Company: TVRD
Filing Date: 2025-10-07
Form Type: S-1/A
Source: 0001104659-25-097519
Chunk: 277

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-10-07
Form: S-1/A
Chunk 277
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 as the Audit Committee determines in the good faith exercise of its discretion. All of the transactions described above were entered into prior to the adoption of such policy.

162

PRINCIPAL SECURITYHOLDERS The following table and the related notes present certain information with respect to the beneficial ownership of our common stock by: (i) each person or group of affiliated persons known by us to be the beneficial owner of more than 5% of our common stock; (ii) each of our directors; (iii) each of our named executive officers; and (iv) all of our executive officers and directors as a group. Unless otherwise indicated in the footnotes to this table, we believe that each of the persons named in this table have sole voting and investment power with respect to the shares indicated as beneficially owned. The following table lists applicable percentage ownership based on 9,373,433 shares of our common stock outstanding as of June 30, 2025. Shares of our common stock that may be acquired by an individual or group within 60 days of June 30, 2025, pursuant to the exercise of options or warrants, are deemed to be outstanding for the purpose of computing the percentage ownership of such individual or group, but are not deemed to be outstanding for the purpose of computing the percentage ownership of our common stock of any other person shown in the table. Unless otherwise indicated, the address for the following stockholders is: c/o Tvardi Therapeutics, Inc., 3 Sugar Creek Ctr Blvd, Ste 525, Sugar Land, TX 77478.

| ​                                                                | ​ |            ​ | ​ |            ​ | ​ |
| ​                                                                | ​ |    Number of | ​ |   Percentage | ​ |
| ​                                                                | ​ |       Shares | ​ |    of Shares | ​ |
| ​                                                                | ​ | Beneficially | ​ | Beneficially | ​ |
| ​                                                                | ​ |        Owned | ​ |        Owned | ​ |
| Name of Beneficial Owner                                         |   |           -# |   |           -% |   |
| Greater than 5% Holders:                                         | ​ |            ​ | ​ |            ​ |   |
| Entities affiliated with Sporos(1)                               | ​ |      837,636 | ​ |         8.94 | % |
| Ronald A. DePinho(2)                                             | ​ |      780,992 | ​ |         8.33 | % |
| Entities