Company: VCYT
Filing Date: 2025-06-17
Form Type: S-8
Source: 0001384101-25-000081
Chunk: 3

Company: VERACYTE, INC.
Filing Date: 2025-06-17
Form: S-8
Chunk 3
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 Exhibit 5.1) |     |                           |     |            |     |            |     |             |     | X              |
| 24.1        |     | Power of Attorney (contained on signature page hereto).  |     |                           |     |            |     |            |     |             |     | X              |
| 99.1        |     | 2023 Equity Incentive Plan, as amended                   |     | DEF 14-A                  |     | 001-36156  |     | Appendix A |     | 4/29/2025   |     |                |
| 99.2        |     | Form of agreements under the 2023 Equity Incentive Plan  |     | S-8 POS                   |     | 333-270147 |     |       99.6 |     | 6/8/2023    |     |                |
| 107.1       |     | Filing Fee Table                                         |     |                           |     |            |     |            |     |             |     | X              |

### SIGNATURES
Pursuant to the requirements of the Securities Act, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized in the City of South San Francisco, State of California, on the 17th day of June 2025.

| VERACYTE, INC. |     |                                      |
| By:            |     | /s/ MARC STAPLEY                     |
|                |     | Marc Stapley                         
 Chief Executive Officer and Director |

### POWER OF

### ATTORNEY
KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Marc Stapley and Rebecca Chambers and each of them, his or her true and lawful attorneys-in-fact and agents, each with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments, including post-effective amendments, to this Registration Statement on Form S-8, and to file the same, with exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission granting unto said attorneys-in-fact and agents, and each of them, full power and authority