Company: RGNX
Filing Date: 2025-11-26
Form Type: S-3
Source: 0001193125-25-300539
Chunk: 22

Company: REGENXBIO Inc.
Filing Date: 2025-11-26
Form: S-3
Chunk 22
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 these amounts will be determined;         |

| • |     | the place or places of payment, transfer, conversion and/or exchange of the debt securities; |

| • |     | the provision for any sinking fund; |

| • |     | any restrictive covenants; |

| • |     | events of default; |

| • |     | whether the series of debt securities are issuable in definitive or global form or in definitive form only upon 
 satisfaction of certain conditions;                                                                             |

| • |     | any provisions for legal defeasance or covenant defeasance; |

| • |     | whether and under what circumstances we will pay additional amounts in respect of any tax, assessment or                                                             
 governmental charge and, if so, whether we will have the option to redeem the debt securities rather than pay the additional amounts (and the terms of this option); |

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| • |     | any provisions for convertibility or exchangeability of the debt securities into or for any other securities; |

| • |     | any listing of the debt securities on any securities exchange; |

| • |     | any paying agents, authenticating agents, security registrars or other agents for debt securities, if other than 
 the trustee;                                                                                                     |

| • |     | any provisions relating to any security provided for the debt securities, including any provisions regarding the 
 circumstances under which collateral may be released or substituted;                                             |

| • |     | if applicable, a discussion of certain U.S. federal income tax considerations, including those related to 
 original issue discount, if applicable; and                                                               |

| • |     | any other material terms. |

Unless the prospectus supplement states otherwise, principal, interest and premium, if any, will be paid by us in immediately available funds. General Any debt securities we issue will be governed by a document called an “indenture,” the form of which is filed as an exhibit to the registration statement of which this prospectus forms a part. An indenture is a contract between us and a financial institution acting as trustee on behalf of the holders of the debt securities, and is subject to and governed by the Trust Indenture Act of 1939. The trustee has two main roles. First, the trustee can enforce holders’ rights against us if we default. There are some limitations on the extent to which the trustee acts on holders’ behalf, described in the second paragraph under “Description of Debt Securities—Events of Default.” Second, the trustee performs certain administrative duties, such as sending