Company: FITBI
Filing Date: 2025-10-09
Form Type: 425
Source: 0001193125-25-234729
Chunk: 128

Company: FIFTH THIRD BANCORP
Filing Date: 2025-10-09
Form: 425
Chunk 128
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 common stock, par value $10.00 per share;

WHEREAS, Fifth Third, Fifth Third Intermediary, Comerica and Comerica Holdings have entered into an Agreement and Plan of Merger, dated
as of October 5, 2025 (as amended, supplemented or otherwise modified in accordance with its terms, the “”), pursuant to which, subject to the terms and conditions thereof, (i) Comerica will merge with
and into Fifth Third Intermediary (the “”), with Fifth Third Intermediary surviving the merger as the surviving corporation and (ii) immediately thereafter, Comerica Holdings will merge with and into Fifth Third
Intermediary, with Fifth Third Intermediary surviving the merger as the surviving corporation (the “” and, with the Merger, the “”);

WHEREAS,contingent upon the Mergers, on the terms and subject to the conditions contained in this Agreement, the parties to
this Agreement intend to effect the merger of each of Comerica Bank and Comerica Bank & Trust, National Association with and into Fifth Third Bank, National Association, with Fifth Third Bank, National Association surviving each such merger
(each such merger, a “,” and collectively, the “”);

WHEREAS, the board of directors of Fifth Third Bank, National Association, the board
of directors of Comerica Bank, and the board of directors of Comerica Bank & Trust, National Association have deemed the Bank Mergers advisable and in the best interests of their respective banks, and have each adopted resolutions
authorizing and approving the execution and delivery of this Agreement and the transactions contemplated hereby; and

WHEREAS,
Fifth Third Intermediary, as the sole shareholder of Fifth Third Bank, National Association, Comerica, as the sole shareholder of Comerica Bank, and Comerica Holdings, as the sole shareholder of Comerica Bank & Trust, National Association,
have adopted and approved this Agreement.

NOW, THEREFORE, in consideration of the promises and of the mutual agreements herein
contained, the parties, intending to be legally bound, hereto do hereby agree as follows:

ARTICLE I

BANK MERGER

Section 1.01 . Subject to the terms and conditions of this Agreement, at the applicable Effective Time, Comerica
Bank and Comerica Bank & Trust, National Association shall each be merged with and into Fifth Third Bank, National Association in accordance with the provisions of, and with the effects provided