Company: PTHS
Filing Date: 2025-08-28
Form Type: S-3
Source: 0001753926-25-001403
Chunk: 84

Company: Pelthos Therapeutics Inc.
Filing Date: 2025-08-28
Form: S-3
Chunk 84
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 align='center'>Pelthos Therapeutics Inc.
4020 Stirrup Creek Drive

Suite 110

Durham, NC 27703

(919) 908-2400</div>

Copies of these filings are also available on our website at https://pelthos.com.For other ways to obtain a copy of these filings, please refer to “Where You Can Find More Information” above.

<div align='center'>51

8,137,868 Common Shares

PROSPECTUS

The date of this prospectus is , 2025.</div>

We have not authorized any dealer, salesperson or other person to give any information or represent anything not contained in this prospectus. You must not rely on any unauthorized information. If anyone provides you with different or inconsistent information, you should not rely on it. This prospectus does not offer to sell any securities in any jurisdiction where it is unlawful. Neither the delivery of this prospectus, nor any sale made hereunder, shall create any implication that the information in this prospectus is correct after the date hereof.

<div align='center'>PART II - INFORMATION NOT REQUIRED IN PROSPECTUS</div>

Item 14. Other Expenses of Issuance and Distribution.

The following table sets forth an estimate of the fees and expenses relating to the issuance and distribution of the securities being registered hereby, other than underwriting discounts and commissions, all of which shall be borne by the registrant. All of such fees and expenses, except for the SEC registration fee, are estimated:

| SEC registration fee                           |     | $ | 26,400.78 |
| Transfer Agent and Registrar fees and expenses |     |   |         * |
| Legal fees and expenses                        |     |   |         * |
| Printing fees and expenses                     |     |   |         * |
| Accounting fees and expenses                   |     |   |         * |
| Miscellaneous fees and expenses                |     |   |         * |
| Total                                          |     |   |         * |

*These fees and expenses depend on the securities offered and the number of issuances and, accordingly, cannot be estimated at this time. An estimate of the aggregate expenses in connection with the sale and distribution of the securities being offered will be included in the applicable prospectus supplement.

Item 15. Indemnification of Officers and Directors.

Set forth below is a description of certain provisions of the registrant’s (the “Registrant” or “Company”) articles of incorporation (the “