Company: NMZ
Filing Date: 2025-07-07
Form Type: N-CSRS
Source: 0001193125-25-156000
Chunk: 2

Company: NUVEEN MUNICIPAL HIGH INCOME OPPORTUNITY FUND
Filing Date: 2025-07-07
Form: N-CSRS
Chunk 2
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 offering under these Shelf Offerings are as shown in the accompanying table.

|                            |     | NVG |           |     | NMZ |           |     | NMCO |             |     |         NDMO |
| Maximum aggregate offering |     |     | Unlimited |     |     | Unlimited |     |      | $70,100,000 |     | $363,900,000 |

During the current reporting period, NMZ sold common shares through its Shelf Offering at a weighted average premium to its NAV per common share in the accompanying table.

|                                                       |     |       NMZ |
| Common shares sold through shelf offering             |     | 2,397,700 |
| Weighted average premium to NAV per common share sold |     |     1.25% |

Refer to Notes to Financial Statements, for further details on Shelf Offerings and each Fund’s transactions.

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COMMON SHARE REPURCHASES The Funds’ Board of Trustees reauthorized an open-market share repurchase program, allowing each Fund to repurchase and retire an aggregate of up to approximately 10% of its outstanding common shares. During the current reporting period, the Funds did not repurchase any of their outstanding common shares. As of April 30, 2025, (and since the inception of the Funds’ repurchase programs), each Fund has cumulatively repurchased and retired its outstanding common shares as shown in the accompanying table.

|                                         |     | NVG |            |     | NZF |            |     | NMZ |            |     | NMCO |           |     | NDMO |           |
| Common shares repurchased and retired   |     |     |    202,500 |     |     |     67,500 |     |     |          0 |     |      |         0 |     |      |         0 |
| Common shares authorized for repurchase |     |     | 21,350,000 |     |     | 19,370,000 |     |     | 11,320,000 |     |      | 5,480,000 |     |      | 5,955,000 |

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About the Funds’ Benchmarks S&P Municipal Bond High Yield Index: An index designed to measure the performance of tax-exempthigh yield municipal bonds. Index returns assume reinvestment of distributions, but do not reflect any applicable sales charges or management fees. S&P Municipal Bond Index: An index designed