Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 256

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 256
---
 transfer by the corporation of 
 any stock of the corporation to the interested stockholder;                                           |

| ● | subject to exceptions, any transaction involving the corporation that has the effect of increasing the                           
 proportionate share of the stock of any class or series of the corporation beneficially owned by the interested stockholder; and |

| ● | the receipt by the interested stockholder of the benefit of any loans, advances, guarantees, pledges or 
 other financial benefits provided by or through the corporation.                                        |

In general, Section 203
defines an interested stockholder as any entity or person beneficially owning 15% or more of the outstanding voting stock of the corporation
and any entity or person affiliated with or controlling or controlled by the entity or person.

<div align='center'>151</div>

Certificate of Incorporation and Bylaw Provisions

Our amended and restated certificate
of incorporation and our bylaws include a number of provisions that may have the effect of deterring hostile takeovers, or delaying or
preventing changes in control of our management team or changes in our board of directors or our governance or policy, including the following:

Board Vacancies

Our amended and restated certificate
of incorporation and bylaws authorize generally only our board of directors to fill vacant directorships resulting from any cause or created
by the expansion of our board of directors. In addition, the number of directors constituting our board of directors may be set only by
resolution adopted by a majority vote of our entire board of directors. These provisions prevent a stockholder from increasing the size
of our board of directors and gaining control of our board of directors by filling the resulting vacancies with its own nominees.

Classified Board

Our amended and restated certificate
of incorporation and bylaws will provide that its board of directors is classified into three classes of directors. The existence of a
classified board of directors could delay a successful tender offeror from obtaining majority control of our board of directors, and the
prospect of that delay might deter a potential offeror.

Directors Removed Only for Cause

Our amended and restated certificate
of incorporation will provide that stockholders may remove directors only for cause.

Supermajority Requirements for Amendments of Our Amended and Restated Certificate of Incorporation and Bylaws

Our amended and restated certificate
of incorporation further provides that the affirmative vote of holders of at least 75% of the voting power of our outstanding common stock
is required to amend certain provisions of our amended and restated certificate of incorporation, including provisions