Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119822
Chunk: 306

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 306
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 filed or furnished pursuant to Section 13(a) or 15(d) of the Exchange Act, as soon as reasonably practicable after we electronically file or furnish this
information to the SEC.

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MANAGEMENT The following sets forth certain information, as of the date of this prospectus, concerning the persons who are serving as our directors and executive officers. Executive Officers and Directors The following table sets forth the name, age and position of each of our directors and executive officers, as of April 1, 2025.

| Name                              |     | Age |    |     | Position(s)                                                  |
| Executive Officers:               |     |     |    |     |                                                              |
| Jaisim Shah(4)                    |     |     | 64 |     | Chief Executive Officer, President and Director              |
| Henry Ji, Ph.D.(4)                |     |     | 60 |     | Executive Chairperson and Director                           |
| Stephen Ma                        |     |     | 52 |     | Chief Financial Officer, Senior Vice President and Secretary |
| Non-employee Directors:           |     |     |    |     |                                                              |
| Jay Chun, M.D., Ph.D.(1)(2)(3)(4) |     |     | 61 |     | Director                                                     |
| Dorman Followwill(1)(2)(3)        |     |     | 61 |     | Director                                                     |
| Annu Navani(4)                    |     |     | 54 |     | Director                                                     |
| Yue Alexander Wu, Ph.D.(1)(2)(3)  |     |     | 61 |     | Director                                                     |

| (1) | Member of the Audit Committee. |

| (2) | Member of the Compensation Committee. |

| (3) | Member of the Nominating and Corporate Governance Committee. |

| (4) | Member of the Commercialization and Transaction Committee. |

Executive Officers Jaisim Shah .Mr. Shah has served as our Chief Executive Officer and President and a member of our Board since November 10, 2022. Prior to that, he served as Legacy Scilex’s President, Chief Executive Officer and a board member from March 2019 to November 2022. He has more than 25 years of global biopharma experience, including over 15 years in senior management leading business development, commercial operations, investor relations, marketing and medical affairs. He also served as the Chief Executive Officer and a