Company: BDRX
Filing Date: 2025-05-12
Form Type: 424B3
Source: 0001214659-25-007342
Chunk: 83

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-05-12
Form: 424B3
Chunk 83
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, a transaction fee
per cancellation request (including any cancellation request made through SWIFT, facsimile transmission or any other method of communication),
applicable delivery expenses or other such fees, charges or expenses), or otherwise prejudices any substantial existing right of ADR holders
or beneficial owners. Such notice need not describe in detail the specific amendments effectuated thereby, but must identify to ADR holders
and beneficial owners a means to access the text of such amendment. If an ADR holder or beneficial owner continues to hold an ADR or ADRs,
or an interest therein, after being so notified, such ADR holder and any beneficial owner are deemed to agree to such amendment and to
be bound by the Deposit Agreement as so amended. No amendment, however, will impair your right to surrender your Depositary Shares and
receive the underlying securities, except in order to comply with mandatory provisions of applicable law.

| 58 |

Any
amendments or supplements that (i) are reasonably necessary (as agreed by us and the depositary) in order for (a) the Depositary Shares
to be registered on Form F-6 under the Securities Act or (b) the Depositary Shares or Ordinary Shares to be traded solely in electronic
book-entry form and (ii) do not in either such case impose or increase any fees or charges to be borne by ADR holders, shall be deemed
not to prejudice any substantial rights of ADR holders or beneficial owners. Notwithstanding the foregoing, if any governmental body or
regulatory body should adopt new laws, rules or regulations that would require amendment or supplement of the Deposit Agreement or the
form of ADR to ensure compliance therewith, we and the depositary may amend or supplement the Deposit Agreement and the form of ADR (and
all outstanding ADRs) at any time in accordance with such changed laws, rules or regulations. Such amendment or supplement to the Deposit
Agreement in such circumstances may become effective before a notice of such amendment or supplement is given to ADR holders or within
any other period of time as required for compliance.

Notice of any amendment to
the Deposit Agreement or form of ADRs shall not need to describe in detail the specific amendments effectuated thereby, and failure to
describe the specific amendments in any such notice shall not render such notice invalid, provided, however, that, in each such case,
the notice given to the ADR holders identifies a means for ADR holders and beneficial owners to retrieve or receive the text of