Company: PCRX
Filing Date: 2025-08-05
Form Type: S-8
Source: 0001396814-25-000105
Chunk: 1

Company: Pacira BioSciences, Inc.
Filing Date: 2025-08-05
Form: S-8
Chunk 1
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If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. o

### EXPLANATORY NOTE
Pacira BioSciences, Inc. previously filed Registration Statements on Form S-8 with the United States Securities and Exchange Commission (the “SEC”) on June 23, 2011 (File No. 333-175101), June 7, 2012 (File No. 333-181986), June 5, 2014 (File No. 333-196542), June 17, 2016 (File No. 333-212098), August 8, 2019 (File No. 333-233141), August 3, 2021 (File No. 333-258410) and August 2, 2023 (File No. 333-273613) (collectively, the “Prior Registration Statements”), pertaining to, among other things, the registration of shares of common stock, par value $0.001 per share (the “Common Stock”), authorized to be issued pursuant to the Pacira BioSciences, Inc. Amended and Restated 2011 Inducement Plan (as amended and restated to date, the “Plan”). The registrant hereby incorporates by reference the contents of the Prior Registration Statements to the extent not otherwise amended or superseded by the contents of this Registration Statement.

This Registration Statement is being filed pursuant to General Instruction E of Form S-8 to register under the Securities Act of 1933, as amended, the offer and sale of an additional 2,500,000 shares of Common Stock pursuant to the Plan. Pursuant to General Instruction E of Form S-8, the contents of the Prior Registration Statements, to the extent relating to the registration of Common Stock issuable under the Plan, are incorporated herein by reference and made part of this Registration Statement, except as amended, supplemented, or superseded hereby.

# PART II

### INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

## Item 3. Incorporation of Documents by Reference.
The following documents filed by the registrant with the SEC are hereby incorporated by reference in this registration statement:

(1) The registrant’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024, filed with the SEC