Company: NCNA
Filing Date: 2025-04-04
Form Type: DRS
Source: 0000950123-25-003335
Chunk: 67

Company: NuCana plc
Filing Date: 2025-04-04
Form: DRS
Chunk 67
---
 including any voting rights.

Waivers and Amendments

The Series B Warrants may be modified or amended, or the provisions thereof waived with the written consent of us and the respective
holder.

Pre-FundedWarrants

The following description of the Pre-Funded Warrants we are offering is a summary and is qualified in
its entirety by reference to the provisions of the Pre-Funded Warrants, the form of which will be filed as an exhibit to the Registration Statement on Form F-1 of which
this prospectus forms a part.

Duration and Exercise Price

Each Pre-Funded Warrant offered hereby will have an initial exercise price per share equal to
$ . The Pre-Funded Warrants are exercisable at any time after the date of issuance until exercised in full and they do not expire. The Pre-Funded Warrants
will be issued in certificated form.

Exercisability

The Pre-Funded Warrants will be exercisable, at the option of the holder, in whole or in part, by
delivering to us a duly executed exercise notice accompanied by payment in full for the number of ADSs purchased upon such exercise (except in the case of a cashless exercise, as discussed below). A holder (together with its affiliates) may not
exercise any portion of the Pre-Funded Warrants to the extent that the holder would own more than 4.99% (or, at the election of the holder, 9.99%) of the outstanding ordinary shares immediately after
exercise. However, upon notice from the holder to us, the holder may decrease or increase the holder’s beneficial ownership limitation, which may not exceed 9.99% of the number of outstanding ordinary shares immediately after giving effect to
the exercise, as such percentage ownership is determined in accordance with the terms of the Pre-Funded Warrants, provided that any increase in the beneficial ownership limitation will not take
effect until 61 days following notice to us. Purchasers in this offering may also elect, prior to the issuance of the Pre-Funded Warrants, to have the initial exercise limitation set at 9.99% of our
outstanding ordinary shares. No fractional ADSs will be issued in connection with the exercise of a Pre-Funded Warrants. In lieu of fractional ADSs, we will either pay the holder an amount in cash equal
to the fractional amount multiplied by the exercise price or round up to the next whole ADS.

Cashless Exercise

At the time a holder exercises its Pre-F