Company: SCLXW
Filing Date: 2025-05-07
Form Type: POS AM
Source: 0001193125-25-115088
Chunk: 36

Company: Scilex Holding Co
Filing Date: 2025-05-07
Form: POS AM
Chunk 36
---
 an aggregate of up to 198,810 shares (on a post-Reverse Stock Split basis) of Common Stock, with an exercise price of $402.50 per whole share; |

| • |     | 108,686 shares of Common Stock issuable upon the exercise of the warrants to purchase shares of Common Stock, with an exercise price of $59.50 per share; |

| • |     | 13,446 shares of Common Stock issuable upon the exercise of the warrants to purchase shares of Common Stock, with an exercise price of $74.38 per share; |

| • |     | 428,572 shares of Common Stock issuable upon the exercise of the warrants to purchase shares of Common Stock, with an exercise price of $38.50 per share; |

| • |     | 34,286 shares of Common Stock issuable upon the exercise of the warrants to purchase shares of Common Stock, with an exercise price of $43.75 per share; |

| • |     | 319,132 shares of Common Stock issuable upon the exercise of the warrants to purchase shares of Common Stock, with a current exercise price of $36.40 per share; |

| • |     | 914,823 shares of Common Stock issuable upon conversion of the senior secured convertible notes, with a current conversion price of $36.40 per share; |

| • |     | 1,642,871 shares of Common Stock issuable upon the exercise of the warrants to purchase shares of Common Stock, with an exercise price of $22.72 per share; |

| • |     | 131,472 shares of Common Stock issuable upon the exercise of the warrants to purchase shares of Common Stock, with an exercise price of $25.81 per share; and |

| • |     | 3,250,000 shares of Common Stock, issuable upon the exercise of the warrants to purchase shares of Common Stock, with an exercise price of $1.20 per share. |

22

RISK FACTORS Investing in our securities involves a high degree of risk. Before making an investment decision, you should consider carefully the following risk factors, as well as the other information set forth in this prospectus, including matters addressed in the section of this prospectus titled “Cautionary Note Regarding Forward-Looking Statements”. If any of these risks actually occur, it may materially harm our business, financial condition, liquidity and results of operations. As a result, the market price of our