Company: DNLI
Filing Date: 2025-08-11
Form Type: 10-Q
Source: 0001714899-25-000170
Chunk: 204

Company: Denali Therapeutics Inc.
Filing Date: 2025-08-11
Form: 10-Q
Item: Part I, Item 1
Chunk 204
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 and as such, the measurement of this investment remains unchanged, with the $15.0 million included within other non-current assets in the Condensed Consolidated Balance Sheets as of both June 30, 2025 and December 31, 2024.

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11.    Segment Information

The Company has one operating segment with the goal to discover, develop and commercialize therapeutics (“Therapeutics”). There have been no material changes to the Company's segment structure, the basis of segmentation, or the measurement basis for segment profit or loss or segment assets, compared to those disclosed in Note 14, "Segment Information", to the consolidated financial statements in the Company's 2024 Annual Report on Form 10-K. The following table presents selected financial information with respect to the Company’s single operating segment for the three and six months ended June 30, 2025 and 2024 (in thousands):Therapeutics SegmentThree Months Ended June 30,Six Months Ended June 30,2025202420252024ExpensesExternal research and development expenses - TV programs, including cost sharing$37,594 $30,247 $84,052 $65,931 External research and development expenses - small molecule programs, including cost sharing2,787 12,596 11,641 25,717 Other research and development expenses22,060 14,504 42,706 30,386 Personnel related research and development expenses40,255 34,052 80,524 76,381 Total research and development expenses102,696 91,399 218,923 198,415 Personnel related general and administrative expenses20,115 17,105 38,853 36,190 Other general and administrative expenses12,152 8,089 22,767 14,240 Total general and administrative expenses32,267 25,194 61,620 50,430 Segment operating expenses134,963 116,593 280,543 248,845 Segment gain from divestiture of small molecule programs— — — 14,537 Segment loss from operations(134,963)(116,593)(280,543)(234,308)Segment interest and other income, net10,844 17,567 23,454 33,480 Segment loss before income taxes$(124,119)$(99,026)$(257,089)$(200,828)