Company: SCLXW
Filing Date: 2025-02-14
Form Type: PRE 14A
Source: 0001193125-25-027244
Chunk: 0

Company: Scilex Holding Co
Filing Date: 2025-02-14
Form: PRE 14A
Chunk 0
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PRELIMINARY COPY DATED FEBRUARY 14, 2025 — SUBJECT TO COMPLETION UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box:

| ☒ | Preliminary Proxy Statement |

| ☐ | Confidential, for Use of the Commission Only (as permitted by Rule 
 14a-6(e)(2))                                                       |

| ☐ | Definitive Proxy Statement |

| ☐ | Definitive Additional Materials |

| ☐ | Soliciting Material under §240.14a-12 |

SCILEX HOLDING COMPANY (Name of Registrant as Specified in Its Charter) N/A (Name of Person(s) Filing Proxy Statement, if other than the Registrant) Payment of Filing Fee (Check all boxes that apply):

| ☒ | No fee required. |

| ☐ | Fee paid previously with preliminary materials. |

| ☐ | Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11. |

PRELIMINARY COPY DATED FEBRUARY 14, 2025 — SUBJECT TO COMPLETION SCILEX HOLDING COMPANY 960 San Antonio Road Palo Alto, CA 94303 NOTICE OF SPECIAL MEETING OF STOCKHOLDERS To Be Held at 9:00 a.m. Pacific Time on Wednesday, March 19, 2025 Dear Stockholders of Scilex Holding Company: We cordially invite you to attend a special meeting of stockholders (the “Special Meeting”) of Scilex Holding Company, a Delaware corporation (the “Company”, “Scilex”, “we”, “us” or “our”), which will be held virtually on Wednesday, March 19, 2025 at 9:00 a.m. Pacific Time via live audio webcast on the Internet at www.virtualshareholdermeeting.com/SCLX2025SMfor the following purposes, as more fully described in the accompanying proxy statement for the Special Meeting (the “Proxy Statement”):

| 1. | To approve any amendment to the Company’s Restated Certificate of Incorporation to effect a reverse                                                                                                                                   
 stock split of the Company