Company: NDRA
Filing Date: 2025-05-09
Form Type: DRS
Source: 0001654954-25-005304
Chunk: 3

Company: ENDRA Life Sciences Inc.
Filing Date: 2025-05-09
Form: DRS
Chunk 3
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 before expenses, will be $ .

Investing in our securities involves a high degree of risk. See “ Risk Factors” on page 10 of this prospectus and elsewhere in any supplements for a discussion of information that should be considered in connection with an investment in our securities.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus. Any representation to the contrary is a criminal offense.

Delivery of the securities offered hereby is expected to be made on or about , 2025, subject to satisfaction of certain customary closing conditions.

<div align='center'>The date of this prospectus is , 2025.

Sole Bookrunner</div>

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<div align='center'>CONFIDENTIAL TREATMENT REQUESTED PURSUANT TO 17 C.F.R. § 200.83

TABLE OF CONTENTS</div>

|                                                      |     | Page |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS |     |    2 |
| PROSPECTUS SUMMARY                                   |     |    4 |
| RISK FACTORS                                         |     |   11 |
| USE OF PROCEEDS                                      |     |   15 |
| CAPITALIZATION                                       |     |   16 |
| DILUTION                                             |     |   17 |
| DESCRIPTION OF OUR SECURITIES                        |     |   18 |
| UNDERWRITING                                         |     |   21 |
| LEGAL MATTERS                                        |     |   23 |
| EXPERTS                                              |     |   23 |
| WHERE YOU CAN FIND MORE INFORMATION                  |     |   23 |
| INCORPORATION BY REFERENCE                           |     |   23 |

You should rely only on the information contained in this prospectus. Neither we nor the Underwriter has authorized anyone to provide you with different information and, if provided, such information or representations must not be relied upon as having been authorized by us or the Underwriter. This prospectus shall not constitute an offer to sell or a solicitation of an offer to buy offered securities in any jurisdiction in which it is unlawful for such person to make such an offering or solicitation.

You should read this prospectus together with the additional information described below under the heading “Where You Can Find More Information.” We may also provide a prospectus supplement or post-effective amendment to the Registration Statement to add information to, or update or change information contained in, this prospect