Company: TELO
Filing Date: 2025-11-20
Form Type: PREM14A
Source: 0001493152-25-024463
Chunk: 213

Company: Telomir Pharmaceuticals, Inc.
Filing Date: 2025-11-20
Form: PREM14A
Chunk 213
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, also called neovascularor advanced AMD, is less common but more severe. It can cause rapid and significant loss of vision. Any stage of dry AMD can progress to wet AMD, but wet AMD itself is always a late-stagecondition. It occurs when abnormal blood vessels grow beneath the retina and leak fluid or blood, leading to damage in the macula. The positive news is that effective treatments are available to help slow progression and preserve vision in many cases.

1 https://www.macularsociety.org/diagnosis-treatment/treatments/

2 https://www.fightingblindness.ca/eyehealth/eye-diseases/age-related-macular-degeneration/

| Moore Financial Consulting |

| Telomir Pharmaceuticals, Inc.Valuation | November 2025Page 7 of 24 |

Causes of AMD

Age-related macular degeneration (AMD) develops due to a combination of aging, genetic, and environmental factorsthat damage the macula, the small area in the retina responsible for central vision. The main causes and risk factors include:

Aging

| ● | The                                                                     
 most significant cause, the risk of AMD increases sharply after age 50. |
| ● | Over                                                                    
 time, the cells in the macula break down, leading to vision loss.       |

Genetics and Family History

| ● | Having                                                                
 a family history of AMD increases your risk.                          |
| ● | Certain                                                               
 genes (like CFH and ARMS2) have been linked to higher susceptibility. |

Smoking

| ● | Smoking                                                           
 doubles or even triples the risk of developing AMD.               |
| ● | It                                                                
 reduces blood flow and oxygen to the retina, accelerating damage. |

Poor Diet and Nutrition

| ● | Diets                                                                                    
 low in antioxidants (like vitamins C and E), zinc, lutein, and zeaxanthin can contribute 
 to macular damage.                                                                       |
| ● | High                                                                                     
 intake of saturated fats and processed foods increases risk.                             |

Sun Exposure

| ● | Long-term                                                     
 exposure to ultraviolet (UV) light may damage retinal tissue. |

Cardiovascular Factors

| ● | High                                                                                             
 blood pressure, high cholesterol, and obesity can affect blood vessels in the eye and contribute 
 to AMD.                                                                                          |

Other Risk Factors

| ● | Light-colored                                              
 eyes (which are more sensitive to sunlight)                |
| ● | Female                                                     
 gender (slightly higher prevalence)                        |
| ● |