Company: RCUS
Filing Date: 2025-02-25
Form Type: S-8
Source: 0001724521-25-000042
Chunk: 2

Company: Arcus Biosciences, Inc.
Filing Date: 2025-02-25
Form: S-8
Chunk 2
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 year ended December 31, 2024, filed with the SEC on February 25, 2025;                                                                                                                                                                                                                                                       
 the Registrant's Current Report on Form 8-K filed with the SEC onJanuary21, 2024,February 6, 2025,February 18, 2025andFebruary 19, 2025; and                                                                                                                                                                                                                                  |
|:----|:----|:------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| (c) |     | the description of the Registrant’s common stock contained in the Registrant’s Registration Statement onForm 8-A(File No.001-38419), filed with the SEC on March 9, 2018, including any amendments or reports filed for the purpose of updating such description, includingExhibit 4.2to the Registrant’s Annual Report on Form 10-K filed with the SEC on February 21, 2021. |

All other reports and documents filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) subsequent to the filing of this Registration Statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which de-registers all securities then remaining unsold shall be deemed to be incorporated by reference into this Registration Statement and to be a part hereof from the date of filing of such documents. The Registrant is not, however, incorporating any documents or information that the Registrant is deemed to furnish and not file in accordance with SEC rules. Any statement contained in a document incorporated or deemed incorporated by reference in this Registration Statement will be deemed modified or superseded for purposes of this Registration Statement to the extent that a statement contained in any subsequently filed document that also is deemed incorporated by reference in this Registration Statement modifies or supersedes that statement.

## Item 8. Exhibits
|         |     |                                                                             |     | Incorporated by Reference |     |            |     |         |     |            |     |               |
| Exhibit 
 Number  |     | Description                                                                 |     | Form                      |     | File No.   |     | Exhibit |     | FilingDate |     | FiledHerewith |
| 4.1     |     | Amended and Restated Certificate of Incorporation of Registrant.            |     | 10-Q                      |     | 001-38419  |     |