Company: RNAC
Filing Date: 2025-04-28
Form Type: DEF 14A
Source: 0001453687-25-000075
Chunk: 1

Company: Cartesian Therapeutics, Inc.
Filing Date: 2025-04-28
Form: DEF 14A
Chunk 1
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 Stockholders and Proxy Statement on the following pages describe the matters to be presented at the Annual Meeting. Details regarding how to attend the meeting online and the business to be conducted at the Annual Meeting are more fully described in the Notice of Annual Meeting of Stockholders and Proxy Statement. Please see the section called “Who Can Attend the 2025 Annual Meeting?” on page 4 of the Proxy Statement for more information.

Whether or not you attend the Annual Meeting, it is important that your shares be represented and voted at the Annual Meeting. Therefore, I urge you to promptly vote and submit your proxy by phone, via the Internet, or, if you received paper copies of these materials, by signing, dating and returning the enclosed proxy card in the enclosed envelope, which requires no postage if mailed in the United States. If you have previously received our Notice of Internet Availability of Proxy Materials, then instructions regarding how you can vote are contained in that notice. If you have received a proxy card, then instructions regarding how you can vote are contained on the proxy card. If you decide to attend the virtual Annual Meeting, you will be able to vote your shares electronically, even if you have previously submitted your proxy.

On behalf of the Board of Directors, thank you for your continued support and investment in Cartesian Therapeutics, Inc.

This proxy statement is dated April 28, 2025 and is first being mailed to stockholders on or about April 28, 2025.

| Sincerely,                                      |
| /s/ Carsten Brunn, Ph.D.                        |
| Carsten Brunn, Ph.D.                            |
| President and Chief Executive Officer, Director |

#### Table of Contents
|                                                                                             |     |    |     | Page |
| Notice of 2025 Annual Meeting of Stockholders                                               |     |  1 |     |      |
| Proxy Statement                                                                             |     |  2 |     |      |
| Questions and Answers About the 2025Annual Meeting of Stockholders                          |     |  4 |     |      |
| Proposal No. 1 Election of Directors                                                        |     |  7 |     |      |
| Proposal No. 2 Non-Binding, Advisory Approval of Compensation of Named Executive Officers   |     | 11 |     |      |
| Proposal No. 3 Ratification of Appointment of Independent Registered Public Accounting Firm |     | 12 |     |      |
| Report of the Audit Committee of the Board                                                  |     | 13 |     |      |