Company: HURA
Filing Date: 2025-06-06
Form Type: 425
Source: 0001193125-25-137145
Chunk: 27

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-06-06
Form: 425
Chunk 27
---
 the provisions hereof.

10

(h) . If any part or provision of this Warrant is held unenforceable or
in conflict with the applicable laws or regulations of any jurisdiction, the invalid or unenforceable part or provisions shall be replaced with a provision which accomplishes, to the extent possible, the original business purpose of such part or
provision in a valid and enforceable manner, and the remainder of this Warrant shall remain binding upon the parties hereto.

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

11

IN WITNESS WHEREOF, the Company has caused this Warrant to be duly executed by its authorized officer as of the date first indicated above.

| TUHURA BIOSCIENCES, INC. |     |                                              |
| By:                      |     |                                              |
|                          |     | Name: James A. Bianco, M.D. Title: President 
 and Chief Executive Officer                  |

12

SCHEDULE 1 ASSIGNMENT FORM ( To assign the foregoing Warrant, execute this form and supply required information. Do not use this form to purchase shares.) FOR VALUE RECEIVED, the foregoing Warrant and all rights evidenced thereby are hereby assigned to:

| Name:               |     |               |
|                     |     | -Please Print |
| Address:            |     |               |
|                     |     | -Please Print |
| Phone Number:       |     |               |
| Email Address:      |     |               |
| Dated:              |     |               |
| Holder’s Signature: |     |               |
| Holder’s Address:   |     |               |

13

SCHEDULE 2 FORM OF EXERCISE NOTICE [To be executed by the Holder to purchase shares of Common Stock under the Warrant] Ladies and Gentlemen: (1) The undersigned is the Holder of Warrant No. __ (the “Warrant”) issued by TuHURA Biosciences, Inc., a Nevada corporation (the “Company”). Capitalized terms used herein and not otherwise defined herein have the respective meanings set forth in the Warrant. (2) The undersigned hereby exercises its right to purchase _____ Warrant Shares pursuant to the Warrant. (3) The Holder intends that payment of the Exercise Price shall be made as (check one):

| ☐ | Cash Exercise |

| ☐ | “Cashless Exercise” under Section 10 of the Warrant |

(4) If the Holder has elected a Cash Exercise, the Holder shall