Company: SHPH
Filing Date: 2025-02-27
Form Type: 424B3
Source: 0001493152-25-008476
Chunk: 88

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-02-27
Form: 424B3
Chunk 88
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   (345,000 
   (334,444 
          — 
  2,570,083 
 (5,840,787 
  8,417,203 
  2,576,416 | ) 
 ) 
 ) 
 ) 
 ) 
 ) 
 ) 
 ) 
 ) 
 ) 
 ) 
 ) 
 ) 
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|:------------------------------------------------------------------------------------------------------------------|:----|:-------------|-----------:|:--|:----|:-----|-----------:|:--|
| Interest                                                                                                          |     | $            |     86,589 |   |     | $    |    164,807 |   |
| Income taxes                                                                                                      |     | $            |          — |   |     | $    |          — |   |
| Supplemental non-cash financing activities:                                                                       |     |              |            |   |     |      |            |   |
| Common stock issued for settlement of debt                                                                        |     | $            |  1,947,294 |   |     | $    |  2,697,849 |   |
| Warrants issued for financing fees, net of issuance fees of $0 and $8,727, respectively                           |     | $            |          — |   |     | $    |     90,816 |   |
| Initial recognition of right of use asset and liability                                                           |     | $            |          — |   |     | $    |    365,556 |   |

<div align='center'>The accompanying notes are an integral part of these consolidated financial statements.</div>

| F-5 |

Note 1 – Organization and Liquidity

Organization and Line of Business

Shuttle Pharmaceuticals Holdings, Inc. (“we,” “us,” “our,” or the “Company”) was originally formed as Shuttle Pharmaceuticals, LLC in the State of Maryland on December 18, 2012. On August 12, 2016, the Company filed articles of conversion with the State of Maryland to convert from an LLC to a C corporation, at which time the Company changed its name to Shuttle Pharmaceuticals, Inc. (“Shuttle”). In connection with the conversion the Company issued 5,625,000 shares of common stock in exchange for 100% of the outstanding membership interests in Shuttle prior to conversion. On June 4, 2018, Shuttle completed a reverse merger with Shuttle Pharmaceuticals Holdings, Inc. (then known as Shuttle Pharma Acquisition Corp, Inc.), a Delaware