Company: AZN
Filing Date: 2025-06-26
Form Type: 11-K
Source: 0001683168-25-004771
Chunk: 11

Company: ASTRAZENECA PLC
Filing Date: 2025-06-26
Form: 11-K
Chunk 11
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ued at the NAV of shares held by the Plan at year end. The NAVs, provided by private equity fund managers as a practical
expedient, are based on the value of the underlying assets owned by the fund, minus its liabilities, and then divided by the number of
shares or units outstanding or multiplied by the Plan’s pro rata interest, in the case of non-unitized investments. The private
equity fund managers provide financial statements on a quarterly basis, which are used to value the securities based on the Plan’s

ownership percentage.

| 11 |

<div align='center'>ASTRAZENECA SAVINGS AND SECURITY PLAN

Notes to Financial Statements

December 31, 2024 and 2023

_______________</div>

| 4. | Fair Value Measurements, continued: |

The
preceding methods described may produce a fair value calculation that may not be indicative of net realizable value or reflective of
future fair values. Furthermore, although the Plan believes its valuation methods are appropriate and consistent with other market participants,
the use of different methodologies or assumptions to determine the fair value of certain financial instruments could result in a different
fair value measurement at the reporting date.

The following table lists the fair values of investments as of December 31, 2024 and 2023:

|                                             |     | Fair Value Measurements as of December 31, 2024: |               |     |         |             |     |         |   |     |         |   |
|:--------------------------------------------|:----|:-------------------------------------------------|--------------:|:----|:--------|------------:|:----|:--------|:--|:----|:--------|:--|
|                                             |     | Fair Value                                       |               |     | Level 1 |             |     | Level 2 |   |     | Level 3 |   |
| Common stock                                |     | $                                                |   139,748,329 |     | $       | 139,748,329 |     |         | – |     |         | – |
| Mutual funds                                |     |                                                  |    54,792,389 |     |         |  54,792,389 |     |         | – |     |         | – |
| Money market funds                          |     |                                                  |    18,400,867 |     |         |  18,400,867 |     |         | – |     |         | – |
| Total