Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 364

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 364
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 prospectus.

Information with respect to
beneficial ownership has been furnished by each director, officer or beneficial owner of 5% or more of our Ordinary Shares. Beneficial
ownership is determined in accordance with the rules of the SEC and generally requires that such person have voting or investment power
with respect to securities. In computing the number of Ordinary Shares beneficially owned by a person listed below and the percentage
ownership of such person, Ordinary Shares underlying options, warrants or convertible securities held by each such person that are exercisable
or convertible within 60 days of the date of this prospectus are deemed outstanding, but are not deemed outstanding for computing the
percentage ownership of any other person. Except as otherwise indicated in the footnotes to this table, or as required by applicable community
property laws, all persons listed have sole voting and investment power for all Ordinary Shares shown as beneficially owned by them. As
of the date of the prospectus, we have 3 shareholders of record holding beneficial ownership of 5% or more, none of which are located
in the United States.

<div align='center'>209</div>

Unless otherwise indicated,
the business address of each of the individuals is 17 Hanover Square, London, W1S 1BN, United Kingdom.

| Name and Address of Beneficial Owner                        |     | Class A         
 Ordinary Shares 
 Beneficially    
 Owned           |           |     | Class B         
 Ordinary Shares 
 Beneficially    
 Owned           |           |     | Percentage 
 of Total   
 Class A    
 and        
 Class B    
 Ordinary   
 Shares(1)  |       |   |     | Percentage 
 of Total   
 Voting     
 Power(2)   |       |   |
| Ian Huen(3)                                                 |     |                 | 1,900,244 |     |                 | 1,606,147 |     |            | 42.77 | % |     |            | 86.71 | % |
| K.K. Wong                                                   |     |                 |         * |     |                 |         - |     |            |     * |   |     |            |     * |   |
| Justin Wu                                                   |     |                 |         * |     |                 |         - |     |            |     * |   |     |            |     * |   |
| Douglas Arner                                               |     |                 |         * |     |                 |         - |     |            |     * |   |     |