Company: EPR-PE
Filing Date: 2025-11-05
Form Type: 424B5
Source: 0001193125-25-266433
Chunk: 72

Company: EPR PROPERTIES
Filing Date: 2025-11-05
Form: 424B5
Chunk 72
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 risks described in the “Risk Factors” section of this prospectus and the “Risk Factors” section of our most recent Annual Report on Form 10-Kand, to the extent applicable, our Quarterly Reports on Form 10-Q,in evaluating any forward-looking statements included or incorporated by reference in this prospectus. Given these uncertainties, you should not place undue reliance on forward-looking statements. Except as required by law, we undertake no obligation to publicly update or revise any forward-looking statements included or incorporated by reference in this prospectus, whether as a result of new information, future events or otherwise. In light of the factors referred to above, the future events discussed or incorporated by reference in this prospectus may not occur and actual results, performance or achievements could differ materially from those anticipated or implied in the forward-looking statements. 4

RISK FACTORS

An investment in our securities involves certain risks. Before buying our securities, you should read and consider the risk factors included
in our periodic reports, including the risk factors described in our most recent Annual Report on Form 10-K and, to the extent applicable, our Quarterly Reports on Form
10-Q, in the prospectus supplements or any offering material relating to any specific offering, and in other information that we file with the SEC which is incorporated by reference in this prospectus. See
“Where You Can Find More Information.”

5

THE COMPANY

We are a self-administered real estate investment trust, or “REIT.” Our investment portfolio includes primarily experiential
properties, including entertainment and recreation properties, and our legacy investment in education properties.

We have elected to be
treated as a REIT for U.S. federal income tax purposes. In order to maintain our status as a REIT, we must comply with a number of requirements under U.S. federal income tax law that are discussed in “U.S. Federal Income Tax
Considerations.” The applicable prospectus supplement or other applicable offering materials delivered with this prospectus will provide information about additional U.S. federal income tax considerations related to the particular securities
being offered.

Our executive offices are located at 909 Walnut Street, Suite 200, Kansas City, Missouri 64106. Our telephone number is (816) 472-1700.

6

USE OF PROCEEDS

Unless otherwise indicated in the applicable prospectus supplement or other applicable offering materials, we intend to use the net proceeds
from any sale of securities under this prospectus for general business purposes, which may include funding the acquisition,