Company: SXTPW
Filing Date: 2025-02-06
Form Type: 424B5
Source: 0001213900-25-010772
Chunk: 33

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-02-06
Form: 424B5
Chunk 33
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,898,551                                                                                     
 shares of common stock issuable upon exercise of outstanding Series B warrants at an exercise 
 price of $1.38 per share;                                                                     |

| ● | 7,076                                                                                      
 shares of common stock issuable upon exercise of the representative warrants issued to the 
 representative in our initial public offering at an exercise price of $69.96 per share;    |

| ● | 31,300                                                                                             
 shares of common stock issuable upon exercise of the representative warrants to the representative 
 in our public offering at an exercise price of $5.082 per share;                                   |

| ● | 217,391                                                                                                                                  
 shares of common stock issuable upon exercise of the representative warrants to the representative in our public offering at an exercise 
 price of $1.725 per share;                                                                                                               |

| ● | shares                                                                                     
 of common stock issuable upon the conversion of 76,480 shares of Series A Preferred Stock; |

| ● | 1,666,670 shares of common stock issuable                                                                                         
 upon the exercise of the Private Placement Warrants issued in the January 2025 Offering at an exercise price of $0.771 per share; |

| ● | 1,503,500 shares of common stock issuable                                                                                                  
 upon the exercise of the Private Placement Warrants to issued in the concurrent private placement at an exercise price of $0.59 per share; |

| ● | 76,616 shares of common stock issuable upon the exercise of placement agent warrants issued as compensation to the placement agent (or its designee) in connection with the January 2025 Offering at an exercise price of $1.2763 per share; and |

| ● | 112,763 shares of common stock issuable upon the exercise of placement agent warrants to be issued as compensation to the placement agent (or its designee) in connection with this offering at an exercise price of $0.8938 per share. |

| (2) | Unless                                                                                          
 otherwise indicated, this prospectus supplement reflects and assumes no exercise of the options 
 and warrants described above.                                                                   |

<div align='center'>S-19

RISK FACTORS</div>

Investing in our shares of common stock involves a high degree of risk. You should carefully consider the risks listed below and other information included and incorporated by reference in this prospectus supplement and accompanying prospectus. There may also be risks of which we are currently unaware, or that we currently regard as immaterial based on the information available to