Company: TAK
Filing Date: 2025-07-30
Form Type: 6-K
Source: 0001395064-25-000120
Chunk: 2

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-07-30
Form: 6-K
Chunk 2
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The definition of Constant Exchange Rate change is stated in “Definition and Explanation of Non-IFRS Measures and U.S. Dollar Convenience Translations” in the Financial Appendix.

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#### Additional Information
| (1) Significant changes in the scope of consolidation during the period             |     | : No |     |                      |
| (2) Changes in accounting policies and changes in accounting estimates              |     |      |     |                      |
| 1) Changes in accounting policies required by IFRS                                  |     | : No |     |                      |
| 2) Changes in accounting policies other than 1)                                     |     | : No |     |                      |
| 3) Changes in accounting estimates                                                  |     | : No |     |                      |
| (3) Number of shares outstanding (common stock)                                     |     |      |     |                      |
| 1) Number of shares outstanding (including treasury stock) at period end:           |     |      |     |                      |
| June 30, 2025                                                                       |     |      |     | 1,590,962,609 shares |
| March 31, 2025                                                                      |     |      |     | 1,590,949,609 shares |
| 2) Number of shares of treasury stock at period end:                                |     |      |     |                      |
| June 30, 2025                                                                       |     |      |     | 28,968,756 shares    |
| March 31, 2025                                                                      |     |      |     | 17,299,963 shares    |
| 3) Average number of outstanding shares (for the three-month period ended June 30): |     |      |     |                      |
| June 30, 2025                                                                       |     |      |     | 1,564,729,658 shares |
| June 30, 2024                                                                       |     |      |     | 1,568,915,479 shares |

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Review of the attached condensed interim consolidated financial statements by certified public accountants or an audit firm: No

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Note to ensure appropriate use of forecasts and guidance, and other noteworthy items

| • |     | Takeda applies International Financial Reporting Standards (IFRS), and the disclosure information in this document is based on IFRS. |

| • |     | All forecasts and management guidance in this document are based on information and assumptions currently available to