Company: PNBK
Filing Date: 2025-06-04
Form Type: 424B5
Source: 0001437749-25-019364
Chunk: 0

Company: PATRIOT NATIONAL BANCORP INC
Filing Date: 2025-06-04
Form: 424B5
Chunk 0
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Filed pursuant to Rule 424(b)(5)

Registration No. 333-287283

PROSPECTUS SUPPLEMENT

(To Prospectus dated May 22, 2025)

<div align='center'>PATRIOT NATIONAL BANCORP, INC.

8,524,160 Shares of Common Stock</div>

We are offering 8,524,160 shares, referred to as the “Shares,” of our common stock, par value $0.01 per share, or “Common Stock,” directly to certain accredited investors, referred to as the “purchasers,” pursuant to this prospectus supplement and the accompanying prospectus.

Our Common Stock is listed on The Nasdaq Global Market, or “Nasdaq,” under the symbol “PNBK”. On June 3, 2025, the last reported sale price of our Common Stock, as reported on Nasdaq, was $1.17 per share.

Investing in our securities involves a high degree of risk. Before buying any securities, you should carefully read the discussion of the risks of investing in our securities in“Risk Factors”beginning on page S-3 of this prospectus supplement and page 4 of the accompanying prospectus and any other risk factors contained in the documents incorporated by reference into this prospectus supplement and the accompanying prospectus.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus supplement or the accompanying prospectus. Any representation to the contrary is a criminal offense.

The purchase price of each Share of Common Stock to the purchasers identified in the securities purchase agreement, dated as of June 3, 2025, by and among us and the purchasers listed on the signature pages thereto is $1.25 per Share. The Shares of Common Stock are being offered directly to investors without a placement agent or underwriter. We are not paying underwriting discounts or commissions in connection with this offering.

|                                                           |     | Per Share |     |       Total |
| Public offering price and proceeds to us, before expenses |     |     $1.25 |     | $10,655,200 |

We anticipate that delivery of the Shares of Common Stock against payment will be made on or about June 5, 2025, subject to satisfaction of customary closing conditions.

The date of this prospectus supplement is June 4, 2025

<div align='center'>TABLE OF CONTENTS

PROSPECTUS SUPPLEMENT</