Company: XOMAP
Filing Date: 2025-10-03
Form Type: 424B5
Source: 0001193125-25-230383
Chunk: 34

Company: XOMA Royalty Corp
Filing Date: 2025-10-03
Form: 424B5
Chunk 34
---
 such documents unless such exhibits are
specifically incorporated by reference herein), at no cost, by contacting us, either orally or in writing, at the following:

XOMA Royalty
Corporation

2200 Powell Street, Suite 310

Emeryville, California 94608

(510)
204-7200

Attn: Chief Financial Officer

Information about us, including our reports filed with the SEC, is available through our website at www.xoma.com. Such reports are accessible at no
charge through our website and are made available as soon as reasonably practicable after such material is filed with or furnished to the SEC. Our website and the information contained on that website, or connected to that website, are not
incorporated by reference in this prospectus supplement. We have authorized no one to provide you with any information that differs from that contained in this prospectus supplement. Accordingly, we take no responsibility for any other information
that others may give you. You should not assume that the information in this prospectus supplement is accurate as of any date other than the date of the front cover of this prospectus supplement.

S-29

PROSPECTUS

$200,000,000

### COMMON STOCK

### PREFERRED
STOCK

### DEPOSITARY SHARES

### DEBT SECURITIES

### WARRANTS

### SUBSCRIPTION RIGHTS

### CONTINGENT VALUE RIGHTS

### ROYALTY CERTIFICATES
UNITS

From time to time, we may issue, in one or more series or classes, up to $200,000,000 in aggregate principal amount of our common stock, preferred stock,
depositary shares, debt securities, warrants, subscription rights, contingent value rights, royalty certificates and/or units consisting of the foregoing, at prices and on terms that we will determine at the time of the offering.

This prospectus provides you with a general description of the securities we may offer. Each time we offer securities, we will provide specific terms of the
securities offered in a supplement to this prospectus. We may also authorize one or more free writing prospectuses to be provided to you in connection with these offerings. The prospectus supplement and any related free writing prospectus may also
add, update or change information contained in this prospectus. We may not sell any securities under this prospectus without delivery of the applicable prospectus supplement. If information in any prospectus supplement is inconsistent with the
information in this prospectus, then the information in that prospectus