Company: NDRA
Filing Date: 2025-07-09
Form Type: S-1
Source: 0001654954-25-007870
Chunk: 0

Company: ENDRA Life Sciences Inc.
Filing Date: 2025-07-09
Form: S-1
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission on July 9, 2025</div>

Registration No. 333-

<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM S-1

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933</div>

| ENDRA Life Sciences Inc.                               |
| (Exact name of registrant as specified in its charter) |

| Delaware                                                        |     |                                                     3845 |     | 26-0579295                              |
| (State or other jurisdiction of  incorporation or organization) |     | -Primary Standard Industrial  Classification Code Number |     | -I.R.S. Employer  Identification Number |

<div align='center'>3600 Green Court, Suite 350,

Ann Arbor, MI 48105-1570

(734) 335-0468

(Address, including zip code, and telephone number, including area code, of registrant’s principal executive offices)

Alexander Tokman

Chief Executive Officer

ENDRA Life Sciences Inc.

3600 Green Court, Suite 350,

Ann Arbor, MI 48105-1570

(734) 335-0468

(Name, address, including zip code, and telephone number, including area code, of agent for service)

Copies to:</div>

| Mark R. Busch, Esq. Coleman Wombwell, Esq. K&L Gates LLP 300 South Tryon St. Suite 1000 Charlotte, NC 28202 Telephone: (704) 331-7400 | Robert Charron, Esq. Ellenoff Grossman & Schole LLP 1345 Avenue of the Americas 11th Floor New York, NY 10165 Telephone: (212) 370-1300 |

Approximate date of commencement of proposed sale to the public:As soon as practicable after this Registration Statement is declared effective.

If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933 check the following box. ☒

If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐

If this Form is a post-effective amendment filed pursuant to Rule