Company: AZN
Filing Date: 2025-09-29
Form Type: 6-K
Source: 0001104659-25-094039
Chunk: 19

Company: ASTRAZENECA PLC
Filing Date: 2025-09-29
Form: 6-K
Chunk 19
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 please contact the DI Depositary by phone on 0370 707 1682 (from inside the UK) or +44 (0) 370 707 1682 (from outside the UK). Lines are open 8:30 a.m. to 5:30 p.m. (UK time), Monday to Friday (excluding public holidays in England and Wales).

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TABLE OF CONTENTS

The registered holder of AstraZeneca Shares represented by AstraZeneca DIs will be the DTC Nominee. The custodian of those AstraZeneca Shares will be the DI Custodian, which will hold the book entry interest in such AstraZeneca Shares through the DTC clearing system for the DI Depositary. The DI Depositary will hold the book entry interests in those AstraZeneca Shares on trust (as bare trustee under English law). The DI Depositary will maintain a register of holders of AstraZeneca DIs and will make such register accessible to AstraZeneca.

#### Rights attaching to AstraZeneca DIs
Under the DI Deed, the DI Depositary will: (a) send out notices of general meetings to the holders of AstraZeneca DIs; and (b) produce a definitive list of holders of AstraZeneca DIs at the record date for such general meetings. In addition, holders of AstraZeneca DIs will be entitled to provide voting instructions via the DI Depositary to the DI Custodian in respect of the underlying AstraZeneca Shares.

As a result, the holders of AstraZeneca DIs will be able to:

•

receive notices of general meetings of AstraZeneca;

•

give directions as to voting at general meetings of AstraZeneca;

•

request to be appointed as proxy in respect of AstraZeneca Shares underlying their AstraZeneca DIs, enabling them to attend and speak at general meetings of AstraZeneca; and

•

have made available to them, at their request, copies of the annual report and accounts of AstraZeneca and all other documents issued by AstraZeneca to Shareholders generally.

Holders of AstraZeneca DIs will otherwise be treated in the same manner as if they were registered holders of AstraZeneca Shares underlying their AstraZeneca DIs, so far as is possible in accordance with applicable law, the CREST arrangements and the DI Deed. This will include being able to receive