Company: SXTPW
Filing Date: 2025-07-16
Form Type: 424B4
Source: 0001213900-25-064472
Chunk: 4

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-07-16
Form: 424B4
Chunk 4
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| (1) | We have also agreed to reimburse the placement agent for certain of                                                                        
 its offering related expenses. In addition, we have agreed to issue the placement agent or its designees warrants to purchase a number     
 of shares of common stock equal to 7.5% of the shares of common stock sold in this offering (including the shares of common stock issuable 
 upon the exercise of the Pre-Funded Warrants), at an exercise price of $2.375 per share, which represents 125% of the public offering      
 price per share and accompanying Common Warrants. The registration statement of which this prospectus forms a part also registers the      
 offer and sale of these Placement Agent Warrants and the shares of common stock issuable upon exercise of these Placement Agent Warrants.  
 For a description of compensation to be received by the placement agent, see “Plan of Distribution” beginning on page                      
 34 of this prospectus for a description of the compensation to be received by the placement agent.                                         |

| (2) | Because there is no minimum number of securities or amount of proceeds                                                                  
 required as a condition to closing in this offering, the actual offering amount, placement agent fees and proceeds to us, if any, are   
 not presently determinable and may be substantially less than the total maximum offering amounts set forth above. We refer you to “Plan 
 of Distribution” on page 34 of this prospectus for additional information regarding placement agent compensation. The amount            
 of offering proceeds to us presented in this table does not give effect to any exercise of the Warrants or Pre-Funded Warrants.         |

We anticipate that delivery of the securities
against payment therefor will be made on or before July 16, 2025, subject to satisfaction of certain conditions.

<div align='center'>H.C. Wainwright & Co.

The date of this prospectus is July 15, 2025

TABLE OF CONTENTS</div>

| ABOUT THIS PROSPECTUS                             | ii |
| TRADEMARKS                                        | ii |
| GLOSSARY OF SELECTED TERMS                        | ii |
| USE OF PRODUCT VERSUS GENERIC NAMES               | iv |
| MARKET DATA                                       | iv |
| PROSPECTUS SUMMARY                                |  1 |
| SUMMARY OF THE OFFERING                           | 17 |
| RISK FACTORS                                      | 19 |
| SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS | 25 |
| USE OF PROCEEDS                                   | 25 |
|