Company: CSTL
Filing Date: 2025-03-28
Form Type: PRE 14A
Source: 0001447362-25-000050
Chunk: 13

Company: CASTLE BIOSCIENCES INC
Filing Date: 2025-03-28
Form: PRE 14A
Chunk 13
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     | ●               |     | ●                 |
| Financial Analysis & Control Experience          |     |                |     | ●                 |     | ●                |     | ●                         |     | ●             |     | ●                  |     | ●               |     | ●                 |
| Digital Health                                   |     | ●              |     |                   |     | ●                |     |                           |     | ●             |     |                    |     | ●               |     | ●                 |
| Health System (HE) Experience                    |     |                |     |                   |     | ●                |     |                           |     | ●             |     | ●                  |     |                 |     | ●                 |
| R&D Scientific Leadership                        |     |                |     |                   |     |                  |     | ●                         |     |               |     | ●                  |     |                 |     | ●                 |
| Regulatory/Lab Services Reimbursement            |     | ●              |     |                   |     |                  |     | ●                         |     | ●             |     | ●                  |     | ●               |     | ●                 |
| Diversity of Skills, Background, and Perspective |     | ●              |     |                   |     | ●                |     |                           |     | ●             |     | ●                  |     |                 |     | ●                 |
| Cybersecurity                                    |     |                |     |                   |     |                  |     |                           |     |               |     |                    |     | ●               |     | ●                 |

(1) Our Board Qualification and Attributes Matrix is reviewed and updated annually to reflect evolving strategic priorities and the reassessment of key board skills.

#### Castle Biosciences 2025 Proxy Statement19
| Information Regarding the Board of Directors and Corporate Governance |

### DIRECTOR TIME COMMITMENT
Our Board seeks candidates who it believes will be able to devote sufficient time and attention to serve as a director, taking into account each candidate’s principal occupation, service on other boards of directors, and, for incumbent directors who are being considered for reelection, attendance and performance at Castle’s Board and committee meetings.

Over the past year, our Nominating and Corporate Governance Committee has had ongoing discussions on the topic of director time commitments and has reviewed the policies of peers and other public companies, as well as various institutional policies. Further, as part of our stockholder outreach, we have discussed this topic with many of our investors. Based on this information, and taking into