Company: CMA
Filing Date: 2025-08-05
Form Type: 424B5
Source: 0001193125-25-173600
Chunk: 15

Company: COMERICA INC
Filing Date: 2025-08-05
Form: 424B5
Chunk 15
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 another share of parity stock or junior 
 stock; or                                                                                                   |

| • |     | through the use of the proceeds of a substantially contemporaneous sale of other shares of parity stock or junior 
 stock.                                                                                                            |

| When dividends are not paid in full on the shares of Series B Preferred Stock and any parity stock, all dividends declared on shares of Series B Preferred Stock and any such parity stock will be declared on a                                     
 proportional basis so that the amount of dividends declared per share will bear to each other the same ratio that accrued dividends for the then-current dividend period per share on Series B Preferred Stock, and accrued dividends, including any 
 accumulations, on any parity stock, bear to each other.                                                                                                                                                                                              |

S-5

| We generally will be able to pay dividends and distributions on liquidation, dissolution or winding up only out of assets legally available for such payment (after satisfaction of all claims for indebtedness and other non-equity claims). |

| If any date on which dividends would otherwise be payable is not a business day (as defined in “Description of the Series B Preferred Stock—Dividends”), then such date will nevertheless be a dividend                             
 payment date, but dividends on the Series B Preferred Stock, when, as and if declared, will be paid on the next succeeding business day without any adjustment in the amount of the dividend per share of Series B Preferred Stock. |

| No Maturity | The Series B Preferred Stock will not have any maturity date, and we will not be required to redeem or repurchase the Series B Preferred Stock. Accordingly, shares of the Series B Preferred Stock will remain outstanding indefinitely, unless and 
 until we decide to redeem or repurchase them.                                                                                                                                                                                                        |

| Redemption | We may redeem the Series B Preferred Stock at our option: |

| • |     | in whole or in part, from time to time, on any dividend payment date on or after the First Reset Date at a                                                                        
 redemption price equal to $1,000 per share (equivalent to $25 per depositary share), plus any declared and unpaid dividends, without accumulation of any undeclared dividends; or |

| • |     | in whole but not in part, at any time within 90 days following a regulatory capital treatment event (as defined                                                                                                                        
 in “Description of the Series B Preferred Stock”), at a redemption price equal to $1,000 per share (equivalent to $25 per depositary share), plus any declared and unpaid dividends, without accumulation of any undeclared dividends