Company: SHPH
Filing Date: 2025-02-27
Form Type: 424B3
Source: 0001493152-25-008478
Chunk: 160

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-02-27
Form: 424B3
Chunk 160
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 following persons on behalf of the registrant and in the capacities and on the dates indicated.

| Signature           
 /s/                 
 Anatoly Dritschilo  
 Anatoly             
 Dritschilo          |     | Title                            
 Chairman                         
 of the board of directors,       
 Chief                            
 Executive Officer                |     | Date     
 February 
 26, 2025 |
|:--------------------|:----|:---------------------------------|:----|:---------|
|                     |     | -principal                       
 executive officer                |     |          |
| /s/                 
 Timothy J. Lorber   |     | Chief                            
 Financial Officer                |     |          |
| Timothy             
 J. Lorber           |     | -principal                       
 financial and accounting officer |     | February 
 26, 2025 |
| /s/                 
 Chris H. Senanayake |     | Director                         |     |          |
| Chris               
 H. Senanayake       |     |                                  |     | February 
 26, 2025 |
| /s/                 
 Steven Richards     |     | Director                         |     |          |
| Steven              
 Richards            |     |                                  |     | February 
 26, 2025 |
| /s/                 
 Joshua Schafer      |     | Director                         |     |          |
| Joshua              
 Schafer             |     |                                  |     | February 
 26, 2025 |
| /s/                 
 Milton Brown        |     | Director                         |     |          |
| Milton              
 Brown               |     |                                  |     | February 
 26, 2025 |
| /s/                 
 Bette Jacobs        |     | Director                         |     |          |
| Bette               
 Jacobs              |     |                                  |     | February 
 26, 2025 |

| 89 |

Exhibit 21

<div align='center'>List of Subsidiaries</div>

Shuttle Pharmaceuticals, Inc., a Maryland corporation

Shuttle Diagnostics, Inc., a Maryland corporation

Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in the Registration Statement on Form S-8 (No. 333-268758) of Shuttle Pharmaceuticals Holdings, Inc. (the “Company”) of our report dated February 26, 2025, with respect to the consolidated financial statements of the Company, included in this Annual Report on Form 10-K for the year ended December 31, 2024. Our report