Company: HURA
Filing Date: 2025-05-23
Form Type: 424B3
Source: 0001193125-25-125499
Chunk: 356

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-05-23
Form: 424B3
Chunk 356
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     | historical information concerning TuHURA’s and Kineta’s respective businesses, financial condition, 
 results of operations,                                                                              |

| • |     | trading prices, positions in the industry, managements, competitive positions and prospects on stand-alone and 
 forecasted combined bases; and                                                                                 |

| • |     | the current and prospective business environment in which TuHURA and Kineta operate, including international,                                         
 national and local economic conditions and the competitive and regulatory environment, and the likely effect of these factors on TuHURA post-Mergers. |

The TuHURA Board of Directors weighed these advantages and opportunities against a number of potentially negative factors in its deliberations concerning the Merger Agreement and the Mergers, including:

| • |     | the risk that, because the TuHURA Share Value is fixed and will not fluctuate for changes in the market price of                                                                                                                                     
 Kineta Common Stock or TuHURA Common Stock, the then-current trading price of the shares of TuHURA Common Stock to be issued to holders of shares of Kineta Common Stock upon the consummation of the Mergers could be significantly higher than the 
 TuHURA Share Value ;                                                                                                                                                                                                                                 |

| • |     | the risk that Kineta’s financial performance may not meet TuHURA’s expectations; |

| • |     | the risk that the Mergers may not be completed or may be delayed despite the parties’ efforts, including the                                                                       
 possibility that conditions to the parties’ obligations to complete the Mergers may not be satisfied, and the potential resulting disruptions to TuHURA’s and Kineta’s businesses; |

| • |     | the potential challenges and difficulties in integrating the operations of TuHURA and Kineta and the risk that                                                                                           
 anticipated cost savings and operational efficiencies between the two companies, or other anticipated cost benefits of the Mergers, might not be realized or might take longer to realize than expected; |

| • |     | the possible diversion of management attention for an extended period of time during the pendency of the Mergers 
 and, following Closing, the integration of the two companies;                                                    |

| • |     | the effect that the length of time from announcement of the Mergers until consummation of the Mergers could have                                                                
 on the market price of TuHURA Common Stock and the relationship with TuHURA’s employees, stockholders, customers, suppliers, regulators and others who do business with TuHURA; |

| •