Company: GANX
Filing Date: 2025-04-29
Form Type: DEF 14A
Source: 0001558370-25-005829
Chunk: 9

Company: Gain Therapeutics, Inc.
Filing Date: 2025-04-29
Form: DEF 14A
Chunk 9
---
 these proposals.

#### What are “broker non-votes”?
As discussed above, when a beneficial owner of shares held in “street name” does not give instructions to the broker or nominee holding the shares as to how to vote on matters deemed to be “non-routine,” the broker or nominee cannot vote the shares with respect to that non-routine matter. These unvoted shares are counted as “broker non-votes.” Proposal 1 is expected to be considered “non-routine” and we, therefore, expect broker non-votes to exist in connection with this proposal. Proposal 2, Proposal 3 and Proposal 4 are expected to be considered “routine” matters and, therefore, broker-non-votes are not expected to exist in connection with this proposal.

<div align='center'>6</div>

As a reminder, if you are a beneficial owner of shares held in street name, in order to ensure your shares are voted in the way you would prefer, you must provide voting instructions to your broker, bank or other agent by the deadline provided in the materials you receive from your broker, bank or other agent . How many votes are needed to approve each proposal? The following table summarizes the minimum vote needed to approve each proposal and the effect of abstentions and broker non-votes.

| ​        | ​ | ​                                                                                                                                                   | ​ | ​                                                                                                                                                                                                                                                                                                                           | ​ | ​              | ​ | ​                  |
| Proposal 
 Number   |   | Proposal Description                                                                                                                                |   | Vote Required for Approval                                                                                                                                                                                                                                                                                                  |   | Effect of      
 Abstentions    |   | Effect of          
 Broker Non-        
 Votes              |
| 1        | ​ | Election of Directors                                                                                                                               | ​ | Directors will be elected by a plurality of the votes cast at the Annual Meeting by the holders of shares present by remote communication or represented by proxy and entitled to vote on the election of directors. The eight nominees receiving the most “FOR” votes will be elected; withheld votes will have no effect. | ​ | Not applicable | ​ | No effect          |
| ​        | ​ | ​                                                                                                                                                   | ​ | ​                                                                                                                                                                                                                                                                                                                           | ​ | ​              | ​ | ​                  |
| 2        | ​ | Ratification of the selection of Ernst & Young AG as our independent registered public accounting firm for the fiscal year ending December 31, 2025 | ​ | “FOR” votes from the holders of a majority of shares present in person or represented by proxy and entitled to vote thereon