Company: FR
Filing Date: 2025-08-21
Form Type: 424B5
Source: 0000921825-25-000095
Chunk: 3

Company: FIRST INDUSTRIAL REALTY TRUST INC
Filing Date: 2025-08-21
Form: 424B5
Chunk 3
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<div align='center'>____________________________________________________________________________________________________________</div>

Investing in our common stock involves risks that are described in the “

#### Risk factors

#### ” section beginning on page

#### S-4
of this prospectus supplement and certain risks set forth under the caption “Item 1A. Risk Factors” included in our most recent Annual Report on Form 10-K filed with the Securities and Exchange Commission, which is incorporated by reference herein.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus. Any representation to the contrary is a criminal offense.

<div align='center'>____________________________________________________________________________________________________________</div>

#### Wells Fargo Securities

#### BofA Securities

#### BTIG

#### Citigroup

#### Fifth Third Securities

#### Jefferies

#### J.P. Morgan

#### RBC Capital Markets

#### Regions Securities LLC

#### Ramirez & Co., Inc.
<div align='center'>The date of this prospectus supplement is August 21, 2025</div>

### TABLE OF CONTENTS

#### Prospectus Supplement
|                                                      |     |      |     | Page |
| About This Prospectus Supplement and the Prospectus  |     | S-1  |     |      |
| Prospectus Supplement Summary                        |     | S-2  |     |      |
| Risk Factors                                         |     | S-4  |     |      |
| Cautionary Note Regarding Forward-Looking Statements |     | S-8  |     |      |
| Use of Proceeds                                      |     | S-9  |     |      |
| Supplemental U.S. Federal Income Tax Considerations  |     | S-9  |     |      |
| Plan of Distribution                                 |     | S-10 |     |      |
| Documents Incorporated by Reference                  |     | S-14 |     |      |
| Legal Matters                                        |     | S-15 |     |      |
| Experts                                              |     | S-15 |     |      |

#### Prospectus
|                                                                         |     |    |     | Page |
| ABOUT THIS PROSPECTUS                                                   |     |  1 |     |      |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS                    |     |  2 |     |      |
| THE COMPANY AND THE OPERATING PARTNERSHIP                               |     |  4 |     |      |
| RISK