Company: APM
Filing Date: 2025-10-14
Form Type: 424B5
Source: 0001213900-25-098635
Chunk: 73

Company: Aptorum Group Ltd
Filing Date: 2025-10-14
Form: 424B5
Chunk 73
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.gov that contains our filed reports and other information that we file electronically with the SEC.

We maintain a corporate website at www.aptorumgroup.com. Information contained on, or that can be accessed through, our website does not constitute a part of this prospectus.

<div align='center'>ENFORCEABILITY OF CIVIL LIABILITIES</div>

We are incorporated under
the laws of the Cayman Islands as an exempted company with limited liability. We incorporated in the Cayman Islands because of certain
benefits associated with being a Cayman Islands corporation, such as political and economic stability, an effective judicial system, a
favorable tax system, the absence of foreign exchange control or currency restrictions and the availability of professional and support
services. However, the Cayman Islands have a less developed body of securities laws that provide significantly less protection to investors
as compared to the securities laws of the United States. In addition, Cayman Islands companies may not have standing to sue before the
federal courts of the United States.

Substantial portion of our
assets are located outside the United States. In addition, some of our directors and officers are residents of jurisdictions other than
the United States and all or a substantial portion of their assets are located outside the United States. As a result, it may be difficult
for investors to effect service of process within the United States upon us or our directors and officers, or to enforce against us or
them judgments obtained in United States courts, including judgments predicated upon the civil liability provisions of the securities
laws of the United States or any state in the United States.

According to our local Cayman
Islands’ counsel, there is uncertainty with regard to Cayman Islands law relating to whether a judgment obtained from the United
States, the United Kingdom or Hong Kong courts under civil liability provisions of the securities laws will be determined by the courts
of the Cayman Islands as penal or punitive in nature. If such a determination is made, the courts of the Cayman Islands will not recognize
or enforce the judgment against a Cayman Islands’ company. The courts of the Cayman Islands in the past determined that disgorgement
proceedings brought at the instance of the Securities and Exchange Commission are penal or punitive in nature and such judgments would
not be enforceable in the Cayman Islands. Other civil liability provisions of the securities laws may be characterized as remedial, and
therefore enforceable but the Cayman Islands’ Courts have not yet ruled in this regard. Our