Company: GHRS
Filing Date: 2025-02-27
Form Type: F-3
Source: 0001140361-25-006178
Chunk: 45

Company: GH Research PLC
Filing Date: 2025-02-27
Form: F-3
Chunk 45
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 liability under the Securities Act, each filing of the registrant’s annual report pursuant to Section 13(a) or Section 15(d) of the

II-2

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Exchange Act (and, where applicable, each filing of an employee benefit plan’s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the registrant pursuant to the foregoing provisions, or otherwise, the registrant has been advised that, in the opinion of the SEC, such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer, or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the registrant will, unless, in the opinion of its counsel, the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question of whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.

The undersigned registrant hereby undertakes to file an application for the purpose of determining the eligibility of the trustee to act under Section 310 of the Trust Indenture Act (“Act”) in accordance with the rules and regulations prescribed by the Commission under section 305(b)(2) of the Act.

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TABLE OF CONTENTS

EXHIBIT INDEX

|             |     |                                                                                  |     | Incorporation by Reference |     |            |     |             |     |               |
| Exhibit No. |     | Description                                                                      |     | Form                       |     | File No.   |     | Exhibit No. |     | Filing Date   |
| 1.1*        |     | Form of Underwriting Agreement                                                   |     |                            |     |            |     |             |     |               |
| 4.1         |     | Constitution of GH Research