Company: SXTPW
Filing Date: 2025-02-06
Form Type: 424B5
Source: 0001213900-25-010772
Chunk: 39

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-02-06
Form: 424B5
Chunk 39
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054 shares of common stock outstanding.

<div align='center'>S-23

PLAN OF DISTRIBUTION</div>

Pursuant to an engagement letter agreement between and H.C. Wainwright & Co., LLC dated August 30, 2024, as amended on September 3, 2024 and January 24, 2025 (the “Engagement Agreement”), we
have engaged H.C. Wainwright & Co., LLC to act as our exclusive Placement Agent to solicit offers to purchase the shares of common
stock offered by this prospectus supplement and accompanying prospectus. The Placement Agent is not purchasing or selling any securities,
nor is it required to arrange for the purchase and sale of any specific number or dollar amount of securities, other than to use its reasonable
“best efforts” to arrange for the sale of all of the securities offered hereby. We have entered into securities purchase agreement
directly with the investors in connection with this offering for the sale of all of the shares of common stock offered hereby (and the
issuance of the Private Placement Warrants, which are not being offered herein, but are being issued in a separate concurrent offering,
exempt from registration under the Securities Act). We will only sell to such investors who have entered into the securities purchase
agreement with us.

The Engagement Agreement provides that the Placement Agent’s obligations are subject to conditions contained in the Engagement Agreement.

We will deliver the securities being issued to the investors upon receipt
of investor funds for the purchase of the securities offered pursuant to this prospectus supplement. We expect to deliver the securities
being offered pursuant to this prospectus supplement on or about February 6, 2025, subject to satisfaction of customary closing conditions.

Placement Agent Fees, Commissions and Expenses

Upon the closing of this offering, we will pay the Placement Agent a cash transaction fee equal to 7.5% of the aggregate gross cash proceeds to us from the sale of the shares of common stock in the offering and a management fee equal to 1.0% of the aggregate gross cash proceeds to us from the sale of the shares of common stock in the offering. Pursuant to the Engagement Agreement, we will agree to reimburse the Placement Agent for certain non-accountable expenses in the amount of $15,000 and a clearing fee in the amount of $10,000.

The following table shows the offering price, Placement Agent fees
and proceeds, before expenses, to us.

|                                  |     | Per Share |        |     | Total