Company: PSTV
Filing Date: 2025-06-20
Form Type: S-1/A
Source: 0001193125-25-142935
Chunk: 16

Company: PLUS THERAPEUTICS, INC.
Filing Date: 2025-06-20
Form: S-1/A
Chunk 16
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. We may at any time in our sole discretion terminate the Purchase Agreement without fee, penalty or cost upon one
business day notice. There are no restrictions on future financings, rights of first refusal, participation rights, penalties or liquidated damages in the Purchase Agreement or Registration Rights Agreement, other than a prohibition on any
“equity line of credit”, “at-the-market offering” or other similar continuous offering in which we may offer, issue or sell shares of our common stock or securities convertible into shares of our common stock (or any combination
of units thereof) at a future determined price, subject to customary exceptions. Lincoln Park may not assign or transfer its rights and obligations under the Purchase Agreement.

As consideration for Lincoln Park’s commitment to purchase shares of our common stock upon the terms of and subject to satisfaction
of the conditions set forth in the Purchase Agreement, we agreed to pay $500,000 as an Initial Commitment Fee in cash, shares of our common stock or any combination thereof. In the event that part or all of the Initial Commitment Fee is paid in
Initial Commitment Shares, such Initial Commitment Shares must be

included in a registration statement to be filed with and declared effective by the SEC
on or prior to the date the Initial Commitment Fee is due registering under the Securities Act the resale by Lincoln Park of such Initial Commitment Shares. We have also agreed to pay an Additional Commitment Fee of $500,000, which we may elect to
pay in cash, shares of our common stock or any combination thereof, upon our receipt of $25.0 million aggregate gross proceeds from sales of common stock to Lincoln Park under the Purchase Agreement. In the

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event that part or all of the Additional Commitment Fee is paid in Additional Commitment Shares, such Additional Commitment Shares must be included in a registration statement to be filed with
and declared effective by the SEC on or prior to the date the Additional Commitment Fee is due registering under the Securities Act the resale by Lincoln Park of such Additional Commitment Shares.

As of June 17, 2025, there were 50,998,468 shares of our common stock outstanding, of which 50,901,216 shares of our common stock were held by
non-affiliates. If all of the 17,000,000 shares offered by Lincoln Park under this prospectus were issued and outstanding, such shares would represent approximately 25% of the total number of shares of our
common stock outstanding and approximately 25