Company: QTIWW
Filing Date: 2025-01-16
Form Type: S-1
Source: 0001628280-25-001723
Chunk: 212

Company: QT IMAGING HOLDINGS, INC.
Filing Date: 2025-01-16
Form: S-1
Chunk 212
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 the knee (right). Note the higher contrast in the QTscan compared to the MRI. This exercise was conducted as part of our FDA application process and has not been published.

<div align='center'>QTScan (left) and MRI imaging (right) of a human knee

Image 14</div>

The following, Image 15 shows QTScan of the same knee from different views. Note the high contrast and detail in the QTScan image.

<div align='center'>Image 15

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Image 16 below shows QTScan of a human knee (left) compared with MRI views of the same knee (right). Note the higher contrast and detail in the QT image.

<div align='center'>QTScan (left) and MRI imaging (right) of a human knee

Image 16</div>

Image 17 below is another set of QTScan views of the same knee. Note the meniscus and cartilage detail in the QTscan images, which cannot be seen on an MRI.

<div align='center'>QTscan of a human knee

Image 17

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The Company has conducted partial-angle reconstruction studies comparing the image quality of 325-degree rotation (open angle) to 360-degree (full rotation) reconstructions (Image 18). The image quality is maintained in the partial-angle reconstruction.

<div align='center'>360-degree rotation view (left) vs partial angle reconstruction (right) of the human knee

Image 18</div>

Advantages of proposed QT Orthopedic Scanner

Compared to existing orthopedic imaging systems such as MRI and CT, the proposed QT Orthopedic Scanner will offer the following advantages:

• The QT Orthopedic Scanner may be faster at image acquisition, resulting in quicker diagnosis and treatment.

• In-office and same day orthopedic imaging

• The QT Orthopedic Scanner would not require build-out of a dedicated facility with magnetic field shielding and liquid helium supply (where needed).

• The QT Orthopedic Scanner may be less expensive to deploy than an MRI or CT device and may be less costly to maintain because the technology is simpler in design, has less components, does not utilize ionizing radiation, helium, and we anticipate will be less expensive to manufacture and maintain.

<div align='center'>140</div>

#### Proposed QT Infant Scanner—Whole Body Imaging
The Need: Currently there are very limited techniques for imaging infants. The QT Infant Scanner is in the development phase.

Background :

Medical imaging is an extremely valuable tool in