Company: PFSA
Filing Date: 2025-05-15
Form Type: 424B3
Source: 0001213900-25-044417
Chunk: 292

Company: Profusa, Inc.
Filing Date: 2025-05-15
Form: 424B3
Chunk 292
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-------:|:--|:----|:------|-------:|:--|:----|:------|-------:|:--|
| Lumee Oxygen            |     | $     | — |     | $     | 10.91 |     | $     | 42.63 |   |     | $     |  96.96 |   |     | $     | 176.73 |   |     | $     | 282.25 |   |     | $     | 359.87 |   |     | $     | 413.85 |   |     | $     | 444.89 |   |     | $     | 467.13 |   |
| Annual growth rate (%)  |     |       |   |     |       |       |     |       |   291 | % |     |       |    127 | % |     |       |     82 | % |     |       |     60 | % |     |       |     28 | % |     |       |     15 | % |     |       |      8 | % |     |       |      5 | % |
| Lumee Glucose           |     | $     | — |     | $     |  0.96 |     | $     | 57.07 |   |     | $     | 174.22 |   |     | $     | 308.46 |   |     | $     | 502.75 |   |     | $     | 703.86 |   |     | $     | 844.63 |   |     | $     | 929.09 |   |     | $     | 975.54 |   |
| Annual growth rate (%)  |     |       |   |     |       |       |     |       | 5,873 | % |     |       |    205 | % |     |       |     77 | % |     |       |     63 | % |     |       |     40 | % |     |       |     20 | % |     |       |     10 | % |     |       |      5 | % |

The list below provides a further explanation of the assumptions included in the Updated Projections: Revenue Assumptions •Regarding the revenue assumptions for Lumee Oxygen, Profusa’s management assumed that the Company will attain regulatory