Company: RCUS
Filing Date: 2025-02-18
Form Type: 424B5
Source: 0001193125-25-028669
Chunk: 37

Company: Arcus Biosciences, Inc.
Filing Date: 2025-02-18
Form: 424B5
Chunk 37
---
us supplement. The price to the public of such
securities and the net proceeds we expect to receive from such sale will also be set forth in a prospectus supplement.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

The date of this prospectus is February 28, 2023

TABLE OF CONTENTS

| ABOUT THIS PROSPECTUS                             |     |  i |
| PROSPECTUS SUMMARY                                |     |  1 |
| RISK FACTORS                                      |     |  6 |
| SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS |     |  7 |
| USE OF PROCEEDS                                   |     |  9 |
| DESCRIPTION OF CAPITAL STOCK                      |     | 10 |
| DESCRIPTION OF DEBT SECURITIES                    |     | 14 |
| DESCRIPTION OF WARRANTS                           |     | 21 |
| LEGAL OWNERSHIP OF SECURITIES                     |     | 23 |
| PLAN OF DISTRIBUTION                              |     | 26 |
| LEGAL MATTERS                                     |     | 28 |
| EXPERTS                                           |     | 28 |
| WHERE YOU CAN FIND ADDITIONAL INFORMATION         |     | 28 |
| INCORPORATION OF CERTAIN INFORMATION BY REFERENCE |     | 28 |

ABOUT THIS PROSPECTUS

This prospectus is part of an automatic registration statement on Form S-3 that we filed with the Securities and Exchange Commission, or
SEC, using a “shelf” registration process as a “well-known seasoned issuer” as defined in Rule 405 under the Securities Act of 1933, as amended, or the Securities Act. Under this shelf registration statement, we may, from time to
time, offer and sell, either individually or in combination, in one or more offerings, any combination of the securities described in this prospectus. There is no limit on the aggregate amount of the securities that we may offer pursuant to the
registration statement of which this prospectus is a part.

This prospectus provides you with a general description of the securities we
may offer. Each time we offer securities under this prospectus, we will provide a prospectus supplement that will contain more specific information about the terms of that offering. We may also authorize one or more free writing prospectuses to be
provided to you that may contain material information relating to these offerings.