Company: SCLXW
Filing Date: 2025-09-29
Form Type: 424B3
Source: 0001193125-25-221022
Chunk: 66

Company: Scilex Holding Co
Filing Date: 2025-09-29
Form: 424B3
Chunk 66
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 Datavault. Additionally, the Pre-Funded Warrant includes the right to acquire any rights to purchase Datavault Common Stock, warrants or other
securities on the same terms as holders of Datavault Common Stock in such amount that the holder would have been

2

entitled to if the Pre-FundedWarrant were exercised. The Pre-FundedWarrant also includes the right to receive any dividends declared by Datavault. The Datavault SPA contains customary representations, warranties, covenants and agreements by the Company and Datavault and customary conditions to closing. The Datavault Shares, the Pre-FundedWarrant and the shares of Datavault Common Stock issuable upon exercise thereof are being offered by Datavault pursuant to a “shelf” registration statement on Form S-3(File No. 333-288538),as amended, which was originally filed with the SEC on July 7, 2025, and declared effective by the SEC on July 9, 2025. The foregoing summary of the Datavault SPA does not purport to be complete and is qualified in its entirety by reference to the full text of the Datavault SPA, a copy of which is filed herewith as Exhibit 10.1 and is incorporated herein by reference. Item 2.01. Completion of Acquisition or Disposition of Assets The information provided in Item 1.01 regarding the Datavault SPA is hereby incorporated by reference. Item 7.01. Regulation FD Disclosure. On September 25, 2025, the Company issued a press release announcing the execution of the Datavault SPA. A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-Kand is incorporated herein by reference. On September 26, 2025, the Company issued a press release announcing the closing of the transactions contemplated by the Datavault SPA. A copy of the press release is attached as Exhibit 99.2 to this Current Report on Form 8-Kand is incorporated herein by reference. The information in Item 7.01 of this Current Report on Form 8-K (including Exhibit99.1 and Exhibit 99.2 attached hereto) is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liabilities of that section, nor shall they be deemed incorporated by reference into any filing by the Company, under the Securities Act of 1933,