Company: NCNA
Filing Date: 2025-04-24
Form Type: F-1
Source: 0001193125-25-092131
Chunk: 15

Company: NuCana plc
Filing Date: 2025-04-24
Form: F-1
Chunk 15
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 | We are also offering to those purchasers, if any, whose purchase of the ADSs in this offering would result in such purchaser, together with its affiliates and certain related parties, beneficially owning more than 4.99% (or at the election of 
 the purchaser, 9.99%) of our outstanding ADSs immediately following consummation of this offering, the opportunity to purchase, if they so choose, Pre-Funded Warrants in lieu of the ADSs that would otherwise                                    
 result in ownership in excess of 4.99% (or 9.99%, as applicable) of our ADSs.                                                                                                                                                                      |

| The purchase price of each Pre-Funded Warrant and accompanying Warrants will equal the price per ADS and accompanying Warrants being sold to the public in this offering, minus the                    
 United States dollar equivalent of £0.01, based on the exchange rate on the date of pricing, and the exercise price of each Pre-Funded Warrant will be equal to the United States dollar equivalent of 
 £0.01, based on the exchange rate on the date of exercise.                                                                                                                                             |

| Each Pre-Funded Warrant will be immediately exercisable and may be exercised at any time until exercised in full. There is no expiration date for the Pre-Funded Warrants. There is no established trading market for the Pre-Funded Warrants, and we do not expect a market to develop. We do not intend to apply for a listing for 
 the Pre-Funded Warrants on any securities exchange or other nationally recognized trading system. Without an active trading market, the liquidity of the Pre-Funded                                                                                                                                                                  
 Warrants will be limited.                                                                                                                                                                                                                                                                                                            |

| To better understand the terms of the Pre-Funded Warrants, you should carefully read the “Description of Securities We Are Offering” section of this prospectus. |

| Series A Warrants offered by us | Each ADS and each Pre-Funded Warrant to purchase one ADS is being sold together with a Series A Warrant to purchase one ADS. Each Series A Warrant will have an exercise price equal to 125% of the combined 
 public offering price, will be exercisable at any time beginning on the Initial Exercise Date and will expire on the five-year anniversary of the Initial Exercise Date.                                     |

| This prospectus also relates to the offering of the ADSs issuable upon exercise of the Series A Warrants. Because we will issue a Series A Warrant for each ADS and for each 
 Pre-Funded Warrant sold