Company: BDRX
Filing Date: 2025-11-17
Form Type: POS AM
Source: 0001214659-25-016809
Chunk: 93

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-11-17
Form: POS AM
Chunk 93
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 to
the Deposit Agreement. Such register (and/or any portion thereof) may be closed at any time or from time to time, when deemed expedient
by the depositary.

The depositary will maintain facilities
for the delivery and receipt of ADRs.

Appointment

In the Deposit Agreement, each registered
holder of ADRs and each beneficial owner, upon acceptance of any Depositary Shares or ADRs (or any interest in any of them) issued in
accordance with the terms and conditions of the Deposit Agreement will be deemed for all purposes to:

| · | be a party to and bound by the terms of the Deposit Agreement and the applicable ADR or ADRs, |

| · | appoint the depositary its attorney-in-fact, with full power to delegate, to act on its behalf and to                                      
 take any and all actions contemplated in the Deposit Agreement and the applicable ADR or ADRs, to adopt any and all procedures necessary   
 to comply with applicable laws and to take such action as the depositary in its sole discretion may deem necessary or appropriate to carry 
 out the purposes of the Deposit Agreement and the applicable ADR and ADRs, the taking of such actions to be the conclusive determinant     
 of the necessity and appropriateness thereof; and                                                                                          |

| · | acknowledge                                                                                       
 and agree that (i) nothing in the Deposit Agreement or any ADR shall give rise to a partnership   
 or joint venture among the parties thereto, nor establish a fiduciary or similar relationship     
 among such parties, (ii) the depositary, its divisions, branches and affiliates, and their        
 respective agents, may from time to time be in the possession of non-public information about     
 us, ADR holders, beneficial owners and/or their respective affiliates, (iii) the depositary       
 and its divisions, branches and affiliates may at any time have multiple banking relationships    
 with us, ADR holders, beneficial owners and/or the affiliates of any of them, (iv) the depositary 
 and its divisions, branches and affiliates may, from time to time, be engaged in transactions     
 in which parties adverse to us, ADR holders, or beneficial owners may have interests, (v)         
 nothing contained in the Deposit Agreement or any ADR(s) shall (A) preclude the depositary        
 or any of its divisions, branches or affiliates from engaging in any such transactions or         
 establishing or maintaining any such relationships, or (B) obligate the depositary or