Company: SNY
Filing Date: 2025-10-29
Form Type: 424B5
Source: 0001193125-25-255563
Chunk: 44

Company: Sanofi
Filing Date: 2025-10-29
Form: 424B5
Chunk 44
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 (Code General des impôts).                                                     |

| • |     | The holder is a fiduciary or partnership or an entity that is not the sole beneficial owner of the payment of the                                                                                                                                    
 principal of, or any interest on, any Note, and the laws of the Republic of France require the payment to be included in the income of a beneficiary or settlor for tax purposes with respect to such fiduciary or a member of such partnership or a 
 beneficial owner who would not have been entitled to such additional amounts had it been the holder of such security (Section 1007).                                                                                                                 |

These provisions will also apply to any taxes or governmental charges imposed by any jurisdiction in which a successor to the Issuer by merger is organized or if we otherwise change the jurisdiction in which the Issuer is organized or resident for tax purposes, except that the name of the jurisdiction of the successor, or our new jurisdiction of organization or residency for tax purposes, will be substituted for the Republic of France. Redemption As explained below, we may redeem the Notes before they mature in the circumstances and at the prices described below, including if certain tax-relatedevents occur. This means we may repay them early. You have no right to require us to redeem the Notes. Notes will stop bearing interest on the applicable redemption date, even if you do not collect your money. Optional Redemption The floating rates notes are not redeemable prior to maturity, other than as set forth in “ — Tax Redemption” below. Unless otherwise specified in the pricing term sheet, the below provisions on optional redemption will apply to the Fixed Rate Notes. Prior to October 3, 2028, in the case of the 2028 Fixed Rate Notes and September 3, 2032, in the case of the 2032 Fixed Rate Notes (each a “Par Call Date”) the Issuer may redeem the relevant series of Fixed Rate Notes at its option, in whole or in part, at any time and from time to time, at a redemption price (expressed as a percentage of principal amount and rounded to three decimal places) equal to the greater of: (1) (a) the sum of the present values of the Remaining Scheduled Payments of principal and interest thereon discounted to the redemption date (assuming the relevant Notes matured on the Par Call Date) on a semi-annual basis (assuming a 360-dayyear consisting of twelve 30-daymonths) at the Treasury Rate plus (i) 0.050% (or 5 basis points), in