Company: SCLXW
Filing Date: 2025-12-12
Form Type: 424B3
Source: 0001193125-25-317683
Chunk: 5

Company: Scilex Holding Co
Filing Date: 2025-12-12
Form: 424B3
Chunk 5
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or as the Lender may otherwise direct) of such number of Listco Securities as is set forth in any Funding Notification delivered to the Borrower as provided in Section 2.2(b) below (such Listco Securities so Delivered, together with all substitutions, additions and proceeds thereof, all dividends, interest, income, revenue, return of capital or other distributions made in respect thereof and all rights and claims of the Borrower in respect of the foregoing or evidenced thereby being, collectively, the“Pledged Securities”).

Continuance of Loan Agreement. Except as amended hereby, the Loan Agreement shall continue in full force and effect unamended, in accordance with its terms, as modified by the terms of this Amendment.

Governing Law. This Amendment shall be interpreted, construed and enforced according to the laws of Bermuda .

- 2 - 5. Independent Legal Advice. The Borrower acknowledges that: (i) the Lender has recommended and encouraged the Borrower to obtain independent legal advice with respect to this Amendment and the transactions contemplated hereby; (ii) it has, in fact, been given an opportunity to obtain independent legal advice from counsel/advisors of its choosing; and (iii) if it has not obtained independent legal advice, despite having been encouraged and given the opportunity to do so, the Borrower explicitly waives the right to obtain such advice, and, in any event, the Borrower acknowledges that it has read and understood this Amendment, that it is signing this Amendment and the schedule freely and voluntarily and without duress or undue influence of any nature whatsoever. 6. Counterparts. This Amendment may be: (i) executed in two or more counterparts, each of which counterparts when so executed and delivered shall be deemed to be an original, but all of which counterparts together shall constitute one and the same document; and/or (ii) transmitted by facsimile and/or internet device and that the reproduction of signatures by way of facsimile and/or PDF device will be treated as though such reproductions were executed originals and communication by such means will be legal and binding. IN WITNESS WHEREOF, the parties have executed this Amendment as of the date first above written.

| THE ST. JAMES BANK & TRUST COMPANY LTD. |                   |                |
| Per:                                    | /s/ Bernard Kemp  |                |
|                                         | Name:             | Bernard Kemp   |
|                                         | Title:            | President      |
| Per:                                    | /s/ Dion Thompson |