Company: CLM
Filing Date: 2025-04-21
Form Type: 424B3
Source: 0001398344-25-007380
Chunk: 1

Company: Cornerstone Strategic Investment Fund, Inc.
Filing Date: 2025-04-21
Form: 424B3
Chunk 1
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 Offering and (ii) 80% of the market price per Share at
such time. The considerable number of Shares that may be issued as a result of the Offering may cause the premium above NAV at which
the Fund’s Shares are currently trading to decline, especially if Stockholders exercising the Rights attempt to sell sizeable
numbers of shares immediately after such issuance.

STOCKHOLDERS WHO CHOOSE TO EXERCISE THEIR RIGHTS WILL NOT KNOW THE SUBSCRIPTION PRICE PER SHARE AT THE TIME THEY EXERCISE SUCH RIGHTS BECAUSE THE OFFERING WILL EXPIRE ( I.E., CLOSE) PRIOR TO THE AVAILABILITY OF THE FUND’S NAV AND OTHER RELEVANT MARKET INFORMATION ON THE EXPIRATION DATE. ONCE A STOCKHOLDER SUBSCRIBES FOR SHARES AND THE FUND RECEIVES PAYMENT, SUCH STOCKHOLDER WILL NOT BE ABLE TO WITHDRAW HIS, HER OR ITS SUBSCRIPTION OR CHANGE HIS, HER OR ITS DECISION. THE OFFERING WILL EXPIRE AT 5:00 P.M., NEW YORK CITY TIME, ON MAY 16, 2025 (THE “EXPIRATION DATE”), UNLESS EXTENDED, AS DISCUSSED IN THIS PROSPECTUS.

The offering may substantially dilute the voting
power of Stockholders who do not fully exercise their Rights since they will own a smaller proportionate interest in the Fund upon completion
of the offering.

The Fund is a diversified, closed-end management
investment company. The Fund’s investment objective is to seek long-term capital appreciation through investing primarily in the
equity securities of U.S. and non-U.S. companies. There can be no assurance that the Fund’s objective will be achieved.

For more information, please call EQ Fund Solutions
(the “Information Agent”) toll free at (866) 406-2285.

Investing in the Fund involves risks. See “Risk Factors” on page 31 of this prospectus.

|           |     | Estimated    
 Subscription 
 Price(1)     |      |     | Estimated 
 Sales     
 Load      |      |     | Estimated      
 Proceeds to    
 the Fund(2)(3) |             |
|:----------|:----|:-------------|-----:|:----|:----------|:-----|:----|:---------------|------------:|
| Per Share |     | $            | 6.61 |     |           | None |     | $              | 556,907,892 |
| Total     |     |