Company: BDRX
Filing Date: 2025-05-12
Form Type: 424B3
Source: 0001214659-25-007341
Chunk: 1

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-05-12
Form: 424B3
Chunk 1
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Plan of Distribution.”

Our Depositary Shares are
listed on the NASDAQ Capital Market under the symbol “BDRX.” The last reported closing price of our Depositary Shares on the
NASDAQ Capital Market on May 8, 2025 was $1.40.

Investing in our securities involves risks. See “Risk Factors” beginning on page 9 of this prospectus for a discussion of the factors you should carefully consider before deciding to purchase these securities.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

<div align='center'>The date of this prospectus is May 9, 2025</div>

<div align='center'>TABLE OF CONTENTS</div>

|                                                      | Page |
| ABOUT THIS PROSPECTUS                                |    1 |
| PRESENTATION OF FINANCIAL AND OTHER INFORMATION      |    2 |
| PROSPECTUS SUMMARY                                   |    4 |
| RISK FACTORS                                         |    9 |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS |   10 |
| USE OF PROCEEDS                                      |   12 |
| DIVIDEND POLICY                                      |   13 |
| CAPITALIZATION                                       |   14 |
| DESCRIPTION OF OFFERED SECURITIES AND SHARE CAPITAL  |   15 |
| DESCRIPTION OF AMERICAN DEPOSITARY SHARES            |   43 |
| TAXATION                                             |   61 |
| SELLING SHAREHOLDERS                                 |   70 |
| PLAN OF DISTRIBUTION                                 |   74 |
| EXPENSES OF THE OFFERING                             |   76 |
| LEGAL MATTERS                                        |   76 |
| EXPERTS                                              |   76 |
| ENFORCEMENT OF CIVIL LIABILITIES                     |   76 |
| WHERE YOU CAN FIND MORE INFORMATION                  |   77 |

| i |

<div align='center'>ABOUT THIS PROSPECTUS</div>

This prospectus is part of
a registration statement that we filed with the Securities and Exchange Commission, or SEC. As permitted by the rules and regulations
of the SEC, the registration statement filed by us includes additional information not contained in this prospectus. You may read the
registration statement and the other reports we file with the SEC at the SEC’s website or its offices described below under the
heading “Where You Can Find