Company: PHAT
Filing Date: 2025-04-03
Form Type: S-8
Source: 0001193125-25-072460
Chunk: 1

Company: Phathom Pharmaceuticals, Inc.
Filing Date: 2025-04-03
Form: S-8
Chunk 1
---
 granted under the above-named plan are granted, exercised and/or distributed.

EXPLANATORY NOTE This registration statement registers the offer and sale of 2,500,000 shares of common stock of Phathom Pharmaceuticals, Inc. for issuance under the 2025 Employment Inducement Incentive Award Plan (the “2025 Plan”). PART I INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS The documents containing the information specified in Part I of Form S-8will be sent or given to participants as specified by Rule 428(b)(1) of the Securities Act. These documents and the documents incorporated by reference into this registration statement pursuant to Item 3 of Part II of this registration statement, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act. PART II INFORMATION REQUIRED IN THE REGISTRATION STATEMENT In this registration statement, Phathom Pharmaceuticals, Inc. is sometimes referred to as “Registrant,” “we,” “us” or “our.” Item 3. Incorporation of Documents by Reference. The SEC allows us to “incorporate by reference” the information we file with them, which means that we can disclose important information to you by referring you to those documents. The information incorporated by reference is considered to be part of this registration statement, and later information filed with the SEC will update and supersede this information. We hereby incorporate by reference into this registration statement the following documents previously filed with the SEC:

| (c) | the description of the Registrant’s common stock set forth in the Registrant’s registration statement                                                                                                                             
 on Form 8-A12B (Registration No. 001-39094), filed by the                                                                                                                                                                         
 Registrant with the SEC under Section 12(b) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), on October 16, 2019, including any amendments or reports filed for the purpose of updating such description. |

In addition, all documents filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act subsequent to the filing of this registration statement and prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which de-registersall securities then remaining unsold shall be deemed to be incorporated by reference into this registration statement and to be a part hereof from the date of filing such documents, except as to specific sections of such statements as set forth