Company: SCLXW
Filing Date: 2025-12-29
Form Type: 424B3
Source: 0001193125-25-335429
Chunk: 477

Company: Scilex Holding Co
Filing Date: 2025-12-29
Form: 424B3
Chunk 477
---
5 Warrant Holders exercised in full their respective December 2024 RDO Common
Warrants originally issued to the September 2025 Warrant Holders pursuant to the December 2024 RDO Purchase Agreement for an aggregate of 179,236 shares of Common Stock and deferred, for a deferral fee of $7.72 per share being exercised, their right
to receive an amortization payment scheduled to be paid by the Company on October 1, 2025 as set forth in the amortization schedule included in Tranche B Note issued to, among others, each September 2025 Warrant Holder in exchange for the
Company’s agreement to issue the September 2025 Warrants. As of the date of this prospectus, there are 275,000 September 2025 Warrants that remain outstanding.

The September 2025 Warrants are exercisable immediately from the date of issuance and expire on December 13, 2029. The exercise price of
the September 2025 Warrants of $20.00 per share is subject to adjustment for any stock split, stock dividend, stock combination, recapitalization or similar event, and is also subject to full-ratchet adjustment in connection with a subsequent
offering at a per share price less than the exercise price then in effect.

A holder shall not have the right to exercise any portion of a
September 2025 Warrant to the extent that, after giving effect to such exercise, the holder (together with certain related parties) would beneficially own in excess of 4.99% of shares of Common Stock outstanding immediately after giving effect to
such exercise. Such maximum percentage may be raised or lowered to any other percentage not in excess of 9.99%, at the option of the holder, except that any increase will only be effective upon 61 days’ prior notice to the Company.

The foregoing summaries of the terms and conditions of the September 2025 Warrants do not purport to be complete and are qualified in their
entirety by reference to the copies of the form of September 2025 Warrant that is filed as an exhibit to the registration statement of which this prospectus forms a part. See the section titled “Description of September 2025 Warrants” for more detailed information about the September 2025 Warrants.

November 2025 Warrants

On November 23, 2025, we entered into the Warrant Inducement Agreement with the Exercising Investor. Pursuant to