Company: GLPG
Filing Date: 2025-12-10
Form Type: S-8
Source: 0001104659-25-119980
Chunk: 0

Company: GALAPAGOS NV
Filing Date: 2025-12-10
Form: S-8
Chunk 0
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<div align='center'>As filed with the U.S. Securities and Exchange Commission on December 10, 2025</div>

Registration No. 333-

<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM S-8

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

GALAPAGOS NV

(Exact name of registrant as specified in its charter)</div>

| Belgium                         |     | Not applicable        |
| (State or other jurisdiction of 
 incorporation or organization)  |     | -I.R.S. Employer      
 Identification Number |

<div align='center'>Generaal De Wittelaan L11 A3

2800 Mechelen, Belgium

+32 15 342 900

(Address, including zip code, and telephone number, including area code, of registrant’s principal executive offices)

Subscription Right Plan 2025 (A)

Subscription Right Plan 2025 (B)

(Full title of the plan)

C T Corporation System

28 Liberty Street

New York, New York 10005

(212) 590-9070

(Name, address, including zip code, and telephone number, including area code, of agent for service)

Copies to:

Michael H. Bison, Esq.

Janet Hsueh

Goodwin Procter LLP

100 Northern Avenue

Boston, MA 02210

(617) 570-1000</div>

Indicate by check mark whether the registrant is a large accelerated
filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of
“large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth
company” in Rule 12b-2 of the Exchange Act.

| Large accelerated filer | x |     | Accelerated filer         | ¨ |
| Non-accelerated filer   | ¨ |     | Smaller reporting company | ¨ |
|                         |   |     | Emerging Growth Company   | ¨ |

If an emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant
to Section 7(a)(2)(B) of the Securities Act. ¨

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