Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 392

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 392
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 purposes of this brief
discussion, a “U.S. Holder” is a holder who, for U.S. federal income tax purposes, is a beneficial owner of Class A Ordinary
Shares or warrants and that is:

| (1) | an individual citizen or resident of the United States;                                                                                                                                                                                                                                                                                 |
| (2) | a corporation, or other entity taxable as a corporation, created or organized in or under the laws of the United States, any state therein or the District of Columbia;                                                                                                                                                                 |
| (3) | an estate, the income of which is subject to U.S. federal income taxation regardless of its source; or                                                                                                                                                                                                                                  |
| (4) | a trust, (i) if a court within the United States is able to exercise primary supervision over its administration and one or more “U.S. persons” (within the meaning of the Code) have the authority to control all of its substantial decisions, or (ii) if a valid election is in effect for the trust to be treated as a U.S. person. |

U.S. Holders are encouraged
to consult their tax advisors concerning the U.S. federal, state, local and foreign tax consequences of purchasing, owning and disposing
of Class A Ordinary Shares in their particular circumstances.

Taxation of Distributions

Subject to the discussion
below under “Passive Foreign Investment Company (PFIC) Rules,” a U.S. Holder will be required to include in gross income as
dividend income the gross amount of any distributions paid on Class A Ordinary Shares (including any amount of taxes withheld), other
than certain pro ratadistributions of Class A Ordinary Shares, to the extent paid out of our current or accumulated earnings and
profits (as determined under U.S. federal income tax principles). Distributions in excess of our current and accumulated earnings and
profits would be treated as a non-taxable return of capital to the extent of the U.S. Holder’s adjusted tax basis in the Class A
Ordinary Shares and thereafter as a gain from the sale of the Class A Ordinary Shares. However, because we do not calculate our earnings
and profits under U.S. federal income tax principles, we expect that distributions generally will be reported to U.S. Holders as dividends.

In case of a U.S. Holder that
is a corporation, dividends paid on the Class A Ordinary Shares will be subject to regular corporate rates and will not be eligible for
the “dividends received” deduction generally allowed to corporate shareholders with respect