Company: AZN
Filing Date: 2025-06-26
Form Type: 11-K
Source: 0001683168-25-004771
Chunk: 6

Company: ASTRAZENECA PLC
Filing Date: 2025-06-26
Form: 11-K
Chunk 6
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 is $1,000 and the
maximum is two loans outstanding at any time for any eligible borrower.

| 7 |

<div align='center'>ASTRAZENECA SAVINGS AND SECURITY PLAN

Notes to Financial Statements

December 31, 2024 and 2023

_______________</div>

| 1. | Description of Plan, continued: |

Participant Loans, continued:

Loans must
generally be repaid over a period of up to five years, except for loans to purchase a principal residence which may be repaid over a period
of up to IO years. Interest rates are based on the “prime rate” published in the Wall Street Journal on the first calendar day
of the month in which the loan is taken and remains fixed over the life of the loan. The principal amount and interest on a loan shall
be repaid by level payroll deductions during each payroll period in which the loan is outstanding. As of December 31, 2024, the interest
rates on the participant loans range from 3.25% to 9.5%. The AZ Retirement Company Contributions are not available for loans.

In the case
of death, disability, termination, or retirement, a participant or, if applicable, the participant’s beneficiary, may receive a distribution
of the vested portion of his or her accounts in a lump-sum amount or in installments. In addition, a participant may elect to withdraw
all or part of his or her account in special circumstances, as defined by the Plan.

If participants
terminate employment prior to becoming fully vested in their AZ Retirement Company Contributions, then those contributions will be forfeited
and used to reduce future employer company contributions to the Plan for the remaining participants. At December 31, 2024 and 2023, forfeited
nonvested accounts totaled $46,891 and $2,649, respectively. Forfeitures used to reduce employer company contributions were $691,333 for
the year ended December 31, 2024.

| 2. | Significant Accounting 
 Policies:              |

The significant accounting policies
employed in the preparation of the accompanying financial statements are as follows:

The financial
statements of the Plan are prepared in compliance with the Department of Labor’s (“DOL”) Rules and Regulations for Reporting
and Disclosure under ERISA and under the accrual method of accounting in accordance with accounting principles generally accepted in the
United States of America (“GAAP”). Participant contributions are received by the Plan each pay period, as