Company: PFSA
Filing Date: 2025-08-29
Form Type: S-1
Source: 0001213900-25-082672
Chunk: 39

Company: Profusa, Inc.
Filing Date: 2025-08-29
Form: S-1
Chunk 39
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 our business and we cannot anticipate all of the ways in which the current economic climate and financial market conditions could adversely impact our business. We may experience pricing pressures from contract suppliers or manufacturers on which we rely. We expect that there will be supply constraints and our suppliers may continue to raise prices, which we may not be able to offset through manufacturing efficiencies or pricing actions. Pricing pressures from third parties could increase our costs and force us to increase the prices of our products if we are unable to enter into alternative arrangements with other suppliers or manufacturers, potentially leading to decreased customer demand. Manufacturing difficulties and/or any disruption at our facilities may adversely affect our manufacturing operations and related product sales, and increase our expenses. Our products are manufactured at two facilities located in California, with limited alternate facilities. If an event occurs at one of our facilities that results in damage to, or closure of, one or more of such facilities, or if our distributions from those facilities are limited or restricted in any way, we may be unable to manufacture the relevant products at the previous levels or at all. Because of the time required to approve and lease a manufacturing facility, an alternate facility and/or a third -partymay not be available on a timely basis to replace production capacity in the event manufacturing capacity is lost. We take precautions to safeguard our facilities, which include manufacturing protocols, insurance, health and safety protocols, and off -sitestorage of data. However, a natural or man -madedisaster, such as fire, flood, earthquake, act of terrorism, cyber -attackor other disruptive event, such as the COVID -19pandemic or another public health emergency, could cause substantial delays in our operations, damage, destroy or limit our manufacturing equipment, inventory, or records and cause us to incur additional expenses. Earthquakes and fires are of particular significance since our manufacturing facilities in California are located in an earthquake -pronearea. In the event our existing manufacturing facilities or equipment are affected by man -madeor natural disasters, we may be unable to manufacture products for sale or meet customer demands or sales projections. If our manufacturing operations were curtailed or ceased, it would seriously harm our business. The insurance we maintain against fires, floods, earthquakes and other natural disasters and similar events may not be adequate to cover our losses in any particular case. Further, insurance coverage may not be available or successfully secured for loss profits or business interruption relating to the COVID -19pandemic and its impacts. 23 Customer or third-party complaints or negative reviews or publicity