Company: AEMD
Filing Date: 2025-08-29
Form Type: CORRESP
Source: 0001683168-25-006559
Chunk: 0

Company: AETHLON MEDICAL INC
Filing Date: 2025-08-29
Form: CORRESP
Chunk 0
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<div align='center'>Aethlon Medical, Inc.
11555 Sorrento Valley Road, Suite 203

San Diego, CA 92121
(619) 941-0360</div>

August 29, 2025

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street N.E.

Washington, D.C. 20549

| Re: | Aethlon Medical, Inc.                          |
|     | Registration Statement on Form S-1, as amended |
|     | File No. 333-289745                            |
|     | REQUEST FOR ACCELERATION OF EFFECTIVENESS      |

Ladies and Gentleman:

Pursuant to Rule 461 under
the Securities Act of 1933, as amended (the “Securities Act”), Aethlon Medical, Inc., a Nevada corporation (the “Registrant”),
hereby respectfully requests that the United States Securities and Exchange Commission (the “Commission”) take appropriate
action to cause the above-referenced Registration Statement on Form S-1, as amended (File No. 333-289745), to become effective on Tuesday,
September 2, 2025, at 5:01 p.m.., Eastern Time, or as soon thereafter as is practicable.

The Registrant understands
that the Commission will consider this request as a confirmation by the Registrant that it is aware of its responsibilities under the
federal securities laws as they relate to the issuance of the securities covered by the Registration Statement.

The Registrant hereby authorizes
its counsel, Dennis Doucette, Esq. of Procopio, Cory, Hargreaves & Savitch LLP, to orally modify or withdraw this request for acceleration.
Please contact Mr. Doucette at (858) 720-6322 with any questions you may have concerning this request, and please notify him when this
request for acceleration has been granted.

| Very Truly Yours,              |                |
| Aethlon Medical, Inc.          |                |
| By:                            | /s/ Jim Frakes |
| Name: Jim Frakes               |                |
| Title: Chief Executive Officer |                |