Company: SMNR
Filing Date: 2025-07-23
Form Type: S-4/A
Source: 0001193125-25-163401
Chunk: 860

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-07-23
Form: S-4/A
Chunk 860
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 services, which will be exchanged for shares of New Semnur Common Stock upon closing of the Business Combination pursuant to the terms of the Merger Agreement.**

<div align='center'>F-98</div>

#### Annex A-1

### AGREEMENT AND PLAN OF MERGER

#### dated as of August 30, 2024

#### by and among

#### Denali Capital Acquisition Corp.,

#### Denali Merger Sub Inc.,

#### and

#### Semnur Pharmaceuticals, Inc.
TABLE OF CONTENTS

|                                                         |     |                                                                      |     | Page   |
| ARTICLE I DEFINITIONS                                   |     |                                                                      |     | A-1-2  |
| ARTICLE II DOMESTICATION                                |     |                                                                      |     | A-1-13 |
| 2.1                                                     |     | Domestication                                                        |     | A-1-13 |
| 2.2                                                     |     | Plan of Domestication                                                |     | A-1-13 |
| ARTICLE III MERGER                                      |     |                                                                      |     | A-1-13 |
| 3.1                                                     |     | Merger                                                               |     | A-1-13 |
| 3.2                                                     |     | Closing; Effective Time                                              |     | A-1-14 |
| 3.3                                                     |     | Directors and Officers                                               |     | A-1-14 |
| 3.4                                                     |     | Effect of the Merger                                                 |     | A-1-14 |
| 3.5                                                     |     | Certificate of Incorporation and Bylaws of the Surviving Corporation |     | A-1-14 |
| 3.6                                                     |     | Unit Separation                                                      |     | A-1-15 |
| 3.7                                                     |     | Section 368 Reorganization                                           |     | A-1-15 |
| 3.8                                                     |     | Withholding Rights                                                   |     | A-1-15 |
| ARTICLE IV CONSIDERATION                                |     |                                                                      |     | A-1-15 |
| 4.1                                                     |     | Conversion of Shares                                                 |     | A-1-15 |
| 4.2                                                     |     | Treatment of Company Options                                         |     | A-1-17 |
| 4.3                                                     |     | Payment of Merger Consideration                                      |     | A-1-17 |
| 4.4                                                     |     | App