Company: PSTV
Filing Date: 2025-04-18
Form Type: 424B3
Source: 0000950170-25-055884
Chunk: 1

Company: PLUS THERAPEUTICS, INC.
Filing Date: 2025-04-18
Form: 424B3
Chunk 1
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 1934 Date of Report (Date of earliest event reported) : April 18, 2025 PLUS THERAPEUTICS, INC. (Exact name of registrant as specified in its charter)

| Delaware                     
 (State or other jurisdiction 
 of incorporation)            | 001-34375(Commission File Number) | 33-0827593(IRS Employer 
 Identification No.)     |

| 2710 Reed Road, Suite 160, Houston, Texas 77051(Address of principal executive offices, with zip code) |

(737) 255-7194 (Registrant’s telephone number, including area code) N/A (Former name or former address, if changed since last report) Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instructions A.2. below): ¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) ¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) ¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) ¨ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) Securities registered pursuant to Section 12(b) of the Act:

| Title of each class            | Trading Symbol(s) | Name of each exchange on which registered |
| Common Stock, par value $0.001 | PSTV              | The Nasdaq Capital Market                 |

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ¨ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨

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Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements