Company: EDSA
Filing Date: 2025-03-11
Form Type: 424B3
Source: 0001171843-25-001403
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Company: Edesa Biotech, Inc.
Filing Date: 2025-03-11
Form: 424B3
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| PROSPECTUS |     | Filed Pursuant to Rule 424(b)(3) 
 Registration No. 333-285539      |

#### Edesa Biotech, Inc.
<div align='center'>7,812,496 Common Shares</div>

This prospectus relates to the resale
from time to time, by the selling shareholders identified herein (the “Selling Shareholders”) of up to (i) 3,468,746 of our
common shares, no par value (the “Shares”) and (ii) 4,343,750 of our common shares (the “Conversion Shares”) issuable
upon the conversion of our Series B-1 Convertible Preferred Shares, stated value $10,000 per share (the “Preferred Shares”).
We issued the Shares and Preferred Shares to the Selling Shareholders in a private placement that was completed on February 12, 2025 (the
“Private Placement”).

The Selling Shareholders may, from time
to time, sell, transfer or otherwise dispose of any or all of their Shares or Conversion Shares on any stock exchange, market or trading
facility on which the common shares are traded or in private transactions. These dispositions may be at fixed prices, at prevailing market
prices at the time of sale, at prices related to the prevailing market price, at varying prices determined at the time of sale, or at
negotiated prices. See “Plan of Distribution” in this prospectus for more information. We will not receive any proceeds from
the resale or other disposition of the common shares by the Selling Shareholders. See “Use of Proceeds” beginning on page
7 and “Plan of Distribution” beginning on page 12 of this prospectus for more information.

We will not receive any proceeds from
the sale or other disposition of our common shares by the Selling Shareholders. The Selling Shareholders may sell or otherwise dispose
of common shares offered by this prospectus from time to time through the means described in this prospectus under the caption “Plan
of Distribution.” We have borne and will continue to bear the costs relating to the registration of the Shares and Conversion Shares.

Our common shares are listed on the
Nasdaq Capital Market under the symbol “EDSA.” The last reported sale price for our common shares on the Nasdaq Capital Market
on March 10, 2025 was $2.31 per share.

You should read this prospectus and
any supplement, together with additional information described under the headings