Company: JPC
Filing Date: 2025-06-10
Form Type: N-14 8C/A
Source: 0001999371-25-007489
Chunk: 9

Company: Nuveen Preferred & Income Opportunities Fund
Filing Date: 2025-06-10
Form: N-14 8C/A
Chunk 9
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 the United States.                                        |

| ● | To                                                                                 
 vote by telephone, please call the toll-free number located on your proxy card and 
 follow the recorded instructions, using your proxy card as a guide.                |

| ● | To                                                                                
 vote over the Internet prior to the Meetings, go to the Internet address provided 
 on your proxy card and follow the instructions, using your proxy card as a guide. |

You will be able to attend and participate in the Meetings online, vote your shares electronically and submit your questions during the Meetings by visiting: meetnow.global/MNDAGMQ at the Meeting date and time described in the enclosed Joint Proxy Statement/Prospectus. To participate in the Meetings, you will need to log on using the control number from your proxy card or meeting notice. The control number can be found in the shaded box. There is no physical location for the Meetings.

If you hold your shares through an intermediary, you will need to register at least three business days prior to the Meetings by following the instructions in the enclosed Joint Proxy Statement/Prospectus.

| Mark                         
 L. Winget                    
 Vice President and Secretary 
 The Nuveen Closed-End Funds  |

<div align='center'>ii</div>

The information contained in this Joint Proxy Statement/Prospectus is not complete and may be changed. We may not sell these securities until the registration statement filed with the Securities and Exchange Commission is effective. This Joint Proxy Statement/Prospectus is not an offer to sell these securities, and it is not soliciting an offer to buy these securities, in any jurisdiction where the offer or sale is not permitted.

<div align='center'>SUBJECT TO COMPLETION, DATED June 9, 2025

NUVEEN FUNDS
333 WEST WACKER DRIVE CHICAGO, ILLINOIS 60606
(800) 257-8787

JOINT PROXY STATEMENT/PROSPECTUS

NUVEEN PREFERRED SECURITIES & INCOME OPPORTUNITIES FUND (JPI)
AND
NUVEEN PREFERRED & INCOME OPPORTUNITIES FUND (JPC)
(EACH, A “FUND” AND TOGETHER, THE “FUNDS”)

[●], 2025</div>

This Joint Proxy Statement/Prospectus is being furnished to common shareholders of Nuveen Preferred Securities & Income Opportunities Fund ( “Target Fund”) and preferred shareholders of Nuveen Preferred & Income Opportunities Fund (the “