Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 368

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 368
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         — |    |     |   |    — |   |
| All executive officers and directors as a group (4 persons) |     |                    | 3,836,177 |    |     |   | 85.1 | % |

| * | less than 1%. |

| (1) | Represents Mr. Mireskandari’s option to purchase common stock that can be vested and exercised within the next 60 days. |

| (2) | Since November 2023, Mr. Anthony has been serving as a financial consultant and immediately following the Merger, he will step into the role of Chief Financial Officer. |

<div align='center'>211

PRO FORMA
PRINCIPAL STOCKHOLDERS OF THE COMBINED COMPANY</div>

The following table provides
information anticipated as of the Merger Closing, regarding beneficial ownership of 5% or more of Aptorum Delaware’s common stock
by: (i) each person known to Aptorum Delaware who beneficially owns more than five percent of Aptorum Delaware’s common stock; (ii)
each of the expected officers and directors of the Combined Company. The following table assumes [ ] shares of
Aptorum Delaware Common Stock will be issued in the Merger.

We have determined beneficial
ownership in accordance with the rules of the SEC. These rules generally attribute beneficial ownership of securities to persons
who possess sole or shared voting power or investment power with respect to those securities. In addition, the rules include shares of
common stock issuable pursuant to the exercise of stock options that are either immediately exercisable or exercisable within 60 days
after September 30, 2025. These shares are deemed to be outstanding and beneficially owned by the person holding those options for the
purpose of computing the percentage ownership of that person, but they are not treated as outstanding for the purpose of computing the
percentage ownership of any other person. The shares in the tables does not, however, constitute an admission that the named stockholder
is a direct or indirect beneficial owner of those shares.

Unless otherwise indicated,
the address for each beneficial owner is [ ].

| NAME OF BENEFICIAL OWNER                                    |     | NUMBER OF    
 SHARES       
 BENEFICIALLY 
 OWNED        |     | PERCENTAGE   
 OF SHARES    
 OUTSTANDING  
 BENEFICIALLY 
 OWNED        |
| Directors and Executive Officers:                           |     |              |     |              |
| Ian Huen, Chief Executive Officer & Director