Company: AZN
Filing Date: 2025-09-29
Form Type: 6-K
Source: 0001104659-25-094039
Chunk: 16

Company: ASTRAZENECA PLC
Filing Date: 2025-09-29
Form: 6-K
Chunk 16
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, their interests in AstraZeneca Shares following the implementation of the Harmonised Listing Structure. The Harmonised Listing Structure and related Settlement System Migration cannot proceed unless the Resolution is approved by 75% of the votes cast (in person or by proxy) by Shareholders at the General Meeting. The Resolution will be decided on a poll.

Further details of the proposed amendments to the Existing Articles are set out in Part V ( Proposed Amendments to the Existing Articles ) of this document. Copies of the proposed New Articles and the Existing Articles, marked up to show the proposed changes, are available for inspection on the National Storage Mechanism at https://data.fca.org.uk/#/nsm/nationalstoragemechanism and on the Company’s website at https://www.astrazeneca.com/investor-relations/shareholder-information.html#2025-0 from the date of this document and will be made available for inspection on the online platform and at the place of the General Meeting for at least 15 minutes before and during the General Meeting.

#### 4.
**Action to be taken in relation to the General Meeting**

As outlined above, implementation of the Harmonised Listing Structure is conditional on the approval by Shareholders of the Resolution. Your vote is very important.

The General Meeting will be a digitally-enabled meeting that is broadcast live to enable all Shareholders, including holders of AstraZeneca ADSs and Swedish Listed Shares, to participate in the General Meeting. The content and presentation of the General Meeting will be optimised for online participation. Shareholders who plan to attend the General Meeting are therefore strongly encouraged to join via the online platform, which can be found at:

#### https://meetings.lumiconnect.com/100-392-363-424
A step-by-step guide on how to join the General Meeting electronically from your personal device via the online platform can be found on pages 38 to 39 of this document. Holders of Swedish Listed Shares and AstraZeneca ADSs should instead follow the instructions set out in the notice documents made available to them. Your attention is also drawn to the part of this document entitled “Action to be taken” and the Notes to the Notice of General Meeting which each contain details of how to submit questions, and how to vote, either in advance or during the General Meeting.

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TABLE OF CONTENTS

#### 5.

#### Taxation
Your attention is drawn to Part IV ( Certain Taxation Matters ) of this document for further