Company: APM
Filing Date: 2025-10-14
Form Type: 424B5
Source: 0001213900-25-098635
Chunk: 99

Company: Aptorum Group Ltd
Filing Date: 2025-10-14
Form: 424B5
Chunk 99
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 unit agents and any
of their agents may treat the registered holder of any unit certificate as an absolute owner of the units evidenced by that certificate
for any purpose and as the person entitled to exercise the rights attaching to the units so requested, despite any notice to the contrary.

<div align='center'>16

Description of Debt Securities</div>

The following description,
together with the additional information we include in any applicable prospectus supplements, summarizes the material terms and provisions
of the debt securities that we may offer under this prospectus. While the terms we have summarized below will generally apply to any future
debt securities we may offer under this prospectus, we will describe the particular terms of any debt securities that we may offer in
more detail in the applicable prospectus supplement. The terms of any debt securities we offer under a prospectus supplement may differ
from the terms we describe below. As of the date of this prospectus, we have no outstanding registered debt securities.

We may issue notes under senior
or subordinated indentures or, separately, without the use of an indenture. If we issue senior or subordinated notes without the use of
an indenture, we will issue such senior or subordinated notes directly to the purchasers of such senior or subordinated notes.

If we issue senior notes under
a senior indenture, we will enter into such subordinated indenture with the trustee to be named in such senior indenture. If we issue
subordinated notes under a subordinated indenture, we will enter into such subordinated indenture with the trustee to be named in such
subordinated indenture. We will file as exhibits to the registration statement of which this prospectus is a part, or will incorporate
by reference from another report that we file with the SEC, the form of such notes and indentures, if any, that describes the terms of
the particular note we may offer under this prospectus, and any supplement agreements, before the issuance of the related note. We use
the term “indentures” to refer to both the senior indenture and the subordinated indenture.

The indentures will be qualified
under the Trust Indenture Act of 1939. References to the Trust Indenture Act of 1939 include all amendments thereto. We use the term “debenture
trustee” to refer to either the senior trustee or the subordinated trustee, as applicable.

The following summaries of
material provisions of the senior notes, the subordinated notes and