Company: SHPH
Filing Date: 2025-08-05
Form Type: S-1
Source: 0001641172-25-022101
Chunk: 18

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-08-05
Form: S-1
Chunk 18
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 2025)                                                                                                                                                                                              |
| 10.71  |     | Consulting Agreement, dated April 3, 2025 (incorporated by reference to 8-K filed April 4, 2025)                                                                                                                                                                                                         |

| 14 |

| 10.74 
 10.75 |     | Securities Purchase Agreement, dated June 20, 2025 (incorporated by reference to 8-K filed June 25, 2025)                 
 Registration Rights Agreement, dated June 20, 2025 2025 (incorporated by reference to 8-K filed June 25, 2025)            |
|:------|:----|:--------------------------------------------------------------------------------------------------------------------------|
| 21    |     | List of Subsidiaries (incorporated by reference to Exhibit 21 to the Annual Report on Form 10-K filed on March 21, 2024). |
| 23.1* |     | Consent of Forvis Mazars, LLP                                                                                             |
| 23.2* |     | Consent of Sichenzia Ross Ference Carmel LLP (included in Exhibit 5.1)                                                    |
| 24    |     | Power of Attorney (included in the signature page to this registration statement).                                        |
| 107*  |     | Filing Fee Table                                                                                                          |

+Certain portions of this exhibit have been redacted in accordance with Item 601(b)(10)(iv) because such information (i) is deemed not material and (ii) is of the type of information that the Company normally treats as private or confidential.

* Filed herewith

(b) Financial statement schedules

Schedules not listed above have been omitted because the information required to be set forth therein is not applicable or is shown in the financial statements or notes thereto.

Item 17. Undertakings

The undersigned registrant hereby undertakes:

(1) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

(i) To include any prospectus required by Section 10(a)(3) of the Securities Act;

(ii) To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of