Company: CMA
Filing Date: 2025-08-05
Form Type: 424B5
Source: 0001193125-25-173600
Chunk: 17

Company: COMERICA INC
Filing Date: 2025-08-05
Form: 424B5
Chunk 17
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 Voting Rights | None, except with respect to authorizing or increasing the authorized amount of senior stock (as defined in “Description of the Series B Preferred Stock—Voting Rights”), certain changes in the terms of the Series B Preferred 
 Stock, in the case of certain dividend non-payments, and as required by law. See “Description of the Series B Preferred Stock—Voting Rights.” Holders of depositary shares must act through the                                  
 depositary to exercise any voting rights, as described under “Description of Depositary Shares —Voting the Series B Preferred Stock” below.                                                                                      |

| Ranking | Shares of the Series B Preferred Stock will rank: |

| • |     | senior to our junior stock; |

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| • |     | equally with any series of parity stock we may issue in the future; |

| • |     | junior to any series of stock we may issue in the future that ranks senior to the Series B Preferred Stock in the 
 payment of dividends; and                                                                                         |

| • |     | with respect to distributions of assets upon any liquidation, dissolution or winding up of Comerica, junior to 
 all existing and future indebtedness and other non-equity claims.                                              |

| Preemptive and Conversion Rights | None. |

| Listing | We intend to apply for listing of the depositary shares on the NYSE under the symbol “CMA PrB.” If approved for listing, we expect trading of the depositary shares on the NYSE to commence within 30 days after we issue the depositary 
 shares.                                                                                                                                                                                                                                  |

| Tax Consequences | For discussion of the U.S. federal income tax consequences relating to the depositary shares and the Series B Preferred Stock represented thereby, see “Certain U.S. Federal Income Tax Considerations” in this prospectus supplement. |

| Use of Proceeds | The net proceeds from this offering, after deducting the underwriting discount and estimated offering expenses payable by us, are expected to be approximately $392.2 million. We intend to use the net proceeds from the sale of the depositary 
 shares for general corporate purposes. See “Use of Proceeds.”                                                                                                                                                                                    |

| Risk Factors | Please refer to “Risk Factors” and other information contained or incorporated by reference in this prospectus supplement and the accompanying prospectus for a discussion of factors you should consider carefully before deciding to 
 invest in the depositary shares.                                                                                                                                                                                                       |

| Conflicts of Interest | Comerica Securities, Inc., one