Company: SNY
Filing Date: 2025-10-27
Form Type: 424B5
Source: 0001193125-25-250786
Chunk: 30

Company: Sanofi
Filing Date: 2025-10-27
Form: 424B5
Chunk 30
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secured and unsubordinated debt.

The notes will be governed by and construed in accordance with the laws of the State of New York.

As used herein, “business day” means (i) in respect of any payment due on the Notes, each Monday, Tuesday, Wednesday,
Thursday and Friday which is not a day on which banking or trust institutions in New York or London are authorized generally or obligated by law, regulation or executive order to close; and (ii) in respect of any other matter, including any
other notice period, set forth herein or in the attached prospectus or in the Indenture, each Monday, Tuesday, Wednesday, Thursday and Friday which is not a day on which banking or trust institutions in New York or Paris are authorized generally or
obligated by law, regulation or executive order to close.

Principal, Interest and Maturity

For the purposes of this section, the notes offered pursuant to this prospectus supplement are (i) the $ floating rate
notes due 20 (the “20 floating rate notes”), (ii) the $ floating rate notes due 20 (the “20 floating rate notes” and,
together with the 20 floating rate notes, the “Floating Rate Notes”), (iii) the $ % Notes due 20 (the “20 fixed rate notes”), (iv) the
$ % Notes due 20 (the “20 fixed rate notes”), and (v) the $ % Notes due 20 (the “20 fixed rate
notes” and, together with the 20 fixed rate notes and the 20 fixed rate notes, the “Fixed Rate Notes”). In this section, we refer to the Floating Rate Notes and the Fixed Rate Notes
collectively as the “Notes.”

Fixed Rate Notes

The 20 fixed rate notes, 20 fixed rate notes and the 20 fixed rate notes will
mature at par on , 20 , , 20 and , 20 , respectively.

The 20 fixed rate notes will bear interest from , 2025, at a fixed rate of % per
annum. The 20 fixed rate notes will bear interest from , 2025, at a fixed rate of % per annum. The

S-24

20 fixed rate notes will bear interest from , 2025, at a fixed rate of % per annum. Interest on the Notes will be payable
on and of each year (each, an “Interest Payment Date”), commencing on , 2026, to the holders in whose name the