Company: PFSA
Filing Date: 2025-11-14
Form Type: NT 10-Q
Source: 0001213900-25-110883
Chunk: 1

Company: Profusa, Inc.
Filing Date: 2025-11-14
Form: NT 10-Q
Chunk 1
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 day following the prescribed due date; and |

| (c) | The accountant's statement or other exhibit required by Rule 12(b)-25(c) has been attached if applicable. |

PART III - NARRATIVE

State below in reasonable detail why Forms 10-K, 20-F, 11-K, 10-Q, 10-D, N-SAR, N-CSR, or the transition report or portion thereof, could not be filed within the prescribed time period.

Profusa, Inc. (the “Registrant”) will
be unable to file its Quarterly Report on Form 10-Q (the “Form 10-Q”) for the fiscal quarter ended September 30, 2025, by
November 14, 2025. The Registrant cannot file its Form 10-Q within the prescribed period without undue hardship and expense because additional
time is needed to finalize the disclosures to be included in such report. The Registrant expects to file the Form 10-Q no later than the
fifth calendar day following the prescribed filing date.

PART IV - OTHER INFORMATION

(1) Name and telephone number of person to contact
in regard to this notification:

| Ben Hwang |     |        925 |     | 997-6925          |
| (Name)    |     | -Area Code |     | -Telephone Number |

(2) Have all other periodic reports required under
Section 13 or 15(d) of the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940 during the preceding 12
months or for such shorter period that the registrant was required to file such report(s) been filed? If answer is no, identify report(s).

☐
Yes ☒ No

Report on Form 8-K, filed July 18, 2025, was not
timely.

(3) Is it anticipated that any significant change
in results of operations from the corresponding period for the last fiscal year will be reflected by the earnings statements to be included
in the subject report or portion thereof?

☐
Yes ☒ No

If so, attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reasons why a reasonable estimate of the results cannot be made.

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| Profusa, Inc.                                |
| (Name of Registrant as Specified in Charter) |

has caused this notification to be signed on