Company: SHPH
Filing Date: 2025-03-06
Form Type: CORRESP
Source: 0001493152-25-009323
Chunk: 0

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-03-06
Form: CORRESP
Chunk 0
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<div align='center'>WestPark Capital, Inc.

1800 Century Park East, Suite 220

Los Angeles, CA 90067</div>

March 6, 2025

Via EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

| Re: | Shuttle                        
 Pharmaceuticals Holdings, Inc. |
|     | Registration                   
 Statement on Form S-1          |
|     | File                           
 No. 333-284889                 |

Acceleration Request

| Requested 
 Date:     | Friday,         
 March 7, 2025   |
|:----------|:----------------|
| Requested 
 Time:     | 4:30            
 PM Eastern Time |

Ladies and Gentlemen:

Pursuant to Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended (the “Securities Act”), WestPark Capital, Inc., as representative of the underwriters of the offering, hereby joins the request of Shuttle Pharmaceuticals Holdings, Inc. that the effective date of the above-referenced Registration Statement on Form S-1 be accelerated so that it may become effective at 4:30 p.m., Eastern Time, on Friday, March 7, 2025, or as soon thereafter as practicable.

Pursuant to Rule 60 of the General Rules and Regulations under the Securities Act, please be advised that there will be distributed to each underwriter or dealer, who is reasonably anticipated to participate in the distribution of the security, as many copies of the proposed form of preliminary prospectus as appears to be reasonable to secure adequate distribution of the preliminary prospectus.

The undersigned confirms that it has complied with and will continue to comply with, and it has been informed or will be informed by participating dealers that they have complied with or will comply with, Rule 15c2-8 promulgated under the Securities Exchange Act of 1934, as amended.

WESTPARK CAPITAL, INC.

| Very         
 truly yours, |                   |
| By:          | /s/               
 Jason Stern       |
| Name:        | Jason             
 Stern             |
| Title:       | Chief             
 Operating Officer |