Company: XXII
Filing Date: 2025-07-02
Form Type: 424B3
Source: 0001641172-25-017570
Chunk: 2

Company: 22nd Century Group, Inc.
Filing Date: 2025-07-02
Form: 424B3
Chunk 2
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 should not rely on it. We are not making offers to sell the securities in any jurisdiction in which an offer is not authorized or in which the person making that offer is not qualified to do so or to anyone to whom it is unlawful to make an offer. You should not assume that the information contained in this prospectus or any prospectus supplement or any other offering material, or the information we previously filed with the SEC that we incorporate by reference in this prospectus or any prospectus supplement, is accurate as of any date other than its respective date. Our business, financial condition, results of operations and prospects may have changed since those dates.

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<div align='center'>“Forward-Looking” Information</div>

This prospectus and the information incorporated by reference in this prospectus include “forward-looking statements” within the meaning of Section 27A of the Securities Act and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). All statements, other than statements of historical fact, included or incorporated by reference herein regarding our expectations, beliefs, plans, objectives, prospects, financial condition, assumptions or future events are forward-looking statements. You can identify these statements by words such as “aim,” “anticipate,” “assume,” “believe,” “could,” “due,” “estimate,” “expect,” “goal,” “intend,” “may,” “objective,” “plan,” “potential,” “positioned,” “predict,” “should,” “target,” “will,” “would” and other similar expressions that are predictions of or indicate future events and future trends. These forward-looking statements are based on current expectations, estimates, forecasts and projections about our business and the industry in which we operate and our management’s beliefs and assumptions. These statements are not guarantees of future performance or development and involve known and unknown risks, uncertainties and other factors that are in some cases beyond our control. All forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those that we expected, including the following summary of risk factors:

| ● | We                                                                                                                                    
 have had a history of losses and negative cash flows, and we may be unable to achieve and sustain profitability and positive cash     
 flows from operations.                                                                                                                |
| ● | Our                                                                                                                                   
 ability to continue as a going concern.                                                                                               |
| ● | Our                                                                                                                                   
 ability to maintain compliance with the NASDAQ listing requirements.                                                                  |
| ● | Our                                                                                                                                   
 competitors generally have