Company: SCLXW
Filing Date: 2025-02-26
Form Type: PRER14A
Source: 0001193125-25-036730
Chunk: 2

Company: Scilex Holding Co
Filing Date: 2025-02-26
Form: PRER14A
Chunk 2
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OTE IS IMPORTANT. Whether or not you plan to attend the Special Meeting, we urge you to submit your vote via the Internet or mail as soon as possible to ensure that your shares are represented. For additional instructions on voting by the Internet, please refer to your proxy card. Returning the proxy does not deprive you of your right to attend the Special Meeting and to vote your shares at the Special Meeting. Please note, however, that if your shares are held of record by a broker, bank or other nominee and you wish to vote at the Special Meeting, you must obtain a proxy issued in your name from that record holder. We appreciate your continued support of Scilex. By order of the Board of Directors, Jaisim Shah Chief Executive Officer, President and Director Palo Alto, CA , 2025

TABLE OF CONTENTS

|                                                                |     | PAGE |    |
| PROCEDURAL MATTERS                                             |     |      |  1 |
| PROPOSAL NO. 1 REVERSE STOCK SPLIT PROPOSAL                    |     |      |  9 |
| PROPOSAL NO. 2 ADJOURNMENT PROPOSAL                            |     |      | 23 |
| SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT |     |      | 24 |
| HOUSEHOLDING OF PROXY MATERIALS                                |     |      | 26 |
| OTHER MATTERS                                                  |     |      | 26 |

SCILEX HOLDING COMPANY PROXY STATEMENT FOR SPECIAL MEETING OF STOCKHOLDERS PROCEDURAL MATTERS This proxy statement (this “Proxy Statement”) and the enclosed form of proxy are furnished in connection with the solicitation of proxies by our board of directors (our “Board”) for use at the Special Meeting of Stockholders (the “Special Meeting”) of Scilex Holding Company, a Delaware corporation (the “Company”, “Scilex”, “we”, “us” or “our”), and any postponements, adjournments or continuations thereof. The Special Meeting will be held virtually on Wednesday, March 19, 2025 at 9:00 a.m. Pacific Time via live audio webcast. This Proxy Statement and the accompanying proxy card are first being mailed on or about , 2025 to all stockholders of record entitled to vote at the Special Meeting. The information provided in the “question and answer” format below is for your convenience only and is merely a summary of the information contained in this Proxy