Company: NCNA
Filing Date: 2025-05-02
Form Type: F-1/A
Source: 0001193125-25-110310
Chunk: 13

Company: NuCana plc
Filing Date: 2025-05-02
Form: F-1/A
Chunk 13
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 pursuant to such authorities.

3. As a special resolution, that, subject to the passing of
Resolution 1, the new articles of association of the Company in the form annexed to these resolutions be adopted as the articles of association of the Company in substitution for, and to the entire exclusion of, the existing articles of association
of the Company.

4. As a special resolution, that, subject to the passing of Resolution 2, the board of directors be empowered pursuant to
Section 570 of the Companies Act 2006 to allot equity securities (as defined in Section 560(1) of the Companies Act 2006) for cash under the authority given by that resolution as if Section 561(1) of the Companies Act 2006 did not apply to any such
allotment, provided that such authority shall be limited to the allotment of equity securities up to a nominal amount of £20,000,000, such authority to expire on June 30, 2026 or, if earlier, the conclusion of the annual general meeting
of the Company to be held in 2026, but prior to its expiry the Company may make offers, and enter into agreements, which would, or might, require equity securities to be allotted after the authority expires and the board of directors may allot
equity securities under any such offer or agreement as if the authority had not expired.

Offering and ADSs Issuable in the Offering

This prospectus registers up to 12,497,768 ADSs, together with Series A Warrants to purchase up to 12,497,768 ADSs and Series B Warrants to
purchase up to 12,497,768 ADSs. Each ADS, or Pre-Funded Warrant in lieu thereof, is being sold together with a Series A Warrant to purchase one ADS and a Series B Warrant to purchase one ADS. The ADSs, or Pre-Funded Warrants in lieu thereof, and the
Warrants are immediately separable and will be issued separately, but must be purchased together. The assumed combined public offering price for each ADS and accompanying Warrants is $0.5601, which was the closing price of our ADSs on The Nasdaq
Capital Market on April 28, 2025.

The Pre-Funded Warrants sold in lieu of ADSs to those purchasers, who, together with their affiliates
and certain related parties, would beneficially own more than 4.99% (or at the election of the