Company: CNTB
Filing Date: 2025-03-31
Form Type: 10-K
Source: 0001835268-25-000014
Chunk: 179

Company: Connect Biopharma Holdings Ltd
Filing Date: 2025-03-31
Form: 10-K
Item: Item 1A
Chunk 179
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72

•changes in the structure of healthcare payment systems, especially in light of current reforms to the U.S. healthcare system; 

•the success or failure of our efforts to acquire, license or develop additional Product Candidates; 

•innovations or new products developed by us or our competitors; 

•announcements by us or our competitors of significant acquisitions, strategic partnerships, joint ventures or capital commitments;

•manufacturing, supply or distribution delays or shortages; 

•any changes to our relationship with any manufacturers, suppliers, licensors, future collaborators or other strategic partners; 

•achievement of expected product sales and profitability; 

•variations in our financial results or those of companies that are perceived to be similar to us; 

•market conditions in the biopharmaceutical sector and issuance of securities analysts’ reports or recommendations; 

•trading volume of our ADSs; 

•an inability to obtain additional funding; 

•sales of our securities by insiders and shareholders;

•general economic, industry and market conditions other events or factors, many of which are beyond our control;

•additions or departures of key personnel;

•the changing global political environment and military actions and their effect on the economy and financial market; and

•intellectual property, product liability or other litigation against us.

In addition, in the past, shareholders have initiated class action lawsuits against biopharmaceutical companies following periods of volatility in the market prices of these companies’ shares. Such litigation, if instituted against us, could cause us to incur substantial costs and divert management’s attention and resources, which could have a material adverse effect on our business, financial condition and results of operations.

Unstable market and economic conditions may have serious adverse consequences on our business, financial condition and results of operations and the price of our ADSs.

From time to time, the global credit and financial markets have experienced extreme volatility and disruptions, including severely diminished liquidity and credit availability, declines in consumer confidence, declines in economic growth, increases in unemployment rates and uncertainty about economic stability. There can be no assurance that future deterioration in credit and financial markets and confidence in economic conditions will not occur. Our business strategy and performance may be adversely affected by any such economic downturn, volatile business environment or continued unpredictable and unstable market conditions. The financial markets and the global economy may also be adversely affected by the current or anticipated impact of military conflict, including the Russia-Ukraine war and terrorism or other geopolitical events. Sanctions imposed by the U.S. and other countries in response to such conflicts, including