Company: SHPH
Filing Date: 2025-01-24
Form Type: 424B3
Source: 0001493152-25-003508
Chunk: 52

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-01-24
Form: 424B3
Chunk 52
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 be subject to fines, injunctions or the imposition of civil or criminal penalties;                                                 |

| ● | regulatory                                                                                                          
 authorities may require the addition of labeling statements, such as a “black box” warning or a contraindication;   |
| ● | we                                                                                                                  
 may be required to create a Medication Guide outlining the risks of such side effects for distribution to patients; |

| 36 |

| ● | we                                                         
 could be sued and held liable for harm caused to patients; |
| ● | the                                                        
 product may become less competitive; and                   |
| ● | our                                                        
 reputation.                                                |

Risks Related to our Common Stock

While our Company’s management is working to improve our internal controls and procedures, at present management has determined that our internal controls were deemed to be inadequate, which could cause our financial reporting to be unreliable and lead to misinformation being disseminated to the public.

Our management is responsible for establishing and maintaining adequate internal control over financial reporting. As defined in Rule 13a-15(f) under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), internal control over financial reporting is a process designed by, or under the supervision of, the principal executive and principal financial officer and effected by the board of directors, management and other personnel, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles and includes those policies and procedures that:

| ● | pertain                                                                                                                                
 to the maintenance of records that in reasonable detail accurately and fairly reflect the transactions and dispositions of our assets; |

| ● | provide                                                                                                                            
 reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with  
 generally accepted accounting principles, and that receipts and expenditures of the Company are being made only in accordance with 
 authorizations of management and/or directors of the Company; and                                                                  |
| ● | provide                                                                                                                            
 reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use or disposition of the Company’s     
 assets that could have a material effect on the financial statements.                                                              |

We are required to include a report of management on the effectiveness of our internal control over financial reporting. We expect to incur additional expenses and diversion of management’s time as a result of performing the system and process evaluation, testing and remediation required in order to comply with the management certification requirements.

Presently, we do not have a sufficient number of employees to segregate responsibilities and may be unable to afford increasing