Company: PSTV
Filing Date: 2025-08-04
Form Type: DRS
Source: 0000950123-25-006916
Chunk: 2

Company: PLUS THERAPEUTICS, INC.
Filing Date: 2025-08-04
Form: DRS
Chunk 2
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 stockholder.

The shares of common stock to which
this prospectus relates may be issued by us to Lincoln Park, subject to certain limitations described in this prospectus, pursuant to a purchase agreement, dated as of June 17, 2025 we entered into with Lincoln Park (the “Purchase
Agreement”). As of the date of this prospectus, we have received gross proceeds of approximately $[2.8] million from sales of shares of common stock pursuant to the Purchase Agreement, the resale of which shares were registered pursuant to a
separate registration statement on Form S-1 initially filed on June 18, 2025 (as amended, the “Prior Registration Statement”). We are not selling any securities under this prospectus and will
not receive any of the proceeds from the sale of our common stock by the selling stockholder. However, we may receive up to $25 million aggregate gross proceeds (the “Initial Available Amount”) from sales of common stock to Lincoln
Park under the Purchase Agreement and, upon our receipt of gross proceeds equal to the full Initial Available Amount from such sales, the total aggregate dollar amount that will be available to us under the Purchase Agreement will automatically
increase by an additional $25 million aggregate gross proceeds (such additional amount, the “Additional Available Amount”), and thereafter we may receive up to such Additional Available Amount (or up to a total of $50 million
aggregate gross proceeds (the “Total Available Amount”)) from sales of common stock to Lincoln Park under the Purchase Agreement. Pursuant to the Purchase Agreement, as consideration for its irrevocable commitment to purchase up to the
Initial Available Amount of shares of our common stock at our direction under the Purchase Agreement, we agreed to pay Lincoln Park a commitment fee of $500,000 (the “Initial Commitment Fee”), on or prior to August 8, 2025 (the
“Initial Commitment Fee Trigger Date”) in cash or, if we comply with certain requirements set forth in the Purchase Agreement, by issuing shares of our common stock with a per share value calculated in accordance with the Purchase
Agreement (such shares, the “Initial Commitment Shares”), or any combination thereof. We [intend to issue] [1,612,903] shares of our common stock with a per share value of $[0.31] on August 8, 2025 as the Initial Commitment Shares.

We also agreed that, upon our receipt of aggregate gross proceeds equal to the Initial Available Amount (the