Company: TVRD
Filing Date: 2025-05-30
Form Type: S-1
Source: 0001104659-25-054853
Chunk: 139

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-05-30
Form: S-1
Chunk 139
---
 | $    |  3,721 | ​ | $      |   -610 |   |   -16.4 | % |
| General and administrative | ​ |                    |  1,243 | ​ |      |    727 | ​ |        |    516 |   |    71.0 | % |
| Total operating expenses   | ​ |                    |  4,354 | ​ |      |  4,448 | ​ |        |    -94 |   |    -2.1 | % |
| Loss from operations       | ​ |                    | -4,354 | ​ |      | -4,448 | ​ |        |     94 |   |    -2.1 | % |
| Interest income            | ​ |                    |    275 | ​ |      |    246 | ​ |        |     29 |   |    11.8 | % |
| Other expense              | ​ |                    | -5,500 | ​ |      |      — | ​ |        | -5,500 |   |     n/a | ​ |
| Net loss                   | ​ | $                  | -9,579 | ​ | $    | -4,202 | ​ | $      | -5,377 |   |   128.0 | % |

Research and Development Expenses Research and development expenses for the three months ended March 31, 2025 and 2024 were comprised of the following (in thousands, except percentages):

| ​                                                    
 ​                                                    
 ​                                                    
 ​                                                    
 Direct research and development expenses by program: 
 TTI-101:                                             | ​ 
 ​ 
 ​ | ​                  
 Three Months Ended 
 March 31,          
 2025               
 ​                  
 ​                  |     ​ | ​ | ​    
 2024 
 ​    
 ​    |     ​ | ​ 
 ​ 
 ​ | ​      
 ​      
 Change 
 Amount 
 ​      
 ​      |    ​ 
    ​ | ​ 
 ​ |       ​ 
       ​ 
 Percent | ​ 
 ​ 
 ​ |
|:-----------------------------------------------------|:--|:-------------------|------:|:--|:-----|------:|:--|:-------|-----:|:--|--------:|:--|
| HCC                                                  | ​ | $                  |   437 | ​ | $    | 1,417 | ​ | $      | -980 |   |   -69.2