Company: MIRM
Filing Date: 2025-09-09
Form Type: S-8
Source: 0001759425-25-000045
Chunk: 3

Company: Mirum Pharmaceuticals, Inc.
Filing Date: 2025-09-09
Form: S-8
Chunk 3
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 is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not constitute a part of this Registration Statement, except as so modified or superseded.

## Item 8. Exhibits.
The exhibits to this Registration Statement are listed below:

| Exhibit 
 Number  
 4.1     
 4.2     |     | Description                                                                                                                                                                                                            
 Amended and Restated Certificate of Incorporation of the Registrant (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K, filed with the Commission on July 25, 2019).             
 Amended and Restated Bylaws of the Registrant (incorporated by reference to Exhibit 3.2 to the Registrant’s Current Report on Form 8-K, filed with the Commission on July 25, 2019).                                   |
|:--------|:----|:-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 4.3     |     | Form of Common Stock Certificate of the Registrant (incorporated by reference to Exhibit 4.1 to the Registrant’s Registration Statement on Form S-1 (File No. 333-232251), filed with the Commission on July 8, 2019). |
| 5.1     |     | Opinion of Cooley LLP.                                                                                                                                                                                                 |
| 23.1    |     | Consent of Independent Registered Public Accounting Firm.                                                                                                                                                              |
| 23.2    |     | Consent of Cooley LLP (included in Exhibit 5.1).                                                                                                                                                                       |
| 24.1    |     | Power of Attorney (included on the signature page).                                                                                                                                                                    |
| 99.1    |     | Mirum Pharmaceuticals, Inc. 2020 Inducement Plan, as amended September 4, 2025.                                                                                                                                        |
| 107     |     | Filing Fee Table.                                                                                                                                                                                                      |

### SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Foster City, State of California, on September 9, 2025.

| MIRUM PHARMACEUTICALS, INC. |
| By:/s/