Company: RCUS
Filing Date: 2025-10-31
Form Type: 424B5
Source: 0001193125-25-260836
Chunk: 58

Company: Arcus Biosciences, Inc.
Filing Date: 2025-10-31
Form: 424B5
Chunk 58
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 our option or the 
 holders’ option) conversion or exchange features, the applicable conversion or exchange period and the manner of settlement for any conversion or exchange;                                                                                               |

| • |     | if other than the full principal amount thereof, the portion of the principal amount of debt securities of the 
 series which shall be payable upon declaration of acceleration of the maturity thereof;                        |

| • |     | additions to or changes in the covenants applicable to the particular debt securities being issued, including, 
 among others, the consolidation, merger or sale covenant;                                                      |

| • |     | additions to or changes in the events of default with respect to the securities and any change in the right of                                     
 the trustee or the holders to declare the principal, premium, if any, and interest, if any, with respect to such securities to be due and payable; |

| • |     | additions to or changes in or deletions of the provisions relating to covenant defeasance and legal defeasance; |

| • |     | additions to or changes in the provisions relating to satisfaction and discharge of the indenture; |

| • |     | additions to or changes in the provisions relating to the modification of the indenture both with and without the 
 consent of holders of debt securities issued under the indenture;                                                 |

| • |     | the currency of payment of debt securities if other than U.S. dollars and the manner of determining the 
 equivalent amount in U.S. dollars;                                                                      |

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| • |     | whether interest will be payable in cash or additional debt securities at our or the holders’ option and 
 the terms and conditions upon which the election may be made;                                            |

| • |     | the terms and conditions, if any, upon which we will pay amounts in addition to the stated interest, premium, if                            
 any and principal amounts of the debt securities of the series to any holder that is not a “United States person” for federal tax purposes; |

| • |     | any restrictions on transfer, sale or assignment of the debt securities of the series; and |

| • |     | any other specific terms, preferences, rights or limitations of, or restrictions on, the debt securities, any                                              
 other additions or changes in the provisions of the indenture, and any terms that may be required by us or advisable under applicable laws or regulations. |

Conversion or Exchange Rights We will set forth in the applicable prospectus supplement the terms on which a series of debt securities may be convertible into