Company: TVRD
Filing Date: 2025-02-14
Form Type: 424B3
Source: 0001104659-25-014310
Chunk: 1181

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-02-14
Form: 424B3
Chunk 1181
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); provided, however, that each holder of record of a certificate that represented shares of pre-Reverse Split Common Stock shall receive, upon surrender of such certificate, a new certificate representing the number of whole shares of post-Reverse Split Common Stock into which the shares of pre-Reverse Split Common Stock represented by such certificate shall have been combined pursuant to the Reverse Split, as well as any cash in lieu of fractional shares of post-Reverse Split Common Stock to which such holder may be entitled as set forth above. The Reverse Split shall be effected on a record holder-by-record holder basis, such that any fractional shares of post-Reverse Split Common Stock resulting from the Reverse Split and held by a single record holder shall be aggregated.

THIRD: The foregoing amendment to the Certificate of Incorporation was duly approved by the Board.**

### FOURTH
: Thereafter, pursuant to a resolution of the Board, this Certificate of Amendment was submitted to the stockholders of the Company for their approval, and was duly adopted in accordance with the provisions of Section 242 of the DGCL.

(1)

Insert next business day after filing with the Secretary of State of the State of Delaware.

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#### FIFTH
: This amendment to the Certificate of Incorporation shall be effective on and as of as of the effective time of [5:00 p.m.], Eastern Time, on [***DATE***] (2) .

#### [SIGNATURE PAGE FOLLOWS]
(2)

Insert next business day after filing with the Secretary of State of the State of Delaware.

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#### IN WITNESS WHEREOF,
Cara Therapeutics, Inc. has caused this Certificate of Amendment to be executed by its Chief Executive Officer as of [***DATE***].

By:

Christopher Posner 
 Chief Executive Officer

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### ANNEX G

### FORM OF

### CERTIFICATE OF AMENDMENT

#### TO

### AMENDED AND RESTATED CERTIFICATE OF INCORPORATION

#### OF

#### CARA THERAPEUTICS, INC.
Cara Therapeutics, Inc. (the “

#### Company
”), a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the “

#### DGCL
**”), does hereby certify that:

FIRST: The name of this corporation