Company: TAK
Filing Date: 2025-06-25
Form Type: F-3ASR
Source: 0001395064-25-000097
Chunk: 50

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-06-25
Form: F-3ASR
Chunk 50
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 Takeda Pharmaceutical Company Limited, and Amit Singh, Global Head of Treasury of Takeda Pharmaceutical Company Limited, and either of them, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and re-substitution, for such person and in such person’s name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith and about the premises, as fully to all intents and purposes as such person might or could do in person, hereby ratifying and confirming all that said attorney-in-fact and agent or his substitutes or substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirement of the Securities Act of 1933, as amended, this Registration Statement has been signed below by the following persons on behalf of Takeda U.S. Financing, Inc. and in the capacities indicated as of June 25, 2025.

| Signature         |     | Title                                                                                       |
| /s/ Scott Dessing |     | Director and President                                                                      
 (principal executive officer, principal financial officer and principal accounting officer) |
| Scott Dessing     |     |                                                                                             |
| /s/ Fabien Dubois |     | Director and Treasurer                                                                      |
| Fabien Dubois     |     |                                                                                             |

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### SIGNATURE OF AUTHORIZED REPRESENTATIVE IN THE UNITED STATES
Pursuant to the requirements of the Securities Act of 1933, as amended, the undersigned, the duly authorized representative in the United States of Takeda Pharmaceutical Company Limited, has signed this Registration Statement as of June 25, 2025.

KNOW ALL PERSONS BY THESE PRESENTS, that the person whose signature appears below does hereby constitute and appoint Milano Furuta, Director and Chief Financial Officer, and Amit Singh, Global Head of Treasury, and either of them, as his true and lawful attorney-in-fact and agent, with full power of substitution and re-substitution, for him and in his name, place and stead, in any and all capacities, to sign any and all amendments (including post