Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 174

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 174
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 DiamiR’s product commercialization as a result of, these laws and regulations.

DiamiR’s operations are affected by various state, federal, and
international healthcare, environmental, anti-corruption, fraud and abuse (including anti-kickback and false claims laws), privacy, and
employment laws as well as international political sanctions. Violations of these laws and sanctions can result in criminal or civil penalties,
including substantial fines and, in some cases, exclusion from participation in federal health care programs such as Medicare and Medicaid.
In some cases, the violation of such laws could potentially lead to individual liability and imprisonment.

DiamiR is also subject to regulation by the FDA pursuant to the Federal
Food, Drug, and Cosmetic Act (“FDCA”), by comparable agencies in foreign countries and by other regulatory agencies and governing
bodies. Following the introduction of a product, these and other government agencies will periodically review DiamiR’s manufacturing
processes, product performance and compliance with applicable requirements.

DiamiR is also subject to various U.S. healthcare related laws
regulating sales, contracting, marketing, and other business arrangements and the use and disclosure of individually identifiable health
information. These include but are not limited to:

| ● | The federal Anti-Kickback Statute, a criminal law, which prohibits                                                                          
 persons and entities from knowingly and willfully offering, paying, providing, soliciting, or receiving any remuneration, directly or       
 indirectly, in cash or in kind, in exchange for or to induce or reward the referral of an individual, or the purchasing, leasing, ordering, 
 recommending, furnishing or arranging for a good or service, for which payment may be made under a federal health care program, such        
 as Medicare or Medicaid. A person or entity does not need to have actual knowledge of the statute or specific intent to violate it in       
 order to have committed a violation. Violations of the federal Anti-Kickback Statute can result in significant civil monetary penalties     
 and criminal fines, as well as imprisonment and exclusion from participation in federal healthcare programs.                                |

| ● | The federal False Claims Act, which imposes significant civil                                                                                
 penalties, treble damages and potential exclusion from participation in federal healthcare programs against any person or entity that,       
 among other things, knowingly presents, or causes to be presented, to the federal government claims for payment that are false or fraudulent 
 or for making a false record or statement material to an obligation to pay the federal government or for knowingly and improperly avoiding,