Company: IMRX
Filing Date: 2025-09-03
Form Type: S-3
Source: 0001104659-25-086561
Chunk: 3

Company: Immuneering Corp
Filing Date: 2025-09-03
Form: S-3
Chunk 3
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 passed upon the adequacy or accuracy of this prospectus. Any representation to the contrary is a criminal offense.**

<div align='center'>The date of this prospectus is , 2025.</div>

TABLE OF CONTENTS

TABLE OF CONTENTS

| ​ | ABOUT THIS PROSPECTUS                                           | ​ | ​ | ​ | ​ |  1 | ​ | ​ |
| ​ | SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS               | ​ | ​ | ​ | ​ |  2 | ​ | ​ |
| ​ | WHERE YOU CAN FIND MORE INFORMATION; INCORPORATION BY REFERENCE | ​ | ​ | ​ | ​ |  3 | ​ | ​ |
| ​ | THE COMPANY                                                     | ​ | ​ | ​ | ​ |  5 | ​ | ​ |
| ​ | RISK FACTORS                                                    | ​ | ​ | ​ | ​ |  6 | ​ | ​ |
| ​ | USE OF PROCEEDS                                                 | ​ | ​ | ​ | ​ |  7 | ​ | ​ |
| ​ | DESCRIPTION OF SECURITIES                                       | ​ | ​ | ​ | ​ |  8 | ​ | ​ |
| ​ | PRIVATE PLACEMENT OF SECURITIES                                 | ​ | ​ | ​ | ​ | 16 | ​ | ​ |
| ​ | SELLING STOCKHOLDERS                                            | ​ | ​ | ​ | ​ | 18 | ​ | ​ |
| ​ | PLAN OF DISTRIBUTION                                            | ​ | ​ | ​ | ​ | 21 | ​ | ​ |
| ​ | LEGAL MATTERS                                                   | ​ | ​ | ​ | ​ | 23 | ​ | ​ |
| ​ | EXPERTS                                                         | ​ | ​ | ​ | ​ | 23 | ​ | ​ |

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TABLE OF CONTENTS

### ABOUT THIS PROSPECTUS
This prospectus is part of a registration statement that we filed with the U.S. Securities and Exchange Commission, or the SEC, using a “shelf” registration process. By using a shelf registration statement, the selling securityholders may, from time to time, sell up to 9,177,209 shares of Class A common stock in one or more offerings as described in this prospectus. In connection with the offer and sale of securities by the selling securityholders, the selling securityholders may provide a prospectus supplement to this prospectus that contains specific information about the securities being offered and sold and the specific terms of that offering. We