Company: ARVN
Filing Date: 2025-02-11
Form Type: S-8
Source: 0001655759-25-000017
Chunk: 0

Company: ARVINAS, INC.
Filing Date: 2025-02-11
Form: S-8
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission on February 11, 2025</div>

#### Registration No. 333-

### UNITED STATES

### SECURITIES AND EXCHANGE COMMISSION

#### WASHINGTON, DC 20549
<div align='center'>__________________</div>

#### FORM S-8

### REGISTRATION STATEMENT

#### UNDER

#### THE SECURITIES ACT OF 1933
<div align='center'>__________________</div>

#### ARVINAS, INC.
<div align='center'>(Exact Name of Registrant as Specified in Its Charter)

__________________</div>

| Delaware                                 |     |         47-2566120 |
| (State or Other Jurisdiction of          
 Incorporation or Organization)           |     |   -I.R.S. Employer 
 Identification No. |
| 5 Science Park                           
 395 Winchester Ave.                      
 New Haven, Connecticut                   |     |              06511 |
| (Address of Principal Executive Offices) |     |          -Zip Code |

#### 2018 Stock Incentive Plan

#### 2018 Employee Stock Purchase Plan
<div align='center'>(Full Title of the Plans)</div>

#### John Houston, Ph.D.

#### President and Chief Executive Officer

#### Arvinas, Inc.

#### 5 Science Park

#### 395 Winchester Ave.

#### New Haven, Connecticut 06511
<div align='center'>(Name and Address of Agent for Service)

(203) 535-1456

(Telephone Number, Including Area Code, of Agent for Service)

__________________</div>

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

| Large accelerated filer |     | ☒ |     | Accelerated filer         |     | ☐ |
| Non-accelerated filer   |     | ☐ |     | Smaller reporting company |     | ☐ |
|                         |     |   |     | Emerging growth company   |     | ☐ |

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new