Company: APM
Filing Date: 2025-11-17
Form Type: F-1
Source: 0001213900-25-111548
Chunk: 249

Company: Aptorum Group Ltd
Filing Date: 2025-11-17
Form: F-1
Chunk 249
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      |    48,599 |   |     |        |   33,447 |   |
| Net loss before income taxes       |     |                     |  (725,296 | ) |     |      |  (500,002 | ) |     |        | (225,294 | ) |
| Income taxes                       |     |                     |    17,939 |   |     |      |   114,403 |   |     |        |  (96,464 | ) |
| Net loss                           |     | $                   |  (743,235 | ) |     | $    |  (614,405 | ) |     | $      | (128,830 | ) |

147 Revenue Grant revenue was $531,729 for the year ended May 31, 2025 compared to $1,319,531 for the year ended May 31, 2024. The decrease was due to lower reimbursable direct labor, consulting and other development expenses for DiamiR’s CogniMIR ®product candidate corresponding to the depletion of available grant funding in January 2025. As of May 31, 2025, DiamiR has no remaining funds under its grants and grant revenues will decrease significantly or cease in future periods. Other revenue in the year ended May 31, 2025 consists of nonrecurring fees from a non-customer under a material transfer agreement. Research and Development Expenses DiamiR expenses the cost of research and development as incurred. Research and development expenses comprise costs incurred in performing research and development activities, including salaries and benefits, stock-based compensation, contracted services, and other external costs. Personnel costs include the majority of compensation paid to DiamiR’s Chief Executive Officer, representing his participation in research and development activities. Research and Development expense was $650,591 for the year ended May 31, 2025, compared to $1,156,860 for the year ended May 31, 2024. The decrease reflects a decrease of approximately $214,000 in salaries and benefits from employee salary reductions, a decrease of approximately $159,000 in stock based compensation expense, and decrease in other direct expenses for our CogniMIR ®product candidate, corresponding to the decrease in available grant funding. Decreased stock-based compensation primarily reflects greater vesting of options to DiamiR’s Chief Executive Officer in the year ended May 31, 2024. General and Administrative Expenses General and administrative expenses consist primarily