Company: WSBC
Filing Date: 2025-09-17
Form Type: 8-A12B
Source: 0001193125-25-206286
Chunk: 1

Company: WESBANCO INC
Filing Date: 2025-09-17
Form: 8-A12B
Chunk 1
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 Inc. (the “Registrant”). The descriptions of the Series B Preferred Stock and the Depositary Shares are incorporated by reference to the information set forth under the captions “Description of the Series B Preferred Stock” and “Description of the Depositary Shares,” in the prospectus supplement dated September 10, 2025 and filed pursuant to Rule 424(b)(5) under the Securities Act of 1933, as amended, in the form in which it was filed with the Securities and Exchange Commission on September 11, 2025, posting publicly on EDGAR on September 11, 2025. The prospectus supplement supplements the prospectus contained in the Registrant’s registration statement on Form S-3(File No. 333-270051)filed with the Securities and Exchange Commission on February 27, 2023. The Registrant has applied to list the Depositary Shares on the Nasdaq Global Select Market under the symbol “WSBCPB.” If the application is approved, we expect trading of the Depositary Shares on the Nasdaq Global Select Market to begin within the 30-day periodafter the initial delivery of the Depositary Shares. If any additional securities registered hereby are issued, a prospectus supplement relating to such securities will be filed with the Securities and Exchange Commission and will be incorporated herein by reference. Item 2. Exhibits.

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| 4.3 | Form of depositary receipt                                    
 representing the Depositary Shares (included in Exhibit 4.1). |

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SIGNATURE Pursuant to the requirements of Section 12 of the Securities Exchange Act of 1934, the Registrant has duly caused this registration statement to be signed on its behalf by the undersigned, thereto duly authorized.

| Date September 17, 2025 |     |     |     | WESBANCO, INC.                                                     |
|:------------------------|:----|:----|:----|:-------------------------------------------------------------------|
|                         |     | By: |     | /s/ Daniel K. Weiss, Jr.                                           |
|                         |     |     |     | Name: Daniel K. Weiss, Jr.                                         |
|                         |     |     |     | Title: Senior Executive Vice President and Chief Financial Officer |

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