Company: SCLXW
Filing Date: 2025-10-31
Form Type: 424B3
Source: 0001193125-25-259839
Chunk: 3

Company: Scilex Holding Co
Filing Date: 2025-10-31
Form: 424B3
Chunk 3
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 or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☒

Item 1.02. Termination of a Material Definitive Agreement. Equity Line of Credit As previously disclosed, Scilex Holding Company (the “Company”) entered into a Common Stock Purchase Agreement and Registration Rights Agreement (the “Original Agreements”) on July 22, 2025 with Tumim Stone Capital, LLC (“Tumim”) as part of an equity line of credit (the “ELOC”). Pursuant to the Original Agreements, the Company was obligated to issue 150,000 shares of the Company’s common stock (the “Commitment Shares”) to Tumim upon effectiveness of the registration statement related to the ELOC. On October 30, 2025 the Company and Tumim entered into a Termination Agreement pursuant to which each of the Original Agreements shall terminate upon payment in full of an aggregate of $2.7 million by the Company to Tumim in lieu of the issuance of the Commitment Shares with $500,000 to be paid on or before each of October 31, 2025 and November 14, 2025 and the remaining $1.7 million to be paid on or before December 15, 2025. The Company acknowledges Tumim’s beneficial support. The termination of the Original Agreements is due to the Company no longer needing to raise additional capital under the Original Agreements at this time. Item 9.01. Financial Statements and Exhibits. (d) Exhibits.

| Exhibit 
 Number  
 10.1    | Description                                                                                                        
 Termination Agreement, dated October 30, 2025, by and between Scilex Holding Company and Tumim Stone Capital, LLC. |
|:--------|:-------------------------------------------------------------------------------------------------------------------|
| 104     | Cover Page Interactive Data File, formatted in Inline Extensible Business Reporting Language (iXBRL).              |

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SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

|                        | SCILEX HOLDING COMPANY |                                     |
|                        | By:                    | /s/ Henry Ji                        |
|                        | Name:                  | Henry Ji                            |
| Date: October 31, 2025 | Title:                 | Chief Executive Officer & President |

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