Company: SXTPW
Filing Date: 2025-06-06
Form Type: DRS
Source: 0001213900-25-052232
Chunk: 37

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-06-06
Form: DRS
Chunk 37
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 to invest in our securities.                                                                                                                                                                                                                                                                                          |
| Transfer Agent and registrar |     | Equity Stock Transfer, LLC                                                                                                                                                                                                                                                                                                                                                                                              |
| Reasonable best efforts      |     | The placement agent has agreed to use its reasonable best efforts to arrange for the sale of the securities offered by this prospectus. The placement agent is not purchasing or selling any of the securities we are offering and the placement agent is not required to arrange the purchase or sale of any specific number of securities or dollar amount. See “Plan of Distribution” on page 35 of this prospectus. |
| Dividend Policy              |     | We have never declared or paid any cash dividends on our shares of common stock. We do not anticipate paying any cash dividends in the foreseeable future.                                                                                                                                                                                                                                                              |

| (1) | The number of shares of common stock to be outstanding after this offering                
 is based on 1,472,891 shares of Common Stock outstanding as of June 6, 2025 and excludes: |

| ● | 57,068                                                                   
 shares of common stock reserved for future issuance under the 2022 Plan; |

| ● | 2,127,070 shares of common stock issuable upon exercise of outstanding warrants at a weighted 
 average exercise price of $15.85 per share;                                                   |

| ● | 137,637                                                                                                                            
 shares of common stock issuable upon exercise of outstanding options at a weighted average exercise price of $13.92 per share; and |

| ● | shares                                                                                     
 of common stock issuable upon the conversion of 76,480 shares of Series A Preferred Stock. |

| (2) | Unless                                                                
 otherwise indicated, this prospectus supplement reflects and assumes: |

| ● | no                                                                                                                    
 exercise of the options and warrants described above or the exercise of the Warrants or the Placement Agent Warrants. |

<div align='center'>17

RISK FACTORS</div>

Investing in our common stock involves a high degree of risk. You should carefully consider the risks described below, and those discussed under the section title “Risk Factors” contained in our Annual Report on Form 10-K for the year ended December 31, 2024, together with other information in this prospectus, the information and documents incorporated by reference herein, and in any free writing prospectus that we have authorized for use in connection with this offering. Our business is subject to many risks and uncertainties, which may affect our future financial performance. If any of the events or circumstances described below