Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 36

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 36
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 and stockholders of DiamiR will sign a stockholders agreement (“Stockholders Agreement”), which will be effective
until the earlier of (i) twelve (12) months following the date thereof and (ii) the date on which the stockholders of DiamiR
beneficially own, in the aggregate, a number of shares of common stock of the Combined Company equal to at least 25% of the then outstanding
shares of the Combined Company (such beneficial ownership, the “DiamiR Stockholders Beneficial Ownership”; such period, the
“Appointment Period”). The parties agree that, during the Appointment Period, they will take all necessary actions to cause
the number of directors at the Board of the Combined Company to be fixed at five (5). In addition, Kira S. Sheinerman, the co-founder
and a stockholder of DiamiR, and her affiliates (“DiamiR Primary Stockholder Parties”) will have the right to appoint two
(2) designees (each designee, the “Primary Stockholder Designee”, collectively, the “Primary Stockholder Designees”)
for nomination and election to the Board of Combined Company, and at least one (1) designee shall satisfy the independence requirements
of Rule 5605(c)(2)(A) of the Nasdaq listing rules, provided that the DiamiR Stockholders Beneficial Ownership is not less than
36%, and the DiamiR Primary Stockholder Parties will have the right to appoint one (1) director nominee to the Board of Combined
Company, provided that the DiamiR Stockholders Beneficial Ownership is no less than 25%.

For the election of directors
of the Combined Company: (1) each stockholder of DiamiR, who is a party to the Stockholders Agreement, will agree to vote all of
its shares of the Combined Company in favor of each Primary Stockholder Designee; (2) with respect to the election of nominees who
are not Primary Stockholder Designees, (a) until Aptorum’s 2027 annual stockholders meeting (the “2027 Meeting”),
each stockholder of DiamiR, who is a party to the Stockholders Agreement, will agree to vote all of its shares of the Combined Company
in accordance with the recommendations of the nominating and governance committee of the Board of the Combined Company; and (b) beginning
at the 2027 Meeting and at each annual meeting thereafter: (i) each stockholder of D