Company: HURA
Filing Date: 2025-12-10
Form Type: 424B5
Source: 0001193125-25-313799
Chunk: 37

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-12-10
Form: 424B5
Chunk 37
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The holders of not less than a majority in aggregate principal amount of any series of debt securities, by notice to the trustee for that series, may waive, on behalf of the holders of all debt securities of that series, any past default or event of default with respect to that series and its consequences. A default or event of default in the payment of the principal of, or premium or interest on, any debt security and certain other defaults may not, however, be waived. Modification of the Indentures We, as well as the trustee for a series of debt securities, may enter into one or more supplemental indentures, without the consent of the holders of any of the debt securities, in order to:

| • |     | evidence the succession of another corporation to us and the assumption of our covenants by a successor; |

| • |     | add to our covenants or surrender any of our rights or powers; |

| • |     | add additional events of default for any series; |

| • |     | add, change or eliminate any provision affecting debt securities that are not yet issued; |

| • |     | secure the debt securities; |

| • |     | establish the form or terms of debt securities not yet issued; |

| • |     | evidence and provide for successor trustees; |

| • |     | add, change or eliminate any provision affecting registration as to principal of debt securities; |

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| • |     | permit the exchange of debt securities; |

| • |     | change or eliminate restrictions on payment in respect of debt securities; |

| • |     | change or eliminate provisions or add any other provisions that are required or desirable in accordance with any                                                                                                       
 amendments to the Trust Indenture Act, on the condition that this action does not adversely affect the interests of any holder of debt securities of any series issued under the indenture in any material respect; or |

| • |     | cure any ambiguity or correct any mistake. |

In addition, with the consent of the holders of not less than a majority in aggregate principal amount of the outstanding debt securities of all series affected by the supplemental indenture, we and the trustee may execute supplemental indentures adding any provisions to or changing or eliminating any of the provisions of the applicable indenture or any supplemental indenture or modifying the rights of the holders of debt securities of that series. No such supplemental indenture may, however, without the consent of the holder of each debt security that is affected:

| • |     |