Company: WSBC
Filing Date: 2025-02-10
Form Type: 425
Source: 0000950170-25-017126
Chunk: 2

Company: WESBANCO INC
Filing Date: 2025-02-10
Form: 425
Chunk 2
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 FILED WITH THE SEC, AS WELL AS ANY AMENDMENTS OR SUPPLEMENTS TO THOSE DOCUMENTS, BECAUSE THEY CONTAIN IMPORTANT INFORMATION.The Registration Statement on Form S-4, which includes the joint proxy statements/prospectus, and other related documents filed by the Company or Premier with the SEC, may be obtained for free at the SEC’s website atwww.sec.gov, and from either the Company’s or Premier Financial’s website atwww.wesbanco.comorwww.premierfincorp.com, respectively.

No Offer or Solicitation

This Current Report on Form 8-K shall not constitute an offer to sell or a solicitation of an offer to buy any securities nor shall there be any sale of securities in any state or jurisdiction in which such offer, solicitation, or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

Item 9.01 Financial Statements and Exhibits.

(d)Exhibits:

99.1 Presentation on fourth quarter 2024 results by Wesbanco, Inc., at various investor conferences or other events in the first quarter of 2025.

104 Cover Page Interactive Data File (embedded within the Inline XBRL document).

<div align='center'>SIGNATURE</div>

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

| Date: | February 10, 2025 | By: | Wesbanco, Inc.                      
 (registrant)                        
 /s/ Daniel K. Weiss, Jr.            |
|:------|:------------------|:----|:------------------------------------|
|       |                   |     | Daniel K. Weiss, Jr.                
 Senior Executive Vice President and 
 Chief Financial Officer             |

Exhibit 99.1

Investor Presentation(Q1 2025)(WSBC financials as of the three months ended December 31, 2024) John Iannone Senior Vice President, Investor Relations 304-905-7021 ©2025 WesBanco, Inc. | All rights reserved

Forward-looking statements in this report relating to WesBanco’s plans, strategies, objectives, expectations, intentions and adequacy of resources, are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The information contained in this report should be read in conjunction with WesBanco’s Form 10-K for