Company: PAYX
Filing Date: 2025-04-08
Form Type: 424B2
Source: 0001193125-25-075170
Chunk: 77

Company: PAYCHEX INC
Filing Date: 2025-04-08
Form: 424B2
Chunk 77
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| • |     | any delayed delivery arrangements; |

| • |     | any underwriting discounts and commissions or agency fees and other items constituting underwriters’ or 
 agents’ compensation;                                                                                   |

| • |     | any discounts or concessions allowed or reallowed or paid to dealers; and |

| • |     | any securities exchanges on which the securities may be listed. |

Any initial public offering price and any discounts or concessions allowed or reallowed or paid to dealers may be changed from time to time. If we use underwriters in the sale, the securities will be acquired by the underwriters for their own account and may be resold from time to time in one or more transactions, including:

| • |     | negotiated transactions; |

| • |     | at a fixed public offering price or prices, which may be changed; |

| • |     | at market prices prevailing at the time of sale; |

| • |     | at market prices prevailing at the time of sale; or |

| • |     | at negotiated prices. |

Unless otherwise stated in a prospectus supplement, the obligations of the underwriters to purchase any securities will be conditioned on customary closing conditions and the underwriters will be obligated to purchase all securities of a series, if any are purchased. We may sell the securities through agents from time to time. The prospectus supplement will name any agent involved in the offer or sale of the securities and any commissions we pay to them. Generally, any agent will be acting on a best efforts basis for the period of its appointment. We may authorize underwriters, dealers or agents to solicit offers by certain purchasers to purchase the securities from us at the public offering price set forth in the prospectus supplement pursuant to delayed delivery contracts providing for payment and delivery on a specified date in the future. The contracts will be subject only to those conditions set forth in the prospectus supplement, and the prospectus supplement will set forth any commissions paid for solicitations of these contracts. 16

Underwriters and agents may be entitled under agreements entered into with us to
indemnifications by us against certain civil liabilities, including liabilities under the Securities Act, or to contribution with respect to payments which the underwriters or agents may be required to make. Underwriters and agents may be customers
of, engage in transactions with, or perform services for us and our affiliates in the ordinary course of business.

Each series of
securities will be a new issue of securities and will have no established trading market. Any under