Company: APM
Filing Date: 2025-07-22
Form Type: 6-K
Source: 0001213900-25-066642
Chunk: 17

Company: Aptorum Group Ltd
Filing Date: 2025-07-22
Form: 6-K
Chunk 17
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 be mailed to Aptorum’s shareholders as of a record date to be established for voting on the
proposed transactions. Shareholders will also be able to obtain copies of the notice, without charge, once available, at the
SEC’s website at www.sec.gov or by directing a request to: 17 Hanover Square, London W1S 1BN, United Kingdom, attention: Ian
Huen.

A registration statement relating to these securities will be filed
with the SEC and has not yet become effective. These securities may not be sold, nor may offers to buy be accepted, prior to the time
the registration statement becomes effective. This Form 6-K shall not constitute an offer to sell or the solicitation of an offer to buy,
nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful
prior to registration or qualification under the securities laws of any such state or jurisdiction. A copy of Aptorum’s registration
statement on Form S-4, once available, can be viewed on the SEC’s website.

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Financial Statements and Exhibits.

.

The following exhibits are attached.

| Exhibit 
 2.1     
 10.1    |     | Description                                                                                                                       
 Merger                                                                                                                            
 Agreement by and between Aptorum and DiamiR, dated July 14, 2025                                                                  
 Management                                                                                                                        
 Services Agreement by and between Aptorum Therapeutics and DiamiR, dated July 14, 2025                                            |
|:--------|:----|:----------------------------------------------------------------------------------------------------------------------------------|
| 10.2    |     | Intellectual Property License Agreement by and between Aptorum Therapeutics, Aptorum, DiamiR LLC, and DiamiR, dated July 14, 2025 |
| 10.3    |     | Voting and Support Agreement by and between Aptorum and its major shareholder, dated July 14, 2025                                |
| 10.4    |     | Form of Stockholders Agreement                                                                                                    |
| 99.1    |     | Press Release                                                                                                                     |

| * | Certain schedules have been omitted pursuant to Item 601(a)(5) of Regulation S-K. A copy of any omitted schedule will be furnished to the SEC upon request. |

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SIGNATURES</div>

Pursuant to the requirements
of the Securities Exchange Act of 1934, the registrant has duly caused