Company: RPTX
Filing Date: 2025-04-29
Form Type: DEF 14A
Source: 0001193125-25-103764
Chunk: 4

Company: Repare Therapeutics Inc.
Filing Date: 2025-04-29
Form: DEF 14A
Chunk 4
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 instructions on how to attend the virtual Annual Meeting, please see the instructions at www.proxydocs.com/RPTXand on page 2 of this proxy statement.

Unless otherwise noted or the context otherwise requires, all information provided in this proxy statement is given as at April 29, 2025. In this proxy statement, we refer to Repare Therapeutics Inc. as “Repare,” “the Company,” “we” or “us” and the board of directors of Repare as “our board of directors.”

The Annual Report, which contains financial statements as of December 31, 2024 and 2023 and for each of the two fiscal years ended December 31, 2024 and our “Management’s Discussion and Analysis of Financial Condition and Results of Operations,” accompanies this proxy statement and is, together with additional information relating to the Company, available on SEDAR+ at www.sedarplus.caand on EDGAR at www.sec.gov. You also may obtain a copy of the Annual Report without charge by writing to our Secretary at Repare Therapeutics Inc., 7171 Frederick-Banting, Building 2, Suite 270, St-Laurent, Québec, Canada H4S 1Z9, Attention: Secretary or by emailing investor@reparerx.com. Financial information relating to the Company is provided in our audited financial statements as of December 31, 2024 and 2023 and for each of the two fiscal years ended December 31, 2024.

#### TABLE OF CONTENTSPageQUESTIONS AND ANSWERS ABOUT THESE PROXY MATERIALS AND VOTING1PROPOSAL 1 ELECTION OF DIRECTORS9INFORMATION REGARDING DIRECTORS AND DIRECTOR NOMINEES10INFORMATION REGARDING THE BOARD OF DIRECTORS AND CORPORATE GOVERNANCE13PROPOSAL 2 APPROVAL, ON ANON-BINDING,ADVISORY BASIS, OF THE COMPENSATION OF OUR NAMED EXECUTIVE OFFICERS25EXECUTIVE OFFICERS26EXECUTIVE COMPENSATION27PAY VERSUS PERFORMANCE44NON-EMPLOYEEDIRECTOR COMPENSATION47PROPOSAL 3 APPOINTMENT OF ERNST & YOUNG LLP AS OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM50SECURITY OWNERSHIP OF CERTAIN BENEFICAL OWNERS AND MANAGEMENT52TRANSACTIONS WITH RELATED PERSONS AND INDEMNIFICATION56HOUSEHOLDING OF PROXY MATERIALS58OTHER MATTERS59i