Company: NCEL
Filing Date: 2025-07-01
Form Type: 425
Source: 0001213900-25-060355
Chunk: 3

Company: NewcelX Ltd.
Filing Date: 2025-07-01
Form: 425
Chunk 3
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| Date:        
 July 1, 2025 | NLS                
 Pharmaceutics Ltd. 
 By:                | /s/             
 Alexander Zwyer |                   |
|:-------------|:-------------------|:----------------|:------------------|
|              |                    | Name:           | Alexander         
 Zwyer             |
|              |                    | Title:          | Chief             
 Executive Officer |

<div align='center'>4</div>

Exhibit 99.1

<div align='center'>FIFTH AMENDMENT TO

AGREEMENT OF MERGER AND PLAN OF REORGANIZATION</div>

This Fifth Amendment to Agreement of Merger and Plan of Reorganization (this “Amendment”) is made and entered into as of July 1, 2025, by and among Kadimastem Ltd., an Israeli publicly traded company limited by shares (the “Company”), NLS Pharmaceutics Ltd., a corporation incorporated under the laws of Switzerland (“Parent”), and NLS Pharmaceuticals (Israel) Ltd., an Israeli company (“Merger Sub”, and together with the Company and Parent, the “Parties”). Capitalized terms used herein without definition shall have the same definition ascribed thereto in the Agreement (as defined below).

WHEREAS, the Agreement of Merger and Plan of Reorganization was made and entered into as of November 4, 2024, as amended as of January 30, 2025, as further amended as of February 17, 2025, as further amended as of May 5, 2025, and as further amended on June 5, 2025, by and among the Company, Parent and Merger Sub (the “Agreement”);

WHEREAS, the Agreement may be amended by an instrument in writing signed on behalf of the Parties thereto; and

WHEREAS, the Parties desire to amend the Agreement as set forth below.

NOW, THEREFORE, in consideration of the mutual promises contained in this Amendment and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties hereby agree as follows:

1. Notwithstanding Section 7.1.1 of the Agreement as amended on January 30, 2025 and as further amended on May 5, 2025, the Termination Date shall be extended from June 30, 2025 to August 31, 2025.

2. Effectiveness; No Other Modifications. This Amendment shall be effective as of the day and year