Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 27

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 27
---
 to vote your shares in accordance with the instructions provided to you. Please check the voting form used by your bank, broker or other nominee. |

| Q: | What is a “broker non-vote”? |

| A: | Banks, brokers and other nominees who hold shares in street name for a beneficial owner of those shares     
 typically have the authority to vote in their discretion on “routine” proposals when they have not received |

11

| instructions from beneficial owners. However, banks, brokers and other nominees are not allowed to exercise their voting discretion with respect to the approval of matters determined to be “non-routine” without specific instructions from the beneficial owner. |

A broker non-voteoccurs when a bank, broker or other nominee is not permitted to vote on a “non-routine”matter without instructions from the beneficial owner of the shares and the beneficial owner fails to provide the bank, broker or other nominee with such instructions. Broker non-votesonly count toward a quorum if at least one (1) proposal is presented with respect to which the bank, broker or other nominee has discretionary authority. It is expected that all proposals to be voted on at each of the Fifth Third special meeting and the Comerica special meeting will be “non-routine”matters, and, as such, broker non-votes,if any, will not be counted as present and entitled to vote for purposes of determining a quorum at the Fifth Third special meeting or the Comerica special meeting. If your shares are held by a bank, broker or other nominee in “street name,” such entity will vote your shares only if you provide instructions on how to vote by complying with the instructions provided to you by your bank, broker or other nominee with this joint proxy statement/prospectus. If you are a beneficial owner of Fifth Third common stock or Fifth Third voting preferred shares and you do not instruct your bank, broker or other nominee on how to vote your shares of Fifth Third common stock and Fifth Third voting preferred shares:

| • |     | Fifth Third stock issuance proposal: your bank, broker or other nominee may not vote your shares on the                               
 Fifth Third stock issuance proposal, which broker non-votes, if any, will have the same effect as a vote “AGAINST” such proposal; and |

| • |     | Fifth Third adjournment proposal: your bank, broker or other nominee may not vote your shares on the Fifth       
 Third adjournment proposal, which broker non-votes, if any, will have