Company: HRTX
Filing Date: 2025-09-09
Form Type: S-3
Source: 0000950170-25-113834
Chunk: 0

Company: HERON THERAPEUTICS, INC. /DE/
Filing Date: 2025-09-09
Form: S-3
Chunk 0
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As filed with the Securities and Exchange Commission on September 9, 2025 Registration Statement No. 333- UNITED STATES
SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 _______________________ FORM S-3 REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933 _______________________ HERON THERAPEUTICS, INC. (Exact Name of Registrant as Specified in Its Charter) _______________________

| Delaware                        |     | 94-2875566         |
| (State or other jurisdiction of 
 incorporation or organization)  |     | -I.R.S. Employer   
 Identification No. |

100 Regency Forest Drive, Suite 300
Cary, North Carolina
Tel: (858) 251-4400 (Address, including zip code, and telephone number, including
area code, of registrant’s principal executive offices) _______________________ Craig Collard
Chief Executive Officer
Heron Therapeutics, Inc.
100 Regency Forest Drive, Suite 300
Cary, North Carolina 27518
Tel: (858) 251-4400 (Name, address, including zip code, and telephone number including area code, of agents for service) _______________________ Copies to:
Andrew P. Gilbert, Esq. Emilio Ragosa, Esq.
DLA Piper LLP (US)
51 John F. Kennedy Parkway
Short Hills, New Jersey 07078
Tel: (973) 520-2550 _______________________ Approximate date of commencement of proposed sale to the public: From time to time after the effectiveness of this registration statement. If the only securities being registered on this form are being offered pursuant to dividend or interest reinvestment plans, please check the following box. ¨ If any of the securities being registered on this form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, as amended, other than securities offered only in connection with dividend or interest reinvestment plans, check the following box. x

If this form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ¨ If this form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering