Company: AZN
Filing Date: 2025-12-01
Form Type: 6-K
Source: 0001654954-25-013569
Chunk: 0

Company: ASTRAZENECA PLC
Filing Date: 2025-12-01
Form: 6-K
Chunk 0
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#### FORM 6-K
<div align='center'>SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Report of Foreign Issuer

Pursuant to Rule 13a-16 or 15d-16 of

the Securities Exchange Act of 1934

For the month of December 2025

Commission File Number: 001-11960</div>

#### AstraZeneca PLC
<div align='center'>1 Francis Crick Avenue

Cambridge Biomedical Campus

Cambridge CB2 0AA

United Kingdom

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F X Form 40-F __

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ______

Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

Yes __ No X

If “Yes” is marked, indicate below the file number assigned to the Registrant in connection with Rule 12g3-2(b): 82-_____________</div>

#### AstraZeneca PLC
<div align='center'>INDEX TO EXHIBITS</div>

1. Block listing Interim Review

1 December 2025

### BLOCK LISTING SIX MONTHLY RETURN
Information provided on this form must be typed or printed electronically and provided to a PIP .

(Note: Italicised terms have the same meaning as given in the Listing Rules.)

Date : 1 December 2025

| Name ofapplicant:                                                |       |                                                   ASTRAZENECA PLC |     |                  |
| Name of scheme:                                                  |       |                        ASTRAZENECA SHARE OPTION PLAN; ASTRAZENECA 
                                              SAVINGS-RELATEDSHARE 
 OPTION PLAN; ASTRAZENECA ALL-EMPLOYEE SHARE PLAN; ASTRAZENECA PLC 
                          2012 SAVINGS-RELATED SHARE OPTION SCHEME |     |                  |
| Period of return:                                                | From: |                                                       1 JUNE 2025