Company: XOMAP
Filing Date: 2025-10-03
Form Type: 424B5
Source: 0001193125-25-230393
Chunk: 69

Company: XOMA Royalty Corp
Filing Date: 2025-10-03
Form: 424B5
Chunk 69
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 series. Our Board can, without stockholder approval but subject to the
terms of the Certificate of Incorporation and to any

10

resolution of the stockholders approved by at least 75% of all issued shares entitled to vote in respect thereof, issue Preferred Stock with voting and other rights that could adversely affect the voting power of the holders of our Common Stock and which could have certain anti-takeover effects. Before we may issue any series of Preferred Stock, our Board will be required to adopt resolutions creating and designating such series of Preferred Stock. The following summary description of the Preferred Stock of the Company, including the Series B Depositary Shares, is qualified in its entirety by reference to the provisions of the Certificate of Incorporation, By-lawsand the certificates of designation of preferences, rights and limitations of each series of the Preferred Stock, copies of which have been filed as exhibits to the Company’s Annual Report on Form 10-K,and the applicable provisions of the DGCL. As of December 31, 2023, 5,003 shares of Series X Convertible Preferred Stock, $0.05 par value (the “ Series X Preferred Stock”), 984,000 shares of Series A Preferred Stock and 1,600,000 Series B Depositary Shares, representing 1,600 shares of Series B Preferred Stock were issued and outstanding. The 8.625% Series A Cumulative Perpetual Preferred Stock.We have designated 984,000 shares of our Preferred Stock as Series A Preferred Stock. The Series A Preferred Stock will rank, as to dividend rights and rights upon our liquidation, dissolution or winding up:

| • |     | senior to all classes or series of our Common Stock and to all other equity securities issued by us expressly 
 designated as ranking junior to the Series A Preferred Stock;                                                 |

| • |     | senior with respect to the payment of dividends and on parity with respect to the distribution of assets upon our                                                                                                            
 liquidation, dissolution or winding up with our Series X Preferred Stock and on parity with any future class or series of our equity securities expressly designated as ranking on parity with the Series A Preferred Stock; |

| • |     | junior to all equity securities issued by us with terms specifically providing that those equity securities rank                                                                                              
 senior to the Series A Preferred Stock with respect to the payment of dividends and the distribution of assets upon our liquidation, dissolution or winding up, none of which exists on the date hereof; and; |

| • |     | effectively junior to