Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119822
Chunk: 94

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 94
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 one or more of our product candidates. Defense of these claims, regardless of their merit, could involve substantial expenses and could be a substantial diversion of our valuable management and employee resources from our business. If we collaborate with third parties in the development of technology in the future, our collaborators may not properly maintain or defend our intellectual property rights or may use our proprietary information in such a way as to invite litigation that could jeopardize or invalidate our intellectual property or proprietary information or expose us to litigation or potential liability. Further, collaborators may infringe the intellectual property rights of third parties, which may expose us to litigation and potential liability. In the future, we may agree to indemnify our commercial collaborators against certain intellectual property infringement claims brought by third parties. Any claims of patent infringement asserted by third parties would be time-consuming and could:

| • |     | result in costly litigation; |

| • |     | divert the time and attention of our technical personnel and management; |

| • |     | cause development delays; |

| • |     | prevent us from commercializing our product candidates until the asserted patent expires or is held finally 
 invalid or not infringed in a court of law;                                                                 |

| • |     | require us to develop non-infringing technology, which may not be 
 possible on a cost-effective basis;                               |

| • |     | require us to pay damages to the party whose intellectual property rights we may be found to be infringing, which 
 may include treble damages if we are found to have been willfully infringing such intellectual property;          |

| • |     | require us to pay the attorney’s fees and costs of litigation to the party whose intellectual property 
 rights we may be found to be infringing; and/or                                                        |

| • |     | require us to enter into royalty or licensing agreements, which may not be available on commercially reasonable 
 terms, or at all.                                                                                               |

If we are sued for patent infringement, we would need to demonstrate that our products or methods either do not infringe the patent claims of the relevant patent or that the patent claims are invalid, and we may not be able to do either. Proving invalidity is difficult. For example, in the United States, proving invalidity requires a showing of clear and convincing evidence to overcome the presumption of validity enjoyed by issued patents. Even if we are successful in these proceedings, we may incur substantial costs and divert management’s time and attention in pursuing these proceedings, which could have a material adverse effect on us. If