Company: SCLXW
Filing Date: 2025-12-16
Form Type: S-1
Source: 0001193125-25-319720
Chunk: 510

Company: Scilex Holding Co
Filing Date: 2025-12-16
Form: S-1
Chunk 510
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                                                                   |     |            |    (445 | ) |
| Warrant amendment and exercise as part of December 2024 RDO                                                                                                                                                                                                                                                                           |     |            |    (428 | ) |
| Settlement of December 2024 RDOPre-FundedWarrants                                                                                                                                                                                                                                                                                     |     |            |    (984 | ) |
| Change in fair value measurement                                                                                                                                                                                                                                                                                                      |     |            | (17,378 | ) |
| Ending Balance as of December 31, 2024                                                                                                                                                                                                                                                                                                |     | $          |  18,303 |   |

Warrant Liability Measurement

The derivative warrant liability was valued using the Black-Scholes option pricing model, which is considered to be Level 3 fair value measurement. The primary unobservable input utilized in determining the fair value of the warrant is the expected volatility of the Common Stock. The expected volatility assumption is based on the Company’s historical volatility, historical volatilities of comparable companies whose share prices are publicly

<div align='center'>F-23</div>

available as well as the implied volatility of the Public Warrants (see Note 9). A summary of the inputs used in valuing the derivative warrant liabilities is as follows:

|                |     | December 31, 2024 | PrivateWarrants |   |     |   | February2024 BDOFirmWarrants |   |     |   | April 2024RDOCommonWarrants |   |     |   | DepositWarrant |   |     |   | October2024NoteholderWarrants |   |     |   | December2024 RDOCommonWarrants(5yr) |   |     |   | December2024 RDOCommonWarrants(2.5yr) |   |
|:---------------|:----|:------------------|----------------:|:--|:----|:--|-----------------------------:|:--|:----|:--|----------------------------:|:--|:----|:--|---------------:|:--|:----|:--|------------------------------:|:--|:----|:--|------------------------------------:|:--|:----|:--|--------------------------------------:|:--|
| Exercise price |     | $                 |          402.50 |   |     | $ |                        59.50 |   |     | $ |                       38.50 |   |     | $ |           1.20 |   |     | $ |