Company: TAK
Filing Date: 2025-10-30
Form Type: 6-K
Source: 0001395064-25-000152
Chunk: 6

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-10-30
Form: 6-K
Chunk 6
---
 of the Medicare Part D redesign and 340B program expansion in the U.S., this was offset by stable demand in other regions and for other products. Revenue outside of our six key business areas was JPY 103.1 billion (JPY -23.7 billion and -18.7% AER, -17.5% CER).

<div align='center'>2</div>

Takeda Pharmaceutical Company Limited (4502)

Earnings Report ( Kessan Tanshin ) for the Six-month

Period Ended September 30, 2025 (Consolidated)

#### Revenue by Geographic Region
The following shows revenue by geographic region:

|                                |     |           |         |     |            |         |     |          |        |     |          |       |   |     |     |      | Billion JPY or percentage |
|                                |     | FY2024 H1 |         |     | FY2025 H1  |         |     | AER      |        |     |          |       |   |     | CER |      |                           |
| Revenue:                       |     |           |         |     | JPY Change |         |     | % Change |        |     | % Change |       |   |     |     |      |                           |
| Japan                          |     |           |   216.4 |     |            |   219.1 |     |          |    2.7 |     |          |   1.2 | % |     |     |  1.3 | %                         |
| United States                  |     |           | 1,247.6 |     |            | 1,091.9 |     |          | -155.7 |     |          | -12.5 | % |     |     | -7.9 | %                         |
| Europe and Canada              |     |           |   533.0 |     |            |   535.2 |     |          |    2.2 |     |          |   0.4 | % |     |     |  0.8 | %                         |
| Latin America                  |     |           |   132.5 |     |            |   118.5 |     |          |  -14.0 |     |          | -10.6 | % |     |     | -5.4 | %                         |
| China                          |     |