Company: NCNA
Filing Date: 2025-05-02
Form Type: F-1/A
Source: 0001193125-25-110310
Chunk: 16

Company: NuCana plc
Filing Date: 2025-05-02
Form: F-1/A
Chunk 16
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 accompanying Warrants will equal the price per ADS and accompanying Warrants being sold to the public in this offering, minus the                    
 United States dollar equivalent of £0.01, based on the exchange rate on the date of pricing, and the exercise price of each Pre-Funded Warrant will be equal to the United States dollar equivalent of 
 £0.01, based on the exchange rate on the date of exercise.                                                                                                                                             |

| Each Pre-Funded Warrant will be immediately exercisable and may be exercised at any time until exercised in full. There is no expiration date for the Pre-Funded Warrants. There is no established trading market for the Pre-Funded Warrants, and we do not expect a market to develop. We do not intend to apply for a listing for 
 the Pre-Funded Warrants on any securities exchange or other nationally recognized trading system. Without an active trading market, the liquidity of the Pre-Funded                                                                                                                                                                  
 Warrants will be limited.                                                                                                                                                                                                                                                                                                            |

| To better understand the terms of the Pre-Funded Warrants, you should carefully read the “Description of Securities We Are Offering” section of this prospectus. |

| Series A Warrants offered by us | Each ADS and each Pre-Funded Warrant to purchase one ADS is being sold together with a Series A Warrant to purchase one ADS. Each Series A Warrant will have an exercise price equal to 125% of the combined 
 public offering price, will be exercisable at any time beginning on the Initial Exercise Date and will expire on the five-year anniversary of the Initial Exercise Date.                                     |

| This prospectus also relates to the offering of the ADSs issuable upon exercise of the Series A Warrants. Because we will issue a Series A Warrant for each ADS and for each 
 Pre-Funded Warrant sold in this offering, the number of Series A Warrants sold in this offering will not change as a result of a change in the mix of the ADSs and           
 Pre-Funded Warrants sold.                                                                                                                                                    |

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| To better understand the terms of the Series A Warrants, including the cashless exercise option, you should carefully read the “Description of Securities We Are Offering” section of this prospectus. |

| Series B Warrants offered by us | Each ADS and each Pre-Funded Warrant to purchase one ADS is being sold together with a Series B Warrant to purchase one ADS. Each Series B Warrant will have an exercise price equal to 250% of the combined