Company: SPRB
Filing Date: 2025-12-12
Form Type: 424B3
Source: 0001193125-25-317547
Chunk: 15

Company: SPRUCE BIOSCIENCES, INC.
Filing Date: 2025-12-12
Form: 424B3
Chunk 15
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i) 53,154 shares of common stock issued in the Private Placement and (ii) 24 shares of common stock issuable upon exercise of Pre-Funded Warrants purchased in the Private Placement, in each case held by ExodusPoint Partners Master Fund, LP. Such amount does not include 91,402 shares of common stock issuable upon exercise of Pre-Funded Warrants purchased by ExodusPoint Partners Master Fund, LP in the Private Placement. The Pre-Funded Warrants are subject to a beneficial ownership limitation of 4.99%, which limitation restricts ExodusPoint Partners Master Fund, LP from exercising that portion of the Pre-Funded Warrants that would result in ExodusPoint Partners Master Fund, LP and its affiliates owning, after exercise, a number of shares of common stock in excess of the beneficial ownership limitation. ExodusPoint Capital Management, LP acts as the investment manager to ExodusPoint Partners Master Fund, LP. Michael Gelband, the co-founder and chief executive officer of ExodusPoint Capital Management, LP and Hyung Lee (the other co-founder of ExodusPoint Capital Management, LP), have voting and investment control of the securities held by ExodusPoint Capital Management, LP. The address of ExodusPoint Partners Master Fund, LP is c/o ExodusPoint Capital Management, LP, 65 East 55th Street, 5th Floor, New York, NY 10022. (4) Consists of (i) 77,282 shares of common stock issued in the Private Placement and (ii) 32,417 shares of common stock issuable upon exercise of Pre-Funded Warrants purchased in the Private Placement, in each case held by Citadel CEMF Investments Ltd. Such amount does not include 301 shares of common stock issuable upon exercise of Pre-Funded Warrants purchased by Citadel CEMF Investments Ltd. in the Private Placement. The Pre-Funded Warrants are subject to a beneficial ownership limitation of 9.99%, which limitation restricts Citadel CEMF Investments Ltd. from exercising that portion of the Pre-Funded Warrants that would result in Citadel CEMF Investments Ltd. and its affiliates owning, after exercise, a number of shares of common stock in excess of the beneficial ownership limitation. Citadel Advisors LLC

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is the portfolio manager of Citadel CEMF Investments Ltd. Citadel Advisors Holdings LP, or CAH, is the sole member of Citadel Advisors LLC. Citadel GP LLC, or CGP, is the general partner of CAH. Kenneth Griffin