Company: RPTX
Filing Date: 2025-04-29
Form Type: DEF 14A
Source: 0001193125-25-103764
Chunk: 2

Company: Repare Therapeutics Inc.
Filing Date: 2025-04-29
Form: DEF 14A
Chunk 2
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docs.com/RPTXafter logging in with your Control Number, during the entirety of the registration period. Please refer to the additional logistical details and recommendations in the accompanying proxy statement.

The record date for the Annual Meeting is April 21, 2025. Only shareholders of record at the close of business on April 21, 2025 may vote at the Annual Meeting or any adjournment thereof.

By Order of the Board of Directors,

Steve Forte

President, Chief Executive Officer, Chief Financial Officer and Director

St-Laurent, Québec, Canada

April 29, 2025

You are cordially invited to attend the Annual Meeting. Whether or not you expect to attend the Annual Meeting, PLEASE VOTE YOUR SHARES. As an alternative to voting online during the Annual Meeting, you may vote your shares by proxy in advance of the Annual Meeting via the internet, by telephone or, if you receive a paper proxy card, by mailing the completed proxy card. Voting instructions are provided in the Notice of Internet Availability of Proxy Materials, or, if you receive a paper proxy card by mail, the instructions are printed on your proxy card.

Even if you have voted by proxy, you may still vote online during the Annual Meeting if you attend the Annual Meeting webcast. Please note, however, that if your shares are held of record by a broker, bank or other nominee and you wish to vote at the Annual Meeting, you must obtain a proxy issued in your name from that record holder.**

<div align='center'>**REPARE THERAPEUTICS INC.

7171 Frederick-Banting, Building 2, Suite 270

St-Laurent, Québec, Canada H4S 1Z9

PROXY STATEMENT

FOR THE 2025 ANNUAL MEETING OF SHAREHOLDERS

To be Held on June 17, 2025 at 10:00 a.m., Eastern Time**</div>

Our board of directors is soliciting your proxy to vote at the 2025 Annual Meeting of Shareholders (the “Annual Meeting”) of Repare Therapeutics Inc., a corporation incorporated under the Business Corporations Act (Québec), to be held virtually, via live webcast, on Tuesday, June 17, 2025 at 10:00 a.m., Eastern Time, and any adjournment or postponement thereof. Shareholders attending the Annual Meeting virtually will be afforded the same rights and opportunities to participate as they would receive at an in-person meeting. We believe