Company: XXII
Filing Date: 2025-02-05
Form Type: S-3/A
Source: 0001493152-25-005039
Chunk: 16

Company: 22nd Century Group, Inc.
Filing Date: 2025-02-05
Form: S-3/A
Chunk 16
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, Inc.(2)   |     |                         | 20,825 |     |                                              | 20,825 |     |                                                       | - |     | *                                   |

* Less than 1%.

| (1) | Erin C. Delehanty controls                                                                                                               
 the selling stockholder and, accordingly, may be deemed to have voting and dispositive power with respect to the shares held by this     
 selling securityholder. The address of the foregoing individual and entity is c/o North Carolina State University,                       
 1210 Varsity Drive, Suite 202, Raleigh NC 27695. Since 1998, the Company has been party to multiple research and development agreements  
 with North Carolina State University, resulting in exclusive licenses to various patented technologies. The license agreements generally 
 entail obtaining an exclusive option or license agreement to any invention arising out of the Company’s funded research. In all          
 such cases, the Company funds and controls all patent filings as the exclusive licensee. Our Annual Report on Form 10-K for the year     
 ended December 31, 2023 and subsequently filed Quarterly Reports on Form 10-Q provide additional information about our agreements with   
 North Carolina State University.                                                                                                         |
| (2) | John Ing controls the selling stockholder and, accordingly, may be deemed to have voting and dispositive                                 
 power with respect to the shares held by this selling securityholder. The address of the foregoing individual and entity is c/o Maison   
 Placements Canada, Inc., 130 Adelaide Street West, Suite 2116, Toronto, Ontario M5H 3P5.                                                 |

| 8 |

<div align='center'>Plan of Distribution</div>

We are registering shares of common stock to permit the resale of these shares of common stock by the selling stockholders from time to time after the date of this prospectus. We will not receive any of the proceeds from the sale by the selling stockholders of the shares of common stock. We will bear all fees and expenses incident to the registration of the shares of common stock, provided, however, the selling stockholders will pay all underwriting discounts and selling commissions, if any.

The selling stockholders may sell all or a portion of the shares of common stock held and offered hereby from time to time directly or through one or more underwriters, broker-dealers or agents. If the shares of common stock are sold through underwriters or broker-dealers, the selling stockholders will be responsible for underwriting discounts or commissions or agent’s commissions.