Company: TVRD
Filing Date: 2025-02-14
Form Type: 424B3
Source: 0001104659-25-014310
Chunk: 1086

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-02-14
Form: 424B3
Chunk 1086
---
iling                      | ​ | ​ |         2.21 | ​ |
| Required Company Stockholder Vote          | ​ | ​ |          2.4 | ​ |
| Required Parent Stockholder Vote           | ​ | ​ |          3.4 | ​ |
| Response Date                              | ​ | ​ |       1.6(b) | ​ |
| Sensitive Data                             | ​ | ​ |      2.12(g) | ​ |
| Specified Parent Contracts                 | ​ | ​ |      5.12(b) | ​ |
| Stockholder Notice                         | ​ | ​ |       5.2(c) | ​ |
| Surviving Corporation                      | ​ | ​ |          1.1 | ​ |
| Tax Opinion                                | ​ | ​ |       5.1(c) | ​ |
| Third Party Expenses                       | ​ | ​ |       9.3(d) | ​ |

[ Signature pages follow ]

A-72

TABLE OF CONTENTS

#### IN WITNESS WHEREOF,
the Parties have caused this Agreement to be executed as of the date first above written.

#### CARA THERAPEUTICS, INC.
By:

/s/ Christopher Posner

Name:

Christopher Posner

Title:

President and Chief Executive Officer

#### CT CONVERGENCE MERGER SUB, INC.
By:

/s/ Christopher Posner

Name:

Christopher Posner

Title:

President and Chief Executive Officer

<div align='center'>A-73</div>

TABLE OF CONTENTS

#### IN WITNESS WHEREOF,
the Parties have caused this Agreement to be executed as of the date first above written.

#### TVARDI THERAPEUTICS, INC.
By:

/s/ Imran Alibhai, Ph.D.

Name:

Imran Alibhai, Ph.D.

Title:

Chief Executive Officer

<div align='center'>A-74</div>

TABLE OF CONTENTS

### EXHIBIT A

### CERTAIN DEFINITIONS
For purposes of this Agreement (including this Exhibit A):

“

#### Acquisition Inquiry
” means, with respect to a Party, an inquiry, indication of interest or request for information (other than an inquiry, indication of interest or request for information made or submitted by the Company or any of its Affiliates, on the one hand, or Parent or any of its Affiliates, on the other hand, to the other Party) that could reasonably be expected to lead to an Acquisition Proposal; provided, however