Company: SION
Filing Date: 2025-02-07
Form Type: 424B4
Source: 0001193125-25-022709
Chunk: 226

Company: Sionna Therapeutics, Inc.
Filing Date: 2025-02-07
Form: 424B4
Chunk 226
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 business, we may lease
additional or alternate space. We believe that suitable additional or substitute space at commercially reasonable terms will be available as needed to accommodate any future expansion of our operations.

167

Legal Proceedings

From time to time, we may become involved in legal proceedings arising from the ordinary course of business. We record a liability for such matters when
it is probable that future losses will be incurred and that such losses can be reasonably estimated. Significant judgment by us is required to determine both probability and the estimated amount. Our management is currently not aware of any legal
matters that could have a material effect on our financial position, results of operations or cash flows.

168

MANAGEMENT Executive Officers, Key Employees and Directors The following table sets forth information regarding our executive officers, key employees and directors as of December 31, 2024.

| Name                            |     | Age |    |     | Position                                                  |
| Executive Officers:             |     |     |    |     |                                                           |
| Michael Cloonan, M.B.A.         |     |     | 53 |     | Chief Executive Officer, President and Director           |
| Charlotte McKee, M.D.           |     |     | 60 |     | Chief Medical Officer                                     |
| Elena Ridloff, C.F.A.           |     |     | 45 |     | Chief Financial Officer and Head of Corporate Development |
| Non-Employee Directors:         |     |     |    |     |                                                           |
| Paul Clancy, M.B.A.(2)(3)       |     |     | 63 |     | Chairperson of the Board                                  |
| Bruce Booth, D.Phil.(1)         |     |     | 50 |     | Director                                                  |
| H. Edward Fleming, Jr., M.D.(2) |     |     | 61 |     | Director                                                  |
| Lucian Iancovici, M.D.(1)       |     |     | 42 |     | Director                                                  |
| Joshua Resnick, M.D., M.B.A.    |     |     | 50 |     | Director                                                  |
| Marcella Kuhlman Ruddy, M.D.(3) |     |     | 62 |     | Director                                                  |
| Laurie Stelzer, M.B.A.(1)(2)    |     |     | 57 |     | Director                                                  |
| Peter A. Thompson, M.D.(3)      |     |     | 65 |