Company: SCYX
Filing Date: 2025-04-30
Form Type: DEF 14A
Source: 0001140361-25-016641
Chunk: 2

Company: SCYNEXIS INC
Filing Date: 2025-04-30
Form: DEF 14A
Chunk 2
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ially invited to attend the meeting online. Whether or not you expect to attend the meeting, please vote over the telephone or on the internet as instructed in these materials, or complete, date, sign and return the enclosed proxy, as promptly as possible in order to ensure your representation at the meeting. A return envelope (which is postage prepaid if mailed in the United States) has been provided for your convenience. Even if you have voted by proxy, you may still vote online if you attend the meeting. Please note, however, that if your shares are held of record by a broker, bank or other nominee and you wish to vote at the meeting, you should contact that record holder for instructions on how to vote your shares.

TABLE OF CONTENTS

SCYNEXIS, Inc. 1 Evertrust Plaza, 13 thFloor Jersey City, New Jersey, 07302 (201) 884-5485 PROXY STATEMENT FOR THE 2025 ANNUAL MEETING OF STOCKHOLDERS JUNE 25, 2025 Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting of Stockholders to Be Held on June 25, 2025, at 9:30 a.m. Eastern time at www.virtualshareholdermeeting.com/SCYX2025. The proxy statement and annual report to stockholders are available at www.proxyvote.com Meeting Agenda

| Proposal No. 
 1            
 2            |     | Proposal                                                                                                                                                                                                                      
 Election of the SCYNEXIS Board of Directors’ seven nominees as directors to serve until the 2026 Annual Meeting of Stockholders and until their successors are duly elected and qualified                                     
 Ratification of the selection, by the Audit Committee of the Board of Directors, of Deloitte & Touche LLP as the independent registered public accounting firm of SCYNEXIS, Inc. for its fiscal year ending December 31, 2025 |     | Board Vote                         
 Recommendation                     
 For each SCYNEXIS director nominee 
 For                                |
|:-------------|:----|:------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:----|:-----------------------------------|
| 3            |     | Advisory approval of the compensation of our named executive officers as disclosed in this proxy statement                                                                                                                    |     | For                                |

On or about April 30, 2025, we intend to first mail to most of our stockholders at the close of business on the Record Date a Notice of Internet Availability of Proxy Materials (the “Notice”) instead of a paper copy of the proxy materials