Company: SXTPW
Filing Date: 2025-07-16
Form Type: 424B4
Source: 0001213900-25-064472
Chunk: 39

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-07-16
Form: 424B4
Chunk 39
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480 shares of Series A Preferred Stock. |

| (2) | Unless otherwise indicated,                      
 this prospectus supplement reflects and assumes: |

| ● | no exercise of the options                                                                    
 and warrants described above or the exercise of the Warrants or the Placement Agent Warrants. |

<div align='center'>18

RISK FACTORS</div>

Investing in our common stock involves a high degree of risk. You should carefully consider the risks described below, and those discussed under the section title “Risk Factors” contained in our Annual Report on Form 10-K for the year ended December 31, 2024, together with other information in this prospectus, the information and documents incorporated by reference herein, and in any free writing prospectus that we have authorized for use in connection with this offering. Our business is subject to many risks and uncertainties, which may affect our future financial performance. If any of the events or circumstances described below occur, our business and financial performance could be adversely affected, our actual results could differ materially from our expectations, and the price of our stock could decline. The risks and uncertainties discussed below are not the only ones we face. There may be additional risks and uncertainties not currently known to us or that we currently do not believe are material that may adversely affect our business and financial performance. The statements contained in this prospectus that are not historic facts are forward-looking statements that are subject to risks and uncertainties that could cause actual results to differ materially from those set forth in or implied by forward-looking statements. If any of the following risks actually occurs, our business, financial condition or results of operations could be harmed. In that case, the trading price of our common stock could decline, and investors in our securities may lose all or part of their investment.

Risks Related to this Offering and Ownership of Our Securities

This is a best-efforts offering, no minimum amount of securities is required to be sold and we may not raise the amount of capital we believe is required for our business plans.

The placement agent has agreed to use its reasonable
best efforts to solicit offers to purchase the securities being offered in this offering. The placement agent has no obligation to buy
any of the securities from us or to arrange for the purchase or sale of any specific number or dollar amount of the securities. There
is no required minimum number of securities or amount of proceeds that must be sold as a condition to completion of this offering. Because
there is no minimum offering amount required as a condition to the closing of this offering, the