Company: CF
Filing Date: 2025-11-19
Form Type: 424B2
Source: 0001104659-25-113972
Chunk: 6

Company: CF Industries Holdings, Inc.
Filing Date: 2025-11-19
Form: 424B2
Chunk 6
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the other risks and uncertainties described in this prospectus supplement and the accompanying prospectus and included from time to time in our filings with the SEC.

You should also carefully read the factors described in the section entitled “Risk Factors” and in other cautionary statements in this prospectus supplement and in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024, filed with the SEC on February 20, 2025 (the “Annual Report”), any Quarterly Reports on Form 10-Q filed with the SEC since the filing of the Annual Report and our other filings with the SEC that are incorporated by reference into this prospectus supplement for a description of certain risks that could, among other things, cause our actual results to differ from those expressed in forward-looking statements.

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TABLE OF CONTENTS

### SUMMARY
This summary highlights important information about this offering and some of the information in this prospectus supplement, the accompanying prospectus and the documents incorporated by reference. It does not contain all the information that you should consider before making a decision to invest in the notes. You should read carefully the more detailed information in this prospectus supplement and the accompanying prospectus and the information incorporated by reference into this prospectus supplement and the accompanying prospectus, including “Risk Factors” beginning on page S-11 of this prospectus supplement and on page 3 of the accompanying prospectus and the information set forth in the section entitled “Risk Factors” in the Annual Report, as well as the other information set forth in our other filings under the Exchange Act that is incorporated herein by reference.

#### Our Company
Our mission is to provide clean energy to feed and fuel the world sustainably. With our employees focused on safe and reliable operations, environmental stewardship, and disciplined capital and corporate management, we are on a path to decarbonize our ammonia production network to enable low-carbon hydrogen and nitrogen products for energy, fertilizer, emissions abatement and other industrial activities. Our manufacturing complexes in the United States, Canada and the United Kingdom, an extensive storage, transportation and distribution network in North America, and logistics capabilities enabling a global reach underpin our strategy to leverage our unique capabilities to accelerate the world’s transition to clean energy. Our principal customers are cooperatives, retailers, independent fertilizer distributors, traders, wholesalers and industrial users. Our core product is anhydrous ammonia (ammonia), which contains 82% nitrogen and 18% hydrogen. Products derived from