Company: NCNA
Filing Date: 2025-04-24
Form Type: F-1
Source: 0001193125-25-092131
Chunk: 28

Company: NuCana plc
Filing Date: 2025-04-24
Form: F-1
Chunk 28
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 we expect to operate in the future. Forward-looking statements and estimates speak only at the date they were made, and we undertake no obligation to update or to review any forward-looking statement or estimate because of new information, future events or other factors. Forward-looking statements and estimates involve risks and uncertainties and are not guarantees of future performance. Our future results may differ materially from those expressed in these forward-looking statements and estimates. In light of the risks and uncertainties described above, the estimates and forward-looking statements discussed in this prospectus and the documents incorporated by reference herein might not occur, and our future results and our performance may differ materially from those expressed in these forward-looking statements due to, inclusive of, but not limited to, the factors mentioned above. Because of these uncertainties, you should not make any investment decision based on these estimates and forward-looking statements. 13

Website Disclosure

We maintain a public website at https://www.nucana.com and use our website as a routine channel of distribution of company information,
including press releases, analyst presentations, and supplemental financial information, as a means of disclosing material non-public information and for complying with our disclosure obligations under
Regulation FD. Our website includes an Investors section through which we make available, free of charge, our Annual Reports on Form 20-F, Reports on Form 6-K, as well
as any amendments to those reports filed or furnished pursuant to the Exchange Act as soon as reasonably practicable after we electronically file such material with, or furnish it to, the SEC. Accordingly, investors should monitor our website in
addition to following press releases, filings with the SEC, and public conference calls and webcasts.

None of the information provided on
our website, in our press releases or public conference calls and webcasts or through social media is incorporated into, or deemed to be a part of, this prospectus or in any other report or document we file with the SEC, and any references to such
website is intended to be inactive textual references only.

14

USE OF PROCEEDS

We estimate that the net proceeds from our issuance and sale of our securities in this offering, assuming all the securities we are offering
are sold, will be approximately $11.2 million, based on an assumed combined public offering price of $0.81 per ADS and accompanying Warrants, which was the closing price of our ADSs on The Nasdaq Capital Market on April 21, 2025 after deducting
Placement Agent fees and estimated offering expenses payable by us assuming no sale