Company: AZN
Filing Date: 2025-09-29
Form Type: 6-K
Source: 0001104659-25-094039
Chunk: 14

Company: ASTRAZENECA PLC
Filing Date: 2025-09-29
Form: 6-K
Chunk 14
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 for one basis (

#### “AstraZeneca DRs”
). Affiliate Shareholders will be notified of their designation as such and will be contacted separately regarding these changes.

Further details of these arrangements are set out in Part III ( Settlement and Dealings in AstraZeneca Shares following the Settlement System Migration ) of this document.

#### AstraZeneca ADSs
At the Effective Time, the ADR Programme and the current listing of AstraZeneca ADSs on Nasdaq will be terminated. All AstraZeneca ADSs which remain issued and outstanding thereunder at the Effective Time will be cancelled in exchange for the right to receive or direct delivery of the number of AstraZeneca Shares they represent. Following such cancellation, AstraZeneca Shares (other than Affiliate Shares underlying AstraZeneca ADSs) will be transferred: (i) in the case of uncertificated AstraZeneca ADS, to the DTC Nominee; or (ii) in the case of registered AstraZeneca ADSs, transferred into a temporary election agent facility within DTC to be held by the Election Agent during a specified Holding Period, during which such holders of registered AstraZeneca ADSs may elect how their interest in AstraZeneca Shares shall be held going forward, provided that in each case, where holdings of AstraZeneca ADSs cannot be exchanged for an exact number of AstraZeneca Shares, fractions will be aggregated and sold in the open market with the net cash proceeds from the sale thereof being distributed to any holders entitled thereto. As a result of these changes, holders of AstraZeneca ADSs will be able to trade their AstraZeneca Shares directly on the NYSE following the Effective Time.

Further details are set out in paragraph 2(e) ( AstraZeneca Shares represented by AstraZeneca ADSs ) of Part III ( Settlement and Dealings in AstraZeneca Shares following the Settlement System Migration ) of this document.

**Holders of AstraZeneca Shares traded on Nasdaq Stockholm**

At the Effective Time, AstraZeneca Shares (other than Affiliate Shares) traded on Nasdaq Stockholm will be transferred to the DTC Nominee and deposited with DTC. Euroclear Bank SA/NV, an affiliate of Euroclear Sweden and an existing DTC participant, will hold the DTC book-entry interests in respect of such AstraZeneca Shares as custodian for Euroclear Sweden. Holders of such AstraZeneca Shares will have their