Company: TVRD
Filing Date: 2025-02-14
Form Type: S-4/A
Source: 0001104659-25-013053
Chunk: 716

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-02-14
Form: S-4/A
Chunk 716
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 ​ | ​ | ​ | ​    | ​ | ​ | ​                       | ​ | 33,705 | ​ | ​ | ​ | ​                                               | ​ | -16,384 | ​ | ​ | ​ | ​    | ​ | ​ | ​                 | ​ | 17,321 | ​ | ​ |

416

TABLE OF CONTENTS

| ​                                                                             | ​ | ​ | Historical                |   |          |   | ​ | ​ | ​                                                                      | ​ |       ​ | ​ | ​ | ​ | ​    | ​ | ​ | As Adjusted           |   |          |   | ​ | ​ | Historical                  |   |         |   | ​ | ​ | ​                                                          | ​ |      ​ | ​ | ​ | ​ | ​    | ​ | ​ | As Adjusted             |   |         |   | ​ | ​ | ​                                               | ​ |        ​ | ​ | ​ | ​ | ​    | ​ | ​ | ​                 | ​ |       ​ | ​ | ​ |
| ​                                                                             | ​ | ​ | 6(A)CaraTherapeutics,Inc. |   |          |   | ​ | ​ | TransactionAccountingAdjustments −AssetDispositionand OtherAdjustments |   |         |   | ​ | ​ | ​    | ​ | ​ | CaraTherapeutics,Inc. |   |          |   | ​ | ​ | 6(B)TvardiTherapeutics,Inc. |   |         |   | ​ | ​ | TransactionAccountingAdjustments −ConvertibleNoteFinancing |   |        |   | ​ | ​ | ​    | ​ | ​ | TvardiTherapeutics,Inc. |   |         |   | ​ | ​ | TransactionAccountingAdjustments −ReverseMerger |   |          |   | ​ | ​ | ​    | ​ | ​ | Pro FormaCombined |   |         |   | ​ |
| Liability related to sales of future royalties and milestones, net            | ​ | ​ | ​                         | ​ |   40,583 | ​ | ​ | ​ | ​                                                                      | ​ | -40,583 | ​ | ​ | ​ | 6(c) | ​ | ​ | ​                     | ​ |        — | ​ | ​ | ​ | ​                           | ​ |       — | ​ | ​ | ​ | ​                                                          | ​ |      ​ | ​ | ​ | ​ | ​    | ​ | ​ |