Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 276

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 276
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31, 2023, for an aggregate of 246,000 shares are subject to vesting conditions related to research and financing
milestones. As of May 31, 2025, no shares remain available for future grants under the 2014 Stock Option Plan, which expired in September 2024,
and 600,000 shares remain available for future grant under the 2024 Stock Option Plan. The number of shares available under the 2024 Stock
Option Plan will increase by 2% per year or such lower number of shares as may be determined by the Company’s board of directors.

There was no stock option activity
in the three months ended August 31, 2025.

<div align='center'>153</div>

The following is an analysis
of the stock option activity under the Plans between May 31, 2023 and May 31, 2025.

|                          |     | Number |          |   |     | Weighted 
 Average  
 Exercise 
 Price    |      |     | Weighted  
 Average   
 Remaining 
 Life      |
|:-------------------------|:----|:-------|---------:|:--|:----|:---------|-----:|:----|:----------|
| Outstanding May 31, 2023 |     |        |  557,450 |   |     | $        | 6.04 |     |           |
| Granted                  |     |        |  153,000 |   |     |          | 0.01 |     |           |
| Exercised                |     |        |        — |   |     |          |    — |     |           |
| Expired or forfeited     |     |        | (198,500 | ) |     |          | 4.95 |     |           |
| Outstanding May 31, 2024 |     |        |  511,950 |   |     | $        | 4.66 |     |           |
| Granted                  |     |        |        — |   |     |          |    — |     |           |
| Exercised                |     |        |        — |   |     |          |    — |     |           |
| Expired or forfeited     |     |        |        — |   |     |          |    — |     |           |
| Outstanding May 31, 2025 |     |        |  511,950 |   |