Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 73

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 73
---
 from those currently
affecting the independent results of operations of each of Fifth Third and Comerica. For a discussion of the businesses of Fifth Third and Comerica and of certain factors to consider in connection with those businesses, see the documents
incorporated by reference in this joint proxy statement/prospectus and referred to under “Where You Can Find More Information,” beginning on page 179.

The future results of Fifth Third following the completion of the first merger may suffer if Fifth Third does not effectively manage its expanded operations.

Following the first merger, the size and scope of the business of Fifth Third will increase significantly beyond the current size and
scope of either Fifth Third’s or Comerica’s business. Fifth Third’s future success following the first merger will depend, in part, upon its ability to manage its expanded businesses, which will pose challenges for management,
including challenges related to the management and monitoring of new operations and associated increased costs and complexity. There can be no assurances that Fifth Third will be successful or that it will realize the expected operating
efficiencies, cost savings, revenue synergies and other benefits currently anticipated from the first merger.

50

In addition, following the first merger, Fifth Third will be subject to increased scrutiny by, and
additional regulatory requirements of, bank regulatory authorities as a result of the transaction and the size, scope and complexity of its business operations, which may have an adverse effect on the business, operations or stock price of Fifth
Third.

The fairness opinions delivered by Goldman Sachs and J.P. Morgan, respectively, to Fifth Third’s and Comerica’s respective boards of directors prior to the entry into the merger agreement will not reflect changes in circumstances that may have occurred since the dates of the opinions.

The respective boards of directors of Fifth Third and Comerica have not obtained updated fairness opinions either as of the date of this joint proxy
statement/prospectus or as of any other date subsequent to the dates of such opinions from Goldman Sachs, which is Fifth Third’s financial advisor, or from J.P. Morgan, which is Comerica’s financial advisor. Changes in the operations and
prospects of Fifth Third or Comerica, general market and economic conditions and other factors which may be beyond the control of Fifth Third and Comerica, may have altered the value of Fifth Third or Comerica or the prices of shares of Fifth Third
stock and shares of Comerica stock as of the date of this joint proxy statement/prospectus, or may alter such values