Company: PMVP
Filing Date: 2025-01-28
Form Type: S-8
Source: 0001193125-25-014448
Chunk: 4

Company: PMV Pharmaceuticals, Inc.
Filing Date: 2025-01-28
Form: S-8
Chunk 4
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 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8and has duly caused this Registration Statement on Form S-8to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Princeton, New Jersey, on January 28, 2025.

| PMV PHARMACEUTICALS, INC. |     |                                       |
| By:                       |     | /s/ David H. Mack                     |
|                           |     | David H. Mack, Ph.D.                  |
|                           |     | President and Chief Executive Officer |

POWER OF ATTORNEY KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints David H. Mack, Ph.D. and Michael Carulli as his or her true and lawful attorneys-in-factand agents, with full power of substitution and substitution, for him or her and in their name, place and stead, in any and all capacities, to sign this Registration Statement and any and all amendments thereto (including post-effective amendments), and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-factand agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact,and agents or any of them, or his or her substitute or substitutes, may lawfully do or cause to be done by virtue hereof. Pursuant to the requirements of the Securities Act of 1933, this registration statement on Form S-8has been signed by the following persons in the capacities and on the dates indicated.

| Signature                    
 /s/ David H. Mack            
 David H. Mack, Ph.D.         
 /s/ Michael Carulli          
 Michael Carulli              |     | Title                                                                         
 President, Chief Executive Officer and Director (Principal Executive Officer) 
 Chief Financial Officer (Principal Financial                                  
 and Accounting Officer)                                                       |     | Date             
 January 28, 2025 
 January 28, 2025 |
|:-----------------------------|:----|:------------------------------------------------------------------------------|:----|:-----------------|
| /s/ Richard Heyman