Company: BDRX
Filing Date: 2025-12-11
Form Type: F-1/A
Source: 0001214659-25-017944
Chunk: 127

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-12-11
Form: F-1/A
Chunk 127
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 the laws of the United States or any state thereof or the District of Columbia; |

| · | an estate the income of which is subject to United States federal income taxation regardless of its source; 
 or                                                                                                          |

| · | a trust if (a) a court within the United States is able to exercise primary supervision over the administration                            
 of the trust and one or more United States persons have the authority to control all substantial decisions of the trust, or (b) such trust 
 has a valid election in effect under applicable United States Treasury regulations to be treated as a United States person.                |

| 77 |

For U.S. federal income tax purposes, a beneficial owner ofDepositary Shares generally will be treated as the owner of the underlying Ordinary Shares represented by suchDepositary Shares. Accordingly, deposits or withdrawals of the underlying Ordinary Shares forDepositary Shares generally will not be subject toUnited States federal income tax. The discussion below assumes that the representations contained in the deposit agreement are true and that the obligations in the deposit agreement and any related agreement will be complied with in accordance with their terms. TheUnited States Treasury has expressed concerns that parties to whomDepositary Shares are released before shares are delivered to the depositary or intermediaries in the chain of ownership between the U.S. Holder of a Depositary Share and the issuer of the
security underlying the Depositary Share may be taking actions that are inconsistent with the claiming of foreign tax credits by U.S.
Holders of Depositary Shares. These actions would also be inconsistent with the claiming of the reduced rate of tax, described below,
applicable to dividends received by certain noncorporate U.S. Holders. As a result, the creditability of non-U.S. withholding
taxes (if any), and the availability of the reduced tax rate for dividends received by certain non-corporate U.S. Holders, each
described below, could be affected by actions taken by such parties or intermediaries. Accordingly, U.S. persons considering an investment
in Depositary Shares or Pre-Funded Warrants that, as described below, are generally taxed in the same manner as a U.S. Holder
of Depositary Shares, should consult their own tax advisors as to the particular tax consequences applicable to them relating to the purchase,
ownership and disposition of Depositary Shares or Pre-Funded Warrants, including the applicability of United States federal,
state and local tax laws and non-United States tax laws.

You are urged to consult your tax advisors about the application of