Company: XXII
Filing Date: 2025-01-31
Form Type: S-3
Source: 0001493152-25-004469
Chunk: 15

Company: 22nd Century Group, Inc.
Filing Date: 2025-01-31
Form: S-3
Chunk 15
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 Nasdaq Capital Market under the symbol “XXII.”

Transfer Agent and Registrar

The transfer agent and registrar for our common stock is Continental Stock Transfer & Trust Company, One State Street, 30 thFloor, New York, NY 10004-1561.

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<div align='center'>Selling StockholderS</div>

This prospectus relates to the resale from time to time by the selling stockholders named below of 104,124 shares of our common stock. We are registering the shares of common stock in order to permit the selling stockholders to offer the shares for resale from time to time. The shares were issued to the Selling Stockholders as follows:

| ● | The Company settled $500,000 of outstanding debt and creditor                                                                             
 obligations through the issuance of 104,124 shares of common stock on January 30, 2025, pursuant to two separate settlement agreements.   
 The shares were issued in a private placement and were exempt from registration under the Securities Act of 1933, as amended, in reliance 
 on Section 4(a)(2) thereof as a transaction not involving a public offering and/or Rule 506 of Regulation D promulgated thereunder.       |

The table below lists the selling stockholders and other information regarding the beneficial ownership (as determined under Section 13(d) of the Securities Exchange Act of 1934, as amended, and the rules and regulations thereunder) of the shares of common stock held by the selling stockholders as of January 30, 2025.

The selling stockholders may sell all, some or none of their shares in this offering. See “Plan of Distribution.” Information is as of January 30, 2025 and is based on 1,717,089 shares of common stock issued and outstanding and 8,519 shares of common stock issuable upon the exercise of pre-funded warrants.

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| Name                                |     | Number of Shares of     
 Common Stock            
 Owned Prior to Offering |        |     | Maximum Number of Shares of Common           
 Stock to be Sold Pursuant to this Prospectus |        |     | Number of Shares of Common Stock Owned After Offering |   |     | Percent of Outstanding Common Stock 
 Owned After Offering                |
| North Carolina State University (1) |     |                         | 83,299 |     |                                              | 83,299 |     |                                                       | - |     | *                                   |
| Maison Placements Canada, Inc.(2)   |     |                         |