Company: APM
Filing Date: 2025-07-15
Form Type: DRS
Source: 0001213900-25-063906
Chunk: 218

Company: Aptorum Group Ltd
Filing Date: 2025-07-15
Form: DRS
Chunk 218
---
ylococcus aureus and MRSA can cause a variety of problems ranging from skin infections and sepsis to pneumonia and bloodstream infections. It is estimated that about one out of every three people (33%) carry Staphylococcus aureus in their nose, usually without any illness; about two in a hundred (2%) carry MRSA (source: https://www.cdc.gov/mrsa/tracking/index.html). Both adults and children may carry MRSA. Most MRSA infections occur in people who have been in hospital or other health care settings, such as nursing homes and dialysis centers (source: https: // www.mayoclinic.org /diseases -conditions / mrsa /symptoms -causes / syc -20375336), which is known as Healthcare -AssociatedMRSA (“HA -MRSA”). HA -MRSAinfections are typically associated with invasive procedures or devices, such as surgeries, intravenous tubing or artificial joints. Another type of MRSA infection, known as Community -AssociatedMRSA (“CA -MRSA”), has occurred in wider community among healthy people. It often begins as a painful skin boil and spreads by skin -to -skincontact. About 85% of serious, invasive MRSA infections 115 are healthcare associated infections ( https://www.cdc.gov/media/pressrel/2007/r071016.htm). The incidence of CA -MRSAvaries according to population and geographic location. In the U.S., more than 94,000 people develop serious MRSA infection and about 19,000 patients die as a result each year ( https: // www.cdc.gov / media / pressrel / 2007 / r071016.htm). According to the US Centers for Disease Control and Prevention (“CDC”), Staphylococcus aureus, including MRSA, caused about 11% of healthcare -associatedinfections in 2011 (source: http: // www.healthcommunities.com /mrsa -infection / incidence.shtml). Each year in the U.S., around one out of every twenty -fivehospitalized patients contracts at least one infection in the hospital (N Engl J Med. 2014, 27;370(13):1198 -208). In the U.S., there were over 80,000 invasive MRSA infections and 11,285 related deaths in 2011 (source: https: // edition.cnn.com / 2013 / 06 / 28 / us /mrsa -