Company: RPTX
Filing Date: 2025-12-03
Form Type: PREM14A
Source: 0001193125-25-306948
Chunk: 111

Company: Repare Therapeutics Inc.
Filing Date: 2025-12-03
Form: PREM14A
Chunk 111
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 live during the Special Meeting. |

| • |     | You may submit questions and comments electronically through the meeting portal during the Special Meeting. 
 Management will respond to appropriate questions in the order received.                                     |

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| • |     | Please direct all questions to Thomas Civik, our Board Chairperson, or Steve Forte, our President, Chief   
 Executive Officer and Chief Financial Officer, who has been appointed as Secretary of the Special Meeting. |

| • |     | Please include your name and affiliation, if any, when submitting a question or comment. |

| • |     | Limit your remarks to one brief question or comment that is relevant to the Special Meeting and/or our business. 
 Up to one minute will be allocated to each submitted question or comment.                                        |

| • |     | Questions may be grouped by topic by our management. |

| • |     | Questions may also be ruled as out of order if they are, among other things, irrelevant to our business, related                                                           
 to pending or threatened litigation, disorderly, repetitious of statements already made, or in furtherance of the speaker’s own personal, political or business interests. |

Appointment of a Third Party as Proxy The following applies to Shareholders who wish to appoint someone as their proxyholder other than the Persons designated in the enclosed form of proxy or voting instruction form. This includes non-registeredShareholders who wish to appoint themselves as proxyholder to attend, participate or vote at the Special Meeting. Shareholders of record who wish to appoint a third-party proxyholder other than the persons identified on the proxy card to attend, participate or vote at the Special Meeting as their proxy and vote their shares MUST submit their proxy card appointing such third-party proxyholder AND register the third-party proxyholder, as described below. Registering your proxyholder is an additional step to be completed AFTER you have submitted your proxy. Failure to register the proxyholder will result in the proxyholder not receiving access to attend, participate or vote at the Special Meeting. Step 1:To appoint a third-party proxyholder, insert such person’s name and email in the blank space provided in the proxy card and follow the instructions for submitting such proxy card by mail. This must be completed prior to registering such proxyholder, which is an additional step to be completed once you have submitted your proxy card. Step 2:To register a duly appointed third-party proxyholder, shareholders MUST provide the proxyholder contact information requested by BetaNXT, Inc. in order to be provided with