Company: FCNCB
Filing Date: 2025-03-06
Form Type: 424B5
Source: 0001193125-25-047965
Chunk: 18

Company: FIRST CITIZENS BANCSHARES INC /DE/
Filing Date: 2025-03-06
Form: 424B5
Chunk 18
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 of the subordinated notes, see “Material United States Federal Income Tax Considerations.” |

| Governing Law | The subordinated notes and the Subordinated Indenture pursuant to which we will issue the subordinated notes will be governed by the laws of the State of New York. |

| Trustee | U.S. Bank Trust Company, National Association |

| Calculation Agent | U.S. Bank Trust Company, National Association |

| Risk Factors | Investing in the subordinated notes involves risks. Potential investors are urged to read and consider the risk factors relating to an investment in the subordinated notes set forth under “Risk Factors” beginning on page S-11 of                     
 this prospectus supplement, as well as the risk factors and other information included or incorporated by reference in this prospectus supplement and the accompanying prospectus, for a discussion of factors that you should carefully consider before 
 deciding whether to invest in the subordinated notes.                                                                                                                                                                                                    |

S-10

RISK FACTORS

An investment in our notes involves certain risks. You should carefully consider the risks described below and the risk factors included in our Annual Report on Form 10-Kfor the year ended December 31, 2024, as well as the other information included or incorporated by reference in this prospectus supplement and the accompanying prospectus, before making an investment decision. Our business, financial condition or results of operations could be materially adversely affected by any of these risks. This prospectus supplement also contains forward-looking statements that involve risks and uncertainties. Our actual results could differ materially from those anticipated in any forward-looking statements as a result of certain factors, including the risks faced by us described below and elsewhere in this prospectus supplement and the accompanying prospectus.

The notes are BancShares’ obligations, not obligations of any of BancShares’ subsidiaries, and as such will be structurally subordinated to the claims of its subsidiaries’ creditors.

The notes are exclusively obligations of
BancShares and not those of its subsidiaries. BancShares is a bank holding company that conducts substantially all of its operations through its bank and non-bank subsidiaries. As a result, BancShares’
ability to make payments on the notes will depend primarily upon the receipt of dividends and other distributions from its subsidiaries. If BancShares does not receive sufficient cash dividends and other distributions from its subsidiaries, it is
unlikely that it will have sufficient funds to make payments on the notes.

BancShares’ subsidiaries are separate and distinct legal
entities. BancShares’ subsidiaries have no obligation to pay any amounts due on the