Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119831
Chunk: 97

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 97
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 in bringing our product candidates to market and be precluded from manufacturing or selling our product candidates. We cannot be certain that others have not filed patent applications for technology covered by our pending applications, or that we were the first to invent the technology, because:

| • |     | some patent applications in the United States may be maintained in secrecy until the patents are issued; |

| • |     | patent applications in the United States and elsewhere can be pending for many years before issuance, or 
 unintentionally abandoned patents or applications can be revived;                                        |

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| • |     | pending patent applications that have been published can, subject to certain limitations, be later amended in a 
 manner that could cover our technologies, our product candidates or the use of our product candidates;          |

| • |     | identification of third-party patent rights that may be relevant to our technology is difficult because patent                                             
 searching is imperfect due to differences in terminology among patents, incomplete databases and the difficulty in assessing the meaning of patent claims; |

| • |     | patent applications in the United States are typically not published until 18 months after the priority date; and |

| • |     | publications in the scientific literature often lag behind actual discoveries. |

Furthermore, the scope of a patent claim is determined by an interpretation of the law, the written disclosure in a patent and the patent’s prosecution history and can involve other factors such as expert opinion. Our interpretation of the relevance or the scope of claims in a patent or a pending application may be incorrect, which may negatively impact our ability to market our products. Further, we may incorrectly determine that our technologies, products, or product candidates are not covered by a third-party patent or may incorrectly predict whether a third party’s pending patent application will issue with claims of relevant scope. Our determination of the expiration date of any patent in the United States or internationally that we consider relevant may be incorrect, which may negatively impact our ability to develop and market our products or product candidates. Our competitors may have filed, and may in the future file, patent applications covering technology similar to ours, and others may have or obtain patents or proprietary rights that could limit our ability to make, use, sell, offer for sale or import our product candidates and future approved products or impair our competitive position. Numerous third-party U.S. and foreign issued patents and pending patent applications exist in the fields in which we are developing product candidates. There may be third-party patents or patent applications with claims to materials, formulations, methods of manufacture or methods for