Company: FENC
Filing Date: 2025-11-18
Form Type: S-8
Source: 0001104659-25-113660
Chunk: 6

Company: FENNEC PHARMACEUTICALS INC.
Filing Date: 2025-11-18
Form: S-8
Chunk 6
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 Company of Canada (incorporated 
 herein by reference to Schedule B to our Management Proxy Circular filed May 24, 2017).                                               |
| 4.5         |     | Fennec                                                                                                                                
 Pharmaceuticals Inc. 2020 Equity Incentive Plan (incorporated herein by reference to Schedule B to our Management Proxy Circular      
 filed April 25, 2025).                                                                                                                |
| 5.1         |     | Opinion                                                                                                                               
 of Counsel                                                                                                                            |
| 23.1        |     | Consent                                                                                                                               
 of Counsel (included in Exhibit 5.1)                                                                                                  |
| 23.2        |     | Consent of Independent Registered Public Accounting                                                                                   
 Firm                                                                                                                                  |
| 24.1        |     | Power of Attorney (included in the Signature                                                                                          
 Page hereto)                                                                                                                          |
| 107         |     | Filing Fee                                                                                                                            
 Table                                                                                                                                 |

Item 9. Undertakings.

The undersigned Registrant
hereby undertakes:

(1) To file, during any
period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

(i) To include any prospectus
required by section 10(a)(3) of the Securities Act;

(ii) To reflect in the
prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment
thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement.
Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered
would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be
reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in
volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the “Calculation of Registration
Fee” table in the effective Registration Statement; and

(iii) To include any
material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material
change to such information in the Registration Statement;

provided however,
that paragraphs (i) and (ii) above do not apply if the information required to be included in a post-effective amendment by
those paragraphs is contained in periodic reports filed with or furnished