Company: MIRM
Filing Date: 2025-08-12
Form Type: S-3ASR
Source: 0001193125-25-178937
Chunk: 22

Company: Mirum Pharmaceuticals, Inc.
Filing Date: 2025-08-12
Form: S-3ASR
Chunk 22
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 upon which the election may be made;                                                    |

| • |     | the terms and conditions, if any, upon which we will pay amounts in addition to the stated interest, premium, if                            
 any and principal amounts of the debt securities of the series to any holder that is not a “United States person” for federal tax purposes; |

| • |     | any restrictions on transfer, sale or assignment of the debt securities of the series; and |

| • |     | any other specific terms, preferences, rights or limitations of, or restrictions on, the debt securities, any                                              
 other additions or changes in the provisions of the indenture, and any terms that may be required by us or advisable under applicable laws or regulations. |

Conversion or Exchange Rights We will set forth in the applicable prospectus supplement the terms on which a series of debt securities may be convertible into or exchangeable for our common stock or our other securities. We will include provisions as to settlement upon conversion or exchange and whether conversion or exchange is mandatory, at the option of the holder or at our option. We may include provisions pursuant to which the number of shares of our common stock or our other securities that the holders of the series of debt securities receive would be subject to adjustment. Consolidation, Merger or Sale Unless we provide otherwise in the prospectus supplement applicable to a particular series of debt securities, the indenture will not contain any covenant that restricts our ability to merge or consolidate, or sell, convey, transfer or otherwise dispose of our assets as an entirety or substantially as an entirety. However, any successor to or acquirer of such assets (other than a subsidiary of ours) must assume all of our obligations under the indenture or the debt securities, as appropriate. Events of Default under the Indenture Unless we provide otherwise in the prospectus supplement applicable to a particular series of debt securities, the following are events of default under the indenture with respect to any series of debt securities that we may issue:

| • |     | if we fail to pay any installment of interest on any series of debt securities, as and when the same shall become                                                                                                                                       
 due and payable, and such default continues for a period of 90 days; provided, however, that a valid extension of an interest payment period by us in accordance with the terms of any indenture supplemental thereto shall not constitute a default in 
 the payment of interest for this purpose;                                                                                                                                                                                                               |

| • |     | if we fail to pay the principal of, or premium