Company: BDRX
Filing Date: 2025-11-17
Form Type: POS AM
Source: 0001214659-25-016809
Chunk: 81

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-11-17
Form: POS AM
Chunk 81
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the above options, any of the cash, securities or other property it receives will constitute part of the deposited securities and each
Depositary Share will then represent a proportionate interest in such property.

Amendment and Termination

How may the Deposit Agreement be amended?

We may agree
with the depositary to amend the Deposit Agreement and the Depositary Shares without your consent for any reason. ADR holders must be
given at least thirty (30) days’ notice of any amendment that imposes or increases any fees on a per Depositary Share basis, charges
or expenses (other than stock transfer or other taxes and other governmental charges, transfer or registration fees, a transaction fee
per cancellation request (including any cancellation request made through SWIFT, facsimile transmission or any other method of communication),
applicable delivery expenses or other such fees, charges or expenses), or otherwise prejudices any substantial existing right of ADR
holders or beneficial owners. Such notice need not describe in detail the specific amendments effectuated thereby, but must identify
to ADR holders and beneficial owners a means to access the text of such amendment. If an ADR holder or beneficial owner continues to
hold an ADR or ADRs, or an interest therein, after being so notified, such ADR holder and any beneficial owner are deemed to agree to
such amendment and to be bound by the Deposit Agreement as so amended. No amendment, however, will impair your right to surrender your
Depositary Shares and receive the underlying securities, except in order to comply with mandatory provisions of applicable law.

Any amendments
or supplements that (i) are reasonably necessary (as agreed by us and the depositary) in order for (a) the Depositary Shares to be registered
on Form F-6 under the Securities Act or (b) the Depositary Shares or Ordinary Shares to be traded solely in electronic book-entry form
and (ii) do not in either such case impose or increase any fees or charges to be borne by ADR holders, shall be deemed not to prejudice
any substantial rights of ADR holders or beneficial owners. Notwithstanding the foregoing, if any governmental body or regulatory body
should adopt new laws, rules or regulations that would require amendment or supplement of the Deposit Agreement or the form of ADR to
ensure compliance therewith, we and the depositary may amend or supplement the Deposit Agreement and the form of ADR (and all outstanding
ADRs) at any time in accordance with such changed laws, rules or regulations. Such amendment