Company: TAK
Filing Date: 2025-06-27
Form Type: 424B2
Source: 0001628280-25-033198
Chunk: 17

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-06-27
Form: 424B2
Chunk 17
---
 the TUSFI Indenture and the Notes. Whenever particular sections or defined terms of the TUSFI Indenture not otherwise defined herein are referred to, such sections or defined terms are incorporated herein by reference. The forms of the Notes, the Guarantee and the TUSFI Indenture have been filed as exhibits to the registration statement of which this prospectus supplement and the accompanying prospectus form a part. You may also request copies of those documents upon written request from the corporate trust office of the Trustee located at 240 Greenwich Street, New York, New York 10286.

The Notes (including the Guarantee) will be issued pursuant to the TUSFI Indenture to be dated on or around July 2, 2025 among the Issuer, the Guarantor, The Bank of New York Mellon, a banking corporation organized under the laws of New York, as Trustee, The Bank of New York Mellon, London Branch, as London paying agent, and The Bank of New York Mellon SA/NV, Dublin Branch, as registrar. The Bank of New York Mellon will initially act as paying agent, transfer agent and registrar for the Notes.

#### General
The Notes will be issued only in fully registered form without interest coupons in denominations of $200,000 and integral multiples of $1,000 in excess thereof. The Notes will be represented by one or more registered notes in global form without coupons and in certain circumstances may be represented by notes in definitive form.

The TUSFI Indenture (including the Guarantee) and the Notes do not contain any financial covenants or restrictions on the payment of dividends, the incurrence of indebtedness, including other senior indebtedness (other than as set forth under “Description of Senior Debt Securities and Guarantee—Negative Pledge” in the accompanying prospectus), or the issuance or repurchase of the Issuer’s securities. The TUSFI Indenture and the Notes do not contain any covenants or other provisions to afford protection to holders of the Notes in the event of a highly leveraged transaction or a change in control of the Issuer or the Guarantor.

The terms of the Notes and the Guarantee include those stated in the TUSFI Indenture and those made part of the TUSFI Indenture by reference to the Trust Indenture Act of 1939, as amended (the “Trust Indenture Act”). The Notes and the Guarantee are subject to all such terms, and holders of Notes should refer to the TUS