Company: BDRX
Filing Date: 2025-11-24
Form Type: 424B3
Source: 0001214659-25-017136
Chunk: 1

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-11-24
Form: 424B3
Chunk 1
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 carefully consider before deciding to purchase these securities.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

<div align='center'>___________________________________

The date of this prospectus is November 21, 2025</div>

<div align='center'>TABLE OF CONTENTS</div>

|                                                         | Page |
| ABOUT THIS PROSPECTUS                                   |    1 |
| PRESENTATION OF FINANCIAL AND OTHER INFORMATION         |    2 |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS    |    4 |
| PROSPECTUS SUMMARY                                      |    5 |
| RISK FACTORS                                            |    9 |
| USE OF PROCEEDS                                         |   10 |
| DIVIDEND POLICY                                         |   11 |
| CAPITALIZATION                                          |   12 |
| SELLING SHAREHOLDERS                                    |   13 |
| DESCRIPTION OF OFFERED SECURITIES AND OUR SHARE CAPITAL |   17 |
| DESCRIPTION OF AMERICAN DEPOSITARY SHARES               |   36 |
| PLAN OF DISTRIBUTION                                    |   50 |
| LEGAL MATTERS                                           |   51 |
| EXPERTS                                                 |   51 |
| WHERE YOU CAN FIND MORE INFORMATION                     |   51 |
| INCORPORATION OF CERTAIN INFORMATION BY REFERENCE       |   51 |
| ENFORCEMENT OF CIVIL LIABILITIES                        |   52 |
| EXPENSES OF THE OFFERING                                |   52 |

| i |

<div align='center'>ABOUT THIS PROSPECTUS</div>

This prospectus is part of a registration
statement that we filed with the Securities and Exchange Commission, or SEC. As permitted by the rules and regulations of the SEC, the
registration statement filed by us includes additional information not contained in this prospectus. You may read the registration statement
and the other reports we file with the SEC at the SEC’s website or its offices described below under the heading “Where You
Can Find More Information”.

You should rely only on the information
contained in this prospectus. We have not authorized any person to provide you with information different from that contained in this
prospectus. This prospectus is not an offer to sell, nor is it seeking an offer to buy, these securities in any state where the offer
or sale is not permitted.