Company: INMB
Filing Date: 2025-06-16
Form Type: S-8
Source: 0001213900-25-054428
Chunk: 1

Company: Inmune Bio, Inc.
Filing Date: 2025-06-16
Form: S-8
Chunk 1
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 to Section 7(a)(2)(B) of the Securities Act. ☐

<div align='center'>EXPLANATORY NOTE</div>

This Registration Statement also includes a prospectus
(the “reoffer prospectus”) prepared in accordance with General Instruction C of Form S-8 and in accordance with the requirements
of Part I of Form S-3. This reoffer prospectus for shares granted under the INmune Bio Inc. 2017 Stock Incentive Plan (the “2017
Plan”) and INmune Bio Inc. 2019 Stock Incentive Plan (the “2019 Plan”) may be used for the reoffer and resale of shares
of common stock on a continuous or delayed basis that may be deemed to be “restricted securities” and/or “control securities”
within the meaning of the Securities Act of 1933, as amended (the “Securities Act”), and the rules and regulations promulgated
thereunder, that are issuable to certain of our executive officers, employees, consultants and directors identified in the reoffer
prospectus. The number of shares of common stock included in the reoffer prospectus represents shares of common stock issuable
to the selling stockholders pursuant to equity awards, including stock options and restricted stock grants, granted to the selling stockholders
and does not necessarily represent a present intention to sell any or all such shares of common stock.

<div align='center'>PART I

INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>

This Registration Statement relates to two separate
prospectuses.

: Items 1 and 2,
from this page, and the documents incorporated by reference pursuant to Part II, Item 3 of this prospectus, constitute a prospectus that
meets the requirements of Section 10(a) of the Securities Act.

: The material that follows
Item 2, up to but not including Part II of this Registration Statement, of which the reoffer prospectus is a part, constitutes a “reoffer
prospectus,” prepared in accordance with the requirements of Part I of Form S-3 under the Securities Act. Pursuant to Instruction
C of Form S-8, the reoffer prospectus may be used for reoffers or resales of shares of common stock which are deemed to be “control
securities” or “restricted securities” under the Securities Act that have been acquired by the selling stockholders
named in the reoffer prospectus.

Item