Company: CNTB
Filing Date: 2025-09-10
Form Type: POS AM
Source: 0001193125-25-200186
Chunk: 117

Company: Connect Biopharma Holdings Ltd
Filing Date: 2025-09-10
Form: POS AM
Chunk 117
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 filing on Form F-3and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of San Diego, California, on September 10, 2025.

| CONNECT BIOPHARMA HOLDINGS LIMITED |     |                          |
| By:                                |     | /s/ Barry D. Quart       |
|                                    |     | Barry D. Quart, Pharm.D. |
|                                    |     | Chief Executive Officer  |

POWER OF ATTORNEY Each of the undersigned officers and directors of the registrant hereby severally constitutes and appoints Barry D. Quart as his or her true and lawful attorney-in-factand agent, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, and in any and all capacities, to file and sign any and all amendments, including post-effective amendments, to this registration statement on Form F-3,and all instruments necessary or advisable in connection therewith and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-factand agent, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith and about the premises as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorney-in-factand agent, or its substitute or substitutes, may lawfully do or cause to be done by virtue hereof. This power of attorney has been signed in the respective capacities and on the respective dates indicated below.

| SIGNATURE                        
 /s/ Barry D. Quart               
 Barry D. Quart, Pharm.D.         
 /s/ Lisa Peraza                  
 Lisa Peraza, CPA                 |     | TITLE                                        
 Chief Executive Officer and Director         
 (Principal Executive Officer)                
 Senior Vice President, Finance               
 (Principal Financial and Accounting Officer) |     | DATE               
 September 10, 2025 
 September 10, 2025 |
|:---------------------------------|:----|:---------------------------------------------|:----|:-------------------|
| *                                
 Kleanthis G. Xanthopoulos, Ph.D. |     | Chairman of the Board of Directors           |     | September 10, 2025 |
| *                                
 Kan Chen, Ph.D.                  |     | Director                                     |     | September 10, 2025 |
|