Company: DRTSW
Filing Date: 2025-04-28
Form Type: 424B5
Source: 0001213900-25-035799
Chunk: 1

Company: Alpha Tau Medical Ltd.
Filing Date: 2025-04-28
Form: 424B5
Chunk 1
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                                   |   24 |
| ENFORCEABILITY OF CIVIL LIABILITIES       |   25 |
| AUTHORIZED REPRESENTATIVE                 |   25 |
| WHERE YOU CAN FIND MORE INFORMATION;      |   26 |
| INCORPORATION OF INFORMATION BY REFERENCE |   26 |

<div align='center'>S-i

ABOUT THIS PROSPECTUS SUPPLEMENT</div>

This document is in two parts. The first part is
this prospectus supplement, which describes the specific terms of this offering of securities and also adds to and updates information
contained in the accompanying prospectus and the documents incorporated by reference into this prospectus supplement and the accompanying
prospectus. The second part is the accompanying prospectus dated April 13, 2023, included in our registration statement on Form F-3 (File
No. 333-271073), along with the documents incorporated by reference therein, which provides more general information, some of which may
not apply to this offering. Generally, when we refer to this prospectus, we are referring to both parts of this document combined. To
the extent there is a conflict between the information contained in this prospectus supplement, on the one hand, and the information contained
in the accompanying prospectus or in any document incorporated by reference that was filed with the Securities and Exchange Commission
(the “SEC”), before the date of this prospectus supplement, on the other hand, you should rely on the information contained
in this prospectus supplement. If any statement in one of these documents is inconsistent with a statement in another document having
a later date-for example, a document incorporated by reference in the accompanying prospectus-the statement in the document having the
later date modifies or supersedes the earlier statement.

This prospectus supplement and the accompanying
prospectus are part of a “shelf” registration statement that we filed with the SEC. Under this shelf registration process,
we may offer from time to time various securities, of which this offering of securities is a part. Such registration statement also includes
exhibits that provide more detail on the matters discussed in this prospectus supplement and the accompanying prospectus. You should read
this prospectus supplement, the accompanying prospectus, including the information incorporated by reference herein and therein, the exhibits
filed with the SEC and any free writing prospectus that we have authorized for use in connection with this offering in their entirety
before making an investment decision.

We have not authorized anyone to provide you with