Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 273

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 273
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 on founder notes payable of $34,692 and $35,063 in the years ended May 31, 2025 and
2024, respectively as additional paid-in capital.

Grants Received from Government Agencies

Research and development grants
received from government institutions are recognized as revenue as related research obligations are performed, with qualified expenses
classified as expenses. If grant funds are received in advance of performance, they are initially recognized as liabilities, to the extent
they are refundable.

Since inception, DiamiR has
raised over $9.7 million grant funding from government agencies and disease foundations. On October 1, 2020, DiamiR announced
that it received two grants from the National Institutes of Health (NIH) in the total amount of approximately $3.86 million. The
National Institute on Aging (NIA) awarded the company approximately $3.36 million in a Commercialization Readiness Pilot (CRP) grant
as part of its Small Business Innovation Research (SBIR) program. The award builds upon earlier studies conducted by DiamiR in collaboration
with leading academic centers and continues to support development of CogniMIR, the company’s lead diagnostic product
candidate for early detection and monitoring of mild cognitive impairment and AD. The second award of $498,572 was granted to DiamiR
by the National Institute for Neurological Disorders and Stroke (NINDS) for a project entitled “Circulating Organ-enriched microRNAs
as biomarkers of Rett Syndrome.” As of August 31, 2025, DiamiR has used all of its available grant funding.

Stock-based compensation

Stock-based compensation for
acquiring goods or providing services is recognized at fair value when the goods are obtained or over the service period. If the award
contains performance conditions, the measurement date of the award is the earlier of the date at which a commitment for performance by
the non-employee is reached or the date at which performance is reached. A performance commitment is reached when performance by the non-employee
is probable because of sufficiently large disincentives for nonperformance.

DiamiR issued 44,000 restricted
stock units (“RSUs”) in the fiscal year ending May 31, 2023 as compensation for services, subject to certain vesting
conditions. No compensation expense related to the RSUs was recognized through August 31, 2025, as the vesting condition was not
considered to be probable of achievement for accounting