Company: IMRX
Filing Date: 2025-08-13
Form Type: S-3
Source: 0001104659-25-077655
Chunk: 54

Company: Immuneering Corp
Filing Date: 2025-08-13
Form: S-3
Chunk 54
---
 to be an “underwriter” within the meaning of the Securities Act, and the compensation of Piper Sandler will be deemed to be underwriting commissions or discounts. We have agreed to indemnify Piper Sandler against certain civil liabilities, including liabilities under the Securities Act. We have also agreed to contribute to payments Piper Sandler may be required to make in respect of such liabilities.

The offering of our shares of Class A common stock pursuant to the Equity Distribution Agreement will terminate upon the earlier of (i) the sale of all shares of Class A common stock subject to the Equity Distribution Agreement and (ii) the termination of the Equity Distribution Agreement as permitted therein. We and Piper Sandler may each terminate the sales agreement at any time upon specified prior notice.

This summary of the material provisions of the Equity Distribution Agreement does not purport to be a complete statement of its terms and conditions. A copy of the Equity Distribution Agreement is filed as an exhibit to the registration statement to which this prospectus supplement relates and is incorporated by reference herein.

<div align='center'>S-13</div>

TABLE OF CONTENTS

Piper Sandler and its affiliates have provided, and may in the future provide, various investment banking, financial advisory and other financial services for us and our affiliates, for which services they have received, and may in the future receive, customary fees. In the course of its business, Piper Sandler may actively trade our securities for its own account or for the accounts of customers, and, accordingly, Piper Sandler may at any time hold long or short positions in such securities.

A prospectus supplement and the accompanying prospectus in electronic format may be made available on a website maintained by Piper Sandler, and Piper Sandler may distribute the prospectus supplement and the accompanying prospectus electronically.

<div align='center'>S-14</div>

TABLE OF CONTENTS

### LEGAL MATTERS
Latham & Watkins LLP will pass upon certain legal matters relating to the issuance and sale of the shares of Class A common stock offered hereby on behalf of Immuneering Corporation. Certain legal matters will be passed upon for Piper Sandler & Co. by Sidley Austin LLP.

### EXPERTS
The consolidated financial statements of Immuneering Corporation as of December 31, 2024 and 2023 and for each of the years in the two-year period ended December 31, 2024 incorporated in this Prospectus Supplement by reference from the Immuneering Corporation Annual Report on Form 10-K for the year ended December 31