Company: SHPH
Filing Date: 2025-02-27
Form Type: 424B3
Source: 0001493152-25-008474
Chunk: 156

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-02-27
Form: 424B3
Chunk 156
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     |     | $                              | 524,303 |     | $ | 429,555 |
| Other Audit Fees |     | $                              |       - |     | $ |       - |
| Tax Fees 2       |     | $                              |       - |     | $ |       - |
| Total fees       |     | $                              | 524,303 |     | $ | 429,555 |

| 1. | Audit                                                                                                                               
 fees consist of fees for professional services rendered by the principal accountant for the audit of the Company’s annual financial 
 statements and review of the financial statements included in the Company’s Form 10-K and Form 10-Q and for services that are       
 normally provided by the accountant in connection with statutory and regulatory filings or engagements. Fees include out of scope   
 costs related to convertible notes and warrants.                                                                                    |
| 2. | Tax                                                                                                                                 
 fees consist of professional services rendered by our principal accountant for tax compliance, tax advice and tax planning.         |

Audit Committee Pre-Approval Policies

The Audit Committee is tasked with pre-approving any non-audit services proposed to be provided to the Company by the independent auditors.

| 84 |

<div align='center'>PART IV</div>

Item 15. Exhibit and Financial Statement Schedules

| Exhibit 
 No.     |     | Description                                                                                                                                                                                                                                                                                                                                                                     |
| 3.1     |     | Amended and Restated Certificate of Incorporation (incorporated by reference to Exhibit 3.1 to the Registration Statement on Form S-1 (File No. 333-265429) filed on June 3, 2022).                                                                                                                                                                                             |
| 3.2     |     | Certificate of Amendment to Amended and Restated Certificate of Incorporation, effective March 30, 2022 (incorporated by reference to Exhibit 3.2 to the Registration Statement on Form S-1 (File No. 333-265429) filed on June 3, 2022).                                                                                                                                       |
| 3.3     |     | Amended and Restated Certificate of Designation for Series A Convertible Preferred Stock, effective April 6, 2022 (incorporated by reference to Exhibit 3.4 to the Registration Statement on Form S-1 (File No. 333-265429) filed on June 3, 2022).                                                                                                                             |
| 3.4     |     | Certificate of Amendment to Amended and