Company: EDSA
Filing Date: 2025-07-25
Form Type: S-3
Source: 0001171843-25-004721
Chunk: 28

Company: Edesa Biotech, Inc.
Filing Date: 2025-07-25
Form: S-3
Chunk 28
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 held through participants will be governed by standing customer instructions and customary practices, as is now the case with the securities held for the accounts of customers in bearer form or registered in “street name,” and will be the responsibility of those participants.

If the depositary for any of these securities represented by a registered global security is at any time unwilling or unable to continue as depositary or ceases to be a clearing agency registered under the Exchange Act, and a successor depositary registered as a clearing agency under the Exchange Act is not appointed by us within 90 days, we will issue securities in definitive form in exchange for the registered global security that had been held by the depositary. Any securities issued in definitive form in exchange for a registered global security will be registered in the name or names that the depositary gives to the relevant trustee or warrant agent or other relevant agent of ours or theirs. It is expected that the depositary’s instructions will be based upon directions received by the depositary from participants with respect to ownership of beneficial interests in the registered global security that had been held by the depositary.

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<div align='center'>PLAN OF DISTRIBUTION</div>

Initial Offering and Sale of Securities

Unless otherwise set forth in a prospectus supplement accompanying this prospectus, we may sell the securities being offered hereby, from time to time, by one or more of the following methods:

| · | to or through underwriting syndicates represented by managing underwriters; |

| · | through one or more underwriters without a syndicate for them to offer and sell to the public; |

| · | through dealers or agents; and |

| · | to investors directly in negotiated sales or in competitively bid transactions. |

Offerings of securities covered by this prospectus also may be made into an existing trading market for those securities in transactions at other than a fixed price, either:

| · | on or through the facilities of the Nasdaq Capital Market or any other securities exchange or quotation   
 or trading service on which those securities may be listed, quoted, or traded at the time of sale; and/or |

| · | to or through a market maker other than on the securities exchanges or quotation or trading services set 
 forth above.                                                                                             |

Those at-the-market offerings, if any, will be conducted by underwriters acting as principal or agent of the Company, who may also be third-party sellers of securities as described above. The prospectus supplement with respect to the offered securities will set forth the terms of the offering of the offered securities