Company: PGEN
Filing Date: 2025-08-19
Form Type: S-3
Source: 0000950103-25-010472
Chunk: 43

Company: PRECIGEN, INC.
Filing Date: 2025-08-19
Form: S-3
Chunk 43
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) | To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent         
 post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth      
 in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar 
 value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum 
 offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the       
 changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the “Calculation  
 of Registration Fee” table in the effective registration statement; and                                                                     |

| (iii) | To include any material information with respect to the plan of distribution not previously disclosed in the registration statement 
 or any material change to such information in the registration statement;                                                           |

provided, however, that
paragraphs (a)(1)(i), (ii), and (iii) do not apply if the information required to be included in a post-effective amendment by those paragraphs
is contained in reports filed with or furnished

<div align='center'>II-2</div>

to the Commission by the registrant pursuant
to section 13 or section 15(d) of the Securities Exchange Act of 1934 (15 U.S.C. 78m or 78o(d)) that are incorporated by reference in
the registration statement, or is contained in a form of prospectus filed pursuant to Rule 424(b) that is part of the registration statement.

| (2) | That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be deemed 
 to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall   
 be deemed to be the initial bona fide offering thereof.                                                                                 |

| (3) | To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the 
 termination of the offering.                                                                                                         |

| (4) | That, for the purpose of determining liability under the Securities Act of 1933 to any purchaser: |

| (A) | Each prospectus filed by the registrant pursuant to Rule 424(b)(3) shall be deemed to be part