Company: NCEL
Filing Date: 2025-05-16
Form Type: 20-F
Source: 0001213900-25-044868
Chunk: 177

Company: NewcelX Ltd.
Filing Date: 2025-05-16
Form: 20-F
Item: Item 4
Chunk 177
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 reported that 6.1 million, or 9.4%, of children and adolescents in the United States have ever been diagnosed
with ADHD and 5.4 million, or 8.4%, have a current diagnosis, and 62% take medication, while 47% receive behavioral therapy and 23% receive
no treatment at all. According to the CDC’s 2022 National Survey of Children’s Health, approximately 1 in 9 U. S. children
(11.4%, or 7.1 million) have been diagnosed with ADHD at some point, and 10.5% (6.5 million) currently have the condition. Among those
with current ADHD, 58.1% have moderate or severe symptoms, and 77.9% have at least one other co-occurring disorder. Roughly half (53.6%)
are being treated with medication, while nearly one-third are not receiving any ADHD-specific treatment at all. In terms of treatment,
53.6% were receiving medication, 44.4% had received behavioral therapy in the past year, and nearly one-third (30.1%) were not receiving
any ADHD-specific treatment. Between 2016 and 2022, the number of U. S. children diagnosed with ADHD increased by more than one million,
reflecting a significant rise in prevalence.. Additionally, ADHD is the second most impactful condition affecting children and adolescent
health in the United States, as measured by the Blue Cross Blue Shield Health Index, and children diagnosed with ADHD struggle with paying
attention, controlling impulses and being overly active. Social skills in children with ADHD often are significantly impaired. Problems
with inattention may limit opportunities to acquire social skills or to attend to social cues necessary for effective social interaction,
making it difficult to form friendships. Hyperactive and impulsive behaviors may result in peer rejection. The negative consequences of
impaired social function, such as poor self-esteem, increased risk for depression and anxiety, may be long standing.

Once believed to only affect
children and adolescents, ADHD is now well understood to be a lifespan disorder that persists into adulthood in up to 65% of patients
affecting 1 out of 30 adults worldwide, as disclosed by the ADHD Institute, an educational platform developed and funded by Takeda, and,
based on our own assessments of data from the U. S. census Bureau, there are approximately 11 million adults in the United States with
ADHD. Research firm Global