Company: NCEL
Filing Date: 2025-10-17
Form Type: POS AM
Source: 0001213900-25-099986
Chunk: 3

Company: NewcelX Ltd.
Filing Date: 2025-10-17
Form: POS AM
Chunk 3
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 to purchase NLS Common Shares. This prospectus supplement, or the Supplement, includes (i) NLS’s Unaudited Interim Condensed Financial Statements as of June 30, 2025 and December 31, 2024 and for the six months ended June 30, 2025 and 2024; (ii) the NLS’s Management’s Discussion and Analysis of Financial Condition and Results of Operations for the six months ended June 30, 2025; (iii) Kadimastem Ltd.’s, an Israeli publicly traded company limited by shares (TASE: KDST), or Kadimastem, Interim Condensed Financial Statements as of and for the six months ended June 30, 2025; (iv) Kadimastem’s Audited Financial Statements as of and for the years ended December 31, 2024 and 2023; and (v) NLS’s Unaudited Pro Forma Condensed Combined Financial Statements as of and for the six months ended June 30, 2025. Updates the information contained in the Prospectus and should be read together with the information in the Prospectus. The updates contained in this Supplement supersede any conflicting information contained in the Prospectus. The NLS Common Shares are listed on the Nasdaq Capital Market, or Nasdaq, under the symbol “NLSP”. On October 16, 2025, the last reported sale price of the NLS Common Shares on Nasdaq was $1.63. Neither the U.S. Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense. Investing in NLS Common Shares involves risks. See “Risk Factors” beginning on page 25 in the Prospectus. The date of this Supplement to Proxy Statement/Prospectus is, 2025.

TABLE OF CONTENTS

| RECENT DEVELOPMENTS                                                                                                                                           
 NLS’S MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS FOR THE SIX MONTHS ENDED JUNE 30, 2025                            
 KADIMASTEM’S MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS FOR THE SIX MONTHS ENDED JUNE 30, 2025                     |     | Page 
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