Company: TVRD
Filing Date: 2025-10-20
Form Type: S-8
Source: 0001104659-25-100898
Chunk: 4

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-10-20
Form: S-8
Chunk 4
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 (including attorneys’ fees) judgments, fines and amounts paid in settlement actually and reasonably incurred
by the director or officer in connection with any such action, suit or proceeding. Section 145 permits corporations to pay expenses
(including attorneys’ fees) incurred by directors and officers in advance of the final disposition of such action, suit or proceeding.
In addition, Section 145 provides that a corporation has the power to purchase and maintain insurance on behalf of its directors
and officers against any liability asserted against them and incurred by them in their capacity as a director or officer, or arising out
of their status as such, whether or not the corporation would have the power to indemnify the director or officer against such liability
under Section 145.

| ITEM 7. | EXEMPTION FROM REGISTRATION CLAIMED. |

Not applicable.

| ITEM 8. | EXHIBITS. |

| Exhibit 
 Number  |     | Description                                                                                                                                                                                                                                                                                                                     |
| 4.1     |     | Amended and Restated Certificate of Incorporation (incorporated by reference from Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-36279), filed with the SEC on February 7, 2014).                                                                                                                     |
| 4.2     |     | Certificate of Amendment to Amended and Restated Certificate of Incorporation dated June 7, 2024 (First Authorized Shares Amendment) (incorporated by reference from Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-36279), filed with the SEC on June 7, 2024).                                      |
| 4.3     |     | Certificate of Amendment to Amended and Restated Certificate of Incorporation dated December 30, 2024 (First Stock Split Amendment) (incorporated by reference from Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-36279), filed with the SEC on December 30, 2024).                                  |
| 4.4     |     | Certificate of Amendment to the Amended and Restated Certificate of Incorporation of Cara Therapeutics, Inc., dated April 15, 2025 (Second Stock Split Amendment). (incorporated by reference from Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-36279), filed with the