Company: PRME
Filing Date: 2025-11-07
Form Type: 10-Q
Source: 0001628280-25-050422
Chunk: 64

Company: Prime Medicine, Inc.
Filing Date: 2025-11-07
Form: 10-Q
Item: Part I, Item 8
Chunk 64
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2,997 $1 $— $2,998 Total short-term investments in debt securities$2,997 $1 $— $2,998 The contractual maturities of the Company’s investments in debt securities were as follows:(in thousands)September 30,2025December 31,2024Due within one year$137,030 $2,998 Marketable securities in unrealized loss positions consisted of the following: As of September 30, 2025:(in thousands, except number of securities)Number of SecuritiesFair ValueGross Unrealized LossesInvestments in continuous loss position for less than 12 months:U.S. Treasury and government securities5 $4,489 $(1)Corporate debt securities16 $25,707 $(6)Based on factors such as historical experience, market data, issuer-specific factors, and current economic conditions, the Company did not record an allowance for credit losses as of September 30, 2025 related to these investments. Further, given the lack of significant change in the credit risk, the Company does not consider these investments to be impaired.

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4.Property and Equipment, Net 

Property and equipment, net consisted of the following:(in thousands)September 30,2025December 31,2024Property and equipment:Laboratory equipment$29,685 $27,343 Leasehold improvement7,911 5,136 Furniture and Fixture1,864 1,075 Computer hardware and software1,122 869 Construction in progress21 3,578 Total property and equipment40,603 38,001 Less: Accumulated depreciation(18,557)(13,597)Total property and equipment, net$22,046 $24,404 Depreciation expense related to property and equipment is as follows:Three Months Ended September 30,Nine Months Ended September 30,(in thousands)2025202420252024Depreciation Expense$1,881 $1,558 $5,445 $4,411 

5.Accrued Expenses and Other Current Liabilities

Accrued expenses and other current liabilities consisted of the following:(in thousands)September 30,2025December 31,2024Accrued expenses and other current liabilitiesEmployee compensation and benefits$6,759 $8,976 License fee1,562 1,938 Research and clinical costs619 907