Company: RVRC
Filing Date: 2025-12-12
Form Type: S-1/A
Source: 0001213900-25-121070
Chunk: 2

Company: Revium Rx.
Filing Date: 2025-12-12
Form: S-1/A
Chunk 2
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 the resale by selling stockholders named therein of up to 37,625,790 shares (the “Shares”)          
 of our Common Stock (the “Resale Prospectus”). The registrant will not receive any proceeds from the sale of Common Stock     
 by the selling shareholders.                                                                                                  |

The Resale Prospectus is substantively identical
to the Public Offering Prospectus, except for the following principal points:

| ● | they contain different outside and inside front covers     
 and back covers;                                           |
| ● | they contain different Offering sections in the Prospectus 
 Summary section beginning on page 1;                       |
| ● | they contain different Use of Proceeds sections on         
 page 31;                                                   |
| ● | the Selling Stockholders section is included in the        
 Resale Prospectus;                                         |
| ● | the Plan of Distribution section on Alt-7 is inserted;     
 and                                                        |
| ● | the Capitalization and Dilution section is deleted         
 in the Resale Prospectus.                                  |

The Registrant has included in this Registration
Statement a set of alternate pages after the back-cover page of the Public Offering Prospectus (the “Alternate Pages”)
to reflect the foregoing differences in the Resale Prospectus as compared to the Public Offering Prospectus. The Public Offering Prospectus
will exclude the Alternate Pages and will be used for the public offering by the Registrant. The Resale Prospectus will be substantively
identical to the Public Offering Prospectus except for the addition or substitution of the Alternate Pages and will be used for the resale
offering by the Selling Stockholders.

For additional information on the possible methods
of sale that may be used by the Selling Stockholders, you should refer to the section of this Resale Prospectus entitled “Selling Stockholders—Plan of Distribution”.

The information in this prospectus is not complete and may be changed. We may not sell these securities until the registration statement filed with the Securities and Exchange Commission (the “SEC”) is declared effective. This prospectus is not an offer to sell these securities and is not soliciting an offer to buy these securities in any state or other jurisdiction where the offer or sale is not permitted.

| PRELIMINARY PROSPECTUS |     | SUBJECT       
 TO COMPLETION |     | DATED           
 ______ __, 2025 |

<div align='center'>Revium Rx.

Up to 1,562,500 Units to be sold by the Company,

Each Unit consisting of:

Two Shares of Common Stock and