Company: SMNR
Filing Date: 2025-08-13
Form Type: 424B3
Source: 0001193125-25-179226
Chunk: 697

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-08-13
Form: 424B3
Chunk 697
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 or calling Semnur Pharmaceuticals, Inc. at 960 San Antonio Road, Palo Alto, CA
94303, Attn: Corporate Secretary.

454

WHERE YOU CAN FIND MORE INFORMATION

Denali has filed this proxy statement/prospectus as part of a registration statement on a Form S-4 with the SEC under
the Securities Act. This proxy statement/prospectus does not contain all of the information included in the registration statement. For further information pertaining to Denali and its securities, you should reference the registration statement and
its exhibits. The descriptions in this proxy statement/prospectus of the provisions of documents filed as exhibits to this proxy statement/prospectus are only summaries of those documents’ material terms. You can read copies of such documents,
along with copies of reports, proxy statements and other information filed by Denali with the SEC at the SEC’s website at http://www.sec.gov. If you would like additional copies of this proxy statement/prospectus or if you have
questions about the Business Combination or the Proposals to be presented at the Meeting, you should contact our proxy solicitor at the following address and telephone number:

P.O. Box 10904

Yakima, WA 98909

Toll-Free: 877 870-8565

Collect: (206) 870-8565

Email:
ksmith@advantageproxy.com

If you are a shareholder of Denali and would like to request documents, please do so by August 26, 2025 in order to
receive them before the Meeting. If you request any documents from us, we will mail them to you by first class mail, or another equally prompt means.

Information and statements contained in this proxy statement/prospectus are qualified in all respects by reference to the copy of the relevant contract or
other document included as an annex to this proxy statement/prospectus.

All information contained in this proxy statement/prospectus relating to Denali
has been supplied by Denali, and all such information relating to Semnur has been supplied by Semnur. Information provided by either Denali or Semnur does not constitute any representation, estimate or projection of any other party.

Neither Denali nor Semnur has authorized anyone to give any information or make any representation about the Business Combination or their respective
companies that is different from, or in addition to, that contained in this proxy statement/prospectus. Therefore, if anyone does give you information of this sort, you should not rely on it