fact and agent, or