Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 416

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 416
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 time as required by the SEC, an annual report on Form 20-F containing financial statements audited
by an independent registered public accounting firm, and will submit to the SEC, on Form 6-K, unaudited interim financial information
for the first six months of each fiscal year.

The Company maintains a corporate
website at www.aptorumgroup.com. Information contained on, or that can be accessed through, the Company’s website does not constitute
a part of this prospectus.

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INCORPORATION OF CERTAIN INFORMATION BY REFERENCE</div>

This registration statement
incorporates by reference important business and financial information about the Company that is not included in or delivered with this
document. The information incorporated by reference is considered to be part of this prospectus, and the SEC allows
us to “incorporate by reference” the information we file with it, which means that we can disclose important information to
you by referring you to those documents instead of having to repeat the information in this prospectus. Any statement contained in any
document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded
for purposes of this prospectus to the extent that a statement contained in or omitted from this prospectus or any accompanying prospectus
supplement, or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein,
modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded,
to constitute a part of this prospectus.

This prospectus incorporates
by reference the documents listed below:

| (1) | the Company’s Annual Report on Form 20-F for the fiscal year ended December 31, 2024, filed with the SEC on April 30, 2025, which contains our audited consolidated financial statements for the most recent fiscal year for which those statements have been filed; |
| (2) | the Company’s Current Reports on Form 6-K and 6-K/A, filed with the SEC on July 22, 2025, September 10, 2025, October 3, 2025, October 8, 2025, October 15, 2025 and October 16, 2025;                                                                               |
| (3) | the description of our Ordinary Shares contained in our Registration Statement on Form 8-A filed with the SEC on December 14,