Company: VRCA
Filing Date: 2025-12-15
Form Type: S-3
Source: 0001193125-25-319225
Chunk: 3

Company: Verrica Pharmaceuticals Inc.
Filing Date: 2025-12-15
Form: S-3
Chunk 3
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 selling
stockholders may sell or dispose of their Resale Shares and Warrant Shares.

Our common stock is listed on The Nasdaq Capital Market under
the trading symbol “VRCA.” On December 12, 2025, the closing price of our common stock was $7.92 per share.

Investing in our common stock involves a high degree of risk. Before making an investment decision, please read the information under “ Risk Factors” on page 4 of this prospectus and under similar headings in any amendment or supplement to this prospectus or in any filing with the Securities and Exchange Commission that is incorporated by reference herein.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

The date of this prospectus is December , 2025.

TABLE OF CONTENTS

|                                                   |     | Page |    |
| ABOUT THIS PROSPECTUS                             |     |      | ii |
| PROSPECTUS SUMMARY                                |     |      |  1 |
| RISK FACTORS                                      |     |      |  4 |
| SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS |     |      |  5 |
| USE OF PROCEEDS                                   |     |      |  6 |
| SELLING STOCKHOLDERS                              |     |      |  7 |
| PLAN OF DISTRIBUTION                              |     |      | 12 |
| LEGAL MATTERS                                     |     |      | 15 |
| EXPERTS                                           |     |      | 15 |
| WHERE YOU CAN FIND ADDITIONAL INFORMATION         |     |      | 15 |
| INCORPORATION OF CERTAIN INFORMATION BY REFERENCE |     |      | 15 |

i

ABOUT THIS PROSPECTUS

This prospectus is part of a registration statement on Form S-3 that we filed with the
Securities and Exchange Commission (“SEC”), using a “shelf” registration process. Under this registration statement, the selling stockholders may sell from time to time in one or more offerings the common stock described in
this prospectus.

We have not authorized anyone to provide you with information other than the information that we have provided or
incorporated by reference in this prospectus and your reliance on any unauthorized information or representation is at your own risk. This prospectus may be used only in jurisdictions where offers and sales of these securities are permitted. You