Company: TELO
Filing Date: 2025-08-14
Form Type: 10-Q
Source: 0001641172-25-023970
Chunk: 4

Company: Telomir Pharmaceuticals, Inc.
Filing Date: 2025-08-14
Form: 10-Q
Item: Item 1
Chunk 4
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 also plays a critical role in the propagation and severity of viral
infections like bird flu, where the virus triggers an imbalance between increased production of reactive oxygen species (ROS) and reduced
antioxidant host responses that leads to increased redox stress, a process which ultimately excessive weakens immune defenses, increases
inflammation, and enables enhanced viral replication. By reversing oxidative stress, Telomir-1 may help strengthen immune resilience
and reduce disease severity, offering broad therapeutic potential across both age-related and infectious diseases. Telomeres are repetitive
DNA sequences at the end of chromosomes that protect the chromosomes from becoming frayed or tangled. Each time a cell divides, the telomeres
become slightly shorter, and eventually they become so short that the cell can no longer divide, with the result being that the cell
dies. Effectively, telomeres protect the ends of our chromosomes by forming a cap, much like the plastic tip on shoelaces, thereby allowing
the chromosome to be replaced properly during cell division. If demonstrated by future clinical trials and approved by the U.S. Food
and Drug Administration, or FDA, we believe Telomir-1 may protect variable cells by elongating and stimulating the telomeres to sustain
self-renewal and longevity. Based on our preclinical studies, we have gathered experimental evidence suggesting that Telomir-1 may act
as a regulator of essential metal ions such as iron, zinc, and copper. While these trace elements are critical for various physiological
functions, imbalances—whether due to excess or deficiency —can drive oxidative stress, leading to cellular damage, telomere
shortening, and accelerated aging. This oxidative burden is also linked to age-related conditions and certain cancers. We believe Telomir-1
has the potential to protect cells in situ by mitigating metal overload, particularly of iron and copper, which are known to accelerate
oxidative stress and contribute to telomere attrition. By modulating ion levels and reducing oxidative damage, Telomir-1 may help preserve
telomere integrity, restore cellular homeostasis, and enhance overall cell resilience, potentially slowing down age-related degeneration.
Additionally, by reversing oxidative stress, Telomir-1 may help mitigate the severity of viral infections such as bird flu by strengthening
cellular defense mechanisms and improving immune system function, potentially reducing disease progression and severity.

Basis
of presentation

The
accompanying unaudited condensed financial statements include the accounts