Company: PRME
Filing Date: 2025-04-22
Form Type: DEF 14A
Source: 0001628280-25-018704
Chunk: 59

Company: Prime Medicine, Inc.
Filing Date: 2025-04-22
Form: DEF 14A
Chunk 59
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 of PwC to our stockholders for ratification as a matter of good corporate practice. If the appointment is not ratified, our audit committee will consider whether it is appropriate to select another independent registered public accounting firm. Even if the appointment is ratified, our audit committee in its discretion may appoint a different registered public accounting firm at any time during the year if the audit committee determines that such a change would be in the best interests of our Company and our stockholders.

PwC served as independent registered public accounting firm for our Company with respect to the audit of the Company’s consolidated financial statements for the fiscal year ended December 31, 2024 and has been engaged by our audit committee to serve as our independent registered public accounting firm with respect to the audit of our consolidated financial statements for the fiscal year ending December 31, 2025. Representatives of PwC will be present at the Annual Meeting, will have the opportunity to make a statement if they desire to do so, and will be available to respond to appropriate questions from stockholders.

#### Principal Accountant Fees and Services
The aggregate fees billed by categories of services are as follows for each of the years ended December 31:

|                    | Fee Category |   |      2024 |     |   |    2023 |
|:-------------------|:-------------|:--|----------:|:----|:--|--------:|
| Audit Fees (1)     |              | $ | 1,092,000 |     | $ | 910,000 |
| Audit-Related Fees |              |   |         — |     |   |       — |
| Tax Fees           |              |   |         — |     |   |       — |
| All Other Fees (2) |              |   |     2,125 |     |   |     956 |
| Total Fees         |              | $ | 1,094,125 |     | $ | 910,956 |

(1) “Audit Fees” consist of fees billed for professional services performed by PwC for the audit of our annual consolidated financial statements, the review of interim consolidated financial statements, review of the registration statement on Form S-3 and Form S-8, comfort letters issued for financing, and related services that are normally provided in connection with statutory and regulatory filings or engagements.

(2) All other fees consist of database subscription fees.

Pre-Approval by Audit Committee of Principal Accountant Services

Our audit committee (or a subcommittee