Company: NCNA
Filing Date: 2025-06-18
Form Type: F-3/A
Source: 0001193125-25-142565
Chunk: 43

Company: NuCana plc
Filing Date: 2025-06-18
Form: F-3/A
Chunk 43
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| • |     | the identity of the warrant agent for the warrants and of any other depositaries, execution or paying agents, 
 transfer agents, registrars or other agents;                                                                  |

| • |     | the proposed listing, if any, of the warrants or any securities purchasable upon exercise of the warrants on any 
 securities exchange;                                                                                             |

| • |     | if applicable, the date from and after which the warrants and the ADSs and/or debt securities will be separately 
 transferable;                                                                                                    |

| • |     | if applicable, the minimum or maximum amount of the warrants that may be exercised at any one time; |

| • |     | information with respect to book-entry procedures, if any; |

| • |     | the anti-dilution provisions of the warrants, if any; |

| • |     | any redemption or call provisions, if any; |

| • |     | whether the warrants may be sold separately or with other securities as parts of units; and |

| • |     | any additional terms of the warrants, including terms, procedures and limitations relating to the exchange and 
 exercise of the warrants.                                                                                      |

Transfer Agent and Registrar The transfer agent and registrar for any warrants will be set forth in the applicable prospectus supplement. 35

DESCRIPTION OF RIGHTS General We may issue rights to our shareholders to purchase our ordinary shares represented by ADSs or the other securities described in this prospectus. We may offer rights separately or together with one or more additional rights, debt securities, ordinary shares represented by ADSs, or warrants, or any combination of those securities in the form of units, as described in the applicable prospectus supplement. Each series of rights will be issued under a separate rights agreement to be entered into between us and a bank or trust company, as rights agent. The rights agent will act solely as our agent in connection with the certificates relating to the rights of the series of certificates and will not assume any obligation or relationship of agency or trust for or with any holders of rights certificates or beneficial owners of rights. The following description sets forth certain general terms and provisions of the rights to which any prospectus supplement may relate. The particular terms of the rights to which any prospectus supplement may relate and the extent, if any, to which the general provisions may apply to the rights so offered will be described in the applicable prospectus supplement. To the extent that any particular terms of the rights, rights agreement or rights certificates described in a prospectus supplement differ from