Company: WHWK
Filing Date: 2025-03-28
Form Type: S-8
Source: 0001193125-25-067200
Chunk: 1

Company: Whitehawk Therapeutics, Inc.
Filing Date: 2025-03-28
Form: S-8
Chunk 1
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 Registrant”) for the purpose of registering (i) an additional 987,228 shares of common stock of the Registrant reserved for issuance pursuant to future awards under the Registrant’s Amended and Restated 2021 Equity Incentive Plan (the “ 2021 Plan”) as a result of the annual evergreen increase under the 2021 Plan, (ii) an additional 6,300,000 shares of common stock of the Registrant reserved for issuance pursuant to the 2021 Plan, which was approved by stockholders at a special meeting on February 28, 2025, and (iii) an additional 246,807 shares of common stock of the Registrant reserved for issuance under the 2021 Employee Stock Purchase Plan (the “ 2021 ESPP”) as a result of the annual evergreen increase under the 2021 ESPP. Accordingly, contents of (i) the previous Registration Statement on Form S-8filed by the Registrant with the Securities and Exchange Commission (the “ Commission”) on March 17, 2022 (File No. 333-263639)(the “ 2022 Form S-8”), (ii) the previous Registration Statement on Form S-8filed by the Registrant with the Commission on March 29, 2023 (File No. 333-270933)(the “ 2023 Form S-8”) and (iii) the previous Registration Statement on Form S-8filed by the Registrant with the Commission on February 12, 2024 (File No. 333-277020)(the “ 2024 Form S-8”, and together with the 2022 Form S-8and 2023 Form S-8,the “ Previous Forms S-8”), including the information incorporated by reference therein and the periodic reports filed after the Previous Forms S-8to maintain current information about the Registrant, are incorporated by reference into this Registration Statement pursuant to General Instruction E of Form S-8. PART I INFORMATION REQUIRED IN THE PROSPECTUS The information specified in Item 1 and Item 2 of Part I of Form S-8 isomitted from this Registration Statement in accordance with the provisions of Rule 428 under the Securities Act and the introductory note to Part I of Form S-8. Thedocuments containing the information specified in Part I of Form S-8 willbe delivered to the participants in the equity benefit plans covered by this Registration Statement as specified by Rule