Company: SCLXW
Filing Date: 2025-09-29
Form Type: 424B3
Source: 0001193125-25-221018
Chunk: 118

Company: Scilex Holding Co
Filing Date: 2025-09-29
Form: 424B3
Chunk 118
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 dividends, stock combinations and
other similar transactions of the Common Stock that occur after the date of this Agreement.

5.17 . IN ANY ACTION, SUIT, OR PROCEEDING IN ANY JURISDICTION BROUGHT BY ANY PARTY AGAINST ANY OTHER PARTY, THE PARTIES EACH KNOWINGLY AND INTENTIONALLY, TO THE GREATEST EXTENT PERMITTED BY APPLICABLE LAW, HEREBY ABSOLUTELY, UNCONDITIONALLY,
IRREVOCABLY AND EXPRESSLY WAIVES FOREVER TRIAL BY JURY.

(Signature Pages Follow)

IN WITNESS WHEREOF, the parties hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first indicated above.

| COMPANY                                  |     |                                              |
| DATAVAULT AI INC.                        |     |                                              |
| By:                                      |     | /s/ Nathaniel Bradley                        |
|                                          |     | Name: Nathaniel Bradley Title: Chief         
 Executive Officer                            |
| Email Address: Address for Notice        
 to Company:                              |     |                                              |
| PURCHASER                                |     |                                              |
| SCILEX HOLDING COMPANY                   |     |                                              |
| By:                                      |     | /s/ Henry Ji                                 |
|                                          |     | Name: Henry Ji, Ph.D. Title: Chief Executive 
 Officer                                      |
| Email Address: hji@scilexholding.com     |     |                                              |
| Address for Notice to Purchaser:         
 960 San Antonio Road Palo Alto, CA 94303 |     |                                              |

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Exhibit 99.1

FOR IMMEDIATE RELEASE

September 25, 2025

Scilex Holding Company Announces $150 Million Strategic Bitcoin Investment in Datavault AI

PALO ALTO, CALIFORNIA – September 26, 2025 (GLOBE NEWSWIRE) - Scilex Holding Company (“Scilex” or the “Company”) (Nasdaq:
SCLX), an innovative revenue-generating company focused on acquiring, developing and commercializing non-opioid pain management products for the treatment of acute and chronic pain and neurodegenerative and
cardiometabolic disease, today announced that it has entered into an agreement to make a $150 million Bitcoin (BTC) investment in Datavault AI Inc. (Nasdaq: DVLT, “Datavault”), which