Company: APM
Filing Date: 2025-10-14
Form Type: 424B5
Source: 0001213900-25-098635
Chunk: 3

Company: Aptorum Group Ltd
Filing Date: 2025-10-14
Form: 424B5
Chunk 3
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| Information Incorporated By Reference          |   31 |
| Where You Can Find More Information            |   32 |
| Enforceability of Civil Liabilities            |   33 |
| Indemnification For Securities Act Liabilities |   33 |

You should rely only on the information contained in this prospectus supplement and the accompanying prospectus. We have not authorized anyone else to provide you with additional or different information. We are offering to sell, and seeking offers to buy, ordinary shares only in jurisdictions where offers and sales are permitted. Neither we nor the Sales Agent are making an offer to sell any securities in jurisdictions where the offer or sale is not permitted. You should not assume that the information in this prospectus supplement or the accompanying prospectus is accurate as of any date other than the date on the front of those documents or that any document incorporated by reference is accurate as of any date other than its filing date.

No action is being taken in any jurisdiction outside the United States to permit a public offering of the ordinary shares or possession or distribution of this prospectus supplement or the accompanying prospectus in that jurisdiction. Persons who come into possession of this prospectus supplement or the accompanying prospectus in jurisdictions outside the United States are required to inform themselves about and to observe any restrictions as to this offering and the distribution of this prospectus supplement and the accompanying prospectus applicable to that jurisdiction. This prospectus supplement and the accompanying prospectus do not constitute an offer of, or an invitation to purchase, any securities in any jurisdiction in which such offer or invitation would be unlawful.

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ABOUT THIS PROSPECTUS SUPPLEMENT</div>

On December 19, 2022, we filed
with the SEC a registration statement on Form F-3 (File No. 333-268873) utilizing a shelf registration process relating to the securities
described in this prospectus supplement, which registration statement was declared effective on January 19, 2023. Under this shelf registration
process, we may, from time to time, sell up to $125 million in the aggregate of Class A Ordinary Shares, preferred shares, warrants, units,
and debt securities. We are selling $2,000,000 worth of Class A Ordinary Shares in this offering and as of the date of this prospectus
supplement.

This document is in two parts.
The first part is this prospectus supplement, which describes the specific terms of this ordinary shares offering and also adds to and