Company: BDRX
Filing Date: 2025-05-12
Form Type: 424B3
Source: 0001214659-25-007342
Chunk: 65

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-05-12
Form: 424B3
Chunk 65
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and Restated Deposit Agreement dated December 18, 2023, among the Company, JPMorgan Chase Bank, N.A., as depositary, and holders and beneficial
owners of American Depositary Receipts, or the Deposit Agreement. The depositary registers and delivers the Depositary Shares. Each Depositary
Share represents ownership of 10,000 Ordinary Shares that we will deposit with the custodian, as agent of the depositary, under the Deposit
Agreement.

The depositary’s office is located at 383 Madison Avenue, Floor
11, New York, NY 10179.

The Depositary Share-to-share
ratio is subject to amendment as provided in the form of American Depositary Receipt, or ADR (which may give rise to fees contemplated
by the form of ADR). In the future, each Depositary Share will also represent any securities, cash or other property deposited with the
depositary but which they have not distributed directly to you.

A beneficial owner is any person or entity having a beneficial ownership
interest in Depositary Shares. A beneficial owner need not be the holder of the ADR evidencing such Depositary Share. If a beneficial
owner is not an ADR holder, it must rely on the holder of the ADR(s) evidencing such Depositary Shares in order to assert any rights or
receive any benefits under the Deposit Agreement. A beneficial owner shall only be able to exercise any right or receive any benefit under
the Deposit Agreement solely through the holder of the ADR(s) evidencing the Depositary Shares owned by such beneficial owner. The arrangements
between a beneficial owner and the holder of the corresponding ADRs may affect the beneficial owner’s ability to exercise any rights
it may have.

An ADR holder shall be deemed to have all requisite authority to act
on behalf of any and all beneficial owners of the Depositary Shares evidenced by the ADRs registered in such ADR holder’s name for
all purposes under the Deposit Agreement and ADRs. The depositary’s only notification obligations under the Deposit Agreement and
the ADRs is to registered ADR holders. Notice to an ADR holder shall be deemed, for all purposes of the Deposit Agreement and the ADRs,
to constitute notice to any and all beneficial owners of the Depositary Shares evidenced by such ADR holder’s ADRs.

Unless certificated ADRs are
specifically requested, all Depositary Shares will be issued on the books of our depositary in