Company: SMNR
Filing Date: 2025-08-13
Form Type: 424B3
Source: 0001193125-25-179226
Chunk: 599

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-08-13
Form: 424B3
Chunk 599
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 meeting of stockholders to be held in 2025;                                                           |

| • |     | The Class II directors will be Dorman Followwill and Yue Alexander Wu, Ph.D. and their term will expire at 
 the annual meeting of stockholders to be held in 2026; and                                                 |

| • |     | The Class III directors will be Henry Ji, Ph.D. and Jaisim Shah and their term will expire at the annual 
 meeting of stockholders to be held in 2027.                                                              |

At each annual meeting of stockholders to be held after the initial classification, the successors to directors whose terms will then expire will be elected to serve from the time of election and qualification until the third annual 378

meeting following their election. The authorized number of directors that shall constitute the New Semnur Board will be determined exclusively by the New Semnur
Board;provided that, at any time the Scilex Group beneficially owns, in the aggregate, at least 50% in voting power of the then-outstanding shares of New Semnur’s capital stock entitled to vote generally in the election of
directors, the stockholders may also fix the number of directors by resolutions adopted by the stockholders. Any increase or decrease in the number of directors will be apportioned among the three classes so that, as nearly equal as practicable,
each class will consist of one-third of the directors. No decrease in the number of directors constituting the New Semnur Board will shorten the term of any incumbent director. New Semnur’s directors may
be removed with or without cause by the affirmative vote of the holders of a majority of voting power of the then-outstanding shares of New Semnur’s capital stock entitled to vote generally in the election of such directors;provided, however, that, from and after the Scilex Trigger Event any such director or all such directors may be removed only for cause and only by the affirmative vote of the holders of at least 66 2/3% in voting power of all the then-outstanding shares
of New Semnur’s capital stock entitled to vote thereon, voting together as a single class.

Subject to applicable law and the Proposed Charter and
subject to the rights of the holders of any series of preferred stock of New Semnur, any vacancy on the New Semnur Board may be filled by the New Semnur Board or the stockholders of New Semnur;provided, however, that from and after