Company: TAK
Filing Date: 2025-06-26
Form Type: 424B5
Source: 0001395064-25-000101
Chunk: 80

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-06-26
Form: 424B5
Chunk 80
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 may be passed upon for us by Sullivan & Cromwell LLP as to matters of United States federal law and New York State law and by Nishimura & Asahi (Gaikokuho Kyodo Jigyo) as to matters of Japanese law, and for any underwriters or agents by Simpson Thacher & Bartlett LLP or other counsel named in the applicable prospectus supplement.

### EXPERTS
The consolidated financial statements of Takeda Pharmaceutical Company Limited and its subsidiaries as of March 31, 2025 and 2024 and for each of the years in the three-year period ended March 31, 2025, and management’s assessment of the effectiveness of internal control over financial reporting as of March 31, 2025, have been incorporated by reference herein and in the registration statement in reliance upon the reports of KPMG AZSA LLC, an independent registered public accounting firm, incorporated by reference herein, and upon the authority of said firm as experts in accounting and auditing. KPMG AZSA LLC’s address is AZSA Center Building, 1-2, Tsukudo-cho, Shinjuku-ku, Tokyo 162-8551, Japan.

### ENFORCEMENT OF CIVIL LIABILITIES
TPC is a joint stock corporation incorporated under the laws of Japan. Many of its directors and executive officers are residents of countries other than the United States. Although some of TPC’s affiliates have substantial assets in the United States, substantially all of the assets of TPC are located outside the United States. As a result, it may not be possible for investors to effect service of process within the United States or elsewhere outside Japan upon TPC or its directors and executive officers or to enforce against it or such persons judgments obtained in the United States courts or elsewhere, whether or not predicated upon the civil liability provisions of the United States securities laws or other laws of the United States or any state thereof. Nishimura & Asahi (Gaikokuho Kyodo Jigyo), our Japanese counsel, has advised us that, in original actions or in actions for enforcement of judgments of U.S. federal or state courts brought before Japanese courts, there is in general doubt as to the enforceability of liabilities based solely on U.S. federal and state securities laws.

TPC’s agent for service of process is Takeda Pharmaceuticals U.S.A., Inc. (or any successor thereto).

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#### TPC’s REGISTERED HEAD