Company: RGNX
Filing Date: 2025-03-13
Form Type: POSASR
Source: 0001193125-25-053917
Chunk: 17

Company: REGENXBIO Inc.
Filing Date: 2025-03-13
Form: POSASR
Chunk 17
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 a knowing violation of law; |

| • |     | for unlawful payments of dividends or unlawful stock repurchases or redemptions, as provided under 
 Section 174 of the Delaware General Corporation Law; or                                            |

| • |     | for any transaction from which the director derived an improper personal benefit. |

Any amendment or repeal of these provisions will require the approval of the holders of shares representing at least two-thirdsof the shares entitled to vote in the election of directors, voting as one class. Our restated certificate of incorporation and amended and restated bylaws also provide that we will indemnify our directors and officers to the fullest extent permitted by Delaware law. Our restated certificate of incorporation and amended and restated bylaws also permit us to purchase insurance on behalf of any officer, director, employee or other agent for any liability arising out of his or her actions as our officer, director, employee or agent, regardless of whether Delaware law would permit indemnification. We have entered into separate indemnification agreements with our directors and officers that require us, among other things, to indemnify them against certain liabilities that may arise by reason of their status or service as directors and to advance their expenses incurred as a result of any proceeding against them as to which they could be indemnified. We believe that the limitation of liability provision in our restated certificate of incorporation and the indemnification agreements facilitate our ability to continue to attract and retain qualified individuals to serve as directors and officers. The limitation of liability and indemnification provisions in our restated certificate of incorporation and amended and restated bylaws may discourage stockholders from bringing a lawsuit against directors for breach of their fiduciary duties. They may also reduce the likelihood of derivative litigation against directors and officers, even though an action, if successful, might benefit us and our stockholders. A stockholder’s investment may be harmed to the extent we pay the costs of settlement and damage awards against directors and officers pursuant to these indemnification provisions. 9

DESCRIPTION OF WARRANTS We may issue warrants for the purchase of shares of our common stock, shares of our preferred stock or debt securities. The following description sets forth certain general terms and provisions of the warrants that we may offer pursuant to this prospectus. The particular terms of the warrants and the extent, if any, to which the general terms and provisions may apply to the warrants so offered will be described in the applicable prospectus supplement. Warrants may be issued independently or together with other securities and may be attached to or separate from any offered securities.