Company: INSP
Filing Date: 2025-03-18
Form Type: DEF 14A
Source: 0001140361-25-009249
Chunk: 1

Company: Inspire Medical Systems, Inc.
Filing Date: 2025-03-18
Form: DEF 14A
Chunk 1
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 to lead our organization in driving financial and operational excellence and creating long-term stakeholder value. |
| On behalf of the Board of Directors and management, it is my pleasure to express our appreciation for your continued support.                                                                                                            |
| Timothy P. Herbert                                                                                                                                                                                                                       
 Chairman, President & Chief Executive Officer                                                                                                                                                                                            |

TABLE OF CONTENTS

INSPIRE MEDICAL SYSTEMS, INC. 5500 WAYZATA BLVD., SUITE 1600 | GOLDEN VALLEY, MN 55416 NOTICE IS HEREBY GIVEN that the Annual Meeting of Stockholders of Inspire Medical Systems, Inc., a Delaware corporation, will be held on Thursday, May 1, 2025, at 9:00 a.m. Eastern Time. The Annual Meeting will be a completely virtual meeting, which will be conducted via live webcast. You will be able to attend the Annual Meeting online and submit your questions during the meeting by visiting www.virtualshareholdermeeting.com/INSP2025 . For instructions on how to attend and vote your shares at the Annual Meeting, see the information in the accompanying Proxy Statement in the section titled “General Information about the Annual Meeting and Voting — How can I attend and vote at the Annual Meeting?” The Annual Meeting is being held to:

| Votes Required |     | Board of       
 Directors      
 Recommendation |

| Proposal 1 |     | Elect Cynthia B. Burks, Timothy P. Herbert, and Shawn T McCormick as Class I directors to hold office until the Company’s annual meeting of stockholders to be held in 2028 and until their respective successors have been duly elected and qualified |     | A plurality of the votes cast. This means that the three nominees receiving the largest number of affirmative “FOR” votes will be elected as Class I directors                                        |     | FOR |
| Proposal 2 |     | Ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for 2025                                                                                                                                              |     | The affirmative vote of the holders of a majority in voting power of the votes cast affirmatively or negatively (excluding abstentions) at the Annual Meeting by the holders entitled to vote thereon |     | FOR |
| Proposal 3 |     | Approve, on an advisory (non-binding) basis, of the compensation of our named executive officers                                                                                                                                                       |     | The affirmative vote of the holders of a majority in voting power of the votes cast affirmatively or negatively (excluding abstentions) at the Annual Meeting by the holders entitled to vote thereon