Company: BCDRF
Filing Date: 2025-01-08
Form Type: 424B5
Source: 0001193125-25-003514
Chunk: 2

Company: Banco Santander, S.A.
Filing Date: 2025-01-08
Form: 424B5
Chunk 2
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. See “ Risk Factors” beginning on page S-13of this prospectus supplement, page 7 of the accompanying prospectus as well as those discussed under the heading “Risk Factors” in the Group’s Annual Report on Form 20-Ffor the year ended December 31, 2023 and under the heading “Part 2. Supplemental Information—Item 4. Risk Factors” in the Group’s Report on Form 6-Kfiled with the SEC on July 26, 2024 (Accession No. 0000891478-24-000092),which are incorporated by reference herein. The Notes are not intended to be offered, sold or otherwise made available and should not be offered, sold or otherwise made available to retail clients (as defined in Directive 2014/65/EU of the European Parliament and of the Council on Markets in Financial Instruments (“MiFID II”) and Regulation (EU) No. 2017/565 as it forms part of the domestic law of the United Kingdom by virtue of the European Union (Withdrawal) Act of 2018 (“EUWA”)) in the European Economic Area or in the United Kingdom. Prospective investors are referred to the section headed “Important Information” on page S-vof this prospectus supplement. Neither the U.S. Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the accuracy or adequacy of this prospectus supplement or the accompanying prospectus. Any representation to the contrary is a criminal offense.

| Per 2030 Fixed Rate Note    |     | Price to Public |       100.000 | % |     | Underwriting 
 Discount     |     0.300 | % |     | Proceeds to us    
 (before expenses) |        99.700 | % |
|:----------------------------|:----|:----------------|--------------:|:--|:----|:-------------|----------:|:--|:----|:------------------|--------------:|:--|
| Total 2030 Fixed Rate Notes |     | $               | 1,000,000,000 |   |     | $            | 3,000,000 |   |     | $                 |   997,000,000 |   |
| Per 2035 Fixed Rate Note    |     |                 |       100.000 | % |     |              |     0.450 | % |     |                   |        99.550