Company: HCWB
Filing Date: 2025-04-16
Form Type: 424B3
Source: 0001193125-25-082835
Chunk: 108

Company: HCW Biologics Inc.
Filing Date: 2025-04-16
Form: 424B3
Chunk 108
---
 States
owners” or (2) provides certain information regarding the entity’s “substantial United States owners,” which will in turn be provided to the U.S. Department of Treasury. Prospective investors should consult their tax
advisors regarding the possible implications of FATCA on their investment in our securities.

72

LEGAL MATTERS

The validity of the securities offered hereby will be passed upon by Clark Hill LLP, Chicago, Illinois and Los Angeles, California.

EXPERTS

The financial statements of HCWB as of December 31, 2024 and for the year ended December 31, 2024 incorporated by reference in this
prospectus and elsewhere in the registration statement of which it forms a part by reference to the Annual Report on Form 10-K filed on March 28, 2025 have been so incorporated by reference in reliance on
the report of Crowe LLP (“Crowe”), an independent registered public accounting firm, given on the authority of said firm as experts in auditing and accounting.

The financial statements of HCWB as of December 31, 2023 and for the year ended December 31, 2023 incorporated by reference in this
prospectus and elsewhere in the registration statement of which it forms a part have been so incorporated by reference in reliance on the report of Grant Thornton LLP (“Grant Thornton”), independent registered public accountants, upon the
authority of said firm as experts in accounting and auditing.

Change in Auditor

On September 19, 2024, HCWB dismissed its previous independent accounting firm, Grant Thornton and engaged Crowe as its independent
auditor.

WHERE YOU CAN FIND MORE INFORMATION

We are subject to the informational requirements of the Exchange Act. In accordance with the Exchange Act, we file periodic reports, proxy and
information statements and other information with the SEC. Our filings with the SEC are available to the public over the Internet at the SEC’s website at www.sec.gov. You may also find documents we filed on our website at www.hcwbiologics.com.
Information contained in or accessible through our website does not constitute a part of this prospectus and is not incorporated by reference herein.

This prospectus is part of a registration statement we filed with the SEC. This prospectus omits some information contained in the
registration statement in accordance with SEC rules and regulations. You should review the information and exhibits in the registration statement for further information about us and our consolidated subsidiaries and the securities we are offering.
Statements in this prospectus concerning any document we filed as