Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 259

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 259
---
 not required to obtain approvals from
Chinese authorities to operate our business or list on the U.S. exchanges and offer securities; specifically, none of Mios or Scipio is
currently required to obtain any permission or approval from the China Securities Regulatory Commission (“CSRC”), Cyberspace
Administration of China (“CAC”) or any other PRC governmental authority to operate its business or for us to continue to list
our securities on a U.S. securities exchange or issue securities to foreign investors. However, there is no assurance that there will
not be any changes in the economic, political and legal environment in Hong Kong in the future. Should the PRC government choose to affect
operations of any company with any level of operations in Hong Kong, or should certain PRC laws and regulations or these statements or
regulatory actions become applicable to the VIE in the future. Such governmental actions: (i) could significantly limit or completely
hinder our ability to continue our operations; (ii) could significantly limit or hinder our ability to offer or continue to offer our
Class A Ordinary Shares to investors; and (iii) may cause the value of our Class A Ordinary Shares to significantly decline or be worthless.

We are also aware that recently,
the PRC government initiated a series of regulatory actions and statements to regulate business operations in certain areas in mainland
China with little advance notice, including cracking down on illegal activities in the securities market, enhancing supervision over mainland
Chinese companies listed overseas using variable interest entity structure, adopting new measures to extend the scope of cybersecurity
reviews, and expanding the efforts in anti-monopoly enforcement. Nevertheless, since these statements and regulatory actions are new,
it is highly uncertain how soon the legislative or administrative regulation making bodies will respond and what existing or new laws
or regulations or detailed implementations and interpretations will be modified or promulgated, if any. It is also highly uncertain what
the potential impact such modified or new laws and regulations will have on the VIEs’ daily business operation, and the continued
listing of our Class A Ordinary Shares on a U.S. or other foreign exchanges. If any or all of the foregoing were to occur, it may significantly
limit or completely hinder our ability to complete this offering or cause the value of our Class A Ordinary Shares to significantly decline
or become worthless. See “Risk Factors - Risks Related to Our Corporate Structure” and “Risk Factors - Risks Relating
to Doing Business in Hong Kong

<div align='center'>144

DiamiR