Company: RVRC
Filing Date: 2025-08-13
Form Type: S-1/A
Source: 0001213900-25-075747
Chunk: 33

Company: Revium Rx.
Filing Date: 2025-08-13
Form: S-1/A
Chunk 33
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ents Will Be Judged Invalid. Some of the issued patents (issued patents cannot be invalid only provisional applications or      
 know how we now own or license may be determined to be invalid. If we have to defend the validity of any of our patents, the costs 
 of such defense could be substantial, and there is no guarantee of a successful outcome. In the event an important patent related  
 to our drug delivery technology is found to be invalid, we may lose competitive position and may not be able to receive royalties  
 for products covered in part or whole by that patent under license agreements.                                                     |

| ● | Danger of Being Charged                                                                                                                 
 With Infringement. Although we are not currently aware of any parties intending to pursue infringement claims against us, there         
 is the possibility that we may use a patented technology owned by another person and/or be charged with infringement. Defending or      
 indemnifying a third party against a charge of infringement can involve lengthy and costly legal actions, and there can be no guarantee 
 of a successful outcome. Biotechnology companies comparable to us in size and financial position have discontinued business after       
 losing infringement battles. If we or our partners were prevented from using or selling our human-use equipment, then our business      
 would be materially adversely affected.                                                                                                 |

| ● | Freedom to Operate Issues.                                                                                                         
 The competitive nature of our field of business and the fact that others have sought patent protection for technologies similar to 
 ours make these potential issues significant.                                                                                      |

In addition to patents,
we also rely on trade secrets and proprietary know-how. We try to protect this information with appropriate confidentiality and inventions
agreements with our employees, scientific advisors, consultants, and collaborators. We cannot be sure that these agreements will not
be breached, that we will be able to protect ourselves if they are breached, or that our trade secrets will not otherwise become known
or be independently discovered by competitors. If any of these events occur, then we face the potential of losing control over valuable
company information, which could negatively affect our competitive position.

We may be subject to legal claims against us or claims by us which could have a significant impact on our resulting financial performance.

At any given time, we may be subject to litigation,
the disposition of which may have an adverse effect upon our business, financial condition, or results of operation. Such claims include
but are not limited to and may arise from product liability and related claims if any of the products that we sell is faulty or contain
defects in materials