Company: CMA
Filing Date: 2025-08-05
Form Type: 424B5
Source: 0001193125-25-173600
Chunk: 45

Company: COMERICA INC
Filing Date: 2025-08-05
Form: 424B5
Chunk 45
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 The Series B Preferred Stock is not convertible into or exchangeable for property or shares of any other series or class of our capital stock. S-29

Registrar

Computershare Trust Company, N.A. will be the transfer agent and registrar, Computershare Inc. will be the dividend disbursing agent, and
Computershare Trust Company, N.A. and Computershare Inc. will jointly be the redemption agent for the Series B Preferred Stock.

Calculation Agent

Unless we have validly called all shares of the Series B Preferred Stock for redemption on the First Reset Date, we will appoint a
calculation agent for the Series B Preferred Stock prior to the rate determination date related to the First Reset Date. We may appoint ourselves or an affiliate of ours as calculation agent.

S-30

DESCRIPTION OF DEPOSITARY SHARES

In this prospectus supplement, references to “holders” of depositary shares mean those who own depositary shares registered in their
own names, on the books that we or the depositary maintain for this purpose, and not indirect holders who own beneficial interests in depositary shares registered in street name or issued in book-entry form through DTC. Please review the special
considerations that apply to indirect holders described in the “Book-Entry Issuance” section of this prospectus supplement.

This prospectus supplement summarizes specific terms and provisions of the depositary shares representing the Series B Preferred Stock and
supersedes any conflicting description in the prospectus. As described above under “Description of the Series B Preferred Stock” and elsewhere in this prospectus supplement, we are issuing fractional interests in shares of the Series B
Preferred Stock in the form of depositary shares. Each depositary share will represent a 1/40th ownership interest in a share of the Series B Preferred Stock, and will be evidenced by a depositary receipt. The shares of Series B Preferred Stock
represented by depositary shares will be deposited under a deposit agreement among us, Computershare Inc., as joint depositary and Computershare Trust Company, N.A., as registrar and joint depositary, and the holders from time to time of the
depositary receipts evidencing the depositary shares. Subject to the terms of the deposit agreement, each holder of a depositary share will be entitled, through the depositary, in proportion to the applicable fraction of a share of Series B
Preferred Stock represented by such depositary share, to all the rights and preferences of the Series B Preferred Stock represented thereby (including