Company: HCTI
Filing Date: 2025-11-19
Form Type: 424B5
Source: 0001213900-25-112544
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Company: Healthcare Triangle, Inc.
Filing Date: 2025-11-19
Form: 424B5
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Filed pursuant to Rule 424(b)(5)

Registration Statement No. 333-276382

Prospectus Supplement

(To Prospectus dated January 31, 2024)

<div align='center'>Up to $20,000,000

Healthcare Triangle, Inc.

Common Stock</div>

We may offer to sell up to $20,000,000
in the aggregate of our shares of common stock, $0.00001 per share from time to time pursuant to this prospectus supplement through Spartan
Capital Securities, LLC, which we refer to as the Sales Agent, pursuant to a Sales Agreement, dated November 18, 2025 (the “ATM
Sales Agreement”).

Our common stock trades on the Nasdaq
Capital Market (“Nasdaq”) under the symbol “HCTI.” The last reported sale price of our common stock on Nasdaq
on November 14, 2025 was $2.09 per share.

Shares of our common stock covered by
this prospectus may be sold by any method deemed to be an “at the market offering” as defined in Rule 415(a)(4) under the
Securities Act of 1933, as amended (the “Securities Act”). When it receives a sale order from us, the Sales Agent has agreed
to use commercially reasonable efforts consistent with its normal trading and sales practices to execute the order on mutually agreed
terms. There is no arrangement for funds to be received in any escrow, trust, or similar arrangement.

The Sales Agent will be entitled to cash
compensation at a fixed commission rate of 3% of the gross sales price per share sold through it under the ATM Sales Agreement.
In connection with the sale of our common stock on our behalf, the Sales Agent will be deemed to be an “underwriter” within
the meaning of the Securities Act and the compensation of the Sales Agent will be deemed to be underwriting commissions or discounts.
See “Plan of Distribution” beginning on page S-10 for additional information regarding the Sales Agent’s compensation.
We have also agreed to provide indemnification and contribution to the Sales Agent with respect to certain liabilities, including liabilities
under the Securities Act. Unless earlier terminated by us or the Sales Agent pursuant to the terms of the ATM Sales Agreement, this
offering pursuant to this prospectus supplement will automatically terminate upon the earlier of (1) the sale of common stock pursuant
to this prospectus supplement having an aggregate sales price of $20,000