Company: APM
Filing Date: 2025-01-03
Form Type: 424B5
Source: 0001213900-25-000606
Chunk: 55

Company: Aptorum Group Ltd
Filing Date: 2025-01-03
Form: 424B5
Chunk 55
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 the debenture trustee reasonable indemnity. The holders of a majority in principal
amount of the outstanding debt securities of any series will have the right to direct the time, method and place of conducting any proceeding
for any remedy available to the debenture trustee, or exercising any trust or power conferred on the debenture trustee, with respect to
the debt securities of that series, provided that:

| ● | the direction so given by the holder is not in conflict with 
 any law or the applicable indenture; and                     |

| ● | subject to its duties under the Trust Indenture Act of 1939,                                                                             
 the debenture trustee need not take any action that might involve it in personal liability or might be unduly prejudicial to the holders 
 not involved in the proceeding.                                                                                                          |

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A holder of the debt securities
of any series will only have the right to institute a proceeding under the indentures or to appoint a receiver or trustee, or to seek
other remedies if:

| ● | the holder has given written notice to the debenture trustee  
 of a continuing event of default with respect to that series; |

| ● | the holders of at least 25% in aggregate principal amount                                                                               
 of the outstanding debt securities of that series have made written request, and such holders have offered reasonable indemnity, to the 
 debenture trustee to institute the proceeding as trustee; and                                                                           |

| ● | the debenture trustee does not institute the proceeding and                                                                           
 does not receive from the holders of a majority in aggregate principal amount of the outstanding debt securities of that series other 
 conflicting directions within 90 days after the notice, request and offer.                                                            |

These limitations do not apply
to a suit instituted by a holder of debt securities if we default in the payment of the principal, premium, if any, or interest on, the
debt securities.

We will periodically file
statements with the debenture trustee regarding our compliance with specified covenants in the indentures.

Modification of Indenture; Waiver

We and the debenture trustee
may change an indenture without the consent of any holders with respect to specific matters, including:

| ● | to fix any ambiguity, defect or inconsistency in the indenture; |

| ● | to comply with the provisions described above under “Consolidation, 
 Merger or Sale”;                                                    |

| ● | to comply with any requirements of the SEC in connection with