Company: CERO
Filing Date: 2025-04-01
Form Type: NT 10-K
Source: 0001213900-25-026702
Chunk: 1

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-04-01
Form: NT 10-K
Chunk 1
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 10-Q or subject distribution report    
 on Form 10-D, or portion thereof, will be filed on or before the fifth calendar day following the prescribed due date; and                 |                                                                                  |
|   | -c |    | The accountant’s statement or other exhibit required by Rule 12b-25(c) has been attached if applicable.                                    |                                                                                  |

<div align='center'>PART III — NARRATIVE</div>

State below in reasonable detail the reasons why Forms
10-K, 20-F, 11-K, 10-Q, 10-D, N-CEN, N-CSR, or the transition report or portion thereof, could not be filed within the prescribed time
period.

CERo Therapeutics Holdings, Inc. (the “Registrant”)
was unable, without unreasonable effort or expense, to file its Annual Report on Form 10-K for the year ended December 31, 2024 (the “Annual
Report”) by the March 31, 2025 filing date applicable to smaller reporting companies. The Registrant’s independent registered
public accounting firm requires additional time to complete its review of the financial statements for the year ended December 31, 2024
to be incorporated in the Annual Report. The Registrant anticipates that it will file the Annual Report no later than the fifteenth calendar
day following the prescribed filing date.

<div align='center'>PART IV — OTHER INFORMATION</div>

| (1) | Name and telephone number of person to contact in regard to this notification. |

| Chris Ehrlich |     |        415 |     | 994-0582          |
| (Name)        |     | -Area Code |     | -Telephone Number |

| (2) | Have all other periodic reports required under Section 13 or 15(d) of the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940 during the preceding 12 months or for such shorter period that the registrant was required to file such report(s) been filed? If answer is no, identify report(s). ☒ Yes ☐ No |

| (3) | Is it anticipated that any significant change in results of operations from the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof? ☒ Yes ☐ No |

| If so: attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate