Company: BDRX
Filing Date: 2025-01-17
Form Type: F-1
Source: 0001214659-25-000922
Chunk: 111

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-01-17
Form: F-1
Chunk 111
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 would permit the making of a valid QEF election, such an election will not be available to United States
holders.

Changes to U.S. and non-U.S. tax laws could materially adversely affect our Company and holders of our Ordinary Shares and the Depositary Shares.

The Tax Cuts and Jobs Act,
which was legislation bringing about broad changes in the existing U.S. corporate tax system, was enacted in the United States in December
2017. The Tax Cuts and Jobs Act made significant changes to the U.S. federal income tax laws. Certain provisions of the Tax Cuts and Jobs
Act could have an adverse effect on the Company or holders of our Ordinary Shares or Depositary Shares. The U.S. Treasury Department and
the IRS continue to interpret and issue guidance on how provisions of the Tax Cuts and Jobs Act will be applied and administered. The
interpretations of many provisions of the Tax Cuts and Jobs Act are still unclear. We cannot predict when or to what extent any additional
U.S. federal tax laws, regulations, interpretations, or rulings clarifying the Tax Cuts and Jobs Act will be issued or the impact of any
such guidance on investors or the Company. Holders of Ordinary Shares and Depositary Shares are urged to consult their own tax advisors
regarding the effect of the Tax Cuts and Jobs Act and other potential changes to the U.S. federal tax laws.

We are unable to predict what
tax changes may be enacted in the future or what effect such changes would have on our business, but such changes could affect our effective
tax rates in countries where we have operations and could have an adverse effect on our overall tax position in the future, along with
increasing the complexity, burden and cost of tax compliance. In addition, such changes could impact the holders of Ordinary Shares or
Depositary Shares.

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<div align='center'>CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS</div>

This prospectus contains certain
forward-looking information about the Company that is intended to be covered by the safe harbor for “forward-looking statements”
provided by the Private Securities Litigation Reform Act of 1995. These statements may be made directly in this prospectus or may be incorporated
into this prospectus by reference to other documents. Our representatives may also make forward-looking statements. Forward-looking statements
are statements that are not historical facts. Words such as “expect,” “believe,” “will,” “may,”
“anticipate,” “plan