Company: HURA
Filing Date: 2025-05-23
Form Type: 424B3
Source: 0001193125-25-125499
Chunk: 982

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-05-23
Form: 424B3
Chunk 982
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    8.4(ddd) |
| Superior Proposal                   |     |  5.4(f)(ii) |
| Surviving Company                   |     |    Recitals |
| Surviving Entity                    |     |    Recitals |
| Takeover Laws                       |     |        3.19 |
| Targeted Net Working Capital Amount |     |    8.4(eee) |
| Tax Return                          |     |    8.4(fff) |
| Taxes                               |     |    8.4(ggg) |
| Termination Fee                     |     |    8.4(hhh) |
| Trading Day                         |     |    8.4(iii) |
| Unpaid Company Transaction Expense  |     |    8.4(jjj) |
| WARN Act                            |     |     3.12(h) |
| Warrantholder Treatment Agreements  |     |      6.2(f) |

iv

FIRST AMENDMENT TO AGREEMENT AND PLAN OF MERGER

THIS FIRST AMENDMENT TO AGREEMENT AND PLAN OF MERGER (this “”), dated as of May 5, 2025, is made and entered
into by and among TuHURA Biosciences, Inc., a Nevada corporation (“”), Hura Merger Sub I, Inc., a Delaware corporation and direct wholly-owned Subsidiary of Parent (“”), Hura Merger Sub II, LLC, a
Delaware limited liability company and direct wholly-owned Subsidiary of Parent (“”, and together with Merger Sub I, the “”), Kineta, Inc., a Delaware corporation (the
“”), and Craig Philips, solely in his capacity as the representative, agent and attorney-in-fact of the stockholders of the Company (the
“”. Capitalized terms used but not otherwise defined herein shall have the meanings ascribed to them in the Merger Agreement (as defined below).

RECITALS

A.
WHEREAS, Parent, the Company, Merger Subs and the Stockholders Representative are parties to that certain Agreement and Plan of Merger, dated as of December 11, 2024 (the “”);

B. WHEREAS, of the Merger Agreement provides that the Merger Agreement may be amended, modified
or supplemented by a duly authorized instrument specifically designated as an amendment to the Merger Agreement and signed on behalf of each of the parties in interest at the time of such amendment; and

C. WHERE