Company: NCNA
Filing Date: 2025-06-18
Form Type: F-3/A
Source: 0001193125-25-142565
Chunk: 67

Company: NuCana plc
Filing Date: 2025-06-18
Form: F-3/A
Chunk 67
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     | SEC File/   
 Reg. Number |
| 25.2**  |     | The Statement of Eligibility on Form T-1 under the Trust Indenture Act of 1939, as amended, of the Trustee under the Subordinated Indenture will be incorporated herein by reference from a 
 subsequent filing in accordance with Section 305(b)(2) of the Trust Indenture Act of 1939.                                                                                                  |     |          |   |     |                     |     |        |     |             |
| 107     |     | Filing Fee Table.                                                                                                                                                                           |     |          | X |     |                     |     |        |     |             |

| * | To be subsequently filed, if applicable, by an amendment to this registration statement or by a Report on Form 6-K |

| ** | To be filed pursuant to Section 305(b)(2) of the Trust Indenture Act of 1939 |

Item 10. Undertakings. (a) The undersigned registrant hereby undertakes: (1) To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement: (i) To include any prospectus required by Section 10(a)(3) of the Securities Act of 1933, as amended, or the Securities Act; (ii) To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in Exhibit 107 of the effective registration statement; and (iii) To include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration statement; provided, however, that paragraphs (a)(1)(i), (a)(1)(ii), and (a)(1)(iii) above do not apply if the information required to be included in