Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 265

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 265
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 |
| General and administrative         |     |                     |   624,388 |   |     |      |   614,074 |   |     |        |   10,314 |   |
| Total operating costs and expenses |     |                     | 1,274,979 |   |     |      | 1,770,934 |   |     |        | (495,955 | ) |
| Loss from operations               |     |                     |  (643,250 | ) |     |      |  (451,403 | ) |     |        | (191,847 | ) |
| Other expense                      |     |                     |           |   |     |      |           |   |     |        |          |   |
| Interest expense                   |     |                     |    82,046 |   |     |      |    48,599 |   |     |        |   33,447 |   |
| Total other expense                |     |                     |    82,046 |   |     |      |    48,599 |   |     |        |   33,447 |   |
| Net loss before income taxes       |     |                     |  (725,296 | ) |     |      |  (500,002 | ) |     |        | (225,294 | ) |
| Income taxes                       |     |                     |    17,939 |   |     |      |   114,403 |   |     |        |  (96,464 | ) |
| Net loss                           |     | $                   |  (743,235 | ) |     | $    |  (614,405 | ) |     | $      | (128,830 | ) |

<div align='center'>147</div>

Revenue

Grant revenue was $531,729
for the year ended May 31, 2025 compared to $1,319,531 for the year ended May 31, 2024. The decrease was due to lower reimbursable
direct labor, consulting and other development expenses for DiamiR’s CogniMIR product candidate corresponding to
the depletion of available grant funding in January 2025. As of May 31, 2025, DiamiR has no remaining funds under its grants
and grant revenues will decrease significantly or cease in future periods.

Other revenue in the year ended
May 31, 2025 consists of non