Company: SNY
Filing Date: 2025-10-27
Form Type: 424B5
Source: 0001193125-25-250786
Chunk: 45

Company: Sanofi
Filing Date: 2025-10-27
Form: 424B5
Chunk 45
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 of the Notes of the applicable series to be redeemed by the Issuer or by the Trustee on its behalf.

In the case of a partial redemption, selection of the Notes for redemption will be made pro rata, by lot or by such other method as the
Trustee in its sole discretion deems appropriate and fair. No notes of a principal amount of $2,000 or less will be redeemed in part. If any note is to be redeemed in part only, the notice of redemption that relates to the note will state the
portion of the principal amount of the note to be redeemed. A new note in a principal amount equal to the unredeemed portion of the note will be issued in the name of the holder of the note upon surrender for cancellation of the original note. For
so long as the notes are held by DTC, Euroclear or Clearstream (or another depositary), the redemption of the notes shall be done in accordance with the policies and procedures of the depositary.

Unless the Issuer defaults in payment of the redemption price, on and after the redemption date, interest will cease to accrue on the notes or
the portions thereof called for redemption.

Tax Redemption

We may redeem the Notes as described under “Description of Debt Securities We May Offer — Special Situations — Optional Tax
Redemption” in the attached prospectus.

Covenants

Holders of the Notes will benefit from certain covenants contained in the Indenture and affecting our ability to incur liens and merge with
other entities. You should read the information under the heading “Description of Debt Securities We May Offer — Special Situations — Negative Pledge” and “Description of Debt Securities We May Offer — Special
Situations — Mergers and Similar Events” in the attached prospectus.

S-34

Special Situations Negative Pledge With respect to the Notes offered hereby, the information in the second paragraph under the heading “Description of Debt Securities We May Offer — Special Situations — Negative Pledge” in the attached prospectus is hereby replaced by the following: For the purpose of this covenant, “Relevant Indebtedness” means any indebtedness for borrowed money, whether present or future (including, without limitation, any contingent obligation, any surety or other obligation), which is for, or in respect of, or represented by any bonds, debentures, or other form of debt securities capable of being listed, quoted or ordinarily dealt in on any stock exchange, over-the-countermarket or