Company: RCUS
Filing Date: 2025-02-18
Form Type: 424B5
Source: 0001193125-25-028669
Chunk: 56

Company: Arcus Biosciences, Inc.
Filing Date: 2025-02-18
Form: 424B5
Chunk 56
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 relating to covenant defeasance and legal defeasance; |

| • |     | additions to or changes in the provisions relating to satisfaction and discharge of the indenture; |

| • |     | additions to or changes in the provisions relating to the modification of the indenture both with and without the 
 consent of holders of debt securities issued under the indenture;                                                 |

| • |     | the currency of payment of debt securities if other than U.S. dollars and the manner of determining the 
 equivalent amount in U.S. dollars;                                                                      |

15

| • |     | whether interest will be payable in cash or additional debt securities at our or the holders’ option and the 
 terms and conditions upon which the election may be made;                                                    |

| • |     | the terms and conditions, if any, upon which we will pay amounts in addition to the stated interest, premium, if                            
 any and principal amounts of the debt securities of the series to any holder that is not a “United States person” for federal tax purposes; |

| • |     | any restrictions on transfer, sale or assignment of the debt securities of the series; and |

| • |     | any other specific terms, preferences, rights or limitations of, or restrictions on, the debt securities, any                                              
 other additions or changes in the provisions of the indenture, and any terms that may be required by us or advisable under applicable laws or regulations. |

Conversion or Exchange Rights We will set forth in the applicable prospectus supplement the terms on which a series of debt securities may be convertible into or exchangeable for our common stock or our other securities. We will include provisions as to settlement upon conversion or exchange and whether conversion or exchange is mandatory, at the option of the holder or at our option. We may include provisions pursuant to which the number of shares of our common stock or our other securities that the holders of the series of debt securities receive would be subject to adjustment. Consolidation, Merger or Sale Unless we provide otherwise in the prospectus supplement applicable to a particular series of debt securities, the indenture will not contain any covenant that restricts our ability to merge or consolidate, or sell, convey, transfer or otherwise dispose of our assets as an entirety or substantially as an entirety. However, any successor to or acquirer of such assets (other than a subsidiary of ours) must assume all of our obligations under the indenture or the debt securities, as appropriate. Events of Default under the Indenture Unless we provide otherwise in the