Company: TVRD
Filing Date: 2025-03-24
Form Type: 425
Source: 0001104659-25-027234
Chunk: 0

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-03-24
Form: 425
Chunk 0
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<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported):
March 24, 2025

CARA THERAPEUTICS, INC.

(Exact name of registrant as specified in its charter)</div>

| Delaware                                                  |     | 001-36279               |     |         75-3175693 |
| (state or other jurisdiction of                           
 incorporation)                                            |     | -Commission File Number |     |   -I.R.S. Employer 
 Identification No. |
| 400 Atlantic Street                                       
 Suite 500                                                 
 Stamford, Connecticut                                     |     |                         |     |              06901 |
| (Address of principal executive offices)                  |     |                         |     |          -Zip Code |
| Registrant's telephone number, including area code: (203) 
 406-3700                                                  |     |                         |     |                    |

Check the appropriate box below if the Form
8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions
(seeGeneral Instruction A.2. below):

| x | Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |

| ¨ | Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |

| ¨ | Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |

| ¨ | Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |

<div align='center'>Securities registered pursuant to Section 12(b) of the Act:</div>

| Title                                    
 of each class                            |     | Trading 
 Symbol  |     | Name                         
 of each exchange             
 on which registered          |
| Common Stock, $0.001 par value per share |     | CARA    |     | The Nasdaq  Stock Market LLC |

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405