Company: PFSA
Filing Date: 2025-08-22
Form Type: S-1/A
Source: 0001213900-25-079829
Chunk: 46

Company: Profusa, Inc.
Filing Date: 2025-08-22
Form: S-1/A
Chunk 46
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, or if our distributions from those facilities are limited or restricted in any way, we may be unable to manufacture the relevant products at the previous levels or at all. Because of the time required to approve and lease a manufacturing facility, an alternate facility and/or a third -partymay not be available on a timely basis to replace production capacity in the event manufacturing capacity is lost. We take precautions to safeguard our facilities, which include manufacturing protocols, insurance, health and safety protocols, and off -sitestorage of data. However, a natural or man -madedisaster, such as fire, flood, earthquake, act of terrorism, cyber -attackor other disruptive event, such as the COVID -19pandemic or another public health emergency, could cause substantial delays in our operations, damage, destroy or limit our manufacturing equipment, inventory, or records and cause us to incur additional expenses. Earthquakes and fires are of particular significance since our manufacturing facilities in California are located in an earthquake -pronearea. In the event our existing manufacturing facilities or equipment are affected by man -madeor natural disasters, we may be unable to manufacture products for sale or meet customer demands or sales projections. If our manufacturing operations were curtailed or ceased, it would seriously harm our business. The insurance we maintain against fires, floods, earthquakes and other natural disasters and similar events may not be adequate to cover our losses in any particular case. Further, insurance coverage may not be available or successfully secured for loss profits or business interruption relating to the COVID -19pandemic and its impacts. 26 Customer or third-party complaints or negative reviews or publicity about our company or our products could harm our reputation and brand. We expect to rely on customers who use our products to provide good reviews and word -of-mouthrecommendations to contribute to our future growth. Customers who are dissatisfied with their experiences with our products or services may post negative reviews. We may also be the subject of blog, forum or other media postings that include inaccurate statements and create negative publicity. Any negative reviews or publicity, whether real or perceived, disseminated by word -of-mouth, by the general media, by electronic or social networking means or by other methods, could harm our reputation and brand and could severely diminish consumer confidence in our products. The size and expected growth of our addressable market has not been established with precision, and may be smaller than we estimate. Our estimates of the addressable market for our current products and future products are based on a number of internal and