Company: CERO
Filing Date: 2025-08-11
Form Type: S-3
Source: 0001213900-25-073849
Chunk: 29

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-08-11
Form: S-3
Chunk 29
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 that is
not deemed filed under such provisions, (i) on or after the date of filing of the registration statement containing this prospectus and
prior to the effectiveness of the registration statement and (ii) on or after the date of this prospectus until the earlier of the date
on which all of the securities registered hereunder have been sold or the registration statement of which this prospectus is a part has
been withdrawn, shall be deemed incorporated by reference in this prospectus and to be a part of this prospectus from the date of filing
of those documents and will be automatically updated and, to the extent described above, supersede information contained or incorporated
by reference in this prospectus and previously filed documents that are incorporated by reference in this prospectus.

Nothing in this prospectus
shall be deemed to incorporate information furnished but not filed with the SEC pursuant to Item 2.02, 7.01 or 9.01 of Form 8-K. Upon
written or oral request, we will provide without charge to each person, including any beneficial owner, to whom a copy of the prospectus
is delivered a copy of any or all of the reports or documents incorporated by reference herein (other than exhibits to such documents,
unless such exhibits are specifically incorporated by reference herein). You may request a copy of these filings, at no cost, by writing
or telephoning us at the following address or phone number:

<div align='center'>CERo Therapeutics Holdings, Inc.

201 Haskins Way, Suite 230

South San Francisco, CA 94080

Attention: Chief Executive
Officer

Telephone Number: (650) 407-2376

14

Up to 9,615,385 Shares of Common Stock

CERO THERAPEUTICS HOLDINGS, INC.

PROSPECTUS

, 2025</div>

You should rely only on the information contained in this prospectus or any supplement or amendment hereto. We have not authorized anyone to provide you with different information. You should not assume that the information contained in this prospectus or any supplement or amendment hereto is accurate as of any date other than the date of this prospectus or any such supplement or amendment. Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

<div align='center'>PART II

INFORMATION NOT REQUIRED IN PROSPECTUS