Company: ORBS
Filing Date: 2025-10-27
Form Type: 424B5
Source: 0001493152-25-019480
Chunk: 1

Company: Eightco Holdings Inc.
Filing Date: 2025-10-27
Form: 424B5
Chunk 1
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Agents” and include Cantor and R.F. Lafferty, each reference to the term “Sales Agreement” in the Prior Prospectus is hereby amended to refer to the A&R Sales Agreement effective as of the date of this Prospectus Supplement, and the reference to “Lucosky Brookman LLP, Woodbridge, NJ” as counsel to R.F. Lafferty in the Prior Prospectus is hereby amended to “DLA Piper LLP (US), New York, New York” as counsel to the Agents.

Our Common Stock is listed on the Nasdaq Capital Market under the symbol “OBRS.” On October 24, 2025, the last reported sale price of our Common Stock on the Nasdaq Capital Market was $6.42 per share.

Investing in our Common Stock involves significant risks. See “Risk Factors” beginning on page S-12 of Prior Prospectus and the risk factors that are incorporated by reference into the Prior Prospectus and the accompanying Base Prospectus from our filings made with the Securities and Exchange Commission (the “ SEC”) pursuant to the Exchange Act for a discussion of the factors you should carefully consider before deciding to invest in our Common Stock.

Neither the SEC nor any state securities commission has approved or disapproved of our Common Stock or determined if this prospectus is accurate, truthful or complete. Any representation to the contrary is a criminal offense.

| Cantor Fitzgerald & Co. | R.F. Lafferty & 
 Co., Inc.       |

<div align='center'>The date of this prospectus supplement is October 27, 2025.</div>