Company: ACHV
Filing Date: 2025-01-10
Form Type: S-8
Source: 0000950170-25-004143
Chunk: 1

Company: ACHIEVE LIFE SCIENCES, INC.
Filing Date: 2025-01-10
Form: S-8
Chunk 1
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 by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.☐

<div align='center'>INTRODUCTORY NOTE

REGISTRATION OF ADDITIONAL SHARES PURSUANT TO GENERAL INSTRUCTION E</div>

Achieve Life Sciences, Inc. (the “Registrant”) is filing this Registration Statement on Form S-8 (the “Registration Statement”) with the Securities and Exchange Commission (the “Commission”) to register (a) 1,734,253 additional shares of common stock under the Registrant’s 2018 Equity Incentive Plan (“EIP”), pursuant to the provisions of the EIP providing for an automatic increase in the number of shares reserved for issuance under the EIP on January 1, 2025 and (b) 346,850 additional shares of common stock under the Registrant’s 2017 Employee Stock Purchase Plan (“ESPP”), pursuant to the provisions of the ESPP providing for an automatic increase in the number of shares reserved for issuance under the ESPP on January 1, 2025. This Registration Statement hereby incorporates by reference the contents of the Registrant’s previous registration statements on Form S-8 filed with the Commission on November 7, 2018 (Registration No.333-22853), May 15, 2019 (Registration No.333-231520), January 24, 2020 (Registration No.333-236059), March 11, 2021 (Registration No.333-254156), March 10, 2022 (Registration No.333-263421), March 16, 2023 (Registration No.333-270625) and March 28, 2024 (Registration No.333-278335) to the extent not superseded hereby.

<div align='center'>PART II

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>

| Item 3. | Incorporation of Documents by Reference. |

The following documents filed by the Registrant with the Commission pursuant to the Securities Act and the Securities Exchange Act of 1934, as amended (the “Exchange Act”) are incorporated herein by reference:

| (b) | all other reports filed pursuant to Section 13(a) or 15(d) of the Exchange Act since the end of the fiscal year covered by the Registrant’s Annual Report referred to in (a) above