Company: PFSA
Filing Date: 2025-09-17
Form Type: S-1/A
Source: 0001213900-25-088333
Chunk: 148

Company: Profusa, Inc.
Filing Date: 2025-09-17
Form: S-1/A
Chunk 148
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 (1,081 | ) |     |        | (208 | ) |     |   19 | %  |
| Other income (expense)                                                   |     |                |      1 |   |     |      |      1 |   |     |        |    — |   |     |    0 |    |
| Total other expense, net                                                 |     |                | (1,345 | ) |     |      | (1,095 | ) |     |        | (250 | ) |     |   23 | %  |
| Net loss                                                                 |     |              $ | (2,348 | ) |     |    $ | (2,071 | ) |     | $      | (277 | ) |     |   13 | %  |

Revenue— Grant revenue was recognized in 2024, while no grant revenue was recognized in 2025 while the Company focused on the closing on the Merger transaction. Research and Development— Research and development expenses remained constant and decreased by $39 thousand or 9% during the three months ended June 30, 2025 due to a reduction in research studies. General and Administrative— General and administrative expenses increased by $41 thousand million, or 7%, to $610 thousand during the three months ended June 30, 2025 from $569 thousand during the three months ended June 30, 2024. The increase was driven primarily by the increase in accounting costs as a result of increased audit and accounting fees. Loss on Change in the Fair Value of the Tasly Convertible Loans— Loss on change in the fair value of the Tasly Convertible Loan was less than $0.1 million during the three months ended June 30, 2025. The loss during the three months ended June 30, 2025 was driven by the remeasurement of the Tasly Convertible Loans. Interest Expense— Interest expense increased by $0.2 million to $1.3 million during the three months ended June 30, 2025 from $1.1 million during the three months ended June 30, 2024. The increase was primarily due to interest accrued on $3.5 million in additional senior notes that have been issued.

94

Comparison of the Six months ended June 30, 2025 to the Six months ended June 30, 2024 The following table sets forth our unaudited condensed consolidated statements of operations and comprehensive loss for the interim periods