Company: PFSA
Filing Date: 2025-04-28
Form Type: S-4/A
Source: 0001213900-25-035718
Chunk: 788

Company: Profusa, Inc.
Filing Date: 2025-04-28
Form: S-4/A
Chunk 788
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| By:                         |     | /s/ Fred Knechtel |     |                    |
|                             |     | Name:             |     | Fred Knechtel      |
|                             |     | Title:            |     | CFO and Co-Founder |

| Merger Sub:                 |     |                   |     |               |
| NV PROFUSA MERGER SUB, INC. |     |                   |     |               |
| By:                         |     | /s/ Fred Knechtel |     |               |
|                             |     | Name:             |     | Fred Knechtel |
|                             |     | Title:            |     | Officer       |

[SIGNATURE PAGE TO AMENDMENT TO MERGER AGREEMENT]

Annex A-3-2

IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be duly executed as of the day and year first above written.

| Company:      |     |               |     |           |
| PROFUSA, INC. |     |               |     |           |
| By:           |     | /s/ Ben Hwang |     |           |
|               |     | Name:         |     | Ben Hwang |
|               |     | Title:        |     | CEO       |

[SIGNATURE PAGE TO AMENDMENT TO MERGER AGREEMENT]

Annex A-3-3 ANNEX A-4 AMENDMENT NO. 4 TO MERGER AGREEMENT AND PLAN OF REORGANIZATION February 11, 2025 THIS AMENDMENT No. 4 to the Merger Agreement and Plan of Reorganization, dated as of November 7, 2022 (as amended by Amendment No. 1 to the Merger Agreement and Plan of Reorganization, dated September 12, 2023, by Amendment No. 2 to the Merger Agreement and Plan of Reorganization, dated January 12, 2024, by Amendment No. 3, dated March 4, 2024, and as may be further amended, restated, supplemented or otherwise modified from time to time in accordance with its terms, the “ Merger Agreement ”), by and among NorthView Acquisition Corp., a Delaware corporation (“ Parent ”), NV Profusa Merger Sub, Inc., a Delaware corporation and a direct, wholly owned subsidiary of Parent (“ Merger Sub ”), and Profusa, Inc., a California corporation (the “ Company ”), is effective as of the