Company: GLPG
Filing Date: 2025-03-27
Form Type: 20-F
Source: 0001558370-25-003806
Chunk: 169

Company: GALAPAGOS NV
Filing Date: 2025-03-27
Form: 20-F
Item: Item 4
Chunk 169
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 'small molecules' and are either made synthetically or purified from plants
Black &amp; Scholes model        A mathematical description of financial markets and derivative investment instruments that is widely used in the pricing of European options and subscription rights                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
Burkitt lymphoma (BL)            BL is a rare, aggressive form of NHL that arises from B-lymphocytes, a type of white blood cells that produce antibodies. BL is the most common form of NHL in children, but it can also develop in adults. BL is more common in males than in females                                                                                                                                                                                                                                                                                                                                                                                             
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                 CAR-T                                                                                                    Chimeric antigen receptor T cells (also known as CAR-T cells) are T cells that have been genetically engineered to produce an artificial T cell receptor for use in immunotherapy                                                                                
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Cash position                              Current financial investments and cash and cash equivalents                                                                                                                                                                                                                                                                                     
CD19                                       CD19 is a protein found on the surface of B-cells, a type of white blood cell. Since CD19 is a hallmark of B-cells, the protein has been used to diagnose cancers that arise from this type of cell, notably B-cell lymphomas                                                                                                                   
Cell therapy                               Cell therapy aims to treat diseases by restoring or altering certain sets of cells or by using cells to carry a therapy through the body. With cell therapy, cells are cultivated or modified outside the body before being injected into the patient. The cells may originate from the patient (autologous cells) or a donor (allogeneic cells)
CHMP                                       Committee for Medicinal Products for Human Use is the European Medicines Agency's (EMA) committee responsible for human medicines and plays a vital role in the authorization of medicines in the European Union (EU)                                                                                                                           
Chronic Lymphocytic Leukemia (CLL)         Chronic lymphocytic leukemia is the most common leukemia in adults. It is a type of cancer that starts in cells that become certain white blood cells (called lymphocytes) in the bone marrow. The cancer (leukemia) cells originate in the bone marrow and migrate to the bloodstream                                                          
Complete Response Rate (CRR)               Term used for the absence of all detectable cancer after the treatment is completed                                                                                                                                                                                                                                                             
Compound                                   A chemical substance, often a small molecule with drug-like properties                                                                                                                                                                                                                                                                          
Contract research organization (CRO)       Organization which provides drug discovery and development services to the pharmaceutical, biotechnology and medical devices industry                                                                                                                                                                                                           
Crohn