Company: RPTX
Filing Date: 2025-04-29
Form Type: DEF 14A
Source: 0001193125-25-103764
Chunk: 1

Company: Repare Therapeutics Inc.
Filing Date: 2025-04-29
Form: DEF 14A
Chunk 1
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 in-person meeting. We believe that holding the Annual Meeting as a completely virtual meeting will enable us to avoid the costs and complexities associated with meetings held in a hybrid format while preserving a format that encourages U.S. and Canadian shareholder inclusion and participation. In addition, with a view to ensure that all shareholders will have equal opportunities to participate and vote at the Annual Meeting from wherever they may physically be located on June 17, 2025, we have updated certain of our disclosures to specify how shareholders can make or comment on motions or raise points of order through our virtual Annual Meeting web platform. We encourage you to attend online and participate. We recommend that you log in a few minutes before 10:00 a.m., Eastern Time on June 17, 2025 to ensure you are logged in when the Annual Meeting starts.

The Annual Meeting will be held for the following purposes:

1.To elect the four nominees of our board of directors, David Bonita, M.D., Thomas Civik, Carol A. Schafer and Steven Stein, M.D., to our board of directors as Class II directors, each to hold office until our Annual Meeting of Shareholders in 2028 and until such director’s successor has been duly elected, or if sooner, until the director’s death, resignation or removal.

2.To approve, on an advisory basis, the compensation of our named executive officers, as disclosed in the accompanying proxy statement.

3.To appoint Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2025, and to authorize our board of directors to fix Ernst & Young LLP’s remuneration.

4.To conduct any other business properly brought before the Annual Meeting.

These items of business are more fully described in the proxy statement accompanying this Notice.

The Annual Meeting will be held virtually through a live webcast. You will be able to attend the Annual Meeting virtually, submit questions and vote during the live webcast by visiting www.proxydocs.com/RPTXand registering prior to the deadline of 5:00 p.m., Eastern Time on June 16, 2025 and entering the Control Number included in your Notice of Internet Availability,voting instruction form, or in the instructions that you received

via email. Upon completing your registration, you will receive further instructions via email, including your unique links that will allow you access to the Annual Meeting and will permit you to submit questions. If you are a shareholder of the Company, you may submit a question in advance of the Annual Meeting at www.proxy