Company: TEM
Filing Date: 2025-08-08
Form Type: S-3ASR
Source: 0001193125-25-175993
Chunk: 63

Company: Tempus AI, Inc.
Filing Date: 2025-08-08
Form: S-3ASR
Chunk 63
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 of a registration statement on Form S-3 that we filed with the Securities and
Exchange Commission (the “SEC”) utilizing a “shelf” registration process as a “well-known seasoned issuer” as defined in Rule 405 under the Securities Act.

In accordance with the terms of the sales agreement, we may offer and sell shares of our Class A common stock from time to time through
or to Morgan Stanley, Cantor, TD Securities and/or Allen, acting as sales agent or principal, having an aggregate offering price of up to $500 million. We may also authorize one or more prospectus supplements or free writing prospectuses to be
provided to you that may contain material information relating to this offering. Any prospectus supplement and any related free writing prospectus that we may authorize to be provided to you may also add, update or change any of the information
contained in this prospectus or in the documents that we have incorporated by reference into this prospectus. We urge you to read carefully this prospectus, any applicable prospectus supplement and any free writing prospectuses we have authorized
for use in connection with this offering, together with the information incorporated herein by reference as described in the section titled “Incorporation of Certain Information by Reference,” before buying any of the securities being
offered.

We have not, and the sales agents have not, authorized anyone to provide you with any information or to make any representations
other than those contained in this prospectus, any applicable prospectus supplement or any free writing prospectuses prepared by or on behalf of us or to which we have referred you. We and the sales agents take no responsibility for, and can provide
no assurance as to the reliability of, any other information that others may give you. This prospectus is an offer to sell and a solicitation for offers to purchase only the securities offered hereby, but only under circumstances and in
jurisdictions where it is lawful to do so.

The information appearing in this prospectus, any applicable prospectus supplement and any
related free writing prospectus is accurate only as of the date on the front of the document and any information we have incorporated by reference is accurate only as of the date of the document incorporated by reference, regardless of the time of
delivery of this prospectus, the applicable prospectus supplement or any related free writing prospectus, or any sale of a security. Our business, financial condition, results of operations and prospects may have changed since those dates.

This prospectus contains and incorporates by reference industry, market and