Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 47

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 47
---
 solicitation of competing acquisition proposals and the conduct of Aptorum’s business between the date of signing the Merger Agreement  
 and the closing of the Merger. As a result, significant business decisions and transactions before the closing of the Merger require    
 the consent of DiamiR. Accordingly, Aptorum may be unable to pursue business opportunities that would otherwise be in its best interest 
 as a standalone company. Aptorum has invested significant time and resources in the transaction process and if the Merger Agreement is  
 terminated Aptorum will have a limited ability to continue its current operations without obtaining additional financing.               |

| ● | Aptorum’s collaborators and other business partners                                                                              
 and investors in general may view the failure to consummate the DiamiR Merger as a poor reflection on its business or prospects. |

| ● | Some of Aptorum’s collaborators and other business partners                                                        
 may seek to change or terminate their relationships with Aptorum as a result of the Merger or the failure thereof. |

| ● | As a result of the Merger, current and prospective employees                                                                       
 could experience uncertainty about their future roles within the Combined Company. This uncertainty may adversely affect Aptorum’s 
 ability to retain its key employees, who may seek other employment opportunities.                                                  |

| ● | Aptorum’s management team may be distracted from day-to-day 
 operations as a result of the Merger.                       |

| ● | Nasdaq could determine to delist Aptorum’s Class A                                                                                    
 ordinary shares which could have an adverse effect on the value of Aptorum’s ordinary shares and any future ability to raise capital. |

<div align='center'>23</div>

| ● | Subject to the terms and conditions in the Merger Agreement,                                                                     
 Aptorum may have to pay DiamiR a termination fee in the amount equal to the higher of (i) 70% of cash that Aptorum has as of the 
 date of termination and (ii) $2,000,000.                                                                                         |

In addition, if the Merger
Agreement is terminated and Aptorum’s board of directors determines to seek another business combination, it may not be able to
find a third party willing to provide equivalent or more attractive consideration than the consideration to be provided by each party
in the Merger. In such circumstances, Aptorum’s board of directors may elect to, among other things, divest all or a portion of
Aptorum’s business, and in such case, the consideration that Aptorum receives may be less attractive