Company: NYXH
Filing Date: 2025-03-20
Form Type: F-3
Source: 0001104659-25-026217
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Company: Nyxoah SA
Filing Date: 2025-03-20
Form: F-3
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TABLE OF CONTENTS

As filed with the Securities and Exchange Commission on March 20, 2025 Registration No. 333- UNITED STATES
SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form F-3 REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933 NYXOAH SA (Exact name of registrant as specified in its charter) Not Applicable (Translation of registrant’s name into English)

| ​ | Belgium(State or other jurisdiction ofincorporation or organization) | ​ | ​ | Not Applicable(I.R.S. EmployerIdentification Number) | ​ |

Nyxoah SA
Rue Edouard Belin 12
B-1435 Mont-Saint-Guibert
Belgium
Telephone: +32 10 22 23 55
(Address and telephone number of registrant’s principal executive offices) Corporation Service Company
251 Little Falls Drive, Wilmington, DE 19808
United States
Telephone: +1 302 636 5400
(Name, address, and telephone number of agent for service) Copies to: John T. Rudy, Esq.
Jason S. McCaffrey, Esq.
Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
One Financial Center
Boston, MA 02111
Telephone: +1 617 542 6000
Facsimile: +1 617 542 2241 APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC: From time to time after the effective date of this registration statement. If the only securities being registered on this Form are being offered pursuant to dividend or interest reinvestment plans, please check the following box. ☐ If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, other than securities offered only in connection with dividend or interest reinvestment plans, check the following box. ☒ If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐ If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the