Company: AZN
Filing Date: 2025-09-29
Form Type: 6-K
Source: 0001104659-25-094039
Chunk: 29

Company: ASTRAZENECA PLC
Filing Date: 2025-09-29
Form: 6-K
Chunk 29
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 Shares on a one for one basis.

AstraZeneca DRs will be constituted and issued under the terms of the agreement made by the DR Depositary constituting the AstraZeneca DRs (the

#### “DR Terms”
), which will govern the relationship between the DR Depositary and the holders of AstraZeneca DRs.

**Transfers of AstraZeneca Shares underlying AstraZeneca DRs**

Subject to compliance with applicable securities laws (including any applicable holding period), following the Effective Time an Affiliate Shareholder may instruct the DR Depositary to cancel all or a portion of its AstraZeneca DRs in order to effect a transfer of its underlying Affiliate Shares by the DR Depositary to the DTC Nominee, which will, at the election of the relevant Affiliate Shareholder, credit book entry interests in respect of such Affiliate Shares to: (i) the relevant DTC participant nominated by the Affiliate Shareholder, in order to facilitate transfers of such Affiliate Shares by way of book entry through the DTC clearing system; (ii) the DTC participant account of the DI Custodian (acting as custodian of such book entry interests for the DI Depositary which will then issue AstraZeneca DIs on a one-for-one basis in respect of such Affiliate Shares to the CREST account nominated by the relevant Affiliate Shareholder), in order to facilitate transfers of such Affiliate Shares through the CREST settlement system; or (iii) the DTC participant account of Euroclear Bank SA/NV, in order to facilitate transfers of such AstraZeneca Shares on Euroclear Sweden.

**(e)

AstraZeneca Shares represented by AstraZeneca ADSs**

The changes summarized in paragraphs (a), (b) and (c) above will not apply to AstraZeneca Shares in issue immediately prior to the implementation of the Harmonised Listing Structure that are held by Guaranty Nominees Limited, as nominee for the ADR Depositary. Instead, at the Effective Time, the existing AstraZeneca ADR facility arrangements will be terminated, any book entry interests held by the relevant DTC participants in the AstraZeneca ADSs will be debited (without further crediting), any AstraZeneca ADSs that remain issued and outstanding thereunder will be cancelled and legal title to the AstraZeneca Shares (other than Affiliate Shares) represented by such AstraZeneca ADSs prior to the Effective Time will be transferred in accordance with Articles 149.6,