Company: SMNR
Filing Date: 2025-12-03
Form Type: S-8
Source: 0001193125-25-306962
Chunk: 1

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-12-03
Form: S-8
Chunk 1
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000 shares of the Company’s common stock, par value $0.0001 per share (“Common Stock”), issuable upon exercise of
outstanding stock options previously granted under the Semnur Pharmaceuticals, Inc. 2024 Stock Option Plan (the “Plan”), of which options were assumed by the Company in connection with the business combination effected on
September 22, 2025 (the “Business Combination”) pursuant to that certain Agreement and Plan of Merger, dated as of August 30, 2024 (as amended, restated or supplemented from time to time, including by Amendment No. 1 to
Agreement and Plan of Merger, dated April 16, 2025, and by Amendment No. 2 to Agreement and Plan of Merger, dated July 22, 2025) (the “Merger Agreement”), by and among the Company (formerly known as Denali Capital
Acquisition Corp.), Denali Merger Sub Inc., our then-wholly owned subsidiary, and the pre-Business Combination Semnur Pharmaceuticals, Inc. (now named Semnur, Inc.).

This Registration Statement also includes a reoffer prospectus (the “Reoffer Prospectus”) prepared in accordance with General
Instruction C of Form S-8 and in accordance with the requirements of Part I of Form S-3. This Reoffer Prospectus may be used for the reoffer and resale of
shares of Common Stock on a continuous or delayed basis that may be deemed to be “control securities” within the meaning of the Securities Act of 1933, as amended (the “Securities Act”), and the rules and regulations
promulgated thereunder, that are issuable to certain of our executive officers and directors identified in the Reoffer Prospectus. The number of shares of Common Stock included in the Reoffer Prospectus represents shares of Common Stock issuable to
the selling stockholders pursuant to stock options granted to the selling stockholders and does not necessarily represent a present intention to sell any or all such shares of Common Stock. The number of shares of Common Stock to be offered or
resold by means of the Reoffer Prospectus by the selling stockholders, and any other person with whom any of them is acting in concert for the purpose of selling Common Stock, may not exceed, during any three-month period, the amount specified in
Rule 144(e) under the Securities Act.

PART I

INFORMATION REQUIRED IN THE SECTION 10(A) PROSPECTUS

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