Company: TAK
Filing Date: 2025-06-25
Form Type: F-3ASR
Source: 0001395064-25-000097
Chunk: 49

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-06-25
Form: F-3ASR
Chunk 49
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| 23.1           |     | Consent of KPMG AZSA LLC.                                                                                                                                                                                                                                                                     |
| 23.2           |     | Consent of Sullivan & Cromwell LLP (included in Exhibit 5.1).                                                                                                                                                                                                                                 |
| 23.3           |     | Consent of Nishimura & Asahi (Gaikokuho Kyodo Jigyo) (included in Exhibit 5.2).                                                                                                                                                                                                               |
| 24.1           |     | Power of Attorney of Takeda Pharmaceutical Company Limited and its authorized representative in the United States (included as part of the signature pages hereto).                                                                                                                           |
| 24.2           |     | Power of Attorney of Takeda U.S. Financing, Inc. (included as part of the signature pages hereto).                                                                                                                                                                                            |
| 25.1           |     | Form T-1 Statement of Eligibility under the Trust Indenture Act of 1939, as amended, of The Bank of New York Mellon, as trustee under the Indenture mentioned in Exhibit 4.1.                                                                                                                 |
| 25.2           |     | Form T-1 Statement of Eligibility under the Trust Indenture Act of 1939, as amended, of The Bank of New York Mellon, as trustee under the Indenture mentioned in Exhibit 4.2.                                                                                                                 |
| 107            |     | Filing Fee Table                                                                                                                                                                                                                                                                              |

_________________

* To be filed, if necessary, by amendment or as an exhibit to a report filed or submitted pursuant to Section 13(a) or 15(d) of the Exchange Act and incorporated by reference herein.

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### SIGNATURES OF TAKEDA PHARMACEUTICAL COMPANY LIMITED
Pursuant to the requirements of the Securities Act of 1933, as amended, Takeda Pharmaceutical Company Limited certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form F-3 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the city of Tokyo, Japan, on June 25, 2025.

| Takeda Pharmaceutical Company Limited |     |                   |     |                                      |
| By:                                   |     | /s/ Milano Furuta |     |                                      |
|                                       |     | Name:             |     | Milano Furuta                        |
|