Company: HURA
Filing Date: 2025-11-03
Form Type: S-3
Source: 0001193125-25-262843
Chunk: 17

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-11-03
Form: S-3
Chunk 17
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 filed with the SEC as an exhibit to:

| • |     | a post-effective amendment to the registration statement of which this prospectus is a part; |

| • |     | an annual report on Form 10-K; |

| • |     | a quarterly report on Form 10-Q; or |

| • |     | a current report on Form 8-K. |

Defeasance and Covenant Defeasance When we use the term defeasance, we mean discharge from some or all of our obligations under an indenture. If we deposit with the trustee sufficient cash or government obligations to pay the principal, interest, any premium and any mandatory sinking fund or analogous payments due to the stated maturity or a redemption date of the debt securities of a particular series, then at our option:

| • |     | we will be discharged from our obligations for the debt securities of that series, the holders of the debt 
 securities of the affected series will no longer be entitled to the benefits of the indenture, except for  |

10

| registration of transfer and exchange of debt securities and replacement of lost, stolen or mutilated debt securities, and those holders may look only to the deposited funds or obligations for 
 payment, which is referred to as “defeasance”; or                                                                                                                                                |

| • |     | we will no longer be under any obligation to comply with certain covenants under the applicable indenture as it               
 relates to that series, and some events of default will no longer apply to us, which is referred to as “covenant defeasance.” |

Unless the applicable prospectus supplement specifies otherwise and except as described below, the conditions to both defeasance and covenant defeasance are as follows:

| • |     | it must not result in a breach or violation of, or constitute a default or event of default under, the applicable                     
 indenture, or result in a breach or violation of, or constitute a default under, any other of our material agreements or instruments; |

| • |     | certain bankruptcy-related defaults or events of default with respect to us must not have occurred and be                                                       
 occurring during the period commencing on the date of the deposit of the trust funds to defease the debt securities and ending on the 91st day after that date; |

| • |     | we must deliver to the trustee an officer’s certificate and an opinion of counsel addressing compliance 
 with the conditions of the defeasance or covenant defeasance; and                                       |

| •