Company: PRTA
Filing Date: 2025-09-25
Form Type: PRE 14A
Source: 0001140361-25-036135
Chunk: 4

Company: PROTHENA CORP PUBLIC LTD CO
Filing Date: 2025-09-25
Form: PRE 14A
Chunk 4
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 in this Proxy Statement, and any references to our website herein are intended for textual references only.

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TABLE OF CONTENTS

THE PROXY PROCESS AND SHAREHOLDER VOTING QUESTIONS AND ANSWERS ABOUT THESE PROXY MATERIALS AND VOTING

| 1. |     | Who can vote at the EGM? |

Only shareholders of record at the close of business on the Record Date will be entitled to vote at the EGM. As of the Record Date, there were 53,829,928 ordinary shares issued and outstanding and entitled to vote. Shareholder of Record: Shares Registered in Your Name If, on the Record Date, your shares were registered directly in your name with the transfer agent for our ordinary shares, Computershare Trust Company, N.A., then you are a shareholder of record. As a shareholder of record, you may vote in person at the EGM or vote by proxy. Whether or not you plan to attend the EGM, we urge you to fill out and return the enclosed proxy card or vote by proxy over the telephone or on the internet as instructed below to ensure your vote is counted. Beneficial Owner: Shares Registered in the Name of a Broker, Bank, or Other Agent If, on the Record Date, your shares were not held in your name, but rather in an account at a brokerage firm, bank, dealer, or other similar organization, who in turn hold through The Depository Trust Company (“DTC”), then you are the beneficial owner of shares held in “street name” and these proxy materials are being forwarded to you by that organization. The organization holding your account is considered the shareholder of record for purposes of voting at the EGM. As a beneficial owner, you have the right to direct your broker or other agent on how to vote the shares in your account. You are also invited to attend the EGM. However, since you are not the shareholder of record, you may not vote your shares in person at the EGM unless you request and obtain a valid proxy card from your broker or other agent who is the record holder of the shares, authorizing you to vote at the EGM.

| 2. |     | What am I being asked to vote on? |

You are being asked to vote FOR the approval of a reduction of the Company’s capital to facilitate the creation of distributable reserves. In addition, you are entitled to vote on any other matters that are properly brought before the EGM. We are not aware of any other matter that