Company: PRME
Filing Date: 2025-04-22
Form Type: DEF 14A
Source: 0001628280-25-018704
Chunk: 65

Company: Prime Medicine, Inc.
Filing Date: 2025-04-22
Form: DEF 14A
Chunk 65
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. Mr. Cahill, a member of our board of directors, is the managing member of Newpath GP LLC.

The address of all entities and Mr. Cahill referenced in this footnote is 800 Boylston Street, Suite 2222, Boston, Massachusetts 02199.

(7) Consists of: (a) 2,310,837 shares of common stock held by Dr. Gottesdiener, (b) 627,440 shares of common stock underlying options exercisable within 60 days of March 31, 2025, (c) 50,241 shares of common stock held by Dr. Gottesdiener’s spouse, (d) 682,259 shares of common stock held by the Coolidge GST Trust-2022 (the “Coolidge Trust Shares”), and (e) 1,317,741 shares of common stock held by the Gottesdiener Family GST Trust (the “Gottesdiener Family Trust Shares”). Dr. Gottesdiener disclaims beneficial ownership of the Coolidge Trust Shares and the Gottesdiener Family Trust Shares.

(8) Consists entirely of shares of common stock underlying options exercisable within 60 days of March 31, 2025.

(9) Consists of: (a) 965,001 shares of common stock held by Dr. Duffield, and (b) 182,422 shares of common stock underlying options exercisable within 60 days of March 31, 2025.

(10) Includes 39,062 shares of common stock underlying options exercisable within 60 days of March 31, 2025.

(11) Consists of: (a) 39,062 shares of common stock underlying options exercisable within 60 days of March 31, 2025 and (b) 16,080 shares of common stock held by a trust for the benefit of Mr. Nelsen’s family members.

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### GENERAL MATTERS

#### Stockholder Proposals for 2026 Annual Meeting
Requirements for Stockholder Proposals to be Considered for Inclusion in our Proxy Materials. To be considered for inclusion in next year’s proxy statement, stockholder proposals pursuant to Rule 14a-8 under the Exchange Act must be received by our Secretary, at Prime Medicine, Inc. no later than December 23, 2025, which is 120 days prior to April 22, 2026. Stock