Company: BDRX
Filing Date: 2025-09-26
Form Type: F-3
Source: 0001214659-25-014255
Chunk: 69

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-09-26
Form: F-3
Chunk 69
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of the Depositary Shares issued will, unless specifically requested to the contrary, be part of the depositary’s direct registration
system, and a registered holder will receive periodic statements from the depositary which will show the number of Depositary Shares registered
in such ADR holder’s name. An ADR holder can request that the Depositary Shares not be held through the depositary’s direct
registration system and that a certificated ADR be issued.

How do ADR holders cancel a Depositary Share and obtain deposited securities?

When you turn in your ADR
certificate at the depositary’s office, or when you provide proper instructions and documentation in the case of direct registration
Depositary Shares, subject to the provisions of or governing our Ordinary Shares (including, without limitation, our governing documents
and all applicable laws, rules and regulations), the depositary will, upon payment of certain applicable fees, charges and taxes, deliver
the underlying Ordinary Shares to you or upon your written order. Delivery of deposited securities in certificated form will be made at
the custodian’s office (or from the custodian to the extent dematerialized). At your risk, expense and request, the depositary may
deliver deposited securities (including any certificates therefor) at such other place as you may request.

The depositary may only restrict the withdrawal
of deposited securities in connection with:

| · | temporary delays caused by closing our transfer books or those of the depositary or the deposit of Ordinary 
 Shares in connection with voting at a shareholders’ meeting, or the payment of dividends;                   |

| · | the payment of fees, taxes and similar charges; or |

| · | compliance with any U.S. or foreign laws or governmental regulations relating to the ADRs or to the withdrawal 
 of deposited securities.                                                                                       |

This right of withdrawal may not be limited by
any other provision of the Deposit Agreement.

| 41 |

Record Dates

The depositary may, after
consultation with us if practicable, fix record dates (which, to the extent applicable, shall be as near as practicable to any corresponding
record dates set by us) for the determination of the registered ADR holders who will be entitled (or obligated, as the case may be):

| · | to receive any distribution on or in respect of deposited securities, |

| · | to give instructions for the exercise of voting rights, |

| · | to pay any fees assessed by, or owing to, the depositary for administration