Company: SION
Filing Date: 2025-08-11
Form Type: 10-Q
Source: 0002036042-25-000047
Chunk: 295

Company: Sionna Therapeutics, Inc.
Filing Date: 2025-08-11
Form: 10-Q
Item: Part II, Item 2
Chunk 295
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es-Oxley Act of 2002.101.INSInline XBRL Instance Document101.SCHInline XBRL Taxonomy Extension Schema With Embedded Linkbase Documents104Cover Page Interactive Data File (embedded with the Inline XBRL document)

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*Filed herewith.

+The certification furnished in Exhibit 32.1 hereto is deemed to be furnished with this Quarterly Report and will not be deemed to be "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, except to the extent that the Registrant specifically incorporates it by reference.

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SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

SIONNA THERAPEUTICS, INC.Date: August 11, 2025By:/s/Michael CloonanName:Michael Cloonan, M.B.A.Title:President and Chief Executive Officer(Principal Executive Officer)Date: August 11, 2025By:/s/Elena RidloffName:Elena Ridloff, C.F.A.Title:Chief Financial Officer and Head of Corporate Development(Principal Financial Officer and Principal Accounting Officer)

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