Company: BDRX
Filing Date: 2025-05-01
Form Type: DRS
Source: 0001214659-25-006756
Chunk: 108

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-05-01
Form: DRS
Chunk 108
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 ADR or ADRs, or an interest therein,
after being so notified, such ADR holder and any beneficial owner are deemed to agree to such amendment and to be bound by the Deposit
Agreement as so amended. No amendment, however, will impair your right to surrender your Depositary Shares and receive the underlying
securities, except in order to comply with mandatory provisions of applicable law.

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Any amendments or supplements that (i) are
reasonably necessary (as agreed by us and the depositary) in order for (a) the Depositary Shares to be registered on Form F-6 under the
Securities Act or (b) the Depositary Shares or Ordinary Shares to be traded solely in electronic book-entry form and (ii) do not in either
such case impose or increase any fees or charges to be borne by ADR holders, shall be deemed not to prejudice any substantial rights of
ADR holders or beneficial owners. Notwithstanding the foregoing, if any governmental body or regulatory body should adopt new laws, rules
or regulations that would require amendment or supplement of the Deposit Agreement or the form of ADR to ensure compliance therewith,
we and the depositary may amend or supplement the Deposit Agreement and the form of ADR (and all outstanding ADRs) at any time in accordance
with such changed laws, rules or regulations. Such amendment or supplement to the Deposit Agreement in such circumstances may become effective
before a notice of such amendment or supplement is given to ADR holders or within any other period of time as required for compliance.

Notice of any amendment to the Deposit Agreement
or form of ADRs shall not need to describe in detail the specific amendments effectuated thereby, and failure to describe the specific
amendments in any such notice shall not render such notice invalid, provided, however, that, in each such case, the notice given to the
ADR holders identifies a means for ADR holders and beneficial owners to retrieve or receive the text of such amendment (i.e.,upon
retrieval from the SEC’s, the depositary’s or our website or upon request from the depositary).

How may the Deposit Agreement be terminated?

The depositary may at any time, and shall
at our written direction, terminate the Deposit Agreement and the ADRs by mailing notice of such termination to the registered holders
of ADRs at least thirty (30) days prior to the date fixed in such notice for such termination; provided, however, if the depositary