Company: SCLXW
Filing Date: 2025-05-07
Form Type: POS AM
Source: 0001193125-25-115088
Chunk: 449

Company: Scilex Holding Co
Filing Date: 2025-05-07
Form: POS AM
Chunk 449
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 and other information as soon as reasonably practicable after they are electronically filed with, or furnished to, the SEC. The information contained on, or that may be accessed through, our website is not part of, and is not incorporated into, this prospectus and the inclusion of our website address in this prospectus is an inactive textual reference only.

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INDEX TO CONSOLIDATED FINANCIAL STATEMENTS

| Report of Independent Registered Public Accounting Firm (PCAOB ID: 207)                                     
 Consolidated Balance Sheets as of December 31, 2024 and 2023                                                
 Consolidated Statements of Operations and Comprehensive Loss for the Years ended December 31, 2024 and 2023 |     | F-2 
 F-3 
 F-4 |
|:------------------------------------------------------------------------------------------------------------|:----|:----|
| Consolidated Statements of Stockholders’ Equity / (Deficit) for the Years ended December 31, 2024 and 2023  |     | F-5 |
| Consolidated Statements of Cash Flows for the Years ended December 31, 2024 and 2023                        |     | F-6 |
| Notes to Consolidated Financial Statements                                                                  |     | F-8 |

F-1

<div align='center'>**Report of Independent Registered Public Accounting Firm**</div>

To the Board of Directors and stockholders of

Scilex Holding Company

### Opinion on the Financial Statements
We have audited the accompanying consolidated balance sheets of Scilex Holding Company and Subsidiaries (the “Company”) as of December 31, 2024 and 2023, and the related consolidated statements of operations and comprehensive loss, stockholders’ equity/(deficit), and cash flows for each of the two years in the period ended December 31, 2024, and the related notes (collectively referred to as the “consolidated financial statements”). In our opinion, the consolidated financial statements present fairly, in all material respects, the financial position of the Company as of December 31, 2024 and 2023, and the results of their operations and cash flows for each of the two years in the period ended December 31, 2024, in conformity with accounting principles generally accepted in the United States of America.

#### Going Concern
The accompanying consolidated financial statements have been prepared assuming that the entity will continue as a going concern. As discussed in Note 2 to the consolidated financial statements, the