Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 197

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 197
---
   Year Ended 
 December 31, 
         2023 |
|:----------------------------------------------|:----|:--|-------------:|:----|:--|-------------:|
| Research and Development Expenses:            |     |   |              |     |   |              |
| Contracted research organizations services    |     | $ |      166,972 |     | $ |    1,387,534 |
| Sponsored research                            |     |   |       39,972 |     |   |       17,149 |
| Amortization and depreciation                 |     |   |      251,567 |     |   |    1,071,455 |
| Consultation                                  |     |   |       44,872 |     |   |    1,207,188 |
| Loss on impairments of an intangible asset    |     |   |      128,128 |     |   |      519,497 |
| Impairment of properties, plant and equipment |     |   |    1,421,782 |     |   |            - |
| Payroll expenses                              |     |   |            - |     |   |      363,139 |
| Other R&D expenses                            |     |   |      141,868 |     |   |      632,367 |
| Total Research and Development Expenses       |     | $ |    2,195,161 |     | $ |    5,198,329 |

<div align='center'>106</div>

General and administrative fees

The following table sets forth a summary of our general and administrative
expenses for the years ended December 31, 2024, and 2023. The decrease in general and administrative fees was primarily attributable
to the streamlining of our operations to focus on preparation for the Yoov Merger, which has since been abandoned.

|                                               |     |   |   Year Ended 
 December 31, 
         2024 |     |   |   Year Ended 
 December 31, 
         2023 |
|:----------------------------------------------|:----|:--|-------------:|:----|:--|-------------:|
| General and Administrative Fees:              |     |   |              |     |   |              |
| Payroll expenses                              |     | $ |      208,348 |     | $ |      893,437 |
| Rent and rates                                |     |   |