Company: CERO
Filing Date: 2025-08-11
Form Type: S-3
Source: 0001213900-25-073849
Chunk: 37

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-08-11
Form: S-3
Chunk 37
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 persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the      
 SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that      
 a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director,    
 officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director,    
 officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel   
 the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification 
 by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.               |

<div align='center'>II-6

SIGNATURES</div>

Pursuant to the requirements
of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements
for filing on Form S-3 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized,
in the city of South San Francisco, State of California, on the 8th day of August 2025.

| CERO THERAPEUTICS 
 HOLDINGS, INC.    |                         |
| By:               | /s/                     
 Chris Ehrlich           |
|                   | Chris Ehrlich           |
|                   | Chairman,               
 Chief Executive Officer |
|                   | and Director            |
|                   | -Principal              
 Executive Officer       |

<div align='center'>POWER OF ATTORNEY</div>

KNOW ALL PERSONS BY THESE
PRESENTS, that each person whose signature appears below constitutes and appoints each of Chris Ehrlich and Andrew Kucharchuk as his or
her true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him or her and in his or her name,
place and stead, in any and all capacities, to sign one or more registration statements on Form S-3 and any and all amendments to such
registration statements, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the United
States Securities and Exchange Commission, granting unto said attorneys-in-f