Company: WSBC
Filing Date: 2025-09-11
Form Type: 424B5
Source: 0001193125-25-201360
Chunk: 103

Company: WESBANCO INC
Filing Date: 2025-09-11
Form: 424B5
Chunk 103
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forth in each applicable prospectus supplement.

19

DESCRIPTION OF OTHER SECURITIES

We will set forth in the applicable prospectus supplement a description of any warrants, purchase contracts, units or depositary shares that
may be offered pursuant to this prospectus.

20

PLAN OF DISTRIBUTION We may sell securities:

| • |     | to or through underwriters; |

| • |     | through dealers; |

| • |     | through agents; |

| • |     | directly to purchasers; or |

| • |     | through a combination of any of these methods of sale. |

In addition, we may issue the securities as a dividend or distribution or in a subscription rights offering to our existing security holders. We may directly solicit offers to purchase securities, or agents may be designated to solicit such offers. We will, in the prospectus supplement relating to such offering, name any agent that could be viewed as an underwriter under the Securities Act, and describe any commissions that we must pay. Any such agent will be acting on a best efforts basis for the period of its appointment or, if indicated in the applicable prospectus supplement, on a firm commitment basis. This prospectus may be used in connection with any offering of our securities through any of these methods or other methods described in the applicable prospectus supplement. The distribution of the securities may be effected from time to time in one or more transactions:

| • |     | at a fixed price, or prices, which may be changed from time to time; |

| • |     | at market prices prevailing at the time of sale; |

| • |     | at prices related to such prevailing market prices; or |

| • |     | at negotiated prices. |

Each prospectus supplement will describe the method of distribution of the securities and any applicable restrictions. If any underwriters or agents are utilized in the sale of the securities in respect of which this prospectus is delivered, we will enter into an underwriting agreement or other agreement with them at the time of sale to them, and we will set forth in the prospectus supplement relating to such offering the names of the underwriters or agents and the terms of the related agreement with them. If a dealer is utilized in the sale of the securities in respect of which the prospectus is delivered, we will sell such securities to the dealer, as principal. The dealer may then resell such securities to the public at varying prices to be determined by such dealer at the time of resale. If we offer securities in a subscription rights