Company: TVRD
Filing Date: 2025-02-14
Form Type: S-4/A
Source: 0001104659-25-013053
Chunk: 402

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-02-14
Form: S-4/A
Chunk 402
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 | ​                                                                           | $ | 86.35 | ​ | ​ | ​ | ​                                                                                                                                | ​ |   494,275 | ​ | ​ |
| Equity compensation plans not approved by security holders | ​ | ​ | ​                                                                                        | ​ |       — | ​ | ​ | ​ | ​                                                                           | $ |     — | ​ | ​ | ​ | ​                                                                                                                                | ​ | 25,000(4) | ​ | ​ |
| Total                                                      | ​ | ​ | ​                                                                                        | ​ | 420,373 | ​ | ​ | ​ | ​                                                                           | $ | 86.35 | ​ | ​ | ​ | ​                                                                                                                                | ​ |   519,275 | ​ | ​ |

(1) Includes the 2014 Plan. (2) Cara grants full value RSUs which skew the weighted average exercise price down since there is no strike price. Excluding RSUs, Cara had 340,460 securities issued from plans approved by security holders, comprised of stock options, with a weighted average exercise price of $106.62 per share. (3) All of these shares are available for future issuance under the 2014 Plan. Further, pursuant to the terms of the 2014 Plan, the aggregate number of shares of common stock reserved for issuance under the 2014 Plan automatically increases on January 1 of each year, through and including January 1, 2024, by 3% of the total number of shares of our capital stock outstanding on December 31 of the preceding calendar year, or a lesser number of shares determined by the Cara Board. (4) Includes shares of common stock issuable pursuant to Cara’s 2019 Inducement Plan (2019 Plan).

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TABLE OF CONTENTS

<div align='center'>**PROPOSAL NO. 4 (THE REVERSE STOCK SPLIT PROPOSAL): APPROVAL OF AN AMENDMENT TO THE CARA AMENDED AND RESTATED CERTIFICATE OF INCORPORATION EFFECTING THE REVERSE STOCK SPLIT AT A RATIO IN THE RANGE FROM 1-FOR-2 TO 1-FOR-4**</div>

#### General
At the Cara special meeting, Cara’s common stockholders will be asked to approve an amendment to the amended and restated certificate of incorporation of Cara effecting the Reverse Stock Split of Cara common stock at a ratio anywhere in the range between one new share for every two shares and one new share for every four shares outstanding. Prior to the