Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 202

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 202
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 The decrease in general and administrative fees was primary due to the reversal
of deferred cash bonus payables to employees and reduction of employees during current period. The reversal was due to the Group’s
agreements with employees to discharge the Group’s obligation to settle their outstanding deferred cash bonus payables from previous
years in exchange of fully vested ordinary shares.

|                                       |     |   |   Year Ended 
 December 31, 
         2023 |     |   |   Year Ended 
 December 31, 
         2022 |
|:--------------------------------------|:----|:--|-------------:|:----|:--|-------------:|
| General and Administrative Fees:      |     |   |              |     |   |              |
| Payroll expenses                      |     | $ |      893,437 |     | $ |    3,793,367 |
| Rent and rates                        |     |   |      213,701 |     |   |      265,558 |
| Travelling expenses                   |     |   |       59,874 |     |   |      158,357 |
| Amortization and depreciation         |     |   |       53,799 |     |   |      143,498 |
| Insurance                             |     |   |      474,746 |     |   |      546,675 |
| Advertising and marketing expenses    |     |   |       48,982 |     |   |       98,082 |
| Other expenses                        |     |   |      186,098 |     |   |      214,868 |
| Total General and Administrative Fees |     | $ |    1,930,637 |     | $ |    5,220,405 |

Legal and professional fees

For the years ended December 31, 2023, and 2022, the legal and professional
fees were $2,538,161 and $2,888,140, respectively. The decrease in legal and professional fees was mainly due to less consulting services
engaged during 2023 as a consequence of exclusive emphasis on its lead projects and suspension of non-lead projects.

Other operating expenses

For the years ended December 31, 2023, and 2022, the other operating
expenses was $1,067,690 and $261,038, respectively. The increase in other operating expenses was primarily due to impairment losses of
long-lived assets during current