Company: CNTB
Filing Date: 2025-06-10
Form Type: F-3
Source: 0001193125-25-138482
Chunk: 17

Company: Connect Biopharma Holdings Ltd
Filing Date: 2025-06-10
Form: F-3
Chunk 17
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 which    
 could result in a material change in our operations and significantly and adversely impact the value of our ADSs. |

| • |     | Compliance with the PRC’s Data Security Law, Cybersecurity Review Measures, Personal Information                                                                                                             
 Protection Law, regulations and guidelines relating to the multi-level protection scheme and any other future laws and regulations may entail significant expenses and could materially affect our business. |

| • |     | PRC laws and regulations governing our current business operations are sometimes vague and uncertain, and                                                                                                                                          
 therefore, these risks may result in a material negative change in our subsidiaries’ operations, significant depreciation of the value of our ADSs, or a hindrance of our ability to offer or continue to offer our securities to investors, which 
 could cause the value of the securities of investors to decrease.                                                                                                                                                                                  |

| • |     | The approval of and the filing with the China Securities Regulatory Commission may be required under a PRC 
 regulation in connection with any future offerings of our securities in the U.S. market.                   |

| • |     | Certain PRC regulations may make it more difficult for us to pursue growth through acquisitions. Any failure                                                                                                                                       
 by us to comply with PRC anti-monopoly laws and regulations may result in governmental investigations or enforcement actions, litigation or claims against us and could have an adverse effect on our business, financial condition and results of 
 operations.                                                                                                                                                                                                                                        |

| • |     | Governmental control of currency conversion may limit our ability to remit funds out of the PRC and utilize 
 our capital or future revenues effectively and could affect the value of any investment in our ADSs.        |

| • |     | PRC regulation of loans to, and direct investments in, PRC entities by offshore holding companies may restrict 
 or prevent us from making loans or additional capital contributions to our PRC subsidiaries.                   |

| • |     | Any failure to comply with PRC regulations regarding the registration requirements for employee share                          
 incentive plans may subject our equity incentive plan participants or us to fines and other legal or administrative sanctions. |

| • |     | PRC regulations relating to offshore investment activities by PRC residents may limit our PRC                                                                                                
 subsidiaries’ ability to change their registered capital or distribute profits to us or otherwise expose us or our PRC resident beneficial owners to liability and penalties under PRC laws. |

| • |     | We may be treated as a resident enterprise for PRC tax purposes under the PRC Enterprise Income Tax Law, and 
 we may therefore