Company: PFSA
Filing Date: 2025-09-23
Form Type: DEF 14A
Source: 0001213900-25-090286
Chunk: 0

Company: Profusa, Inc.
Filing Date: 2025-09-23
Form: DEF 14A
Chunk 0
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 _________________________________ SCHEDULE 14A _________________________________ Proxy Statement Pursuant to Section 14(a) of the
Securities Exchange Act of 1934
(Amendment No. )

| Filed by the Registrant                    |     | ☒ |
| Filed by a Party other than the Registrant |     | ☐ |

Check the appropriate box:

| ☐ |     | Preliminary Proxy Statement                                                     |
| ☐ |     | Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) |
| ☒ |     | Definitive Proxy Statement                                                      |
| ☐ |     | Definitive Additional Materials                                                 |
| ☐ |     | Soliciting Materials Pursuant to Rule 14a-12                                    |

PROFUSA, INC. (Name of Registrant as Specified in its Charter) ________________________________________________________________ (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant) Payment of Filing Fee (Check all boxes that apply):

| ☒ |     | No fee required                                                                                     |
| ☐ |     | Fee paid previously with preliminary materials.                                                     |
| ☐ |     | Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11 |

PROFUSA, INC. 626 Bancroft Way Suite A Berkeley, CA 94710 NOTICE OF SPECIAL MEETING OF STOCKHOLDERS
TO BE HELD ON OCTOBER 7, 2025 September22, 2025 Dear Fellow Stockholders: On behalf of the Board of Directors, I cordially invite you to attend the 2025 special meeting of stockholders (the “ Special Meeting”) of Profusa, Inc., which will be held on October7, 2025, beginning at 10:00 a.m., Eastern Time. The Special Meeting will be a completely virtual meeting of stockholders, which will be conducted via teleconference. The dial -ininformation for the meeting can be found at www.cleartrustonline.com / pfsa.In addition, you will be able to register to attend, vote and examine the list of Stockholders entitled to vote at the Special Meeting by visiting www.cleartrustonline.com / pfsaand entering the twelve -digitcontrol number found on your proxy card, included in your proxy materials