Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 84

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 84
---
 attention from other aspects of our business, could put our patents at risk of being invalidated or interpreted narrowly and our patent
applications at risk of not issuing and could provoke third parties to assert claims against us. We may not prevail in any lawsuits that
we initiate and the damages or other remedies awarded, if any, may not be commercially meaningful. Accordingly, our efforts to enforce
our intellectual property rights around the world may be inadequate to obtain a significant commercial advantage from the intellectual
property that we develop or license and may adversely impact our business.

In addition, we also face the
risk that our products are imported or reimported into markets with relatively higher prices from markets with relatively lower prices,
which would result in a decrease of sales and any payments we receive from the affected market. Recent developments in U.S. patent
law have made it more difficult to stop these and related practices based on theories of patent infringement.

If we are unable to protect the confidentiality of our trade secrets, the value of our technology could be materially adversely affected and our business could be harmed.

We rely heavily on trade secrets
and confidentiality agreements to protect our unpatented know-how, technology and other confidential proprietary information, and to maintain
our competitive position. However, trade secrets and know-how can be difficult to protect. In particular, we anticipate that with respect
to our technologies, these trade secrets and know-how will over time be disseminated within the industry through independent development,
the publication of journal articles describing the methodology, and the movement of personnel from academic to industry scientific positions.

<div align='center'>45</div>

In addition to pursuing patents
on our technology, we take steps to protect our intellectual property and proprietary technology by entering into agreements, including
confidentiality agreements, non-disclosure agreements and intellectual property assignment agreements, with our employees, consultants,
academic institutions, corporate partners and, when needed, our advisers. However, we cannot be certain that such agreements have been
entered into with all relevant parties, and we cannot be certain that our trade secrets and other confidential proprietary information
will not be disclosed or that competitors or other third parties will not otherwise gain access to our trade secrets or independently
develop substantially equivalent information and techniques. For example, any of these parties may breach the agreements and disclose
our proprietary information, including our trade secrets, and we may not be able to obtain adequate remedies for such breaches. Such agreements
may not be enforceable or may not provide meaningful protection for our trade secrets or other proprietary information in the event