Company: PRTA
Filing Date: 2025-03-28
Form Type: DEF 14A
Source: 0001559053-25-000017
Chunk: 92

Company: PROTHENA CORP PUBLIC LTD CO
Filing Date: 2025-03-28
Form: DEF 14A
Chunk 92
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 2024 of all other employees was $369,174 .

We calculated this median employee's total compensation for 2024 using the same methodology used to calculate our Chief Executive Officer’s total compensation for 2024, as set forth in the Summary Compensation Table - Fiscal Year 2024 above. The median employee's total compensation for 2024 included salary, an annual cash bonus paid in 2025 for 2024, stock option awards in 2024, and Company contributions in 2024 to that employee's account under our tax-qualified 401(k) defined contribution plan, each calculated for purposes of this pay ratio on the same basis as those same compensation elements of our Chief Executive Officer as explained in footnotes 1, 2, and 3 of the Summary Compensation Table - Fiscal Year 2024 . We believe that our Chief Executive Officer-to-median employee pay ratio is a reasonable estimate and was calculated in accordance with SEC regulations.

In order to identify the Company’s median employee, we used the base salary or wages (based on our

payroll records) earned from January 1 through September 30, 2024, for each employee who was employed as of October 1, 2024. We included all of our full-time, part-time, temporary, and seasonal employees, globally, but excluded our Chief Executive Officer. For permanent full- and part-time employees who were hired after January 1, 2024, or who were on an unpaid leave of absence during a part of 2024, we adjusted their salaries or wages to reflect what they would have earned had they worked the entire nine-month period through September 30, 2024.

We believe that this use of salary or wages earned through the first nine months of 2024 is an appropriate and consistently applied compensation measure for purposes of identifying the median employee from a compensation standpoint because all employees were eligible for annual cash bonuses and received stock option awards in 2024 and the distribution of cash bonuses and option awards were generally consistent with annual base pay. Earnings of our employees outside the U.S. were converted to U.S. dollars using an average currency exchange rate over the nine-month measurement period. We did not make any cost-of-living adjustments.

| 2025 PROXY STATEMENT |     | 55 |

#### TABLE OF CONTENTS
| Pay Versus Performance |

The following table sets forth information regarding the Company’s performance and the “compensation actually paid” to our named executive officers, as calculated in accordance