Company: AGIO
Filing Date: 2025-04-25
Form Type: DEF 14A
Source: 0001193125-25-096719
Chunk: 75

Company: AGIOS PHARMACEUTICALS, INC.
Filing Date: 2025-04-25
Form: DEF 14A
Chunk 75
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 above), with the performance period as set forth below:

2024 PSU Program The PSUs that we granted to our NEOs in March 2024 vest as to the underlying shares upon our compensation & people committee’s determination of the achievement of each of the following milestones, the performance period and relative weight for each milestone as set forth below:

2025 PSU Program The PSUs that we granted to our NEOs in March 2025 vest as to the underlying shares upon our compensation & people committee’s determination of the achievement of each of the following milestones, the performance period and relative weight for each milestone as set forth below:

55

We believe that PSUs further increase the performance orientation of our executive compensation program thereby leading to the compensation & people committee’s decision to formally include PSUs as part of the annual equity award mix for our executives. The PSU milestones are intended to align with a broad range of the most significant long-term value-creating objectives for the company. 2025 Executive Compensation Decisions In February 2025, our compensation & people committee (or our board of directors, upon recommendation of the compensation & people committee, for our chief executive officer) approved 2025 base salaries, target annual performance-based cash incentive percentages and annual stock option, RSU and PSU awards for our NEOs. The table below sets forth the 2025 compensation levels for our NEOs.

|                 |     | 2025         
 Target Bonus 
 Award (%)    |    |   |     | Change in    
 Target Bonus 
 Award from   
 2024         |   |     | 2025 Base 
 Salary    
 ($)       |         |     | % Base    
 Salary    
 Increase  
 over 2024 |     |      |     | 2025 Equity  
 Incentive    
 Awards       
 (Options)(1) |         |     | 2025 Equity 
 Incentive   
 Awards      
 (RSUs)(2)   |        |     | 2025 Equity 
 Incentive   
 Awards      
 (PSUs)(3)   |        |
|:----------------|:----|:-------------|---:|:--|:----|:-------------|:--|:----|:----------|--------:|:----|:----------|----:|:-----|:----|:-------------|--------:|:----|:------------|-------:|:----|:------------|-------:|
| Brian Goff      |     |              | 70 | % |     |              | — |     |