Company: NDRA
Filing Date: 2025-05-09
Form Type: DRS
Source: 0001654954-25-005304
Chunk: 2

Company: ENDRA Life Sciences Inc.
Filing Date: 2025-05-09
Form: DRS
Chunk 2
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, dated   , 2025 |

<div align='center'>Shares of Common Stock</div>

We are offering shares of common stock, par value $0.0001 per share (“common stock”).

Our common stock trades on the Nasdaq Capital Market under the symbol “NDRA.” The assumed public offering price for each share of common stock for purposes of this preliminary prospectus is $ (equal to the last sale price of our common stock as reported by The Nasdaq Capital Market on , 2025). The actual public offering price per each share of common stock in this offering will be determined between us and the Underwriter (defined below) at the time of pricing and may reflect a discount to the current market price for our common stock. Therefore, the recent market price used throughout this preliminary prospectus as a basis for an assumed public offering price per share of common stock may not be indicative of the final offering price.

We have engaged (the “Underwriter”), to act as our exclusive underwriter in connection with this offering. We have agreed to pay to the Underwriter the fees set forth in the table below. We will bear all costs associated with the offering. See “Underwriting” on page 20 of this prospectus for more information regarding these arrangements.

We will have one closing for all the securities purchased in this offering. The public offering price per share of common stock will be fixed for the duration of this offering.

|                                  |     | Per share |     | Total |
|:---------------------------------|:----|:----------|:----|:------|
| Public offering price            |     | $         |     | $     |
| Underwriter fees (1)             |     | $         |     | $     |
| Proceeds, before expenses, to us |     | $         |     | $     |

____________

| (1) | We have agreed to pay the Underwriter a cash fee equal to percent ( %) of the gross proceeds of this offering. This does not include the reimbursement of certain expenses of the Underwriter we have agreed to pay. See “Plan of Distribution” for additional disclosure regarding the compensation to be received by the Underwriter. |

We have granted the Underwriter a [30]-day option to purchase from us up to an additional shares of common stock, at $ per share, less the underwriting discount and commissions. If the Underwriter exercises this option in full, the total underwriting discounts and commissions payable will be $ and the total proceeds to us,