Company: PFSA
Filing Date: 2025-04-03
Form Type: S-4/A
Source: 0001213900-25-028544
Chunk: 294

Company: Profusa, Inc.
Filing Date: 2025-04-03
Form: S-4/A
Chunk 294
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 | ) |     | 21.31 |     | 109.51 |     | 210.23 |     | 349.29 |     |   485.71 |   |     |   574.76 |   |     |   627.58 |     |   658.96 |
| Capital Expenditure         |     |   0.00 |   |     |  0.00 |   |     |  0.00 |     |   0.00 |     |   0.00 |     |   0.00 |     |     0.00 |   |     |     0.00 |   |     |     0.00 |     |     0.00 |
| Net Cash Flow               |     | (10.49 | ) |     | (9.71 | ) |     | 21.31 |     | 109.51 |     | 210.23 |     | 349.29 |     |   485.71 |   |     |   574.76 |   |     |   627.58 |     |   658.96 |

Non-GAAP Financial Measures In addition to the United States generally accepted accounting principles, or GAAP, results provided throughout this document, we have provided certain non -GAAPfinancial measures to help evaluate the results of our performance. We believe that these non -GAAPfinancial measures, when presented in conjunction with comparable GAAP financial measures, are useful to both management and investors in analyzing our ongoing business and operating performance. We believe that providing the non -GAAPinformation to investors, in addition to the GAAP presentation, allows investors to view our financial results in the way that management views financial results. The following table is a reconciliation from net loss, the most directly comparable financial measure calculated and presented in accordance with GAAP, to EBITDA and net cash flow presented in the Updated Projections:

| $ in millions                  |     |  2025E |   |     | 2026E |   |     | 2027E |     |  2028E |     |  2029E |     |  2030E |     |  2031E |   |     |  2032E |   |     |  2033E |     |  2034E |
| Net Loss                       |     | (10.