Company: MIRM
Filing Date: 2025-08-12
Form Type: S-3ASR
Source: 0001193125-25-178937
Chunk: 0

Company: Mirum Pharmaceuticals, Inc.
Filing Date: 2025-08-12
Form: S-3ASR
Chunk 0
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As filed with the Securities and Exchange Commission on August 12, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Mirum Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter)

| Delaware                        |     | 83-1281555         |
| (State or other jurisdiction of 
 incorporation organization)     |     | -I.R.S. Employer   
 Identification No. |

Mirum Pharmaceuticals, Inc. 989 East Hillsdale Boulevard, Suite 300 Foster City, California 94404 (650) 667-4085 (Address, including zip code, and telephone number, including area code, of registrant’s principal executive offices) Christopher Peetz, Chief Executive Officer Douglas Sheehy, Chief Legal Officer & Secretary Mirum Pharmaceuticals, Inc. 989 East Hillsdale Boulevard, Suite 300 Foster City, California 94404 (650) 667-4085 (Name, address, including zip code, and telephone number, including area code, of agent for service) Copies to :

| Jason L. Kent                     
 Julia R. Boesch Cooley            
 LLP 55 Hudson Yards               
 New York, New York (212) 479-6000 |     | Eric Bjerkholt                      
 Chief Financial Officer 989         
 East Hillsdale Boulevard, Suite 300 
 Foster City, California 94404       
 (650) 667-4085                      |

From time to time after the effective date of this Registration Statement (Approximate date of commencement of proposed sale to the public) If the only securities being registered on this Form are being offered pursuant to dividend or interest reinvestment plans, please check the following box. ☐ If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, other than securities offered only in connection with dividend or interest reinvestment plans, check the following box. ☒ If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐ If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number