Company: SCLXW
Filing Date: 2025-02-14
Form Type: PRE 14A
Source: 0001193125-25-027244
Chunk: 42

Company: Scilex Holding Co
Filing Date: 2025-02-14
Form: PRE 14A
Chunk 42
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 shares of Common Stock into which the shares of Common Stock represented by the Old Certificates shall have been reclassified, changed and combined, subject to the treatment of fractional shares as described above.”

| D. | This Certificate of Amendment shall be effective at 12:01 a.m. Eastern Time on ____________, 2025. |

| 1 | The Board of Directors of the Corporation adopted resolutions approving 17 separate amendments to the                                                                                                                                                    
 Restated Certificate of Incorporation. These amendments approve the combination of any whole number of shares of Common Stock between and including 14 and 30 into one share of Common Stock. By approving Proposal No. 1, you are approving each of the 
 17 amendments proposed by the Board of Directors. The Certificate of Amendment filed with the Secretary of State of the State of Delaware will include only that amendment determined by the Board of Directors to be in the best interests of the       
 Corporation and its stockholders. The other 16 proposed amendments will be abandoned pursuant to Section 242(c) of the General Corporation Law of the State of Delaware. The Board of Directors may also elect not to do any reverse stock split,        
 pursuant to which all 17 proposed amendments will be abandoned.                                                                                                                                                                                          |

A-1

IN WITNESS WHEREOF, the Corporation has caused this Certificate of Amendment to the Restated Certificate of Incorporation to be signed by its Chief Executive Officer and President on _____________, 2025.

| SCILEX HOLDING COMPANY |     |                                       |
| By:                    |     |                                       |
|                        |     | Jaisim Shah                           |
|                        |     | Chief Executive Officer and President |

A-2

| SCILEX HOLDING COMPANY 960 SAN ANTONIO RD 
 PALO ALTO, CA 94303                       |     | VOTE BY INTERNET                                                                                                                                                                                                                                   
 Before The Meeting - Go to www.proxyvote.com or scan the QR Barcode above                                                                                                                                                                          
 Use the Internet to transmit your voting instructions and for                                                                                                                                                                                      
 electronic delivery of information up until 11:59 p.m. Eastern Time on March 18, 2025. Have your proxy card in hand when you access the web site and follow the instructions to obtain your records and to create an electronic voting instruction 
 form.                                                                                                                                                                                                                                              
 During The Meeting - Go to www.virtualshareholdermeeting.com/SCLX2025SM                                                                                                                                                                            
 You may attend the meeting via the Internet and vote during the                                                                                                                                                                                    
 meeting. Have the information that is