Company: SCE-PL
Filing Date: 2025-01-07
Form Type: 424B5
Source: 0001193125-25-002794
Chunk: 4

Company: SOUTHERN CALIFORNIA EDISON Co
Filing Date: 2025-01-07
Form: 424B5
Chunk 4
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 utility regulators are commensurate with inflation rates);                                          |

| • |     | governmental, statutory, regulatory or administrative changes or initiatives affecting the electricity industry,                                                                                                                                       
 including the market structure rules applicable to each market adopted by the North American Electric Reliability Corporation, CAISO, Western Electricity Coordinating Council, and similar regulatory bodies in adjoining regions, and changes in the 
 United States’ and California’s environmental priorities that lessen the importance placed on greenhouse gas reduction and other climate-related priorities;                                                                                           |

| • |     | availability and creditworthiness of counterparties and the resulting effects on liquidity in the power and fuel                       
 markets and/or the ability of counterparties to pay amounts owed in excess of collateral provided in support of their obligations; and |

| • |     | cost of fuel for generating facilities and related transportation, which could be impacted by, among other                                                                    
 things, disruption of natural gas storage facilities, to the extent not recovered, timely or at all, through regulated rate cost escalation provisions or balancing accounts. |

Additional information about risks and uncertainties that could cause results to differ from those currently expected or that otherwise could impact us, including more detail about the factors described above, is included S-3

in our Annual Report on Form 10-K for the year ended December 31, 2023, our Quarterly Reports on
Form 10-Q, our Current Reports on Form 8-K, and our other filings with the SEC filed subsequent to that date. Forward-looking statements speak only as of the
date they are made and we are not obligated to publicly update or revise forward-looking statements.

S-4

SUMMARY

The following summary is qualified in its entirety by and should be read together with the more detailed information and audited financial statements, including the related bonds, contained or incorporated by reference in this prospectus supplement and the accompanying base prospectus.

Southern California Edison Company

Southern California Edison is an investor-owned public utility primarily engaged in the business of supplying and delivering electricity to an
approximately 50,000 square mile area of southern California, excluding the City of Los Angeles and certain other cities. We own and operate transmission, distribution and generation facilities for the purpose of serving our customers’
electricity needs. In addition to power provided from our own generating resources, we procure power from a variety of sources including other utilities and merchant and other non-utility generators. Based in
Rosemead, California, Southern California Edison was incorporated in California in 1909.

Southern California Edison is a subsidiary