Company: SNY
Filing Date: 2025-10-27
Form Type: 424B5
Source: 0001193125-25-250786
Chunk: 10

Company: Sanofi
Filing Date: 2025-10-27
Form: 424B5
Chunk 10
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 40 00.

S-7

THE OFFERING Please refer to “Description of the Notes” on page S-23of this prospectus supplement and “Description of Debt Securities We May Offer” in the attached prospectus for more information about the notes.

| Issuer | Sanofi |

| Notes Offered | $   in principal amount of floating rate notes due 20   (the “20   floating rate notes”) |

| $   in principal amount of floating rate notes due 20 (the “20   floating rate notes”) |

| $   in principal amount of   % notes due 20   (the “20   fixed rate notes”) |

| $   in principal amount of   % notes due 20   (the “20   fixed rate notes”) |

| $   in principal amount of   % notes due 20   (the “20   fixed rate notes”) |

| In this prospectus supplement, we refer to the 20   floating rate notes and 20   floating rate notes collectively as the “floating rate notes”. We refer to the             
 20   fixed rate notes, the 20   fixed rate notes and the 20   fixed rate notes collectively as the “fixed rate notes.” The floating rate notes and the fixed rate notes are 
 collectively referred to as the “notes.”                                                                                                                                    |

PROVISIONS APPLICABLE TO THE FIXED RATE NOTES

| Maturity Date | 20   fixed rate notes:   , 20 |

| 20   fixed rate notes:   , 20 |

| 20   fixed rate notes:   , 20 |

| Interest Rate | The 20   fixed rate notes will bear interest from   , 2025 at a fixed rate of   % per annum. |

| The