Company: AZN
Filing Date: 2025-06-26
Form Type: 11-K
Source: 0001683168-25-004771
Chunk: 8

Company: ASTRAZENECA PLC
Filing Date: 2025-06-26
Form: 11-K
Chunk 8
---
 types of investment contracts: traditional GICs and synthetic wraps. A traditional GIC is an investment contract issued
by an insurance company or bank that provides for the payment of a specified rate of interest to the Plan and for the repayment of principal
when the contract matures. A synthetic wrap unbundles the investment and insurance components of a traditional GIC. The Plan invests
in and retains ownership of a pool of fixed income securities (e.g., government securities, pooled separate accounts, private and public
mortgage-backed securities, other asset-backed securities and investment grade corporate obligations, etc.).

These securities are “wrapped”
by a synthetic investment contract issued by a bank or insurance company that insures that participant-initiated withdrawals from the
synthetic investment contract will be paid at contract value. The gain or loss on the underlying investments is recognized over time
by adjusting the interest rate credited to the Plan under the synthetic wrap.

| 9 |

<div align='center'>ASTRAZENECA SAVINGS AND SECURITY PLAN

Notes to Financial Statements

December 31, 2024 and 2023

_______________</div>

| 3. | Fully Benefit-Responsive Investment Contracts. continued: |

The following table lists the investment
contract values as of December 31, 2024 and 2023:

|             | Type of Contract | Contract Value |        2024 |     |   |        2023 |
|:------------|:-----------------|:---------------|------------:|:----|:--|------------:|
| Traditional |                  | $              | 112,221,098 |     | $ | 156,309,898 |
| Synthetic   |                  |                | 142,676,585 |     |   | 139,254,508 |
| Total       |                  | $              | 254,897,683 |     | $ | 295,564,406 |

Fully benefit-responsive
investment contracts guarantee that (1)the crediting rate provided under the contract will not fall
below zero and (2) participant-initiated withdrawals from the fund (i.e., withdrawals as a result of death, disability, retirement, termination
of employment, hardship withdrawal, loan, and transfers to a non-competing fund) will be covered at contract value.

Certain
events might limit the ability of the Plan to transact at contract value with the issuer. In certain circumstances, the amount withdrawn
from the contract would be payable at fair value rather than at contract value