Company: SION
Filing Date: 2025-02-03
Form Type: S-1/A
Source: 0001193125-25-018825
Chunk: 229

Company: Sionna Therapeutics, Inc.
Filing Date: 2025-02-03
Form: S-1/A
Chunk 229
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 and that such losses can be reasonably estimated. Significant judgment by us is required to determine both probability and the estimated amount. Our management is currently not aware of any legal
matters that could have a material effect on our financial position, results of operations or cash flows.

168

MANAGEMENT Executive Officers, Key Employees and Directors The following table sets forth information regarding our executive officers, key employees and directors as of December 31, 2024.

| Name                            |     | Age |    |     | Position                                                  |
| Executive Officers:             |     |     |    |     |                                                           |
| Michael Cloonan, M.B.A.         |     |     | 53 |     | Chief Executive Officer, President and Director           |
| Charlotte McKee, M.D.           |     |     | 60 |     | Chief Medical Officer                                     |
| Elena Ridloff, C.F.A.           |     |     | 45 |     | Chief Financial Officer and Head of Corporate Development |
| Non-Employee Directors:         |     |     |    |     |                                                           |
| Paul Clancy, M.B.A.(2)(3)       |     |     | 63 |     | Chairperson of the Board                                  |
| Bruce Booth, D.Phil.(1)         |     |     | 50 |     | Director                                                  |
| H. Edward Fleming, Jr., M.D.(2) |     |     | 61 |     | Director                                                  |
| Lucian Iancovici, M.D.(1)       |     |     | 42 |     | Director                                                  |
| Joshua Resnick, M.D., M.B.A.    |     |     | 50 |     | Director                                                  |
| Marcella Kuhlman Ruddy, M.D.(3) |     |     | 62 |     | Director                                                  |
| Laurie Stelzer, M.B.A.(1)(2)    |     |     | 57 |     | Director                                                  |
| Peter A. Thompson, M.D.(3)      |     |     | 65 |     | Director                                                  |
| Joanne Louise Viney, Ph.D.(1)   |     |     | 59 |     | Director                                                  |

| (1) | Member of the compensation committee. |

| (2) | Member of the audit committee. |

| (3) | Member of the nominating and corporate governance committee. |

Executive Officers Michael Cloonan, M.B