Company: AEMD
Filing Date: 2025-07-25
Form Type: DRS
Source: 0001683168-25-005397
Chunk: 6

Company: AETHLON MEDICAL INC
Filing Date: 2025-07-25
Form: DRS
Chunk 6
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 in our Annual Report on Form 10-K for the fiscal year ended March 31, 2025 filed with the Securities and Exchange Commission (the SEC) on June 26, 2025.

Neither the SEC nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

Delivery of the common stock,
pre-funded warrants and accompanying warrants offered in the Company Offering is expected to be made on or about [__] subject to satisfaction
of certain customary closing conditions.

<div align='center'>Maxim Group LLC

The date of this Prospectus is , 2025</div>

<div align='center'>TABLE OF CONTENTS</div>

|                                                   |     | Page |
| About this Prospectus                             |     |    1 |
| Prospectus Summary                                |     |    2 |
| Risk Factors                                      |     |   19 |
| Special Note Regarding Forward-Looking Statements |     |   23 |
| Use of Proceeds                                   |     |   25 |
| Selling Securityholders                           |     |   26 |
| Dilution                                          |     |   27 |
| Description of Capital Stock                      |     |   29 |
| Description of Securities                         |     |   31 |
| Certain Material U.S. Federal Tax Consequences    |     |   33 |
| Plan of Distribution                              |     |   37 |
| Legal Matters                                     |     |   43 |
| Experts                                           |     |   43 |
| Market and Industry Data                          |     |   43 |
| Where You Can Find More Information               |     |   44 |
| Incorporation of Certain Information by Reference |     |   44 |

| i |

<div align='center'>ABOUT THIS PROSPECTUS</div>

You should read this prospectus, including the
information incorporated by reference herein.

Neither, we, the Selling
Securityholders nor the placement agent have authorized anyone to provide you with information that is different from that contained in
this prospectus or in any free writing prospectus we may authorize to be delivered or made available to you. We take no responsibility
for, and can provide no assurance as to the reliability of, any other information that others may give you. Neither the delivery of this
prospectus nor the sale of our securities means that the information contained in this prospectus or any free writing prospectus is correct
after the