Company: MTB-PJ
Filing Date: 2025-06-11
Form Type: 424B2
Source: 0001193125-25-139262
Chunk: 0

Company: M&T BANK CORP
Filing Date: 2025-06-11
Form: 424B2
Chunk 0
---
 The Depository Trust Company and its direct participants on or about June 17, 2025. Joint Book-Running Managers

| Citigroup |     | Morgan Stanley |     | RBC Capital Markets |

Co-Managers

| Drexel Hamilton |     | Jefferies |     | M&T Securities |

June 10, 2025

USE OF PROCEEDS

We will use the net proceeds from the sale of the Notes for general corporate purposes, including investments in and advances to our bank and
nonbank subsidiaries, reduction of outstanding borrowings or indebtedness, short and long-term investments and financing possible future acquisitions including, without limitation, the acquisition of banking and nonbanking companies and financial
assets and liabilities. All or a portion of the net proceeds from the sale of Notes may also be used to finance, in whole or in part, our repurchase of common shares pursuant to any share repurchase program securities repurchases undertaken from
time to time. The precise amounts and timing of the application of proceeds will vary with liquidity and funding requirements.

PS-1

CERTAIN UNITED STATES FEDERAL INCOME TAX CONSIDERATIONS

The Company believes that the Notes should be treated as variable rate Notes that are not issued with original issue discount for United
States federal income tax purposes. See the discussion in the prospectus supplement under “Certain United States Federal Income Tax Considerations” for a discussion of the United States federal income tax consequences of investing in the
Notes.

PS-2

SUPPLEMENTAL INFORMATION CONCERNING THE PLAN OF DISTRIBUTION We have entered into a terms agreement, dated June 10, 2025 (the “Terms Agreement”), with the agents named below. Subject to the terms and conditions set forth in the Terms Agreement, we have agreed to sell to the agents, and the agents have agreed, severally and not jointly, to purchase, the principal amount of Notes set forth opposite their respective names below:

| Agent                         |     | Amount   
 of Notes |             |
|:------------------------------|:----|:---------|------------:|
| Morgan Stanley & Co. LLC      |     | $        | 262,500,000 |
| Citigroup Global Markets Inc. |     |          | 225,000,000 |
| RBC Capital Markets, LLC      |     |          | 225,000,000 |
| Drexel Hamilton, LLC          |     |          |  15,000,000 |
| Jefferies LLC                 |