Company: NOTV
Filing Date: 2025-12-05
Form Type: 10-K
Source: 0001628280-25-055483
Chunk: 218

Company: Inotiv, Inc.
Filing Date: 2025-12-05
Form: 10-K
Item: Item 1
Chunk 218
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 the RMS segment, we believe there are significant barriers to becoming a global provider of research models, including the construction of bio-secure barrier production facilities, flexible-film isolator production facilities and the population of these facilities with approximately 250 species and strains of animal models (including over 80 genetically engineered rodent models), which requires years of investment and strict operating procedures. 

For DSA, we have many competitors, including two public companies in the U.S. and three public companies in China. 

For RMS, there are seven main competitors, including one public company in the U.S., four privately-held companies in the U.S., one government-funded, not-for-profit entity in the U.S., and one privately-held company in Europe. 

Industry Support and Animal Welfare

Inotiv is committed to delivering high-level health status and genetic quality, operational performance and client service. High standards of animal welfare are vital to delivering on each of these objectives and are a principal focus of Inotiv. Inotiv is an advocate for implementation of Replacement, Reduction and Refinement (“3Rs”). Members of Inotiv's scientific and technical care staff undertake continuing professional development in the field of laboratory animal science, with special focus on animal welfare and the 3Rs, and they are encouraged to publish and present within the scientific community. 

Inotiv has formed internal oversight bodies, including the Institutional Animal Care and Use Committee (IACUC) in the U.S., the Animal Welfare and Ethical Review Body (AWERB) in the U.K., and the Animal Welfare Body (AWB) in the E.U., comprising staff from many disciplines within the DSA and RMS segments, in addition to external representation, to implement applicable regulations and provide strict oversight of animal welfare matters. All of Inotiv’s animal production facilities are accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International, a private, non-profit, international accrediting organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. Our facilities are also routinely inspected by government agencies tasked with enforcing animal welfare regulations. 

Inotiv is firmly committed to the 3Rs and to reducing the number of animals used in research by emphasizing health monitoring and genetic integrity to decrease study data variability. Whenever possible, technological advances, such as new diagnostic tests for screening pathogens in laboratory rodents, micro-sampling and in vitro assays, are used. 

Laboratory animals remain an essential component in the research and development that our clients