Company: BLTE
Filing Date: 2025-03-21
Form Type: S-8
Source: 0001104659-25-026633
Chunk: 0

Company: BELITE BIO, INC
Filing Date: 2025-03-21
Form: S-8
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission onMarch 21, 2025</div>

Registration No. 333-

<div align='center'>SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM S-8

REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933

Belite Bio, Inc

(Exact Name of Registrant as Specified in Its Charter)</div>

| Cayman Islands                  |     | Not Applicable        |
| (State or Other Jurisdiction of 
 Incorporation or Organization)  |     | -I.R.S. Employer      
 Identification Number |

<div align='center'>12750 High Bluff Drive Suite 475,San Diego, CA 92130
Telephone: +1-858-246-6240

(Address, Including Zip Code, and Telephone
Number, Including Area Code, of Registrant’s Principal Executive Offices)

Belite Bio, Inc 2022 Performance Incentive Plan

(Full title of the plans)

Puglisi & Associates

850 Library Avenue, Suite 204

Newark, Delaware 19711

(302) 738-6680

(Name, Address, Including Zip Code, and Telephone
Number, Including Area Code, of Agent For Service)</div>

|                                    |     | Copies to: |                        |
| Yu-Hsin Lin                        
 Belite Bio, Inc                    
 12750 High Bluff Drive, Suite 475, 
 San Diego, CA 92130                
 +1-858-246-6240                    |     |            | Portia Ku, Esq.        
 Vincent Lin, Esq.      
 O’Melveny & Myers LLP  
 JC Plaza, 12th Floor   
 1225 Nanjing Road West 
 Shanghai 200040        
 +86-21-2307-7000       |

Indicate by check mark whether the registrant
is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company.
See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company”
and “emerging growth company” in Rule 12b-2 of the Exchange Act:

| Large accelerated filer ¨ |     | Accelerated filer ¨         |
| Non-accelerated filer x   |     | Smaller reporting company ¨ |
|                           |