Company: RVRC
Filing Date: 2025-10-03
Form Type: S-1/A
Source: 0001213900-25-096094
Chunk: 248

Company: Revium Rx.
Filing Date: 2025-10-03
Form: S-1/A
Chunk 248
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                                                                                                           registrant hereby undertakes: |                                                                                                                                          |
|     |                                                                                                                                      -1 | That, for the purpose of                                                                                                                 
 determining any liability under the Securities Act, each post-effective amendment that contains a form of prospectus shall be deemed     
 to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall    
 be deemed to be the initial bona fide offering thereof.                                                                                  |
|     |                                                                                                                                      -2 | That, for purposes of determining                                                                                                        
 any liability under the Securities Act, the information omitted from the form of prospectus filed as part of this registration statement 
 in reliance upon Rule 430A and contained in a form of prospectus filed by the registrant pursuant to Rule 424(b)(1) or (4) or 497(h)     
 under the Securities Act shall be deemed to be part of this registration statement as of the time it was declared effective.             |

<div align='center'>II-3

SIGNATURES</div>

Pursuant to the requirements of the Securities
Act, the registrant has duly caused this registration statement to be signed on its behalf by the undersigned in the city of Herzliya,
Israel on October 3, 2025.

| REVIUM RX. |                                             |
| By         | /s/                                         
 Amir Avraham                                |
|            | Amir Avraham                                |
|            | Interim Chief Executive                     
 Officer                                     |
|            | -Principal Executive Officer                |
| By         | /s/                                         
 Arie Gordashnikov                           |
|            | Arie Gordashnikov                           |
|            | Chief Financial Officer                     |
|            | -Principal Financial and Accounting Officer |

<div align='center'>POWER OF ATTORNEY</div>

KNOW ALL PERSONS BY THESE PRESENTS, that each
person whose signature appears below hereby constitutes and appoints David Akunis, as his true and lawful attorney-in-fact and agent,
with full power of substitution and re-substitution, for him and in his name, place and stead in any and all capacities, in connection
with this Registration Statement, including to sign in the name and on behalf of the undersigned, this Registration Statement and any
and all amendments thereto, including post-effective amendments and registrations filed pursuant to Rule 462 under the U.S. Securities
Act of 1933, and to file the same, with all exhibits thereto, and other documents in connection