Company: LEU
Filing Date: 2025-11-06
Form Type: 424B5
Source: 0001104659-25-107429
Chunk: 63

Company: CENTRUS ENERGY CORP
Filing Date: 2025-11-06
Form: 424B5
Chunk 63
---
 we may loan or pledge securities to a financial institution or other third party that in turn may sell the securities
using this prospectus and an applicable prospectus supplement. Such financial institution or other third party may transfer its economic
short position to investors in our securities or in connection with a concurrent offering of other securities.

The underwriters, dealers
and agents may engage in transactions with us, or perform services for us, in the ordinary course of business for which they receive compensation.

| 25 |

<div align='center'>Legal Matters</div>

Unless otherwise indicated
in the applicable prospectus supplement, certain legal matters in connection with the offering and the validity of the securities offered
by this prospectus, and any supplement thereto, will be passed upon by O’Melveny & Myers LLP.

<div align='center'>EXPERTS</div>

The financial statements of
Centrus Energy Corp. as of December 31, 2024 and 2023, and for each of the two years in the period ended December 31, 2024,
incorporated by reference in this prospectus by reference to Centrus Energy Corp.’s Annual Report on Form 10-K for the year ended December 31, 2024, and the effectiveness of Centrus Energy Corp.’s internal control over financial reporting have been
audited by Deloitte & Touche LLP, an independent registered public accounting firm, as stated in their reports. Such financial
statements are incorporated by reference in reliance upon the reports of such firm given their authority as experts in accounting and
auditing.

The financial statements for the year ended December 31, 2022 incorporated in this Prospectus by reference to the Annual Report on Form 10-K for the year ended December 31, 2024 have been so incorporated in reliance on the report of PricewaterhouseCoopers LLP, an independent
registered public accounting firm, given on the authority of said firm as experts in auditing and accounting.

| 26 |

<div align='center'>Up to $1,000,000,000

Centrus Energy Corp.

Class A Common Stock</div>

| Prospectus 
 Supplement |

| Barclays            | Citi       | UBS Investment Bank | Evercore ISI    |
| B. Riley Securities | Guggenheim 
 Securities | MUFG                | William         
 Blair           |
| Lake                
 Street              |            |                     | Northland       
 Capital Markets |

<div align='center'>November 6, 2025</div>