Company: QXO-PB
Filing Date: 2025-06-25
Form Type: 424B5
Source: 0001104659-25-062233
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Company: QXO, Inc.
Filing Date: 2025-06-25
Form: 424B5
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TABLE OF CONTENTS The information in this prospectus supplement is not complete and may be changed. This prospectus supplement and the accompanying prospectus are not an offer to sell these securities and they are not soliciting an offer to buy these securities in any jurisdiction where the offer or sale is not permitted.

Filed Pursuant to Rule 424(b)(5) Registration No. 333-281084 Subject to Completion, Dated June 24, 2025 PRELIMINARY PROSPECTUS SUPPLEMENT
(To Prospectus dated July 29, 2024) $2,000,000,000 Common Stock QXO, Inc. is offering $2,000,000,000 of shares of its common stock, par value $0.00001 per share (“Common Stock”), pursuant to this prospectus supplement and the accompanying prospectus. We intend to use the net proceeds of this offering for general corporate purposes, which may include, among other things, funding future acquisitions of businesses. See “Use of Proceeds.” Our Common Stock is listed on the New York Stock Exchange (“NYSE”) under the symbol “QXO.” On June 23, 2025, the last reported sale price of our Common Stock on the NYSE was $24.12 per share. See “Risk Factors” beginning on page S-13of this prospectus supplement and in the documents incorporated by reference in this prospectus supplement to read about factors you should consider before buying shares of our Common Stock. Neither the Securities and Exchange Commission (the “SEC”) nor any state securities commission has approved or disapproved of these securities or determined if this prospectus supplement or the accompanying prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

| ​                                            | ​ | ​ | Per Share |   |     |   | ​ | ​ | Total |   |   |   | ​ |
|:---------------------------------------------|:--|:--|:----------|:--|:----|:--|:--|:--|:------|:--|:--|:--|:--|
| Public offering price(1)                     | ​ | ​ | ​         | $ |     | ​ | ​ | ​ | ​     | $ |   | ​ | ​ |
| Underwriting discounts and commissions(1)(2) | ​ | ​ | ​         | $ |     | ​ | ​ | ​ | ​     | $ |   | ​ | ​ |
| Proceeds before