Company: PSTV
Filing Date: 2025-06-09
Form Type: DRS
Source: 0000950123-25-005986
Chunk: 22

Company: PLUS THERAPEUTICS, INC.
Filing Date: 2025-06-09
Form: DRS
Chunk 22
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 stock to Lincoln Park pursuant to the Purchase Agreement, we may need to sell to Lincoln Park more shares of our common stock than are offered under this prospectus in order to receive aggregate gross proceeds equal
to the approximately $[ ] million remaining balance of the $[ ] million total commitment available to us under the Purchase Agreement. If we choose to do so, we must again register for resale under the Securities Act such additional
shares of our common stock, which could cause additional substantial dilution to our stockholders. The number of shares ultimately offered for resale by Lincoln Park under this prospectus is dependent upon the number of shares we direct Lincoln Park
to purchase under the Purchase Agreement. We will not sell shares in excess of 19.99% of our outstanding shares as of the date we entered into the Purchase Agreement, until we obtain stockholder approval.

11

Confidential Treatment Requested by Plus Therapeutics, Inc. Pursuant to 17 C.F.R. Section 200.83 We have filed the registration statement that includes this prospectus so that we may issue to Lincoln Park up to 15,000,000 shares of our common stock from time to time from and after the date of this prospectus through sales under the Purchase Agreement. The following table sets forth the amount of gross proceeds we may receive from Lincoln Park from our sale of up to 15,000,000 shares of our common stock that we may issue and sell to Lincoln Park in the future under the Purchase Agreement assuming that all such common stock is sold at varying purchase prices designated below:

| Assumed Average Purchase 
 Price Per Share          |     | Number of shares to be 
 Issued if Full         
 Purchase(1)            |            |     | Percentage of Outstanding 
 Shares of Common          
 Stock After               
 Giving Effect to          
 the Sales to              
 Lincoln Park(2)           |   |    |     | Gross Proceeds from 
 the Future          
 Sale of Shares to   
 Lincoln Park        
 Under the Purchase  
 Agreement(1)        |   |   |
|:-------------------------|:----|:-----------------------|-----------:|:----|:--------------------------|:--|:---|:----|:--------------------|:--|:--|
| $[ ]                     |     |                        | 15,000,000 |     |                           | [ | ]% |     | $                   | [ | ] |
| $[ ](3)                  |     |                        | 15,000,000 |     |