Company: SNY
Filing Date: 2025-10-29
Form Type: 424B5
Source: 0001193125-25-255563
Chunk: 28

Company: Sanofi
Filing Date: 2025-10-29
Form: 424B5
Chunk 28
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 plan de sauvegarde) or a draft judicial reorganization plan ( projet de plan de redressement) with respect to Sanofi S.A. which:

| • |     | would have to take into account any known subordination/intercreditor agreements entered into by the creditors                                                            
 prior to the opening of the proceedings (as the case may be) and could be subject to any deviation from the absolute priority rule as may be authorized by the court; and |

| • |     | would provide the terms and conditions of the debt restructuring (which could in particular provide for a                        
 rescheduling and/or a partial or full write-off of the amount due under the notes and/or debt-to-equity swaps and/or the sale of 
 part of the business) in compliance with the creditors’ best—interest – test (critère du meilleur intérêt des créanciers).       |

Should the plan be approved by any class of Affected Parties by a majority vote, consisting of at least two-thirdsof the voting rights expressed within that class, and provided certain requirements are met, the plan would be imposed upon the dissenting creditors of such class through a cram-down. Should the plan be rejected by one or more such class(es), the competent French court may nevertheless adopt it and impose it upon the dissenting creditors and classes (through a cross-class cram down sanctioned by such court), provided certain requirements are met such as compliance with the absolute priority rule called under French law règle de la priorité absolue(subject, however, to the court’s possible authorization to deviate from the absolute priority rule). However, if the debtor’s recovery is clearly impossible, the relevant court can order a sale of the business as a going concern or open or, as the case may be, convert the then outstanding proceedings into, judicial liquidation proceedings ( liquidation judiciaire). Practically, it is highly unlikely that the holders of the notes, as unsecured creditors, could be repaid in full for their claims within those contexts. Therefore, certain provisions of the indenture may not be enforced or enforceable by the trustee or holders of notes issued under this prospectus supplement and the attached prospectus in case of opening of court-assisted pre-insolvencyproceedings or court-administered insolvency proceedings under French law regarding Sanofi S.A. Moreover, the commencement of insolvency proceedings against Sanofi S.A. would have a material adverse effect on the market value of the notes. As a consequence, any decision(s) taken