Company: HCWB
Filing Date: 2025-04-07
Form Type: S-1
Source: 0001193125-25-073723
Chunk: 87

Company: HCW Biologics Inc.
Filing Date: 2025-04-07
Form: S-1
Chunk 87
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)                                            |     |        |     17,000 |     |                |    91,378 |     |              |    108,378 |     |               | *     |
| Lisa M. Giles(7)                                            |     |        |     35,815 |     |                |    91,378 |     |              |    127,193 |     |               | *     |
| All executive officers and directors as a group (8 persons) |     |        | 18,068,601 |     |                | 1,114,650 |     |              | 19,183,251 |     |               | 42.7% |

| * | Represents beneficial ownership of less than one percent of the outstanding shares of our Common Stock. |

| (1) | Consists of (a) 11,926,537 shares held directly by Dr. Hing C. Wong and (b) 4,127,619 shares held by 
 Dr. Hing C. Wong and Ms. Bee Yau Huang.                                                              |

| (2) | Consists of 77,500 shares held directly by Dr. Peter Rhode. |

| (3) | Consists of 1,381,909 shares held directly by Rebecca Byam. |

| (4) | Consists of 267,858 shares held by Garrett Capital Partners, LLC. Mr. Garrett is deemed to beneficially 
 own the shares held by Garrett Capital Partners, LLC.                                                   |

| (5) | Consists of 44,125 shares held directly by Rick S. Greene. |

| (6) | Consists of 17,000 shares held directly by Gary M. Winer. |

| (7) | Consists of 35,815 shares held by Lisa M. Giles Living Trust. |

57

SELLING STOCKHOLDERS The securities offered under this prospectus may be offered from time to time by the selling stockholder named below or by any of their respective pledgees, donees, transferees or other successors-in-interest.As used in this prospectus, the term “selling stockholder” includes the selling stockholder identified below and any donees, pledgees, transferees or other successors-in-interestselling shares received after the date of this prospectus from the selling stockholder as a gift, pledge or other non-salerelated transfer. The selling stockholder named below acquired the shares of our Common Stock being offered under this