Company: TVRD
Filing Date: 2025-01-27
Form Type: S-4/A
Source: 0001104659-25-006050
Chunk: 674

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-01-27
Form: S-4/A
Chunk 674
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alkon TT Holdings, LLC. The address for Palkon entities is 1688 Meridian Ave, Suite 700, Miami Beach, FL 33139. Dr. Wirk may be deemed to share the power to direct the disposition and vote of the shares held by Palkon Holdings, LLC, but disclaims beneficial ownership of all shares held by Palkon Holdings, LLC except to any pecuniary interest therein. |

| (11) | Consists of stock options exercisable within 60 days of January 15, 2025. |

| (12) | Consists of (i) 1,931,574 shares of combined company common stock beneficially held by Tvardi’s current directors and executive officers as a group, and (ii) 1,640,968 shares common stock issuable upon the exercise of stock options held by Tvardi’s current directors and executive officers that are exercisable within 60 days of January 15, 2025. |

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<div align='center'>LEGAL MATTERS</div>

Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. will pass upon the validity of the Cara common stock offered by this proxy statement/prospectus.

<div align='center'>EXPERTS</div>

Cara

The financial statements of Cara Therapeutics, Inc. as of December 31, 2023 and 2022 and for the years then ended and included in this proxy statement/prospectus have been audited by audited by Ernst & Young LLP, independent registered public accounting firm, as set forth in their report thereon. Such financial statements are included in reliance upon such report given on the authority of such firm as experts in accounting and auditing.

Tvardi

The financial statements of Tvardi Therapeutics, Inc. as of December 31, 2023 and 2022 and for each of the two years in the period ended December 31, 2023, included in this proxy statement/prospectus have been audited by Deloitte & Touche LLP, independent registered public accounting firm, as stated in their report. Such financial statements are included in reliance upon the report of such firm given their authority as experts in accounting and auditing.

<div align='center'>WHERE YOU CAN FIND MORE INFORMATION</div>

Cara has filed with the SEC the Registration Statement, of which this proxy statement/prospectus forms a part. The Registration Statement registers the shares of Cara