Company: BCDRF
Filing Date: 2025-01-08
Form Type: 424B5
Source: 0001193125-25-003514
Chunk: 0

Company: Banco Santander, S.A.
Filing Date: 2025-01-08
Form: 424B5
Chunk 0
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Filed Pursuant to Rule 424(b)(5)
Registration Statement No. 333-271955

PROSPECTUS SUPPLEMENT

(to prospectus dated May 16, 2023)

$2,000,000,000

Banco Santander, S.A.

$1,000,000,000 5.565% Senior Non Preferred Fixed Rate Notes due 2030

$1,000,000,000 6.033% Senior Non Preferred Fixed Rate Notes due 2035

We are offering $1,000,000,000 principal amount of 5.565% Senior Non Preferred Fixed Rate Notes due 2030 (the “2030 Fixed Rate
Notes”) and $1,000,000,000 principal amount of 6.033% Senior Non Preferred Fixed Rate Notes due 2035 (the “2035 Fixed Rate Notes” and, together with the 2030 Fixed Rate Notes, the “Notes”).

The 2030 Fixed Rate Notes will bear interest at a rate of 5.565% per year. From and including the date of issuance, interest will be
payable semi-annually in arrears on the 2030 Fixed Rate Notes on January 17 and July 17 of each year, beginning on July 17, 2025. The 2030 Fixed Rate Notes will be due on January 17, 2030.

The 2035 Fixed Rate Notes will bear interest at a rate of 6.033% per year. From and including the date of issuance, interest will be payable
semi-annually in arrears on the 2035 Fixed Rate Notes on January 17 and July 17 of each year, beginning on July 17, 2025. The 2035 Fixed Rate Notes will be due on January 17, 2035.

The Notes will be issued in minimum denominations of $200,000 and integral multiples of $200,000 in excess thereof.

The payment obligations of Banco Santander, S.A. (“Banco Santander”) in respect of principal under the Notes constitute direct,
unconditional, unsubordinated and unsecured senior non preferred obligations (créditos ordinarios no preferentes) of Banco Santander and, in accordance with Additional Provision 14.2 of Law 11/2015 (as defined herein), but subject to
any other ranking that may apply as a result of any mandatory provision of law (or otherwise), upon the insolvency of