Company: SION
Filing Date: 2025-01-17
Form Type: S-1
Source: 0001193125-25-008474
Chunk: 359

Company: Sionna Therapeutics, Inc.
Filing Date: 2025-01-17
Form: S-1
Chunk 359
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 of incorporation, which will become effective immediately prior to the completion of this offering, and the amended and restated bylaws, which will become effective upon the effectiveness of the registration statement of which this prospectus forms a part, that limit or eliminate the personal liability of our directors to the fullest extent permitted by the DGCL, as it now exists or may in the future be amended. Consequently, a director will not be personally liable to us or our stockholders for monetary damages or breach of fiduciary duty as a director, except for liability for:

| • |     | any breach of the director’s duty of loyalty to us or our stockholders; |

| • |     | any act or omission not in good faith or that involves intentional misconduct or a knowing violation of law; |

II-1

| • |     | any unlawful payments related to dividends or unlawful stock purchases, redemptions or other distributions; or |

| • |     | any transaction from which the director derived an improper personal benefit. |

These limitations of liability do not alter director liability under the federal securities laws and do not affect the availability of equitable remedies such as an injunction or rescission. In addition, our amended and restated bylaws will provide that:

| • |     | we will indemnify our directors, officers and, in the discretion of our board of directors, certain employees to the 
 fullest extent permitted by the DGCL, as it now exists or may in the future be amended; and                          |

| • |     | we will advance reasonable expenses, including attorneys’ fees, to our directors and, in the discretion of our board                                                       
 of directors, to our officers and certain employees, in connection with legal proceedings relating to their service for or on behalf of us, subject to limited exceptions. |

We have entered into indemnification agreements with each of our directors and intend to enter into such agreements with our executive officers. These agreements provide that we will indemnify each of our directors, our executive officers and, at times, their affiliates to the fullest extent permitted by Delaware law. We will advance expenses, including attorneys’ fees (but excluding judgments, fines and settlement amounts), to each indemnified director, executive officer or affiliate in connection with any proceeding in which indemnification is available and we will indemnify our directors and officers for any action or proceeding arising out of that person’s services as a director or officer brought on behalf of us or in furtherance of our rights. Additionally, certain of our directors or officers may have certain rights to