Company: WHWK
Filing Date: 2025-03-31
Form Type: S-3
Source: 0001193125-25-068942
Chunk: 22

Company: Whitehawk Therapeutics, Inc.
Filing Date: 2025-03-31
Form: S-3
Chunk 22
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12

Relationship with Selling Stockholders

As discussed in greater detail above under the section “Prospectus Summary—Private Placement,” on December 19, 2024, we entered into
the Subscription Agreement with certain of the selling stockholders pursuant to which we sold shares of common stock to such selling stockholders, and agreed with the selling stockholders to file a registration statement to enable the resale of the
shares of common stock covered by this prospectus.

Other than (i) Bryan Ball, who is our Chief Technical Operations Officer, (ii) Anupam Dalal,
M.D., who is a member of our board of directors and the Chief Investment Officer of Acuta Capital Partners, LLC, (iii) Caley Castelein, M.D., who is the chair of our board of directors and is a Managing Director of KVP Capital GP, LLC, which is
the general partner of KVP Capital, LP., (iv) Behzad Aghazadeh, Ph.D., who is a member of our board of directors and the Managing Partner and Portfolio Manager of Avoro Capital Advisors, and (v) Baiteng Zhao, who is on our board of directors
and the Manager of WZCUBE LLC, none of the selling stockholders or any persons having control over such selling stockholders has held any position or office with us or our affiliates within the last three years or has had a material relationship
with us or any of our predecessors or affiliates within the past three years, other than as a result of the ownership of our shares or other securities.

13

Plan of Distribution The selling stockholders, which as used herein includes donees, pledgees, transferees or other successors-in-interestselling shares of common stock or interests in shares of common stock received after the date of this prospectus from a selling stockholder as a gift, pledge, partnership distribution or other transfer, may, from time to time, sell, transfer or otherwise dispose of any or all of their shares of common stock or interests in shares of common stock on any stock exchange, market or trading facility on which the shares are traded or in private transactions. These dispositions may be at fixed prices, at prevailing market prices at the time of sale, at prices related to the prevailing market price, at varying prices determined at the time of sale, or at negotiated prices. The selling stockholders may use any one or more of the following methods when disposing of shares or interests therein:

| • |     | ordinary brokerage transactions