Company: TVRD
Filing Date: 2025-11-13
Form Type: 424B3
Source: 0001104659-25-111336
Chunk: 156

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-11-13
Form: 424B3
Chunk 156
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 be approved by the FDA, regardless of whether Tvardi has registered it, or applied to register it, as a trademark. The FDA
typically conducts a review of proposed product names, including an evaluation of potential for confusion with other product names. If
the FDA objects to any of Tvardi’s proposed product names, Tvardi may be required to expend significant additional resources in
an effort to identify a usable substitute name that would qualify under applicable trademark laws, not infringe the existing rights of
third parties and be acceptable to the FDA. If Tvardi is unable to establish name recognition based on its trademarks and trade names,
Tvardi may not be able to compete effectively, and its business may be adversely affected.

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Intellectual property rights do not necessarily address all potential threats to its business.

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The degree of future protection afforded by Tvardi’s
intellectual property rights is uncertain because intellectual property rights have limitations, and may not adequately protect its business,
or permit Tvardi to maintain its competitive advantage. The following examples are illustrative:

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| ● | others may be able to make products that are competitive to Tvardi’s product candidates or any of its product candidates but that are not covered by the claims of its patent portfolio; |

| ● | others may independently develop similar or alternative technologies or otherwise circumvent any of Tvardi’s technologies without infringing its patent portfolio; |

| ● | Tvardi or any of its collaborators might not have been the first to invent the inventions covered by its patent portfolio; |

| ● | Tvardi or any of its collaborators might not have been the first to file patent applications covering certain of the patents or patent applications that it or they own or have obtained a license, or will own or will have obtained a license; |

| ● | it is possible that Tvardi’s own and in-licensed pending patent applications or those that Tvardi may file in the future will not lead to issued patents; |

| ● | others may have access to the same intellectual property rights licensed to Tvardi on a non-exclusive basis in the future; |

| ● | issued patents that Tvardi owns or in-licensed may not provide Tvardi with any competitive advantage, or may be held invalid or unenforceable, including as a result of legal challenges by its competitors; |

| ● | Tvardi’s competitors might conduct research and development activities in countries where it does not have patent rights, or in countries where research and development