Company: RPTX
Filing Date: 2025-12-03
Form Type: PREM14A
Source: 0001193125-25-306948
Chunk: 110

Company: Repare Therapeutics Inc.
Filing Date: 2025-12-03
Form: PREM14A
Chunk 110
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 on its behalf, the Beneficial Shareholder may request a legal proxy as set forth in the VIF, which will grant the Beneficial Shareholder or its nominee the right to attend and vote at the Special Meeting. Beneficial Shareholders who wish to revoke or amend their VIFs, or revoke their proxies, should refer to the instructions received from Computershare. Attending and Participating in the Special Meeting The Special Meeting will be hosted via live webcast only. Any shareholder can attend the virtual Special Meeting live online by registering at www.proxydocs.com/RPTX .The Special Meeting will start at 10:00 a.m. (Montreal time) on January 16, 2026. Shareholders attending the Special Meeting will be afforded the same rights and opportunities to participate as they would at an in-personmeeting. In order to attend, you must register in advance at www.proxydocs.com/RPTX prior to the deadline of 10:00 a.m. (Montreal time) on January 16, 2026. Upon completing your registration, you will receive further instructions via email, including your unique links that will allow you access to the Special Meeting and will permit you to submit questions. In order to register for the Special Meeting, you will need the control number, which is included in the Notice or on your proxy card if you are a shareholder of record of common shares, or included with your voting instruction card and voting instructions received from your broker, bank or other agent if you hold your common shares in a “street name.” We recommend that you log in a few minutes before 10:00 a.m.(Montreal time) to ensure you are logged in when the Special Meeting starts. The virtual meeting room will open 15 minutes before the start of the Special Meeting. If you would like to submit a question during the Special Meeting, you may log in at www.proxydocs.com/RPTXusing your control number, type your question into the “Ask a Question” field, and click “Submit.” To help ensure that we have a productive and efficient meeting, and in fairness to all shareholders in attendance, you will also find our rules of conduct for the Special Meeting posted when you log into the platform prior to the start of the Special Meeting. These rules of conduct will include the following guidelines:

| • |     | We welcome questions from shareholders relevant to the Special Meeting. An opportunity will be provided to                                     
 present questions and comments during the question and answer session, which will include questions submitted