Company: ERAS
Filing Date: 2025-08-20
Form Type: CORRESP
Source: 0001193125-25-184070
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Company: Erasca, Inc.
Filing Date: 2025-08-20
Form: CORRESP
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Erasca, Inc. 3115 Merryfield Row, Suite 300 San Diego, CA 92121 August 20, 2025 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549

| Re: | Erasca, Inc. |

Registration Statement on Form S-3 File No. 333-289537 To the addressees set forth above: Pursuant to Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, the undersigned, on behalf of Erasca, Inc., respectfully requests that the effective date of the Registration Statement on Form S-3referred to above be accelerated so that it will become effective at 4:00 P.M. Eastern Time on August 22, 2025, or as soon as practicable thereafter. If you have any questions or require additional information, please contact Matthew T. Bush, Esq. of Latham & Watkins LLP at (858) 523-3962.Thank you for your assistance and cooperation in this matter.

| Very truly yours, |     |                                                  |
| ERASCA, INC.      |     |                                                  |
| By:               |     | /s/ Jonathan E. Lim                              |
|                   |     | Jonathan E. Lim, M.D.                            |
|                   |     | Chairman, Chief Executive Officer and Co-Founder |

| cc: | Ebun S. Garner, Erasca, Inc. |

Cheston J. Larson, Latham & Watkins LLP Matthew T. Bush, Latham & Watkins LLP