Company: APM
Filing Date: 2025-01-03
Form Type: 424B5
Source: 0001213900-25-000606
Chunk: 21

Company: Aptorum Group Ltd
Filing Date: 2025-01-03
Form: 424B5
Chunk 21
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 020 80929299.
Additionally, copies of the documents incorporated herein by reference may be accessed at our website at www.aptorumgroup.com. The reference
to our website address does not constitute incorporation by reference of the information contained on or accessible through our website,
and you should not consider the contents of our website in making an investment decision with respect to our Class A Ordinary Shares.

You should rely only on the
information incorporated by reference or provided in this prospectus supplement or the accompanying prospectus. We have not authorized
anyone else to provide you with different information. You should not assume that the information in this prospectus supplement or the
accompanying prospectus is accurate as of any date other than the date on the front page of those documents.

<div align='center'>WHERE YOU CAN FIND MORE INFORMATION</div>

As permitted by SEC rules,
this prospectus omits certain information and exhibits that are included in the registration statement of which this prospectus forms
a part. Since this prospectus may not contain all of the information that you may find important, you should review the full text of these
documents. If we have filed a contract, agreement, or other document as an exhibit to the registration statement of which this prospectus
forms a part, you should read the exhibit for a more complete understanding of the document or matter involved. Each statement in this
prospectus, including statements incorporated by reference as discussed above, regarding a contract, agreement or other document is qualified
in its entirety by reference to the actual document.

We are subject to the information
reporting requirements of the Exchange Act that are applicable to foreign private issuers, and, in accordance with these requirements,
we file annual and current reports and other information with the SEC. You may inspect, read (without charge) and copy the reports and
other information we file with the SEC at the SEC’s Public Reference Room located at 100 F Street, N.E., Washington, D.C. 20549.
You may obtain information on the operation of the Public Reference Room by calling the SEC at 1-800-SEC-0330. The SEC also maintains
an internet website at www.sec.gov that contains our filed reports and other information that we file electronically with the SEC.

We maintain a corporate website
at www.aptorumgroup.com. Information contained on, or that can be accessed through, our website does not constitute a part of this prospectus.

<div align='center'>S-14

ENFORCEABILITY OF