Company: CMND
Filing Date: 2025-11-19
Form Type: 424B5
Source: 0001213900-25-112329
Chunk: 1

Company: Clearmind Medicine Inc.
Filing Date: 2025-11-19
Form: 424B5
Chunk 1
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| Where You Can Find More Information               |     |   28 |
| Incorporation of Certain Documents by Reference   |     |   29 |
| Enforceability of Civil Liabilities               |     |   30 |
| Expenses                                          |     |   30 |

<div align='center'>S-i

ABOUT THIS PROSPECTUS SUPPLEMENT</div>

A registration statement on
Form F-3 (File No. 333-275991) utilizing a shelf registration process relating to the securities described in this prospectus supplement
was declared effective on December 26, 2023. Under that shelf registration statement, of which this prospectus supplement is a part, we
may, from time to time, sell up to an aggregate of $50 million of Common Shares, warrants and units. As of November 18, 2025, we have
sold approximately $4.56 million of our securities under that shelf registration statement. We sometimes refer to the Common Shares
as the “securities” throughout this prospectus.

This document contains two
parts. The first part is this prospectus supplement, which describes the terms of this offering of the Common Shares, and also adds, updates
and changes information contained in the accompanying prospectus and the documents incorporated herein and therein by reference. The second
part is the accompanying prospectus, which gives more general information about us, some of which may not apply to this offering. You
should read both this prospectus supplement and the accompanying prospectus, including the information incorporated by reference herein
and therein. To the extent the information contained in this prospectus supplement differs or varies from the information contained in
the accompanying prospectus or any document filed prior to the date of this prospectus supplement and incorporated herein or therein by
reference, the information in this prospectus supplement will control; provided, that if any statement in one of these documents is inconsistent
with a statement in another document having a later date, the statement in the document having the later date modifies or supersedes the
earlier statement. In addition, this prospectus supplement and the accompanying prospectus do not contain all of the information provided
in the registration statement that we filed with the SEC that contains the accompanying prospectus (including the exhibits to the registration
statement). For further information about us, you should refer to that registration statement, which you can obtain from the SEC as described
elsewhere in this prospectus supplement under “Where You Can Find Additional