Company: EPR-PE
Filing Date: 2025-11-05
Form Type: 424B5
Source: 0001193125-25-266433
Chunk: 20

Company: EPR PROPERTIES
Filing Date: 2025-11-05
Form: 424B5
Chunk 20
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 underwriters or their affiliates act as lenders and/or agents under our unsecured revolving credit facility and, accordingly,
may receive an amount in excess of 5% of the net proceeds from this offering. See “Underwriting (Conflicts of Interest)—Conflicts of Interest.”

S-17

Capitalization The following table sets forth our cash and cash equivalents and capitalization as of September 30, 2025, on:

| • |     | an actual basis; and |

| • |     | an as adjusted basis to give effect to the sale of the notes offered hereby and application of the net proceeds thereof as 
 described under “Use of Proceeds.”                                                                                         |

This information should be read in conjunction with, and is qualified in its entirety by, the consolidated financial statements and schedules and notes thereto and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” included in our Quarterly Report on Form 10-Qfor the nine months ended September 30, 2025, incorporated by reference in this prospectus supplement.

|                                               |     | As of September 30, 2025 |           |   |     |          |           |   |
|:----------------------------------------------|:----|:-------------------------|----------:|:--|:----|:---------|----------:|:--|
| (dollars in thousands)                        
 (unaudited)                                   |     | Actual                   |           |   |     | As       
 adjusted |           |   |
| Cash, cash equivalents and restricted cash(1) |     | $                        |    29,692 |   |     | $        |   189,020 |   |
| Debt:                                         |     |                          |           |   |     |          |           |   |
| Unsecured revolving credit facility(1)(2)     |     |                          |   379,000 |   |     |          |         — |   |
| 4.560% Senior Notes due 2026                  |     |                          |   179,597 |   |     |          |   179,597 |   |
| 4.750% Senior Notes due 2026                  |     |                          |   450,000 |   |     |          |   450,000 |   |
| 4.500% Senior Notes due 2027                  |     |                          |   450,000 |   |     |          |   450,000 |   |
| 4