Company: GLPG
Filing Date: 2025-03-27
Form Type: 20-F
Source: 0001558370-25-003806
Chunk: 168

Company: GALAPAGOS NV
Filing Date: 2025-03-27
Form: 20-F
Item: Item 4
Chunk 168
---
 condition or cash flows. Regardless of the outcome, litigation can have an adverse impact on us because of defense and settlement costs, diversion of management resources and other factors.
​

​
118

Glossary of terms
Glossary of terms, to be read only in conjunction with this annual report.
​

Term                             Description                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
ADS                              American Depositary Share; Galapagos has a Level 3 ADS listed on Nasdaq with ticker symbol GLPG and CUSIP number 36315X101. One ADS is equivalent to one ordinary share in Galapagos NV                                                                                                                                                                                                                                                                                                                                                                                                                                                            
Antibody                         A blood protein produced in response to and counteracting a specific antigen. Antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances                                                                                                                                                                                                                                                                                                                                                                                                                                  
Antigen-binding fragment (Fab)   Region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain"                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
Assays                           Laboratory tests to determine characteristics                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
ATALANTA-1                       ATALANTA-1 Phase 1/2 study with decentralized manufactured CD19 CAR-T candidate, GLPG5101, in different aggressive B-cell malignancies                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
Auto-immune indication           Autoimmune diseases result when your immune system is overactive, causing it to attack and damage your body's own tissues. Normally, your immune system creates proteins called antibodies that work to protect you against harmful substances such as viruses, cancer cells, and toxins. But with autoimmune disorders, your immune system can't tell the difference between invaders and healthy cells                                                                                                                                                                                                                                           
BCMA                             B cell maturation antigen (BCMA) is a member of the tumor necrosis factor receptor superfamily that plays an important role in regulating B-cell proliferation and survival. BCMA is central to the survival of multiple myeloma cells                                                                                                                                                                                                                                                                                                                                                                                                             
Biologics                        Biologics, also referred to as Biologicals, are those class of medicines which are grown and then purified from large-scale cell cultures of bacteria or yeast, or plant or animal cells. Biologicals are a diverse group of medicines which includes vaccines, growth factors, immune modulators, monoclonal antibodies, as well as products derived from human blood and plasma. What distinguishes biologics from other medicines is that these are generally proteins purified from living culture systems or from blood, whereas other medicines are considered as