Company: CSTL
Filing Date: 2025-04-09
Form Type: DEF 14A
Source: 0001447362-25-000054
Chunk: 60

Company: CASTLE BIOSCIENCES INC
Filing Date: 2025-04-09
Form: DEF 14A
Chunk 60
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ified validation study achieved            
 •Specified electronic ordering metrics achieved 
 •Specified reimbursement rates achieved         |     |  25.0 | %                |     |  20.0 | %                | -2 |
|                       |     |                                                                |     |                                                |     |                                                 |     | 100.0 | %                |     | 128.8 | %                |    |

(1) The Compensation Committee used a sliding scale of revenue performance ranging from $283.0 million to $357.0 million to determine the actual weighting. The Compensation Committee used a sliding scale rather than a fixed threshold in order to better align the actual bonus payouts to the actual level of revenues, given the wide range of possible results. All points on this scale represent an increase in revenue performance from the prior year. The actual revenue for 2024 was $332.1 million. For illustration purpose, only the maximum, actual, target and minimum on the sliding scale of revenue is displayed.

#### 58Castle Biosciences 2025 Proxy Statement

#### Compensation Discussion and Analysis
|         |     |        |     | 2024 Revenue 
 ($ millions) |     |    | Growth over  
 2023 Revenue 
 of $220M     |     |     | Factor for   
 Pool Funding 
 (A)          |     |    | Target    
 Weighting 
 (B)       |     |       | Actual Weight for 
 Revenue Component 
 (A x B)           |
| Maximum |     |        |     |      $357.00 |     | 62 | %            |     | 150 | %            |     | 75 | %         |     | 112.5 | %                 |
|         |     | Actual |     |      $332.10 |     | 51 | %            |     | 145 | %            |     | 75 | %         |     | 108.8 | %                 |
| Target  |     |        |     |      $305.00 |     | 39 | %            |     | 100 | %            |     | 75 | %         |     |  75.0 | %                 |
| Minimum |     |        |     |      $283.00 |     | 29 | %            |     |  50 | %            |     | 75 | %         |     |  37.5 | %                 |

(2) Actual weighting could have