Company: TEM
Filing Date: 2025-08-08
Form Type: S-3ASR
Source: 0001193125-25-175993
Chunk: 30

Company: Tempus AI, Inc.
Filing Date: 2025-08-08
Form: S-3ASR
Chunk 30
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, or reducing any 
 premium payable upon the redemption of any series of any debt securities; or                                      |

| • |     | reducing the percentage of debt securities, the holders of which are required to consent to any amendment, 
 supplement, modification or waiver.                                                                        |

Discharge Each indenture provides that we can elect to be discharged from our obligations with respect to one or more series of debt securities, except for specified obligations, including obligations to:

| • |     | provide for payment; |

| • |     | register the transfer or exchange of debt securities of the series; |

| • |     | replace stolen, lost or mutilated debt securities of the series; |

| • |     | pay principal of and premium and interest on any debt securities of the series; |

| • |     | maintain paying agencies; |

| • |     | hold monies for payment in trust; |

| • |     | recover excess money held by the trustee; |

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| • |     | compensate and indemnify the trustee; and |

| • |     | appoint any successor trustee. |

In order to exercise our rights to be discharged, we must deposit with the trustee money or government obligations sufficient to pay all the principal of, any premium, if any, and interest on, the debt securities of the series on the dates payments are due. Form, Exchange and Transfer We will issue the debt securities of each series only in fully registered form without coupons and, unless we provide otherwise in the applicable prospectus supplement, in denominations of $1,000 and any integral multiple thereof. The indenture provides that we may issue debt securities of a series in temporary or permanent global form and as book-entry securities that will be deposited with, or on behalf of, The Depository Trust Company (“DTC”) or another depositary named by us and identified in the applicable prospectus supplement with respect to that series. To the extent the debt securities of a series are issued in global form and as book-entry, a description of terms relating to any book-entry securities will be set forth in the applicable prospectus supplement. At the option of the holder, subject to the terms of the indenture and the limitations applicable to global securities described in the applicable prospectus supplement, the holder of the debt securities of any series can exchange the debt securities for other debt securities of the same series, in any authorized denomination and of like tenor and aggregate principal amount. Subject to the terms of the indenture and the limitations applicable to global securities set forth in