Company: ARWR
Filing Date: 2025-12-11
Form Type: S-3ASR
Source: 0001193125-25-314755
Chunk: 12

Company: ARROWHEAD PHARMACEUTICALS, INC.
Filing Date: 2025-12-11
Form: S-3ASR
Chunk 12
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The applicable prospectus supplement will also describe any material covenants to which a series of debt securities will be subject and the applicability of those covenants to any of our subsidiaries to be restricted thereby, which are referred to herein as “restricted subsidiaries.” The applicable prospectus supplement will also describe provisions for restricted subsidiaries to cease to be restricted by those covenants. Events of Default and Remedies Unless otherwise described in the applicable prospectus supplement, an event of default with respect to any series of debt securities will be defined in the indenture or applicable supplemental indenture or authorizing resolution as being:

| • |     | our failure to pay interest on any debt security of such series when the same becomes due and payable and the 
 continuance of any such failure for a period of 30 days;                                                      |

| • |     | our failure to pay the principal or premium of any debt security of such series when the same becomes due and 
 payable at maturity, upon acceleration, redemption or otherwise;                                              |

| • |     | our failure or the failure of any restricted subsidiary to comply with any of its agreements or covenants in, or                                                                                                                                        
 provisions of, the debt securities of such series or the indenture (as they relate thereto) and such failure continues for a period of 60 days after our receipt of notice of the default from the trustee or from the holders of at least 25% in       
 aggregate principal amount of the then outstanding debt securities of that series (except in the case of a default with respect to the provisions of the indenture regarding the consolidation, merger, sale, lease, conveyance or other disposition of 
 all or substantially all of the assets of us (or any other provision specified in the applicable supplemental indenture or authorizing resolution), which will constitute an event of default with notice but without passage of time);                 |

| • |     | default under any mortgage, indenture or instrument under which there may be issued or by which there may be                                                                                                    
 secured or evidenced any indebtedness (other than non-recourse indebtedness, as defined in the indenture) for money borrowed by us or any of our restricted subsidiaries (or the payment of which is guaranteed 
 by us or any of our restricted subsidiaries), whether such indebtedness or guarantee now exists or is created after the date we issue debt securities, if that default:                                         |

| (a) | is caused by a failure to pay at final stated maturity the principal amount of such indebtedness prior to the      
 expiration