Company: RCUS
Filing Date: 2025-04-22
Form Type: DEF 14A
Source: 0001724521-25-000052
Chunk: 2

Company: Arcus Biosciences, Inc.
Filing Date: 2025-04-22
Form: DEF 14A
Chunk 2
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### PROXY STATEMENT

### FOR THE ANNUAL MEETING OF STOCKHOLDERS

#### TO BE HELD ON JUNE 10, 2025
<div align='center'>To be held virtually at www.virtualshareholdermeeting.com/RCUS2025

on Tuesday, June 10, 2025 at 8:30 am Pacific time</div>

### IMPORTANT NOTICE REGARDING THE INTERNET AVAILABILITY OF PROXY MATERIALS
<div align='center'>FOR THE ANNUAL MEETING OF STOCKHOLDERS TO BE HELD ON JUNE 10, 2025</div>

This proxy statement and our annual report are available on our website at www.proxyvote.com. We intend to mail the Notice of Internet Availability of Proxy Materials on or about April 24, 2025 to all stockholders of record entitled to vote at the Annual Meeting.

| MEETING AGENDA |     |                                                                                                                                                                                                           |     |                                 |
| Proposal No.   |     | Proposal                                                                                                                                                                                                  |     | Board Vote                      
 Recommendation                  |
| 1              |     | To elect the Board of Directors’ four nominees to hold office as Class I directors until the 2028 Annual Meeting of Stockholders and until their successors are duly elected and qualified.               |     | For each Arcus director nominee |
| 2              |     | To ratify the selection by the Audit Committee of the Board of Directors of Ernst & Young LLP as the independent registered public accounting firm of Arcus for its fiscal year ending December 31, 2025. |     | For                             |
| 3              |     | To approve, on an advisory basis, the compensation of Arcus’s named executive officers, as disclosed in this Proxy Statement.                                                                             |     | For                             |

#### Table of Contents
|                                                                                         |     |                                                             |     |    |     | Page |
| QUESTIONS AND ANSWERS ABOUT THESE PROXY MATERIALS AND VOTING                            |     |                                                             |     |  1 |     |      |
| PROPOSAL 1 ELECTION OF DIRECTORS                                                        |     |                                                             |     |  7 |     |      |
|                                                                                         |     | Director Nominees                                           |     |  8 |     |      |
|                                                                                         |     | Other Directors                                             |     |  9 |     |      |
|                                                                                         |     | Director Diversity                                          |     | 11 |     |      |
| CORPOR