Company: CLM
Filing Date: 2025-04-21
Form Type: 424B3
Source: 0001398344-25-007380
Chunk: 42

Company: Cornerstone Strategic Investment Fund, Inc.
Filing Date: 2025-04-21
Form: 424B3
Chunk 42
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 effects on U.S. and world economies and markets generally. Likewise, natural and environmental
disasters, such as, for example, earthquakes, fires, floods, hurricanes, tsunamis and weather-related phenomena generally, as well as
the spread of infectious illness or other public health issues, including widespread epidemics or pandemics such as the COVID-19 outbreak
in 2020, and systemic market dislocations can be highly disruptive to economies and markets. Those events as well as other changes in
non-U.S. and domestic economic and political conditions also could adversely affect individual issuers or related groups of issuers,
securities markets, interest rates, credit ratings, inflation, investor sentiment, and other factors affecting the value of Fund investments.

| 32 |

The COVID-19 outbreak in 2020 resulted in travel
restrictions and disruptions, closed borders, enhanced health screenings at ports of entry and elsewhere, disruption of and delays in
healthcare service preparation and delivery, quarantines, event cancellations and restrictions, service cancellations or reductions,
disruptions to business operations, supply chains and customer activity, lower consumer demand for goods and services, as well as general
concern and uncertainty that has negatively affected the economic environment. The impact of this outbreak and any other epidemic or
pandemic that may arise in the future could adversely affect the economies of many nations or the entire global economy, the financial
performance of individual issuers, borrowers and sectors and the health of capital markets and other markets generally in potentially
significant and unforeseen ways. This crisis or other public health crises may also exacerbate other pre-existing political, social and
economic risks in certain countries or globally. The foregoing could lead to a significant economic downturn or recession, increased
market volatility, a greater number of market closures, higher default rates and adverse effects on the values and liquidity of securities
or other assets. Such impacts, which may vary across asset classes, may adversely affect the performance of the Fund and a stockholder’s
investment in the Fund.

Issuer Specific Changes.Changes in the financial condition of an issuer, changes in the specific economic or political conditions that affect a particular type of security or issuer, and changes in general economic or political conditions can affect the credit quality or value of an issuer’s securities. Lower-quality debt securities tend to be more sensitive to these changes than higher-quality debt securities.

Closed-End Fund Risk.Closed-end investment companies are subject to the risks of investing in the underlying securities. The Fund, as a