Company: CMA
Filing Date: 2025-08-05
Form Type: 424B5
Source: 0001193125-25-173600
Chunk: 60

Company: COMERICA INC
Filing Date: 2025-08-05
Form: 424B5
Chunk 60
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 the 
 disposition and certain other conditions exist; or                                                        |

| • |     | under the U.S. Foreign Investment In Real Property Tax Act, we are or have been a U.S. real property holding                                                                                                                   
 corporation for U.S. federal income tax purposes and certain other conditions are met. We have not been, are not and do not anticipate becoming a U.S. real property holding corporation for U.S. federal income tax purposes. |

Gain described in the first bullet point above generally will be subject to U.S. federal income tax on a net income basis at the regular applicable U.S. federal income tax rates in the same manner as if you were a U.S. person. A non-U.S.holder that is a corporation may, under certain circumstances, be subject to an additional branch profits tax at a 30% rate or such lower rate as specified by an applicable income tax treaty of its “effectively connected earnings and profits” for the taxable year, subject to certain adjustments. Gain described in the second bullet point above will be subject to a flat 30% tax on the gain derived from the disposition (or such lower rate as may be specified by an applicable income tax treaty), which may be offset by U.S.-source capital losses, if any, for the taxable year, provided that the non-U.S.holder has timely filed U.S. federal income tax returns with respect to such losses. As discussed above under “U.S. Holders—Redemptions,” an amount paid to a holder of depositary shares in connection with a redemption of the depositary shares may, under certain circumstances, be treated as a dividend. In that case, the payment would be subject to the rules for dividends described above under “Non-U.S.Holders—Distributions.” S-41

Foreign Account Tax Compliance Act

The Foreign Account Tax Compliance Act (“FATCA”) may impose a 30% withholding tax on U.S. source dividend payments to certain foreign
financial institutions, investment funds and other non-U.S. persons that fail to comply with information reporting requirements. You could be affected by this withholding with respect to your depository shares
if you are subject to the information reporting requirements and fail to comply with them or if you hold depository shares through another person (e.g., a foreign bank or broker) that is subject to withholding and such person fails to comply with
these requirements (even if you would not otherwise have been subject to withholding).

You should consult your own tax advisors regarding
the relevant U