Company: JPC
Filing Date: 2025-06-12
Form Type: 424B3
Source: 0001999371-25-007638
Chunk: 5

Company: Nuveen Preferred & Income Opportunities Fund
Filing Date: 2025-06-12
Form: 424B3
Chunk 5
---
 such as a       
 bank or broker, you must register in advance to attend the Meetings virtually on the        
 Internet.                                                                                   |

To register to attend the Meetings online by webcast you must submit proof of your proxy power (legal proxy) reflecting your Fund holdings along with your name and email address to Computershare Fund Services. You must contact the bank or broker who holds your shares to obtain your legal proxy. Requests for registration must be labeled as “Legal Proxy” and be received no later than 5:00 p.m., Eastern Time, three business days prior to the meeting date.

You will receive a confirmation of your registration by email after we receive your registration materials.

Requests for registration should be directed to us by emailing an image of your legal proxy to shareholdermeetings@computershare.com.

| Q. | Will               
 anyone contact me? |

| A. | You                                                                                     
 may receive a call from Computershare Fund Services, the proxy solicitor hired by your  
 Fund, to verify that you received your proxy materials, to answer any questions you may 
 have about the Merger proposal or election of the Board Members and to encourage you    
 to vote your proxy.                                                                     |

We recognize the inconvenience of the proxy solicitation process and would not impose on you if we did not believe that each matter being proposed was important. Once your vote has been registered with the proxy solicitor, your name will be removed from the solicitor’s follow-up contact list.

Your vote is very important. We encourage you as a shareholder to participate in your Fund’s governance by returning your vote as soon as possible. If enough shareholders fail to cast their votes, a Fund may not be able to hold its Meeting or the vote on the Merger proposal or the election of Board Members, and will be required to incur additional solicitation costs in order to obtain sufficient shareholder participation.

<div align='center'>vi

June 11, 2025

NUVEEN PREFERRED SECURITIES & INCOME OPPORTUNITIES FUND (JPI)

NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
TO BE HELD ON July 25, 2025

AND

NUVEEN PREFERRED & INCOME OPPORTUNITIES FUND (JPC)
(EACH, A “FUND” AND TOGETHER, THE “FUNDS”)

NOTICE OF SPECIAL MEETING OF SHAREHOLDERS
TO BE HELD ON July 25, 2025</div>

To the Shareholders:

Notice