Company: SXTPW
Filing Date: 2025-09-05
Form Type: 424B5
Source: 0001213900-25-085050
Chunk: 100

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-09-05
Form: 424B5
Chunk 100
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 prospectus. Our business, financial condition, results of operations and prospects
may have changed since that date.

Any statement contained in a document incorporated
or deemed to be incorporated by reference into this prospectus will be deemed to be modified or superseded for the purposes of this prospectus
to the extent that a statement contained herein, or in any other subsequently filed document which also is or is deemed to be incorporated
by reference herein, modifies or supersedes that statement. The modifying or superseding statement need not state it has modified or superseded
a prior statement or include any other information set forth in the document that it modifies or supersedes. The making of a modifying
or superseding statement is not an admission for any purposes that the modified or superseded statement, when made, constituted a misrepresentation,
an untrue statement of a material fact or an omission to state a material fact that is required to be stated or that is necessary to make
a statement not misleading in light of the circumstances in which it was made. Any statement so modified or superseded will not be deemed,
except as so modified or superseded, to constitute a part of this prospectus.

You may request, and we will provide you with,
a copy of these filings, at no cost, by calling us at (202) 327-5422 or by writing to us at the following address:

<div align='center'>60 Degrees Pharmaceuticals, Inc.

1025 Connecticut Avenue NW Suite 1000
Washington, D.C. 20036

Attn: Geoffrey Dow, Chief Executive Officer and
President

36

Up to $1,397,532

60 Degrees Pharmaceuticals, Inc.

Common Stock

PROSPECTUS SUPPLEMENT

September 5, 2025</div>