Company: ABBV
Filing Date: 2025-02-14
Form Type: S-3ASR
Source: 0001104659-25-014191
Chunk: 2

Company: AbbVie Inc.
Filing Date: 2025-02-14
Form: S-3ASR
Chunk 2
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 terms of the arrangements with such entities will be stated in the applicable prospectus supplement.

#### Investing in our securities involves risks. See “

#### Risk Factors
**” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 (the “2024 Annual Report”), in our subsequent periodic filings with the Securities and Exchange Commission (the “SEC”) incorporated by reference in this prospectus and in the applicable prospectus supplement or any related free writing prospectuses that we have authorized for use in connection with a specific offering.

Neither the SEC nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus. Any representation to the contrary is a criminal offense.**

<div align='center'>Prospectus dated February 14, 2025.</div>

TABLE OF CONTENTS

TABLE OF CONTENTS

| ​                                     | ​ | ​ | Page |   |    |   | ​ |
| About this Prospectus                 | ​ | ​ | ​    | ​ |  1 | ​ | ​ |
| Forward-Looking Statements            | ​ | ​ | ​    | ​ |  2 | ​ | ​ |
| Prospectus Summary                    | ​ | ​ | ​    | ​ |  3 | ​ | ​ |
| Information Incorporated by Reference | ​ | ​ | ​    | ​ |  4 | ​ | ​ |
| Where You Can Find More Information   | ​ | ​ | ​    | ​ |  5 | ​ | ​ |
| Risk Factors                          | ​ | ​ | ​    | ​ |  6 | ​ | ​ |
| Use of Proceeds                       | ​ | ​ | ​    | ​ |  7 | ​ | ​ |
| Description of Debt Securities        | ​ | ​ | ​    | ​ |  8 | ​ | ​ |
| Plan of Distribution                  | ​ | ​ | ​    | ​ | 10 | ​ | ​ |
| Legal Matters                         | ​ | ​ | ​    | ​ | 12 | ​ | ​ |
| Experts                               | ​ | ​ | ​    | ​ | 12 | ​ | ​ |

i

TABLE OF CONTENTS

### ABOUT THIS PROSPECTUS
This prospectus is part of an automatic shelf registration statement that we filed with the SEC as a “well known seasoned issuer” as defined in Rule 405 under the Securities Act of 1933, as amended (