Company: WSBC
Filing Date: 2025-09-11
Form Type: 424B5
Source: 0001193125-25-201360
Chunk: 44

Company: WESBANCO INC
Filing Date: 2025-09-11
Form: 424B5
Chunk 44
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 directors shall automatically be reduced accordingly. Any Preferred Stock Director may be removed at any time without cause by the holders of record of a majority of the outstanding shares of Series B Preferred Stock when they have the voting rights described above (voting together as a class with all series of voting preferred stock then outstanding). So long as a Nonpayment Event shall continue, any vacancy in the office of a Preferred Stock Director (other than prior to the initial election after a Nonpayment Event) may be filled by the written consent of the Preferred Stock Director remaining in office, or if none remains in office, by a vote of the holders of record of a majority of the outstanding shares of Series B Preferred Stock and all voting preferred stock when they have the voting rights described above (voting together as a class). The Preferred Stock Directors shall each be entitled to one vote per director on any matter that shall come before the Board of Directors for a vote. So long as any shares of Series B Preferred Stock remain outstanding, we will not, without the affirmative vote or consent of the holders of at least two-thirdsof the outstanding shares of the Series B Preferred Stock and all other series of voting preferred stock at the time outstanding and entitled to vote thereon, including the Series A Preferred Stock, voting together as a single class:

| • |     | amend or alter the provisions of our Charter or Articles of Amendment so as to authorize or create, or increase                                                                                           
 the authorized amount of, any class or series of stock ranking senior to the Series B Preferred Stock with respect to payment of dividends or the distribution of assets upon liquidation, dissolution or 
 winding-up of Wesbanco;                                                                                                                                                                                   |

S-31

| • |     | amend, alter or repeal the provisions of our Charter or Articles of Amendment so as to materially and adversely            
 affect the special rights, preferences, privileges and voting powers of the Series B Preferred Stock, taken as a whole; or |

| • |     | consummate a binding share exchange or reclassification involving the Series B Preferred Stock or a merger or                                                                                                                                            
 consolidation of Wesbanco with another corporation or other entity, unless in each case (i) the shares of Series B Preferred Stock remain outstanding or, in the case of any such merger or consolidation with respect to which we are not the           
 surviving or resulting entity, are converted into or exchanged for preferred securities of the surviving or resulting entity or its ultimate parent, and (ii) such shares remaining outstanding or such preferred securities, as the case may be,        
 have such