Company: SHPH
Filing Date: 2025-01-24
Form Type: 424B3
Source: 0001493152-25-003508
Chunk: 61

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-01-24
Form: 424B3
Chunk 61
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 - |   |     | For the Nine Months Ended 
 September 30,             
 2024                      |          - |   |     | 2023 |          - |   |
|:---------------------------------------------------------------|:----|:--------------------|-----------:|:--|:----|:--------------|-----------:|:--|:----|:--------------------------|-----------:|:--|:----|:-----|-----------:|:--|
| Operating expenses                                             |     | $                   |  5,892,382 |   |     | $             |  2,343,826 |   |     | $                         |  5,919,042 |   |     | $    |  4,609,558 |   |
| Loss from operations                                           |     | $                   | (5,892,382 | ) |     | $             | (2,343,826 | ) |     | $                         | (5,919,042 | ) |     | $    | (4,609,558 | ) |
| Other income (expense)                                         |     | $                   |   (700,341 | ) |     | $             | (2,652,243 | ) |     | $                         | (1,627,286 | ) |     | $    |   (342,665 | ) |
| Net loss                                                       |     | $                   | (6,592,723 | ) |     | $             | (4,996,069 | ) |     | $                         | (7,546,328 | ) |     | $    | (4,952,223 | ) |
| Weighted average common shares outstanding – basic and diluted |     |                     |  1,886,275 |   |     |               |  1,337,742 |   |     |                           |  2,189,366 |   |     |      |  1,820,006 |   |
| Net loss per share – basic and diluted                         |     | $                   |      (3.53 | ) |     | $             |      (5.04 | ) |     | $                         |      (3.45 | ) |     | $    |      (2.72 | ) |

| 43 |

<div align='center'>PRIVATE PLACEMENT OF THE SENIOR SECURED CONVERTIBLE NOTES AND WARRANTS</div>

In October 2024, we entered into securities purchase agreements