Company: TVRD
Filing Date: 2025-01-21
Form Type: 425
Source: 0001104659-25-004749
Chunk: 3

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-01-21
Form: 425
Chunk 3
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 in the Solicitation

The Company and Tvardi, and
each of their respective directors and executive officers and certain of their other members of management and employees, may be deemed
to be participants in the solicitation of proxies in connection with the proposed transaction. Information about the Company’s directors
and executive officers, consisting of Helen M. Boudreau, Jeffrey L. Ives, Ph.D., Christopher Posner, Susan Shiff, Ph.D., Martin Vogelbaum,
Lisa von Moltke, M.D., Ryan Maynard and Scott Terrillion, including a description of their interests in the Company, by security holdings
or otherwise, can be found under the captions, “Security Ownership of Certain Beneficial Owners and Management,” “Executive
Compensation” and “Director Compensation” contained in the definitive proxy statement on Schedule 14A for the Company’s
2024 annual meeting of stockholders, filed with the SEC on April 22, 2024 (the “2024 Cara Proxy Statement”). To the extent
that the Company’s directors and executive officers and their respective affiliates have acquired or disposed of security holdings
since the applicable “as of” date disclosed in the 2024 Cara Proxy Statement, such transactions have been or will be reflected
on Statements of Change in Beneficial Ownership on Form 4 filed with the SEC. Additional information regarding the persons who may be
deemed participants in the proxy solicitation, including the information about the directors and executive officers of Tvardi, and a description
of their direct and indirect interests, by security holdings or otherwise, are also included in a registration statement filed on Form
S-4 that contains a preliminary proxy statement (and preliminary prospectus and other relevant materials) filed with the SEC. Investors
should read the registration statement, preliminary proxy statement/prospectus and the other relevant materials when they become available
before making any voting or investment decision with respect to the proposed transaction. These documents can be obtained free of charge
from the sources indicated above.

Non-Solicitation

This Current Report on Form
8-K shall not constitute an offer to sell or the solicitation of an offer to sell or the solicitation of an offer to buy any securities,
nor shall there be any sale of securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration
or qualification under the securities laws of any such jurisdiction. No public offer of securities shall be made except by means of a
prospectus meeting the requirements of Section