Company: TEM
Filing Date: 2025-02-24
Form Type: 10-K
Source: 0000950170-25-025603
Chunk: 106

Company: Tempus AI, Inc.
Filing Date: 2025-02-24
Form: 10-K
Item: Item 1
Chunk 106
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, our local partners to obtain regulatory approvals or certifications for the use of our products in various countries; 

•additional potentially blocking or relevant third-party patent or other intellectual property rights; 

•complexities and difficulties in obtaining intellectual property protection and maintaining and enforcing our intellectual property rights; 

•difficulties in staffing and managing foreign operations; 

•complexities associated with managing multiple payer reimbursement regimes, government payers, or patient self-pay systems; 

•logistics and regulations associated with shipping blood samples, including infrastructure conditions and transportation delays; 

•patient populations that are underrepresented in our databases; 

•limits in our ability to penetrate international markets if we are not able to perform our tests locally; 

•financial risks, such as longer payment cycles, difficulty collecting accounts receivable, the impact of local and regional financial crises on demand and payment for our products and exposure to foreign currency exchange rate fluctuations, currency controls and cash repatriation restrictions; 

•natural disasters, political and economic instability, including wars (such as the armed conflicts between Russia and Ukraine and the hostilities in the Middle East), terrorism, and political unrest, boycotts, curtailment of trade and other business restrictions; 

•public health or similar issues, such as epidemics or pandemics, that could cause business disruption; and 

•regulatory and compliance risks that relate to maintaining accurate information and control over sales and distributors’ activities that may fall within the purview of the U.S. Foreign Corrupt Practices Act, or FCPA, its books and records provisions, or its anti-bribery provisions. 

Any of these factors could significantly harm our future international expansion and operations and, consequently, our revenue and results of operations. 

74

Risks Related to Our Highly Regulated Industry 

We and the third parties with whom we work are subject to stringent and evolving U.S. and foreign laws, regulations, and rules, contractual obligations, industry standards, policies and other obligations related to data privacy and security. Our (or the third parties with whom we work) actual or perceived failure to comply with such obligations could lead to regulatory investigations or actions; litigation (including class claims) and mass arbitration demands; fines and penalties; disruptions of our business operations; reputational harm; loss of revenue or profits; and other adverse business consequences. 

In the ordinary course of business, we collect, receive, store, process, generate, use, transfer, disclose, make accessible, protect, secure, dispose of, transmit, and share (collectively