Company: APM
Filing Date: 2025-01-03
Form Type: 424B5
Source: 0001213900-25-000606
Chunk: 19

Company: Aptorum Group Ltd
Filing Date: 2025-01-03
Form: 424B5
Chunk 19
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 ordinary shares is listed on the Nasdaq
Capital Market under the symbol “APM.”

We expect that delivery of the Class A Ordinary
Shares being offered pursuant to this prospectus supplement and the accompanying prospectus will be made on or about January 3, 2025,
subject to customary closing conditions.

Listing

Our Class A Ordinary Shares
are listed on the NASDAQ Capital Market under the symbol “APM”.

<div align='center'>S-12

LEGAL MATTERS</div>

Certain legal matters governed
by the laws of the Cayman Islands with respect to the validity of the offered securities will be passed upon for us by Campbells. Certain
legal matters governed by the laws of New York will be passed upon for us by Hunter Taubman Fischer & Li, LLC, New York, New York.
Ellenoff Grossman & Schole LLP, New York, New York, is counsel to Maxim Group LLC in connection with this offering.

<div align='center'>EXPERTS</div>

The consolidated financial
statements of our Company appearing in our annual report on Form 20-F for the fiscal years ended December 31, 2023 and 2022 have been
audited by Marcum Asia CPAs LLP, an independent registered public accounting firm, as set forth in the reports thereon included therein
and incorporated herein by reference. Such consolidated financial statements are incorporated herein by reference in reliance upon such
reports given on the authority of such firms as experts in accounting and auditing.

<div align='center'>S-13

INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE</div>

The SEC allows us to “incorporate
by reference” into this prospectus the information we file with the SEC. This means that we can disclose important information to
you by referring you to those documents. Any statement contained in a document incorporated by reference in this prospectus shall be deemed
to be modified or superseded for purposes of this prospectus to the extent that a statement contained herein, or in any subsequently filed
document, which also is incorporated by reference herein, modifies or supersedes such earlier statement. Any such statement so modified
or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this prospectus.

We hereby incorporate by reference
into this prospectus the following documents that we have filed with the SEC under the Exchange Act:

| ● 
 ● | the Company’s                                                                                                                      
 Annual Report on Form 20-F for the