Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 387

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 387
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 held by it. Marc Bistricer disclaims beneficial ownership of the shares held by Nomis Bay Ltd. except to the extent of his pecuniary interest, if any, in such shares. |

| (9) | Each of the selling stockholders                                                                                                           
 is affiliated with H.C. Wainwright & Co., LLC, a registered broker dealer with a registered address of H.C. Wainwright &                   
 Co., LLC, 430 Park Ave, 3rd Floor, New York, NY 10022, and has sole voting and dispositive power over the securities held. The number      
 of shares to be sold in this offering consists of Class A ordinary shares issuable upon exercise of placement agent warrants, which were   
 received as compensation for acting as placement agent. The selling stockholder acquired the placement agent warrants in the ordinary      
 course of business and, at the time the placement agent warrants were acquired, the selling stockholder had no agreement or understanding, 
 directly or indirectly, with any person to distribute such securities.                                                                     |

<div align='center'>223

PLAN OF DISTRIBUTION</div>

The Selling Securityholders
of the securities and any of their pledgees, assignees and successors-in-interest may, from time to time, sell any or all of its securities
covered hereby on the principal trading market or any other stock exchange, market or trading facility on which the securities are traded
or in private transactions. These sales may be at fixed or negotiated prices. The Selling Securityholders may use any one or more of the
following methods when selling securities:

| ● | ordinary brokerage transactions and transactions in which the broker-dealer solicits purchasers; |

| ● | block trades in which the broker-dealer will attempt to sell the securities as agent but may position and resell a portion of the block as principal to facilitate the transaction; |

| ● | purchases by a broker-dealer as principal and resale by the broker-dealer for its account; |

| ● | an exchange distribution in accordance with the rules of the applicable exchange; |

| ● | privately negotiated transactions; |

| ● | settlement of short sales; |

| ● | in transactions through broker-dealers that agree with the Selling Securityholders to sell a specified number of such securities at a stipulated price per security; |

| ● | through the writing or settlement of options or other hedging transactions, whether through an options exchange or otherwise; |

| ● | a combination of any such methods of sale; or |

| ● | any other