Company: LIMN
Filing Date: 2025-01-16
Form Type: POS AM
Source: 0001104659-25-003835
Chunk: 670

Company: Liminatus Pharma, Inc.
Filing Date: 2025-01-16
Form: POS AM
Chunk 670
---
 and Treasurer

<div align='center'>Signature Page to Amendment to Business Combination Agreement

A-79</div>

TABLE OF CONTENTS

### THIRD AMENDMENT TO BUSINESS COMBINATION AGREEMENT
This Third Amendment to Business Combination Agreement (this “

#### Amendment
”) is entered into as of March 9, 2024, by and among Iris Acquisition Corp, a Delaware corporation (the “

#### SPAC
”), Iris Parent Holding Corp., a Delaware corporation (“

#### ParentCo
”), and Liminatus Pharma, LLC, a Delaware limited liability company (the “

#### Company
”). Each of SPAC, ParentCo, and the Company is also referred to herein as a “

#### Party
” and, collectively, the “

#### Parties
”.

### RECITALS
WHEREAS, the Parties, along with Liminatus Pharma Merger Sub, Inc., a Delaware corporation, and SPAC Merger Sub, Inc., a Delaware corporation, entered into that certain Business Combination Agreement, dated November 30, 2022 (the “

#### BCA
”);

WHEREAS, the Parties previously entered into that certain Amendment to Business Combination Agreement, dated June 1, 2023, to, among other things, extend the Outside Date (as defined in the BCA) to September 11, 2023;

WHEREAS, the Parties previously entered into that certain Second Amendment to Business Combination Agreement, dated August 14, 2023, to among other things, extend the Outside Date (as defined in the BCA) to March 9, 2024;

WHEREAS, the Parties desire to further amend the BCA to extend the Outside Date; and WHEREAS, Section 11.1 of the BCA provides that the BCA may only be amended by a written instrument executed by SPAC, ParentCo, and the Company.

### AGREEMENT
NOW, THEREFORE, in consideration of the premises and the mutual covenants and agreements contained herein and in the BCA, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties hereto do hereby agree as follows:

1. Definitions . Capitalized terms used herein but not otherwise defined shall have the meanings given to them in the BCA.

2.

Amendment to BCA .

(a) Section 10.1(c) . Section 10.1(c) of the BCA is hereby amended and restated in its entirety to read as follows:

“by