Company: TEM
Filing Date: 2025-08-08
Form Type: S-3ASR
Source: 0001193125-25-175993
Chunk: 73

Company: Tempus AI, Inc.
Filing Date: 2025-08-08
Form: S-3ASR
Chunk 73
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 Class A common stock to decline, resulting in a loss of all or part of your investment. Please also carefully read the section titled “Special Note Regarding Forward-Looking Statements.”

Risks Related to This Offering

Future sales of our Class A common stock in the public market could cause the market price of our Class A common stock to decline.

Sales of a substantial number of shares of our Class A common stock in the public market, or the perception that these sales might occur,
could depress the market price of our Class A common stock and could impair our ability to raise capital through the sale of additional equity securities. Many of our existing equity holders have substantial unrecognized gains on the value of
the equity they hold based upon the price of our initial public offering (“IPO”), and therefore they may take steps to sell their shares or otherwise secure the unrecognized gains on those shares. All of the Class A common stock sold
in our IPO is freely tradable without restrictions or further registration under the Securities Act, except for any shares held by our affiliates as defined in Rule 144 under the Securities Act (“Rule 144”). We are unable to predict the
timing of or the effect that such sales may have on the prevailing market price of our Class A common stock.

Sales, short sales, or
hedging transactions involving our equity securities, whether or not we believe them to be prohibited, could adversely affect the price of our Class A common stock.

In addition, we have filed a universal shelf registration statement (which allows us to offer and sell securities from time to time pursuant
to one or more offerings at prices and terms to be determined at the time of sale), as well as registration statements registering all shares of Class A common stock that we has been issued under our 2015 EIP or has or may be issued under our
2024 EIP and 2024 ESPP. All of the Class A common stock sold pursuant to such plans is freely tradable without restrictions or further registration under the Securities Act, except for any shares held by our affiliates as defined in Rule 144.

We will have broad discretion in the use of the net proceeds from this offering and may not use them effectively.

We will have broad discretion in the application of the net proceeds from this offering, including for any of the purposes described in the
section titled “Use of Proceeds,” and you will not have the opportunity as part of your investment decision to assess whether the net proceeds are being used appropriately. Because of the number and variability of factors that will
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