Company: TXG
Filing Date: 2025-04-14
Form Type: DEF 14A
Source: 0001770787-25-000018
Chunk: 2

Company: 10x Genomics, Inc.
Filing Date: 2025-04-14
Form: DEF 14A
Chunk 2
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act such other business as may properly come before the meeting or any adjournment(s) or postponement(s) thereof.                                                                                                                                                                                                   |
| YOUR VOTE                                                                                                                                                                                       
 IS IMPORTANT.                                                                                                                                                                                   
 Your vote is important. To vote your shares, please follow the instructions in the Notice of Internet Availability of Proxy Materials, which is being mailed to you on or about April 14, 2025. |     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    |     |                                                                                                                                                         |     |                                                                                                                                                                                                                           |     |                                                                                                                                                                                                                                                                                                                             |
|                                                                                                                                                                                                 |     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  These proposals are more fully described in the proxy statement ("Proxy Statement") following this Notice of Internet Availability of Proxy Materials ("Notice"). 
 Our board of directors recommends that you vote: (i) FOR the election of the nominees for Class III directors named in the Proxy Statement to serve as directors of the company; (ii) FOR the ratification of the appointment of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2025; and (iii) FOR the non-binding, advisory resolution approving the compensation of our named executive officers. You will be able to attend the meeting, submit your questions online during the meeting and vote your shares electronically at the meeting by visiting https://web.lumiconnect.com/213535898. 
                                                                                                                                                                                                                                                                                                                           Our board of directors has fixed the close of business on April 8, 2025 as the record date for the determination of the stockholders entitled to notice of, and to vote at, the 2025 Annual Meeting. Accordingly, only stockholders of record at the close of business on that date will be entitled to vote at the 2025 Annual Meeting. |     |                                                                                                                                                         |     |                                                                                                                                                                                                                           |     |                                                                                                                                                                                                                                                                                                                             |

YOUR VOTE IS IMPORTANT. Whether or not you plan to attend the 2025 Annual Meeting, we urge you to submit your vote via regular mail, online or via telephone as soon as possible to ensure your shares are represented. For additional instructions for each of these voting options, please refer to your electronic proxy materials, or the enclosed proxy card or voting instructions. We encourage

#### 10X GENOMICS, INC.12025 PROXY STATEMENT
you to vote by internet or telephone, which is convenient, conserves paper and saves the company postage and other costs. Returning the proxy does not deprive you of your right to attend the 2025 Annual Meeting and to vote your