Company: SMNR
Filing Date: 2025-06-11
Form Type: S-4/A
Source: 0001193125-25-139124
Chunk: 851

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-06-11
Form: S-4/A
Chunk 851
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 |   |        2024 |   |
|:------------------------------------------------------------------------|:----|:-------------------|------------:|:--|:----|:--|------------:|:--|
| Net loss (in thousands)                                                 |     | $                  |        (665 | ) |     | $ |      (1,506 | ) |
| Net loss per share — basic and diluted                                  |     | $                  |       (0.01 | ) |     | $ |       (0.01 | ) |
| Weighted average number of shares during the period — basic and diluted |     |                    | 160,000,000 |   |     |   | 160,000,000 |   |

Note 9. Subsequent Events Scilex Bio JV On April 17, 2025, Scilex and IPMC Company formed a joint venture, Scilex Bio, Inc. (“Scilex Bio”), to develop and commercialize a next-generation reversible MAO-B Inhibitor, a novel inhibitor of aberrant GABA production in reactive astrocytes for the treatment of obesity and neurodegenerative diseases including Alzheimer’s disease. Scilex contributed 5.0 million shares of Semnur Common Stock owned by Scilex to Scilex Bio in exchange for a 60% ownership interest in Scilex Bio and IPMC Company contributed certain assets to Scilex Bio in exchange for a 40% ownership interest in Scilex Bio. F-97

#### Annex A-1

### AGREEMENT AND PLAN OF MERGER

#### dated as of August 30, 2024

#### by and among

#### Denali Capital Acquisition Corp.,

#### Denali Merger Sub Inc.,

#### and

#### Semnur Pharmaceuticals, Inc.
TABLE OF CONTENTS

|                                                         |     |                                                                      |     | Page   |
| ARTICLE I DEFINITIONS                                   |     |                                                                      |     | A-1-2  |
| ARTICLE II DOMESTICATION                                |     |                                                                      |     | A-1-13 |
| 2.1                                                     |     | Domestication                                                        |     | A-1-13 |
| 2.2                                                     |     | Plan of Domestication                                                |     | A-1-13 |
| ARTICLE III MERGER                                      |     |                                                                      |     | A-1-13 |
| 3.1                                                     |     | Merger                                                               |     | A-1-13