Company: BLLN
Filing Date: 2025-10-07
Form Type: S-1
Source: 0001193125-25-233697
Chunk: 266

Company: BillionToOne, Inc.
Filing Date: 2025-10-07
Form: S-1
Chunk 266
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of the directors. This classification of the Board may have the effect of delaying or preventing changes in our control or management. Once our Class B common stock no longer represents a majority of voting power of our outstanding capital stock, no member of our Board may be removed from office by our stockholders except for cause by the affirmative vote of two-thirdsof the voting power of our then-outstanding capital stock. Our directors were elected to and currently serve on the Board of Directors pursuant to the Voting Agreement. See the section titled “Certain relationships and related party transactions—Voting agreement.” This agreement will terminate upon the completion of this offering, after which there will be no further contractual obligations regarding the election of our directors. Following this offering, pursuant to the listing standards of Nasdaq, our director nominees must either be selected, or recommended for the Board’s selection, by independent directors constituting a majority of the Board’s independent directors in a vote in which only independent directors participate. Director independence Our Board of Directors has undertaken a review of the independence of the directors and considered whether any director has a material relationship with us that could compromise his or her ability to exercise 199

independent judgment in carrying out his or her responsibilities. Based upon information requested from and provided by each director concerning such director’s background, employment and
affiliations, including family relationships, our Board of Directors determined that Thomas Bremner, Krishna Swaroop Kolluri, Firat Ileri, and Akshay Rai representing four of our six directors, are “independent directors” as defined
under current rules and regulations of the SEC and the listing standards of the Nasdaq Global Select Market (Nasdaq). In making these determinations, our Board considered the current and prior relationships that each
non-employee director has with our company and all other facts and circumstances that our Board deemed relevant in determining their independence, including the beneficial ownership of our capital stock by
each non-employee director and the transactions involving them described in “Certain relationships and related party transactions.”

Board leadership structure

Our Board of Directors is currently chaired by
our Chief Executive Officer and Co-Founder, Dr. Atay. Our Board of Directors does not have a policy that requires the roles of Chief Executive Officer and Chairman of the Board to be separate. The Board
believes that Mr. Atay’s service as both Chief Executive Officer and Chairman of the Board is in the best interest of us and our stockholders.

Our
corporate governance guidelines, which will be in effect upon