Company: AEMD
Filing Date: 2025-09-05
Form Type: 424B4
Source: 0001683168-25-006701
Chunk: 4

Company: AETHLON MEDICAL INC
Filing Date: 2025-09-05
Form: 424B4
Chunk 4
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 a condition to closing in this offering, the actual public offering amount,    
 placement agent fees, and proceeds to us, if any, are not presently determinable and may be substantially less than the total maximum 
 offering amounts set forth above. For more information, see “Plan of Distribution.”                                                   |

An investment in our securities involves a high degree of risk. Before deciding whether to invest in our securities, you should consider carefully the risks and uncertainties described in the section captioned “Risk Factors” contained herein and in our Annual Report on Form 10-K for the fiscal year ended March 31, 2025 filed with the Securities and Exchange Commission (the SEC) on June 26, 2025, and other filings we make with the SEC from time to time, which are incorporated by reference herein in their entirety, together with other information in this prospectus and the information incorporated by reference herein.

Neither the SEC nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

Delivery of the common stock,
pre-funded warrants and accompanying warrants offered in the Company Offering is expected to be made on or about September 5, 2025 subject
to satisfaction of certain customary closing conditions.

<div align='center'>Maxim Group LLC

The date of this Prospectus is September 4, 2025</div>

<div align='center'>TABLE OF CONTENTS</div>

|                                                   | Page |
| About this Prospectus                             |    1 |
| Prospectus Summary                                |    2 |
| Risk Factors                                      |   21 |
| Special Note Regarding Forward-Looking Statements |   25 |
| Use of Proceeds                                   |   27 |
| Selling Securityholders                           |   28 |
| Dilution                                          |   30 |
| Description of Capital Stock                      |   31 |
| Description of Securities                         |   33 |
| Certain Material U.S. Federal Tax Consequences    |   36 |
| Plan of Distribution                              |   40 |
| Legal Matters                                     |   49 |
| Experts                                           |   49 |
| Market and Industry Data                          |   49 |
| Where You Can Find More Information               |   49 |
| Incorporation of Certain Information by Reference |   50 |

| i |

<div align='center'>ABOUT THIS PROSPECTUS</div>

You should read this prospectus, including the information
incorporated by