Company: AZN
Filing Date: 2025-03-12
Form Type: 6-K
Source: 0001654954-25-002669
Chunk: 1

Company: ASTRAZENECA PLC
Filing Date: 2025-03-12
Form: 6-K
Chunk 1
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 registered office (if applicable)

#### Country of registered office (if applicable)
**5. Date on which the threshold was crossed or reached**

| 10-Mar-2025 |

#### 6. Date on which Issuer notified
| 11-Mar-2025 |

**7. Total positions of person(s) subject to the notification obligation**

|                                                       |                                                  % 
 of voting rights attached to shares (total of 8.A) |                                                                % 
 of voting rights through financial instruments (total of 8.B 1 + 
                                                           8.B 2) |                    Total 
 of both in % (8.A + 8.B) |                                  Total 
 number of voting rights held in issuer |
| Resulting situation                                   
 on the date on which threshold was crossed or reached |                                           5.000629 |                                                         0.000000 |                 5.000629 |                               77540115 |
| Position of                                           
 previous notification (if applicable)                 |                                           4.996796 |                                                         0.000000 |                 4.996796 |                                        |

**8. Notified details of the resulting situation on the date on which the threshold was crossed or reached**

#### 8A. Voting rights attached to shares
| Class/Type of shares ISIN code(if possible) | Number of direct voting rights (DTR5.1) | Number of indirect voting rights (DTR5.2.1) | % of direct voting rights (DTR5.1) | % of indirect voting rights (DTR5.2.1) |
| GB0009895292 Common                         
 Stock                                       |                                         |                                    61618592 |                                    |                               3.973836 |
| US0463531089                                
 Depository Receipt                          |                                         |                                    15921523 |                                    |                               1.026793 |
| Sub                                         
 Total 8.A                                   |                                77540115 |                                             | 5.000629%                          |                                        |

**8B1. Financial Instruments according to (DTR5.3.1R.(1) (a))**

| Type of financial instrument | Expiration date | Exercise/conversion period | Number of voting rights that may be acquired if the instrument is 
 exercised/converted                                               | % of voting rights |
| Sub                          
 Total 8.B1                   |                 |                            |                                                                   |                    |

**8B2. Financial Instruments with similar economic effect according to (DTR5.3.