Company: CERO
Filing Date: 2025-11-17
Form Type: NT 10-Q
Source: 0001213900-25-111295
Chunk: 0

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-11-17
Form: NT 10-Q
Chunk 0
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<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 12b-25

NOTIFICATION OF LATE FILING</div>

| (Check One): |     | ☐                                                
 Form 10-K ☐ Form 20-F ☐                          
 Form 11-K ☒ Form 10-Q                            
 ☐                                                
 Form 10-D ☐ Form N-CEN ☐                         
 Form N-CSR                                       
 For Period Ended: September 30, 2025             |
|:-------------|:----|:-------------------------------------------------|
|              |     | ☐ Transition Report on Form 10-K                 |
|              |     | ☐ Transition Report on Form 20-F                 |
|              |     | ☐ Transition Report on Form 11-K                 |
|              |     | ☐ Transition Report on Form 10-Q                 |
|              |     | For the transition period ended: _______________ |

| Read Instruction (on back page) Before Preparing                   
 Form. Please Print or Type.                                        
 Nothing in this form shall be construed to imply                   
 that the Commission has verified any information contained herein. |

If the notification relates to a portion of the filing checked above,
identify the Item(s) to which the notification relates:

<div align='center'>PART I — REGISTRANT INFORMATION

CERo Therapeutics Holdings, Inc.

Full Name of Registrant

Former Name if Applicable

201 Haskins Way, Suite 230

Address of Principal Executive Office (Street and Number)

South San Francisco, CA, 94080

City, State and Zip Code

PART II — RULES 12b-25(b) AND (c)</div>

If the subject report could not be filed without unreasonable effort
or expense and the registrant seeks relief pursuant to Rule 12b-25(b), the following should be completed. (Check box if appropriate)

| ☒ |    | -a                                                                                                                                           | The reasons described in reasonable detail in                                         
 Part III of this form could not be eliminated without unreasonable effort or expense; |
|   | -b | The subject annual report, semi-annual report,                                                                                               
 transition report on Form 10-K, Form 20-F, Form 11-K, Form N-CEN or Form N-CSR, or portion thereof, will be filed on or before the fifteenth 
 calendar day following the prescribed due date; or the subject quarterly report or transition report