Company: RGNX
Filing Date: 2025-03-13
Form Type: POSASR
Source: 0001193125-25-053917
Chunk: 26

Company: REGENXBIO Inc.
Filing Date: 2025-03-13
Form: POSASR
Chunk 26
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 protect its interests relating to any debt securities, the following must occur:

| • |     | the holder must give the trustee written notice that an event of default has occurred and remains uncured; |

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| • |     | the holders of at least 25% in aggregate principal amount of all outstanding debt securities of the relevant                                                                                            
 series must make a written request that the trustee take action because of the default and must offer reasonable indemnity to the trustee against the cost and other liabilities of taking that action; |

| • |     | the trustee must not have taken action for 60 days after receipt of the above notice and offer of indemnity; and |

| • |     | the holders of a majority in aggregate principal amount of the debt securities must not have given the trustee a 
 direction inconsistent with the above notice during that 60-day period.                                          |

However, a holder is entitled at any time to bring a lawsuit for the payment of money due on its debt securities on or after the due date. Each year, we will furnish to each trustee a written statement of certain of our officers certifying that to their knowledge we are in compliance with the indenture and the debt securities, or else specifying any default. Waiver of Default The holders of a majority in aggregate principal amount of the relevant series of debt securities may waive a default or event of default for such series of debt securities. If this happens, the default will be treated as if it had not occurred. Merger or Consolidation Under the terms of an indenture, we may be permitted to consolidate or merge with another entity. We may also be permitted to sell all or substantially all of our assets to another entity. However, typically we may not take any of these actions unless all the following conditions are met:

| • |     | if we do not survive such transaction or we convey, transfer or lease our properties and assets substantially as                                                                                                                                        
 an entirety, the acquiring company must be a corporation, limited liability company, partnership or trust, or other corporate form, organized under the laws of the United States, any state of the United States or the District of Columbia, and such 
 company must agree to be legally responsible for our debt securities;                                                                                                                                                                                   |

| • |     | alternatively, we must be the surviving company; |

| • |     | immediately after the transaction no event of default, or event that, after notice or lapse of time or both, 
 would constitute an event of default, will have occurred or be continuing;                                   |

| •