Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 104

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 104
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, 2025, Comerica and its subsidiaries operated in five primary geographic markets—Texas, California,
Michigan, Arizona and Florida—and secondarily in several mountain, southeastern and other states, and in Canada and Mexico, and had 7,734 full-time and 335 part-time employees.

Comerica, one of the 25 largest U.S. commercial financial bank holding companies, focuses on building relationships and helping people and businesses be
successful. As of September 30, 2025, Comerica had approximately $77.4 billion in assets, $50.9 billion in loans, $62.6 billion in deposits and $7.4 billion in shareholders’ equity.

Comerica Holdings, a Delaware corporation, is a registered bank holding company that has elected to be a financial holding company under the BHC Act. Comerica
Holdings is a direct wholly owned subsidiary of Comerica. Comerica Holdings has no operating lines of business; rather, its primary purpose is to hold the stock of Comerica Bank & Trust.

Comerica’s common stock is traded on the NYSE under the symbol “CMA”, and Comerica depositary shares representing a 1/40th ownership
interest of Comerica preferred stock are currently listed on the NYSE under the symbol “CMA PrB.”

73

THE MERGERS

This section of the joint proxy statement/prospectus describes material aspects of the mergers. This summary may not contain all of the information that is important to you. You should carefully read this entire joint proxy statement/prospectus and the other documents we refer you to for a more complete understanding of the mergers. In addition, the description in this section incorporates by reference important business and financial information about each of Fifth Third and Comerica. You may obtain the information incorporated by reference into this document without charge by following the instructions in the section entitled “Where You Can Find More Information” beginning on page 179.

Terms of the Mergers

Each of Fifth Third’s and Comerica’s respective boards of directors has approved and adopted the merger agreement and the transactions contemplated
thereby, including the mergers. The merger agreement provides that, upon the terms and subject to the conditions set forth therein, Comerica will merge with and into Fifth Third Intermediary, which is referred to as the first merger, with Fifth
Third Intermediary continuing as the surviving corporation. Immediately thereafter, Comerica Holdings will merge with and