Company: EDSA
Filing Date: 2025-03-07
Form Type: CORRESP
Source: 0001171843-25-001322
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Company: Edesa Biotech, Inc.
Filing Date: 2025-03-07
Form: CORRESP
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<div align='center'>Edesa Biotech, Inc.

100 Spy Court

Markham, Ontario, Canada L3R 5H6</div>

March 7, 2025

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

| Re: | Edesa Biotech, Inc. |

Registration Statement on Form S-3 (File No. 333-285539)

Filed on March 4, 2025

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act
of 1933, as amended, Edesa Biotech, Inc. (the “”) hereby requests that the above-referenced Registration Statement
(the “”) be declared effective by the Securities and Exchange Commission at 4:05 p.m., Eastern
Time, on March 11, 2025, or as soon as practicable thereafter.

Please call Tracy Buffer of Lowenstein Sandler LLP
at (973) 597-2434 to confirm the effectiveness of the Registration Statement or with any questions.

| Very truly yours,              |
| EDESA BIOTECH, INC.            |
| By: /s/ Stephen Lemieux        |
| Name: Stephen Lemieux          |
| Title: Chief Financial Officer |