Company: CNTB
Filing Date: 2025-06-10
Form Type: S-8
Source: 0001193125-25-138485
Chunk: 1

Company: Connect Biopharma Holdings Ltd
Filing Date: 2025-06-10
Form: S-8
Chunk 1
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 pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

EXPLANATORY NOTE This Registration Statement registers the offer and sale of (i) an additional 7,000,000 ordinary shares, par value $0.000174 per share (“Ordinary Shares”), of Connect Biopharma Holdings Limited (the “Registrant”) that are issuable under the Connect Biopharma Holdings Limited 2021 Stock Incentive Plan (the “2021 Plan”) pursuant to the provisions of the 2021 Plan providing for an automatic increase in the number of Ordinary Shares issuable thereunder, and (ii) 4,500,000 Ordinary Shares that are issuable under the Connect Biopharma Holdings Limited 2024 Employment Inducement Incentive Award Plan (the “Inducement Plan” and, together with the 2021 Plan, the “Plans”). The securities to be registered hereby may be represented by American Depositary Shares (“ADSs”) of the Registrant. Each ADS represents one Ordinary Share. The Registrant’s ADSs issuable upon deposit of the securities registered hereby have been registered under a separate registration statement on Form F-6(File No. 333-254215).In accordance with General Instruction E to Form S-8,the contents of the prior registration statements on Form S-8,(i) File No. 333-266006,filed with the Securities and Exchange Commission (the “Commission”) on July 1, 2022, and (ii) File No. 333-254524,filed with the Commission on March 19, 2021, in each case previously filed with respect to the 2021 Plan, are hereby incorporated by reference herein. PART I INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS Item 1. Plan Information.* Item 2. Registrant Information and Employee Plan Annual Information.* * Information required by Part I of Form S-8to be contained in the Section 10(a) prospectus is omitted from this Registration Statement in accordance with Rule 428 under the Securities Act of 1933 (the “Securities Act”) and the introductory note to Part I of Form S-8.The documents containing information specified in this Part I of Form S-8will be separately provided to the participants covered by the Plans, as specified by Rule 428(b)(1) under the Securities Act. PART II INFORMATION REQUIRED IN THE REGISTRATION STATEMENT Item 3. Incorporation of Documents by Reference