Company: SMNR
Filing Date: 2025-06-11
Form Type: S-4/A
Source: 0001193125-25-139124
Chunk: 0

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-06-11
Form: S-4/A
Chunk 0
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As filed with the U.S. Securities and Exchange Commission on June 11 , 2025 Registration No. 333-283019 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 2 to Form S-4 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Denali Capital Acquisition Corp. (Exact name of registrant as specified in its charter) For Co-Registrants,see “Table of Co-Registrants”on the following page.

| Cayman Islands*                 |     |                         6770 |     | 92-2371901            |
| (State or other jurisdiction of 
 incorporation or organization)  |     | -Primary Standard Industrial 
   Classification Code Number |     | -I.R.S. Employer      
 Identification Number |

437 Madison Avenue, 27th Floor New York, NY 10022 ( 646) 978-5180 (Address, including zip code, and telephone number, including area code, of registrant’s principal executive offices) Lei Huang Chief Executive Officer 437 Madison Avenue, 27th Floor New York, NY 10022 ( 646) 978-5180 (Name, address, including zip code, and telephone number, including area code, of agent for service) Copies to:

| Michael J. Blankenship, Esq.   
 Winston & Strawn LLP           
 800 Capital Street, Suite 2400 
 Houston, TX 77002              |     | Jeffrey T. Hartlin, Esq.   
 Elizabeth A. Razzano, Esq. 
 Paul Hastings LLP          
 1117 S. California Avenue  
 Palo Alto, CA 94304        |

Approximate date of commencement of proposed sale to the public: As soon as practicable after the effective date of this registration statement and the satisfaction or waiver of all other conditions under the Merger Agreement described herein. If the securities being registered on this Form are being offered in connection with the formation of a holding company and there is compliance with General Instruction G, check the following box: ☐ If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering: ☐ If this Form is a post-effectiveamendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number