Company: HURA
Filing Date: 2025-08-12
Form Type: S-1
Source: 0001193125-25-179009
Chunk: 478

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-08-12
Form: S-1
Chunk 478
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 the Act and will be governed by the final adjudication of such issue.

<div align='center'>II-6</div>

SIGNATURES Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Tampa, Florida, on this 12th day of August, 2025.

| TUHURA BIOSCIENCES, INC. |     |                         |
| By:                      |     | /s/ James A. Bianco     |
|                          |     | James A. Bianco, M.D.   |
|                          |     | Chief Executive Officer |

POWER OF ATTORNEY KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below, hereby constitutes and appoints James A. Bianco, M.D., as his or her true and lawful attorney-in-fact andagent, with full power of substitution and re-substitution, forhim or her and in his or her name, place and stead, in any and all capacities, to sign any or all amendments to this registration statement and to file the same with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact andagent full power and authority to do and perform each and every act and thing necessary or appropriate to be done with respect to this registration statement or any amendments hereto in the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorney-in-fact andagent, or his or their substitute or substitutes, may lawfully do or cause to be done by virtue thereof. Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated.

| Signature                                 
 /s/ James A. Bianco James A. Bianco, M.D. 
 /s/ Dan Dearborn Dan Dearborn             |     | Title                                                                                  
 Chief Executive Officer and Director (Principal Executive Officer)                     
 Chief Financial Officer (Principal Financial Officer and Principal Accounting Officer) |     | Date            
 August 12, 2025 
 August 12, 2025 |
|:------------------------------------------|:----|:---------------------------------------------------------------------------------------|:----|:----------------|
| /s/ James Manuso James Manuso,