Company: DRTSW
Filing Date: 2025-03-12
Form Type: S-8
Source: 0001213900-25-023243
Chunk: 1

Company: Alpha Tau Medical Ltd.
Filing Date: 2025-03-12
Form: S-8
Chunk 1
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If an emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
to Section 7(a)(2)(B) of the Securities Act. ☐

<div align='center'>EXPLANATORY NOTE</div>

Pursuant to General Instruction E of Form S-8, Alpha Tau Medical Ltd.
(the “Registrant,” “we” or “our”) is filing this Registration Statement with the Securities and Exchange
Commission (the “SEC”) to register (i) 2,815,223 additional ordinary shares, no par value (“Ordinary Shares”),
of the Registrant reserved for issuance under the Alpha Tau Medical Ltd. 2021 Share Incentive Plan (the “2021 Plan”) resulting
from an automatic annual increase as of January 1, 2025 and (ii) 703,806 additional Ordinary Shares reserved for issuance under the Alpha
Tau Medical Ltd. 2021 Employee Share Purchase Plan (the “ESPP”) resulting from an automatic annual increase as of January
1, 2025. This Registration Statement hereby incorporates by reference the contents of the Registrant’s Registration Statements on
Form S-8 filed with the SEC on April 7, 2022 (File No. 333-264169), March 9, 2023 (File No. 333-270406) and March 7, 2024 (File No. 333-277733).

<div align='center'>PART I

INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>

The information called for in Part I of Form S-8 is not being filed
with or included in this Form S-8 (by incorporation by reference or otherwise) in accordance with the rules and regulations of the SEC.

<div align='center'>1

PART II

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>

Item 3. Incorporation of Documents by Reference.

The SEC allows us to incorporate by reference the information we file
with them, which means that we can disclose important information to you by referring you to those documents. The information incorporated
by reference is considered to be part of this Registration Statement, and later information filed with the SEC will update and supersede
this information. We hereby incorporate by reference into this Registration Statement the following documents filed or to be filed with
the SEC:

| (b) | The description of