Company: NCNA
Filing Date: 2025-03-18
Form Type: 6-K
Source: 0001193125-25-056668
Chunk: 2

Company: NuCana plc
Filing Date: 2025-03-18
Form: 6-K
Chunk 2
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 given by that resolution as if Section 561(1) of the Act did not apply to any such allotment, provided that such               
 authority shall be limited to the allotment of equity securities up to a nominal amount of £20,000,000, such authority to expire on June 30, 2026 or, if earlier, the conclusion of the annual general meeting of the Company to be held in             
 2026, but prior to its expiry the Company may make offers, and enter into agreements, which would, or might, require equity securities to be allotted after the authority expires and the Directors may allot equity securities under any such offer or 
 agreement as if the authority had not expired.                                                                                                                                                                                                          |

On or about March 18, 2025, Citibank, N.A., in its capacity as the depositary bank (the “Depositary”) for the Company’s American Depositary Shares (“ADSs”), commenced mailing notice materials and voting cards to ADS holders to enable ADS holders of record as of March 11, 2025 to instruct the Depositary to vote the ordinary shares represented by their ADSs. If the Depositary receives timely voting instructions from an ADS holder, it will endeavor to vote the ordinary shares (in person or by proxy) represented by the holder’s ADSs in accordance with the ADS holder’s voting instructions. The ability of the Depositary to carry out voting instructions may be limited by practical and legal limitations and ADS holders may not receive voting materials in time to enable them to return voting instructions to the Depositary in a timely manner. The notice materials to be mailed by the Depositary to ADS holders will contain a link to the Company’s website where ADS holders can view and download the GM notice distributed by the Company to its ordinary shareholders (which contains explanatory notes for the resolutions being voted on at the GM).

The information in this report on Form 6-Kis being furnished and the notice of the GM, including the explanatory notes providing an explanation to the resolutions being put to shareholders is being furnished in this report on Form 6-Kas Exhibit 99.1 and neither shall be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, unless expressly set forth by specific reference in such a filing. Exhibits

| Exhibit |     | Description                      |
| 99.1