Company: ARVN
Filing Date: 2025-02-11
Form Type: S-8
Source: 0001655759-25-000017
Chunk: 2

Company: ARVINAS, INC.
Filing Date: 2025-02-11
Form: S-8
Chunk 2
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 on Form S-1/A (File No. 333-227112) and incorporated herein by reference. |
| (4) |     | Previously filed with the Securities and Exchange Commission on September 14, 2018 as Exhibit 10.6 to the Registrant’s Registration Statement on Form S-1/A (File No. 333-227112) and incorporated herein by reference. |
| *   |     | Filed herewith                                                                                                                                                                                                          |

### SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of New Haven, State of Connecticut, on this 11th day of February, 2025.

| ARVINAS, INC. |     |                                       |
| By:           |     | /s/ John Houston, Ph.D.               |
|               |     | John Houston, Ph.D.                   |
|               |     | President and Chief Executive Officer |

### POWER OF ATTORNEY AND SIGNATURES
We, the undersigned officers and directors of Arvinas, Inc., hereby severally constitute and appoint John Houston, Ph.D. and Andrew Saik, and each of them singly, our true and lawful attorneys with full power to any of them, and to each of them singly, to sign for us and in our names in the capacities indicated below the Registration Statement on Form S-8 filed herewith and any and all amendments to said Registration Statement, and generally to do all such things in our names and on our behalf in our capacities as officers and directors to enable Arvinas, Inc. to comply with the provisions of the Securities Act of 1933, as amended, and all requirements of the Securities and Exchange Commission, hereby ratifying and confirming our signatures as they may be signed by our said attorneys, or any of them, to said registration statement and any and all amendments thereto.

Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.

| Signature                       
 /s/ John Houston, Ph.D.         |     | Title                                                                     
 President, Chief Executive Officer and Chairman of the Board of Directors 
 (principal executive officer)