Company: NCNA
Filing Date: 2025-02-14
Form Type: SCHEDULE 13D/A
Source: 0001104659-25-014195
Chunk: 0

Company: NuCana plc
Filing Date: 2025-02-14
Form: SCHEDULE 13D/A
Chunk 0
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 shared power to dispose of these shares. Note in relation to Items 13: Percentage of class is calculated based on 98,630,000 ordinary shares outstanding as of September 30, 2024, as reported in Exhibit 99.1 in NuCana plc's Form 6-K filed with the SEC on November 25, 2024.

| SCHEDULE 13D |

| CUSIP No. | 67022C205 |

| 1                                                                  |                                                                         Maina Bhaman |
| 2                                                                  |                                                                                -a)(b |
| 3                                                                  |                                                                         SEC use only |
| 4                                                                  |                                                                                   OO |
| 5                                                                  |  Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e) |
| 6                                                                  |                                                                       UNITED KINGDOM |
| Number of Shares Beneficially Owned by Each Reporting Person With: |                                                                   7   4,987,975.00   
                                                                   8           0.00   
                                                                   9   4,987,975.00   
                                                                     10          0.00 |
| 11                                                                 |                                                                         4,987,975.00 |
| 12                                                                 | Check if the aggregate amount in Row (11) excludes certain shares (See Instructions) |
| 13                                                                 |                                                                                5.1 % |
| 14                                                                 |                                                                                   IN |

Comment for Type of Reporting Person: Note to Items 7 and 8: SP SAS, the management company of SC VI, may be deemed to have sole voting power, and Bhaman, a member of the investment committee of SC VI, may be deemed to have shared power to vote these shares. Note to Items 9 and 10: SP SAS, the management company of SC VI, may be deemed to have sole power to dispose of these shares, and Bhaman, a member of the investment committee of SC VI, may be deemed to have shared power to dispose of these shares. Note in relation to Items 13: Percentage of class is calculated based on 98,630,000 ordinary shares outstanding as of September 30, 2024, as reported in Exhibit 99.1 in NuCana plc's Form 6-K filed with the SEC on November 25, 2024.

| SCHEDULE 13D |

| CUSIP No. | 67022C205 |

| 1                                                                  |                                                                    Graziano Seghezzi |
|