Company: HURA
Filing Date: 2025-05-23
Form Type: 424B3
Source: 0001193125-25-125499
Chunk: 986

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-05-23
Form: 424B3
Chunk 986
---
 remain in full force and effect in accordance with its terms, and all references to the Merger Agreement in this Amendment and in any ancillary agreements or documents delivered in connection with the Merger Agreement shall
hereafter refer to the Merger Agreement as amended by this Amendment, and as it may hereafter be further amended or restated.

7.
REFERENCES TO THE MERGER AGREEMENT. Once this Amendment becomes effective, each reference in the Merger Agreement to “this Agreement,” “herein,” “hereof,” “hereunder,” “hereby,”
“hereto” or words of similar import shall hereafter be deemed to refer to the Merger Agreement as amended hereby (except that references to the date of the Merger Agreement and references in the Merger Agreement to “the date
hereof,” “the date of this Agreement” or words of similar import shall continue to mean December 11, 2024).

8.
COUNTERPARTS. This Amendment may be executed in two or more counterparts, all of which shall be considered one and the same instrument and shall become effective when one or more counterparts have been signed by each of the parties and
delivered to the other party. This Amendment may be executed by.pdf signature or any electronic signature complying with the U.S. E-SIGN Act of 2000 (e.g.,www.docusign.com) and such signature shall constitute
an original for all purposes

9. INCORPORATION BY REFERENCE. Each of the provisions of Sections 8.3 (Notices), 8.8 (Governing Law),
8.9 (Consent to Jurisdiction), 8.13 (Severability) and 8.14 (Waiver of Jury Trial) of the Merger Agreement shall be incorporated by reference as if set out in full herein and shall apply hereto, mutatis mutandis.

[Signature page follows]

3

IN WITNESS WHEREOF, the parties listed below, by their duly authorized representatives, have executed this Amendment as of the date first written above.

| TUHURA BIOSCIENCES, INC.                                             |     |                         |
| By:                                                                  |     | /s/ James Bianco        |
| Name:                                                                |     | James Bianco, M.D.      |
| Title:                                                               |     | Chief Executive Officer |
| HURA MERGER SUB I, INC.                                              |     |                         |
| By:                                                                  |     | /s/ James Bianco        |
|