Company: APM
Filing Date: 2025-10-14
Form Type: 424B5
Source: 0001213900-25-098635
Chunk: 75

Company: Aptorum Group Ltd
Filing Date: 2025-10-14
Form: 424B5
Chunk 75
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 either individually or as units
comprised of one or more of the other securities. The prospectus supplement for each offering of securities will describe in detail the
plan of distribution for that offering. For general information about the distribution of securities offered, please see “Plan of
Distribution” in this prospectus.

This prospectus provides a
general description of the securities we may offer. We will provide the specific terms of the securities offered in one or more supplements
to this prospectus. We may also authorize one or more free writing prospectuses to be provided to you in connection with these offerings.
The prospectus supplement and any related free writing prospectus may add, update or change information contained in this prospectus.
You should read carefully this prospectus, the applicable prospectus supplement and any related free writing prospectus, as well as the
documents incorporated or deemed to be incorporated by reference, before you invest in any of our securities. This prospectus may not be used to offer or sell any securities unless accompanied by the applicable prospectus supplement.

Pursuant to General Instruction
I.B.5. of Form F-3, in no event will we sell the securities covered hereby in a public primary offering with a value exceeding more than
one-third of the aggregate market value of our Ordinary Shares in any 12-month period so long as the aggregate market value of our outstanding
Ordinary Shares held by non-affiliates remains below $75,000,000. During the 12 calendar months prior to and including the date of this
prospectus, we have not offered or sold any securities pursuant to General Instruction I.B.5 of Form F-3.

In this F-3, we are also registering
for resale our Class A Ordinary Shares underlying 540,540 selling shareholder warrants identified below (the “Resale Shares”).
On January 6, 2020, we filed with the SEC a registration statement on Form F-3 (File No. 333-235819) utilizing a shelf registration process
(the “Shelf F3”) relating to the securities described in the prospectus supplement dated February 25, 2020 (the “Warrant
Supplement”) and the prospectus supplement dated March 26, 2021 (the “At the Market Supplement,” together with the Warrant
Supplement, the “Prospectus Supplements”), which registration statement was declared effective on January 15, 2020 (the “2020
F-3”). Under this shelf registration