Company: SCLXW
Filing Date: 2025-02-26
Form Type: PRER14A
Source: 0001193125-25-036730
Chunk: 41

Company: Scilex Holding Co
Filing Date: 2025-02-26
Form: PRER14A
Chunk 41
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 Scilex Holding Company, 960 San Antonio Road, Palo Alto, CA 94303. Stockholders who currently receive multiple copies of proxy materials at their addresses and would like to request “householding” of their communications should contact their brokers. WHERE YOU CAN FIND ADDITIONAL INFORMATION We have filed reports, proxy statements and other information with the SEC. The SEC maintains a website that contains the reports, proxy statements and other information we file electronically with the SEC. The address of the SEC website is http://www.sec.gov. You may request, and we will provide at no cost, a copy of these filings, including any exhibits to such filings, by writing or telephoning us at the following address: Corporate Secretary at Scilex Holding Company, 960 San Antonio Road, Palo Alto, CA 94303. You may also access these filings at our website under the investor relations link at https://www.scilexholding.com/investors/overview. OTHER MATTERS Our Board does not know of any other matters to be presented at the Special Meeting. If any additional matters are properly presented at the Special Meeting, the persons named in the enclosed proxy card will have discretion to vote shares they represent in accordance with their own judgment on such matters. It is important that your shares be represented at the Special Meeting, regardless of the number of shares that you hold. You are, therefore, urged to vote by using the Internet as instructed on the enclosed proxy card or execute and return, at your earliest convenience, the enclosed proxy card in the envelope that has also been provided.

| THE BOARD OF DIRECTORS                          |
| Jaisim Shah                                     |
| Chief Executive Officer, President and Director |
| Palo Alto, CA                                   |
| , 2025                                          |

26

APPENDIX A CERTIFICATE OF AMENDMENT TO THE RESTATED CERTIFICATE OF INCORPORATION OF SCILEX HOLDING COMPANY Scilex Holding Company, a corporation organized and existing under the laws of the State of Delaware (the “ Corporation”), does hereby certify that:

| B. | This Certificate of Amendment to the Restated Certificate of Incorporation was adopted in accordance with                               
 Section 242 of the General Corporation Law of the State of Delaware, and has been duly approved by the stockholders of the Corporation. |

| C. | Article IV of the Restated Certificate of Incorporation is hereby further amended to add the following as 
 paragraph D:                                                                                              |

“D. Effective upon the effectiveness of the filing of this Certificate of Amendment to the