Company: APM
Filing Date: 2025-10-06
Form Type: S-4
Source: 0001213900-25-096656
Chunk: 227

Company: Aptorum Group Ltd
Filing Date: 2025-10-06
Form: S-4
Chunk 227
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 by applicable accounting standards or applicable Law; •other than in the ordinary course of business consistent with past practice, amend, modify, consent to the termination of, or waive any material rights under, any material Aptorum Contract; •fail to make in a timely manner any filings or registrations with the SEC required under the Securities Act or the Exchange Act or the rules and regulations promulgated thereunder; •engage in the conduct of any new line of business; •enter into any Contract with any broker, finder, investment banker or other Person under which such Person is or will be entitled to any brokerage fee, finders’ fee or other commission in connection with the Transactions; or •enter into any Contract that would conflict with the requirement to continue to operate its business in the ordinary course. Governance of the Combined Company Following the Merger Headquarters Aptorum and DiamiR have agreed that the Combined Company will be headquartered at DiamiR’s current corporate office in Princeton, New Jersey. Charters and Bylaws Subject to approval of the Charter Proposal, prior to the Closing, the Aptorum Delaware Charter will be amended and restated to be in the form of the Proposed Charter and Aptorum Delaware will cause the Proposed Charter to be filed with the Secretary of State of the State of Delaware in accordance with the relevant provisions of the DGCL and other applicable law of the State of Delaware. For more information on the Proposed Charter and the Charter Proposal, see the sections of this proxy statement/prospectus titled “ The Domestication Proposal (Proposal 2),”and“ Description Of Share Capital — Aptorum Delaware.” In addition, prior to the Closing, Aptorum Delaware will amend and restate its Bylaws to be in the form attached to the Merger Agreement as Exhibit B and attached as Annex A this proxy statement/prospectus (the “ Proposed Bylaws”), to be effective as of the date of the Closing. Board of Directors Immediately following the Merger, the Combined Company Board will be composed of five (5) members, two (2) of whom have been designated by DiamiR Primary Stockholder Parties and three (3) of whom has been designated by Aptorum. 113

Effective as of the Effective Time, the Aptorum board of directors will appoint the following DiamiR designees: Kira Sheinerman, Ph.D., MBA. and Laura A. Philips, Ph. D., MBA., and the following Aptorum designee: Ian Huen, Justin Wu, and Douglas Arner to the board of directors of