Company: RVRC
Filing Date: 2025-08-13
Form Type: S-1/A
Source: 0001213900-25-075747
Chunk: 91

Company: Revium Rx.
Filing Date: 2025-08-13
Form: S-1/A
Chunk 91
---
|:--|
| Ceftriaxone-Resistant Gonorrhea   |            | N. gonorrhea |          | $ |          55 | M |     | $ |        220 | M |     | $ |        600 |     | $ |        70 | M |
| MRSA (incl. Vancomycin-resistant) |            | S. aureus    |          | $ |         230 | M |     | $ |        690 | M |     | $ |      2,200 |     | $ |       130 | M |

We strongly believe that our novel Liposomal Nano-Mupirocin may
potentially offer a novel therapeutic approach to combat drug-resistant bacterial infections with high unmet medical need and robust
revenue potential.

References

| 1. | https://www.tropicalmedicine.ox.ac.uk/gram/news/drug-resistant-enteric-fever-has-risen-53-percent-since-1990-gram-study-estimates |

| 2. | CDC (2022). Gonorrhea Treatment                                        
 Guidelines. https://www.cdc.gov/std/treatment-guidelines/gonorrhea.htm |

| 3. | WHO (2021). Antimicrobial Resistance                                                    
 in Gonorrhea. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance |

| 4. | Red Book Online (2024). Amphotericin         
 B and AmBisome Pricing Data. IBM Micromedex. |

| 5. | GoodRx (2024). Ceftriaxone Average       
 Cost. https://www.goodrx.com/ceftriaxone |

| 6. | Drugs.com (2024). Mupirocin Ointment                 
 Pricing. https://www.drugs.com/price-guide/mupirocin |

| 7. | CDC (2022). STD Surveillance Report                              
 – Gonorrhea. https://www.cdc.gov/std/statistics/2022/default.htm |

| 8. | CDC (2020). Healthcare-Associated 
 Infections (HAI) Reports – MRSA.  |

| 9. | NIH/NIAID. Treatment Failures and 
 Resistance Trends in MRSA.        |

| 10. | Drugs.com (2024). Vancomycin Injection 
 Cost.                                  |

<div align='center'>56

Our Second Lead Candidate Nanoparticles-based Angiotensin