Company: SMNR
Filing Date: 2025-08-13
Form Type: 424B3
Source: 0001193125-25-179226
Chunk: 836

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-08-13
Form: 424B3
Chunk 836
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 its sole stockholder and recommended the approval and
adoption of this Agreement by its sole stockholder; and

WHEREAS, at the Closing, Parent, certain shareholders of Parent and Scilex (in
its capacity as a Stockholder) will enter into an Amended and Restated Registration Rights Agreement with Parent (the “”) in the form attached hereto as (with such
changes as may be agreed in writing by Parent and the Company), which will, among other things, govern the registration of certain Domesticated Parent Common Shares for resale and also govern restrictions on transfer of certain Domesticated Parent
Common Shares and which shall be effective as of the Closing.

NOW, THEREFORE, in consideration of the premises set forth above,
which are incorporated in this Agreement as if fully set forth below, and the representations, warranties, covenants and agreements contained in this Agreement, and intending to be legally bound hereby, the parties accordingly agree as follows:

ARTICLE I

DEFINITIONS

The terms
defined in the preamble shall have the respective meanings ascribed thereto, and following terms, as used herein, have the following meanings:

1.1 “” mean the Registration Rights Agreement, the Sponsor Support Agreement, the Stockholder Support
Agreement, and each other agreement, document, instrument or certificate contemplated by this Agreement to be executed in connection with the Domestication and the Merger.

1.2 “” has the meaning set forth in .

1.3 “” means, with respect to any Person, any other Person directly or indirectly Controlling, Controlled by, or
under common Control with such Person.

1.4 “” has the meaning set forth in
.

1.5 “” has the meaning set forth in .

1.6 “” has the meaning set forth in .

1.7 “” has the meaning set forth in .

1.8 “” has the meaning set forth in .

A-1-2

1.9 “” has the meaning set forth
in .

1.10 “” mean “Applicable Taxes” as defined in Internal
Revenue Service Notice 2020-65 (and any corresponding Taxes under comparable state or local tax applicable Law).

1.11
“” means Applicable Wages as defined in Internal Revenue Service Notice 2020-65 (and any corresponding wages under comparable state or local tax applicable Law).

1.12 “” has the meaning set forth in .

1.13 “” means all “employee benefit plans” (as defined in