Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 263

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 263
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 |   |
| Accumulated deficit                                                                                                                                                                                                                                                                                      |     |   |     (124,958 | ) |     |   |     (115,728 | ) |
| Total stockholders’ deficit                                                                                                                                                                                                                                                                              |     |   |     (119,205 | ) |     |   |     (109,996 | ) |
| Total liabilities, convertible preferred stock and stockholders’ deficit                                                                                                                                                                                                                                 |     | $ |        3,073 |   |     | $ |        1,893 |   |

<div align='center'>The accompanying notes are an integral
part of these consolidated financial statements.

F-3

PROFUSA, INC. AND SUBSIDIARY
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
(IN THOUSANDS, EXCEPT SHARE AND PER SHARE AMOUNTS)</div>

|                                                                                                                                       |     | Year Ended   
 December 31, |      2024 |   |     |   |      2023 |   |
|:--------------------------------------------------------------------------------------------------------------------------------------|:----|:-------------|----------:|:--|:----|:--|----------:|:--|
| Government grant revenue                                                                                                              |     | $            |       100 |   |     | $ |        45 |   |
| Operating expenses:                                                                                                                   |     |              |           |   |     |   |           |   |
| Research and development                                                                                                              |     |              |     1,608 |   |     |   |     2,036 |   |
| General and administrative                                                                                                            |     |              |     2,992 |   |     |   |     4,079 |   |
| Total operating expenses                                                                                                              |     |              |     4,600 |   |     |   |     6,115 |   |
| Loss from operations                                                                                                                  |     |              |    (4,500 | ) |     |   |    (6,070 | ) |
| Other income (expenses)                                                                                                               |     |              |           |   |     |   |           |   |
| Loss on change in the fair value of related party Tasly convertible debt                                                              |     |              |      (311 | ) |     |   |       (22 | ) |
| Interest expense (including related parties amounts of $2,400 and $2,530 for the year ended December 31, 2024 and 2023, respectively)