Company: CNTB
Filing Date: 2025-06-10
Form Type: F-3
Source: 0001193125-25-138482
Chunk: 81

Company: Connect Biopharma Holdings Ltd
Filing Date: 2025-06-10
Form: F-3
Chunk 81
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 subject to limitations on transfers of our ADSs. |

| • |     | Investors’ rights to pursue claims against the depositary as a holder of ADSs are limited by the terms of 
 the deposit agreement.                                                                                    |

| • |     | ADS holders may not be entitled to a jury trial with respect to claims arising under the deposit agreement, 
 which could result in less favorable outcomes to the plaintiff(s) in any such action.                       |

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| • |     | Investors may face difficulties in protecting the interests of investors, and the ability to protect the      
 rights of investors through U.S. courts may be limited, because we are incorporated under Cayman Islands law. |

| • |     | We may experience material weaknesses in our internal control over financial reporting in the future. If so,                                                                                                                                       
 or if we otherwise fail to maintain proper and effective internal control over financial reporting, our ability to produce accurate and timely consolidated financial statements could be impaired, investors may lose confidence in our financial 
 reporting and the trading price of our ADSs may decline.                                                                                                                                                                                           |

| • |     | Our amended and restated memorandum and articles of association contain anti-takeover provisions that could                                                                        
 discourage a third party from acquiring us, which could limit our shareholders’ opportunity to sell their shares, including ordinary shares represented by our ADSs, at a premium. |

| • |     | We could be subject to securities class action litigation. |

| • |     | If securities or industry analysts do not continue to publish research or publish inaccurate or unfavorable 
 research about our business, the market price for our ADSs and trading volume could decline.                |

| • |     | The increasing use of social media platforms presents new risks and challenges. |

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THE OFFERING

| ADSs offered by us in the offering | ADSs, each ADS representing one Ordinary Share, par value $0.000174 per share, having an aggregate offering price of up to |

$150,000,000.

| Subject to the terms of the Deposit Agreement and in compliance with the relevant requirements set out in the                                                                                                                                           
 prospectus, you may turn in your ADSs to the Depositary for cancellation and withdrawal of the Ordinary Shares underlying your ADSs. The Depositary will charge you fees for such cancellations pursuant to the Deposit Agreement. You should carefully 
 read the “Description of American Depositary Shares” section of this prospectus and the Deposit Agreement to better understand the terms of the ADSs.                                                                                                   |

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