Company: HURA
Filing Date: 2025-05-23
Form Type: 424B3
Source: 0001193125-25-125499
Chunk: 273

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-05-23
Form: 424B3
Chunk 273
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and otherwise subject Kineta to fines and other liability under laws and regulations that protect the privacy and security of personal information, which could result in significant legal and financial exposure and reputational damages that could
potentially have an adverse effect on Kineta’s business.

The costs of mitigating cybersecurity risks are significant and are likely
to increase in the future. These costs include, but are not limited to, retaining the services of cybersecurity providers; compliance costs arising out of existing and future cybersecurity, data protection and privacy laws and regulations; and costs
related to maintaining redundant networks, data backups and other damage-mitigation measures. Kineta also cannot be certain that its existing insurance coverage will continue to be available on acceptable terms or in amounts sufficient to cover the
potentially significant losses that may result from a security incident or breach or that the insurer will not deny coverage of any future claim.

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Kineta’s operations as a global company subject it to various risks, and Kineta’s failure to manage these risks could adversely affect its business, results of operations, cash flows, financial condition and/or prospects. Kineta faces significant operational risks as a result of doing business globally, such as:

| • |     | fluctuations in currency exchange rates; |

| • |     | potentially adverse tax consequences, including the complexities of foreign value-added tax systems, tax           
 inefficiencies related to Kineta’s corporate structure and potential restrictions on the repatriation of earnings; |

| • |     | export restrictions, trade regulations and foreign tax laws; |

| • |     | customs clearance and shipping delays; |

| • |     | the burdens of complying with a wide variety of foreign laws and different legal standards; and |

| • |     | increased financial accounting and reporting burdens and complexities. |

If one or more of these risks are realized, it could have a material adverse effect on Kineta’s business, results of operations, cash flows, financial condition and/or prospects. Kineta or the third parties upon whom it depends may be adversely affected by earthquakes, fires or other natural disasters and Kineta’s business continuity and disaster recovery plans may not adequately protect Kineta from a serious disaster. If earthquakes, fires, other natural disasters, terrorism and similar unforeseen events beyond Kineta’s control prevent it from using all or a significant portion of its headquarters or other facilities, it may be difficult or, in certain cases, impossible for Kineta to continue its business for a substantial period of time. Kineta does not have a disaster recovery or business continuity