Company: RPTX
Filing Date: 2025-12-03
Form Type: PREM14A
Source: 0001193125-25-306948
Chunk: 11

Company: Repare Therapeutics Inc.
Filing Date: 2025-12-03
Form: PREM14A
Chunk 11
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angement Resolution not later than 5:00 p.m. (Montreal time) on January 14, 2026, being the Business Day which is two Business Days immediately preceding the Special
Meeting (or, if the Special Meeting is postponed or adjourned, by 5:00 p.m. (Montreal time) on the Business Day which is two Business Days immediately preceding the date of the postponed or adjourned Special Meeting) and otherwise comply strictly
with the dissent procedures of Chapter XIV – Division I of the QBCA, as modified by the Plan of Arrangement, the Interim Order and any other order of the Superior Court of Québec, as described in the Circular and Proxy Statement. This
right is described in detail in the Circular and Proxy Statement under the heading “Dissent Rights.” The text of Chapter XIV – Division I of the QBCA, which will be relevant in any dissent proceeding, is set forth in Annex C
to the Circular and Proxy Statement.

Beneficial owners of Common Shares registered in the name of a broker, investment dealer or other
intermediary who wish to dissent should be aware that only Registered Shareholders as of the Record Date are entitled to dissent. Beneficial Shareholders who wish to exercise dissent rights must cause each Registered Shareholder holding their Common
Shares to deliver the notice of dissent or make arrangements for such Common Shares to be re-registered in their names.

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Failure to strictly comply with the dissent procedures described in the Circular and Proxy Statement may result in the loss of any right of dissent. It is strongly suggested that any Shareholder wishing to dissent seek independent legal advice. All Shareholders are cordially invited to attend the Special Meeting. The Arrangement is described in the accompanying Circular and Proxy Statement, which we urge you to read carefully. A copy of the Agreement is included as Annex A to the Circular and Proxy Statement and is available on the Company’s profile on EDGAR at www.sec.gov and on SEDAR+ at www.sedarplus.ca. Please review the Circular and Proxy Statement before you cast your vote.

| By Order of the Board of Directors, |     |                                                                |
|                                     |     | Steve Forte                                                    |
|                                     |     | President, Chief Executive Officer and Chief Financial Officer |

The date of the Circular and Proxy Statement is , 2025 and, together with the enclosed form of proxy card, it is first being mailed to Shareholders on or about , 2025. 4

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