Company: IOBT
Filing Date: 2025-05-23
Form Type: S-3
Source: 0001193125-25-125831
Chunk: 17

Company: IO Biotech, Inc.
Filing Date: 2025-05-23
Form: S-3
Chunk 17
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 business address of the European Investment Bank is 98-100 boulevard Konrad Adenauer, L-2950 Luxembourg. |

12

PLAN OF DISTRIBUTION The selling stockholders, including their pledgees, donees, transferees, distributees, beneficiaries or other successors in interest, may from time to time offer some or all of the shares of our common stock offered under this prospectus. We will not receive any of the proceeds from the sale of the shares of our common stock offered under this prospectus by the selling stockholders. We will bear all fees and expenses incident to our obligation to register the shares of our common stock offered under this prospectus. The selling stockholders may sell all or a portion of the shares of our common stock beneficially owned by them and offered hereby from time to time directly or through one or more underwriters, broker-dealers or agents. If the shares of our common stock are sold through underwriters or broker-dealers, the selling stockholders will be responsible for underwriting discounts or commissions or agent’s commissions. The shares of our common stock may be sold on any national securities exchange or quotation service on which the securities may be listed or quoted at the time of sale, in the over-the-countermarket or in transactions otherwise than on these exchanges or systems or in the over-the-countermarket and in one or more transactions at fixed prices, at prevailing market prices at the time of the sale, at varying prices determined at the time of sale, or at privately negotiated prices. These sales may be effected in transactions, which may involve crosses or block transactions. The selling stockholders may use any one or more of the following methods when disposing of shares of our common stock or interests therein:

| • |     | ordinary brokerage transactions and transactions in which the broker-dealer solicits purchasers; |

| • |     | block trades in which the broker-dealer will attempt to sell shares of our common stock as agent, but may 
 position and resell a portion of the block as principal to facilitate the transaction;                    |

| • |     | purchases by a broker-dealer as principal and resale by the broker-dealer for its account; |

| • |     | an over-the-counter distribution; |

| • |     | an exchange distribution in accordance with the rules of the applicable exchange; |

| • |     | privately negotiated transactions; |

| • |     | short sales effected after the effective date of the registration statement of which this prospectus forms a 
 part;                                                                                                        |

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