Company: TELO
Filing Date: 2025-11-20
Form Type: PREM14A
Source: 0001493152-25-024463
Chunk: 208

Company: Telomir Pharmaceuticals, Inc.
Filing Date: 2025-11-20
Form: PREM14A
Chunk 208
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vant (after surgery) or Neoadjuvant (before surgery) treatment. We didn’t find any of these therapies for early stages of breast cancer that had only a branded therapy available. Usually, anthracyclines (like doxorubicin or epirubicin) treatments are used for adjuvant and neoadjuvant treatment of early stages breast cancers.

When generic versions of anthracyclines (like doxorubicin or epirubicin) are available, prices fall dramatically, so for pricing of a new branded anthracycline-based drug (or one not yet generic), we need a reference branded comparator that:

| ▪ | Still                                                  
 holds patent protection or uses a branded formulation, |

| ▪ | Belongs                                                         
 to the same class (anthracycline or anthracycline-derived), and |

| ▪ | It                                   
 has publicly available pricing data. |

Our Price Benchmark for the breast cancer treatment is Liposomal Doxorubicin (Anthracycline, liposomal formulation of doxorubicin). Doxil is a version of the chemotherapy medication doxorubicin that is covered in a protective coating, which allows it to avoid destruction by the body’s immune system and remain in the body for a longer amount of time. As a result, Doxil has more time to reach the tumor tissue, where the medication is then slowly released. Doxorubicin liposomal interferes with the growth of cancer cells and slows their spread in the body by inhibiting DNA synthesis and causing the production of harmful free radicals.

According to Drugs.com price-guide, one listing shows: for DOXIL (doxorubicin liposomal) 2 mg/mL: a 10 mL vial (20 mg) listed at US $320.63. And for a 25 mL vial (50 mg) ~ US $1,652.83 at one snapshot 12.

For modeling a full treatment course: suppose a patient of body surface area (BSA) 1.8 sqm receives the standard 50 mg/sqm, that’s 90 mg each cycle (50 ×1.8). That might equate to roughly two 50 mg vials (or one 100 mg equivalent) each cycle. If each 50 mg vial costs $1,650 (per above), two vials $3,300 per cycle. If treatment continues for, say, 6 cycles, $19,800 in drug cost alone.