Company: GHRS
Filing Date: 2025-02-05
Form Type: 424B5
Source: 0001140361-25-003183
Chunk: 65

Company: GH Research PLC
Filing Date: 2025-02-05
Form: 424B5
Chunk 65
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 Powers Subject to the Constitution and the Irish Companies Act, our Board of Directors may exercise all of our powers to:

| (i) | borrow money; |

| (ii) | indemnify and guarantee; |

| (iii) | mortgage or charge; |

| (iv) | create and issue debentures and other securities; and |

| (v) | give security either outright or as collateral security for any of our debt, liability or obligation or any of a third party. |

Uncertificated Shares Shares in an Irish public limited company such as ours can, in principle, be issued and held either in a so-called certificated (i.e., hard copy share certificates are issued to shareholders) or a so-called uncertificated (i.e., dematerialized) form. All shareholders’ names must be entered into the register of members maintained by an Irish public limited company in order to acquire legal title to the shares. To make shares in an Irish public limited company deliverable for trading on an exchange, the shares are required to be issued in uncertificated form. Amendment of Constitution Irish company law requires a special resolution of our shareholders (approval by not less than 75% of the votes cast at a general meeting of our shareholders) to approve any amendments to the Constitution. Anti-Takeover Provisions of Irish Law Irish Takeover Rules and Substantial Acquisition Rules A transaction in which a third party seeks to acquire 30% or more of our voting rights and any other acquisitions of our securities will be governed by the Irish Takeover Panel Act 1997 and the Irish Takeover Rules made thereunder, the Irish Takeover Panel Act, 1997, Takeover Rules, 2022, or the Irish Takeover Rules, and will be regulated by the Irish Takeover Panel. The general principles of the Irish Takeover Rules, or the General Principles, and certain important aspects of the Irish Takeover Rules are described below.

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General Principles The Irish Takeover Rules are built on the following General Principles which will apply to any transaction regulated by the Irish Takeover Panel:

| (i) | in the event of an offer, all holders of securities of the target company must be afforded equivalent treatment and, if a person acquires control of a company, the other holders of securities must be protected; |

| (ii) | the holders of securities in the target company must have sufficient time and information to enable them to reach a properly informed decision on the offer; where it