Company: BFRG
Filing Date: 2025-04-25
Form Type: 424B5
Source: 0001641172-25-006297
Chunk: 0

Company: BullFrog AI Holdings, Inc.
Filing Date: 2025-04-25
Form: 424B5
Chunk 0
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Filed pursuant to Rule 424(b)(5)

Registration No. 333-281341

PROSPECTUS SUPPLEMENT

(To the Prospectus dated August 21, 2024)

<div align='center'>Bullfrog AI Holdings, Inc.

Up to $3.1 million

Of Shares of Common Stock</div>

We have entered into an At-the-Market Sales Agreement, or the Sales Agreement, with BTIG, LLC, or the sales agent, relating to shares of our common stock offered by this prospectus supplement. In accordance with the terms of the Sales Agreement, we may offer and sell shares of our common stock, $0.00001 par value per share, of our common stock, having an aggregate offering price of up to $20,000,000 from time to time through the sales agent.

Our common stock is listed on the Nasdaq Capital Market under the symbol “BFRG.” On April 24, 2025, the last reported sale price of our common stock was $1.84 per share. As of April 24, 2025, the aggregate market value of our outstanding common stock held by non-affiliates (the “Public Float”), was approximately $18.7 million based on 9,415,525 total shares of outstanding common stock, of which approximately 7,003,487 shares were held by non-affiliates, and a price of $2.67 per share, which was the closing price of our common stock on the Nasdaq Capital Market on February 24, 2025. Pursuant to General Instruction I.B.6 of Form S-3, in no event will we sell securities registered in a public primary offering with a value exceeding more than one-third of our Public Float in any 12-calendar month period so long as our public float remains below $75.0 million. We have not offered any securities pursuant to General Instruction I.B.6 of Form S-3 during the prior 12 calendar month period that ends on and includes the date of this prospectus supplement, other than our offering of shares of common stock and pre-funded warrants pursuant to a prospectus supplement dated October 18, 2024, having an aggregate value of $3,129,930. As of April 24, 2025, one-third of the Public Float was equal to approximately $6.2 million, leaving approximately $3.1 million available for issuance in this Sales Agreement.

Sales of our common stock, if any,