Company: CERO
Filing Date: 2025-01-07
Form Type: 424B3
Source: 0001213900-25-001660
Chunk: 2

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-01-07
Form: 424B3
Chunk 2
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 each exchange on which registered |
| Common Stock, par value $0.0001 per share                              |     | CERO              |     | NASDAQ Global Market                      |
| Warrants, each whole warrant exercisable for one share of common stock |     | CEROW             |     | NASDAQ Capital Market                     |

Indicate by check mark whether the registrant
is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 or Rule 12b-2 of the Securities Exchange Act of 1934.

Emerging growth company ☒

If an emerging growth company, indicate by check
mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting
standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements

As previously disclosed, on
October 2, 2024 the Board of Directors (the “Board”) of CERo Therapeutics Holdings, Inc. (the “Company”) appointed
Chris Ehrlich as Interim Chief Executive Officer. On December 2, 2024, the Board approved the appointment of Mr. Ehrlich as Chief
Executive Officer on a permanent, non-interim basis effective immediately. In connection with Mr. Ehrlich’s appointment
as the Company’s permanent Chief Executive Officer, the Company intends to modify the terms of its existing consulting agreement
with Mr. Ehrlich. Such terms will be reported on a Current Report on Form 8-K once agreed.

Item 8.01 Other Events.

On December 6, 2024, the Company
issued a press release announcing Mr. Ehrlich’s appointment as the Chief Executive Officer. The full text of
the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K and incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

The following exhibits are furnished herewith:

| Exhibit No. 
 99.1        |     | Description                                                                  
 Press release, dated December 6, 2024.                                       |
|:------------|:----|:-----------------------------------------------------------------------------|
| 104         |     | Cover Page Interactive Data File (embedded within the Inline XBRL document). |

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