Company: MDCXW
Filing Date: 2025-03-28
Form Type: 253G2
Source: 0001062993-25-006502
Chunk: 41

Company: Medicus Pharma Ltd.
Filing Date: 2025-03-28
Form: 253G2
Chunk 41
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 Pittsburgh will grant any necessary future extensions to milestone requirements commensurate with our progress with its clinical development plan. We have licensed three patent families from the University of Pittsburgh that include several granted U.S. patents and pending U.S. patent applications, as well as granted patents and pending patent applications in foreign jurisdictions, relating to microneedle arrays for delivering various drugs and bioactive agents to the skin, their use, and manufacture. The first patent family entitled "dissolvable microneedle arrays for transdermal delivery to human skin" includes 2 issued U.S. patents expiring in 2030 and 2031 claiming dissolvable microneedle arrays including a variety of bioactive components. This family also includes a pending U.S application. The second patent family entitled "Tip loaded microneedle arrays for transdermal insertion" includes 1 issued U.S. patent expiring in 2033 claiming dissolvable microneedle arrays including one or more bioactive components. This family also includes issued patents in Australia, Canada, Japan and Mexico, and pending applications in the U.S., Australia, Europe, Hong Kong, India, Japan, and Mexico. The third patent family entitled "Microneedle arrays for cancer therapy applications" includes a pending U.S. patent application as well as pending patent applications in Australia, Canada, Europe, Israel, Japan, and Korea relating to the use of microneedle arrays comprising one or more bioactive agents for the treatment of various cancers, which if issued, would have a natural expiration in 2035. The table below summarizes the patents covered by the License Agreement, each of which is a utility patent. 36

| Country Name  |     | Title                                                                 |     |      Application 
              No. |     | Priority Date |     | Filed Date |     | Patent No. |     | Issue Date |     | Projected  
 Expiration 
 Date       |     | Status  |     | Assignee(s)                                                                                        |
| United States |     | Dissolvable microneedle arrays for transdermal delivery to human skin |     |       12/910,516 |     | 10/23/2009    |     | 10/22/2010 |     |  8,834,423 |     | 9/16/2014  |     | 6/14/2031  |     | Issued  |     | University Of Pittsburgh of The Commonwealth System of Higher Education/C