Company: PFSA
Filing Date: 2025-09-17
Form Type: S-1/A
Source: 0001213900-25-088333
Chunk: 149

Company: Profusa, Inc.
Filing Date: 2025-09-17
Form: S-1/A
Chunk 149
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 ) |     |      | (2,161 | ) |     |        | (358 | ) |     |   17 | %  |
| Other income                                                             |     |                |      — |   |     |      |      6 |   |     |        |   (6 | ) |     | (100 | )% |
| Total other expense, net                                                 |     |                | (2,637 | ) |     |      | (2,166 | ) |     |        | (471 | ) |     |   22 | %  |
| Net loss                                                                 |     |              $ | (5,064 | ) |     |    $ | (4,481 | ) |     | $      | (583 | ) |     |   13 | %  |

Research and Development— Research and development expenses decreased by $0.1 million, or 12%, to $0.8 million during the six months ended June 30, 2025 from $0.9 million during the six months ended June 30, 2024. The decrease was driven primarily by the decrease in CRO and personnel costs of $0.1 million as a result of the completion of several clinical studies and a reduction of personnel while the Company focused on closing the business combination. General and Administrative— General and administrative expenses increased by $0.2 million, or 14%, to $1.6 million during the six months ended June 30, 2025 from $1.4 million during the six months ended June 30, 2024. The increase was driven primarily by the increase in accounting costs of $0.2 million as a result of increased audit and accounting fees. Loss on Change in the Fair Value of the Tasly Convertible Loans— Loss on change in the fair value of the Tasly Convertible Loan was $0.1 million during the six months ended June 30, 2025. The loss during the six months ended June 30, 2025 was driven by the remeasurement of the Tasly Convertible Loans. Interest Expense— Interest expense increased by $0.4 million, or 17%, to $2.5 million during the six months ended June 30, 2025 from $2.1 million during the six months ended June 30, 2024. The increase was primarily due to the $3.5 million in additional senior notes that have been issued. Other Income— Other income