Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 28

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 28
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 no effect on the outcome of such proposal. |

If you are a beneficial owner of Comerica common stock and you do not instruct your bank, broker or other nominee on how to vote your shares of Comerica common stock:

| • |     | Comerica merger proposal: your bank, broker or other nominee may not vote your shares on the Comerica         
 merger proposal, which broker non-votes, if any, will have the same effect as a vote “AGAINST” such proposal; |

| • |     | Comerica compensation proposal: your bank, broker or other nominee may not vote your shares on the                       
 Comerica compensation proposal, which broker non-votes, if any, will have no effect on the outcome of such proposal; and |

| • |     | Comerica adjournment proposal: your bank, broker or other nominee may not vote your shares on the Comerica 
 adjournment proposal, which broker non-votes, if any, will have no effect on the outcome of such proposal. |

| Q: | What if I fail to vote or abstain? |

| A: | For purposes of the Fifth Third special meeting, an abstention occurs when a Fifth Third voting shareholder 
 attends the Fifth Third special meeting and does not vote or returns a proxy with an “ABSTAIN” instruction. |

| • |     | Fifth Third stock issuance proposal: An abstention will have the same effect as a vote                                                                                                                                     
 “AGAINST” the Fifth Third stock issuance proposal. If a Fifth Third voting shareholder abstains or is not present at the Fifth Third special meeting and does not respond by proxy, it will have the same effect as a vote 
 “AGAINST” the Fifth Third stock issuance proposal; and                                                                                                                                                                     |

| • |     | Fifth Third adjournment proposal: An abstention will have the same effect as a vote “AGAINST”                                                                                                                              
 the Fifth Third adjournment proposal. If a Fifth Third voting shareholder is not present at the Fifth Third special meeting and does not respond by proxy, it will have no effect on the Fifth Third adjournment proposal. |

12

For purposes of the Comerica special meeting, an abstention occurs when a Comerica stockholder attends the Comerica special meeting and does not vote or returns a proxy with an “ABSTAIN” instruction.

| • |     | Comerica merger proposal: An abstention will have the same effect as a vote “AGAINST” the