Company: HURA
Filing Date: 2025-11-03
Form Type: S-3
Source: 0001193125-25-262843
Chunk: 16

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-11-03
Form: S-3
Chunk 16
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     | evidence and provide for successor trustees; |

| • |     | add, change or eliminate any provision affecting registration as to principal of debt securities; |

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| • |     | permit the exchange of debt securities; |

| • |     | change or eliminate restrictions on payment in respect of debt securities; |

| • |     | change or eliminate provisions or add any other provisions that are required or desirable in accordance with any                                                                                                       
 amendments to the Trust Indenture Act, on the condition that this action does not adversely affect the interests of any holder of debt securities of any series issued under the indenture in any material respect; or |

| • |     | cure any ambiguity or correct any mistake. |

In addition, with the consent of the holders of not less than a majority in aggregate principal amount of the outstanding debt securities of all series affected by the supplemental indenture, we and the trustee may execute supplemental indentures adding any provisions to or changing or eliminating any of the provisions of the applicable indenture or any supplemental indenture or modifying the rights of the holders of debt securities of that series. No such supplemental indenture may, however, without the consent of the holder of each debt security that is affected:

| • |     | change the time for payment of principal or interest on any debt security; |

| • |     | reduce the principal of, or any installment of principal of, or interest on, any debt security; |

| • |     | reduce the amount of premium, if any, payable upon the redemption of any debt security; |

| • |     | reduce the amount of principal payable upon acceleration of the maturity of an original issue discount debt 
 security;                                                                                                   |

| • |     | impair the right to institute suit for the enforcement of any payment on or for any debt security; |

| • |     | reduce the percentage in principal amount of the outstanding debt securities of any series the consent of whose                                                            
 holders is required for modification or amendment of the indenture or for waiver of compliance with certain provisions of the indenture or for waiver of certain defaults; |

| • |     | modify the provisions relating to waiver of some defaults or any of the foregoing provisions; |

| • |     | change the currency of payment; |

| • |     | adversely affect the right to repayment of debt securities of any series at the option of the holders of those 
 debt securities; or                                                                                            |

| • |     | change the place of payment. |

Any supplemental indenture will be