Company: RPTX
Filing Date: 2025-04-29
Form Type: DEF 14A
Source: 0001193125-25-103764
Chunk: 21

Company: Repare Therapeutics Inc.
Filing Date: 2025-04-29
Form: DEF 14A
Chunk 21
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 directors from September 2016 to April 2025, was not independent for the period for which he served as a director due to his executive leadership position with Repare.

Accordingly, a majority of our directors are independent, as required under applicable Nasdaq rules. In making its independence determination, our board of directors considered the applicable Nasdaq rules and found that none of these directors has or had any relationships that would interfere with the exercise of independent judgment in carrying out the responsibilities of a director, taking into account certain relationships and transactions that occurred in the ordinary course of business between Repare and entities with which some of our directors are or have been affiliated and all other facts and circumstances that our board of directors deemed relevant in determining their independence, including their beneficial ownership of our share capital.

#### Board Leadership Structure
Our board of directors has an independent chair, Mr. Civik, who has authority, among other things, to call and preside over meetings of our board of directors, including meetings of the independent directors, to set meeting agendas and to determine materials to be distributed to our board of directors. Accordingly, Mr. Civik has substantial ability to shape the work of our board of directors. We believe that the separation of the positions of chair of our board of directors and Chief Executive Officer reinforces the independence of our board of directors in its oversight of the business and affairs of our company. In addition, we believe that having an independent chair of our board of directors creates an environment that is more conducive to objective evaluation and oversight of management’s performance, increasing management accountability and improving the ability of our board of directors to monitor whether management’s actions are in the best interests of Repare and its shareholders. As a result, we believe that having an independent chair of our board of directors can enhance the effectiveness of our board of directors as a whole.

#### Role of the Board in Risk Oversight
One of the key functions of our board of directors is active and informed oversight of our risk management process. Our board of directors does not have a standing risk management committee. Rather, the full board retains responsibility for general oversight of risk, and administers its oversight function through various standing committees of our board of directors that address risks inherent in their respective areas of oversight. The board satisfies this responsibility through full reports by each committee chair regarding such committee’s

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**considerations and actions, as well as through regular reports directly from officers responsible for oversight of particular risks. For example, the full board receives an annual update from