Company: CLM
Filing Date: 2025-02-21
Form Type: N-2
Source: 0001398344-25-003234
Chunk: 0

Company: Cornerstone Strategic Investment Fund, Inc.
Filing Date: 2025-02-21
Form: N-2
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission on [●]</div>

1933 Act File No. 333-[●]

1940 Act File No. 811-05150

<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM N-2</div>

Check appropriate box or boxes

| [X]  | REGISTRATION STATEMENT UNDER    
 THE SECURITIES ACT OF 1933      |
| [  ] | PRE-EFFECTIVE AMENDMENT NO. __  |
| [  ] | POST-EFFECTIVE AMENDMENT NO. __ |

<div align='center'>and</div>

| [X] | REGISTRATION STATEMENT UNDER       
 THE INVESTMENT COMPANY ACT OF 1940 |
| [X] | AMENDMENT NO. 22                   |

<div align='center'>Cornerstone Strategic Investment Fund, Inc.

(Registrant Exact Name of as Specified in Charter)

225 Pictoria Drive, Suite 450, Cincinnati, OH 45246

(Address of Principal Executive Offices)

(866) 668-6558

(Registrant’s Telephone Number, including Area
Code)</div>

| Name and Address of Agent       
 for Service:                    | Copies of Communications to: |
| Jesse Hallee                    | Thomas R. Westle, Esq.       |
| c/o Ultimus Fund Solutions, LLC | Blank Rome LLP               |
| 225 Pictoria Drive, Suite 450   | 1271 Avenue of the Americas  |
| Cincinnati, OH 45246            | New York, NY 10020           |

Approximate Date of Proposed Public Offering:As soon as practicable
after the effective date of this Registration Statement.

| [   ] | The only securities being registered                                                                                                      
 on the form are being offered pursuant to a dividend or interest reinvestment plan.                                                       |
| [   ] | Any securities being registered on this                                                                                                   
 form will be offered on a delayed or continuous basis in reliance on Rule 415 under the Securities Act of 1933, (“Securities              
 Act”) other than securities offered in connection with a dividend reinvestment plan.                                                      |
| [   ] | This form is a registration statement pursuant                                                                                            
 to General Instruction A.2 or a post-effective amendment thereto.                                                                         |
| [   ] | This form is a registration statement pursuant                                                                                            
 to General Instruction B or a post-effective amendment ther