Company: WSBC
Filing Date: 2025-09-11
Form Type: 424B5
Source: 0001193125-25-201360
Chunk: 32

Company: WESBANCO INC
Filing Date: 2025-09-11
Form: 424B5
Chunk 32
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 rights and rights upon liquidation, dissolution or winding-upof Wesbanco. The issuance of such senior series of capital stock must be approved by the requisite holders of at least two-thirdsof the outstanding Series B Preferred Stock and all other stock on a parity with the Series B Preferred Stock, including our Series A Preferred Stock, voting together as a single class. See “Description of the Series B Preferred Stock — Voting Rights.” Dividends Dividends on shares of the Series B Preferred Stock are discretionary, not mandatory, and will not be cumulative. Holders of the Series B Preferred Stock will be entitled to receive, if, when, and as declared by our board of directors or a duly authorized committee of our board of directors, out of legally available assets, non-cumulativecash dividends quarterly in arrears on January 1, April 1, July 1 and October 1 of each year, beginning on January 1, 2026 (each such date being referred to herein as a “dividend payment date”) based on the liquidation preference of $1,000 per share (equivalent to $25 per depositary share) at a rate equal to:

| • |     | from the date of original issue to, but excluding, the First Reset Date, a fixed rate per annum of 7.375%; and |

S-24

| • |     | from, and including, the First Reset Date, during each reset period, a rate per annum equal to the five-year 
 treasury rate as of the most recent dividend determination rate (as described below) plus 3.795%.            |

In the event that we issue additional shares of Series B Preferred Stock after the original issue date, dividends on such shares may accrue from the original issue date or any other date we specify at the time such additional shares are issued. References to the “accrual” of dividends in this prospectus supplement refer only to the determination of the amount of such dividend and do not imply that any right to a dividend arises prior to the date on which a dividend is declared. We will not pay interest or any sum of money instead of interest on any dividend payment that may be in arrears on the Series B Preferred Stock. Dividends will be payable to holders of record of Series B Preferred Stock as they appear on our books on the applicable record date (each such date being referred to herein as a “dividend record date”), which shall be the 15th calendar day before the dividend payment