Company: APM
Filing Date: 2025-07-15
Form Type: DRS
Source: 0001213900-25-063906
Chunk: 9

Company: Aptorum Group Ltd
Filing Date: 2025-07-15
Form: DRS
Chunk 9
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 PROSPECTUS This document, which forms part of a registration statement on Form S -4filed with the SEC by Aptorum, constitutes a prospectus of Aptorum under Section 5 of the Securities Act of 1933, as amended (the “Securities Act”), with respect to the shares of Aptorum Delaware common stock to be issued to DiamiR stockholders pursuant to the Merger Agreement. This document also constitutes a proxy statement of Aptorum under Section 14(a) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). It also constitutes a notice of special meeting of stockholders in lieu of annual meeting of shareholders of Aptorum. Aptorum has supplied all information contained in this proxy statement/prospectus relating to Aptorum, and DiamiR has supplied all such information relating to DiamiR. Aptorum and DiamiR have both contributed to the information related to the Merger contained in this proxy statement/prospectus. You should rely only on the information contained in this proxy statement/prospectus. Aptorum and DiamiR have not authorized anyone to provide you with information that is different from that contained in this proxy statement/prospectus. This proxy statement/prospectus is dated, 2025, and you should not assume that the information contained in this proxy statement/prospectus is accurate as of any date other than such date unless otherwise specifically provided herein. Further, you should not assume that the information contained in this proxy statement/prospectus is accurate as of any date other than the stated date. Neither the mailing of this proxy statement/prospectus to Aptorum shareholders nor the issuance by Aptorum Delaware of shares of its common stock pursuant to the Merger Agreement will create any implication to the contrary. This proxy statement / prospectus does not constitute an offer to sell, or a solicitation of an offer to buy, any securities, or the solicitation of a proxy, in any jurisdiction to or from any person to whom it is unlawful to make any such offer or solicitation in such jurisdiction. COMMONLY USED DEFINED TERMS Unless the context otherwise requires, in this registration statement references to: •“505(b)(2) Application” refers to an application for which one or more of the investigations relied upon by the applicant for approval “were not conducted by or for the applicant and for which the applicant has not obtained a right of reference or use from the person by or for whom the investigations were conducted” (21 U.S.C. 355(b)(