Company: ACHV
Filing Date: 2025-01-10
Form Type: S-8
Source: 0000950170-25-004143
Chunk: 0

Company: ACHIEVE LIFE SCIENCES, INC.
Filing Date: 2025-01-10
Form: S-8
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission on January 10, 2025</div>

Registration No. 333-

<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM S-8

REGISTRATION STATEMENT

UNDER THE

SECURITIES ACT OF 1933

ACHIEVE LIFE SCIENCES, INC.

(Exact name of Registrant as specified in its charter)</div>

| Delaware                                                      |     | 95-4343413                            |
| (State or other jurisdiction ofincorporation or organization) |     | -I.R.S. EmployerIdentification Number |

| 22722 29th Drive SE, Suite 100Bothell, WA          |     98021 |
| 1040 West Georgia, Suite 1030Vancouver, BC, Canada |   V6E 4H1 |
| (Address of principal executive offices)           | -Zip Code |

<div align='center'>2018 Equity Incentive Plan

2017 Employee Stock Purchase Plan

(Full title of the plan)

Richard Stewart

Chief Executive Officer

22722 29th Drive SE, Suite 100

Bothell, WA 98021

(Name and address of agent for service)

(604) 210-2217

(Telephone number, including area code, or agent for service)

Please send copies of all communications to:

Alan Smith, Esq.

Amanda Rose, Esq.

Chelsea Anderson, Esq.

Fenwick & West LLP

401 Union Street, 5th Floor

Seattle, WA 98101

(206) 389-4510</div>

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

| Large accelerated filer |     | ☐ |     | Accelerated filer         |     | ☐ |
| Non-accelerated filer   |     | ☒ |     | Smaller reporting company |     | ☒ |
|                         |     |   |     | Emerging growth company   |     | ☐ |

If an emerging growth company, indicate