Company: CMA
Filing Date: 2025-08-05
Form Type: 424B5
Source: 0001193125-25-173600
Chunk: 101

Company: COMERICA INC
Filing Date: 2025-08-05
Form: 424B5
Chunk 101
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| • |     | reduce the amount of, or postpone the date fixed for, the payment of any sinking fund payment; |

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| • |     | change the currency or currency unit of payment of any debt security; |

| • |     | reduce the portion of the principal amount of an original issue discount security payable upon acceleration of 
 the maturity thereof;                                                                                          |

| • |     | reduce any amount payable upon redemption of any debt security; |

| • |     | impair the right of a holder to institute suit for the payment of or, if the debt securities provide, any right 
 of repayment at the option of the holder of a debt security;                                                    |

| • |     | reduce the percentage of debt securities of any series, the consent of the holders of which is required for any 
 waiver or modification; or                                                                                      |

| • |     | with respect to the subordinated indenture only, modify the provisions with respect to the subordination of the 
 subordinated debt securities in a manner adverse to the holders.                                                |

Each indenture also permits Comerica and the trustee to amend the indenture in certain circumstances without the consent of the holders of debt securities to evidence Comerica’s merger, the replacement of the trustee, to effect changes that do not affect any outstanding series of debt security, and for certain other purposes. Consolidations, Mergers and Sales of Assets Comerica will not consolidate with or merge into any other person or convey, transfer or lease its properties and assets substantially as an entirety to any person (other than the conveyance, transfer or lease of Comerica’s properties and assets substantially as an entirety to one or more of Comerica’s subsidiaries), and Comerica shall not permit any person to consolidate with or merge into Comerica or convey, transfer or lease its properties and assets substantially as an entirety to Comerica, unless:

| • |     | Comerica is the continuing corporation or the successor corporation is a corporation that expressly assumes the                                                                                                
 payment of the principal of, any interest on, or any other amounts due under the debt securities and the performance and observance of all the covenants and conditions of the indentures binding upon us, and |

| • |     | Comerica or the successor corporation shall not, immediately after the merger or consolidation, sale or 
 conveyance, be in default in the performance of any covenant or condition.                              |

There are no covenants or other provisions in the indentures