Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 12

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 12
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A copy of the merger agreement is attached as Annex Ato this joint proxy statement/prospectus. In this joint proxy statement/prospectus, we refer to the closing of the first merger as the “closing” and the date on which the closing occurs as the “closing date.” In order to complete the first merger, among other things,

| • |     | Fifth Third voting shareholders must vote to approve, voting together as a single class (such approval, the                                                                                                                                           
 “requisite Fifth Third vote”) the issuance of Fifth Third common stock in connection with the first merger of Comerica with and into Fifth Third Intermediary as merger consideration to holders of Comerica common stock pursuant to the             
 merger agreement (including for purposes of complying with NASDAQ Rule 5635(d), which requires approval of the issuance of shares of Fifth Third common stock in an amount that exceeds 20% of the currently outstanding shares of Fifth Third common 
 stock) (the “Fifth Third stock issuance,” and such proposal, the “Fifth Third stock issuance proposal”); and                                                                                                                                          |

| • |     | holders of Comerica common stock must vote to adopt (such adoption, the “requisite Comerica vote”) 
 the merger agreement (the “Comerica merger proposal”).                                             |

In addition, Fifth Third voting shareholders will also be asked to approve a proposal to adjourn the Fifth Third special meeting, if necessary or appropriate, to solicit additional proxies if, immediately prior to such adjournment, there are insufficient votes to approve the Fifth Third stock issuance proposal or to ensure that any supplement or amendment to this joint proxy statement/prospectus is timely provided to Fifth Third voting shareholders (the “Fifth Third adjournment proposal”). Holders of Fifth Third preferred stock and Fifth Third depositary shares representing Fifth Third preferred stock (other than Fifth Third voting preferred stock) are not entitled to, and are not requested to, vote at the Fifth Third special meeting. Fifth Third voting shareholders are not entitled to appraisal or dissenters’ rights in connection with the transactions contemplated by the merger agreement under Chapter 1701 of Title 17 of the Ohio Revised Code (the “OGCL”). For more information, see the section entitled “ The Mergers — Appraisal or Dissenters’ Rights in the First Merger” beginning on page 118. Comerica stockholders will also be asked (i) to approve, on an advisory (non-binding)basis, the merger-related compensation payments that will or