Company: BCDRF
Filing Date: 2025-01-08
Form Type: 424B5
Source: 0001193125-25-003514
Chunk: 330

Company: Banco Santander, S.A.
Filing Date: 2025-01-08
Form: 424B5
Chunk 330
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 will provide free of charge a copy of any or all of the documents that we incorporate by reference into this
prospectus, other than exhibits which are not specifically incorporated by reference into this prospectus. To obtain copies you should contact us at Investor Relations, Ciudad Grupo Santander, Avenida de Cantabria s/n, 28660 Boadilla del Monte,
Madrid, Spain (telephone: (011) 34-91-259-6520).

171

CAUTIONARY STATEMENT ON FORWARD-LOOKING STATEMENTS This prospectus, any accompanying prospectus supplement and the documents incorporated by reference into this prospectus contain statements that constitute “forward-looking statements” within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, information regarding:

| • |     | exposure to various types of market risks; |

| • |     | management strategy; |

| • |     | capital expenditures; |

| • |     | earnings and other targets; and |

| • |     | asset portfolios. |

Forward-looking statements may be identified by words such as “expect,” “project,” “anticipate,” “should,” “intend,” “probability,” “risk,” “VaR,” “RoRAC,” “RoRWA,” “TNAV,” “target,” “goal,” “objective,” “estimate,” “future” “commitment,” “commit,” “focus,” “pledge,” and similar expressions or by the use of similar expressions or variations on such expressions, or by the discussion of strategy or objectives. Forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and actual results may differ materially from those in the forward-looking statements. You should understand that the following important factors could affect our future results and could cause those results or other outcomes to differ materially from those anticipated in any forward-looking statement: Economic and Industry Conditions

| • |     | general economic or industry conditions in Spain, the U.K., the U.S., other European countries, Brazil, other 
 Latin American countries and the other areas where we have significant operations or investments;             |

| • |     | effects of the war in Ukraine or the covid-19 pandemic in the global 
 economy;                                                             |

| • |     | climate-related conditions, regulations, targets and weather events; |

| • |     | uncertainty over the scope of actions that may be required by us, governments and others to achieve goals                                                            
 relating to