Company: AGIO
Filing Date: 2025-04-25
Form Type: DEF 14A
Source: 0001193125-25-096719
Chunk: 97

Company: AGIOS PHARMACEUTICALS, INC.
Filing Date: 2025-04-25
Form: DEF 14A
Chunk 97
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 exclusions and inclusions of certain amounts for the PEOs and theNon-PEONEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column for PEO 2 and thenon-PEONEOs are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table. |

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| Year |     | SummaryCompensationTable Total forPEO 2($) |           |     | Exclusion of StockAwards andOption Awards forPEO 2($) |            |   |     | Inclusion of EquityValues forPEO 2($) |            |     | CompensationActually Paid toPEO 2($) |            |
| 2024 |     |                                            | 6,776,359 |     |                                                       | (5,223,086 | ) |     |                                       | 11,420,002 |     |                                      | 12,973,276 |

| Year |     | AverageSummaryCompensationTable Total forNon-PEO NEOs($) |           |     | Average Exclusionof Stock Awardsand OptionAwards forNon-PEONEOs($) |            |   |     | Average Inclusionof Equity ValuesforNon-PEONEOs($) |           |     | AverageCompensationActually PaidtoNon-PEONEOs($) |           |
| 2024 |     |                                                          | 2,462,405 |     |                                                                    | (1,616,775 | ) |     |                                                    | 2,681,106 |     |                                                  | 3,526,736 |

The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables:

| Year |     | Year-End FairValue of EquityAwards GrantedDuring YearThat RemainedUnvested as ofLast Day ofYear forPEO 2($) |           |     | Change in FairValue from LastDay of Prior Yearto Last Day of Yearof UnvestedEquity AwardsGranted in anyPrior Year forPEO 2($) |           |     | Vesting-Date FairValue of EquityAwards GrantedDuring Year thatVested DuringYear forPEO 2($) |   |     | Change in Fair Valuefrom Last Day ofPrior Year to VestingDate of UnvestedEquity AwardsGranted in any PriorYear that VestedDuring Year for