Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 10

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 10
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Comerica Incorporated Comerica Bank Tower 1717 Main Street, MC 6404 Dallas, Texas 75201 NOTICE OF SPECIAL MEETING OF COMERICA STOCKHOLDERS To Comerica Stockholders: On October 5, 2025, Fifth Third Bancorp (“Fifth Third”), Fifth Third Financial Corporation (“Fifth Third Intermediate”), Comerica Incorporated (“Comerica”) and Comerica Holdings Incorporated (“Comerica Holdings”) entered into an Agreement and Plan of Merger (as amended, modified or supplemented from time to time in accordance with its terms, the “merger agreement”), a copy of which is attached as Annex Ato the accompanying joint proxy statement/prospectus. A summary of the merger agreement is included in the section of the accompanying joint proxy statement/prospectus entitled “ The Merger Agreement” beginning on page 119, and each of the Merger Agreement and such summary are incorporated by reference into this notice to the same extent as if fully set forth herein. NOTICE IS HEREBY GIVEN that a special meeting (the “Comerica special meeting”) of holders of Comerica common stock will be held virtually via the Internet on January 6, 2026 at 9:00 a.m., Eastern Standard Time, at www.meetnow.global/MPJJCLF. We are pleased to notify you of and invite you to the Comerica special meeting. At the Comerica special meeting you will be asked to vote on the following matters:

| • |     | A proposal to adopt the merger agreement (the “Comerica merger proposal”); |

| • |     | A proposal to approve, on an advisory (non-binding) basis, the                                                                                                                       
 merger-related compensation payments that will or may be paid to Comerica’s named executive officers in connection with the first merger (the “Comerica compensation proposal”); and |

| • |     | A proposal to approve the adjournment or postponement of the special meeting, if necessary or appropriate, to                                                                                                                                             
 solicit additional proxies if, immediately prior to such adjournment, there are not sufficient votes to approve the Comerica merger proposal or to ensure that any supplement or amendment to the accompanying joint proxy statement/prospectus is timely 
 provided (the “Comerica adjournment proposal”).                                                                                                                                                                                                           |

The Comerica special meeting is expected to be held in a virtual-only format conducted via live webcast. In order to attend the Comerica special meeting via