Company: PSTV
Filing Date: 2025-06-20
Form Type: S-1/A
Source: 0001193125-25-142935
Chunk: 52

Company: PLUS THERAPEUTICS, INC.
Filing Date: 2025-06-20
Form: S-1/A
Chunk 52
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 thereunto duly authorized, in the City of Houston, State of Texas, on June 18, 2025.

| PLUS THERAPEUTICS, INC. |     |                                       |
| By:                     |     | /s/ Marc H. Hedrick                   |
|                         |     | Marc H. Hedrick, MD                   |
|                         |     | President and Chief Executive Officer |

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.

| Name                
 /s/ Marc H. Hedrick 
 Marc H. Hedrick, MD 
 /s/ Andrew Sims     
 Andrew Sims         |     | Title                                              
 President and Chief Executive Officer and Director 
 (Principal Executive Officer)                      
 Chief Financial Officer (Principal Financial       
 Officer and Principal Accounting Officer)          |     | Date          
 June 18, 2025 
 June 18, 2025 |
|:--------------------|:----|:---------------------------------------------------|:----|:--------------|
| * Richard J.        
 Hawkins             |     | Chairman of the Board                              |     | June 18, 2025 |
| * Howard            
 Clowes              |     | Director                                           |     | June 18, 2025 |
| * Kyle              
 Guse                |     | Director                                           |     | June 18, 2025 |

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| *By: |     | /s/ Marc H. Hedrick   |
|      |     | Marc H. Hedrick, M.D. |
|      |     | Attorney-in-fact      |

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