Company: SHPH
Filing Date: 2025-01-24
Form Type: 424B3
Source: 0001493152-25-003508
Chunk: 112

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-01-24
Form: 424B3
Chunk 112
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5 million.

Cash Flows from Operating Activities

|                                                 |     | Nine Months Ended 
 September 30,     |       2024 |   |     |   |       2023 |   |     |   |     Change |   |     |     |    % |    |
|:------------------------------------------------|:----|:------------------|-----------:|:--|:----|:--|-----------:|:--|:----|:--|-----------:|:--|:----|:----|-----:|:---|
| Cash used in operating activities               |     | $                 | (4,637,068 | ) |     | $ | (4,518,973 | ) |     | $ |   (118,095 | ) |     |     |    3 | %  |
| Cash provided by (used in) investing activities |     | $                 |  2,915,761 |   |     | $ | (2,916,760 | ) |     | $ |  5,832,521 |   |     |     | (200 | )% |
| Cash provided by (used in) financing activities |     | $                 |   (698,457 | ) |     | $ |  2,904,527 |   |     | $ | (3,602,984 | ) |     |     | (124 | )% |
| Cash on hand                                    |     | $                 |    156,652 |   |     | $ |  3,885,997 |   |     | $ | (3,729,345 | ) |     |     |  (96 | )% |

To date, we have not generated positive cash flows from operating activities. For the nine months ended September 30, 2024, and 2023, net cash flows used in operating activities were $4.6 million and $4.5 million, respectively, with a shift in 2024 from a majority of research and development activity costs in 2023 to additional administrative costs in 2024 associated with financing and financial reporting matters.

Cash Flows from Investing Activities

For the nine months ended September 30, 2024, we invested in trading marketable securities for $44 thousand and received $3.0 million in proceeds from disposition of marketable securities. For the nine months ended September 30, 2023, we invested in trading marketable securities for $