Company: APM
Filing Date: 2025-10-14
Form Type: 424B5
Source: 0001213900-25-098635
Chunk: 70

Company: Aptorum Group Ltd
Filing Date: 2025-10-14
Form: 424B5
Chunk 70
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 advisory agreement. Dr.
Kira Sheinerman, the co-founder of DiamiR, is currently a managing director of Wainwright and upon consummation of the Merger shall be
appointed to the Combined Company’s board of directors.

In addition, in the ordinary
course of their business activities, the Placement Agent and its affiliates may make or hold a broad array of investments and actively
trade debt and equity securities (or related derivative securities) for their own account and for the accounts of their customers. Such
investments and securities activities may involve securities and/or instruments of ours or our affiliates. The Placement Agent and its
affiliates may also make investment recommendations and/or publish or express independent research views in respect of such securities
or financial instruments and may hold, or recommend to clients that they acquire, long and/or short positions in such securities and instruments.

Listing

Our Class A Ordinary Shares
are listed on the Nasdaq Capital Market under the symbol “APM.”

<div align='center'>LEGAL MATTERS</div>

Certain legal matters governed
by the laws of the Cayman Islands with respect to the validity of the offered securities will be passed upon for us by Campbells. Certain
legal matters governed by the laws of New York will be passed upon for us by Hunter Taubman Fischer & Li, LLC, New York, New York.
Ellenoff Grossman & Schole LLP, New York, New York, is counsel to H.C. Wainwright & Co., LLC in connection with this offering.

<div align='center'>EXPERTS</div>

The consolidated financial statements of our Company appearing in our annual report on Form 20-F for the fiscal years ended December 31, 2024 and 2023 have been audited by Marcum Asia CPAs LLP, an independent registered public accounting firm, as set forth in the reports thereon included therein and incorporated herein by reference. Such consolidated financial statements are incorporated herein by reference in reliance upon such reports given on the authority of such firms as experts in accounting and auditing.

<div align='center'>S-40

INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE</div>

The SEC allows us to “incorporate
by reference” into this prospectus the information we file with the SEC. This means that we can disclose important information to
you by referring you to those documents. Any statement contained in a document incorporated by reference in this prospectus shall be deemed
to be modified or superseded for purposes