Company: PFSA
Filing Date: 2025-08-15
Form Type: 8-K/A
Source: 0001213900-25-076867
Chunk: 0

Company: Profusa, Inc.
Filing Date: 2025-08-15
Form: 8-K/A
Chunk 0
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<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K/A

(Amendment No. 1)

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF THE

SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported):
July 11, 2025

PROFUSA, INC.

(Exact name of registrant as specified in its charter)</div>

| Delaware                     |     | 001-41177               |     | 86-3437271         |
| (State or other jurisdiction 
 of incorporation)            |     | -Commission File Number |     | -IRS Employer      
 Identification No. |

<div align='center'>626 Bancroft Way, Suite A

Berkeley, CA 94710

(Address of principal executive offices, including
zip code)

Registrant’s telephone number, including
area code: ( 925) 997-6925

Not Applicable

(Former name or former address, if changed since
last report)</div>

Check the appropriate box below if the Form 8-K
filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

| ☐ | Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |

| ☐ | Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |

| ☐ | Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |

| ☐ | Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |

Securities registered pursuant to Section 12(b)
of the Act:

| Title of each class                       |     | Trading Symbol(s) |     | Name of each exchange on which registered |
| Common Stock, par value $0.0001 per share |     | PFSA              |     | The Nasdaq Stock Market LLC               |

Indicate by check mark whether the registrant
is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the
Securities