Company: QTIWW
Filing Date: 2025-12-31
Form Type: 424B3
Source: 0001628280-25-059235
Chunk: 5

Company: QT IMAGING HOLDINGS, INC.
Filing Date: 2025-12-31
Form: 424B3
Chunk 5
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 predicted. Accordingly, the adverse market and price pressures resulting from an offering pursuant to the registration statement may continue for an extended period of time.

You should read this prospectus and any prospectus supplement of amendment carefully before you invest in our securities. Our Common Stock are traded in the over-the-counter (OTC) Market OTCQB under the symbol “QTIH,” and our Public Warrants are traded in the OTC market under the symbol “QTIWW.” On December 26, 2025, the closing price of our Common Stock was $5.95, and on December 26, 2025, the closing price for our Public Warrants was $0.114.

We are an “emerging growth company” as defined in Section 2(a) of the Securities Act of 1933, as amended, and are subject to reduced public company reporting requirements. This prospectus complies with the requirements that apply to an issuer that is an emerging growth company.

#### See the section entitled “

#### Risk Factors

#### ” beginning on page

#### 17
of this prospectus to read about factors you should consider before buying our securities.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

#### The date of this prospectus is December 31, 2025.
You should rely only on the information provided in this prospectus, as well as the information incorporated by reference into this prospectus and any applicable prospectus supplement. Neither we nor the Selling Securityholders have authorized anyone to provide you with different information. Neither we nor the Selling Securityholders are making an offer of these securities in any jurisdiction where the offer is not permitted. You should not assume that the information in this prospectus or any applicable prospectus supplement is accurate as of any date other than the date of the applicable document. Since the date of this prospectus and the documents incorporated by reference into this prospectus, our business, financial condition, results of operations and prospects may have changed.

### TABLE OF CONTENTS
|                                                                                       |     | Page |
| ABOUT THIS PROSPECTUS                                                                 |     |    1 |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS                                  |     |    2 |
| PROSPECTUS SUMMARY                                                                    |     |    4 |
| RISK FACTORS                                                                          |     |   17 |
| USE OF PRO