Company: HRTX
Filing Date: 2025-08-08
Form Type: 10-Q
Source: 0000950170-25-105475
Chunk: 8

Company: HERON THERAPEUTICS, INC. /DE/
Filing Date: 2025-08-08
Form: 10-Q
Item: Item 6
Chunk 8
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The exhibits listed on the Exhibit Index hereto are filed or furnished (as stated therein) as part of this Quarterly Report on Form 10‑Q.

     ExhibitNumber
      
     Description

     10.1+*
      
     Amendment No. 3 to Co-Promotion Agreement, dated as of January 5, 2024, by and between the Company and CrossLink Network, LLC

     10.2+*
      
     Amendment No. 4 to Co-Promotion Agreement, dated as of January 5, 2024, by and between the Company and CrossLink Network, LLC

     10.3+†
      
     Management Retention Agreement, dated April 28, 2025, by and between the Company and Mark Hensley

     10.4+*
      
     Amendment No. 5 to Co-Promotion Agreement, dated as of January 5, 2024, by and between the Company and CrossLink Network, LLC

     31.1+
      
     Certification of Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

     31.2+
      
     Certification of Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

     32.1++
      
     Certifications of Principal Executive Officer and Principal Financial Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

     101.INS
      
     XBRL Instance Document – the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.

     101.SCH
      
     Inline XBRL Taxonomy Extension Schema Document

     101.CAL
      
     Inline XBRL Taxonomy Extension Calculation Linkbase Document

     101.DEF
      
     Inline XBRL Extension Definition 

     101.LAB
      
     Inline XBRL Taxonomy Extension Label Linkbase Document 

     101.PRE
      
     Inline XBRL Taxonomy Extension Presentation Linkbase Document

     104
      
     Cover Page Interactive Data File (embedded within the Inline