Company: PRME
Filing Date: 2025-02-28
Form Type: 10-K
Source: 0001628280-25-008884
Chunk: 231

Company: Prime Medicine, Inc.
Filing Date: 2025-02-28
Form: 10-K
Item: Item 8
Chunk 231
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 We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits of these consolidated financial statements in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audits to obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement, whether due to error or fraud. The Company is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Company's internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the consolidated financial statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the consolidated financial statements. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the consolidated financial statements. We believe that our audits provide a reasonable basis for our opinion.

/s/ PricewaterhouseCoopers LLP

Boston, Massachusetts

February 28, 2025

We have served as the Company's auditor since 2021.

F-2

PRIME MEDICINE, INC.

CONSOLIDATED BALANCE SHEETS

December 31,(in thousands, except share and per share amounts)20242023AssetsCurrent assets:Cash and cash equivalents$182,476 $41,574 Short-term investments2,998 74,639 Short-term investment — related party4,968 5,452 Prepaid expenses6,777 19,057 Other current assets14,667 2,254 Total current assets211,886 142,976 Property and equipment, net24,404 22,659 Operating lease right-of-use assets47,156 13,941 Restricted cash14,062 13,496 Other assets— 779 Total assets$297,508 $193,851 Liabilities and Stockholders’ DeficitCurrent liabilities:Accounts payable$11,351 $19,537