Company: RPTX
Filing Date: 2025-04-29
Form Type: DEF 14A
Source: 0001193125-25-103764
Chunk: 69

Company: Repare Therapeutics Inc.
Filing Date: 2025-04-29
Form: DEF 14A
Chunk 69
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 that the rendering of services other than audit services by Ernst & Young LLP is compatible with maintaining the principal accountant’s independence.

<div align='center'>OUR BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” THE APPOINTMENT OF ERNST& YOUNG LLP AS OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM AND AUTHORIZATION OF THE BOARD TO FIX ERNST& YOUNG LLP’S REMUNERATION.

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SECURITY OWNERSHIP OF CERTAIN BENEFICAL OWNERS AND MANAGEMENT The following table sets forth certain information regarding the ownership of our common shares as of April 15, 2025 by:

| • |     | each person or entity known by us to be beneficial owners of more than five percent of our common shares; |

| • |     | each of our current directors and director nominees; |

| • |     | each of our named executive officers; and |

| • |     | all of our current executive officers and directors as a group. |

We have determined beneficial ownership in accordance with the rules of the SEC. Under these rules, beneficial ownership includes any common shares as to which the individual or entity has sole or shared voting power or investment power. In computing the number of shares beneficially owned by an individual or entity and the percentage ownership of that person, common shares subject to options held by such person that are currently exercisable or will become exercisable within 60 days of April 15, 2025 are considered outstanding, although these shares are not considered outstanding for purposes of computing the percentage ownership of any other person. Unless noted otherwise, the address of all listed shareholders is c/o Repare Therapeutics Inc., 7171 Frederick-Banting, Building 2, Suite 270, St-Laurent,Québec, Canada H4S 1Z9.

| Beneficial Owner                                                         |           | Beneficial Ownership(1) |            |     |            |     |      |   |
|                                                                          | Number of 
 Shares    |                         |            |     | Percent of 
 Total      |     |      |   |
| Greater than 5% Shareholders                                             |           |                         |            |     |            |     |      |   |
| Entities affiliated with BVF(2)                                          |           |                         | 10,333,600 |     |            |     | 24.1 | % |
| Blue Owl Capital Holdings(3)                                             |           |                         |  3,372,499 |