Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 352

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 352
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 traded on the NASDAQ stock exchange on the trading day preceding
the grant date.

<div align='center'>203</div>

53,694 options were granted
on March 16, 2020 to directors, employees, external consultants and advisors of the Group. One-half of each option grant vests on January
1, 2021 and expires on December 31, 2031 and the other half vests on January 1, 2022, and expires on December 31, 2032. The exercise price
is $29.9 per share, which was based on the average closing price of the shares traded on the NASDAQ stock exchange for the five trading
days immediately preceding the grant date.

14,896 options were granted
on June 1, 2020 to directors and employees of the Group. Nearly one-half of each option grant vests on December 1, 2020 and expires on
November 30, 2030 and the remaining vests on January 1, 2021 and expires on December 31, 2031. The exercise price is US$31.1 per share,
which was based on the average closing price of the shares traded on the NASDAQ stock exchange for the five trading days immediately preceding
the grant date.

2,748 options were granted
on August 10, 2020 to Dr. Weiss, which will be vested on August 10, 2021 and expires on August 9, 2032. The exercise price is $36.4 per
share, which was based on the average closing price of the shares traded on the NASDAQ stock exchange for the five trading days immediately
preceding the grant date.

75,235 options were granted
on March 11, 2021 to directors, employees, external consultants and advisors of the Group with an exercise price of $27.6 per share, which
was based on the average closing price of the shares traded on the NASDAQ stock exchange for the five trading days immediately preceding
the grant date.36,796 options vest on January 1, 2022, and expire on December 31, 2032; 36,808 options vest on January 1,
2023 and expire on December 31, 2033; 906 options vest on June 8, 2021 and expire on June 7, 2032; and 725 options vest on July 14, 2021
and expire on July 13, 203