Company: TEM
Filing Date: 2025-02-25
Form Type: S-1
Source: 0001193125-25-034442
Chunk: 18

Company: Tempus AI, Inc.
Filing Date: 2025-02-25
Form: S-1
Chunk 18
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 its committees, which comply with the applicable requirements of current SEC and Nasdaq rules. We intend to comply with future requirements to the extent applicable. Copies of the charters for the audit committee, the compensation committee and the nominating and corporate governance committee are available on the investor relations portion of our website at https://investors.tempus.com/. The reference to our website address does not constitute incorporation by reference of the information contained at or available through our website, and you should not consider it to be a part of this prospectus. Audit Committee Our audit committee consists of Eric D. Belcher, Peter J. Barris and Wayne A.I. Frederick. Our board of directors has determined that each of Messrs. Belcher, Barris and Frederick satisfies the independence requirements under the Nasdaq Stock Market listing standards and Rule 10A-3(b)(1)of the Exchange Act. The chair of our audit committee is Mr. Belcher. Our board of directors has determined that each of Messrs. Belcher and Frederick is an “audit committee financial expert” within the meaning of SEC regulations. Each member of our audit committee can read and understand fundamental financial statements in accordance with applicable requirements. In arriving at these determinations, our board of directors has examined each audit committee member’s scope of experience and the nature of their employment in the corporate finance sector. The principal duties and responsibilities of our audit committee include, among other things:

| • |     | selecting a qualified firm to serve as the independent registered public accounting firm to audit our 
 financial statements;                                                                                 |

| • |     | helping to ensure the independence and performance of the independent registered public accounting firm; |

| • |     | helping to maintain and foster an open avenue of communication between management and the independent 
 registered public accounting firm;                                                                    |

| • |     | discussing the scope and results of the audit with the independent registered public accounting firm, and 
 reviewing, with management and the independent accountants, our interim and year-end operating results;   |

| • |     | developing procedures for employees to submit concerns anonymously about questionable accounting or audit 
 matters;                                                                                                  |

| • |     | reviewing our policies on risk assessment and risk management; |

| • |     | reviewing related party transactions; |

| • |     | obtaining and reviewing a report by the independent registered public accounting firm at least annually, that                                                              
 describes its internal quality-control procedures, any material issues with such procedures, and any steps taken to deal with such issues when required by applicable law;