Company: HCWB
Filing Date: 2025-02-21
Form Type: DEF 14A
Source: 0001193125-25-032115
Chunk: 80

Company: HCW Biologics Inc.
Filing Date: 2025-02-21
Form: DEF 14A
Chunk 80
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 | Certify that, as of the date hereof, the conditions set forth in Section 7.1 of the Agreement are 
 satisfied.                                                                                        |

HCW BIOLOGICS INC.

| By: |     |        |
|     |     | Name:  |
|     |     | Title: |

EXHIBIT B FORM OF OFFICER’S CERTIFICATE OF HCW BIOLOGICS INC. Pursuant to Section 7.1(j)of that certain equity purchase agreement, dated February 20, 2025 (the “ Agreement”), by and between HCW Biologics Inc. (the “ Company”) and Square Gate Capital Master Fund, LLC – Series 4 (the “ Investor”), the undersigned, in his capacity as Chief Financial Officer of the Company, and not in his individual capacity, hereby certifies, as of the date hereof (such date, the “ Condition Satisfaction Date”), the following: 1. The representations and warranties of the Company contained in the Agreement are true and correct in all material respects as of the Condition Satisfaction Date as though made on the Condition Satisfaction Date (except for representations and warranties specifically made as of a particular date) with respect to all periods, and as to all events and circumstances occurring or existing to and including the Condition Satisfaction Date, except for any conditions which have temporarily caused any representations or warranties of the Company set forth in the Agreement to be incorrect and which have been corrected with no continuing impairment to the Company or the Investor; and 2. All of the conditions precedent to the obligation of the Investor to purchase Put Shares set forth in the Agreement, including but not limited to Section 7.1of the Agreement, have been satisfied as of the Condition Satisfaction Date. Capitalized terms used herein shall have the meanings set forth in the Agreement unless otherwise defined herein. IN WITNESS WHEREOF, the undersigned has hereunto affixed his hand as.

| By: |     |        |
|     |     | Name:  |
|     |     | Title: |

EXHIBIT C

FORM OF TRANSFER AGENT INSTRUCTION LETTER

EXHIBIT D

FORM OF REGISTRATION RIGHTS AGREEMENT

REGISTRATION RIGHTS AGREEMENT

REGISTRATION RIGHTS AGREEMENT (this “”), dated as of February 20, 2025 (the “”),
is entered into by and between HCW Biologics Inc., a corporation incorporated in the State of Delaware (the “”), and Square Gate Capital Master Fund, LLC - Series