Company: BCDRF
Filing Date: 2025-10-31
Form Type: 424B5
Source: 0001193125-25-260533
Chunk: 59

Company: Banco Santander, S.A.
Filing Date: 2025-10-31
Form: 424B5
Chunk 59
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 Trustee and the holders of the Notes (by their acceptance of the Notes) irrevocably and unconditionally waive any objection to the laying of venue of any such suit, action or other proceeding in any such courts. Agreement and Acknowledgement with Respect to the Exercise of the Bail-inPower Notwithstanding any other term of the Notes or any other agreements, arrangements, or understandings between Banco Santander and any holder of the Notes, by its acquisition of the Notes, each holder (which, for the purposes of this clause, includes each holder of a beneficial interest in the Notes) acknowledges, accepts, consents to and agrees:

| (i) | to be bound by the effect of the exercise of the Bail-in Power by the                                             
 Relevant Resolution Authority, which may include and result in any of the following, or some combination thereof: |

| • |     | the reduction of all, or a portion, of the Amounts Due on a permanent basis; |

| • |     | the conversion of all, or a portion, of the Amounts Due into Common Equity Tier 1 Instruments, other securities                                                                                                                                          
 or other obligations of Banco Santander or another person (and the issue to the holder of such Common Equity Tier 1 Instruments, securities or obligations), including by means of an amendment, modification or variation of the terms of the Notes, in 
 which case the holder agrees to accept in lieu of its rights under the Notes, any such Common Equity Tier 1 Instruments, other securities or other obligations of Banco Santander or another person;                                                     |

| • |     | the cancellation of the Notes or Amounts Due; |

| • |     | the amendment or alteration of the maturity of the Notes or amendment of the interest payable on the Notes, or 
 the date on which the interest becomes payable, including by suspending payment for a temporary period; and    |

| (ii) | that the terms of the Notes are subject to, and may be varied, if necessary, to give effect to, the exercise of 
 the Bail-in Power by the Relevant Resolution Authority.                                                         |

Each holder of the Notes also acknowledges and agrees that the foregoing description of the Bail-inPower and its exercise is exhaustive on the matters described herein to the exclusion of any other agreements, arrangements or understandings relating to the application of any Bail-inPower to the Notes. See “ Description of Debt Securities—Agreement and Acknowledgement with Respect to the Exercise of the Bail-inPower” in the accompanying prospectus. S-