Company: TAK
Filing Date: 2025-10-30
Form Type: 6-K
Source: 0001395064-25-000154
Chunk: 36

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-10-30
Form: 6-K
Chunk 36
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akeda calculated income tax expenses for the six-month period ended September 30, 2025, based on the estimated average annual effective tax rate.

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Translation for reference purpose only

#### 4. Operating Segment and Revenue Information
Takeda comprises a single operating segment and is engaged in the research, development, manufacturing, marketing and out-licensing of pharmaceutical products. This is consistent with how the financial information is viewed in allocating resources, measuring performance, and forecasting future periods by the CEO who is Takeda’s Chief Operating Decision Maker.

(1) Disaggregation of Revenue Information

Takeda’s revenue from contracts with customers is comprised of the following:

Revenue by Type of Good or Service

|                                  |     | JPY (millions)                       
 Six-month Period Ended September 30, |      2024 |     |     |      2025 |
|:---------------------------------|:----|:-------------------------------------|----------:|:----|:----|----------:|
| Sales of pharmaceutical products |     |                                      | 2,346,444 |     |     | 2,183,456 |
| Out-licensing and service income |     |                                      |    37,584 |     |     |    36,025 |
| Total                            |     |                                      | 2,384,028 |     |     | 2,219,481 |

Revenue by Business Area and Product

|                           |     | JPY (millions)                       
 Six-month Period Ended September 30, |    2024 |     |     |    2025 |
|:--------------------------|:----|:-------------------------------------|--------:|:----|:----|--------:|
| Gastroenterology:         |     |                                      |         |     |     |         |
| ENTYVIO                   |     |                                      | 473,222 |     |     | 479,235 |
| GATTEX/REVESTIVE          |     |                                      |  73,271 |     |     |  71,641 |
| TAKECAB/VOCINTI*          |     |                                      |  64,301 |     |     |  68,948 |
| DEXILANT                  |     |                                      |  19,833 |     |     |  16,374 |
| EOHILIA                   |     |                                      |   2,251