Company: APM
Filing Date: 2025-10-14
Form Type: 424B5
Source: 0001213900-25-098635
Chunk: 103

Company: Aptorum Group Ltd
Filing Date: 2025-10-14
Form: 424B5
Chunk 103
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 would have received if they had converted
the debt securities before the consolidation, merger or sale.

<div align='center'>19</div>

Events of Default Under the Indenture

The following are events of
default under the indentures in the forms initially filed as exhibits to the registration statement with respect to any series of debt
securities that we may issue:

| ● | if we fail to pay interest when due and payable and our failure                   
 continues for 90 days and the time for payment has not been extended or deferred; |

| ● | if we fail to pay the principal, sinking fund payment or premium,                       
 if any, when due and payable and the time for payment has not been extended or delayed; |

| ● | if we fail to observe or perform any other covenant contained                                                                               
 in the debt securities or the indentures, other than a covenant specifically relating to another series of debt securities, and our failure 
 continues for 90 days after we receive notice from the debenture trustee or holders of at least 25% in aggregate principal amount of        
 the outstanding debt securities of the applicable series; and                                                                               |

| ● | if specified events of bankruptcy, insolvency or reorganization 
 occur.                                                          |

If an event of default with
respect to debt securities of any series occurs and is continuing, other than an event of default specified in the last bullet point above,
the debenture trustee or the holders of at least 25% in aggregate principal amount of the outstanding debt securities of that series,
by notice to us in writing, and to the debenture trustee if notice is given by such holders, may declare the unpaid principal of, premium,
if any, and accrued interest, if any, due and payable immediately. If an event of default specified in the last bullet point above occurs
with respect to us, the principal amount of and accrued interest, if any, of each issue of debt securities then outstanding shall be due
and payable without any notice or other action on the part of the debenture trustee or any holder.

The holders of a majority
in principal amount of the outstanding debt securities of an affected series may waive any default or event of default with respect to
the series and its consequences, except defaults or events of default regarding payment of principal, premium, if any, or interest, unless
we have cured the default or event of default in accordance with the indenture. Any waiver shall cure the default or event of default.

Subject to the terms of the
indentures,