Company: NYXH
Filing Date: 2025-03-20
Form Type: S-8
Source: 0001104659-25-026165
Chunk: 0

Company: Nyxoah SA
Filing Date: 2025-03-20
Form: S-8
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission
on March 20, 2025</div>

Registration No. 333-

<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM S-8

REGISTRATION STATEMENT UNDER

THE SECURITIES ACT OF 1933

NYXOAH SA

(Exact name of registrant as specified in its charter)</div>

| Belgium                                       
 (State or other jurisdiction of incorporation 
 or organization)                              |     | Not Applicable                       
 (I.R.S. Employer Identification No.) |

<div align='center'>Rue Edouard Belin 12

1435 Mont-Saint-Guibert, Belgium(Address of principal executive offices)

2025 Warrants Plan

(Full title of the plans)

Corporation Service Company

1090 Vermont Avenue N.W.

Washington D.C. 20005

United States

Telephone: +1 800 927 9800

(Name, address and telephone number, including
area code, of agent for service)

Copies to:</div>

| John T. Rudy, Esq.          
 Jason S. McCaffrey, Esq.    
 Mintz, Levin, Cohn, Ferris, 
 Glovksy & Popeo, P.C.       
 One Financial Center        
 Boston, MA 02111            
 (617) 542 6000              | Philippe Remels          
 NautaDutilh              
 BV/SRL                   
 Chaussée de La Hulpe 120 
 1000 Brussels, Belgium   
 +32 2 566 80 00          |

Indicate by check mark whether the registrant
is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company.
See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,”
and “emerging growth company” in Rule 12b-2 of the Exchange Act.

| Large accelerated 
 filer ¨           | Accelerated         
 filer x             |
| Non-accelerated   
 filer ¨           | Smaller             
 reporting company ¨ |
|                   | Emerging            
 growth company x    |

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards