Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 251

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 251
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 who has continuously owned at least three percent (3%) of outstanding Comerica common stock for at least three years
may nominate and include in Comerica’s annual meeting proxy materials director nominees constituting up to the greater of two (2) individuals or twenty percent (20%) of the Comerica board of directors. Such nominations are subject to the
disclosure, eligibility and procedural requirements as set forth in Comerica’s bylaws, including the advance notice procedures set forth above.

If
the first merger is completed, Comerica will not hold its annual meeting of shareholders in 2026. Instead, Fifth Third will hold an annual meeting of shareholders in 2026.

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WHERE YOU CAN FIND MORE INFORMATION Fifth Third and Comerica file annual, quarterly and current reports, proxy statements and other information with the SEC. The SEC maintains an Internet site that contains reports, proxy and information statements, and other information regarding issuers that file electronically with the SEC, including both Fifth Third and Comerica, which can be accessed at http://www.sec.gov. In addition, documents filed with the SEC by Fifth Third including the registration statement on Form S-4,of which this joint proxy statement/prospectus forms a part, will be available free of charge by accessing Fifth Third’s website at https://ir.53.com under “SEC Filings” or, alternatively, by directing a request by telephone or mail to Fifth Third Bancorp, 38 Fountain Square Plaza, MD 10907F, Cincinnati, Ohio 45263, (615) 744-8219,and documents filed with the SEC by Comerica will be available free of charge by accessing Comerica’s website at http://www.investor.comerica.com under the tab “SEC Filings” or, alternatively, by directing a request by telephone or mail to Comerica Bank Tower, 1717 Main Street, MC 6404, Dallas, TX 75201, (833) 571-0486.The web addresses of the SEC, Fifth Third and Comerica are included as inactive textual references only. Except as specifically incorporated by reference into this joint proxy statement/prospectus, information on those web sites is not part of this joint proxy statement/prospectus. Fifth Third has filed a registration statement on Form S-4under the Securities Act with the SEC with respect to Fifth Third’s securities to be issued in connection with the first merger. This document constitutes the prospectus of Fifth Third filed as part of