Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 388

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 388
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 method permitted pursuant to applicable law. |

The Selling Securityholders
may also sell securities under Rule 144 or any other exemption from registration under the Securities Act, if available, rather than
under this prospectus.

Broker-dealers engaged by
the Selling Securityholders may arrange for other brokers-dealers to participate in sales. Broker-dealers may receive commissions or discounts
from the Selling Securityholders (or, if any broker-dealer acts as agent for the purchaser of securities, from the purchaser) in amounts
to be negotiated, but, except as set forth in a supplement to this Prospectus, in the case of an agency transaction not in excess of a
customary brokerage commission in compliance with FINRA Rule 2121; and in the case of a principal transaction a markup or markdown in
compliance with FINRA Rule 2121.

In connection with the sale
of the securities or interests therein, the Selling Securityholders may enter into hedging transactions with broker-dealers or other financial
institutions, which may in turn engage in short sales of the securities in the course of hedging the positions they assume. The Selling
Securityholders may also sell securities short and deliver these securities to close out their short positions, or loan or pledge the
securities to broker-dealers that in turn may sell these securities. The Selling Securityholders may also enter into option or other transactions
with broker-dealers or other financial institutions or create one or more derivative securities which require the delivery to such broker-dealer
or other financial institution of securities offered by this prospectus, which securities such broker-dealer or other financial institution
may resell pursuant to this prospectus (as supplemented or amended to reflect such transaction).

The Selling Securityholders
and any broker-dealers or agents that are involved in selling the shares may be deemed to be “underwriters” within the
meaning of the Securities Act in connection with such sales. In such event, they will be subject to the prospectus delivery
requirements of the Securities Act, any commissions received by such broker-dealers or agents and any profit on the resale of
the shares purchased by them may be deemed to be underwriting commissions or discounts under the Securities Act. The Selling Securityholders
has informed us that it does not have any agreement or understanding, directly or indirectly, with any person to distribute the Class A
Ordinary Shares.

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We may be required to amend
or supplement this prospectus in the event that (a) a