Company: CGC
Filing Date: 2025-05-30
Form Type: POS AM
Source: 0001104659-25-054925
Chunk: 81

Company: Canopy Growth Corp
Filing Date: 2025-05-30
Form: POS AM
Chunk 81
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 CONTENTS

TABLE OF CONTENTS Prospectus

| ​                                                    | ​ | ​ | Page |   |    |   | ​ |
| About this Prospectus                                | ​ | ​ | ​    | ​ |  1 | ​ | ​ |
| Cautionary Note Regarding Forward Looking Statements | ​ | ​ | ​    | ​ |  2 | ​ | ​ |
| Risk Factors                                         | ​ | ​ | ​    | ​ |  3 | ​ | ​ |
| The Company                                          | ​ | ​ | ​    | ​ |  4 | ​ | ​ |
| Use of Proceeds                                      | ​ | ​ | ​    | ​ |  5 | ​ | ​ |
| Selling Securityholders                              | ​ | ​ | ​    | ​ |  6 | ​ | ​ |
| Plan of Distribution                                 | ​ | ​ | ​    | ​ | 11 | ​ | ​ |
| Legal Matters                                        | ​ | ​ | ​    | ​ | 13 | ​ | ​ |
| Experts                                              | ​ | ​ | ​    | ​ | 14 | ​ | ​ |
| Incorporation of Certain Documents by Reference      | ​ | ​ | ​    | ​ | 15 | ​ | ​ |
| Enforceability of Civil Liabilities                  | ​ | ​ | ​    | ​ | 16 | ​ | ​ |

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TABLE OF CONTENTS

### ABOUT THIS PROSPECTUS
On June 5, 2024, we filed with the U.S. Securities and Exchange Commission (the “SEC”) a registration statement on Form S-3 (File No. 333-279949), as amended on May 29, 2025 and on May 30, 2025 (as amended, the “Registration Statement”) utilizing a shelf registration process relating to certain securities, including the securities described in this prospectus. This prospectus is part of the Registration Statement.

Neither we nor the Selling Securityholders have authorized any dealer, agent or other person to give any information or to make any representation other than those contained or incorporated by reference in this prospectus and, if applicable, any accompanying prospectus supplement or any free writing prospectus. Neither we nor the Selling Securityholders take any responsibility for, and provide no assurance as to the reliability of, any other information that others may give you. This prospectus and, if applicable, any accompanying prospectus supplement or any free writing prospectus, do not constitute an offer to sell