Company: SCLXW
Filing Date: 2025-07-23
Form Type: 424B3
Source: 0001193125-25-163077
Chunk: 178

Company: Scilex Holding Co
Filing Date: 2025-07-23
Form: 424B3
Chunk 178
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(i) those certain Warrant Exchange Agreements, dated as of July 22, 2025 (each, a “Warrant Exchange Agreement”), each by and between the Company and a holder, in exchange for that certain Warrant to Purchase Common Stock
(each an “Existing Tranche B Warrant”), which Existing Tranche B Warrant was originally issued pursuant to Section 1 of that certain Securities Purchase Agreement, dated as of October 7, 2024 (the “Subscription Date”), by and among the Company and the investors (the “Buyers”) referred to therein, as amended from time to time (as amended by the Warrant Exchange Agreements, the “Securities Purchase Agreement”) and
(ii) the Company’s Registration Statement on Form S-3 (File number 333-276245) (the “Original Registration Statement”), which registration
statement was subsequently converted to a registration statement on Form S-1 to continue the registration of the shares of Common Stock issuable by the Company upon exercise of the Existing Tranche B
Warrants (File No. 333-280882) (the Original Registration Statement, as so continued and as the same may be amended from time to time, the “Continuation Registration Statement”) due to
the Company’s ineligibility to use a Form S-3.

1.

(a) . Subject to the terms and conditions hereof (including, without limitation, the limitations
set forth in Section 1(f)), this Warrant may be exercised by the Holder on any day on or after the Exchange Date (an “Exercise Date”), in whole or in part, by delivery (whether via facsimile or otherwise) of a written notice,
in the form attached hereto as Exhibit A (the “Exercise Notice”), of the Holder’s election to exercise this Warrant. Within one (1) Trading Day following an exercise of this Warrant as aforesaid, the Holder
shall deliver payment to the Company of an amount equal to the Exercise Price in effect on the date of such exercise multiplied by the number of Warrant Shares as to which this Warrant was so exercised (the “Aggregate Exercise Price”) in cash or via wire transfer of immediately

available funds if the Holder did not notify the Company in such Exercise Notice that such exercise was made pursuant to a Cashless Exercise (as defined in Section 1(d)). The Holder shall
not be required to deliver the original of this Warrant in order to effect an exercise hereunder. Execution and delivery