Company: APM
Filing Date: 2025-01-03
Form Type: 424B5
Source: 0001213900-25-000606
Chunk: 28

Company: Aptorum Group Ltd
Filing Date: 2025-01-03
Form: 424B5
Chunk 28
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(as our business, financial condition, results of operations and prospects may have changed since that date), even though this prospectus,
any applicable prospectus supplement or any related free writing prospectus is delivered or securities are sold on a later date.

As permitted by SEC rules
and regulations, the registration statement of which this prospectus forms a part includes additional information not contained in this
prospectus. You may read the registration statement and the other reports we file with the SEC at its website or at its offices described
below under “Where You Can Find More Information.”

Unless the context otherwise
requires, all references in this prospectus to “Aptorum,” “we,” “us,” “our,” “the
Company” or similar words refer to Aptorum Group Limited, together with our subsidiaries.

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COMMONLY USED DEFINED TERMS</div>

| ● | “505(b)(2) Application” refers to an application for which one or more of the investigations relied upon by the applicant for approval “were not conducted by or for the applicant and for which the applicant has not obtained a right of reference or use from the person by or for whom the investigations were conducted” (21 U.S.C. 355(b)(2)).                                                                                                                                                                   |
| ● | “A*STAR” refers to Agency for Science, Technology and Research                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
| ● | “Acticule” refers to Acticule Life Sciences Limited, an 80% owned subsidiary of Aptorum Group.                                                                                                                                                                                                                                                                                                                                                                                                                         |
| ● | “Aeneas Group” refers to Aeneas Limited and its subsidiaries. Aeneas Limited is 76.8% owned by Jurchen Investment Corporation. Because Mr. Huen, a director holds 100% equity interest in Jurchen Investment Corporation, we refer Aeneas Group as a fellow subsidiary of Aptorum Group.                                                                                                                                                                                                                               |
| ● | “AGP” refers to A.G.P./Alliance Global Partners, the placement agent for the February 2020 Offering (as defined below).                                                                                                                                                                                                                                                                                                                                                                                                |
| ● | “AML” refers to Aptorum Medical Limited, a 91% owned subsidiary of Aptorum Group, as of the date of this report.                                                                                                                                                                                                                                                                                                                                                                                                       |
| ● | “AML Clinic” refers to an outpatient medical clinic operated by AML under the name of Talem Medical.                                                                                                                                                                                                                                                                                                                                                                                                                   |
| ● | “Aptorum Group” and “Group” refer to Apt