Company: RPTX
Filing Date: 2025-12-03
Form Type: PREM14A
Source: 0001193125-25-306948
Chunk: 284

Company: Repare Therapeutics Inc.
Filing Date: 2025-12-03
Form: PREM14A
Chunk 284
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| By:                    |     | /s/ Jon Adkins                |
|                        |     | Name: Jon Adkins              |
|                        |     | Title: President & Co-Founder |

| XENO ACQUISITION CORP. |     |                                           |
| By:                    |     | /s/ Jon Adkins                            |
|                        |     | Name: Jon Adkins                          |
|                        |     | Title: President, Secretary and Treasurer |

| REPARE THERAPEUTICS INC. |     |                                         |
| By:                      |     | /s/ Steve Forte                         |
|                          |     | Name: Steve Forte                       |
|                          |     | Title: Director, President, CEO and CFO |

| solely for the purposes of Section 9.15 hereof, 
 XOMA ROYALTY CORPORATION                        |     |                                |
| By:                                             |     | /s/ Owen Hughes                |
|                                                 |     | Name: Owen Hughes              |
|                                                 |     | Title: Chief Executive Officer |

A-53

SCHEDULE A PLAN OF ARRANGEMENT PLAN OF ARRANGEMENT UNDER CHAPTER XVI – DIVISION II OF THE BUSINESS CORPORATIONS ACT (QUÉBEC) ARTICLE 1 INTERPRETATION

| 1.1 | Definitions |

Unless indicated otherwise, where used in this Plan of Arrangement, capitalized terms used but not defined herein shall have the meanings ascribed thereto in the Arrangement Agreement and the following terms shall have the following meanings (and grammatical variations of such terms shall have corresponding meanings):

| (a) | “Affected Securities” means the Common Shares, the Incentive Securities and the Warrant. |

| (b) | “Affected Securityholders” means the Shareholders, the holders of Incentive Securities and 
 the holder of the Warrant.                                                                 |

| (c) | “AMF” means the Autorité des marchés financiers (Québec). |

| (d) | “Arrangement” means an arrangement under Chapter XVI – Division II of the QBCA in                                                                                                                                                                 
 accordance with the terms and subject to the conditions set out in this Plan of Arrangement, subject to any amendments or variations to this Plan of Arrangement made in accordance with the terms of the Arrangement Agreement or Section 5.1 of 
 this Plan of Arrangement or made at the direction of the Court in the Final Order with the prior written consent of the Company and the Purchaser, each