Company: SHPH
Filing Date: 2025-03-31
Form Type: DEF 14A
Source: 0001641172-25-001889
Chunk: 24

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-03-31
Form: DEF 14A
Chunk 24
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 3  |     | common stock |     |           | 227,635 |
| Mira Jung         |     | Form 4  |     | common stock |     |           |     598 |

Proposal 4: Authorization of the Board of Directors to amend the Company’s amended and restated certificate of incorporation to effect a Reverse Stock Split of all of the Company’s issued and outstanding common stock by a ratio in the range of 1-for-3 to 1-for-10.

| What                                  
 am I voting on and how should I vote? |     | You                                                                                                                       
 are being asked to authorize the Board of Directors to amend the Company’s amended                                        
 and restated certificate of incorporation to effect a Reverse Stock Split of all of the Company’s                         
 issued and outstanding common stock by a ratio in the range of 1-for-3 to 1-for-10. The Board                             
 of Directors believes that conducting the Reverse Stock Split is in the best interest of                                  
 the Company and its stockholders.                                                                                         
 The                                                                                                                       
 Board of Directors therefore recommends you vote “FOR” the authorization of the Board of Directors to amend the Company’s 
 amended and restated certificate of incorporation to effect the Reverse Stock Split.                                      |

| 20 |

Vote Required

A majority of the shares present in person or by proxy and entitled to vote at our 2025 Annual Meeting is required to approve Proposal No. 4.

Overview

The Board of Directors has adopted and is recommending that our stockholders approve an amendment to our amended and restated certificate of incorporation (the “Certificate of Incorporation”) to effect the Reverse Stock Split of our common stock at a ratio ranging from any whole number between 1-for-3 and 1-for-10, with the exact ratio within such range to be determined by the Board of Directors, or a committee of the Board of Directors, in its discretion, and included in a public announcement, subject to the Board of Directors’ authority to determine when to file the amendment notwithstanding prior stockholder approval of such amendment. Pursuant to the law of the State of Delaware, our state of incorporation, the Board of Directors must adopt any amendment to our Certificate of Incorporation and submit the amendment to stockholders for their approval. The form of the proposed amendment to our Certificate of Incorporation which would be filed with the Secretary of State of the State of Delaware, is attached to this proxy statement as Appendix A.

By approving this proposal, stockholders will approve an amendment to our Certificate of