Company: TXG
Filing Date: 2025-02-13
Form Type: S-8
Source: 0001770787-25-000015
Chunk: 0

Company: 10x Genomics, Inc.
Filing Date: 2025-02-13
Form: S-8
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission on February 13, 2025.</div>

#### Registration No. 333-

### UNITED STATES

### SECURITIES AND EXCHANGE COMMISSION

#### Washington, D.C. 20549
#### _________________________________

#### FORM S-8

### REGISTRATION STATEMENT

#### UNDER

#### THE SECURITIES ACT OF 1933
#### __________________________________

#### 10x Genomics, Inc.
<div align='center'>(Exact name of registrant as specified in its charter)</div>

#### __________________________________

| Delaware                        
 (State or other jurisdiction of 
 incorporation or organization)  |     | 45-5614458          
 (I.R.S. Employer    
 Identification No.) |

#### 6230 Stoneridge Mall Road

#### Pleasanton, California 94588
<div align='center'>(Address of Principal Executive Offices) (Zip Code)</div>

#### 10x Genomics, Inc. 2019 Omnibus Incentive Plan
<div align='center'>10x Genomics, Inc. 2019 Employee Stock Purchase Plan

(Full title of the Plans)</div>

#### Serge Saxonov

#### Chief Executive Officer

#### 10x Genomics, Inc.

#### 6230 Stoneridge Mall Road

#### Pleasanton, California 94588

#### Telephone: (925) 401-7300
<div align='center'>(Name and address and telephone number, including area code, of agent for service)

With copies to:</div>

#### Sarah B. Axtell, Esq.

#### Latham and Watkins LLP
140 Scott Drive

#### Menlo Park, California 94025
<div align='center'>(650) 328-4600</div>

#### __________________________________

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

| Large accelerated filer |     | ☒ |     | Accelerated filer         |     | ☐ |
| Non-accelerated filer   |     | ☐ |     | Smaller reporting company |     | ☐ |
|                         |     |   |     |