Company: SNY
Filing Date: 2025-03-27
Form Type: S-8
Source: 0001193125-25-065210
Chunk: 4

Company: Sanofi
Filing Date: 2025-03-27
Form: S-8
Chunk 4
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 Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in Paris, France on March 27, 2025.

| SANOFI |     |                         |
| By:    |     | /s/ Paul Hudson         |
| Name:  |     | Paul Hudson             |
| Title: |     | Chief Executive Officer |

POWER OF ATTORNEY KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below hereby severally constitutes and appoints Paul Hudson, François-XavierRoger, Roy Papatheodorou and Olivier Klaric, and each of them singly, as such person’s true and lawful attorney-in-factand agent, with full power of substitution and resubstitution, for such person and in such person’s name, place and stead, in any and all such capacities, to sign the registration statement on Form S-8(the “Registration Statement”) to be filed by Sanofi (the “Registrant”) in connection with the Action 2025 Shareholding Plan, and any and all amendments and post-effective amendments thereto and any and all other documents that may be required in connection therewith, with the United States Securities and Exchange Commission (the “Commission”), and any registration statement filed by the Registrant pursuant to Rule 462(b) under the Securities Act of 1933, as amended, which relates to the Registration Statement, and to file any of the same with the Commission. Each of said attorneys shall have power to act with or without the others, and shall have full power and authority to do and perform, in the name and on behalf of each such officer and director of the Registrant who shall have executed this Power of Attorney, every act whatsoever which such attorneys, or any one of them, may deem necessary or desirable to be done in connection therewith as fully and to all intents and purposes as such officer or director of the Registrant might or could do in person. Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities indicated on March 27, 2025.

| Signatures                |     | Title                                           |
| /s/ Frédéric Oudéa        
 Frédéric Oudéa            |     | Chairman of the Board of Directors              |
| /s/ Paul Hudson           
 Paul Hudson               |     | Chief Executive Officer and Director (Principal 
 Executive Officer)                              |
| /s/ François-Xavier Roger