Company: BLTE
Filing Date: 2025-01-27
Form Type: 424B7
Source: 0001104659-25-006367
Chunk: 5

Company: BELITE BIO, INC
Filing Date: 2025-01-27
Form: 424B7
Chunk 5
---
 collaborations or licensing agreements;

•

our ability to identify and integrate new product candidates, technologies and/or suitable acquisition targets;

•

our ability to effectively manage our growth;

•

changes to regulatory and operating conditions in our industry and markets; and

•

the potential impact of COVID-19 and other epidemics on our current and future business development, financial condition and results of operations.

The “ Risk Factors ” section of this prospectus supplement, the accompanying prospectus, and our Annual Reports on Form 20-F and reports on Form 6-K filed with the SEC and incorporated by reference into this prospectus supplement or the accompanying prospectus discusses the principal contingencies and uncertainties to which we believe we are subject, which should be considered in evaluating any forward- looking statements contained or incorporated by reference in this prospectus supplement or in the accompanying prospectus.

<div align='center'>S-3</div>

TABLE OF CONTENTS

### PROSPECTUS SUPPLEMENT SUMMARY
This summary highlights selected information about us, this offering and information contained in greater detail elsewhere in this prospectus supplement, the accompanying prospectus, any free writing prospectus that we have authorized for use, and in the documents incorporated by reference. This summary is not complete and does not contain all of the information that you should consider before investing in our ADSs. You should carefully read and consider this entire prospectus supplement, the accompanying prospectus and the documents, including financial statements and related notes, and information incorporated by reference into this prospectus supplement, including the financial statements and “Risk Factors” starting on page S-10 of this prospectus supplement, before making an investment decision. If you invest in our securities, you are assuming a high degree of risk.

### Our Business

### Overview
We are a clinical stage biopharmaceutical drug development company focused on advancing novel therapeutics targeting retinal degenerative eye diseases which have significant unmet medical need such as (i) atrophic age-related macular degeneration, or AMD, commonly known as Geographic Atrophy, or GA, in advanced dry AMD, and (ii) autosomal recessive Stargardt disease type 1, or STGD1. Both GA and STGD1 cause progressive loss of vision leading to permanent blindness. In addition to our lead product candidate (Tinlarebant) which is intended for the treatment of GA and STGD1, our drug development pipeline also includes a small molecule, orally administered compound which is intended for the treatment of metabolic diseases such as non-alcoholic fatty liver