Company: APM
Filing Date: 2025-07-15
Form Type: DRS
Source: 0001213900-25-063899
Chunk: 372

Company: Aptorum Group Ltd
Filing Date: 2025-07-15
Form: DRS
Chunk 372
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 (including backup withholding), and such brokers or
intermediaries may be required by law to withhold such taxes.

<div align='center'>201</div>

Information with Respect to Foreign Financial Assets

Certain U.S. Holders may be
required to report information relating to the Class A Ordinary Shares, subject to certain exceptions (including an exception for Class
A Ordinary Shares held in accounts maintained by certain U.S. financial institutions). U.S. Holders should consult their tax advisors
regarding their reporting obligations with respect to their purchase, ownership and disposition of the Class A Ordinary Shares.

Material U.S. Federal Income Tax Consequences of the Domestication and the Merger

General

The following are the material
U.S. federal income tax consequences of (i) the Domestication and (ii) the DiamiR Merger to the U.S. This discussion is based upon laws
and relevant interpretations thereof in effect as of the date of this prospectus, all of which are subject to change.

The discussion below of the
U.S. federal income tax consequences to “U.S. Holders” will apply to a beneficial owner of Company shares that is for U.S.
federal income tax purposes:

| ● | an individual citizen or resident of the United States; |

| ● | a corporation (or other entity treated as a corporation) that                                                                             
 is created or organized (or treated as created or organized) in or under the laws of the United States, any state thereof or the District 
 of Columbia;                                                                                                                              |

| ● | an estate whose income is includible in gross income for U.S. 
 federal income tax purposes regardless of its source; or      |

| ● | a trust if (i) a U.S. court can exercise primary supervision                                                                   
 over the trust’s administration and one or more U.S. persons are authorized to control all substantial decisions of the trust, 
 or (ii) it has a valid election in effect under applicable U.S. Treasury regulations to be treated as a U.S. person.           |

If a beneficial owner of Company
shares is not described as a U.S. Holder and is not an entity treated as a partnership or other pass-through entity for U.S. federal income
tax purposes, such owner will be considered a “Non-U.S. Holder.” The material U.S. federal income tax consequences applicable
specifically to Non-U.S. Holders are described below under the heading “Non-U.S. Holders.”

This brief summary is
based upon