Company: GLPG
Filing Date: 2025-03-27
Form Type: 20-F
Source: 0001558370-25-003806
Chunk: 170

Company: GALAPAGOS NV
Filing Date: 2025-03-27
Form: 20-F
Item: Item 4
Chunk 170
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 protein kinases which also attach phosphates to other amino acids such as serine and threonine. GLPG3667 is a reversible and selective TYK2 kinase domain inhibitor
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125

 Ulcerative colitis (UC)     UC is an IBD causing chronic inflammation of the lining of the colon and rectum (unlike CD with inflammation throughout the gastrointestinal tract)
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Variable heavy (VH) domain   The variable domain of an immunoglobulin heavy chain is a part of an antibody that binds to a specific antigen                                     
Vein-to-vein time            The time between leukapheresis and infusion in the patient                                                                                         
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C.     Organizational structure.
As of December 31, 2024, we had 10 subsidiaries. The following table sets out for each of our subsidiaries, the country of incorporation, and percentage ownership and voting interest held by us (directly or indirectly through our subsidiaries) (situation as per December 31, 2024).
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On January 7, 2025, we incorporated Galapagos (Shanghai) Bioscience Co., Ltd., in the People’s Republic of China, and on February 14, 2025 we incorporated XYZ SpinCo NV.
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Company                                      Country of incorporation       Percentage ownership and    
                                                                                     voting interest    
Galapagos B.V.                           ​   The Netherlands            ​                       100%   ​
Galapagos GmbH                           ​   Switzerland                ​                       100%   ​
GLPG US Holding Inc.                     ​   United States              ​                       100%   ​
Galapagos SASU                           ​   France                     ​                       100%   ​
Galapagos Real Estate Belgium BV         ​   Belgium                    ​                       100%   ​
Galapagos Real Estate Netherlands B.V.   ​   The Netherlands            ​                       100%   ​
Galapagos U.K. Limited                   ​   United Kingdom             ​                       100%   ​
GLPG US Inc.                             ​   United States              ​                       100%   ​
Xenometrix, Inc. in liquidation          ​   United States              ​                       100%   ​
Galapagos Holding PTE. LTD.              ​   Singapore                  ​                       100%   ​
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D.     Property, plants and equipment.
We have our