Company: TAK
Filing Date: 2025-06-25
Form Type: F-3ASR
Source: 0001395064-25-000097
Chunk: 0

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-06-25
Form: F-3ASR
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission on June 25, 2025</div>

#### Registration No. 333-____

### UNITED STATES

### SECURITIES AND EXCHANGE COMMISSION

#### Washington, D.C. 20549

#### FORM F-3

### REGISTRATION STATEMENT

#### UNDER

#### THE SECURITIES ACT OF 1933
| Takeda Yakuhin Kogyo Kabushiki Kaisha           |     | Takeda U.S. Financing, Inc.  |
| (Exact name of Registrant as                    
 specified in its charter)                       |     | -Exact name of Registrant as 
 specified in its charter     |
| Takeda Pharmaceutical Company Limited           |     |                              |
| (Translation of Registrant’s Name into English) |     |                              |

| Japan                                     |     | Delaware                                 |
| (State or Other Jurisdiction of           
 Incorporation or Organization)            |     | -State or Other Jurisdiction of          
 Incorporation or Organization            |
| None                                      |     | 33-1784620                               |
| (I.R.S. Employer Identification Number)   |     | -I.R.S. Employer Identification Number   |
| 1-1, Nihonbashi Honcho 2-chome            
 Chuo-ku, Tokyo 103-8668, Japan            |     | 500 Kendall Street                       
 Cambridge, Massachusetts 02142           |
| 81-3-3278-2306                            |     | 1-857-757-6000                           |
| (Address and Telephone Number of          
 Registrant’s Principal Executive Offices) |     | -Address and Telephone Number of         
 Registrant’s Principal Executive Offices |

<div align='center'>Takeda Pharmaceuticals U.S.A., Inc., 500 Kendall Street, Cambridge, MA 02142 U.S.A.

(1-857-757-6000)

(Name, Address and Telephone Number of Agent for Service for Takeda Pharmaceutical Company Limited)</div>

<div align='center'>Copies To:</div>

| Keiji Hatano                      
 Nirav N. Mehta                    
 Sullivan & Cromwell LLP           
 Otemachi First Square             
 5-1, Otemachi 1-chome             
 Chiyoda-ku, Tokyo 100-0004, Japan 
 +81-3-3123-6140                   |     | David C. Snowden                  
 Simpson Thacher & Bartlett LLP    
 Ark