Company: XOMAP
Filing Date: 2025-10-03
Form Type: 424B5
Source: 0001193125-25-230383
Chunk: 31

Company: XOMA Royalty Corp
Filing Date: 2025-10-03
Form: 424B5
Chunk 31
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certain ongoing outside legal expenses up to $25,000 per calendar quarter for ongoing diligence arising from the transactions contemplated by the Sales Agreement. We estimate that the total expenses of the offering payable by us, excluding
commissions payable to Leerink Partners under the Sales Agreement, will be approximately $0.3 million.

The remaining sales proceeds, after deducting
any expenses payable by us and any transaction fees imposed by any governmental, regulatory, or self-regulatory organization in connection with the sales, will equal our net proceeds for the sale of such Common Stock.

Leerink Partners will provide written confirmation to us following the close of trading on Nasdaq on each day in which Common Stock is sold through it as
sales agent under the Sales Agreement. Each confirmation will include the number of shares of Common Stock sold through it as sales agent on that day and the net proceeds to us.

We will report at least quarterly the number of shares of Common Stock sold through Leerink Partners under the Sales Agreement, the net proceeds to us and the
compensation paid by us to Leerink Partners in connection with the sales of Common Stock.

Settlement for sales of Common Stock will occur on the first
business day that is also a trading day following the date on which any sales were made in return for payment of the net proceeds to us. There is no arrangement for funds to be received in an escrow, trust or similar arrangement.

In connection with the sales of our Common Stock on our behalf, Leerink Partners will be deemed to be an “underwriter” within the meaning of the
Securities Act and the compensation paid to Leerink Partners will be deemed to be underwriting commissions or discounts. We have agreed in the Sales Agreement to provide indemnification and contribution to Leerink Partners against certain
liabilities, including liabilities under the Securities Act. As sales agent, Leerink Partners will not engage in any transactions that stabilize our Common Stock.

S-24

Our Common Stock is listed on Nasdaq and trades under the symbol “XOMA.” The transfer agent of
our Common Stock is currently Equiniti Trust Company, LLC.

Leerink Partners and/or its affiliates may in the future provide various investment banking
and other financial services for us for which services they may in the future receive customary fees.

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LEGAL MATTERS

The validity of the shares of Common Stock offered hereby will be passed upon for us by Gibson, Dunn & Crutcher LLP, San Francisco, California, and,
with respect to matters of