Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 153

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 153
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 without reference to the mergers (except as expressly set forth below in the section entitled “Certain Estimated Synergies and Adjustments Attributable to the
Mergers”). In addition, since the prospective financial information covers multiple years, such information by its nature becomes subject to greater uncertainty with each successive year. These and the other estimates and assumptions
underlying the prospective financial information involve judgments with respect to, among other things, economic, competitive, regulatory and financial market conditions and future business decisions that may not be realized and that are inherently
subject to significant business, economic, competitive and regulatory uncertainties and contingencies, including, among other things, the inherent uncertainty of the business, economic and regulatory conditions affecting the industries in which
Fifth Third and Comerica operate and the risks and uncertainties described under the sections entitled “Risk Factors” beginning on page 50 of this joint proxy statement/prospectus and “Cautionary Statement Regarding Forward-Looking Statements” beginning on page 48 of this joint proxy statement/prospectus and in the reports that Fifth Third and Comerica file with the SEC from time to time, all of which are difficult to predict and many of which are
outside the control of Fifth Third and Comerica and will be beyond the control of Fifth Third following the completion of the mergers. There can be no assurance that the underlying assumptions or projected results will be realized, and actual
results could differ materially from those reflected in the prospective financial information, whether or not the mergers are completed. Further, the underlying assumptions do not include all potential actions that the senior management of Fifth
Third or Comerica could or might have taken during the applicable time periods. The inclusion in this joint proxy statement/prospectus of the prospective financial information below should not be regarded as an indication that Fifth Third, Comerica
or their respective boards of directors or advisors considered, or now consider, this prospective financial information to be material

103

information to any Fifth Third shareholders or Comerica stockholders, as the case may be, particularly in light of the inherent risks and uncertainties associated with such prospective financial
information.

The prospective financial information should not be construed as financial guidance, and it should not be relied on as such. This
information was prepared solely for internal use and is subjective in many respects and thus is susceptible to multiple interpretations and periodic revisions based on actual experience and business developments. The prospective financial
information is not fact and should not be relied upon as necessarily indicative of actual future results.