Company: HURA
Filing Date: 2025-06-06
Form Type: 425
Source: 0001193125-25-137145
Chunk: 6

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-06-06
Form: 425
Chunk 6
---
 securities laws. Nothing herein shall constitute an offer to sell or the solicitation of an offer to buy any securities. Item 3.02 Unregistered Sales of Equity Securities. The information set forth under Item 1.01 is incorporated by reference into this Item 3.02. Item 7.01 Regulation FD Disclosure. On June 3, 2025, the Company issued a press release announcing the Offering, a copy of which is filed herewith as Exhibit 99.1 and is incorporated by reference. Subsequent to the issuance of the press release, the size and amount of the Offering were slightly adjusted, with the final offering and size amount disclosed above in this Form 8-K. The disclosure in this Item 7.01 (including the exhibit) shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934 (the “Exchange Act”), or otherwise subject to the liabilities of Section 18 of the Exchange Act, nor shall it be deemed incorporated by reference in any of the Company’s filings under the Securities Act or the Exchange Act, except to the extent, if any, expressly set forth by specific reference in such filing. Item 9.01 Financial Statements and Exhibits. (d) Exhibits

| Exhibit No |     |                                                                             |
| 4.1        |     | Form of Warrant.                                                            |
| 10.1       |     | Form of Securities Purchase Agreement.                                      |
| 99.1       |     | Press Release, dated June 3, 2025                                           |
| 104        |     | Cover Page Interactive Data File (embedded within the inline XBRL document) |

SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

| Date: June 6, 2025 |     | By: |     | TUHURA BIOSCIENCES, INC.        
 /s/ Dan Dearborn                |
|:-------------------|:----|:----|:----|:--------------------------------|
|                    |     |     |     | Name: Dan Dearborn              |
|                    |     |     |     | Title:  Chief Financial Officer |

Exhibit 4.1

THIS WARRANT AND THE SHARES OF COMMON STOCK ISSUABLE UPON THE EXERCISE OF THIS WARRANT (THE “SECURITIES”) HAVE NOT BEEN REGISTERED UNDER