Company: APM
Filing Date: 2025-01-03
Form Type: 424B5
Source: 0001213900-25-000606
Chunk: 17

Company: Aptorum Group Ltd
Filing Date: 2025-01-03
Form: 424B5
Chunk 17
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us.

<div align='center'>S-10

PLAN OF DISTRIBUTION</div>

Maxim Group LLC, has agreed to act as the
exclusive Placement Agent in connection with this offering subject to the terms and conditions of the engagement letter, dated
December 31, 2024. The Placement Agent is not purchasing or selling any securities offered by this prospectus supplement, nor is the
Placement Agent required to arrange the purchase or sale of any specific number or dollar amount of our securities but has agreed to
use its best efforts to arrange for the sale of our securities. We have entered into the Securities Purchase Agreement, dated
January 2, 2025, directly with the investors in this offering pursuant to which we agreed to sell to such investors an aggregate of
1,535,000 Class A ordinary shares. We negotiated the price for the Class A ordinary shares offered in this offering with the
investors. The factors considered in determining the price of the Class A ordinary shares included the recent market price of our
Class A ordinary shares, the general condition of the securities market at the time of this offering, the history of, and the
prospects, for the industry in which we compete, our past and present operations, and our prospects for future revenues.

We agreed to indemnify the investors against certain
losses resulting from our breach of any of our representations, warranties, or covenants under agreements with the investors as well as
under certain other circumstances described in the Securities Purchase Agreement.

Fees and Expenses

We have agreed to pay
the Placement Agent a total cash fee equal to seven percent (7.0%) of the aggregate gross proceeds raised in this offering.

The table below reflects the total offering
proceeds, before deducting the estimated offering expenses.

|                                    |     | Per Class A ordinary 
 share                |      |     | Total |           |
|:-----------------------------------|:----|:---------------------|-----:|:----|:------|----------:|
| Public offering price              |     | $                    | 2.00 |     | $     | 3,070,000 |
| Placement Agent fees(1)            |     | $                    | 0.14 |     | $     |   214,900 |
| Proceeds to us, before expenses(2) |     | $                    | 1.86 |     | $     | 2,855,100 |

| (1) | We have agreed to pay the