Company: SNY
Filing Date: 2025-10-27
Form Type: 424B5
Source: 0001193125-25-250786
Chunk: 32

Company: Sanofi
Filing Date: 2025-10-27
Form: 424B5
Chunk 32
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ed to the next day that is a business day and the Floating Rate Interest Payment Date will be such succeeding business day, and interest thereon will continue to accrue to but excluding such succeeding business day, except that if that
business day is in the next succeeding calendar month, the Floating Rate Interest Payment Date will be the immediately preceding business day and interest shall accrue to but excluding such preceding business day; provided further that the final
interest period for the Floating Rate Notes will be the period from and including the Floating Rate Interest Payment Date immediately preceding the maturity or redemption date, as applicable, of the Floating Rate Notes to, but excluding, the
maturity date or redemption date, as applicable. If the maturity date of the Floating Rate Notes or date of redemption or repayment falls on a day that is not a business day, the payment of interest and principal will be made on the next succeeding
business day, and no interest on such payment will accrue during the period from and after such original maturity date or date of redemption or repayment. Payments postponed to the next business day described above, as applicable, will be treated
under the Indenture as if they were made on the original due date, except for the continued accrual of interest and commencement of the following interest period as described above. Postponements of this kind, as applicable, will not result in a
default under the Notes or the Indenture.

The interest rate for any interest period will be Compounded SOFR, as determined on the
applicable date that is the second U.S. Government Securities Business Day (as defined below) immediately preceding the related Floating Rate Interest Payment Date or, in the case of redemption of the Floating Rate Notes, the date of redemption, as
applicable (the “Interest Determination Date”), plus a margin of %.

S-25

All payments of interest on the floating rate notes due on any Floating Rate Interest Payment Date will be made to the persons in whose names the floating rate notes are registered at the close of business on , , and , as applicable (which are the regular record dates), immediately preceding the related Floating Rate Interest Payment Date. However, interest that we pay on the maturity or redemption date, as applicable, will be payable to the person to whom the principal will be payable. Interest on the Floating Rate Notes will be calculated on the basis of a 360-dayyear and the actual number of calendar days in such interest period. Deutsche Bank Trust Company Americas, or its successor appointed by us, will act