Company: PACB
Filing Date: 2025-04-23
Form Type: DEF 14A
Source: 0001299130-25-000090
Chunk: 2

Company: PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
Filing Date: 2025-04-23
Form: DEF 14A
Chunk 2
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vote.com. All you have to do is enter the control number located on your proxy card.

TABLE OF CONTENTS

YOUR VOTE IS IMPORTANT. Whether or not you plan to attend the Annual Meeting, please submit your vote via the internet, telephone or mail as soon as possible.

By Order of the Board of Directors,

Brett Atkins, J.D., Ph.D.

General Counsel and Corporate Secretary

Menlo Park, California

April 23, 2025

TABLE OF CONTENTS

<div align='center'>TABLE OF CONTENTS</div>

|                                                                                               |     | Page |
| GENERAL INFORMATION                                                                           |     |    1 |
| QUESTIONS AND ANSWERS ABOUT THE ANNUAL MEETING AND THESE PROXY MATERIALS                      |     |    1 |
| CORPORATE GOVERNANCE                                                                          |     |    7 |
| Overview                                                                                      |     |    8 |
| Board Leadership Structure                                                                    |     |    8 |
| The Board’s Role in Risk Oversight                                                            |     |   10 |
| Director Independence                                                                         |     |   10 |
| Director Nominations                                                                          |     |   10 |
| Delinquent Section 16(a) Reports                                                              |     |   11 |
| Code of Business Conduct                                                                      |     |   11 |
| Communication with the Board of Directors                                                     |     |   12 |
| BOARD OF DIRECTORS AND COMMITTEES OF THE BOARD                                                |     |   13 |
| Board and Committee Meetings                                                                  |     |   13 |
| Board Committees                                                                              |     |   18 |
| Director Compensation                                                                         |     |   21 |
| PROPOSAL 1 — ELECTION OF DIRECTORS                                                            |     |   25 |
| PROPOSAL 2 — RATIFICATION OF THE APPOINTMENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM |     |   27 |
| PROPOSAL 3 — ADVISORY VOTE ON APPROVAL OF EXECUTIVE COMPENSATION                              |     |   29 |
| PROPOSAL 4 — APPROVAL OF AMENDMENT TO THE 2020 EQUITY INCENTIVE PLAN                          |     |   30 |
| CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS                                          |     |   45 |
| SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT                                |     |   46 |
| EXECUTIVE OFFICERS                                                                            |     |   49 |
| EXEC