Company: HURA
Filing Date: 2025-05-23
Form Type: 424B3
Source: 0001193125-25-125499
Chunk: 78

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-05-23
Form: 424B3
Chunk 78
---
, or in 
 addition to, those of Kineta stockholders generally.                                                      |

| • |     | The Merger Agreement contains provisions that could discourage a potential competing acquirer that might be 
 willing to pay more to acquire Kineta.                                                                      |

| • |     | The Mergers will involve substantial costs. |

| • |     | If Kineta does not successfully consummate the Mergers or another strategic transaction, the Kineta Board of 
 Directors may decide to pursue a dissolution and liquidation of Kineta.                                      |

| • |     | The TuHURA Bylaws designate a state court located in the State of Nevada or, if no state court located within the                                                                                                                                        
 State of Nevada has jurisdiction, the federal district court for the District of Nevada, as the exclusive forums for substantially all disputes between TuHURA and its stockholders, which will restrict the ability of stockholders of TuHURA to choose 
 the judicial forum for disputes with TuHURA or its directors, officers or employees.                                                                                                                                                                     |

| • |     | After the Mergers, Kineta stockholders will have a significantly lower ownership and voting interest in TuHURA 
 than they currently have in Kineta and will exercise less influence over management.                           |

46

Risks Relating to the Mergers

Because the Merger Consideration depends on Kineta net working capital at Closing and will not be adjusted in the event of any change in the price of either TuHURA Common Stock or Kineta Common Stock, the market value of the Merger Consideration that Kineta stockholders will receive in the Mergers is uncertain.

Upon completion of the Mergers, each share of Kineta Common Stock that is issued and outstanding immediately prior to the Closing will be
converted automatically into the right to receive, without interest, (x) the number of validly issued, fully paid and non-assessable shares of TuHURA Common Stock (rounded down to the nearest whole share
subject to the payment of any cash in lieu of fractional shares as set forth in the Merger Agreement) equal to (i) the Initial Per Share Stock Consideration plus (ii) the Delayed Per Share Stock Consideration (y) plus an amount in
cash equal to (i) the Per Share Cash Consideration plus (ii) the Disposed Asset Payment Right, all as described in “The Merger Agreement—Merger Consideration.”

Pursuant to the Merger Agreement, the amount of Kineta net