Company: XXII
Filing Date: 2025-12-19
Form Type: PRE 14A
Source: 0001493152-25-028573
Chunk: 0

Company: 22nd Century Group, Inc.
Filing Date: 2025-12-19
Form: PRE 14A
Chunk 0
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<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the Securities

Exchange Act of 1934</div>

| Filed                                  
 by the Registrant ☒                    |                                                                 |
| Filed                                  
 by a Party other than the Registrant ☐ |                                                                 |
| Check                                  
 the appropriate box:                   |                                                                 |
| ☒                                      | Preliminary                                                     
 Proxy Statement                                                 |
| ☐                                      | Confidential,                                                   
 for Use of the Commission Only (as permitted by Rule 14a-6I(2)) |
| ☐                                      | Definitive                                                      
 Proxy Statement                                                 |
| ☐                                      | Definitive                                                      
 Additional Materials                                            |
| ☐                                      | Soliciting                                                      
 Material Pursuant to §240.14a-12-6I(2))                         |

<div align='center'>22nd Century Group, Inc.

(Name of Registrant as Specified in its Charter)

(Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)</div>

| Payment                                                                                              
 of Filing Fee (Check the appropriate box):                                                           |
| ☒                                                                                                    
 No fee required.                                                                                     |
| ☐                                                                                                    
 Fee paid previously with preliminary materials.                                                      |
| ☐                                                                                                    
 Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11. |

<div align='center'>321 Farmington Road, Mocksville, North Carolina 27028

Notice of Special Meeting of Stockholders and Proxy Statement</div>

TO THE HOLDERS OF COMMON STOCK:

PLEASE TAKE NOTICEthat a Special Meeting of stockholders of 22nd Century Group, Inc. (the “Company”) will be held at [ ] on Friday, February 20, 2026, beginning at 10:00 A.M, Eastern Time.

The meeting will be held for the following purposes:

| 1.. | To                                                                                                                                 
 approve an amendment to our Articles of Incorporation, as amended, to effect a reverse stock split of our outstanding common stock 
 at a ratio between 1-for-2 and 1-for-200, to be determined at the discretion of our Board of Directors (the “Reverse Split”),      
 for the purpose of complying with the Nasdaq Listing Rules, subject to the Board’s discretion to abandon such amendment (Proposal