Company: APM
Filing Date: 2025-10-14
Form Type: 424B5
Source: 0001213900-25-098635
Chunk: 84

Company: Aptorum Group Ltd
Filing Date: 2025-10-14
Form: 424B5
Chunk 84
---
 SECONDARY OFFERING The secondary offering of this prospectus relates to the offer and resale by the Selling Shareholders of an aggregate of 540,540 Class A Ordinary Shares, all of which are issuable upon the exercise of 540,540 Selling Shareholder Warrants. All of the Class A Ordinary Shares underlying the Resale Warrants, when sold, will be sold by the Selling Shareholders. The Selling Shareholders may sell the Class A Ordinary Shares from time to time at prevailing market prices or at privately negotiated prices.

| Class A Ordinary Shares underlying Resale Warrants     
 offered by the Selling Shareholders                    |     | 540,540 Class A Ordinary Shares underlying the Selling Shareholder Warrants                                                                                                                                                                                                                                                                                                                                            |
| Class A Ordinary Shares outstanding as of December 19, 
 2022                                                   |     | 13,269,528 (1)                                                                                                                                                                                                                                                                                                                                                                                                         |
| Use of Proceeds                                        |     | We will not receive any proceeds from the sale                                                                                                                                                                                                                                                                                                                                                                         
 of the Class A Ordinary Shares underlying the Selling Shareholder Warrants.                                                                                                                                                                                                                                                                                                                                            |
| Risk Factors                                           |     | An investment in the Class A Ordinary Shares offered under this prospectus is highly speculative and involves substantial risk. Please carefully consider the “Risk Factors” section on page 4 and other information in this prospectus for a discussion of risks. Additional risks and uncertainties not presently known to us or that we currently deem to be immaterial may also impair our business and operations |

| (1) | The number of shares of our Class A Ordinary Shares outstanding                                                                           
 prior to and that will be outstanding after this offering excludes all Warrants outstanding or issuable in connection with this offering. |

<div align='center'>3

RISK FACTORS</div>

Investing in our securities
involves a high degree of risk. You should carefully consider the risk factors set forth under “Risk Factors” described in
our most recent annual report on Form 20-F filed on April 29, 2022, as supplemented or amended and as may be updated by subsequent current
reports on Form 6-K that we have filed with the SEC, together with all other information contained or incorporated by reference in this
prospectus and any applicable prospectus supplement and in any related free writing prospectus in connection with a specific offering,
before making an investment decision. Each of the risk factors could materially and adversely affect our business, operating results,
financial condition and prospects, as well as the value of an investment in our securities