Company: TVRD
Filing Date: 2025-05-30
Form Type: S-1
Source: 0001104659-25-054853
Chunk: 0

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-05-30
Form: S-1
Chunk 0
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As filed with the Securities and Exchange Commission on May 30, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT Under The Securities Act of 1933 TVARDI THERAPEUTICS, INC. (Exact name of Registrant as specified in its charter)

| Delaware                        |     |                         2834 |     | 75-3175693            |
| (State or other jurisdiction of 
 incorporation or organization)  |     | -Primary Standard Industrial 
   Classification Code Number |     | -I.R.S. Employer      
 Identification Number |

3 Sugar Creek Ctr. Blvd. Suite 525 Sugar Land, TX 77478 (713) 489-8654 (Address, including zip code, and telephone number, including area code, of Registrant’s principal executive offices) Imran Alibhai Chief Executive Officer 3 Sugar Creek Ctr. Blvd. Suite 525 Sugar Land, TX 77478 (713) 489-8654 (Name, address, including zip code, and telephone number, including area code, of agent for service) Copies to: Divakar Gupta Madison A. Jones Cooley LLP 55 Hudson Yards New York, NY 10001 (212) 479-6000 Approximate date of commencement of proposed sale to the public: As soon as practicable after this registration statement becomes effective. If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933 check the following box: ☒ If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐ If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐ If this Form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated fil