Company: TVRD
Filing Date: 2025-01-27
Form Type: S-4/A
Source: 0001104659-25-006050
Chunk: 571

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-01-27
Form: S-4/A
Chunk 571
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 on various other assumptions that Cara believes to be reasonable under the circumstances at the time such estimates are made. Actual results and outcomes may differ materially from Cara’s estimates, judgments, and assumptions. Cara periodically reviews its estimates in light of changes in circumstances, facts, and experience. The effects of material revisions in estimates are reflected in the financial statements prospectively from the date of the change in estimate. Note 2 of Cara’s Notes to Consolidated Financial Statements as of December 31, 2023,Summary of Significant Accounting Policies, within this proxy statement/prospectus describes the significant accounting policies and methods used in the preparation of Cara’s condensed consolidated financial statements.

Cara defines its critical accounting estimates as those subjective estimates and judgments about matters that are uncertain and are likely to have a material impact on Cara’s financial condition and results of operations as well as the specific manner in which Cara applies U.S. GAAP. Cara’s critical accounting policies that require significant judgments and estimates are more fully described in Note 2 to Cara’s audited financial statements as of December 31, 2023 contained within this proxy statement/prospectus. There have been no significant changes to Cara’s critical accounting policies that require significant judgments and estimates from those disclosed in its contained elsewhere in this proxy statement/prospectus.

Accounting Pronouncements Recently Adopted; Recent Accounting Pronouncements Not Yet Adopted

Cara does not expect that any recently issued accounting pronouncements will have a material effect on its condensed consolidated financial statements. Refer to Note 2 of Cara’s Notes to Condensed Consolidated Financial Statements as of September 30, 2024 within this proxy statement/prospectus, as well as Note 2 of Cara’s Notes to Consolidated Financial Statements as of December 31, 2023, Summary of Significant Accounting Policieswithin this proxy statement/prospectus for a full description of accounting pronouncements recently adopted, and issued but not yet adopted, if applicable.

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TVARDI MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS You should read the following discussion of Tvardi’s financial condition and results of operations in conjunction with Tvardi’s financial statements and the related notes included elsewhere in this proxy statement/ prospectus. In addition to historical financial information, this discussion contains forward-looking statements based upon current expectations that involve risks and uncertainties. Tvardi’s actual results could differ materially from those anticipated in these forward-looking statements as a result of various factors. Factors that