Company: CSTL
Filing Date: 2025-04-09
Form Type: DEF 14A
Source: 0001447362-25-000054
Chunk: 82

Company: CASTLE BIOSCIENCES INC
Filing Date: 2025-04-09
Form: DEF 14A
Chunk 82
---
 median compensated employee and calculating the pay ratio based on that employee’s annual total compensation allow companies to adopt a variety of methodologies, to apply certain exclusions, and to make reasonable estimates and assumptions that reflect their compensation practices, the pay ratio reported by other companies may not be comparable to the pay ratio reported above, as other companies may have different employment and compensation practices and may use different methodologies, exclusions, estimates and assumptions in calculating their own pay ratios.

#### Castle Biosciences 2025 Proxy Statement75
| Pay Versus Performance |

We are required by SEC rules to disclose certain information regarding compensation paid to our NEOs. The amounts set forth below under the headings “Compensation Actually Paid to PEO” and “Average Compensation Actually Paid to Non-PEO NEOs” have been calculated in a manner consistent with Item 402(v) of Regulation S-K. Footnote (2) below sets forth the adjustments from the Total Compensation for each NEO reported in the Summary Compensation Table for the relevant year.

|      |     | Summary Compensation Table Total for PEO ($)(1) |           |    | Compensation Actually Paid to PEO ($)(2) |            |    | Average Summary Compensation Table Total for Non-PEO NEOs ($)(1) |           |    | Average Compensation Actually Paid to Non-PEO NEOs ($)(2) |           |    |                      |     | Value of Initial Fixed $100 Investment Based on: |        |    |     |        |    |     |         |    |     |         |    |
| Year |     |                                                 |           |    | Total Shareholder Return ($)(3)          |            |    | Peer Group Total Shareholder Return ($)(3)                       |           |    | Net Income (Loss) ($)(4)                                  
 (in thousands)                                            |           |    | Total Revenue        
 ($)(5)(in thousands) |     |                                                  |        |    |     |        |    |     |         |    |     |         |    |
| (a)  |     |                                                 |           | -b |                                          |            | -c |                                                                  |           | -d |                                                           |           | -e |                      |     |                                                  |        | -f |     |        | -g |     |         | -h |     |         | -i |
| 2024 |     |                                                 | 6,941,074 |    |                                          |  9,967,499