Company: PGEN
Filing Date: 2025-08-19
Form Type: S-3
Source: 0000950103-25-010472
Chunk: 2

Company: PRECIGEN, INC.
Filing Date: 2025-08-19
Form: S-3
Chunk 2
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<div align='center'>Precigen, Inc.

143,809,489 Shares of Common Stock
79,000 Shares of Preferred Stock</div>

This prospectus relates to the resale, from time
to time, by the selling stockholders identified herein, of up to 143,809,489 shares of our common stock (“Common Stock”),
no par value per share, and up to 79,000 shares of our 8.00% Series A Convertible Perpetual Preferred Stock (“Preferred Stock”),
no par value per share. The shares offered by the selling stockholders consist of 82,176,842 shares of Common Stock issuable upon conversion
of the Preferred Stock and 61,632,647 shares of Common Stock issuable upon exercise of the warrants (“Warrants”) that, along
with the Preferred Stock, were issued to the selling stockholders in connection with a private placement (the “Private Placement”)
on December 30, 2024. We are not selling any shares of Common Stock or Preferred Stock under this prospectus and will not receive any
proceeds from the sale of shares of Common Stock or Preferred Stock by the selling stockholders. The selling stockholders will bear all
commissions and discounts, if any, attributable to the sale of the shares.

The selling stockholders may sell the shares of
our Common Stock and Preferred Stock offered by this prospectus from time to time on terms to be determined at the time of sale through
ordinary brokerage transactions or through any other means described in this prospectus under the caption “Plan of Distribution.”
The shares of Common Stock and Preferred Stock may be sold at fixed prices, at market prices prevailing at the time of sale, at prices
related to prevailing market price or at negotiated prices.

Our Common Stock is listed on the Nasdaq Global
Select Market under the symbol “PGEN”. On August 18, 2025, the last reported sale price of our Common Stock on the Nasdaq
Global Select Market was $2.95 per share. There is no established trading market for our Preferred Stock, and we do not expect a market
to develop. Our Preferred Stock is not currently listed on any securities exchange. While there is no established public trading market
for our Preferred Stock, we believe the actual offering price in sales of our Preferred Stock by the selling stockholders will be derived
from the prevailing market price of our Common Stock at the time of any such sale.

<div align='center'>Investing in our