Company: CMND
Filing Date: 2025-12-03
Form Type: 424B5
Source: 0001213900-25-117534
Chunk: 1

Company: Clearmind Medicine Inc.
Filing Date: 2025-12-03
Form: 424B5
Chunk 1
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| Where                             
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| Incorporation                     
 of Certain Documents by Reference |     |   29 |
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| Expenses                          |     |   30 |

<div align='center'>S-i

ABOUT THIS PROSPECTUS SUPPLEMENT</div>

A registration statement
on Form F-3 (File No. 333-275991) utilizing a shelf registration process relating to the securities described in this prospectus supplement
was declared effective on December 26, 2023. Under that shelf registration statement, of which this prospectus supplement is a part,
we may, from time to time, sell up to an aggregate of $50 million of Common Shares, warrants and units. As of December 2, 2025, we have
sold approximately $8.05 million of our securities under that shelf registration statement. We sometimes refer to the Common Shares
as the “securities” throughout this prospectus.

This document contains two parts. The first part is this prospectus supplement, which describes the terms of this offering of the Common Shares, and also adds, updates and changes information contained in the accompanying prospectus and the documents incorporated herein and therein by reference. The second part is the accompanying prospectus, which gives more general information about us, some of which may not apply to this offering. You should read both this prospectus supplement and the accompanying prospectus, including the information incorporated by reference herein and therein. To the extent the information contained in this prospectus supplement differs or varies from the information contained in the accompanying prospectus or any document filed prior to the date of this prospectus supplement and incorporated herein or therein by reference, the information in this prospectus supplement will control; provided, that if any statement in one of these documents is inconsistent with a statement in another document having a later date, the statement in the document having the later date modifies or supersedes the earlier statement. In addition, this prospectus supplement and the accompanying prospectus do not contain all of the information provided in the registration statement that we filed with the SEC that contains the accompanying prospectus (including the exhibits to the registration statement). For further information about us, you should refer to that registration statement, which you can obtain