Company: RNLXY
Filing Date: 2025-09-04
Form Type: F-6 POS
Source: 0001193805-25-001256
Chunk: 4

Company: Renalytix plc
Filing Date: 2025-09-04
Form: F-6 POS
Chunk 4
---
 for filing on
Form F-6 are met and has duly caused this Post-Effective Amendment No. 1 to Registration Statement on Form F-6 to be signed on its behalf
by the undersigned, thereunto duly authorized, in the City of New York, State of New York, on the 4th day of September,
2025.

| Legal entity created by the Deposit Agreement, as amended, under which the American Depositary Shares registered hereunder are to be issued, each American Depositary Share representing the right to receive two (2) ordinary shares of Renalytix plc. |                            |
| CITIBANK, N.A., solely in its capacity as Depositary                                                                                                                                                                                                    |                            |
| By:                                                                                                                                                                                                                                                     | /s/ Leslie DeLuca          |
|                                                                                                                                                                                                                                                         | Name:  Leslie DeLuca       |
|                                                                                                                                                                                                                                                         | Title:    Attorney-in-fact |

<div align='center'>II-3</div>

Pursuant to the requirements
of the Securities Act of 1933, as amended, Renalytix plc certifies that it has reasonable grounds to believe that all the requirements
for filing on Form F-6 are met and has duly caused this Post-Effective Amendment No. 1 to Registration Statement on Form F-6 to be signed
on its behalf by the undersigned thereunto duly authorized, in Salt Lake City, Utah, on August 25, 2025.

| Renalytix plc |                                   |
| By:           | /s/ James McCullough              |
|               | Name:  James McCullough           |
|               | Title:    Chief Executive Officer |

<div align='center'>II-4</div>

KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints each of James McCullough and Joel Jung to act as
his/her true and lawful attorney-in-fact and agent, with full power of substitution, for him/her and in his/her name, place and stead,
in any and all such capacities, to sign any and all amendments, including post-effective amendments, and supplements to this Registration
Statement, and to file the same, with all exhibits thereto and other documents in connection therewith, with the United States Securities
and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and
thing requisite and necessary to be done in and about the premises