Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 413

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 413
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 ability of DiamiR Biosciences Corp. to continue as a going concern as described in Note 2 to the financial statements,
and are included in reliance upon such report given on the authority of such firm as experts in accounting and auditing.

The consolidated balance sheet
of DiamiR Biosciences Corp. as of May 31, 2024, and the related consolidated statements of operations, changes in stockholders’
deficit and cash flows for the year ended May 31, 2024, included herein have been audited by Marcum LLP, independent registered public
accounting firm, as set forth in their report appearing elsewhere herein, which contains an explanatory paragraph relating to substantial
doubt about the ability of DiamiR Biosciences Corp. to continue as a going concern as described in Note 2 to the financial statements,
and are included in reliance upon such report given on the authority of such firm as experts in accounting and auditing.

<div align='center'>ENFORCEMENT OF CIVIL LIABILITIES</div>

We are incorporated under
the laws of the Cayman Islands as an exempted company with limited liability. We incorporated in the Cayman Islands because of certain
benefits associated with being a Cayman Islands corporation, such as political and economic stability, an effective judicial system, a
favorable tax system, the absence of foreign exchange control or currency restrictions and the availability of professional and support
services. However, the Cayman Islands have a less developed body of securities laws that provide significantly less protection to investors
as compared to the securities laws of the United States. In addition, Cayman Islands companies may not have standing to sue before the
federal courts of the United States.

All of our assets are located
outside the United States. In addition, some of our directors and officers are residents of jurisdictions other than the United States
and all or a substantial portion of their assets are located outside the United States. As a result, it may be difficult for investors
to effect service of process within the United States upon us or our directors and officers, or to enforce against us or them judgments
obtained in United States courts, including judgments predicated upon the civil liability provisions of the securities laws of the United
States or any state in the United States.

According to our local Cayman
Islands’ counsel, there is uncertainty with regard to Cayman Islands law relating to whether a judgment obtained from the United
States, United Kingdom or Hong Kong courts under civil