Company: MTB-PJ
Filing Date: 2025-10-30
Form Type: 424B5
Source: 0001193125-25-257002
Chunk: 70

Company: M&T BANK CORP
Filing Date: 2025-10-30
Form: 424B5
Chunk 70
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 • |     | changes in interest rates, spreads on earning assets and interest-bearing liabilities, and interest rate 
 sensitivity;                                                                                             |

| • |     | prepayment speeds, loan originations, credit losses and market values on loans, collateral securing loans and 
 other assets;                                                                                                 |

| • |     | sources of liquidity; |

| • |     | common shares outstanding; |

| • |     | common stock price volatility; |

| • |     | fair value of and number of stock-based compensation awards to be issued in future periods; |

| • |     | the impact of changes in market values on trust-related revenues; |

| • |     | regulatory supervision and oversight, including monetary policy and capital requirements; |

| • |     | domestic or international political developments and other geopolitical events, including international 
 conflicts;                                                                                              |

| • |     | governmental and public policy changes, including tax policy; |

| • |     | the outcome of pending and future litigation and governmental proceedings, including tax-related examinations and other matters; |

2

| • |     | changes in accounting policies or procedures as may be required by the Financial Accounting Standards Board, 
 regulatory agencies or legislation;                                                                          |

| • |     | increasing price, product and service competition by competitors, including new entrants; |

| • |     | rapid technological developments and changes; |

| • |     | the ability to continue to introduce competitive new products and services on a timely, cost-effective basis; |

| • |     | the mix of products/services; |

| • |     | containing costs and expenses; |

| • |     | protection and validity of intellectual property rights; |

| • |     | reliance on large customers; |

| • |     | technological, implementation and cost/financial risks in large, multi-year contracts; |

| • |     | continued availability of financing; |

| • |     | financial resources in the amounts, at the times and on the terms required to support M&T and its 
 subsidiaries’ future businesses; and                                                              |

| • |     | material differences in the actual financial results of merger, acquisition and investment activities compared        
 with M&T’s initial expectations, including the full realization of anticipated cost savings and revenue enhancements. |

In addition, Future Factors related to the acquisition of People’s United include, among others: the possibility that the anticipated benefits of the transaction will not be realized when expected or at all; potential adverse reactions or changes to business, customer or employee relationships; M&T’s success