Company: APM
Filing Date: 2025-10-06
Form Type: S-4
Source: 0001213900-25-096656
Chunk: 11

Company: Aptorum Group Ltd
Filing Date: 2025-10-06
Form: S-4
Chunk 11
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 the SEC by Aptorum, constitutes a prospectus of Aptorum under Section 5 of the Securities Act of 1933, as amended (the “Securities Act”), with respect to the shares of Aptorum Delaware common stock to be issued to DiamiR stockholders pursuant to the Merger Agreement. This document also constitutes a proxy statement of Aptorum under Section 14(a) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). It also constitutes a notice of special meeting of stockholders in lieu of annual meeting of shareholders of Aptorum. Aptorum has supplied all information contained in this proxy statement/prospectus relating to Aptorum, and DiamiR has supplied all such information relating to DiamiR. Aptorum and DiamiR have both contributed to the information related to the Merger contained in this proxy statement/prospectus. You should rely only on the information contained in this proxy statement/prospectus. Aptorum and DiamiR have not authorized anyone to provide you with information that is different from that contained in this proxy statement/prospectus. This proxy statement/prospectus is dated October6, 2025, and you should not assume that the information contained in this proxy statement/prospectus is accurate as of any date other than such date unless otherwise specifically provided herein. Further, you should not assume that the information contained in this proxy statement/prospectus is accurate as of any date other than the stated date. Neither the mailing of this proxy statement/prospectus to Aptorum shareholders nor the issuance by Aptorum Delaware of shares of its common stock pursuant to the Merger Agreement will create any implication to the contrary. This proxy statement/prospectus does not constitute an offer to sell, or a solicitation of an offer to buy, any securities, or the solicitation of a proxy, in any jurisdiction to or from any person to whom it is unlawful to make any such offer or solicitation in such jurisdiction. We are aware that in recent years, the Chinese government initiated a series of regulatory actions and statements to regulate business operations in China with little advance notice, including cracking down on illegal activities in the securities market, enhancing supervision over China -basedcompanies listed overseas using variable interest entity (“VIE”) structure, adopting new measures to extend the scope of cybersecurity reviews, and expanding the efforts in anti -monopolyenforcement. Since these regulatory actions and statements are new, it is highly uncertain how soon legislative or administrative regulation making bodies will respond and what existing or new laws