Company: HRTX
Filing Date: 2025-08-15
Form Type: 8-A12B
Source: 0000950170-25-109236
Chunk: 0

Company: HERON THERAPEUTICS, INC. /DE/
Filing Date: 2025-08-15
Form: 8-A12B
Chunk 0
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 Heron Therapeutics, Inc. (Exact name of registrant as specified in its charter)

| Delaware                                      |     | 94-2875566                         |
| (State or other jurisdictionof incorporation) |     | -I.R.S. EmployerIdentification No. |

| 100 Regency Forest Drive, Suite 300, Cary, NC |     |     27518 |
| (Address of principal executive offices)      |     | -Zip Code |

Securities to be registered pursuant to Section 12(b) of the Act:

| Title of each classto be so registered  |     | Name of each exchange on whicheach class is to be registered |
| Common Stock, par value $0.01 per share |     | The Nasdaq Capital Market                                    |

If this form relates to the registration of a class of securities pursuant to Section 12(b) of the Exchange Act and is effective pursuant to General Instruction A.(c) or (e), check the following box. ☒ If this form relates to the registration of a class of securities pursuant to Section 12(g) of the Exchange Act and is effective pursuant to General Instruction A.(d) or (e), check the following box. ☐ If this form relates to the registration of a class of securities concurrently with a Regulation A offering, check the following box. ☐ Securities Act registration statement or Regulation A offering statement file number to which this form relates: Not Applicable Securities to be registered pursuant to Section 12(g) of the Act: None.

Item 1. Description of Registrant’s Securities to be Registered.

On August 13, 2025, the Board of Directors (the “Board”) of Heron Therapeutics, Inc. (the “Company”) adopted a Tax Benefit Preservation Plan, dated August 14, 2025, by and between the Company and Computershare Trust Company, N.A., as rights agent (as amended from time to time, the “Plan”).

By adopting the Plan, the Board is seeking to protect the Company’s ability to carry forward its net operating losses (collectively, “NOLs”). For federal and state income tax purposes, the Company may “carry forward” NOL