Company: SCLXW
Filing Date: 2025-11-07
Form Type: DEF 14A
Source: 0001193125-25-272322
Chunk: 35

Company: Scilex Holding Co
Filing Date: 2025-11-07
Form: DEF 14A
Chunk 35
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 be “householding” communications to your address, “householding” will continue until you are notified otherwise or until you revoke your consent. If, at any time, you no longer wish to participate in “householding” and would prefer to receive a separate set of proxy materials, please notify your broker, notify our Corporate Secretary at (650) 516-4310or send a written request to: Corporate Secretary at Scilex Holding Company, 960 San Antonio Road, Palo Alto, CA 94303. Stockholders who currently receive multiple copies of proxy materials at their addresses and would like to request “householding” of their communications should contact their brokers. WHERE YOU CAN FIND ADDITIONAL INFORMATION We have filed reports, proxy statements and other information with the SEC. The SEC maintains a website that contains the reports, proxy statements and other information we file electronically with the SEC. The address of the SEC website is http://www.sec.gov. You may request, and we will provide at no cost, a copy of these filings, including any exhibits to such filings, by writing or telephoning us at the following address: Corporate Secretary at Scilex Holding Company, 960 San Antonio Road, Palo Alto, CA 94303. You may also access these filings at our website under the investor relations link at https://www.scilexholding.com/investors/overview. OTHER MATTERS Our Board does not know of any other matters to be presented at the Special Meeting. If any additional matters are properly presented at the Special Meeting, the persons named in the enclosed proxy card will have discretion to vote shares they represent in accordance with their own judgment on such matters. It is important that your shares be represented at the Special Meeting, regardless of the number of shares that you hold. You are, therefore, urged to vote by using the Internet as instructed on the enclosed proxy card or execute and return, at your earliest convenience, the enclosed proxy card in the envelope that has also been provided.

| THE BOARD OF DIRECTORS                          |
| /s/ Henry Ji                                    |
| Henry Ji, Ph.D.                                 |
| Chief Executive Officer, President and Director |
| Palo Alto, CA                                   |
| November 7, 2025                                |

25

SCAN TO VIEW MATERIALS & VOTE wSCILEX HOLDING COMPANY960 SAN ANTONIO RD VOTE BY INTERNET PALO ALTO, CA 94303 Before The Meeting—Go to www.proxyvote.com or scan the QR Barcode aboveUse the Internet to transmit