Company: OSRH
Filing Date: 2025-01-31
Form Type: 424B3
Source: 0001213900-25-008874
Chunk: 286

Company: OSR Holdings, Inc.
Filing Date: 2025-01-31
Form: 424B3
Chunk 286
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 a connective tissue found in joints between bones such as knees, ankle, and elbow, and provides lubrication to reduce friction in the joints. The goal of osteoarthritis treatment is to alleviate pain and enhance functionality of the joints. The growth of the osteoarthritis therapeutics market is currently and will in the near -termfuture be driven by a number of factors, including a general increase in prevalence of the disease in an ageing global population that is also living longer. These factors include wider access to better treatment options as a result of technological advancements, increased investments in R&D activities for drug development including in cell -basedresearch activities, increased funding from private & government organizations for the development of the healthcare sector and research centers generally, and a rise in the number of approvals for drugs by regulatory bodies. The global osteoarthritis therapeutics market size was valued at $6.75 billion in 2020, and is estimated to reach $15.693 billion by 2030, growing at a CAGR of 8.8% from 2021 to 2030. 8 Alongside its review of the foregoing market data, the BLAC M&A Committee reviewed OSR Holdings’ asset pipeline which includes Vaximm’s drug candidates for recurrent GBM, hepatocellular cancer, metastatic colorectal cancer, and Darnatein’s drug candidate for osteoarthritis, and believes, based on each pipeline asset’s targeted therapy and the projected growth of the corresponding market, that OSR Holdings’ asset pipeline candidates have the fair market values ascribed to them by the valuation reports described in the section entitled “The Business Combination — The BLAC M&A Committee’s Reasons for the Approval of the Business Combination — Fair Market Value”which section contains a summary of the cash flow projections and detailed assumptions underlying the models in those reports. ____________ 5 https: // www.futurewiseresearch.com /healthcare -market -research /Hepatocellular -Carcinoma -(HCC) / 11543 6 https: // www.giiresearch.com / report / mx1447722 - metastatic-colorectal - cancer-market - assessment-by .html 7Dekker, E., et al. (2019). “Colorectal cancer.” The Lancet, 394(10207), 1467 -1480 8 https: // www.alliedmarketresearch.com /osteoarthritis -treatment - market-A 12691 169