Company: PRTA
Filing Date: 2025-03-28
Form Type: DEF 14A
Source: 0001559053-25-000017
Chunk: 3

Company: PROTHENA CORP PUBLIC LTD CO
Filing Date: 2025-03-28
Form: DEF 14A
Chunk 3
---
 Executive Compensation                                            |     |   39 |
| Executive Compensation for Fiscal Year2024                                         |     |   41 |
| Employment and Severance Arrangements                                              |     |   43 |
| REPORT OF THE COMPENSATION COMMITTEE OF THE BOARD OF DIRECTORS                     |     |   44 |
| EXECUTIVE COMPENSATION                                                             |     |   45 |
| Summary Compensation Table - Fiscal Year2024                                       |     |   45 |
| Grants of Plan-Based Awards - Fiscal Year2024                                      |     |   46 |
| Outstanding Equity Awards at Fiscal Year-End - Fiscal Year2024                     |     |   47 |
| OptionExercisesand Stock Vested - Fiscal Year2024                                  |     |   49 |
| Potential Payments and Benefits upon Termination of Employment                     |     |   50 |
| Change in Control and Severance Arrangements                                       |     |   51 |
| Compensation Risk Assessment                                                       |     |   54 |
| Pay Ratio of Chief Executive Officer to Median Employee                            |     |   55 |
| Pay Versus Performance                                                             |     |   56 |
| EQUITY COMPENSATION PLAN INFORMATION                                               |     |   61 |
| TRANSACTIONS WITH RELATED PERSONS AND INDEMNIFICATION                              |     |   62 |
| HOUSEHOLDING OF PROXY MATERIALS                                                    |     |   63 |
| ANNUAL REPORT                                                                      |     |   63 |
| APPENDIXA- AMENDMENT TO THE PROTHENA CORPORATION PLC 2018 LONG TERM INCENTIVE PLAN |     |  A-1 |

#### TAB LE OF CONTENTS
| PROTHENA CORPORATION PLC |

#### Registered in Ireland - No. 518146

#### 77 Sir John Rogerson’s Quay, Block C, Grand Canal

#### Docklands, Dublin 2, D02 VK60, Ireland

### PROXY STATEMENT

### FOR THE ANNUAL GENERAL

### MEETING OF SHAREHOLDERS

#### TO BE HELD ON MAY 13, 2025

### GENERAL INFORMATION
The Board of Directors of Prothena Corporation plc is soliciting your proxy to vote at the Annual General Meeting of Shareholders to be held on Tuesday, May 13, 2025, at 4:00 p.m. local time, and any adjournment or postponement of that meeting (the “Annual Meeting”). The Annual Meeting will be held at