Company: NOTV
Filing Date: 2025-08-29
Form Type: S-3
Source: 0001628280-25-041413
Chunk: 3

Company: Inotiv, Inc.
Filing Date: 2025-08-29
Form: S-3
Chunk 3
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 this prospectus that contains specific information about the offering, as well as the amounts, prices and terms of the securities. Any prospectus supplement may also add, update, or change information contained in this prospectus. You should carefully read this prospectus and the applicable prospectus supplement as well as the documents incorporated or deemed to be incorporated by reference in this prospectus and the applicable prospectus supplement before you purchase any of the securities offered hereby.

These securities may be offered and sold in the same offering or in separate offerings; to or through underwriters, dealers, and agents; or directly to purchasers. The names of any underwriters, dealers, or agents involved in the sale of our securities and their compensation will be described in the applicable prospectus supplement.

Our common shares are traded on The Nasdaq Capital Market under the symbol “NOTV.” On August 26, 2025, the last reported sale price of our common shares was $1.74 per share. The applicable prospectus supplement will contain information, where applicable, as to any other listing on The Nasdaq Capital Market or any securities market or other exchange of the securities, if any, covered by the prospectus supplement.

#### Investing in our securities involves risks. See “

#### Risk Factors

#### ” on page

#### 3
, and any applicable prospectus supplement, and under similar headings in the other documents that are incorporated by reference into this prospectus and any applicable prospectus supplement.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus. Any representation to the contrary is a criminal offense.

<div align='center'>The date of this prospectus is , 2025</div>

### TABLE OF CONTENTS
|                                                      |     | Page |
| ABOUT THIS PROSPECTUS                                |     |    1 |
| PROSPECTUS SUMMARY                                   |     |    2 |
| RISK FACTORS                                         |     |    3 |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS |     |    4 |
| USE OF PROCEEDS                                      |     |    5 |
| PLAN OF DISTRIBUTION                                 |     |    6 |
| DESCRIPTION OF COMMON SHARES                         |     |    9 |
| DESCRIPTION OF PREFERRED SHARES                      |     |   14 |
| DESCRIPTION OF DEBT SECURITIES                       |     |   15 |
| DESCRIPTION OF SHARE PURCHASE CONTRACTS              |