Company: TYRA
Filing Date: 2025-04-18
Form Type: DEF 14A
Source: 0001193125-25-085709
Chunk: 47

Company: Tyra Biosciences, Inc.
Filing Date: 2025-04-18
Form: DEF 14A
Chunk 47
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 our calendar years beginning 2025 and continuing through 2031 by the |

30

| number of shares equal to the lesser of (i) 1% of the total outstanding shares of our Common Stock as of the immediately preceding December 31 and (ii) such smaller number of shares as determined by our Board. |

Security Ownership of Certain Beneficial Owners and Management The following table and accompanying footnotes set forth certain information with respect to the beneficial ownership of our Common Stock at March 31, 2025 for:

| • |     | each of our directors; |

| • |     | each of our Named Executive Officers; |

| • |     | all of our current directors and executive officers as a group; and |

| • |     | each period, or group of affiliated persons, who beneficially owned more than 5% of our outstanding Common Stock. |

We have determined beneficial ownership in accordance with the rules of the SEC, and the information is not necessarily indicative of beneficial ownership for any other purpose. Except as indicated by the footnotes below, we believe, based on information furnished to us, that the persons and entities named in the table below have sole voting and sole investment power with respect to all shares of Common Stock that they beneficially owned, subject to applicable community property laws. Applicable percentage ownership is based on 53,089,957 shares of Common Stock outstanding as of March 31, 2025. In computing the number of shares of Common Stock beneficially owned by a person and the percentage ownership of that person, we deemed to be outstanding all shares of Common Stock subject to options, warrants or other rights held by that person or entity that are currently exercisable within 60 days of March 31, 2025. We did not deem these shares outstanding, however, for the purpose of computing the percentage ownership of any other person. Unless otherwise indicated, the address of each beneficial owner listed in the table below is c/o Tyra Biosciences, Inc., 2656 State Street, Carlsbad, California 92008.

|                                                                           |     | Shares Beneficially Owned |            |     |            |      |   |
| Beneficial Owner                                                          |     | Number                    |            |     | Percentage |      |   |
| 5% or Greater Stockholders                                                |     |                           |            |     |            |      |   |
| Entities affiliated with RA Capital Healthcare Fund, L.P. (1)             |     |                           | 10,