Company: XXII
Filing Date: 2025-08-26
Form Type: 424B5
Source: 0001641172-25-025541
Chunk: 2

Company: 22nd Century Group, Inc.
Filing Date: 2025-08-26
Form: 424B5
Chunk 2
---
 factors you should consider before investing in our securities.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

There is no arrangement for funds to be received in escrow, trust or similar arrangement.

|                                     |     | Per share of Common Stock Underlying 
 the Series A                         
 Preferred Stock and                  
 Accompanying                         
 Warrant                              |        |     | Total |            |
|:------------------------------------|:----|:-------------------------------------|-------:|:----|:------|-----------:|
| Offering price                      |     | $                                    |   2.19 |     | $     | 10,650,000 |
| Placement Agent Fees(1)             |     | $                                    | 0.1314 |     | $     |    639,000 |
| Proceeds, before expenses, to us(2) |     | $                                    | 2.0586 |     | $     | 10,011,000 |

(1) We estimate the total expenses of this offering, excluding the placement agent fees and expenses, will be approximately $125,000. We will pay the placement agent a cash fee equal to six percent (6%) of the aggregate gross proceeds raised in this offering. In addition, we have agreed to pay the placement agent a cash fee equal to six percent (6%) of the aggregate cash exercise price, if any, received by us upon exercise of Warrants issued in connection with this offering that were solicited by the placement agent. We will also reimburse the placement agent for its expenses, including the reimbursement of legal fees in an amount not to exceed $25,000. In addition, we have agreed to issue the placement agent or its designees warrants to purchase up to 567,641 shares of common stock (equal to 6% of the aggregate number of shares of common stock sold in this offering) at an exercise price of $2.167 (the “placement agent warrants”). See “Plan of Distribution” for a complete description of the compensation to be received by the placement agent.

(2) The amount of the offering proceeds to us presented in this table does not give effect to any exercise of the warrants being issued in this offering.

We are a “smaller reporting company” under the federal securities laws and, as such, we have elected to comply with certain reduced public company reporting requirements and scaled disclosures for this