Company: SMNR
Filing Date: 2025-08-11
Form Type: S-4/A
Source: 0001193125-25-177416
Chunk: 2

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-08-11
Form: S-4/A
Chunk 2
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 “Semnur Pharmaceuticals, Inc.”                                                                                                                                                     |

The Registrant hereby amends this registration statement on such date or dates as may be necessary to delay its effective date until the Registrant shall file a further amendment which specifically states that this registration statement shall thereafter become effective in accordance with Section 8(a) of the Securities Act of 1933, as amended, or until the registration statement shall become effective on such date as the Securities and Exchange Commission, acting pursuant to said Section 8(a), may determine.

TABLE OF CO-REGISTRANTS

| Exact Name of Co-Registrant       
 as Specified in its Charter(1)(2) |     | State or Other   
 Jurisdiction of  
 Incorporation or 
 Organization     |          |     | Primary        
 Standard       
 Industrial     
 Classification 
 Code Number    |      |     | I.R.S. Employer       
 Identification Number |            |
| Semnur Pharmaceuticals, Inc.      |     |                  | Delaware |     |                | 2836 |     |                       | 46-2968523 |

(1) The Co-Registranthas the following principal executive office: Semnur Pharmaceuticals, Inc. 960 San Antonio Road Palo Alto, CA 94303 (2) The agent for service for the Co-Registrantis: Jaisim Shah Chief Executive Officer and President Semnur Pharmaceuticals, Inc. 960 San Antonio Road Palo Alto, CA 94303 (650) 516-4310

EXPLANATORY NOTE

This Amendment No.6 (“Amendment No. 6”) to the Registration Statement on Form S-4 (File No. 333-283019) of Denali Capital Acquisition Corp. (the “Registration Statement”) is being filed as an exhibits-only filing to amend Exhibit 107 in Part II of this Amendment No. 6. This
Amendment No. 6 does not modify any provision of the proxy statement/prospectus that forms a part of the Registration Statement. Accordingly, this Amendment No. 6 consists only of the cover page, this explanatory note, Item 21 of Part II
of the Registration Statement, the signature pages to the Registration Statement, and the filed exhibit.

PART II INFORMATION NOT REQUIRED IN THE PROSPECTUS Item 21. Exhibits and Financial Statements Schedules

| Exhibit 
 Number  
 1.1     
 2.1#‡   |     | Description                                                                                                                                                                                                                     
 Underwriting Agreement, dated as of April 6, 2022, by