Company: PFSA
Filing Date: 2025-10-09
Form Type: S-1
Source: 0001213900-25-097860
Chunk: 417

Company: Profusa, Inc.
Filing Date: 2025-10-09
Form: S-1
Chunk 417
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 the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue. II-6 SIGNATURES Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this prospectus to be signed on its behalf by the undersigned, thereunto duly authorized.

| Date: October 9, 2025 | PROFUSA, INC. 
 By:           | /s/ Ben Hwang                               |
|:----------------------|:--------------|:--------------------------------------------|
|                       | Name:         | Ben Hwang                                   |
|                       | Title:        | Chairman of the Board and Chief Executive   |
|                       |               | -Principal Executive Officer                |
| Date: October 9, 2025 | By:           | /s/ Fred Knechtel                           |
|                       | Name:         | Fred Knechtel                               |
|                       | Title:        | Chief Financial Officer                     |
|                       |               | -Principal Financial and Accounting Officer |

POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENTS, that the undersigned officers and directors of Profusa, Inc., a Delaware corporation, that is filing a registration statement on Form S-1 with the Securities and Exchange Commission under the provisions of the Securities Act of 1933, as amended, hereby constitute and appoint Ben Hwang and Fred Knechtel their true and lawful attorneys-in-fact and agents, with full power of substitution and re-substitution, for him and in his name, place and stead, in any and all capacities, to sign any or all amendments (including post-effective amendments, exhibits thereto and other documents in connection therewith) to the registration statement, any subsequent registration statement filed by the registrant pursuant to Rule 462(b) of the Securities Act of 1933, as amended, which relates to this registration statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all interests and purposes as they might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or either of them, or their substitute or substitutes, may lawfully