Company: HCWB
Filing Date: 2025-04-28
Form Type: DEF 14A
Source: 0000950170-25-058961
Chunk: 0

Company: HCW Biologics Inc.
Filing Date: 2025-04-28
Form: DEF 14A
Chunk 0
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the
Securities Exchange Act of 1934
(Amendment No. )

| Filed by the Registrant ☒                    |                                                                                 |
| Filed by a Party other than the Registrant ☐ |                                                                                 |
| Check the appropriate box:                   |                                                                                 |
| ☐                                            | Preliminary Proxy Statement                                                     |
| ☐                                            | Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) |
| ☒                                            | Definitive Proxy Statement                                                      |
| ☐                                            | Definitive Additional Materials                                                 |
| ☐                                            | Soliciting Material under §240.14a-12                                           |

HCW BIOLOGICS INC. (Name of Registrant as Specified In Its Charter) (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

| Payment of Filing Fee (Check the appropriate box): |                                                                                                      |
| ☒                                                  | No fee required.                                                                                     |
| ☐                                                  | Fee paid previously with preliminary materials.                                                      |
| ☐                                                  | Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11. |

<div align='center'>April 28, 2025</div>

To Our Stockholders:

You are cordially invited to attend the 2025 Annual Meeting of Stockholders, or the Annual Meeting, of HCW Biologics Inc. on Tuesday, June 17, 2025 at 10:00 a.m. Eastern Time. The Annual Meeting will be a completely virtual meeting, conducted only via live webcast atwww.virtualshareholdermeeting.com/HCWB2025. You will be able to attend and participate in the Annual Meeting online, submit questions during the meeting and vote your shares electronically. In addition, although the live webcast is available only to stockholders at the time of the meeting, following completion of the Annual Meeting, a webcast replay will be available atwww.virtualshareholdermeeting.com/HCWB2025for a period of one year after the Annual Meeting.

We are proceeding under the Securities and Exchange Commission rule that allows us to furnish proxy materials to our stockholders over the internet, although we may choose to send a full set of proxy materials to some of our