Company: NCNA
Filing Date: 2025-06-18
Form Type: 6-K
Source: 0001193125-25-142535
Chunk: 4

Company: NuCana plc
Filing Date: 2025-06-18
Form: 6-K
Chunk 4
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 to the Company’s existing share option schemes. The options will have an exercise price ranging from market value at date of grant to the par value of each ordinary share. These options
will be granted in line with the Company’s current remuneration policies on vesting with vesting over up to 4 years for elements of the option grant.

The information contained in this Form 6-K is hereby incorporated by reference into the Company’s
Registration Statement on Form S-8 (File No. 333-223476) and Registration Statement on Form S-8 (File No. 333-248135).

Forward Looking Statements

This Form 6-K contains forward-looking statements. These statements are based on the current beliefs
and expectations of the management of the Company and/or its affiliates. These forward-looking statements may include, but are not limited to, statements regarding the trading price of the Company’s ADSs, the Company’s ability to benefit
from the executives’ experience and expertise, and the Company’s option schemes. The Company’s estimates, projections and other forward-looking statements are based on management’s current assumptions and expectations of future
events and trends, which affect or may affect the Company’s business, strategy, operations, or financial

performance, and inherently involve significant known and unknown risks and uncertainties. Actual results and the timing of events could differ materially from those anticipated in such
forward-looking statements as a result of many risks and uncertainties, which include, the impact of the ongoing, global political and economic conflicts on the Company’s business and the global economy, and general market conditions. Other
factors that may cause actual results to differ from those expressed or implied in such forward-looking statements are described in the Company’s U.S. Securities and Exchange Commission (“SEC”) filings and reports (Commission File No. 001-38215), including the Company’s Annual Report on Form 20-F filed with the SEC on March 20, 2025 and the “Supplemental Risk Factors” filed with
our Form 6-Ks from time to time. All statements other than statements of historical fact are forward-looking statements. The words “believe,” “may,” “might,” “could,”
“will,” “aim,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “plan,” or the negative of those terms, and similar expressions that convey uncertainty of
future events or outcomes are intended to identify estimates, projections, and other forward-looking statements. Estimates, projections, and other