Company: SCLXW
Filing Date: 2025-04-01
Form Type: S-8
Source: 0001193125-25-069295
Chunk: 2

Company: Scilex Holding Co
Filing Date: 2025-04-01
Form: S-8
Chunk 2
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 to any portion of any future annual or quarterly report to stockholders or document or current report furnished under Items 2.02 or 7.01 of Form 8-Kthat is not deemed filed under such provisions. For the purposes of this Registration Statement, any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded to the extent that a statement contained herein or in any other subsequently filed document that also is or is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement. You should rely only on the information provided or incorporated by reference in this Registration Statement or any related prospectus. The Registrant has not authorized anyone to provide you with different information. You should not assume that the information in this Registration Statement or any related prospectus is accurate as of any date other than the date on the front of the document. You may contact the Registrant in writing or orally to request copies of the above-referenced filings, without charge (excluding exhibits to such documents unless such exhibits are specifically incorporated by reference into the information incorporated into this Registration Statement). Requests for such information should be directed to: Scilex Holding Company 960 San Antonio Road Palo Alto, CA 94303 Attn: Investor Relations Phone: (650) 516-4310 II-1

| ITEM 4. | DESCRIPTION OF SECURITIES. |

Not applicable.

| ITEM 5. | INTERESTS OF NAMED EXPERTS AND COUNSEL. |

Not applicable.

| ITEM 6. | INDEMNIFICATION OF DIRECTORS AND OFFICERS. |

Section 102 of the General Corporation Law of the State of Delaware (the “DGCL”) permits a corporation to eliminate or limit the personal liability of directors and officers of a corporation to the corporation or its stockholders for monetary damages for a breach of fiduciary duty as a director or officer, except where the director or officer breached his or her duty of loyalty to the corporation or its stockholders, failed to act in good faith, engaged in intentional misconduct or knowingly violated a law, authorized the payment of a dividend or approved a stock repurchase or redemption in violation of the DGCL or derived an improper personal benefit, or, with respect to any officer, any action by or in the right of the corporation. The Registrant’s rest