Company: NDRA
Filing Date: 2025-10-30
Form Type: 424B5
Source: 0001213900-25-103705
Chunk: 27

Company: ENDRA Life Sciences Inc.
Filing Date: 2025-10-30
Form: 424B5
Chunk 27
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 It
is also not possible to predict the nature of any such additional authorities, how additional legislation or regulatory oversight might
impact the ability of digital asset markets to function or the willingness of financial and other institutions to continue to provide
services to the digital assets industry, nor how any new regulations or changes to existing regulations might impact the value of digital
assets generally and cryptocurrency specifically. The consequences of increased or different regulation of digital assets and digital
asset activities could adversely affect the market price of cryptocurrency and in turn adversely affect the market price of our common
stock. Moreover, the risks of engaging in a digital asset treasury strategy are relatively novel and have created, and could
continue to create, complications due to the lack of experience that third parties have with companies engaging in such a strategy, such
as increased costs of director and officer liability insurance or the potential inability to obtain such coverage on acceptable terms
in the future.

<div align='center'>S-15</div>

Cryptocurrency holdings are less liquid than our existing cash and cash equivalents and may not be able to serve as a source of liquidity for us to the same extent as cash and cash equivalents.

Historically, the crypto markets have been characterized
by significant volatility in price; limited liquidity and trading volumes compared to sovereign currencies markets; relative anonymity;
a developing regulatory landscape; potential susceptibility to market abuse and manipulation; compliance and internal control failures
at exchanges; and various other risks inherent in its entirely electronic, virtual form and decentralized network. During times of market
instability, we may not be able to sell our cryptocurrency at favorable prices or at all. Further, cryptocurrency which we hold with our
custodians does not enjoy the same protections as are available to cash or securities deposited with or transacted by institutions subject
to regulation by the Federal Deposit Insurance Corporation or the Securities Investor Protection Corporation. Additionally, pursuant to
the asset management agreement we intend to enter into with the asset manager, we are currently and may generally be unable to enter into
term loans or other capital raising transactions collateralized by our unencumbered cryptocurrency or otherwise generate funds using our
cryptocurrency holdings, including in particular during times of market instability or when the price of cryptocurrency has declined significantly.
If we are unable to sell our cryptocurrency, enter into additional capital raising transactions using cryptocurrency as collateral, or
otherwise generate funds using our cryptocurrency holdings, or if we are forced to sell our cryptocurrency at a significant loss, in order
to meet our working capital requirements, our business and financial condition could be negatively