Company: IMNN
Filing Date: 2025-07-22
Form Type: 424B5
Source: 0001641172-25-020519
Chunk: 1

Company: Imunon, Inc.
Filing Date: 2025-07-22
Form: 424B5
Chunk 1
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us supplement and does not include the shares of Common Stock previously sold pursuant to the Sales Agreement.

As of the date of this prospectus supplement, the
aggregate market value of our outstanding Common Stock held by non-affiliates was approximately $79,075,969, based on 31,828,425
shares of Common Stock outstanding as of the date of this prospectus supplement, of which 31,504,370 shares are held by non-affiliates,
and a price of $2.51 per share, which was the last reported sale price of our Common Stock on The Nasdaq Stock Market LLC (“Nasdaq”)
on June 2, 2025. As a result, our public float has increased above $75.0 million, and we are no longer subject to the limitations
contained in General Instruction I.B.6 of Form S-3 as of the date of this prospectus supplement. If we become subject to the offering
limits in General Instruction I.B.6 of Form S-3 in the future, we will file another prospectus supplement.

Our Common Stock is listed on Nasdaq under the symbol
“IMNN.” On July 18, 2025, the last reported sale price for our Common Stock on Nasdaq was $0.552 per share.

The validity of the shares being offered hereby will be passed upon by Thompson Hine LLP.

Investing in our securities involves a high degree of risk. Before making an investment decision, please read “Risk Factors” beginning on page S-3 of the ATM Prospectus Supplement and the other documents and information contained or incorporated by reference in this prospectus supplement and the ATM Prospectus Supplement.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus supplement is truthful or complete. Any representation to the contrary is a criminal offense.

<div align='center'>H.C. Wainwright & Co.

The date of this prospectus supplement is July 22, 2025</div>