Company: MIRM
Filing Date: 2025-08-12
Form Type: S-3ASR
Source: 0001193125-25-178937
Chunk: 61

Company: Mirum Pharmaceuticals, Inc.
Filing Date: 2025-08-12
Form: S-3ASR
Chunk 61
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 Table.                                         |

| * | To be filed by amendment or by a report filed under the Exchange Act and incorporated herein by reference, if 
 applicable.                                                                                                   |

| ** | To be filed, if applicable, in accordance with the requirements of Section 305(b)(2) of the Trust 
 Indenture Act of 1939, as amended, and Rule 5b-3 thereunder.                                      |

Item 17. Undertakings The undersigned registrant hereby undertakes: (1) To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement:

| (i) | To include any prospectus required by Section 10(a)(3) of the Securities Act; |

| (ii) | To reflect in the prospectus any facts or events arising after the effective date of the registration statement                                                                                                                                         
 (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in    
 volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus 
 filed with the SEC pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the “Calculation of Registration Fee” table in the            
 effective registration statement (which is currently filed as Exhibit 107 to the effective registration statement); and                                                                                                                                 |

| (iii) | To include any material information with respect to the plan of distribution not previously disclosed in the 
 registration statement or any material change to such information in the registration statement;             |

provided, however, that the undertakings set forth in paragraphs (1)(i), (1)(ii) and (1)(iii) above do not apply if the registration statement is on Form S-3and the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the SEC by the registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in this registration statement or is contained in a form of prospectus filed pursuant to Rule 424(b) that is part of this registration statement. (2) That, for the purpose of