Company: NCEL
Filing Date: 2025-07-18
Form Type: F-4/A
Source: 0001213900-25-065783
Chunk: 730

Company: NewcelX Ltd.
Filing Date: 2025-07-18
Form: F-4/A
Chunk 730
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 well with diabetes is an early diagnosis — the longer a person lives with undiagnosed and untreated diabetes, the worse their health outcomes are likely to be. Easy access to basic diagnostics, such as blood glucose testing, should therefore be available in primary health care settings. Patients will need periodic specialist assessment or treatment for complications. A series of cost -effectiveinterventions can improve patient outcomes, regardless of what type of diabetes they may have. These interventions include blood glucose control through a combination of diet, physical activity and, if necessary, medication; control of blood pressure and lipids to reduce cardiovascular risk and other complications; and regular screening for damage to the eyes, kidneys and feet to facilitate early treatment. ____________ 1Worldometer — Countries in the world by population (2024) — https://www.worldometers.info/world-population/population-by-country/ 2CDC — National ALS registry dashboard — https://www.cdc.gov/als/dashboard/index.html 3Carolyn A. Brown, Cathy Lally, Varant Kupelian, W. Dana Flanders; Estimated Prevalence and Incidence of Amyotrophic Lateral Sclerosis and SOD1 and C9orf72 Genetic Variants. Neuroepidemiology 16 September 2021; 55 (5): 342–353. — https://doi.org/10.1159/000516752

| Moore Financial Consulting |

Annex E-16

Diabetes Prevalence According to the International Diabetes Federation (“IDF”) data, there were approx. 537 million people from the 20 – 79 age group worldwide living with diabetes (2021 data). This represents 10.5% of the world’s population in this age group. The total number is predicted to rise to 643 million (11.3%) by 2030 and to 783 million (12.2%) by 2045. In the following table are the IDF’s estimated global number of persons with Diabetes by territory:

| Region                       |     | -000’ |     |    2021 |     |     % |   |     |    2030 |     | Growth |   |
| Africa                       |     |       |     |  23,634 |     |   4.4 | % |     |  33,446 |     |   41.5 | % |
| Europe                       |     |       |     |  61,425 |     |  11.4