Company: ISRG
Filing Date: 2025-03-14
Form Type: DEF 14A
Source: 0001035267-25-000098
Chunk: 4

Company: INTUITIVE SURGICAL INC
Filing Date: 2025-03-14
Form: DEF 14A
Chunk 4
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 to enable better outcomes, improve operational efficiency, and leverage actionable insights, all of which can create new opportunities for clinical and economic value creation. It, and all other Intuitive products, are rigorously designed, tested, and validated to meet the highest patient safety standards. The Board of Directors is diligent in ensuring that these high standards are part of Intuitive’s culture and a key criteria for company success.

In further support of patient safety, we also continued the evolution of our Quality Management System (QMS) by further streamlining our management processes, enhancing our oversight tools, and empowering employees to be more effective and efficient. At the customer level, we continued to evolve and improve safety- and efficiency-related offerings, such as OnSite remote diagnostics, which enable real-time system evaluations and hourly proactive reviews to minimize service disruptions, and Genesis, a service that helps customers elevate their clinical and operational performance.

Aligned with our culture of continuous improvement, we continue to support rigorous, objective assessment of our products. A highlight among the 4,000 peer-reviewed articles published on Intuitive technologies in 2024 (more than 43,000 published to date), the Annals of Surgery published results from the COMPARE study (Comparing Perioperative Outcomes of Oncologic Minimally Invasive Laparoscopic, da Vinci Robotic, and Open Procedures) 1 . This meta

1 Ricciardi, Rocco MD, MPH*; Seshadri-Kreaden, Usha MSc†; Yankovsky, Ana MS†; Dahl, Douglas MD‡; Auchincloss, Hugh MD, MPH§; Patel, Neera M. MS†; Hebert, April E. PhD†; Wright, Valena MD ∥ . The COMPARE Study: Comparing Perioperative Outcomes of Oncologic Minimally Invasive Laparoscopic, Da Vinci Robotic, and Open Procedures: A Systematic Review and meta-analysis of The Evidence. Annals of Surgery ():10.1097/SLA.0000000000006572, October 22, 2024. | DOI: 10.1097/SLA.0000000000006572.

3

-analysis included 12 years of data across 22 countries and 230-peer-reviewed publications related to seven oncologic procedures performed using da Vinci robotic-assisted surgery, laparoscopic surgery, and open surgery. It demonstrated multiple benefits for da Vinci robotic-assisted surgery as compared to laparoscopy and open surgery, including