Company: SMNR
Filing Date: 2025-12-03
Form Type: S-8
Source: 0001193125-25-306962
Chunk: 25

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-12-03
Form: S-8
Chunk 25
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 Registrant on September 26, 2025). |
|:--------|:----|:-------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 5.1*    |     | Opinion of Paul Hastings LLP.                                                                                                                                      |
| 23.1*   |     | Consent of Pipara & Co LLP, independent registered public accounting firm of Semnur Pharmaceuticals, Inc.                                                          |
| 23.2*   |     | Consent of Paul Hastings LLP (included in Exhibit 5.1).                                                                                                            |
| 24.1*   |     | Power of Attorney is contained on the signature page.                                                                                                              |
| 99.1    |     | 2024 Semnur Pharmaceuticals, Inc. Stock Option Plan. (incorporated by reference to Exhibit                                                                         
 10.12 to the Registration Statement on Form S-4 (File No. 333-283019) filed by the Registrant).                                                                    |
| 99.2    |     | Form of Stock Option Grant Notice and Form of Stock Option Agreement under 2024 Semnur Pharmaceuticals, Inc. Stock Option Plan (incorporated                       
 by reference to Exhibit 10.13 to the Registration Statement on Form S-4 (File No. 333-283019) filed by the Registrant).                                            |
| 107*    |     | Filing Fee Table                                                                                                                                                   |

| * | Filed herewith. |

II-3

ITEM 9. UNDERTAKINGS.

(a) The Registrant hereby undertakes:

(1) To
file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

(i) To
include any prospectus required by Section 10(a)(3) of the Securities Act;

(ii) To reflect in the prospectus any facts or events
arising after the effective date of this Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this Registration
Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the
estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20% change in the maximum
aggregate offering price