Company: SMNR
Filing Date: 2025-08-13
Form Type: 424B3
Source: 0001193125-25-179226
Chunk: 834

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-08-13
Form: 424B3
Chunk 834
---

| Exhibit A |     | Form of Certificate of Incorporation            |
| Exhibit B |     | Form of Bylaws                                  |
| Exhibit C |     | Form of Registration Rights Agreement           |
| Exhibit D |     | Plan of Domestication                           |
| Exhibit E |     | Domesticated Parent Certificate of Designations |

A-1-iii

AGREEMENT AND PLAN OF MERGER

This AGREEMENT AND PLAN OF MERGER (the “”), dated as of August 30, 2024 (the “”), is made and entered into by and among Denali Capital Acquisition Corp., a Cayman Islands exempted company (which shall migrate to and domesticate as a Delaware corporation prior to the Closing, “”), Denali
Merger Sub Inc., a Delaware corporation and wholly owned subsidiary of Parent (“”), and Semnur Pharmaceuticals, Inc., a Delaware corporation (the “”).

W I T N E S E T H :

WHEREAS, the Company is a subsidiary of Scilex Holding Company, a Delaware corporation (“”), which is a publicly
owned company listed on Nasdaq;

WHEREAS, the Company is in the business of identifying potential
non-opioid pain therapy candidates, undertaking preclinical studies and clinical trials of its product candidate SP-102 and establishing research and development and
manufacturing collaborations (the “”);

WHEREAS, Parent is a blank check company formed for the sole purpose of
entering into a share exchange, asset acquisition, share purchase, recapitalization, reorganization or other similar business combination with one or more businesses or entities;

WHEREAS, prior to the Effective Time and subject to the conditions of this Agreement, Parent shall migrate to and domesticate as a Delaware
corporation in accordance with Section 388 of the General Corporation Law of the State of Delaware, as amended (the “”) and de-register in the Cayman Islands in accordance with
Section 206 of the Cayman Companies Act (the “”);

WHEREAS, concurrently with the Domestication,
Parent shall file a certificate of incorporation with the Secretary of State of the State of Delaware and adopt bylaws in the forms attached as and , respectively, with such
changes as may be agreed in writing by Parent and the Company (such certificate of incorporation, the “” and such bylaws, the “”);

WHEREAS, simultaneously with the execution and delivery of this Agreement, the Company and Scilex have executed and delivered that certain
Contribution and Satisfaction of Indebtedness Agreement (the