Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 165

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 165
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 investors became accustomed to low volatility. The resulting easing of financial
conditions supported economic growth, but it also contributed to a buildup of financial vulnerabilities. With inflation at multi-decade
highs, monetary authorities in advanced economies are accelerating the pace of policy normalization. Policymakers have continued to tighten
policy against a backdrop of rising inflation and currency pressures, albeit with notable differences across regions. Global financial
conditions have tightened notably this year, leading to capital outflows. Amid heightened economic and geopolitical uncertainties, investors
have aggressively pulled back from risk-taking and adjusted their investment preferences generally. Key gauges of systemic risk, such
as higher dollar funding costs and counterparty credit spreads, have risen. There is a risk of a disorderly tightening of financial conditions
that may be amplified by vulnerabilities built over the years.

In addition, our business,
growth, financial condition or results of operations could be materially adversely affected by instability or changes in a country’s
or region’s economic conditions; inflation; changes in laws or regulations or in the interpretation of existing laws or regulations,
whether caused by a change in government or otherwise; increased difficulty of conducting business in a country or region due to actual
or potential political or military conflict; or action by the U.S. or foreign governments that may restrict our ability to transact
business in a foreign country or with certain foreign individuals or entities. A possible slowdown in global trade caused by increasing
tariffs or other restrictions could decrease consumer or corporate confidence and reduce consumer, government and corporate spending in
countries inside or outside the U.S., which could adversely affect our operations. Climate-related events, including extreme weather
events and natural disasters and their effect on critical infrastructure in the U.S. or internationally, could have similar adverse
effects on our operations, users, or third-party suppliers.

PIPE Transaction

Initial Note

On February 11, 2025,
NorthView executed a Securities Purchase Agreement (the “PIPE Subscription Agreement”) with Ascent Partners Fund LLC (“Ascent”,
and together with any additional investors who become parties to the PIPE Subscription Agreement, the “PIPE Investors”). Pursuant
to the PIPE Subscription Agreement, the PIPE Investors are expected, subject to the conditions relating to such purchase set forth in
the PIPE Subscription Agreement, to purchase from NorthView senior secured convertible notes in an aggregate principal amount of up to
$22,222,222 (the “PIPE Convertible Notes”) for a an aggregate purchase price of up to $20,000,000, reflecting a 10%