Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119831
Chunk: 377

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 377
---
 executive officers are included in the section titled 
 “Executive and Director Compensation — Summary Compensation Table” above.                                                                                                                                                          |

| (2) | As of December 31, 2024, each of our current non-employee                                                                                                            
 directors held options to purchase the following number of shares of our Common Stock: Dr. Chun: 2,857; Mr. Followwill: 5,685; Dr. Wu: 2,857; and Dr. Navani: 7,142. |

| (3) | Dr. Navani was appointed to our Board on July 21, 2024. |

| (4) | Mr. Lemus resigned from our Board effective November 27, 2024. As of December 31, 2024, Lemus 
 held options to purchase 71 shares of our Common Stock.                                       |

Non-EmployeeDirector Compensation Pursuant to our Non-EmployeeDirector Compensation Policy for the compensation of our non-employeedirectors, during 2024, each of our non-employeedirectors received annual retainers, subject to proration, for service on our Board and its committees as follows:

| Annual Cash Compensation                                                                    |     | Amount |        |
|:--------------------------------------------------------------------------------------------|:----|:-------|-------:|
| Board Members                                                                               |     | $      | 82,500 |
| Chairs of the Audit Committee, Compensation Committee, Nominating and Corporate Governance  
 Committee and Commercialization and Transaction Committee                                   |     | $      | 37,500 |
| Members of the Audit Committee, Compensation Committee, Nominating and Corporate Governance 
 Committee and Commercialization and Transaction Committee                                   |     | $      | 15,000 |
| Equity Compensation                                                                         |     | Number |        |
| Initial Stock Options                                                                       |     |        |  7,142 |
| Annual Stock Options                                                                        |     |        |  2,857 |

All annual cash compensation amounts for our non-employeedirectors are payable in equal quarterly installments in arrears, following the end of each quarter in which the service occurred, pro-ratedfor any partial months of service. The equity compensation paid to our non-employeedirectors will vest monthly over a period of 48 months from the date of grant with respect to the initial stock option grants and over a period of 12 months from the date of grant with respect to the annual stock option grants, in each case, subject to continued service through each vesting date. Additionally