Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 37

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 37
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Union have each imposed export controls on certain products and financial and economic sanctions on certain industry sectors and parties
in Russia. Although we have no operations in Russia or Ukraine, we may experience shortages in materials and increased costs for transportation,
energy, and raw materials due in part to the negative impact of the Russia-Ukraine military conflict on the global economy. The scope
and duration of the military conflict in Ukraine is uncertain, rapidly changing and hard to predict. Further escalation of geopolitical
tensions related to the military conflict, including increased trade barriers or restrictions on global trade, could result in, among
other things, cyberattacks, supply disruptions, lower consumer demand, and changes to foreign exchange rates and financial markets, any
of which may adversely affect our business and supply chain.

We may face risks associated with acquisitions of companies, products and technologies and our business could be harmed if we are unable to address these risks.

We may in the future
seek to acquire or invest in businesses, applications or technologies that we believe could complement or expand our portfolio,
enhance our technical capabilities or otherwise offer growth opportunities. However, we cannot assure you that we would be able to
successfully complete any acquisition we choose to pursue, or that we would be able to successfully integrate any acquired business,
product or technology in a cost-effective and non-disruptive manner. The pursuit of potential acquisitions may divert the attention
of management and cause us to incur various costs and expenses in identifying, investigating and pursuing suitable acquisitions,
whether or not they are consummated. We may not be able to identify desirable acquisition targets or be successful in entering into
an agreement with any particular target or obtain the expected benefits of any acquisition or investment.

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To date, the growth of our
operations has been largely organic, and we have limited experience in acquiring other businesses or technologies. We may not be able
to successfully integrate any acquired personnel, operations and technologies, or effectively manage the combined business following an
acquisition. Acquisitions could also result in dilutive issuances of equity securities, the use of our available cash, or the incurrence
of debt, which could harm our operating results. In addition, if an acquired business fails to meet our expectations, our operating results,
business and financial condition may suffer.

Our success will depend on our ability to attract and retain our personnel and manage our human capital, while controlling labor costs.

Our future success depends
on our ability to attract, recruit, train, retain, motivate and