Company: HURA
Filing Date: 2025-05-23
Form Type: 424B3
Source: 0001193125-25-125499
Chunk: 11

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-05-23
Form: 424B3
Chunk 11
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 statement of TuHURA and Kineta
under Section 14(a) of the Exchange Act and notices of meetings with respect to each of the TuHURA and Kineta special meetings.

TuHURA has supplied all information contained in this joint proxy statement/prospectus relating to TuHURA and Merger Subs, and Kineta has
supplied all such information relating to Kineta. TuHURA and Kineta have both contributed to the information related to the Mergers contained in this joint proxy statement/prospectus.

You should rely only on the information contained in this joint proxy statement/prospectus. TuHURA and Kineta have not authorized anyone to
provide you with information that is different from that contained in this joint proxy statement/prospectus. This joint proxy statement/prospectus is dated May 23, 2025, and you should not assume that the information contained in this joint
proxy statement/prospectus is accurate as of any date other than such date unless otherwise specifically provided herein.

Neither the
mailing of this joint proxy statement/prospectus to TuHURA or Kineta stockholders nor the issuance by TuHURA of shares of TuHURA Common Stock pursuant to the Merger Agreement will create any implication to the contrary.

This joint proxy statement/prospectus does not constitute an offer to sell, or a solicitation of an offer to buy, any securities, or the solicitation of a proxy, in any jurisdiction to or from any person to whom it is unlawful to make any such offer or solicitation in such jurisdiction.

TABLE OF CONTENTS

|                                                                        |     | Page |     |
| FREQUENTLY USED TERMS                                                  |     |      |   1 |
| QUESTIONS AND ANSWERS                                                  |     |      |  11 |
| SUMMARY                                                                |     |      |  25 |
| COMPARATIVE PER SHARE MARKET PRICE DATA AND DIVIDEND                   
 INFORMATION                                                            |     |      |  43 |
| CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS              |     |      |  45 |
| RISK FACTORS                                                           |     |      |  46 |
| RISKS RELATING TO TUHURA                                               |     |      |  55 |
| RISKS RELATING TO KINETA                                               |     |      |  98 |
| THE PARTIES TO THE MERGERS                                             |     |      | 174 |
| THE TUHURA SPECIAL MEETING                                             |