Company: JUNS
Filing Date: 2025-03-28
Form Type: 10-K
Source: 0001641172-25-001261
Chunk: 203

Company: JUPITER NEUROSCIENCES, INC.
Filing Date: 2025-03-28
Form: 10-K
Item: Item 9C
Chunk 203
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his B.S. (microbiology) and B.A. (history) at the University of Rochester in 1980 and his Ph.D. (neurobiology) at Harvard Medical School
in 1990. In his research achievements, Dr. Tanzi served on the team that was the first to find a disease gene ((Huntington’s disease)
using human genetic markers, helping to launch the field of neurogenetics. He later co-discovered all three early-onset familial Alzheimer’s
disease genes and identified several others as leader of the Cure Alzheimer’s Fund Alzheimer’s Genome Project. He also co-discovered
the Wilson’s disease gene and several other neurological disease genes. Most recently, he and his team used Alzheimer’s genes
and human stem cells to create what the New York Times coined, “Alzheimer’s-in-a-Dish”. This is a three-dimensional
human stem cell-derived neural culture system that is considered to be the first true model of Alzheimer’s disease, recapitulating
both pathological hallmarks of Alzheimer’s disease: plaques and tangles. The model has made drug screening for Alzheimer’s
disease 10 times cheaper and 10 times faster. Dr. Tanzi has developed novel therapeutics for Alzheimer’s disease including gamma
secretase modulators and metal chaperones (PBT; Prana) aimed at lowering plaque and tangle pathology. Both have been entered into clinical
trials for Alzheimer’s patients. Dr. Tanzi is also very active in the areas of integrative medicine and applications to brain health.
In this regard, along with Dr. Deepak Chopra, Dr. Tanzi co-directs the Self-Directed Biological Transformation Initiative (SBTI) aimed
at exploring and quantifying the effects of lifestyle interventions on neuroplasticity and epigenetics.

Dr.
Tanzi has published over 500 research papers and has received the highest awards in his field, including the Metropolitan Life Foundation
Award, Potamkin Prize, Ronald Reagan Award, Silver Innovator Award, and many others. He was named to TIME magazine’s 2015 list
of TIME100 Most Influential People in the World, and received the Smithsonian American Ingenuity Award, the top national award for invention
and innovation. He co-authored the popular trade books “Decoding Darkness”, New York Times best seller, “Super Brain”,
and international best seller “Super Genes” with Dr. Deepak Chopra. He was named by GQ magazine as a Rock Star