Company: RGNX
Filing Date: 2025-03-13
Form Type: POSASR
Source: 0001193125-25-053917
Chunk: 32

Company: REGENXBIO Inc.
Filing Date: 2025-03-13
Form: POSASR
Chunk 32
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 which the general terms and provisions may apply to the units so offered will be described in the applicable prospectus supplement. Each unit will be issued so that the holder of the unit also is the holder of each security included in the unit. Thus, the unit will have the rights and obligations of a holder of each included security. Units will be issued pursuant to the terms of a unit agreement, which may provide that the securities included in the unit may not be held or transferred separately at any time or at any time before a specified date. A copy of the forms of the unit agreement and the unit certificate relating to any particular issue of units will be filed with the SEC each time we issue units, and you should read those documents for provisions that may be important to you. For more information on how you can obtain copies of the forms of the unit agreement and the related unit certificate, see “Where You Can Find More Information.” The prospectus supplement relating to any particular issuance of units will describe the terms of those units, including, to the extent applicable, the following:

| • |     | the designation and terms of the units and the securities comprising the units, including whether and under what 
 circumstances those securities may be held or transferred separately;                                            |

| • |     | any provision for the issuance, payment, settlement, transfer or exchange of the units or of the securities 
 comprising the units; and                                                                                   |

| • |     | whether the units will be issued in fully registered or global form. |

23

PLAN OF DISTRIBUTION From time to time, we may sell the securities offered by this prospectus in any one or more of the following ways:

| • |     | to or through one or more underwriters, dealers or agents; |

| • |     | in short or long transactions; |

| • |     | through put or call option transactions relating to our common stock; |

| • |     | directly to agents or other purchasers; |

| • |     | in “at the market offerings” within the meaning of Rule 415(a)(4) of the Securities Act, to or through 
 a market maker or into an existing trading market, on an exchange or otherwise;                        |

| • |     | though a combination of any such methods of sale; or |

| • |     | through any other method described in the applicable prospectus supplement. |

The securities may be distributed from time to time in one or more transactions at:

| • |     | a fixed price or prices, which may be