Company: SFNC
Filing Date: 2025-07-23
Form Type: 424B5
Source: 0001193125-25-162761
Chunk: 41

Company: SIMMONS FIRST NATIONAL CORP
Filing Date: 2025-07-23
Form: 424B5
Chunk 41
---
,                
 whose corporate purpose is solely to invest in securities or otherwise in circumstances which do not require the publication by us of a prospectus pursuant to the prospectus rules of the Financial Conduct Authority made under Section 73A of the 
 FSMA;                                                                                                                                                                                                                                                |

| • |     | it has only communicated or caused to be communicated and will only communicate or cause to be communicated an                                                                                                                       
 invitation or inducement to engage in investment activity (within the meaning of Section 21 of FSMA) received in connection with this offering in circumstances in which Section 21(1) of the FSMA does not apply to the issuer; and |

| • |     | it has complied with, and will comply with, all applicable provisions of FSMA with respect to anything done by it 
 in relation to the securities in, from or otherwise involving the United Kingdom.                                 |

European Economic Area In relation to each Member State of the European Economic Area that has implemented the Prospectus Directive (as defined below), each referred to as a Relevant Member State, each underwriter has represented and S-33

agreed that with effect from and including the date on which the Prospectus Directive is implemented in that Relevant Member State, referred to as the Relevant Implementation Date, it has not made and will not make an offer of the securities which are the subject of the offering contemplated by this prospectus supplement to the public in that Relevant Member State other than:

| • |     | to any legal entity which is a qualified investor as defined in the Prospectus Directive; |

| • |     | to fewer than 150 natural or legal persons (other than qualified investors as defined in the Prospectus 
 Directive) in such Relevant Member State; or                                                            |

| • |     | in any other circumstances falling within Article 3(2) of the Prospectus Directive; provided, that no such offer                     
 of securities shall require the issuer or any underwriter to publish a prospectus pursuant to Article 3 of the Prospectus Directive. |

Each person in a Relevant Member State who receives any communication in respect of, or who acquires any securities under, the offer contemplated in this prospectus supplement will be deemed to have represented, warranted and agreed to and with us and each underwriter that:

| • |     | it is a qualified investor as defined in the Prospectus Directive; and |

| • |     | in the case of any securities acquired by it as a financial intermediary, as that term is used in                                                                                                                                                   
 Article 3(2