Company: DNLI
Filing Date: 2025-11-06
Form Type: 10-Q
Source: 0001714899-25-000193
Chunk: 399

Company: Denali Therapeutics Inc.
Filing Date: 2025-11-06
Form: 10-Q
Item: Part II, Item 3
Chunk 399
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 filed as Exhibit 10.1 to the Company’s Amendment No. 2 to the Registration Statement on Form S-1 (File No. 333-221522) filed with the Securities and Exchange Commission on December 7, 2017.

There is no arrangement or understanding between Mr. Van Hauwermeiren and any other persons pursuant to which Mr. Van Hauwermeiren was elected as a director. In addition, Mr. Van Hauwermeiren is not a party to any transaction, or series of transactions, required to be disclosed pursuant to Item 404(a) of Regulation S-K. The Board has determined that Mr. Van Hauwermeiren is independent under the applicable Nasdaq rules.

Departure of Chief Medical Officer

On November 6, 2025, the Company announced that Carole Ho, M.D., the Company's Chief Medical Officer and Head of Development, will be departing to pursue a new career opportunity. In connection with the announcement of Dr. Ho's departure, the Company also announced that Peter Chin, M.D., is assuming the role of Acting Chief Medical Officer and Head of Development. Dr. Chin joined the Company in 2019 and most recently served as Senior Vice President of the Enzyme TransportVehicle™ Franchise and Late-Stage Clinical Development. Dr. Ho will transition her responsibilities to Dr. Chin through late November 2025.

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ITEM 6.     EXHIBITS

EXHIBIT INDEX

Incorporated by ReferenceExhibitNumberDescriptionFormFile No.NumberFiling Date31.1Certification of Chief Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act.———Filed herewith31.2Certification of Chief Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act.———Filed herewith32.1*Certification of Chief Executive Officer pursuant to Section 906 of the Sarbanes-Oxley Act.———Furnished herewith32.2*Certification of Chief Financial Officer pursuant to Section 906 of the Sarbanes-Oxley Act.———Furnished herewith101.INSXBRL Instance Document - the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Incline XBRL document———Furnished herewith101.SCHInline XBRL Taxonomy Extension Schema Document.———Furnished herewith101.CALInline XBRL Taxonomy Extension Calculation Link