Company: RGNX
Filing Date: 2025-06-13
Form Type: S-8
Source: 0000950170-25-086259
Chunk: 0

Company: REGENXBIO Inc.
Filing Date: 2025-06-13
Form: S-8
Chunk 0
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As filed with the Securities and Exchange Commission on June 13, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 REGENXBIO Inc. (Exact name of registrant as specified in its charter)

| Delaware                                                      | 47-1851754                         |
| (State or other jurisdiction ofincorporation or organization) | -I.R.S. EmployerIdentification No. |
| 9804 Medical Center DriveRockville, Maryland 20850            |                                    |
| (Address of Principal Executive Offices and Zip Code)         |                                    |

REGENXBIO INC. 2025 Equity Incentive Plan (Full title of the plans) Mitchell Chan Chief Financial Officer REGENXBIO Inc. 9804 Medical Center Drive Rockville, Maryland 20850 (Name and address of agent for service) (240) 552-8181 (Telephone number, including area code, of agent for service) Copies to:

| Kerry Shannon Burke     | Patrick J. Christmas      |
| Matthew C. Franker      | EVP, Chief Legal Officer  |
| Covington & Burling LLP | REGENXBIO Inc.            |
| One CityCenter          | 9804 Medical Center Drive |
| 850 Tenth Street, N.W.  | Rockville, Maryland 20850 |
| Washington, D.C. 20001  | (240) 552-8181            |
| (202) 662-6000          |                           |

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b‑2 of the Exchange Act.

| Large accelerated filer |  | Accelerated filer         |  |
| Non-accelerated filer   |  | Smaller reporting company |  |
|                        |  | Emerging growth company   |  |

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a