Company: PSTV
Filing Date: 2025-06-18
Form Type: S-1
Source: 0001193125-25-142215
Chunk: 2

Company: PLUS THERAPEUTICS, INC.
Filing Date: 2025-06-18
Form: S-1
Chunk 2
---
 our common stock by the selling stockholder. However, we may receive up to $50 million aggregate gross proceeds from sales of common stock to
Lincoln Park under the Purchase Agreement. Pursuant to the Purchase Agreement, we agreed to pay an aggregate amount of $500,000 (which we refer to in this prospectus as the Initial Commitment Fee) in cash, shares of our common stock (which shares we
refer to in this prospectus as the Initial Commitment Shares) or any combination thereof to Lincoln Park as consideration for its irrevocable commitment to purchase shares of our common stock at our direction under the Purchase Agreement. We have
also agreed to pay an additional commitment fee (the “Additional Commitment Fee”), which we may elect to pay in cash, shares of our common stock or any combination thereof, upon our receipt of $25 million aggregate gross proceeds from
sales of common stock to Lincoln Park under the Purchase Agreement. See “The Lincoln Park Transaction” for a description of the Purchase Agreement and “Selling Stockholder” for additional information regarding Lincoln Park.

The selling stockholder may sell or otherwise dispose of the shares of common stock described in this prospectus in a number of different ways
and at varying prices. See “Plan of Distribution” for more information about how the selling stockholder may sell or otherwise dispose of the common stock being registered pursuant to this prospectus. The selling stockholder is an
“underwriter” within the meaning of Section 2(a)(11) of the Securities Act of 1933, as amended (the “Securities Act”).

The selling stockholder will pay all brokerage fees and commissions and similar expenses in connection with any resale or disposition of the
shares of common stock described in this prospectus by the selling stockholder. We will pay the expenses incurred in registering under the Securities Act the offer and sale of the shares of common stock to which this prospectus relates by the
selling stockholder, including legal and accounting fees. See “Plan of Distribution”.

Our common stock is currently listed on
the Nasdaq Capital Market (“Nasdaq”) under the symbol “PSTV”. On June 16, 2025, the closing price of our common stock, as reported on Nasdaq, was $0.31 per share.

Investing in our securities involves a high degree of risk. These risks are described in the “ Risk Factors” section on page 3 of this prospectus. You should also consider the risk factors described or referred to in any