Company: NCEL
Filing Date: 2025-10-24
Form Type: POS AM
Source: 0001213900-25-102149
Chunk: 1

Company: NewcelX Ltd.
Filing Date: 2025-10-24
Form: POS AM
Chunk 1
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 following box and list the Securities Act registration statement
number of the earlier effective registration statement for the same offering. ☐

If this form is a post-effective amendment filed
pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of
the earlier effective registration statement for the same offering. ☐

If this form is a post-effective amendment filed
pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number of
the earlier effective registration statement for the same offering. ☐

Indicate by check mark whether the registrant
is an emerging growth company as defined in Rule 405 of the Securities Act of 1933.

Emerging growth company ☒

If an emerging growth company that prepares its
financial statements in accordance with U.S. GAAP, indicate by check mark if the registrant has elected not to use the extended transition
period for complying with any new or revised financial accounting standards † provided pursuant to Section 7(a)(2)(B) of the Securities
Act. ☐

The registrant hereby amends this registration statement on such date or dates as may be necessary to delay its effective date until the registrant shall file a further amendment which specifically states that this registration statement shall thereafter become effective in accordance with Section 8(a) of the Securities Act or until the registration statement shall become effective on such date as the Commission, acting pursuant to said Section 8(a), may determine.

<div align='center'>EXPLANATORY NOTE</div>

This Post-Effective Amendment
No. 1, or this Post-Effective Amendment, to the Registration Statement on Form F-1 (File No. 333-290516), or the Registration Statement,
is being filed pursuant to NLS Pharmaceutics Ltd.’s, or NLS, undertaking in the Registration Statement to update and supplement
information contained in the Registration Statement, as originally filed and declared effective by the Securities and Exchange Commission,
or the SEC, on September 30, 2025, to incorporate by reference NLS’s Reports on Form 6-K furnished with the SEC on September 30,
2025 (except for the fifth and sixth paragraphs in the press release attached as Exhibit 99.1), October 6, 2025 and October 10, 2025.

The information included
in this filing updates the Registration Statement and the prospectus contained therein. No additional