Company: TEM
Filing Date: 2025-03-07
Form Type: 424B3
Source: 0001193125-25-049935
Chunk: 18

Company: Tempus AI, Inc.
Filing Date: 2025-03-07
Form: 424B3
Chunk 18
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 recommending that our board of directors approve, incentive compensation and 
 equity plans;                                                                                            |

| • |     | overseeing our compensation clawback or similar policies; and |

| • |     | reviewing and establishing general policies relating to compensation and benefits of our employees and 
 reviewing our overall compensation philosophy.                                                         |

Nominating and Corporate Governance Committee Our nominating and corporate governance committee consists of Theodore J. Leonsis, Jennifer A. Doudna and Scott Gottlieb. The chair of our nominating and corporate governance committee is Mr. Leonsis. Our board of directors has determined that each member of the nominating and corporate governance committee is independent under the applicable listing standards of the Nasdaq Stock Market. In addition, Mr. Lefkofsky serves as an observer on our nominating and corporate governance committee. The nominating and corporate governance committee’s responsibilities include, among other things:

| • |     | identifying, evaluating, and selecting, or recommending that our board of directors approve, nominees for 
 election to our board of directors and its committees;                                                    |

| • |     | approving the retention of director search firms; |

| • |     | evaluating the performance of our board of directors and of individual directors; |

| • |     | considering and making recommendations to our board of directors regarding the composition of our board of 
 directors and its committees;                                                                              |

| • |     | evaluating the adequacy of our corporate governance practices and reporting; |

| • |     | overseeing our ESG activities, as applicable; and |

| • |     | overseeing an annual evaluation of the board’s performance. |

Executive Committee Our board of directors has established an executive committee comprised of Peter J. Barris, Theodore J. Leonsis and Eric Lefkofsky. The executive committee was formed to facilitate approval of certain corporate 12

actions in the intervals between full meetings of the board. The executive committee has the authority to exercise the power and authority of the board, except with respect to matters which, under the Delaware General Corporation Law or the rules and regulations of the Nasdaq Stock Market, cannot be delegated by the board of directors to a committee. Code of Conduct We have adopted a Code of Conduct that applies to all our employees, officers and directors. This includes our principal executive officer, principal financial officer and principal accounting officer or controller, or persons performing similar functions. The full text of our Code of Conduct is available on the investor relations portion of our website at https://investors.tempus.com/.