Company: GHRS
Filing Date: 2025-02-06
Form Type: 6-K
Source: 0000950103-25-001704
Chunk: 1

Company: GH Research PLC
Filing Date: 2025-02-06
Form: 6-K
Chunk 1
---
to the offer and sale of the ordinary shares. Opinion of counsel regarding the validity of the ordinary shares is attached to this Report
on Form 6-K as Exhibit 5.1 and the consent of such counsel relating to the incorporation of such opinion into the Registration Statement
is attached to this Report on Form 6-K as Exhibit 23.1.

The proceeds from the offer and sale of the ordinary shares are estimated
to be approximately $139.8 million, after deducting the underwriting discounts and commissions and estimated offering expenses payable
by the Company. The Company intends to use the net proceeds from the offer and sale of the ordinary shares to strategically invest in
research, clinical and technical development of current and/or additional product candidates, working capital, capital expenditures and
general corporate purposes.

<div align='center'>1

INCORPORATION BY REFERENCE</div>

This Report on Form 6-K, including Exhibits 1.1,
5.1 and 23.1, shall be deemed to be incorporated by reference into the registration statement on Form S-8 (Registration No. 333-270422)
and the registration statement on Form F-3 (Registration No 333-270418) of the Company and to be a part thereof from the date on which
this report is filed, to the extent not superseded by documents or reports subsequently filed or furnished.

<div align='center'>2</div>

EXHIBIT INDEX

| Exhibit No. 
 1.1         | Description                                                                                                                                                                                      
 Underwriting Agreement, dated February 4, 2025, between GH Research PLC and Cantor Fitzgerald & Co. and Stifel, Nicolaus & Company, Incorporated, as representatives of the several underwriters |
|:------------|:-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 5.1         | Opinion of A&L Goodbody LLP, Irish counsel of GH Research PLC                                                                                                                                    |
| 23.1        | Consent of A&L Goodbody LLP (included in exhibit 5.1)                                                                                                                                            |

<div align='center'>3

SIGNATURE</div>

Pursuant to the requirements of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

| Date: February 6, 2025 | GH Research PLC |                         |
|:-----------------------|:----------------|:------------------------|
|                        | By:             | /s/ Julie