Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 175

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 175
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 |   |    5 | %  |
| Other income (expense)                                                   |     |                |        |   |     |      |        |   |     |        |      |   |     |   |      |    |
| Loss on change in the fair value of related party Tasly convertible debt |     |                |   (118 | ) |     |      |    (11 | ) |     |        | (107 | ) |     |   |   10 |    |
| Interest expense                                                         |     |                | (2,519 | ) |     |      | (2,161 | ) |     |        | (358 | ) |     |   |   17 | %  |
| Other income                                                             |     |                |      — |   |     |      |      6 |   |     |        |   (6 | ) |     |   | (100 | )% |
| Total other expense, net                                                 |     |                | (2,637 | ) |     |      | (2,166 | ) |     |        | (471 | ) |     |   |   22 | %  |
| Net loss                                                                 |     |              $ | (5,064 | ) |     |    $ | (4,481 | ) |     | $      | (583 | ) |     |   |   13 | %  |

Research and Development— Research
and development expenses decreased by $0.1 million, or 12%, to $0.8 million during the six months ended June 30, 2025
from $0.9 million during the six months ended June 30, 2024. The decrease was driven primarily by the decrease in CRO and
personnel costs of $0.1 million as a result of the completion of several clinical studies and a reduction of personnel while the
Company focused on closing the business combination.

General and Administrative— General
and administrative expenses increased by $0.2 million, or 14%, to $1.6 million during the six months ended June 30,
2025 from $1.4 million during the six months ended June 30, 2024. The increase was driven primarily by the increase in
accounting costs of $0.2 million as a result of increased audit and accounting fees.

Loss on Change in the Fair Value of the Tasly Convertible Loans— Loss on change in the fair value of