Company: AZN
Filing Date: 2025-04-29
Form Type: 6-K
Source: 0001654954-25-004737
Chunk: 19

Company: ASTRAZENECA PLC
Filing Date: 2025-04-29
Form: 6-K
Chunk 19
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flow hedge.

Table 14: Currency sensitivities

| Currency | Primary Relevance | Exchange rate vs USD (average rate in period) |           |        |            |        | Annual impact of 5% weakening vs 
                         USD1($m) |                       |
|          |                   |                                      FY 20242 | YTD 20253 | Change 
    (%) | Mar  20254 | Change 
    (%) |                     TotalRevenue | Core Operating Profit |
| EUR      | Total Revenue     |                                          0.92 |      0.95 |     -3 |       0.93 |     -0 |                             -461 |                  -232 |
| CNY      | Total Revenue     |                                          7.21 |      7.29 |     -1 |       7.26 |     -1 |                             -313 |                  -171 |
| JPY      | Total Revenue     |                                        151.46 |    152.59 |     -1 |     149.11 |      2 |                             -179 |                  -121 |
| GBP      | Operating expense |                                          0.78 |      0.79 |     -2 |       0.78 |      1 |                              -68 |                   124 |
| SEK      | Operating expense |                                         10.57 |     10.69 |     -1 |      10.16 |      4 |                               -9 |                    69 |
| Other    |                   |                                               |           |        |            |        |                             -557 |                  -289 |

1. Assumes the average exchange rate vs USD in FY 2025 is 5% lower than the average rate in FY 2024. The impact data are estimates, based on best prevailing assumptions around currency profiles.

2. Based on average daily spot rates 1 Jan 2024 to 31 Dec 2024.

3. Based on average daily spot rates 1 Jan 2025 to 31 Mar 2025.

4. Based on average daily spot rates 1 Mar 2025 to 31 Mar 2025.

| Interim              
 financial statements |

Table 15: Condensed consolidated statement of comprehensive income

|                                                                    | Q1 2025 
      $m | Q1 2024 
      $m |
| - Product Sales                                                    |  12,875 |  12,177 |
| - Alliance Revenue                                                 |     639 |