Company: SCLXW
Filing Date: 2025-05-07
Form Type: POS AM
Source: 0001193125-25-115054
Chunk: 5

Company: Scilex Holding Co
Filing Date: 2025-05-07
Form: POS AM
Chunk 5
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 registration of these securities were previously paid in connection with the filing of the Original Registration Statements.

The information in this preliminary prospectus is not complete and may be changed. These securities may not be sold until the registration statement filed with the U.S. Securities and Exchange Commission is effective. This preliminary prospectus is not an offer to sell these securities and it is not soliciting an offer to buy these securities in any jurisdiction where the offer or sale is not permitted.

PRELIMINARY — SUBJECT TO COMPLETION, DATED MAY 7, 2025 PRELIMINARY PROSPECTUS SCILEX HOLDING COMPANY Up to 3,593,288 Shares of Common Stock Up to 3,250,000 Shares of Common Stock offered by the Selling Securityholder This prospectus relates to the issuance by us of up to an aggregate of 3,593,288 shares of our Common Stock issuable as follows:

| (i) | 122,132 shares of Common Stock issuable upon exercise of the warrants to purchase shares of Common Stock issued in an underwritten offering consummated in March 2024, consisting of (a) 108,686 shares having an exercise price of $59.50 per share and (b) 13,446 shares having an exercise price of $74.38 per share ((a) and (b) collectively, the “February 2024 BDO Warrants”); |

| (ii) | 462,858 shares of Common Stock issuable upon exercise of the warrants to purchase shares of Common Stock issued in a registered direct offering consummated in April 2024, consisting of (a) 428,572 shares having an exercise price of $38.50 per share and (b) 34,286 shares having an exercise price of $43.75 per share ((a) and (b) collectively, the “April 2024 RDO Warrants”); |

| (iii) | 319,132 shares of Common Stock issuable upon exercise of the warrants to purchase shares of Common Stock issued pursuant to a securities purchase agreement (the “Tranche B Securities Purchase Agreement”), dated as of October 7, 2024, having a current exercise price of $36.40 per share (collectively, the “October 2024 Warrants”); |

| (iv) | 914,823 shares of Common Stock issuable upon conversion of the senior convertible notes issued pursuant to the Tranche B Securities Purchase Agreement, having a current