Company: TAK
Filing Date: 2025-06-25
Form Type: 20-F
Source: 0001395064-25-000095
Chunk: 131

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-06-25
Form: 20-F
Item: Item 5
Chunk 131
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 profit for the year      33.6                                                     41.8                  
  Non-IFRS:                                                                                                                               
  Adjusted net debt                                        ¥                                         (4,091.3)      ¥          (3,975.5)  
  Adjusted EBITDA                                                                                      1,319.9                   1,441.0  
  Adjusted net debt to adjusted EBITDA ratio               3.1                                                      2.8                   

C. Research and Development, Patents and Licenses, etc.

The information required by this item is set forth in “ Item 4. Information on the Company - B. Business Overview - Research and Development” of this annual report.

D. Trend Information

The information required by this item is set forth in “ Item 5. A. Operating Results - Factors Affecting Our Results of Operations - Periodic Trends” of this annual report.

E. Critical Accounting Estimates

The requirements of this item are not applicable to Takeda, as it prepares its financial statements in accordance with IFRS. Takeda presents information about its critical accounting policies under “ Item 5. A. Operating Results - Critical Accounting Policies” of this annual report.

Table of Contents

Annex to Item 5. Certain Supplemental Non-IFRS Measures as Defined and Presented by Takeda

In addition to its results presented in accordance with IFRS, Takeda presents certain “ Non-IFRS” financial measures on a supplemental basis. These financial measures include Constant Exchange Rate (“ CER”) Change, Core Financial Measures, Net Debt, Adjusted Net Debt, EBITDA, Adjusted EBITDA, Free Cash Flow and Adjusted Free Cash Flow.

Takeda’s management evaluates its results of operations and financial condition and makes operating and investment decisions using both IFRS measures and the non-IFRS measures presented herein. Accordingly, Takeda presents both types of measures to provide investors with additional information to analyze Takeda’s results of operations and financial condition and understand how Takeda’s management assesses the same. Takeda’s non-IFRS measures exclude or adjust the calculation of certain income, cost, cash flow or statement of financial position items which are included in the most closely comparable measures presented in accordance with IFRS. These measures are not prepared in accordance with IFRS and such non-IFRS measures should be considered a supplement to, and not a substitute for, measures prepared in accordance with IFRS