Company: APM
Filing Date: 2025-10-14
Form Type: 424B5
Source: 0001213900-25-098635
Chunk: 67

Company: Aptorum Group Ltd
Filing Date: 2025-10-14
Form: 424B5
Chunk 67
---
 |     | US$              | 1.86 |     | US$   | 1,860,000 |

We have agreed to pay
the Placement Agent a cash fee equal to 7.0% of the aggregate gross proceeds of this offering. We will also pay the Placement Agent
in connection with this offering a management fee equal to 1.0% of the gross proceeds raised in the offering, $5,000 for
non-accountable expenses, $50,000 for expenses of legal counsel and other out-of-pocket expenses and $10,000 for clearing fees.
After deducting fees due to the Placement Agent and our estimated offering expenses, we expect the net proceeds from this offering
to be approximately US$1,725,000.

Placement Agent Warrants

We have agreed to issue to the Placement Agent,
or its designees, Placement Agent Warrants to purchase up to 60,000 Class A Ordinary Shares, which represents 6.0% of the aggregate number
of Class A Ordinary Shares purchased in this offering. The Placement Agent Warrants will have an exercise price equal to $2.50 per share,
or 125% of the offering price per ordinary share, and will expire on the earlier of (i) twenty-four months from the effective date of
a registration statement registering for resale the warrants and (ii) five years from the commencement of the sales pursuant to this offering.

<div align='center'>S-38</div>

Lock-up Agreements

The Company agreed pursuant
to the Securities Purchase Agreement that, subject to certain exceptions, for 30 calendar days following the closing of the Offering (the
“Standstill Period”), it would not (i) issue, or enter into any agreement to issue or announce the issuance or proposed issuance
of any Class A Ordinary Shares, or any securities of the Company or its subsidiaries which would entitle the holder thereof to acquire
at any time Class A Ordinary Shares (the “Ordinary Share Equivalents”), or (ii) file any registration statement or amendment
or supplement thereto. In addition, for one year following the closing of the Offering, subject to an exception, the Company is prohibited
from effecting or entering into an agreement to effect any issuance by the Company or any of its subsidiaries of Class A Ordinary Shares
or Ordinary Share Equivalents (or a combination of units thereof) involving a Variable Rate Transaction (as defined in the Securities
Purchase Agreement).

Each of our officers and directors
have agreed with the