Company: EDSA
Filing Date: 2025-09-09
Form Type: 424B5
Source: 0001171843-25-005799
Chunk: 33

Company: Edesa Biotech, Inc.
Filing Date: 2025-09-09
Form: 424B5
Chunk 33
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 the time of disposition and the Non-resident
Holder is not entitled to relief under an applicable income tax treaty or convention between Canada and the country of residence of the
Non-resident Holder. In addition, capital losses arising on the disposition or deemed disposition of common shares will not be recognized
under the Tax Act unless the common shares constitutes “taxable Canadian property” to the Non-resident Holder for purposes
of the Tax Act.

Generally, common shares will not constitute
taxable Canadian property to a Non-resident Holder provided the common shares are listed on a designated stock exchange, as defined in
the Tax Act (which currently includes the Nasdaq) at the time of the disposition the following two conditions are met concurrently: unless
at any time during the 60-month period immediately preceding the disposition, (a) one or any combination of (A) the Non-resident Holder,
(B) persons with whom the Non- resident Holder did not deal at arm’s length, and (C) partnerships in which the Non-resident Holder
or a person described in (B) holds a membership interest directly or indirectly through one or more partnerships, owned 25% or more of
the issued shares of any series or class of the capital stock of the Company and (b) more than 50% of the fair market value of common
shares was derived directly or indirectly from one or any combination of (i) real or immovable property situated in Canada, (ii) “Canadian
resource properties” (as defined in the Tax Act), (iii) “timber resource properties” (as defined in the Tax Act) and
(iv) options in respect of, or interests in, or for civil law rights in property described in (i) to (iii), whether or not such property
exists. Notwithstanding the foregoing, a common share may otherwise be deemed to be taxable Canadian property to a Non-resident Holder
for purposes of the Tax Act in certain circumstances.

Non-resident Holders whose common shares
may be taxable Canadian property should consult their own tax advisors regarding the tax and compliance considerations that may be relevant
to them. There may be additional considerations not described herein in respect of the acquisition, disposition, or holding of the common
shares by a Non-resident Holder. Such Non-resident Holders should consult their own tax advisors having regard to their particular circumstances.

| S-20 |

### PLAN OF DISTRIBUTION
We entered into the Sales Agreement with Wainwright,
pursuant to which such