Company: QTIWW
Filing Date: 2025-01-16
Form Type: S-1
Source: 0001628280-25-001723
Chunk: 214

Company: QT IMAGING HOLDINGS, INC.
Filing Date: 2025-01-16
Form: S-1
Chunk 214
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 the breast and extremity scanners, and uses the Company’s Open Partial Angle Scanner concept.

22 See , National Library of Medicine, Problems and Preferences in Pediatric Imaging (Oct. 2015), available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693383/.

23 WHO, Ionizing Radiation, Health Effects and Protective Measures (Apr. 29, 2016), available at https://www.who.int/news-room/fact-sheets/detail/ionizing-radiation-health-effects-and-protective-measures.

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The Open Partial Angle Scanner will be applied to infant body imaging in the proposed QT Infant Scanner (concept drawing)

Image 19

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Clinical Images

The Company has not imaged infants but has demonstrated its ability to image the body through imaging of neonatal pigs. Comparative images for QTscan vs MRI are shown below for a neonatal pig (Image 20). Note the higher contrast and more detail in the QTscan (left).

| Whole Body QTscan |     | Whole Body MRI Scan |

<div align='center'>Newborn piglet whole body imaging using the Company’s technology.

Image 20</div>

Other anatomic detail in the newborn pig’s heart and lungs are shown in Images 21, 22, 23 and 24 using the Company’s technology.

<div align='center'>Image 21 (left), Image 22 (center) and Image 23 (right)

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Piglet Lung Imaging

Image 24</div>

The Company has done partial-angle image reconstruction internal studies comparing the image quality of 325-degree rotation (open angle) to 360-degree (full rotation) reconstructions of a piglet’s pelvis (Image 25). We believe the image quality is maintained in the partial-angle reconstruction.

<div align='center'>All views (left) vs partial angle reconstruction (right) of the piglet pelvis

Image 25

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#### The Company’s Image Guided Procedures
The Need: In addition to using the Open Partial Angle Scanner as the proposed QT Infant Scanner, it can also be used for a variety of other image guided procedures including:

• Breast biopsy of small lesions (<5mm)

• Orthopedic biopsy of bones, joints, muscle or connective tissues

• Orthopedic injections

• Stem cell injections

• Soft tissue ablation

• Real-time non-radiation imaging of vascular procedures

• Angiography without radiation

• Cryoab