Company: SHPH
Filing Date: 2025-11-07
Form Type: 8-K
Source: 0001493152-25-021256
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Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-11-07
Form: 8-K
Item: Item 1.01
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Item
1.01. Entry into a Material Definitive Agreement.

Securities
Purchase Agreement

On
November 3, 2025, Shuttle Pharmaceuticals Holdings, Inc. (the “ Company”) entered into a securities purchase agreement (the
“ Purchase Agreement”) with the purchaser named therein (the “ Purchaser”), pursuant to which the Company agreed
to issue and sell to the Purchaser in a private placement transaction (the “ Offering”) a pre-funded warrant (the “ Pre-Funded
Warrant”) to purchase up to 625,156 shares of common stock of the Company, par value $0.00001 per share (the “ Common Stock”)
for aggregate gross proceeds of approximately $2.5 million, before deducting placement agent fees to WestPark Capital, Inc. (the “ Placement
Agent”) and offering expenses payable by the Company. The Offering closed on November 4, 2025.

The
Pre-Funded Warrant has an exercise price of $0.001 per share of Common Stock, subject to proportional adjustments in the event of stock
splits or combinations or similar events, is immediately exercisable on the date of issuance and remains exercisable until exercised
in full. The holder of the Pre-Funded Warrant may not exercise the Pre-Funded Warrant if the holder, together with its affiliates,
would beneficially own more than 4.99% of the number of shares of Common Stock outstanding immediately after giving effect to such exercise.
The holder of the Pre-Funded Warrant may increase or decrease such percentage not in excess of 9.99%, and in the case of an increase,
by providing at least 61 days’ prior notice to the Company.

Pursuant
to the Purchase Agreement, the Company agreed to file a registration statement (the “ Registration Statement”) with the U. S.
Securities and Exchange Commission (the “ SEC”) on or before the date that is fifteen (15) days after the date of the Purchase
Agreement for purposes of registering the resale of the shares of Common Stock issuable upon the exercise of the Pre-Funded Warrant and
to have such Registration Statement declared effective on or before the date that is forty-five (45) days after the date of the Purchase
Agreement (or seventy-five (75) days if the SEC determines to review the Registration Statement).

The
issuance and sale of the Pre-Funded Warrant was not registered under the Securities Act of 1933, as amended (the