Company: CERO
Filing Date: 2025-10-23
Form Type: 424B3
Source: 0001213900-25-101650
Chunk: 9

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-10-23
Form: 424B3
Chunk 9
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capital stock (other than as required under the Certificate of Designations) and will not incur any indebtedness other than ordinary course
trade payables or, subject to certain exceptions, incur any liens. In addition, the Company will not issue any preferred stock or issue
any other securities that would cause a breach or default under the Certificate of Designations.

Reservation Requirements. So long as any
Series E Preferred Stock remains outstanding, the Company shall at all times reserve at least 250% of the number of shares of Common Stock
as shall from time to time be necessary to effect the conversion of all Series E Preferred Stock then outstanding.

Registration Rights Agreement

On the First Closing Date, the Company will enter
into a registration rights agreement by and between the Company and the PIPE Investors (the “Registration Rights Agreement”),
pursuant to which the Company will be required to file a registration statement with the Securities and Exchange Commission (the “SEC”),
to register for resale the Common Stock issuable upon the conversion of the Series E Preferred Stock.

<div align='center'>3</div>

The foregoing description of the Private Placement
does not purport to be complete and is qualified in its entirety by reference to the Certificate of Designations, the Securities Purchase
Agreement, and the Registration Rights Agreement, which are filed as Exhibits 3.1, 10.1, and 10.2 to this Current Report on Form 8-K and
are incorporated by reference herein.

This Current Report on Form 8-K shall not constitute
an offer to sell or a solicitation of an offer to buy, nor shall there be any sale, of the Series E Preferred Stock in any state or jurisdiction
in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any
such state or other jurisdiction.

Item 3.02 Unregistered Sales of Equity Securities.

The information provided in Item 1.01 with respect
to the issuance of the shares of Series E Preferred Stock pursuant to the Securities Purchase Agreement is incorporated herein by reference.
All such securities will not be registered under the Securities Act in reliance on the exemption from registration provided by Section
4(a)(2) of the Securities Act and/or Rule 506 of Regulation D promulgated thereunder, or under any state securities laws. The Company
relied on this exemption from registration in entering into the Securities Purchase Agreement and the Company will rely upon this exemption
from registration in issuing such securities based in