Company: JUNS
Filing Date: 2025-10-28
Form Type: PRER14A
Source: 0001493152-25-019793
Chunk: 1

Company: JUPITER NEUROSCIENCES, INC.
Filing Date: 2025-10-28
Form: PRER14A
Chunk 1
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 PN, Ltd. (“ Yorkville”), including upon conversion of convertible promissory notes issued to Yorkville in connection with the SEPA.

The changes to the Original Proxy Statement as reflected in this Amended Proxy Statement include updates and other conforming changes based on the additional proposal and change of Annual Meeting date. You should read this proxy statement in its entirety and in place of the Original Proxy Statement.

<div align='center'>JUPITER NEUROSCIENCES, INC.</div>

November[●], 2025

Dear Stockholders:

We invite you to attend the 2025 virtual Annual Meeting of Stockholders (the “ Annual Meeting”) of Jupiter Neurosciences, Inc. (“ Jupiter,” the “ Company,” “ us,” “ our,” or “ we”). The Annual Meeting will be held in a virtual meeting format on December 19, 2025 at 10:00 a.m. Eastern Time. You may attend, vote and submit questions during the Annual Meeting via the Internet at https://meetings.lumiconnect.com/200-142-773-960. We have designed the format of the Annual Meeting to ensure that you are afforded the same rights and opportunities to participate as you would at an in-person meeting, using online tools to ensure your access and participation.

The Notice of the Annual Meeting and Proxy Statement accompanying this letter provide information concerning matters to be considered and acted upon at the meeting. Immediately following the meeting, a report on our operations will be presented, including a question-and-answer and discussion period. Our 2024 results are presented in detail in our Annual Report, which is available for viewing at www.astproxyportal.com/ast/29363.

Your vote is very important.We encourage you to read the Proxy Statement and vote your shares as soon as possible. Whether or not you plan to attend, you can be sure your shares are represented at the Annual Meeting by promptly submitting your vote by the Internet, by telephone or, if you request a paper copy of the proxy materials and receive a proxy card, by mail.

On behalf of the Board of Directors, thank you for your continued confidence and investment in Jupiter.

| Christer          
 Rosén             |
| Chief             
 Executive Officer |

<div align='center'>JUPITER NEUROSCIENCES, INC.

1001 North US HWY 1, Suite 504

Jupiter, FL 33477

Telephone: (561) 406-6154

NOTICE OF 2025 ANNUAL MEETING OF STOCKHOLDERS