Company: RGNX
Filing Date: 2025-06-13
Form Type: S-3
Source: 0001193125-25-140870
Chunk: 14

Company: REGENXBIO Inc.
Filing Date: 2025-06-13
Form: S-3
Chunk 14
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 fiduciary duty as directors, except for liability that cannot be eliminated under the Delaware General Corporation Law. Accordingly, our directors will not be personally liable for monetary damages for breach of their fiduciary duty as directors, except for liabilities:

| • |     | for any breach of the director’s duty of loyalty to us or our stockholders; |

| • |     | for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law; |

| • |     | for unlawful payments of dividends or unlawful stock repurchases or redemptions, as provided under 
 Section 174 of the Delaware General Corporation Law; or                                            |

| • |     | for any transaction from which the director derived an improper personal benefit. |

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Any amendment or repeal of these provisions will require the approval of the holders of
shares representing at least two-thirds of the shares entitled to vote in the election of directors, voting as one class.

Our restated certificate of incorporation and amended and restated bylaws also provide that we will indemnify our directors and officers to
the fullest extent permitted by Delaware law. Our amended and restated bylaws also permit us to purchase insurance on behalf of any officer, director, employee or other agent for any liability arising out of his or her actions as our officer,
director, employee or agent, regardless of whether Delaware law would permit indemnification. We have entered into separate indemnification agreements with our directors and officers that require us, among other things, to indemnify them against
certain liabilities that may arise by reason of their status or service as directors and to advance their expenses incurred as a result of any proceeding against them as to which they could be indemnified. We believe that the limitation of liability
provision in our restated certificate of incorporation and the indemnification agreements facilitate our ability to continue to attract and retain qualified individuals to serve as directors and officers. The limitation of liability and
indemnification provisions in our restated certificate of incorporation and amended and restated bylaws may discourage stockholders from bringing a lawsuit against directors for breach of their fiduciary duties. They may also reduce the likelihood
of derivative litigation against directors and officers, even though an action, if successful, might benefit us and our stockholders. A stockholder’s investment may be harmed to the extent we pay the costs of settlement and damage awards
against directors and officers pursuant to these indemnification provisions.

Stock Exchange Listing

Our common stock is listed on The Nasdaq Global Select Market