Company: CNTB
Filing Date: 2025-09-10
Form Type: POS AM
Source: 0001193125-25-200186
Chunk: 71

Company: Connect Biopharma Holdings Ltd
Filing Date: 2025-09-10
Form: POS AM
Chunk 71
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 have wrongfully used or 
 disclosed confidential information of their former employers or other third parties.                           |

| • |     | If our trademarks and trade names are not adequately protected, then we may not be able to build name 
 recognition in our markets of interest and our business may be adversely affected.                    |

| • |     | Any collaboration arrangements that we have or may enter into in the future may not be successful, which could 
 adversely affect our ability to develop and commercialize our products.                                        |

| • |     | Intellectual property rights do not necessarily address all potential threats. |

Risks Related to Doing Business in the PRC

| • |     | Changes in the political and economic policies of the PRC government may materially and adversely affect our                            
 business, financial condition and results of operations and may result in our inability to sustain our growth and expansion strategies. |

| • |     | The PRC government may intervene in or influence our operations in accordance with laws and regulations, which               
 could result in a material change in our operations and significantly and adversely impact the value of our Ordinary Shares. |

| • |     | Compliance with the PRC’s Data Security Law, Cybersecurity Review Measures, Personal Information                                                                                                             
 Protection Law, regulations and guidelines relating to the multi-level protection scheme and any other future laws and regulations may entail significant expenses and could materially affect our business. |

| • |     | PRC laws and regulations governing our current business operations are sometimes vague and uncertain, and                                                                                                                                    
 therefore, these risks may result in a material negative change in our subsidiaries’ operations, significant depreciation of the value of our Ordinary Shares, or a hindrance of our ability to offer or continue to offer our securities to 
 investors, which could cause the value of the securities of investors to decrease.                                                                                                                                                           |

| • |     | The approval of and the filing with the China Securities Regulatory Commission may be required under a PRC 
 regulation in connection with any future offerings of our securities in the U.S. market.                   |

| • |     | Certain PRC regulations may make it more difficult for us to pursue growth through acquisitions. Any failure                                                                                                                                       
 by us to comply with PRC anti-monopoly laws and regulations may result in governmental investigations or enforcement actions, litigation or claims against us and could have an adverse effect on our business, financial condition and results of 
 operations.                                                                                                                                                                                                                                        |

| • |     | Governmental control of currency conversion may limit our ability to remit funds out of the PRC and