Company: CF
Filing Date: 2025-11-21
Form Type: 424B2
Source: 0001104659-25-115010
Chunk: 1

Company: CF Industries Holdings, Inc.
Filing Date: 2025-11-21
Form: 424B2
Chunk 1
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. The notes are a new issue of securities with no established trading market. We do not intend to apply for listing of the notes on any securities exchange or for quotation of the notes on any automated dealer quotation system. Investing in the notes involves a high degree of risk. See “Risk Factors” beginning on page S-11of this prospectus supplement and the information set forth in the Parent’s filings under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), that are incorporated herein by reference.

| ​                                        | ​ | ​ | Per note |   |         |   | ​ | ​ | Total |   |             |   | ​ |
|:-----------------------------------------|:--|:--|:---------|:--|:--------|:--|:--|:--|:------|:--|------------:|:--|:--|
| Public offering price(1)                 | ​ | ​ | ​        | ​ | 99.923% | ​ | ​ | ​ | ​     | $ | 999,230,000 | ​ | ​ |
| Underwriting discount                    | ​ | ​ | ​        | ​ | 0.650%  | ​ | ​ | ​ | ​     | $ |   6,500,000 | ​ | ​ |
| Proceeds, before expenses, to the Issuer | ​ | ​ | ​        | ​ | 99.273% | ​ | ​ | ​ | ​     | $ | 992,730,000 | ​ | ​ |

(1) Plus accrued interest from November 26, 2025, if any, if settlement occurs after that date. Neither the Securities and Exchange Commission (the “SEC”) nor any state or other securities commission has approved or disapproved of these securities or determined if this prospectus supplement or the accompanying prospectus is truthful or complete. Any representation to the contrary is a criminal offense. The underwriters expect to deliver the notes in book-entry only form through The Depository Trust Company, Clearstream Banking S.A, and Euroclear Bank, S.A./N.V. as operator of the Euroclear System on or about November 26, 2025. Joint Book-Running Managers

| ​ | Goldman Sachs & Co. LLC | ​ | ​ | BMO Capital Markets | ​ | ​ | Citigroup | ​ |

| ​ | BofA Securities | ​ | ​ | CIBC Capital Markets | ​ | ​ | Scotiabank