Company: CNTB
Filing Date: 2025-09-10
Form Type: POS AM
Source: 0001193125-25-200186
Chunk: 72

Company: Connect Biopharma Holdings Ltd
Filing Date: 2025-09-10
Form: POS AM
Chunk 72
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 our capital or future revenues effectively and could affect the value of any investment in our Ordinary Shares. |

| • |     | PRC regulation of loans to, and direct investments in, PRC entities by offshore holding companies may restrict 
 or prevent us from making loans or additional capital contributions to our PRC subsidiaries.                   |

8

| • |     | Any failure to comply with PRC regulations regarding the registration requirements for employee share                          
 incentive plans may subject our equity incentive plan participants or us to fines and other legal or administrative sanctions. |

| • |     | PRC regulations relating to offshore investment activities by PRC residents may limit our PRC                                                                                                
 subsidiaries’ ability to change their registered capital or distribute profits to us or otherwise expose us or our PRC resident beneficial owners to liability and penalties under PRC laws. |

| • |     | We may be treated as a resident enterprise for PRC tax purposes under the PRC Enterprise Income Tax Law, and 
 we may therefore be subject to PRC income tax on our global income.                                          |

| • |     | Dividends paid to our non-PRC investors (should we ever pay dividends)                               
 and gains on the sale of our Ordinary Shares by our non-PRC investors may become subject to PRC tax. |

| • |     | We and our shareholders face uncertainties with respect to indirect transfers of equity interests in PRC                                                            
 resident enterprises or other assets attributed to a PRC establishment of a non-PRC company, or immovable properties located in the PRC owned by non-PRC companies. |

| • |     | We and our shareholders face uncertainties with respect to reorganizations or restructurings that we may 
 undertake.                                                                                               |

| • |     | We could be adversely affected by rising political tensions and any potential conflicts between the U.S. and 
 the PRC.                                                                                                     |

| • |     | Recent litigation, regulatory scrutiny and negative publicity surrounding                                                                                
 PRC-based companies listed in the U.S. may result in increased regulatory scrutiny of us and negatively impact the trading price of our Ordinary Shares. |

| • |     | The enforcement of the PRC Labor Law, Labor Contract Law, and other labor-related regulations in the PRC may                                       
 increase our labor costs and limit our flexibility to use labor. If we fail to comply with PRC labor-related laws, we may be exposed to penalties. |

| • |     | Our business benefits from tax benefits or financial incentives and discretionary policies