Company: SXTPW
Filing Date: 2025-09-05
Form Type: 424B5
Source: 0001213900-25-085050
Chunk: 93

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-09-05
Form: 424B5
Chunk 93
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, but
only because they agree to do so in their customer agreements or because they are legally required to do so. Investors who hold securities
in street name will be indirect holders, not holders, of those securities.

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Legal Holders

Our obligations, as well as the obligations of
any applicable trustee and of any third parties employed by us or a trustee, run only to the legal holders of the securities. We do not
have obligations to investors who hold beneficial interests in global securities, in street name or by any other indirect means. This
will be the case whether an investor chooses to be an indirect holder of a security or has no choice because we are issuing the securities
only in global form.

For example, once we make a payment or give a
notice to the holder, we have no further responsibility for the payment or notice even if that holder is required, under agreements with
depositary participants or customers or by law, to pass it along to the indirect holders but does not do so. Similarly, we may want to
obtain the approval of the holders to amend an indenture, to relieve us of the consequences of a default or of our obligation to comply
with a particular provision of the indenture or for other purposes. In such an event, we would seek approval only from the holders, and
not the indirect holders, of the securities. Whether and how the holders contact the indirect holders is up to the holders.

Special Considerations for Indirect Holders

If you hold securities through a bank, broker,
or other financial institution, either in book-entry form because the securities are represented by one or more global securities or in
street name, you should check with your own institution to find out:

| ● | the performance of third-party service providers; |

| ● | how it handles securities payments and notices; |

| ● | whether it imposes fees or charges; |

| ● | how it would handle a request for the holders’ consent, if ever required; |

| ● | whether and how you can instruct it to send you securities registered in your own name so you can be a holder, if that is permitted in the future; |

| ● | how it would exercise rights under the securities if there were a default or other event triggering the need for holders to act to protect their interests; and |

| ● | if the securities are in book-entry form, how the depositary’s rules and procedures will affect these matters. |

Global Securities

A