Company: SHPH
Filing Date: 2025-01-24
Form Type: 424B3
Source: 0001493152-25-003508
Chunk: 201

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-01-24
Form: 424B3
Chunk 201
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ible Notes (now labeled Notes Payable)           |
| ● | Note 7 – Stockholders’ Equity                                    |
| ● | Note 8 – Derivative Liabilities                                  |
| ● | Note 10 – Income Taxes                                           |

| F-27 |

The impact of the errors described above also impact
the Company’s Annual Report on Form 10-K for the years ended December 31, 2023 and December 31, 2022 within additional paid in capital and accumulated deficit, resulting in the preparation and filing of this Annual Report on Form 10-K/A.

Schedule of Error Corrections And Prior Period Adjustments

| Consolidated Balance Sheet as of December 31, 2023 |     | As Reported |             |   |     | Adjustment |            |   |     | As Restated |             |   |
|:---------------------------------------------------|:----|:------------|------------:|:--|:----|:-----------|-----------:|:--|:----|:------------|------------:|:--|
| Additional paid in capital                         |     |             |  19,543,363 |   |     |            |  9,945,692 |   |     |             |  29,489,055 |   |
| Accumulated deficit                                |     |             | (15,487,612 | ) |     |            | (9,945,692 | ) |     |             | (25,433,304 | ) |

Additionally, the Company has provided Note 11 – Quarterly Financial
Data (unaudited and restated) to present the impact of the above restatements on the unaudited quarterly financial information for the
period ended September 30, 2023.

The Company’s prior and updated accounting for
the errors described above do not have any effect on the Company’s previously reported cash or cash flows.

The following tables summarize the effect of the restatement
on each financial statement line item as of the dates indicated:

| Consolidated Balance Sheet as of December 31, 2022 |     | As Reported |            |   |     | Adjustment |            |      |     | As Restated |             |   |
|:---------------------------------------------------|:----|:------------|-----------:|:--|:----|:-----------|-----------:|-----:|:----|:------------|------------:|:--|
| Additional paid in capital                         |     |             | 16,572,741 |