Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 252

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 252
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) 670-0468               |     | if you are a Comerica stockholder:      
 Comerica Incorporated 1717              
 Main Street, MC 640s4 Dallas, TX 75201  
 Attn: Investor Relations (833) 571-0486 |

This document does not constitute an offer to sell, or a solicitation of an offer to purchase, the securities offered by this document, or the solicitation of a proxy, in any jurisdiction to or from any person to whom or from whom it is unlawful to make such offer, solicitation of an offer or proxy solicitation in such jurisdiction. Neither the delivery of this document nor any distribution of securities pursuant to this document shall, under any circumstances, create any implication that there has been no change in the information set forth or incorporated into this document by reference or in our affairs since the date of this document. The information contained in this document with respect to Fifth Third was provided by Fifth Third and the information contained in this document with respect to Comerica was provided by Comerica. 180

ANNEX A

AGREEMENT AND PLAN OF MERGER

by and among

FIFTH THIRD BANCORP,

FIFTH THIRD FINANCIAL CORPORATION,

COMERICA INCORPORATED

and

COMERICA HOLDINGS INCORPORATED

Dated as of October 5, 2025

TABLE OF CONTENTS

| ARTICLE I THE MERGERS                                 |     |                                                    |     | A-1  |
| 1.1.                                                  |     | Merger                                             |     | A-1  |
| 1.2.                                                  |     | Time and Place of Closing                          |     | A-1  |
| 1.3.                                                  |     | Effective Time                                     |     | A-2  |
| 1.4.                                                  |     | Conversion of Common Stock                         |     | A-2  |
| 1.5.                                                  |     | Conversion of Preferred Stock                      |     | A-3  |
| 1.6.                                                  |     | Fifth Third Common Stock                           |     | A-3  |
| 1.7.                                                  |     | Fifth Third Intermediary Common Stock              |     | A-3  |
| 1.8.                                                  |     | Treatment of Comerica Equity Awards                |     | A-3  |
| 1.9.                                                  |     | Articles of Incorporation of Surv