Company: SNY
Filing Date: 2025-10-27
Form Type: 424B5
Source: 0001193125-25-250786
Chunk: 86

Company: Sanofi
Filing Date: 2025-10-27
Form: 424B5
Chunk 86
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, 1 Columbus Circle, 17 thFloor, MS: NYC01-1710, New York, New York 10019, Attn: Trust and Securities Services. Interest on global securities will be paid to the holder thereof by wire transfer. We may also arrange for additional payment offices, and may cancel or change these offices, including our use of the trustee’s corporate trust office, but we must maintain an office or agency in each place of payment for the debt securities of any series. These offices are called paying agents. We may also choose to act as our own paying agent. We will notify the trustee of changes in the paying agents for any particular series of debt securities. ( Section 1002) Street name and other indirect holders should consult their banks or brokers for information on how they will receive payments. Regardless of who acts as paying agent, all money that we pay to a paying agent that remains unclaimed at the end of two years after the amount is due to direct holders will be repaid to us. After that two-yearperiod, you may look only to us for payment and not to the trustee, any other paying agent or anyone else. ( Section 1003) Notices We and the trustee will send notices only to direct holders, using their addresses as listed in the trustee’s records. ( Section 106) If the notes are in global form, the holder will be DTC and we will only send notices to DTC. 13

Special Situations Mergers and Similar Events We are generally permitted to consolidate or merge with another company or entity. We are also permitted to sell or lease our assets substantially as an entirety to another corporation or other entity or to buy or lease the assets substantially as an entirety of another corporation or other entity. ( Sections 801and 802) No vote by holders of debt securities approving any of these actions is required, unless as part of the transaction we make changes to the applicable indenture requiring your approval, as described below under “— Modification and Waiver.” We may take these actions as part of a transaction involving outside third parties or as part of an internal corporate reorganization. We may take these actions even if they result in:

| • |     | a lower credit rating being assigned to the debt securities or to other of our debt; or |

| • |     | additional amounts becoming payable in respect of withholding tax. |

Except as provided below, we have no obligation under the indenture to seek to avoid these results, or any other legal or financial effects