Company: RCUS
Filing Date: 2025-02-18
Form Type: 424B5
Source: 0001193125-25-028669
Chunk: 24

Company: Arcus Biosciences, Inc.
Filing Date: 2025-02-18
Form: 424B5
Chunk 24
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8 in connection with the registration of common stock issuable under any employee benefit plan adopted and approved by the company’s board of directors; (v) any common stock sold to Gilead pursuant to that certain Third Amended and Restated Common Stock Purchase Agreement, dated January 29, 2024, by and between the company and Gilead, to the extent required by the terms of such agreement; (vi) the issuance of up to 7.5% of the outstanding shares of the company’s common stock or securities convertible into or exercisable or exchangeable for shares of the company’s common stock pursuant to a strategic partnership, joint venture, S-18

merger, collaboration, lending or other contractual arrangement, or in connection with the acquisition or license by the company of any business, products or technologies, provided that such
recipients enter into a lock-up agreement with the underwriters; and

(vii) the issuance and sale of common stock pursuant to that certain
Equity Distribution Agreement, dated February 28, 2023, by and among the company, Goldman Sachs & Co. LLC and Leerink Partners LLC, provided that no sales shall be made under such agreement until 30 calendar days after the date of this
prospectus.

In addition, the company’s executive officers, directors, and a certain stockholder have also agreed with the underwriters, subject to
certain exceptions, not to directly or indirectly offer for sale, sell, pledge, enter into any swap or other derivatives transaction that transfers any of the economic benefits or risks of ownership of the company’s common stock, or otherwise
dispose of any shares of the company’s common stock or any securities that may be converted into or exchanged for any shares of the company’s common stock during the period from the date of this prospectus supplement continuing through the
date 60 days after the date of this prospectus supplement, except with the prior written consent of the representatives. These restrictions do not apply, subject in certain cases to various conditions, to certain transactions, including:

(i) transfers of a bona fide gift or gifts, charitable contributions or for bona fide estate planning purposes;

(ii) transfers upon death by will or intestate succession;

(iii) to any member of the individual’s immediate family or to any trust for the direct or indirect benefit of the stockholder or the
immediate family of the stockholder;

(iv) to a partnership, limited liability company or other entity of which the lock-up party and their immediate family