Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 0

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 0
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As filed with the Securities and Exchange Commission on November 5, 2025 Registration No. 333-[ ] UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-4 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 FIFTH THIRD BANCORP (Exact Name of Registrant as Specified in Its Charter)

| Ohio                            |     |                         6021 |     | 31-0854434         |
| (State or other jurisdiction of 
 incorporation or organization)  |     | -Primary Standard Industrial 
   Classification Code Number |     | -I.R.S. Employer   
 Identification No. |

Fifth Third Center 38 Fountain Square Plaza Cincinnati, Ohio 45263 (800) 972-3030 (Address, including zip code, and telephone number, including area code, of Registrant’s principal executive offices) Christian Gonzalez Executive Vice President and Chief Legal Officer Fifth Third Center 38 Fountain Square Plaza Cincinnati, Ohio 45263 (800) 972-3030 (Name, address, including zip code, and telephone number, including area code, of agent for service) Copies to:

| H. Rodgin Cohen          
 Mitchell S. Eitel        
 Sullivan & Cromwell LLP  
 125 Broad Street         
 New York, New York 10004 
 (212) 558-4000           |     | Von E. Hays                                             
 Senior Executive Vice President and Chief Legal Officer 
 Comerica Bank Tower                                     
 1717 Main Street, MC 6404                               
 Dallas, Texas 75201                                     
 (833) 571-0486                                          |     | Edward D. Herlihy              
 Matthew M. Guest               
 Wachtell, Lipton, Rosen & Katz 
 51 West 52nd Street            
 New York, New York 10019       
 (212) 403-1000                 |

Approximate date of commencement of proposed sale of the securities to the public:As soon as practicable after this Registration Statement is declared effective and upon completion of the mergers described herein. If the securities being registered on this Form are being offered in connection with the formation of a holding company and there is compliance with General Instruction G, check the following box. ☐ If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.