Company: SHPH
Filing Date: 2025-03-31
Form Type: DEF 14A
Source: 0001641172-25-001889
Chunk: 4

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-03-31
Form: DEF 14A
Chunk 4
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 TO 1-FOR-10 (THE “REVERSE STOCK SPLIT”).

The Board of Directors recommends that you vote FOR authorization of the Board of Directors to amend the Company’s amended and restated certificate of incorporation to effect a reverse stock split of all of the Company’s issued and outstanding common stock by a ratio in the range of 1-for-3 to 1-for-10. We believe that conducting the Reverse Stock Split is in the best interest of the Company and its stockholders.

PROPOSAL NO. 5: APPROVAL OF THE FIRST AMENDMENT TO THE SHUTTLE PHARMACEUTICALS HOLDINGS, INC. 2018 EQUITY INCENTIVE PLAN TO INCREASE THE AMOUNT OF SHARES RESERVED FOR ISSUANCE BY 5,000,000 SHARES OF COMMON STOCK.

The Board of Directors recommends that you vote FOR the first amendment
to the Shuttle Pharmaceuticals Holdings, Inc. 2018 Equity Incentive Plan to increase the amount of shares reserved for issuance by 5,000,000
shares of common stock. We believe that increase the number of shares reserved under the Company’s 2018 Equity Incentive Plan is
in the best interest of the Company and its stockholders.

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introduction to our Board of Directors

|                                        |     |     |     |              |     | Committee   
 Memberships |     |              |     |            |
| Name                                   
 and Position                           |     | Age |     | Other        
 Public Board 
 Memberships  |     | Audit       |     | Compensation |     | Nominating 
 &          
 Corporate  
 Governance |
| ANATOLY                                
 DRITSCHILO, MD                         
 CHIEF SCIENTIFIC OFFICER AND  CHAIRMAN |     |  80 |     |              |     |             |     |              |     |            |
| STEVEN                                 
 RICHARDS                               
 INDEPENDENT                            
 DIRECTOR                               |     |  56 |     |              |     | C           |     | M            |     |            |
| GEORGE                                 
 SCORSIS                                
 INDEPENDENT                            
 DIRECTOR                               |     |  48 |     |              |     | M           |     | C            |     | M          |
| OLEH                                   
 NABYT                                  
 INDEPENDENT                            
 DIRECTOR                               |     |  31 |     |              |     | M           |     | M            |