Company: RNLXY
Filing Date: 2025-09-04
Form Type: F-6 POS
Source: 0001193805-25-001256
Chunk: 0

Company: Renalytix plc
Filing Date: 2025-09-04
Form: F-6 POS
Chunk 0
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<div align='center'>SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

__________________________________

POST-EFFECTIVE AMENDMENT NO. 1 TO FORM F-6

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933 FOR AMERICAN DEPOSITARY
SHARES EVIDENCED BY

AMERICAN DEPOSITARY RECEIPTS

_____________

Renalytixplc

(Exact name of issuer of deposited securities as
specified in its charter)

_____________

N/A

(Translation of issuer’s name into English)

_____________

England and Wales

(Jurisdiction of incorporation or organization
of issuer)

__________________________________

CITIBANK, N.A.

(Exact name of depositary as specified in its charter)

_____________

388 Greenwich Street

New York, New York 10013

(877) 248-4237

(Address, including zip code, and telephone number,
including area code, of depositary’s principal executive offices)

_____________

Renalytix AI, Inc.

421 Wakara Way, Suite 309

Salt Lake City, UT 84108

(646) 397-3970

(Address, including zip code, and telephone number,
including area code, of agent for service)

__________________________________

Copies to:</div>

| Mark E. Rosenstein, Esq.               
 Stevens & Lee PC                       
 620 Freedom Business Center, Suite 200 
 King of Prussia, PA 19406              
 (610) 205-6050                         | Jean-Claude Lanza, Esq.            
 Herman H. Raspé, Esq.              
 Patterson Belknap Webb & Tyler LLP 
 1133 Avenue of the Americas        
 New York, New York 10036           
 (212) 336-2301                     |

<div align='center'>__________________________________</div>

| It is proposed that this filing become effective under Rule 466:                                    | ☐                        
 immediately upon filing. |
|                                                                                                     | ☐  on (Date) at (Time).  |
| If a separate                                                                                       
 registration statement has been filed to register the deposited shares, check the following box:  ☐ |                          |

<div align='center'>__________________________________

CALCULATION OF REGISTRATION FEE</div>

| Title of Each Class of                                                                                                                   
 Securities to be Registered                                                                                                              | Amount to be 
 Registered   | Proposed Maximum          
 Aggregate Price Per Unit* | Proposed Maximum           
 Aggregate Offering Price** | Amount of        
 Registration