Company: GHRS
Filing Date: 2025-07-29
Form Type: 20-F/A
Source: 0001140361-25-027850
Chunk: 0

Company: GH Research PLC
Filing Date: 2025-07-29
Form: 20-F/A
Chunk 0
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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F/A Amendment No. 1 (Mark One)

| ☐ | REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 |

OR

| ☒ | ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |

For the fiscal year ended December 31, 2024 OR

| ☐ | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |

OR

| ☐ | SHELL COMPANY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |

Commission file number: 001-40530 GH Research PLC (Exact name of Registrant as specified in its charter) Ireland (Jurisdiction of incorporation or organization) Joshua Dawson House Dawson Street Dublin 2 D02 RY95 Ireland (Address of principal executive offices) Velichka Valcheva, MD, MSc Chief Executive Officer Joshua Dawson House Dawson Street Dublin 2 D02 RY95 Ireland + 353 1 437 8334 (Name, Telephone, E-mail and/or Facsimile number and Address of Company Contact Person) Copies to: Deanna L. Kirkpatrick Yasin Keshvargar Davis Polk & Wardwell LLP 450 Lexington Avenue New York, NY 10017 (212) 450-4000 Securities registered or to be registered pursuant to Section 12(b) of the Act:

| Title of each class                             | Trading Symbol | Name of each exchange on which registered |
| Ordinary shares, nominal value $0.025 per share | GHRS           | TheNasdaqStock Market LLC                 |

Securities registered or to be registered pursuant to Section 12(g) of the Act: None Securities for which there is a reporting obligation pursuant to Section 15(d) of the Act: None Indicate the number of outstanding shares of each of the issuer’s classes of capital or common stock as of the close of the period covered by the annual report.

| Title of Class  | Number of Shares Outstanding |
| Ordinary shares |                   52,028,145 |

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule