Company: JUNS
Filing Date: 2025-03-28
Form Type: 10-K
Source: 0001641172-25-001261
Chunk: 1780

Company: JUPITER NEUROSCIENCES, INC.
Filing Date: 2025-03-28
Form: 10-K
Item: Item 8
Chunk 1780
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disease genes and identified several others as leader of the Cure Alzheimer’s Fund Alzheimer’s Genome Project. He also co-discovered
the Wilson’s disease gene and several other neurological disease genes. Most recently, he and his team used Alzheimer’s genes
and human stem cells to create what the New York Times coined, “Alzheimer’s-in-a-Dish”. This is a three-dimensional
human stem cell-derived neural culture system that is considered to be the first true model of Alzheimer’s disease, recapitulating
both pathological hallmarks of Alzheimer’s disease: plaques and tangles. The model has made drug screening for Alzheimer’s
disease 10 times cheaper and 10 times faster. Dr. Tanzi has developed novel therapeutics for Alzheimer’s disease including gamma
secretase modulators and metal chaperones (PBT; Prana) aimed at lowering plaque and tangle pathology. Both have been entered into clinical
trials for Alzheimer’s patients. Dr. Tanzi is also very active in the areas of integrative medicine and applications to brain health.
In this regard, along with Dr. Deepak Chopra, Dr. Tanzi co-directs the Self-Directed Biological Transformation Initiative (SBTI) aimed
at exploring and quantifying the effects of lifestyle interventions on neuroplasticity and epigenetics.

Dr.
Tanzi has published over 500 research papers and has received the highest awards in his field, including the Metropolitan Life Foundation
Award, Potamkin Prize, Ronald Reagan Award, Silver Innovator Award, and many others. He was named to TIME magazine’s 2015 list
of TIME100 Most Influential People in the World, and received the Smithsonian American Ingenuity Award, the top national award for invention
and innovation. He co-authored the popular trade books “Decoding Darkness”, New York Times best seller, “Super Brain”,
and international best seller “Super Genes” with Dr. Deepak Chopra. He was named by GQ magazine as a Rock Star of Science,
and in his spare time, has played keyboards with the band Aerosmith. With singer, Chris Mann, he also composed the beautiful ballad,
“Remember Me”, which honors Alzheimer’s patients, and is being used to raise funds for Alzheimer’s research at
the Cure Alzheimer’s Fund, for which, Dr. Tanzi serves as Chair of the Cure Alzheimer’s Fund Research Consortium.

Li-Huei
Tsai, Ph.D. Dr. Tsai has served as a member of our Scientific