Company: TXG
Filing Date: 2025-02-13
Form Type: S-8
Source: 0001770787-25-000015
Chunk: 1

Company: 10x Genomics, Inc.
Filing Date: 2025-02-13
Form: S-8
Chunk 1
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 Emerging growth company   |     | ☐ |

| If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.  ☐ |

### REGISTRATION OF ADDITIONAL SECURITIES

### PURSUANT TO GENERAL INSTRUCTION E
Pursuant to General Instruction E to Form S-8, this Registration Statement is being filed with the Securities and Exchange Commission (the “Commission”) for the purpose of registering an additional (i) 1,222,918 shares of the registrant’s Class A common stock, par value $0.00001 per share ("Class A Common Stock"), to be issued pursuant to the registrant’s 2019 Employee Stock Purchase Plan (the "ESPP"), and (ii) 6,114,591 shares of the registrant’s Class A Common Stock to be issued pursuant to the registrant’s 2019 Omnibus Incentive Plan (the "Omnibus Incentive Plan"), which are the same class as those securities previously registered on effective registration statements on Form S-8 filed with the Commission on February 15, 2024 (File No. 333- 277120 ) (the "2024 Registration Statement"), February 16, 2023 (File No. 333-269837 ) (the "2023 Registration Statement"), February 18, 2022 (File No. 333-262863 ) (the “2022 Registration Statement”), March 1, 2021 (File No. 333-253667 ) (the “2021 Registration Statement) and September 12, 2019 (File No. 333-233720 ) (the “2019 Registration Statement”), and the contents of the 2019 Registration Statement, 2021 Registration Statement, 2022 Registration Statement, 2023 Registration Statement and 2024 Registration Statement, as amended, or as modified or superseded pursuant to Rule 412 under the Securities Act of 1933, as amended (the "Securities Act"), are incorporated by reference into this Registration Statement.

# PART II

### INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

## Item 3. Incorporation of Documents by Reference.
The following documents filed with the Commission by the registrant pursuant to the Securities Act and the Securities Exchange Act of 1934, as amended (the “