Company: CMND
Filing Date: 2025-11-13
Form Type: 424B5
Source: 0001213900-25-109567
Chunk: 1

Company: Clearmind Medicine Inc.
Filing Date: 2025-11-13
Form: 424B5
Chunk 1
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 the securities involves a high degree of risk. See “Risk Factors” beginning on page S-6 of this prospectus supplement and in the documents incorporated by reference into this prospectus supplement and the accompanying prospectus for a discussion of information that should be considered in connection with an investment in the Common Shares.

Neither the Securities and Exchange Commission nor any state or other securities commission has approved or disapproved of these securities or determined if this prospectus supplement is truthful or complete. Any representation to the contrary is a criminal offense.

|                                  |     | Per    
 Common 
 Share  |      |     | Per        
 Pre-Funded 
 Warrant    |        |     | Total |         |
|:---------------------------------|:----|:-------|-----:|:----|:-----------|-------:|:----|:------|--------:|
| Offering price                   |     | $      | 0.20 |     | $          | 0.1999 |     | $     | 788,175 |
| Proceeds, before expenses, to us |     | $      | 0.20 |     | $          | 0.1999 |     | $     | 788,175 |

Delivery of the securities is expected to be made
on or about November 14, 2025 subject to customary closing conditions.

<div align='center'>The date of this prospectus supplement is November
13, 2025

TABLE OF CONTENTS</div>

Prospectus Supplement

|                                                   |     | Page |
| About this Prospectus Supplement                  |     | S-ii |
| Prospectus Supplement Summary                     |     |  S-1 |
| Risk Factors                                      |     |  S-6 |
| Forward-Looking Statements                        |     | S-10 |
| Capitalization                                    |     | S-12 |
| Dilution                                          |     | S-13 |
| Description of Securities We Are Offering         |     | S-14 |
| Use of Proceeds                                   |     | S-15 |
| Dividend Policy                                   |     | S-15 |
| Plan of Distribution                              |     | S-16 |
| Legal Matters                                     |     | S-16 |
| Experts                                           |     | S-16 |
| Incorporation of Certain Information by Reference |     | S-17 |
| Where You Can Find Additional Information         |     | S-18 |
| About this Prospectus                             |     |    1 |
| Our Business                                      |     |