Company: RCUS
Filing Date: 2025-04-22
Form Type: DEF 14A
Source: 0001724521-25-000052
Chunk: 0

Company: Arcus Biosciences, Inc.
Filing Date: 2025-04-22
Form: DEF 14A
Chunk 0
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#### SCHEDULE 14A INFORMATION
<div align='center'>Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

(Amendment No.__)</div>

| Filed by the Registrant                    |     | ý |
| Filed by a Party other than the Registrant |     | o |

Check the appropriate box:

| o |     | Preliminary Proxy Statement                                                     |
| o |     | Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) |
| ý |     | Definitive Proxy Statement                                                      |
| o |     | Definitive Additional Materials                                                 |
| o |     | Soliciting Material Pursuant to § 240.14a-12                                    |

#### Arcus Biosciences, Inc.
<div align='center'>(Name of Registrant as Specified in Its Charter)</div>

<div align='center'>(Name of Person(s) Filing Proxy Statement if Other Than the Registrant)</div>

Payment of Filing Fee (Check all boxes that apply)

| ý |     | No fee required.                                                                                     |
| o |     | Fee paid previously with preliminary materials.                                                      |
| o |     | Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11. |

#### ARCUS BIOSCIENCES, INC.
<div align='center'>3928 Point Eden Way

Hayward, CA 94545

(510) 694-6200</div>

### NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

#### To Be Held on June 10, 2025
Dear Stockholder:

You are cordially invited to attend the 2025 Annual Meeting of Stockholders (the "Annual Meeting"), of Arcus Biosciences, Inc., a Delaware corporation (“Arcus”). The Annual Meeting will be held on Tuesday, June 10, 2025, at 8:30 a.m. Pacific Time. The Annual Meeting will be a completely virtual meeting of stockholders, which will be conducted via live webcast. You will be able to attend the Annual Meeting and submit your questions and vote your shares online during the meeting by visiting www.virtualshareholdermeeting.com/RCUS2025 and using your 16-digit control number to enter the Annual Meeting. The stockholder list and instructions on how stockholders of record can view the stockholder list