Company: CMA
Filing Date: 2025-08-05
Form Type: 424B5
Source: 0001193125-25-173600
Chunk: 43

Company: COMERICA INC
Filing Date: 2025-08-05
Form: 424B5
Chunk 43
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 to the liquidation preference of such share. Under regulations adopted by the Federal Reserve, if the holders of any series of preferred stock are or become entitled to vote for the election of directors, such series will be deemed a “class of voting securities” and a company holding 25% or more of the series, or 5% or more if it otherwise has the ability to exercise a “controlling influence” over us, may then be subject to regulation as a bank holding company in accordance with the Bank Holding Company Act of 1956, as amended. In addition, at the time the series is deemed a class of voting securities,

| • |     | any other bank holding company may be required to obtain the approval of the Federal Reserve (or any successor                         
 bank regulatory authority that may become our applicable federal banking agency) to acquire or retain more than 5% of that series; and |

| • |     | any other persons other than a bank holding company may be required to obtain the                                                                                                        
 non-objection of the Federal Reserve (or any successor bank regulatory authority that may become our applicable federal banking agency) to acquire or retain 10% or more of that series. |

Other Voting Rights So long as any shares of Series B Preferred Stock remain outstanding, the affirmative vote or consent of the holders of at least two-thirdsof all outstanding shares of the Series B Preferred Stock voting separately as a class, will be required to:

| • |     | amend, alter or repeal the provisions of our Certificate of Incorporation (including the certificate of 
 designation creating the Series B Preferred Stock), or our Amended and Restated Bylaws, whether by      |

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| merger, consolidation or otherwise, so as to adversely affect the powers, preferences, privileges or special rights of the Series B Preferred Stock; provided, that any of the following will not 
 be deemed to adversely affect such powers, preferences, privileges or special rights:                                                                                                             |

| • |     | increases in the amount of the authorized common stock or, except as provided below, preferred stock; |

| • |     | increases or decreases in the number of shares of any series of preferred stock ranking equally with or junior to 
 the Series B Preferred Stock; or                                                                                  |

| • |     | the authorization, creation and issuance of other classes or series of capital stock (or securities convertible 
 or exchangeable into such capital stock) ranking equally with or junior to the Series B Preferred Stock;        |

| • |     | amend or