Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119831
Chunk: 376

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 376
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 the median of the annual total compensation of all of our employees, each as required by the Investor Protection and Securities
Reform Act of 2010, which is part of the Dodd-Frank Act.

237

Director Compensation The following table provides information regarding the total compensation that was earned by or paid to each of our non-employeedirectors during the year ended December 31, 2024.

| Name(1)                        
 Current Non-Employee Directors |     | Fees Earned 
 or Paid in  
 Cash ($)    |         |     | Option        
 Awards ($)(2) |         |     | All Other        
 Compensation ($) |   |     | Total ($) |         |
|:-------------------------------|:----|:------------|--------:|:----|:--------------|--------:|:----|:-----------------|:--|:----|:----------|--------:|
| Jay Chun, M.D., Ph.D.          |     | $           |  73,125 |     | $             |  42,770 |     |                  | — |     | $         | 115,895 |
| Dorman Followwill              |     | $           | 170,545 |     | $             | 131,400 |     |                  | — |     | $         | 301,945 |
| Yue Alexander Wu, Ph.D.        |     | $           | 127,500 |     | $             |  42,770 |     |                  | — |     | $         | 170,270 |
| Annu Navani, M.D.(3)           |     | $           |       — |     | $             | 239,225 |     |                  | — |     | $         | 239,225 |
| Former Non-Employee Director   |     |             |         |     |               |         |     |                  |   |     |           |         |
| David Lemus(4)                 |     | $           | 120,000 |     | $             |  88,630 |     |                  | — |     | $         | 208,630 |

| (1) | Dr. Ji, our Executive Chairperson, and Mr. Shah, our Chief Executive Officer and President, are not                                                                                                                                
 included in this table, as each of them was our employee and therefore receives no compensation for his service as a director. Dr. Ji’s and Mr. Shah’s compensation as named