Company: ERAS
Filing Date: 2025-08-12
Form Type: S-3
Source: 0001193125-25-179038
Chunk: 54

Company: Erasca, Inc.
Filing Date: 2025-08-12
Form: S-3
Chunk 54
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 31, 2024 and 2023, and for the years then ended, have been incorporated by reference herein and in the registration statement in reliance upon the report of KPMG LLP, independent
registered public accounting firm, incorporated by reference herein, and upon the authority of said firm as experts in accounting and auditing.

S-13

Up to $200,000,000

Common Stock

PROSPECTUS

Jefferies

, 2025

PART II INFORMATION NOT REQUIRED IN PROSPECTUS

| Item 14. | Other Expenses of Issuance and Distribution |

The following is an estimate of the expenses (all of which are to be paid by the registrant) that we may incur in connection with the securities being registered hereby. Each item listed is estimated, except for the SEC registration fee.

| SEC registration fee                         |     | $ | 64,825.01 | -1 |
| Printing expenses                            |     | $ |        (2 |  ) |
| Legal fees and expenses                      |     | $ |        (2 |  ) |
| Accounting fees and expenses                 |     | $ |        (2 |  ) |
| Transfer agent and trustee fees and expenses |     | $ |        (2 |  ) |
| Miscellaneous                                |     | $ |        (2 |  ) |
| Total                                        |     | $ |        (2 |  ) |

| (1) | Comprised of a registration fee of $46,829.88 for newly registered securities and a registration fee of                                                          
 $17,995.13 that was previously paid with respect to securities registered pursuant to a Registration Statement on Form S-3, as amended (File No. 333-266802) and 
 carried forward pursuant to Rule 415(a)(6) of the Securities Act of 1933, as amended.                                                                            |

| (2) | These fees are calculated based on the securities offered and the number of issuances and accordingly cannot be 
 estimated at this time.                                                                                         |

| Item 15. | Indemnification of Directors and Officers |

Section 102 of the General Corporation Law of the State of Delaware permits a corporation to eliminate the personal liability of directors of a corporation to the corporation or its stockholders for monetary damages for a breach of fiduciary duty as a director, except where the director breached his duty of loyalty, failed to act in good faith, engaged in intentional misconduct or knowingly violated a law, authorized