Company: AZN
Filing Date: 2025-06-26
Form Type: 11-K
Source: 0001683168-25-004771
Chunk: 12

Company: ASTRAZENECA PLC
Filing Date: 2025-06-26
Form: 11-K
Chunk 12
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 |     |         | – |     |         | – |
| Investments measured at net asset value (a) |     |                                                  |               |     |         |              |     |         |   |     |         |   |
| Commingled funds                            |     |                                                  | 5,040,438,572 |     |         |            – |     |         | – |     |         | – |
| Collective trust                            |     |                                                  | 1,800,985,722 |     |         |            – |     |         | – |     |         | – |
| Private equity funds                        |     |                                                  |       986,657 |     |         |            – |     |         | – |     |         |   |
| Total investments at fair value             |     | $                                                | 7,250,832,374 |     | $       | 4708,421,423 |     | $       | – |     | $       | – |

(a)In
accordance with Subtopic 820-10, collective trusts, private equity funds, and commingled funds that were measured at net asset value
per share (or its equivalent) have not been classified in the fair value hierarchy. The fair value amounts presented in this table
are intended to permit reconciliation of the fair value hierarchy to the line items presented in the statement of net assets
available for benefits.

| 12 |

<div align='center'>ASTRAZENECA SAVINGS AND SECURITY PLAN

Notes to Financial Statements

December 31, 2024 and 2023

_______________</div>

| 4. | Fair Value Measurements, continued: |

The availability
of observable market data is monitored to assess the appropriate classification of financial instruments within the fair value hierarchy.
Changes in economic conditions or model-based valuation techniques may require the transfer of financial instruments from one fair value
level to another.

For the years
ended December 31, 2024 and 2023, there were no transfers in or out of level 2 or 3 as there were no level 2 or 3 investments noted.

| 5. | Internal Revenue Service Status: |

The
IRS has determined and informed the Company by a letter dated February 8, 2018, that the Plan and related trust are designed in accordance
with applicable sections of the IRC. Although the Plan has been amended since receiving the determination letter, the Plan administrator
and the Plan’s