Company: SCLXW
Filing Date: 2025-11-24
Form Type: 424B3
Source: 0001193125-25-293873
Chunk: 12

Company: Scilex Holding Co
Filing Date: 2025-11-24
Form: 424B3
Chunk 12
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| Title:                 |     | Chief Executive Officer and President |

[Holder Signature Page Follows]

Accepted and Agreed to:

Name of Purchaser: Armistice Capital Master Fund Ltd.

Signature of Authorized Signatory of Purchaser: /s/ Steven Boyd

Name of Authorized Signatory: Steven Boyd

Title of Authorized Signatory: CIO of Armistice Capital, LLC, the Investment Manager

Number of Existing Warrants: 904,396

Aggregate
Warrant Exercise Price at the Reduced Exercise Price being exercised contemporaneously with signing this letter agreement: $20,357,953.96

Existing Warrants Beneficial Ownership Blocker: ☒ 4.99% or ☐ 9.99%

New Warrants: 1,356,594 (150% warrant coverage)

New Warrants Beneficial Ownership Blocker: ☒ 4.99% or ☐ 9.99%

DTC Instructions: Please reach out to settlements@armisticecapital.com

[Holder signature page to SCLX Inducement Offer]

Annex A Representations, Warranties and Covenants of the Company. The Company hereby makes the following representations and warranties to the Holder:

| a) | SEC Reports. The Company has filed all reports, schedules, forms, statements and other documents                                                                                                                                                     
 required to be filed by the Company under Section 13(a) or 15(d) of the Exchange Act for the one year preceding the date hereof (or such shorter period as the Company was required by law or regulation to file such material) (the foregoing       
 materials, including the exhibits thereto and documents incorporated by reference therein “SEC Reports”). As of their respective dates, the SEC Reports complied in all material respects with the requirements of the Exchange Act                  
 and none of the SEC Reports, when filed, contained any untrue statement of a material fact or omitted to state a material fact required to be stated therein or necessary in order to make the statements therein, in the light of the circumstances 
 under which they were made, not misleading. The Company is not currently an issuer identified in Rule 144(i) under the Securities Act.                                                                                                               |

| b) | Authorization; Enforcement. The Company has the requisite corporate power and authority to enter into                                                                                                                                                     
 and to consummate the transactions contemplated by this letter agreement and otherwise to carry out its obligations hereunder. The execution and delivery of this letter agreement by the Company and the consummation by the Company of the transactions 
 contemplated hereby