Company: SCLXW
Filing Date: 2025-07-23
Form Type: 424B3
Source: 0001193125-25-163077
Chunk: 143

Company: Scilex Holding Co
Filing Date: 2025-07-23
Form: 424B3
Chunk 143
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 on the Principal Market nor
shall suspension by the SEC

2

or the Eligible Market have been threatened, as of the Closing Date, in writing by the SEC or the Eligible Market.

(v) The Company shall have obtained all governmental, regulatory or third-party consents and approvals, if any, necessary for
the sale of the New Tranche B Warrant, including without limitation, those required by the Principal Market, if any.

(vi)
No statute, rule, regulation, executive order, decree, ruling or injunction shall have been enacted, entered, promulgated or endorsed by any court or Governmental Entity of competent jurisdiction that prohibits the consummation of any of the
transactions contemplated hereby.

(vii) Since the date of execution of this Agreement, no event or series of events shall
have occurred that reasonably would have or result in a Material Adverse Effect (as defined below).

(viii) The Company
shall have filed a Listing of Additional Shares Notification Form with the Principal Market, if required under Nasdaq listing rules.

(ix) The transfer agent of the Company, the Holder and the Company shall have duly executed and delivered an irrevocable
transfer agent instruction letter in a form reasonably acceptable to the Holder.

(x) The Company shall have paid Kelley
Drye & Warren LLP the Legal Fee Amount in accordance with below.

(xi) The
Company shall have delivered to such Holder such other documents, instruments or certificates relating to the transactions contemplated by this Agreement as such Holder or its counsel may reasonably request.

(d) . The obligation of the Company to consummate the
Transactions is subject to the fulfillment (or waiver, at the sole option of the Company), to the Company’s reasonable satisfaction, prior to or at the Closing in question, of each of the following conditions:

(i) The representations and warranties of the Holder set forth herein shall be true and correct in all material respects as of
the date when made and as of the Closing Date as though originally made at that time (except for representations and warranties that speak as of a specific date, which shall be true and correct as of such specific date), and the Holder shall have
performed, satisfied and complied in all material respects with the covenants, agreements and conditions required by this Agreement to be performed, satisfied or complied with by the Holder at or prior to the Closing Date.

(ii) No action, proceeding, investigation, regulation or legislation shall have been instituted, threatened or proposed before
any court, governmental agency or authority or legislative body