Company: XOMAP
Filing Date: 2025-10-03
Form Type: 424B5
Source: 0001193125-25-230383
Chunk: 32

Company: XOMA Royalty Corp
Filing Date: 2025-10-03
Form: 424B5
Chunk 32
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 Nevada law, by Brownstein Hyatt Farber Schreck, LLP, Las Vegas, Nevada. Leerink Partners LLC is being represented in connection with this offering by Duane Morris LLP, New York, New York.

EXPERTS

The financial statements of XOMA Royalty Corporation as of December 31, 2024 and 2023, and for each of the two years in the period ended
December 31, 2024, incorporated by reference in this prospectus supplement, have been audited by Deloitte & Touche LLP, an independent registered public accounting firm, as stated in their report. Such financial statements are
incorporated by reference in reliance upon the report of such firm given their authority as experts in accounting and auditing.

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WHERE YOU CAN FIND MORE INFORMATION

We are subject to the informational requirements of the Exchange Act and are required to file annual, quarterly and other reports, proxy statements and other
information with the SEC. The SEC maintains an Internet website (www.sec.gov) that contains reports, proxy and information statements, and various other information about registrants, like us, that file electronically with the
SEC.

Information about us is also available at our website at www.xoma.com. You may access these materials free of charge as soon as reasonably
practicable after they are electronically filed with, or furnished to, the SEC. However, the information on our website is not a part of this prospectus supplement and is not incorporated by reference into this prospectus supplement.

This prospectus supplement and the accompanying prospectus are part of the registration statement on Form S-3 we filed
with the SEC under the Securities Act and does not contain all the information set forth in the registration statement. Whenever a reference is made in this prospectus supplement to any of our contracts, agreements or other documents, the reference
may not be complete and you should refer to the exhibits that are part of the registration statement or the exhibits to the reports or other documents incorporated by reference into this prospectus supplement for a copy of such contract, agreement
or other document. You may review a copy of the registration statement through the SEC’s website or our website.

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INCORPORATION OF CERTAIN INFORMATION BY REFERENCE The SEC allows us to incorporate by reference information from other documents that we file with it, which means that we can disclose important information to you by referring you to those documents. The information incorporated by reference is considered to be part of this prospectus supplement and the