Company: HURA
Filing Date: 2025-05-23
Form Type: 424B3
Source: 0001193125-25-125499
Chunk: 357

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-05-23
Form: 424B3
Chunk 357
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 |     | the Kineta stockholders may not approve the Merger Agreement Proposal; |

| • |     | the substantial costs to be incurred in connection with the Mergers, including those incurred regardless of 
 whether the Mergers are consummated;                                                                        |

| • |     | that there are limited circumstances in which the TuHURA Board of Directors may terminate the Merger Agreement; |

| • |     | that TuHURA would be required to pay to Kineta a termination fee of $1,000,000 in the event the Merger Agreement                                                            
 were to be terminated because of TuHURA’s failure to close the Concurrent Investment and obtain gross proceeds not less than $20,000,000 therefrom before the outside date; |

| • |     | the potential impact on the market price of TuHURA Common Stock as a result of the issuance of the Merger 
 Consideration to Kineta stockholders;                                                                     |

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| • |     | That certain executive officers and directors of TuHURA may have interests in the Mergers that may be different 
 from, or in addition to, the interests of TuHURA stockholders generally; and                                    |

| • |     | risks of the type and nature described under entitled “Risk Factors” and “Cautionary Statement 
 Regarding Forward-Looking Statements.”                                                         |

The foregoing description of TuHURA’s consideration of the factors supporting the Mergers is forward-looking in nature. This information should be read in light of the factors discussed under “Cautionary Statement Regarding Forward-Looking Statements.” Recommendation of the Kineta Board of Directors; Kineta’s Reasons for the Transactions On December 11, 2024, the Kineta Board of Directors unanimously:

| • |     | determined that the Merger Agreement and the Mergers are fair to, and in the best interests of, Kineta and its 
 stockholders;                                                                                                  |

| • |     | approved and declared advisable the Merger Agreement and the Mergers; |

| • |     | directed the Merger Agreement be submitted for adoption at a meeting of Kineta stockholders; and |

| • |     | recommended that Kineta stockholders vote in favor of the adoption of the Merger Agreement; |

ACCORDINGLY, THE KINETA BOARD OF DIRECTORS HAS APPROVED THE MERGER AGREEMENT AND UNANIMOUSLY RECOMMENDS THAT KINETA STOCKHOLDERS VOTE “FOR” THE MERGER