Company: RNLXY
Filing Date: 2025-07-30
Form Type: 424B3
Source: 0001193805-25-001128
Chunk: 28

Company: Renalytix plc
Filing Date: 2025-07-30
Form: 424B3
Chunk 28
---
 the voting instructions received from the Holder of the ADSs. If the Depositary
does not receive voting instructions from a Holder as of the ADS Record Date on or before the date established by the Depositary for such
purpose, such Holder shall be deemed, and the Depositary shall deem such Holder, to have instructed the Depositary to give a discretionary
proxy to a person designated by the Company to vote the Deposited Securities; provided, however, that no such discretionary proxy
shall be given by the Depositary with respect to any matter to be voted upon as to which the Company informs the Depositary that (i) the
Company does not wish such proxy to be given, (ii) substantial opposition exists, or (iii) the rights of holders of Deposited Securities
may be adversely affected.

Deposited Securities represented
by ADSs for which no timely voting instructions are received by the Depositary from the Holder shall not be voted (except as otherwise
contemplated herein). Neither the Depositary nor the Custodian shall under any circumstances exercise any discretion as to voting and
neither the Depositary nor the Custodian shall vote, attempt to exercise the right to vote, or in any way make use of, for purposes of
establishing a quorum or otherwise, the Deposited Securities represented by ADSs, except pursuant to and in accordance with the voting
instructions timely received from Holders or as otherwise contemplated in the Deposit Agreement or herein. If the Depositary timely receives
voting instructions from a Holder which fail to specify the manner in which the Depositary is to vote the Deposited Securities represented
by such Holder’s ADSs, the Depositary will deem such Holder (unless otherwise specified in the notice distributed to Holders) to
have instructed the Depositary to vote in favor of the items set forth in such voting instructions.

Notwithstanding anything
else contained herein, the Depositary shall, if so requested in writing by the Company, represent all Deposited Securities (whether or
not voting instructions have been received in respect of such Deposited Securities from Holders as of the ADS Record Date) for the sole
purpose of establishing quorum at a meeting of shareholders.

Notwithstanding anything
else contained in the Deposit Agreement or this ADR, the Depositary shall not have any obligation to take any action with respect to any
meeting, or solicitation of consents or proxies, of holders of Deposited Securities if the taking of such action would violate U.S. or
English laws. The