Company: HCWB
Filing Date: 2025-04-07
Form Type: S-1
Source: 0001193125-25-073723
Chunk: 0

Company: HCW Biologics Inc.
Filing Date: 2025-04-07
Form: S-1
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As filed with the Securities and Exchange Commission on April 4, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 HCW BIOLOGICS INC. (Exact name of Registrant as specified in its charter)

| Delaware                                                       |     |                                                   2834 |     | 82-5024477            |
| (State or Other Jurisdiction of Incorporation or Organization) |     | Primary Standard Industrial Classification Code Number |     | -I.R.S. Employer      
 Identification Number |

2929 N Commerce Parkway Miramar, FL 33025 (954) 842-2024 Address, including zip code, and telephone number, including area code, of Registrant’s principal executive offices Hing C. Wong, Ph.D. Chief Executive Officer HCW Biologics Inc. 2929 N Commerce Parkway Miramar, FL 33025 (954) 842-2024 Name, Address Including Zip Code, and Telephone Number, Including Area Code, of Agent for Service With a copy to:

| James Groth                               
 Clark Hill PLC 130 E.                     
 Randolph St., Ste. 3900 Chicago, IL 60601 
 (312) 985-5900                            |     | Randolf Katz                                 
 Clark Hill PLC 555 S.                        
 Flower St., 24th Floor Los Angeles, CA 90071 
 (213) 891-9100                               |

Approximate Date of Commencement of Proposed Sale to the Public:From time to time after the effective date of this registration statement, as determined by market conditions. If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the following box. ☑ If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐ If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐ If this Form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box