Company: TVRD
Filing Date: 2025-02-14
Form Type: 424B3
Source: 0001104659-25-014310
Chunk: 415

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-02-14
Form: 424B3
Chunk 415
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#### Vote Required; Recommendation of the Cara Board
**The affirmative vote of a majority of the votes cast by holders of shares present at the meeting (by virtual attendance) or by represented by proxy and voting on the matter at the Cara special meeting is required to approve Proposal No. 4. Abstentions and broker non-votes will have no effect on the outcome of this proposal. It is anticipated that Proposal No. 4 will be a non-discretionary proposal considered non-routine under the rules of the NYSE, which generally controls the ability of brokers to vote or not vote shares held in street name on certain matters, and thus may result in broker non-votes.

THE CARA BOARD RECOMMENDS THAT CARA’S COMMON STOCKHOLDERS VOTE “FOR” PROPOSAL NO. 4 TO APPROVE THE AMENDMENT TO THE CARA AMENDED AND RESTATED CERTIFICATE OF INCORPORATION EFFECTING THE REVERSE STOCK SPLIT. THE APPROVAL OF EACH OF PROPOSAL NOS. 1, 4 AND 5 IS REQUIRED TO CONSUMMATE THE MERGER.**

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TABLE OF CONTENTS

<div align='center'>**PROPOSAL NO. 5 (THE AUTHORIZED SHARE PROPOSAL): INCREASE IN AUTHORIZED SHARES**</div>

The Cara Board has determined that it is advisable to increase the authorized number of shares of Cara common stock from 16,666,667 shares to 150,000,000 shares, and has voted to recommend that the stockholders adopt an amendment to Cara’s amended and restated certificate of incorporation effecting the proposed increase. The full text of the proposed amendment to Cara’s amended and restated certificate of incorporation is attached to this proxy statement as Annex G.

As of January 15, 2025, and assuming a 1-for-2 Reverse Stock Split to the implemented immediately prior to the closing of the Merger and upon the approval of the Reverse Stock Split Proposal, 2,285,614 shares of Cara common stock were issued and outstanding (excluding treasury shares) and approximately an additional 259,637 shares of Cara common stock were reserved for issuance upon the settlement of outstanding RSUs and exercise of outstanding options granted under our various stock-based plans. In addition, a total of approximately 247,137 and 12,500 shares of Cara common stock are available for future issuance under the 2014 Plan and 2019 Plan, respectively.