Company: PSTV
Filing Date: 2025-08-04
Form Type: DRS
Source: 0000950123-25-006916
Chunk: 17

Company: PLUS THERAPEUTICS, INC.
Filing Date: 2025-08-04
Form: DRS
Chunk 17
---

of and subject to satisfaction of the conditions set forth in the Purchase Agreement, we [intend to issue] [1,612,903] shares of our common stock with a per share value of $[0.31] on August 8, 2025 as the Initial Commitment Shares. The Initial
Commitment Shares must be included in a registration statement to be filed with and declared effective by the SEC on or prior to the date the Initial Commitment Fee is due registering under the Securities Act the resale by Lincoln Park of such
Initial Commitment Shares. We have also agreed to pay an Additional Commitment Fee of $500,000, which we may elect to pay in cash, shares of our common stock or any combination thereof, upon our receipt of $25.0 million aggregate gross proceeds
from sales of common stock to Lincoln Park under the Purchase Agreement. Through August [●], 2025, approximately $[2.8] million of common stock have been sold under the Prior Registration Statement. In the event that part or all of the

8

Confidential Treatment Requested by Plus Therapeutics, Inc.

Pursuant to 17 C.F.R. Section 200.83

Additional Commitment Fee is paid in Additional Commitment Shares, such Additional Commitment Shares must be included in a registration statement to be filed with and declared effective by the
SEC on or prior to the date the Additional Commitment Fee is due registering under the Securities Act the resale by Lincoln Park of such Additional Commitment Shares.

As of July 30, 2025, there were 99,264,526 shares of our common stock outstanding, of which 98,785,360 shares of our common stock were
held by non-affiliates. If all of the 33,000,000 shares offered by Lincoln Park under this prospectus were issued and outstanding, such shares would represent approximately 25% of the total number of shares of
our common stock outstanding and approximately 25.0% of the total number of outstanding shares held by non-affiliates, in each case as of July 30, 2025. We have filed the registration statement that
includes this prospectus so that we may issue to Lincoln Park up to 33,000,000 shares of our common stock from time to time from and after the date of this prospectus through sales under the Purchase Agreement. Depending on the market prices of our
common stock at the time we elect to issue and sell such shares to