Company: NCNA
Filing Date: 2025-04-24
Form Type: F-1
Source: 0001193125-25-092131
Chunk: 11

Company: NuCana plc
Filing Date: 2025-04-24
Form: F-1
Chunk 11
---
 and the information contained on or accessible through our website are not part of this prospectus. Our agent for service of process in the United States is Corporation Service Company, 251 Little Falls Drive,
Wilmington, DE 19808. The SEC maintains an internet site that contains reports, proxy and information statements, and other information regarding issuers that file electronically with the SEC (http://www.sec.gov).

Recent Developments

On April 23, 2025,
we held a general meeting of our ordinary shareholders, or the GM, at Lochside House, 3 Lochside Way, Edinburgh, EH12 9DT, United Kingdom. All of the resolutions set out in our notice of the GM dated March 18, 2025 and furnished on Form 6-K with the
SEC on March 18, 2025 were duly proposed and passed, including the following resolutions:

1. As an ordinary resolution, that, in
accordance with section 618 of the Companies Act 2006 and subject to the passing of Resolution 3 below, each of the 151,923,897 ordinary shares of £0.04 each in the issued share capital of the Company be and is sub-divided into and
redesignated as (i) 1 ordinary share of £0.0004, having the same rights and being subject to the same restrictions (except as to nominal value) as the existing ordinary shares in the capital of the Company, as set out in the Company’s
articles of association from time to time and (ii) 99 deferred shares of £0.0004 each, having the rights and being subject to the restrictions set out in the Company’s articles of association (to be adopted pursuant to Resolution 3
below and thereafter as amended and

2

adopted from time to time), such that, following the passing of this resolution, the Company’s issued share capital shall be comprised of 151,923,897 ordinary shares and 15,040,465,803
deferred shares, in each case, of £0.0004 each.

2. As an ordinary resolution, that, subject to the passing of Resolution 1, the
board of directors be generally and unconditionally authorized pursuant to Section 551 of the Companies Act 2006 to exercise all the powers of the Company to allot shares in the Company or grant rights to subscribe for or to convert any
security into shares in the Company up to an aggregate nominal amount of £20,000,000