Company: APM
Filing Date: 2025-11-17
Form Type: F-1
Source: 0001213900-25-111548
Chunk: 124

Company: Aptorum Group Ltd
Filing Date: 2025-11-17
Form: F-1
Chunk 124
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 | changes in revenue or earnings estimates, or changes in recommendations 
 or withdrawal of research coverage, by equity research analysts;        |

| ● | speculation in the press or investment community; |

| ● | the failure of research analysts to cover our securities; |

| ● | sales of Aptorum Class A ordinary shares by us or other    
 shareholders, or the perception that such sales may occur; |

| ● | changes in accounting principles, policies, guidance, interpretations 
 or standards;                                                         |

| ● | additions or departures of key management personnel; |

| ● | actions by our shareholders; |

| ● | domestic and international economic, legal and regulatory factors 
 unrelated to our performance; and                                 |

| ● | the realization of any risks describes under this “Risk 
 Factors” section.                                       |

The stock markets in general have experienced extreme volatility that has often been unrelated to the operating performance of particular companies. These broad market fluctuations may adversely affect the trading price of Aptorum Class A ordinary shares. Securities class action litigation has often been instituted against companies following periods of volatility in the overall market and in the market price of a company’s securities. Such litigation, if instituted against us, could result in very substantial costs, divert our management’s attention and resources and harm our business, operating results and financial condition. 68 Risks Related to Aptorum’s Doing Business in Hong Kong Our company currently does not have operations in mainland China. PRC laws and regulations may be applicable to a company such as us in the future, the application of such laws and regulations may have a material adverse impact on our business, financial condition and results of operations and our ability to offer or continue to offer securities to investors, any of which may cause the value of Aptorum Class A ordinary shares, to significantly decline or become worthless. See the following risk factors of “Our business, financial condition and results of operations, and/or the value of Aptorum Class A ordinary shares or our ability to offer or continue to offer securities to investors may be materially and adversely affected to the extent the laws and regulations of the PRC become applicable to a company such as us” and “The PRC government exerts substantial influence and discretion over the manner in which companies incorporated under the laws of PRC must conduct their business activities. If we were to become subject to such direct influence or discretion, it may result in a material change in our operations and/or the value of Aptorum Class A ordinary shares, which would materially affect the interests of investors.” Political risks associated with conducting business