Company: SXTPW
Filing Date: 2025-07-07
Form Type: S-1
Source: 0001213900-25-061842
Chunk: 85

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-07-07
Form: S-1
Chunk 85
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orporated by reference to Exhibit 4.2 of the Current Report on Form 8-K filed on February 6, 2025)                             |
| 10.14*      |     | Form of Securities Purchase Agreement                                                                                                                                                                                                    |
| 21.1**      |     | List of Subsidiaries of the Registrant                                                                                                                                                                                                   |
| 23.1*       |     | Consent of RBSM LLP                                                                                                                                                                                                                      |
| 23.2*       |     | Consent of Sichenzia Ross Ference Carmel LLP (included in Exhibit 5.1)                                                                                                                                                                   |
| 24.1*       |     | Power of Attorney (included in the signature page to this registration statement)                                                                                                                                                        |
| 107*        |     | Filing Fee Table.                                                                                                                                                                                                                        |

| * | Filed herewith. |

| ** | Incorporated by reference to the Registrant’s Registration Statement No. 333-269483, filed on January 31, 2023. |

| + | Management contract or compensatory plan. |

| ++ | Parts of certain information have been redacted. |

<div align='center'>II-7

SIGNATURES</div>

Pursuant to the requirements of the Securities
Act of 1933, as amended, the registrant has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto
duly authorized in the City of Washington, District of Columbia, on July 7, 2025.

| 60 DEGREES PHARMACEUTICALS, INC. |                                       |
| By:                              | /s/                                   
 Geoffrey Dow                          |
|                                  | Geoffrey Dow                          |
|                                  | President and Chief Executive Officer 
 (Principal Executive Officer)         |

<div align='center'>POWER OF ATTORNEY</div>

KNOW ALL BY THESE PRESENTS, that each person whose
signature appears below constitutes and appoints Geoffrey Dow as his or her true and lawful attorneys-in-fact and agents, each with the
full power of substitution, for him or her and in his or her name, place or stead, in any and all capacities, to sign any and all amendments
to this registration statement (including post-effective amendments), and to sign any registration statement for the same offering covered
by this registration statement that is to be effective upon filing pursuant to Rule 462(b) promulgated under the Securities
Act, and all post-effective amendments thereto, and