Company: CRL
Filing Date: 2025-04-02
Form Type: DEF 14A
Source: 0001104659-25-030908
Chunk: 1

Company: CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
Filing Date: 2025-04-02
Form: DEF 14A
Chunk 1
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 the instructions set forth on the card. This will ensure your proper representation at the Annual Meeting.

| ​ | ​ | ​ | ​ | Sincerely,                                   | ​ |
| ​ | ​ | ​ | ​ |                                              | ​ |
| ​ | ​ | ​ | ​ | James C. Foster                              
 Chair, President and Chief Executive Officer | ​ |

YOUR VOTE IS IMPORTANT.
PLEASE VOTE YOUR SHARES PROMPTLY.

Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting of Shareholders to be held on May 20, 2025. This Proxy Statement and our Annual Report to Shareholders are available at www.criver.com/annual2025 . In addition, our Annual Report on Form 10-K for fiscal year 2024 can be found on the same website.

CHARLES RIVER LABORATORIES INTERNATIONAL, INC. NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
to Be Held on May 20, 2025 To the Shareholders of Charles River Laboratories International, Inc.: NOTICE IS HEREBY GIVEN that the Annual Meeting of Charles River Laboratories International, Inc., a Delaware corporation, will be held on Tuesday, May 20, 2025, at the offices of Cooley LLP located at 500 Boylston Street, Boston, MA 02116 at 8:00 a.m., for the following purposes: 1. To elect each of the eleven (11) persons named in this Proxy Statement to our Board of Directors to hold office until the next Annual Meeting of Shareholders. 2. To approve an advisory vote on our executive compensation. 3. To consider and act upon a proposal to ratify the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the fiscal year ending December 27, 2025. 4. To vote on a shareholder proposal described in this Proxy Statement, if properly presented at the Annual Meeting. 5. To transact such other business as may be properly brought before the Annual Meeting and any adjournments thereof. The Board of Directors has fixed the close of business on March 21, 2025 as the record date for the determination of shareholders entitled to notice of, and to vote at, the Annual Meeting and at any adjournments thereof. All shareholders are cordially invited to attend the Annual Meeting. Attendance at the Annual Meeting will be limited to shareholders and those holding proxies from shareholders. An admission ticket and government-issued picture identification will be required to enter the Annual