Company: EDSA
Filing Date: 2025-09-05
Form Type: CORRESP
Source: 0001171843-25-005749
Chunk: 0

Company: Edesa Biotech, Inc.
Filing Date: 2025-09-05
Form: CORRESP
Chunk 0
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<div align='center'>Edesa Biotech, Inc.

100 Spy Court

Markham, Ontario, Canada L3R 5H6</div>

September 5, 2025

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

| Re: | Edesa Biotech, Inc. |

Registration Statement on Form S-3 (File No. 333-288966)

Filed on July 25, 2025

Ladies and Gentlemen:

In accordance with Rule 461 under
the Securities Act of 1933, as amended, Edesa Biotech, Inc. (the “”) hereby requests that the above-referenced
Registration Statement (the “”) be declared effective by the Securities and Exchange Commission
at 4:00 p.m., Eastern Time, on September 9, 2025, or as soon as practicable thereafter.

Please call Tracy Buffer of Lowenstein Sandler LLP
at (973) 597-2434 to confirm the effectiveness of the Registration Statement or with any questions.

| Very truly yours,              |
| EDESA BIOTECH, INC.            |
| By: /s/ Peter Weiler           |
| Name: Peter Weiler             |
| Title: Chief Financial Officer |