Company: CYTK
Filing Date: 2025-08-07
Form Type: S-8
Source: 0001193125-25-175412
Chunk: 2

Company: CYTOKINETICS INC
Filing Date: 2025-08-07
Form: S-8
Chunk 2
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 of Incorporation. |
| 4.4(4)  |     | Certificate of Amendment of Amended and Restated Certificate of Incorporation. |
| 4.5(5)  |     | Certificate of Amendment of Amended and Restated Certificate of Incorporation. |
| 4.6(6)  |     | Certificate of Amendment of Amended and Restated Certificate of Incorporation. |
| 4.7*    |     | Certificate of Amendment of Amended and Restated Certificate of Incorporation  |
| 4.8(7)  |     | Specimen Common Stock Certificate.                                             |
| 5.1*    |     | Opinion of Cooley LLP.                                                         |
| 23.1*   |     | Consent of Independent Registered Public Accounting Firm.                      |
| 23.2*   |     | Consent of Cooley LLP (included in Exhibit 5.1).                               |
| 24.1*   |     | Power of Attorney (included on the signature page of this Form S-8).           |
| 99.1(8) |     | Amended and Restated 2004 Equity Incentive Plan.                               |
| 107*    |     | Filing Fee Table.                                                              |

| * | Filed herewith |

| (1) | Incorporated by reference to Exhibit 3.1 to the Company’s registration statement on Form S-3, registration number 333-174869, filed with the Securities and Exchange Commission on June 13, 2011. |

| (2) | Incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K, filed with the Securities and Exchange Commission on November 17, 2023. |

| (3) | Incorporated by reference to Exhibit 3.2 to the Company’s Quarterly Report on Form 10-Q, filed with the 
 Securities and Exchange Commission on August 4, 2011.                                                   |

| (4) | Incorporated by reference to Exhibit 5.1 to the Company’s Current Report on Form 8-K, filed with the Securities and Exchange Commission on June 25, 2013. |

| (5) | Incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K, filed with the Securities and Exchange Commission on May 20, 2016. |

| (6) | Incorporated by reference to Exhibit 3.5 to