Company: SION
Filing Date: 2025-08-11
Form Type: 10-Q
Source: 0002036042-25-000047
Chunk: 545

Company: Sionna Therapeutics, Inc.
Filing Date: 2025-08-11
Form: 10-Q
Item: Part I, Item 2
Chunk 545
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 to identify, develop, acquire or license additional product candidates;

•the degree and rate of physician and market adoption of any of our current and future product candidates, if successfully developed and approved;

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•manufacturing, supply or distribution delays or shortages, including our inability to obtain adequate supply of drug product, drug substance, raw materials or any commercially available product to be used in our clinical trials, at acceptable prices, or at all;

•developments or disputes concerning patent applications, issued patents or other proprietary rights;

•unanticipated serious safety concerns related to the use of our product candidates or any other product candidate;

•our cash position, and any changes in financial estimates by us or by any equity research analysts who cover our stock;

•changes in our capital structure, such as future issuances of securities and the incurrence of additional debt;

•conditions or trends in our industry;

•investors’ general perception of our company and our business;

•our ability to effectively manage our growth;

•overall performance of the equity markets;

•changes in the market valuations and stock market price and volume fluctuations of comparable companies and, in particular, those that operate in the biopharmaceutical industry;

•publication of research reports about us or our industry or positive or negative recommendations or withdrawal of research coverage by securities analysts;

•announcements by us or our competitors of significant acquisitions, strategic collaborations, joint ventures, capital commitments or divestitures;

•third-party publications and discussions about our business on social media, forums and other websites;

•recruitment or departure of key personnel;

•trading volume of our common stock;

•sales of common stock by us or our stockholders in the future;

•disputes or other developments relating to proprietary rights, including patents, litigation matters and our ability to obtain patent protection for our product candidates;

•significant lawsuits, including patent or stockholder litigation;

•changes in the structure of healthcare payment systems;

•changes in accounting standards, policies, guidelines, interpretations or principles;

•regulatory or legal developments in the U.S. and foreign countries;

•market conditions in the pharmaceutical and biotechnology sectors;

•general economic, geopolitical and stock market conditions; and

•other events or factors, many of which are beyond our control.

These and other market and industry factors may negatively affect the market price of our common stock, regardless of our actual operating performance. The realization of any of the risks described in this section, or any of a broad range of other risks, could have a material adverse impact on the