Company: PFSA
Filing Date: 2025-05-09
Form Type: S-4/A
Source: 0001213900-25-041151
Chunk: 299

Company: Profusa, Inc.
Filing Date: 2025-05-09
Form: S-4/A
Chunk 299
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, and timing of reimbursement. 4,5Additional consideration was also given to the number of accounts required for the conversion of user needed to achieve these penetration levels. 6 •Regarding the Lumee Oxygen product, as direct tissue perfusion measurement technologies are currently limited on the market, Profusa’s revenue assumption is more directly based on pricing and the likelihood of adoption by physicians and providers to absorb the costs within the current DRG codes for reimbursement. 7Through internal and market research it was determined that the price point of 600 Euros for Critical Limb Ischemia (CLI) patients and 300 Euros for Peripheral Arterial Disease (PAD) patients per year provide the proper incentive for adoption. 8Associated growth in penetration and revenue is assumed after reimbursement is achieved 3 -5years, depending on segments, post launch. 9 ____________ 1https://ec.europa.eu/urostat/web/population -demography/population -housing-censuses/database — only population 18 and over was considered 2https://www.cdc.gov/diabetes/basics/prediabetes.html#:~:text=What%20Is%20Prediabetes%3F,t%20know%20they%20have%20it. 3https://diabetesatlas.org/data/en/region/3/eur.html 4https://www.mddionline.com/diabetes/look -competitive-landscape-diabetes-devices 5https://www.businesswire.com/news/home/20170519005456/en/According -to-THE-SAGE-GROUP-Peripheral-Artery-Disease- PAD -Afflicts-28-Million-Western-Europeans-and-4.2 -Million-Suffer-From-Critical-Limb-Ischemia-CLI— Numbers exclude UK which no longer honors CE mark 6https://www.businesswire.com/news/home/20170519005456/en/According -to-THE-SAGE-GROUP-Peripheral-Artery-Disease- PAD -Afflicts-28-Million-Western-Europeans-and-4.2 -Million-Suffer-From-Critical-Limb-Ischemia-CLI— Numbers exclude UK which no longer honors CE mark 7https://onlinelibrary.wiley.com/doi/abs/10.1002/hpm.2669 8Medtech 360 Report. Peripheral Vascular Devices Market Analysis US 2019 9Medtech 360 Report. Peripheral Vascular Devices