Company: BFRG
Filing Date: 2025-04-25
Form Type: 424B5
Source: 0001641172-25-006297
Chunk: 1

Company: BullFrog AI Holdings, Inc.
Filing Date: 2025-04-25
Form: 424B5
Chunk 1
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 under this prospectus supplement will be made in sales deemed to be “at the market offerings” as defined in Rule 415 promulgated under the Securities Act of 1933, as amended, or the Securities Act. The sales agent is not required to sell any specific amount of securities, but will act as our sales agent using commercially reasonable efforts consistent with its normal trading and sales practices, on mutually agreed terms between the sales agent and us. There is no arrangement for funds to be received in any escrow, trust or similar arrangement.

The sales agent will be entitled to compensation at a commission rate equal to 3.0% of the aggregate gross sales price per share of common stock issued by us and sold under the Sales Agreement. In connection with the sale of the common stock on our behalf, the sales agent will be deemed to be an “underwriter” within the meaning of the Securities Act and the compensation of the sales agent will be deemed to be underwriting commissions or discounts. We have also agreed to provide indemnification and contribution to the sales agent with respect to certain liabilities, including liabilities under the Securities Act or the Securities Exchange Act of 1934, as amended.

Our business and an investment in our common stock involve significant risks. These risks are described under the caption “ Risk Factors” beginning on page S-6 of this prospectus supplement and in the documents incorporated by reference into this prospectus supplement.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the accuracy or adequacy of this prospectus supplement. Any representation to the contrary is a criminal offense.

<div align='center'>BTIG

The date of this prospectus supplement is , 2025.</div>

<div align='center'>Table of Contents</div>

|                                                 |     | Page |
| ABOUT                                           
 THIS PROSPECTUS SUPPLEMENT                      |     | S-1  |
| CAUTIONARY                                      
 NOTE REGARDING FORWARD-LOOKING STATEMENTS       |     | S-2  |
| PROSPECTUS                                      
 SUPPLEMENT SUMMARY                              |     | S-3  |
| RISK                                            
 FACTORS                                         |     | S-6  |
| CERTAIN                                         
 MATERIAL U.S. FEDERAL INCOME TAX CONSIDERATIONS |     | S-9  |
| USE                                             
 OF PROCEEDS                                     |     | S-14 |
| DILUTION                                        |     | S-15 |
| PLAN                                            
 OF DISTRIBUTION                                 |