Company: EPR-PE
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001193125-25-309969
Chunk: 33

Company: EPR PROPERTIES
Filing Date: 2025-12-05
Form: 424B5
Chunk 33
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| • |     | Risks involved in joint ventures; |

| • |     | Risks in leasing multi-tenant properties; |

| • |     | Risks associated with litigation that could negatively impact our financial condition, cash flows, results of 
 operations and the trading price of our shares;                                                               |

| • |     | A failure to comply with the Americans with Disabilities Act or other laws; |

| • |     | Risks of environmental liability; |

| • |     | Risks associated with the relatively illiquid nature of our real estate investments; |

| • |     | Risks with owning assets in foreign countries; |

| • |     | Risks associated with owning, operating or financing properties for which the tenants’, mortgagors’ 
 or our operations may be impacted by weather conditions, climate change and natural disasters;      |

| • |     | Risks associated with the development, redevelopment and expansion of properties and the acquisition of other 
 real estate related companies;                                                                                |

| • |     | Our ability to pay dividends in cash or at current rates; |

| • |     | Risks associated with the impact of inflation or market interest rates on the value of our shares; |

| • |     | Fluctuations in the market prices for our shares; |

| • |     | Certain limits on changes in control imposed under law and by our Declaration of Trust and Bylaws; |

| • |     | Policy changes obtained without the approval of our shareholders; |

| • |     | Equity issuances that could dilute the value of our shares; |

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| • |     | Future offerings of debt or equity securities, which may rank senior to our common shares; |

| • |     | Risks associated with changes in foreign exchange rates; and |

| • |     | Changes in laws and regulations, including tax laws and regulations. |

You should consider the risks described in the “Risk Factors” section of this prospectus and the “Risk Factors” section of our most recent Annual Report on Form 10-Kand, to the extent applicable, our Quarterly Reports on Form 10-Q,in evaluating any forward-looking statements included or incorporated by reference in this prospectus. Given these uncertainties, you should not place undue reliance on forward-looking statements. Except as required by law, we undertake no obligation to publicly update or revise any forward-looking statements included or incorporated by reference in this prospectus, whether as a result of new information, future events or otherwise. In light of the