Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119831
Chunk: 444

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 444
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 subject to certain adjustments, including (but not limited to) for stock dividends, stock splits, combinations and reclassifications
of Common Stock.

A holder (together with its affiliates) may not exercise any portion of the February 2024 BDO Firm Warrants to the
extent that the holder would own more than 4.99% of the Common Stock outstanding immediately after exercise (the “February 2024 BDO Beneficial Ownership Limitation”). However, upon at least 61 days’ prior notice from the holder to the
Company, a holder may increase or decrease the February 2024 BDO Beneficial Ownership Limitation in accordance with the terms of the February 2024 BDO Firm Warrants, provided that it does not exceed 9.99%.

The February 2024 BDO Representative Warrants are exercisable immediately from the date of issuance and have the same terms as the February
2024 BDO Firm Warrants described above, except that the exercise price of the February 2024 BDO Representative Warrants is $74.38 per share.

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The foregoing summaries of the terms and conditions of the February 2024 BDO Warrants do not
purport to be complete and are qualified in their entirety by reference to the copies of the forms of February 2024 BDO Warrants that are filed as an exhibit to the registration statement of which this prospectus forms a part.

April 2024 RDO Warrants

On
April 23, 2024, we entered into the April 2024 RDO Purchase Agreement, pursuant to which we sold, in a registered direct offering, (i) the April 2024 RDO Common Warrants to purchase up to 428,572 shares of Common Stock, issued to the
investor, with an exercise price of $38.50 per share and (ii) the April 2024 RDO Placement Agent Warrants to purchase up to 34,286 shares of Common Stock, issued to the Placement Agents, as the exclusive placement agents in connection with the
offering, with an exercise price of $43.75 per share. As of March 31, 2025, all of the April 2024 RDO Warrants remain outstanding.

Subject to certain ownership limitations, the April 2024 RDO Common Warrants are exercisable on the
six-month anniversary from the date of issuance and expire on the five-year anniversary of the date of issuance. The exercise price of the April 202