Company: BDRX
Filing Date: 2025-12-11
Form Type: F-1/A
Source: 0001214659-25-017944
Chunk: 104

Company: Biodexa Pharmaceuticals Plc
Filing Date: 2025-12-11
Form: F-1/A
Chunk 104
---
ary) in order for (a) the Depositary Shares to be registered on Form
F-6 under the Securities Act or (b) the Depositary Shares or Ordinary Shares to be traded solely in electronic book-entry form and (ii)
do not in either such case impose or increase any fees or charges to be borne by ADR holders, shall be deemed not to prejudice any substantial
rights of ADR holders or beneficial owners. Notwithstanding the foregoing, if any governmental body or regulatory body should adopt new
laws, rules or regulations that would require amendment or supplement of the Deposit Agreement or the form of ADR to ensure compliance
therewith, we and the depositary may amend or supplement the Deposit Agreement and the form of ADR (and all outstanding ADRs) at any time
in accordance with such changed laws, rules or regulations. Such amendment or supplement to the Deposit Agreement in such circumstances
may become effective before a notice of such amendment or supplement is given to ADR holders or within any other period of time as required
for compliance.

Notice of any amendment to
the Deposit Agreement or form of ADRs shall not need to describe in detail the specific amendments effectuated thereby, and failure to
describe the specific amendments in any such notice shall not render such notice invalid, provided, however, that, in each such case,
the notice given to the ADR holders identifies a means for ADR holders and beneficial owners to retrieve or receive the text of such amendment
(i.e.,upon retrieval from the SEC’s, the depositary’s or our website or upon request from the depositary).

How may the Deposit Agreement be terminated?

The depositary may at any
time, and shall at our written direction, terminate the Deposit Agreement and the ADRs by mailing notice of such termination to the registered
holders of ADRs at least thirty (30) days prior to the date fixed in such notice for such termination; provided, however, if the depositary
shall have (i) resigned as depositary under the Deposit Agreement, notice of such termination by the depositary shall not be provided
to registered ADR holders unless a successor depositary shall not be operating under the Deposit Agreement within sixty (60) days of the
date of such resignation, and (ii) been removed as depositary under the Deposit Agreement, notice of such termination by the depositary
shall not be provided to registered holders of ADRs unless a successor depositary shall not be operating under the Deposit Agreement on
the