Company: INKT
Filing Date: 2025-08-14
Form Type: S-8
Source: 0001193125-25-180815
Chunk: 0

Company: MiNK Therapeutics, Inc.
Filing Date: 2025-08-14
Form: S-8
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As filed with the Securities and Exchange Commission on August 14, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 MiNK Therapeutics, Inc. (Exact name of registrant as specified in its charter)

| Delaware                                 |     |         82-2142067 |
| (State or other jurisdiction of          
 incorporation or organization)           |     |   -I.R.S. Employer 
 Identification No. |
| 149 Fifth Avenue, Suite 500,             
 New York, NY                             |     |              10010 |
| (Address of Principal Executive Offices) |     |          -Zip Code |

MiNK Therapeutics, Inc. 2021 Equity Incentive Plan MiNK Therapeutics, Inc. 2021 Employee Stock Purchase Plan (Full titles of the plans) Jennifer S. Buell, Ph.D. President, Chief Executive Officer and Director MiNK Therapeutics, Inc. 149 Fifth Avenue, Suite 500 New York, NY 10010 (Name and address of agent for service) (212) 994-8250 (Telephone number, including area code, of agent for service) Please send a copy of all communications to: Wesley Holmes, Esq. Latham & Watkins LLP 200 Clarendon Street Boston, MA 02116 (617) 948-6060 Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-acceleratedfiler, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer, “smaller reporting company,” and “emerging growth company” in Rule 12b-2of the Exchange Act.

| Large accelerated filer |     | ☐ |     | Accelerated filer         |     | ☐ |
| Non-accelerated filer   |     | ☒ |     | Smaller reporting company |     | ☒ |
|                         |     |   |     | Emerging growth company   |     | ☒ |

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

Explanatory Note This