Company: NDRA
Filing Date: 2025-10-30
Form Type: 424B5
Source: 0001213900-25-103705
Chunk: 17

Company: ENDRA Life Sciences Inc.
Filing Date: 2025-10-30
Form: 424B5
Chunk 17
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 $2.90 to a high of $11.96 and may continue to fluctuate
significantly in the future. The stock market in general and the market for healthcare companies in particular have experienced extreme
volatility that has often been unrelated to the operating performance of particular companies. As a result of this volatility, investors
may experience losses on their investment in our common stock. Additionally, we intend to use the majority of the proceeds from this offering
to purchase cryptocurrency, which has been, and will likely continue to be, volatile. When a material portion of our assets is represented
by cryptocurrency, our stock price will likely fluctuate based on the price of cryptocurrency.

Additionally, securities of certain companies
have experienced significant and extreme volatility in stock price due to a sudden increase in demand for stock resulting in aggregate
short positions in the stock exceeding the number of shares available for purchase, forcing investors with short exposure to pay a premium
to repurchase shares for delivery to share lenders. This is known as a “short squeeze.” These short squeezes have led to the
price per share of those companies to trade at a significantly inflated rate that is disconnected from the underlying value of the company.
Many investors who have purchased shares in those companies at an inflated rate face the risk of losing a significant portion of their
original investment as the price per share declines steadily as interest in those stocks abates. While we have no reason to believe our
shares would be the target of a short squeeze, there can be no assurance that they will not be in the future, and you may lose a significant
portion or all of your investment if you purchase our shares at a rate that is significantly disconnected from our underlying value.

<div align='center'>S-10</div>

Risks Related to Cryptocurrency

Absent federal regulations, there is a possibility that certain cryptocurrencies may be classified as “securities.” Any classification of a cryptocurrency as a “security” would subject us to additional regulation and could materially impact the operation of our business.

Cryptocurrency refers to digital assets that are
issued by and transmitted through an open-source protocol, collectively maintained by a peer-to-peer network of decentralized user nodes.
We believe that digital assets intrinsically linked to a blockchain system, and the value of which is derived from or is reasonably expected
to be derived from the use of the blockchain system, such as HYPE, are not securities, but neither the SEC nor any other U.S. federal
or state regulator has formally taken such a position. Despite the Trump