Company: CL
Filing Date: 2025-11-03
Form Type: 424B2
Source: 0001104659-25-105106
Chunk: 10

Company: COLGATE PALMOLIVE CO
Filing Date: 2025-11-03
Form: 424B2
Chunk 10
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 Notes at any time.                                                                                                                                                                                                                                                                                                                                                                                                                                               |
| Trustee                       | The Bank of New York Mellon                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |
| London Paying Agent           | The Bank of New York Mellon, London Branch                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            |
| Book-Entry                    | The Notes will be issued in book-entry form and will be represented by global Notes deposited with, or on behalf of, a common depositary on behalf of Clearstream and Euroclear  and registered in the name of the common depositary or its nominee. Beneficial interests in any of the Notes will be shown on, and transfers will be effected only through, records maintained by Clearstream and Euroclear and their participants, and these beneficial interests may not be exchanged for certificated Notes, except in limited circumstances. See “Description of the Notes—Book-Entry Delivery and Settlement.”                                                                  |
| Risk Factors                  | See “Risk Factors” and the other information included in or incorporated by reference into this prospectus supplement and the accompanying prospectus for a discussion of factors you should carefully consider before deciding to purchase the Notes.                                                                                                                                                                                                                                                                                                                                                                                                                                |
| Governing Law                 | New York                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              |

<div align='center'>S-3

Risk Factors</div>

Your investment in the Notes involves certain risks. In consultation with your own financial, tax, accounting and legal advisers, you should carefully consider, among other matters, the factors set forth below as well as the risk factors discussed in the accompanying prospectus and in our most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q, which are incorporated by reference into this prospectus supplement and the accompanying prospectus before deciding whether to make an investment in the Notes.

Risks Related to the Notes

Our indebtedness could materially and adversely affect our ability to meet our debt service obligations under the Notes.

As of September 30, 2025, we had $8,419 million
of indebtedness outstanding on a consolidated basis. Of such indebtedness, approximately $68 million was indebtedness of our subsidiaries.
In addition, we have a $3,000 million revolving credit facility. At September 30, 2025, we had no outstanding borrowings under the
revolving credit facility.

Our level of indebtedness and the limitations imposed
on us by our debt agreements could have significant adverse consequences to holders of the Notes. Our cash flow may be insufficient to
meet our debt service obligations with respect to the Notes and our other indebtedness, which