Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 10

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 10
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 percentage of our total
outstanding shares of our Common Stock after any such issuance.

Corporate Information

Our principal executive offices
are located at 626 Bancroft Way, Suite A, Berkeley, CA 94710, and our telephone number is (925) 997-6925. Our website address
is www.profusa.com. Information on our website is not part of this prospectus. We have included our website address as an inactive
textual reference only. The information on or accessible through our website is not part of this prospectus supplement and the accompanying
prospectus.

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THE OFFERING

| Shares of common stock offered by the Selling Stockholders                                                 |     | Up to 42,594,048 shares of common stock comprising (i) 42,211,548 shares                                                                                                                                                                                        
 of Common Stock by Ascent of which we may, at our election, issue and sell to Ascent pursuant to the Purchase Agreement from time to time                                                                                                                       
 after the date of this prospectus, subject to the satisfaction of specified conditions and (ii) 382,500 shares issued to certain parties                                                                                                                        
 in satisfaction of transaction costs incurred in connection with the Business Combination we completed on July 11, 2025.                                                                                                                                        |
| Shares of common stock outstanding (as of October 8, 2025)                                                 |     | 41,759,307 shares of Common Stock                                                                                                                                                                                                                               |
| Shares of common stock outstanding after giving effect to the issuance of the shares registered hereunder: |     | 83,453,355 shares of Common Stock                                                                                                                                                                                                                               |
| Use of proceeds                                                                                            |     | We will not receive any proceeds from the                                                                                                                                                                                                                       
 sale of the Resale Securities by the Selling Stockholders. However, we may receive up to $100,000,000 in aggregate gross proceeds from                                                                                                                          
 sales of the Purchase Shares to Ascent that we may, in our discretion, elect to make, from time to time after the date of this prospectus,                                                                                                                      
 pursuant to the Purchase Agreement.                                                                                                                                                                                                                             
 The net proceeds from sales, if any, under the Purchase Agreement,                                                                                                                                                                                              
 will depend on the frequency and prices at which we sell the Purchase Shares to Ascent after the date of this prospectus. To the extent                                                                                                                         
 we sell Purchase Shares to Ascent, we intend to use any proceeds therefrom for the purchase of Bitcoin (which can be used for debt repayment)