Company: SNY
Filing Date: 2025-10-29
Form Type: 424B5
Source: 0001193125-25-255563
Chunk: 57

Company: Sanofi
Filing Date: 2025-10-29
Form: 424B5
Chunk 57
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, or the notes were used in,
or held for use in, the conduct of a business through a permanent establishment or a fixed base in France.

Pursuant to Article 235 ter ZD
of the French General Tax Code, purchases of equity securities, within the meaning of Article L.212-1 A of the French Monetary and Financial Code, of a French company listed on a regulated market of the EU or
on a foreign regulated market formally acknowledged by the French Autorité des Marchés Financiers are currently subject to a 0.4% French tax on financial transactions (the “FTFT”) provided that Sanofi’s market
capitalization exceeds €1 billion as of December 1 of the year preceding the taxation year. A list of companies whose market capitalization exceeds €1 billion as of December 1 of the year preceding the taxation
year, within the meaning of Article 235 ter ZD of the French General Tax Code, is published annually by the French tax authorities in their official guidelines. Transfer of the notes should remain outside the scope of the FTFT as notes do not
qualify as equity securities within the meaning of Article L.212-1 A of the French Monetary and Financial Code.

Wealth Tax

The French
wealth tax (impôt de solidarité sur la fortune) has been replaced with a French real estate wealth tax (impôt sur la fortune immobilière). French real estate wealth tax applies only to individuals and does not
generally apply to the Securities if the holder is a US resident, as defined pursuant to the provisions of the Treaty, provided that the individual does not own directly or indirectly a shareholding exceeding 10% of the financial rights and voting
rights.

United States Taxation

The
following discussion summarizes certain U.S. federal income tax considerations that may be relevant to you if you acquire the notes in this offering for cash at their “issue price” (i.e., the first price at which a

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substantial amount of the notes is sold for cash, excluding sales to bond houses, brokers or similar persons acting in the capacity of underwriters, placement agents or wholesalers) and are a
U.S. holder. For this purpose, you will be a U.S. holder if you are a beneficial owner of notes and are an individual who is a citizen or resident of the United States, an entity treated as a corporation for U.S. federal income tax purposes that is
organized under the laws of the United States, any