Company: INSP
Filing Date: 2025-03-18
Form Type: DEF 14A
Source: 0001140361-25-009249
Chunk: 4

Company: Inspire Medical Systems, Inc.
Filing Date: 2025-03-18
Form: DEF 14A
Chunk 4
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 (the “Company,” “Inspire,” “we,” “us,” or “our”), in connection with our Annual Meeting. This Notice of Annual Meeting and Proxy Statement are first being distributed or made available, as the case may be, on or about March 18, 2025. In connection with our solicitation of proxies for our 2026 annual meeting of stockholders, we intend to file a proxy statement and WHITE proxy card with the Securities and Exchange Commission (the “SEC”). Stockholders may obtain our proxy statement (and any amendments and supplements thereto) and other documents as and when filed with the SEC without charge from the SEC’s website at: www.sec.gov.

| Inspire Medical Systems, Inc. |     | 2 |     | 2025 Proxy Statement |

TABLE OF CONTENTS

About Inspire Inspire Medical Systems, Inc. is a medical technology focused on the development and commercialization of innovative, minimally invasive solutions for patients with OSA. Our proprietary Inspire system is the first and only FDA, European Medical Device Regulation (“EU MDR”), and Japan Pharmaceuticals and Medical Devices Agency-approved neurostimulation technology of its kind that provides a safe and effective treatment for patients with moderate to severe OSA. Our Mission: We are committed to enhancing patients’ lives through sleep innovation. We are steadfast in our commitment to prioritize patient outcomes, act with integrity and lead with respect. With positive persistence at our core, we are committed to all those we serve. Core Values : Our core values, reflected below, guide our business decisions and define who we are. Inspire is safe with a strong track record of positive clinical outcomes

| How does Inspire compare against your previous experience with CPAP? |     | 91% |     | Say Inspire is better1       |
| I would recommend Inspire to a friend or family member.              |     | 93% |     | Agree or strongly agree1     |
| Given the chance, I would choose to receive Inspire again.           |     | 92% |     | Agree or strongly agree1     |
| Overall, how satisfied are you with Inspire?                         |     | 90% |     | Satisfied or very satisfied1 |

| 1 | Data on file. |

| Inspire Medical Systems, Inc. |     | 3 |     | 2025 Proxy Statement |

TABLE OF CONTENTS

| ABOUT INSPIRE |

2024 Business Highlights

| • |     | Generated revenue of $