Company: XXII
Filing Date: 2025-08-26
Form Type: 424B5
Source: 0001641172-25-025541
Chunk: 56

Company: 22nd Century Group, Inc.
Filing Date: 2025-08-26
Form: 424B5
Chunk 56
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’ obligations to purchase the securities under the securities purchase contracts. The securities purchase contracts may require holders to secure their obligations under the securities purchase contracts in a specified manner. The securities purchase contracts also may require us to make periodic payments to the holders thereof or vice versa, and those payments may be unsecured or refunded on some basis.

The securities purchase contracts, and, if applicable, collateral or depositary arrangements, relating to the securities purchase contracts, will be filed with the SEC in connection with the offering of securities purchase contracts. The prospectus supplement and/or other offering material relating to a particular issue of securities purchase contracts will describe the terms of those securities purchase contracts, including the following:

| ● | if                                                                               
 applicable, a discussion of material U.S. federal income tax considerations; and |

| ● | any                                                                              
 other information we think is important about the securities purchase contracts. |

| 19 |

<div align='center'>DESCRIPTION OF UNITS</div>

As specified in the applicable prospectus supplement, we may issue units consisting of one or more shares of common stock, shares of preferred stock, debt securities, warrants, subscription rights and securities purchase contracts, or any combination of the foregoing.

The applicable prospectus supplement will specify the following terms of the units:

| ● | the                                                                                                                               
 terms of the underlying securities comprising the units, including whether and under what circumstances the underlying securities 
 may be traded separate of the units;                                                                                              |

| ● | a                                                                            
 description of the terms of any unit agreement governing the units (if any); |

| ● | if                                                                                
 appropriate, a discussion of material U.S. federal income tax considerations; and |

| ● | a                                                                                             
 description of the provisions for the payment, settlement, transfer or exchange of the units. |

| 20 |

<div align='center'>PLAN OF DISTRIBUTION</div>

We may sell securities in any one or more of the following ways from time to time: (i) through agents; (ii) to or through underwriters; (iii) through brokers or dealers; (iv) directly to purchasers, including through a specific bidding, auction or other process; (v) upon the exercise of subscription rights that may be distributed to our stockholders; (vi) through a combination of any of these methods of sale or (vii) through any other methods described in a prospectus supplement. The applicable prospectus supplement and/or other offering material will contain the terms of the transaction, name or names of any underwriters, dealers, agents and