Company: NCNA
Filing Date: 2025-07-16
Form Type: F-6 POS
Source: 0001193805-25-001028
Chunk: 5

Company: NuCana plc
Filing Date: 2025-07-16
Form: F-6 POS
Chunk 5
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 Form F-6 in Spring Branch, Texas, on July 16, 2025.

| NUCANA, INC. |                       |
| By:          | /s/ Jeffrey D. Bloss  |
| Name:        | Jeffrey D. Bloss      |
| Title:       | Chief Medical Officer |

<div align='center'>II-6</div>

| Exhibit | Document                                                          | Sequentially  
 Numbered Page |
| (a)(i)  | Form of Amendment No. 1 to Amended and Restated Deposit Agreement |               |
| (a)(ii) | Amended and Restated Deposit Agreement                            |               |

<div align='center'>II-7</div>