Company: HURA
Filing Date: 2025-05-08
Form Type: S-4/A
Source: 0001193125-25-116090
Chunk: 4

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-05-08
Form: S-4/A
Chunk 4
---
expressed in the Securities Act and is therefore unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such a director, officer or controlling person in connection with the securities being registered, we will, unless in the opinion of our counsel the
matter has been settled by controlling precedent,

II-1

submit to a court of appropriate jurisdiction the question whether such indemnification by us is against public policy as expressed hereby in the Securities Act and we will be governed by the final adjudication of such issue. TuHURA has entered agreements to indemnify TuHURA’s directors and officers to the maximum extent allowed under Nevada law. These agreements, among other things, indemnify our directors and officers for certain expenses (including attorneys’ fees), judgments, fines and settlement amounts reasonably incurred by such person in any action or proceeding, including any action by or in TuHURA’s right, on account of any services undertaken by such person on behalf of TuHURA or that person’s status as a member of TuHURA’s board of directors. See also the undertakings set out in response to Item 22 of this Registration Statement. Item 21. Exhibits and Financial Statement Schedules Exhibit Index

| Exhibit 
 Number  
 2.1††   
 2.2***  |     | Description                                                                                                                                                                                                                                                              
 Agreement and Plan of Merger, dated as of December 11, 2024, by and among TuHURA Biosciences, Inc., Kineta, Inc., Hura Merger Sub I, Inc., Hura                                                                                                                          
 Merger Sub II, LLC and Craig Philips (incorporated by reference to Exhibit 2.1 of TuHURA’s Current Report on Form 8-K filed with the SEC on December 12, 2024)                                                                                                           
 First Amendment to the Agreement and Plan of Merger, dated May 5, 2025, by and among TuHURA Biosciences, Inc., Kineta, Inc., Hura Merger Sub I,                                                                                                                          
 Inc., Hura Merger Sub II, LLC and Craig Philips.                                                                                                                                                                                                                         |
|:--------|:----|:-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 2.3††   |     | Agreement and Plan of Merger, dated as