Company: HURA
Filing Date: 2025-12-10
Form Type: 424B5
Source: 0001193125-25-313799
Chunk: 36

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-12-10
Form: 424B5
Chunk 36
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 of the series may declare the entire principal of all the debt securities of that series to be due and payable immediately. If a declaration occurs, the holders of a majority of the aggregate principal amount of the outstanding debt securities of that series can, subject to certain conditions, rescind the declaration. The prospectus supplement relating to each series of debt securities which are original issue discount securities will describe the particular provisions that relate to the acceleration of maturity of a portion of the principal amount of that series when an event of default occurs and continues. 8

An event of default for a particular series of debt securities does not necessarily constitute an event of default for any other series of debt securities issued under either indenture. Each indenture requires us to file an officers’ certificate with the trustee each year that states that certain defaults do not exist under the terms of the indenture. The trustee will transmit by mail to the holders of debt securities of a series notice of any default. Other than its duties in the case of a default, a trustee is not obligated to exercise any of its rights or powers under an indenture at the request, order or direction of any holders, unless the holders offer the trustee indemnification satisfactory to the trustee. If indemnification satisfactory to the trustee is provided, then, subject to certain other rights of the trustee, the holders of a majority in principal amount of the outstanding debt securities of any series may, with respect to the debt securities of that series, direct the time, method and place of:

| • |     | conducting any proceeding for any remedy available to the trustee; or |

| • |     | exercising any trust or power conferred upon the trustee. |

The holder of a debt security of any series will have the right to begin any proceeding with respect to the applicable indenture or for any remedy only if:

| • |     | the holder has previously given the trustee written notice of a continuing event of default with respect to that 
 series;                                                                                                          |

| • |     | the holders of at least 25% in aggregate principal amount of the outstanding debt securities of that series have 
 made a written request of, and offered reasonable indemnification to, the trustee to begin the proceeding;       |

| • |     | the trustee has not started the proceeding within 60 days after receiving the request; and |

| • |     | the trustee has not received directions inconsistent with the request from the holders of a majority in aggregate 
 principal amount of the outstanding debt securities of that series during those 60 days.                          |