Company: PFSA
Filing Date: 2025-10-21
Form Type: 8-K
Source: 0001213900-25-100443
Chunk: 0

Company: Profusa, Inc.
Filing Date: 2025-10-21
Form: 8-K
Item: Item 7.01
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Item 7.01 Regulation FD Disclosure

On October 20, 2025, Profusa, Inc. (the “ Company”)
published an updated investor presentation to its website (the “ Investor Presentation”). The Company may use the Investor
Presentation, possibly with modifications, in presentations from time to time thereafter to current and potential investors, analysts,
lenders, business partners, customers, employees and others with an interest in the Company and its business.

The Investor Presentation contains forward-looking
statements. See page two of the Investor Presentation for a discussion of certain forward-looking statements that are included therein
and the risks and uncertainties related thereto.

A copy of the Investor Presentation is attached
hereto as Exhibit 99.1.

The information provided in Item 7.01 of this
Current Report on Form 8-K, including Exhibit 99.1 attached hereto, is being furnished and shall not be deemed “filed” for
purposes of Section 18 of the Exchange Act, or otherwise subject to the liabilities of that section. Such information shall not be deemed
incorporated by reference into any filing of the Company under the Securities Act or the Exchange Act, whether made before or after the
date hereof, regardless of any general incorporation language in such filing, except as otherwise expressly set forth by specific reference
in such filing.

Item 9.01 Financial Statements and Exhibits.