Company: GHRS
Filing Date: 2025-07-29
Form Type: 20-F/A
Source: 0001140361-25-027850
Chunk: 6

Company: GH Research PLC
Filing Date: 2025-07-29
Form: 20-F/A
Chunk 6
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 able to establish and maintain for intellectual property rights covering our GH001 and GH002 product candidates; |

| • | our ability to operate our business without infringing, misappropriating, or otherwise violating the intellectual property rights and proprietary technology of third parties; |

| • | our ability to protect our intellectual property rights, including enforcing and defending intellectual property-related claims; |

| • | regulatory developments in the United States, under the laws and regulations of the EU and other jurisdictions; |

| • | continuing inflation, interest rates and foreign currency exchange rates, disruptions in global supply chains and labor markets, volatility and stress within the banking sector and the measures governments and financial services           
 companies have taken in response, and geopolitical risks and global hostilities, including any direct or indirect economic impacts resulting from Russia’s invasion of Ukraine, the ongoing military conflict between Israel and Hamas and any 
 resulting conflicts in the region, or increased tensions between China and Taiwan;                                                                                                                                                             |

| • | developments and projections relating to our competitors and our industry; |

| • | our ability to maintain an effective system of internal control over financial reporting; |

| • | the amount of time that our existing cash, cash equivalents, other financial assets and marketable securities will be sufficient to fund our operations and capital expenditures; |

| • | our estimates regarding expenses, capital requirements and needs for additional financing; |

| • | our ability to effectively manage our anticipated growth; |

| • | our ability to attract and retain qualified employees and key personnel; |

| • | whether we are classified as a passive foreign investment company for current and future periods; |

| • | our expectations regarding the time during which we will be an emerging growth company under the Jumpstart our Business Startups Act of 2012, or the JOBS Act, and as a foreign private issuer; |

| • | the future trading price of the ordinary shares and impact of securities analysts’ reports on these prices; and |

| • | other risks and uncertainties, including those listed under “Item 3. Key Information—D. Risk Factors.” |

These forward-looking statements speak only as of the date of this Annual Report and are subject to a number of risks, uncertainties and assumptions described under the sections in this Annual Report entitled “Item 3. Key Information—D. Risk Factors” and “Item 5. Operating and Financial Review and Prospects” and elsewhere in this Annual Report. Because forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified and some