Company: APM
Filing Date: 2025-01-03
Form Type: 424B5
Source: 0001213900-25-000606
Chunk: 16

Company: Aptorum Group Ltd
Filing Date: 2025-01-03
Form: 424B5
Chunk 16
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 as a result of this offering:

| Assumed offering price per share                                                                         |     |   |       |   |     | $ |  2.00 |   |
| Net tangible book value per share as of June 30, 2024                                                    |     | $ |  2.35 |   |     | $ |       |   |
| Decrease in net tangible book value per share to existing investors after giving effect to this offering |     | $ | (0.13 | ) |     |   |       |   |
| As adjusted net tangible book value per share as of June 30, 2024, after giving effect to this offering  |     |   |       |   |     | $ |  2.22 |   |
| Dilution in net tangible book value per share to new investors in this offering                          |     |   |       |   |     | $ | (0.22 | ) |

The above discussion and table
are based on 3,674,164 Class A Ordinary Shares and 1,796,934 Class B Ordinary Shares outstanding as of June 30, 2024 and exclude:

| ● | 294,224 Class A Ordinary Shares issuable to investors, Wainwright and the placement agent in the registered direct offering closed on February 28, 2020, upon exercise of the warrants issued on October 2, 2020; |
| ● | 54,054 Class A Ordinary Shares issuable to Jurchen, the largest shareholder of the Company, upon exercise of warrants issued on February 28, 2020; and                                                            |
| ● | 1,301,033 Class A Ordinary Shares issuable to Jurchen upon exercise of convertible bonds issued on September 11, 2023.                                                                                            |

To the extent that any of
our outstanding options or warrants are exercised, we grant additional options or other awards under our share incentive plan or issue
additional warrants, or we issue additional ordinary shares in the future, there may be further dilution.

<div align='center'>S-9

DESCRIPTION OF OUR SECURITIES WE ARE OFFERING</div>

We are offering 1,535,000
Class A Ordinary Shares for an aggregate value of $3,070,000 pursuant to this prospectus supplement and the accompanying prospectus. The
material terms and provisions of our ordinary shares are described under the caption “Description of Share Capital” beginning
on page 7 of the accompanying prospect