Company: CERO
Filing Date: 2025-05-27
Form Type: POS AM
Source: 0001213900-25-047469
Chunk: 2

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-05-27
Form: POS AM
Chunk 2
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 this preliminary prospectus is not complete and may be changed. These securities may not be issued until the registration statement filed with the U.S. Securities and Exchange Commission is effective. This preliminary prospectus is not an offer to sell these securities and does not constitute the solicitation of an offer to buy these securities in any jurisdiction where the offer or sale is not permitted. SUBJECT TO COMPLETION, DATED MAY 23, 2025 PRELIMINARY PROSPECTUS CERO THERAPEUTICS HOLDINGS, INC. Up to 2,100,000 Shares of Common Stock This prospectus relates to the potential offer and sale from time to time by Keystone Capital Partners, LLC (“Keystone”) of up to 2,100,000 shares of common stock, par value $0.0001 per share (the “Common Stock”), that have been or may be issued by us to Keystone, including (i) 2,086,357 shares of Common Stock that we may elect, in our sole discretion, to issue and sell to Keystone, from time to time from and after the Keystone Commencement Date (as defined below) pursuant to a Common Stock Purchase Agreement, dated as of November 8, 2024, by and between us and Keystone (the “November 2024 Keystone Purchase Agreement”) and (ii) 13,643 shares of Common Stock that have been issued to Keystone pursuant to a Common Stock Purchase Agreement, dated as of February 14, 2024, by and between us and Keystone (the “February 2024 Keystone Purchase Agreement” and, together with the November 2024 Keystone Purchase Agreement, the “Keystone Purchase Agreements”), as consideration for it establishing an equity line of credit (the “Keystone Equity Financing”). As of the date of this prospectus, pursuant to the Prior Registration Statement (as defined below), we have issued and sold 233,779 shares of Common Stock (the “February 2024 Keystone Purchase Shares”) for aggregate proceeds of $4,410,616 under the Keystone Equity Financing. We previously filed a registration statement on Form S-1 (File No. 333-278603), which was declared effective by the SEC on May 1, 2024, and remains in effect (the “Prior Registration Statement”), with respect to up to (i) 250,000 Keystone Purchase Shares and (ii) 6,190 Keystone Commitment Shares. As of the date of this prospectus, we have issued and