Company: CERO
Filing Date: 2025-05-27
Form Type: POS AM
Source: 0001213900-25-047469
Chunk: 256

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-05-27
Form: POS AM
Chunk 256
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 the Common Stock issuable under the Keystone Purchase Agreements is determined on each Fixed Purchase Date, with respect to a Fixed Purchase, on the applicable VWAP Purchase Date, with respect to a VWAP Purchase, and on the applicable Additional VWAP Purchase Date, with respect to an Additional VWAP Purchase, the number of shares that may actually be sold by us to the Selling Securityholder under the Keystone Purchase Agreements may be more or fewer than the number of shares being offered by this prospectus. We may amend or supplement this prospectus from time to time in the future to update or change and the securities that may be resold. Please see the section titled “ Plan of Distribution” for further information regarding the Selling Securityholder’s method of distributing these securities. 147

|                                    |     |       Common Stock 
 Beneficially Owned |     |      Maximum Number 
     of Common Stock 
       to be Offered 
         Pursuant to |     | Common           
 Stock Owned      
 After this       
 Offering (1) (2) |           |     |             |      |   |
| Name of Selling Securityholder     |     |      Prior to this 
   Offering (1) (2) |     | this Prospectus (2) |     | Number of        
 Shares           |           |     | Percent (3) |      |   |
| Keystone Capital Partners, LLC (4) |     |            268,000 |     |           2,100,000 |     |                  | 2,368,000 |     |             | 22.9 | % |

| (1) | Beneficial ownership as reflected in this table reflects the total number of shares of Common Stock, without including the potentially issuable underlying the Preferred Shares and Warrants, and does not give effect to the various limitations on the conversion of the Preferred Shares and exercise of the Warrants. Accordingly, actual beneficial ownership, as calculated in accordance with Section 13(d) and Rule 13d-3 thereunder may be lower than as reflected in the table. The number of shares of Common Stock beneficially owned after the offering assumes the sale of all shares being offered pursuant to this prospectus. In accordance with Rule 13d-3(d) under the Exchange Act, we have excluded from the number of shares beneficially owned prior to the offering all of the shares that Selling Securityholder may be required to purchase under the respective Purchase Agreements, because the issuance of such shares is solely at our discretion and is subject to