Company: AZN
Filing Date: 2025-09-29
Form Type: 6-K
Source: 0001104659-25-094039
Chunk: 6

Company: ASTRAZENECA PLC
Filing Date: 2025-09-29
Form: 6-K
Chunk 6
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 should not submit voting instructions in advance.

#### 5.

#### Holders of Swedish Listed Shares
Holders of Swedish Listed Shares should follow the joining instructions set out in the Notice and the separate documents sent to them. Holders of Swedish Listed Shares are encouraged to vote in advance of the General Meeting, although arrangements will be in place to facilitate voting during the General Meeting. Where holders of Swedish Listed Shares have submitted voting instructions in advance, it will not be possible to vote, or change previously submitted voting instructions, during the meeting via the online platform. Therefore, any holder of Swedish Listed Shares wishing to vote at the General Meeting should not submit voting instructions in advance.

#### 6.

#### Shareholder Helpline
If you have any questions about this document or the General Meeting, or are in any doubt as to how to complete the Form of Proxy or online proxy appointment, please contact the Company’s registrar, Equiniti, at Aspect House, Spencer Road, Lancing, West Sussex, BN99 6DA or call on +44 (0) 800 389 1580 between

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TABLE OF CONTENTS

8:30 a.m. and 5:30 p.m. (UK time), Monday to Friday (excluding English and Welsh public holidays). Calls to the helpline from outside the UK will be charged at applicable international rates. Calls may be recorded and monitored for security and training purposes. Please note that, for legal reasons, the helpline cannot provide advice on the merits of the Harmonised Listing Structure or related termination of the existing ADR Programme or give any legal, tax or financial advice.

Please note that the above helpline is not intended for use by holders of Swedish Listed Shares or AstraZeneca ADSs. Please refer to the separate documentation made available to such persons for details of the relevant arrangements.

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TABLE OF CONTENTS

PART I
LETTER FROM THE CHAIR OF A straZeneca PLC

| ​ | Directors:                                    | ​ | ​ | Registered office:                                                                             | ​ |
| ​ | Michel Demaré (Non-Executive Chair)           
 Pascal Soriot (Chief Executive Officer)       
 Aradhana Sarin (Chief Financial Officer)      
 Philip Broadley (Senior Independent Director) 
 Euan Ashley (Non-Executive Director)          
 Birgit Conix (Non-Executive Director)         
 Karen Knudsen (Non-Executive Director)        
 Rene Haas (Non-Executive Director