Company: TEM
Filing Date: 2025-02-25
Form Type: S-1
Source: 0001193125-25-034442
Chunk: 51

Company: Tempus AI, Inc.
Filing Date: 2025-02-25
Form: S-1
Chunk 51
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, Ph.D.(9)                                             |        |              |     20,149 |     |   |     |    * |     |        |              |         — |     |   |     |     — |     |              |    * |
| David R. Epstein(10)                                                     |        |              |      5,037 |     |   |     |    * |     |        |              |         — |     |   |     |     — |     |              |    * |
| Wayne A.I. Frederick, M.D.(11)                                           |        |              |     24,527 |     |   |     |    * |     |        |              |         — |     |   |     |     — |     |              |    * |
| Scott Gottlieb, M.D.(12)                                                 |        |              |     60,777 |     |   |     |    * |     |        |              |         — |     |   |     |     — |     |              |    * |
| Theodore J. Leonsis(13)                                                  |        |              |  3,469,592 |     |   |     |  2.1 |     |        |              |         — |     |   |     |     — |     |              |  1.1 |
| Nadja West, M.D.(14)                                                     |        |              |     23,277 |     |   |     |    * |     |        |              |         — |     |   |     |     — |     |              |    * |
| All current directors and executive officers as a group (13 persons)(15) |        |              | 52,358,874 |     |   |     | 31.3 |     |        |              | 5,043,789 |     |   |     | 100.0 |     |              | 63.9 |

| * | Represents beneficial ownership of less than 1%. |

| † | Percentage of total voting power represents voting power with respect to all shares of our Class A and                   
 Class B common stock, as a single class. The holders of our Class B common stock are entitled to 30 votes per share, and |

34

| holders of our Class A common stock are entitled to one vote per share. See the section titled “Description of Securities—Class A Common Stock and Class B