Company: NYXH
Filing Date: 2025-03-20
Form Type: S-8
Source: 0001104659-25-026165
Chunk: 1

Company: Nyxoah SA
Filing Date: 2025-03-20
Form: S-8
Chunk 1
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 provided pursuant to Section 7(a)(2)(B) of the Securities Act. ¨

<div align='center'>PART I.

INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>

The information specified
in Part I of Form S-8 is omitted from this Registration Statement in accordance with the provisions of Rule 428 under the
Securities Act and the introductory note to Part I of this Registration Statement. The documents containing the information specified
in Part I of Form S-8 will be delivered to the participants in the plan covered by this Registration Statement as specified
by Rule 428(b)(1) under the Securities Act.

<div align='center'>PART II

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>

Item 3. Incorporation of Documents by Reference.

The following documents filed by the Registrant
with the Commission are incorporated herein by reference:

(a) the Registrant’s Annual Report on Form 20-F for the year ended December 31, 2024, filed with the Commission on March 20, 2025;

(b) the
Registrant’s Current
Reports on Form 6-K furnished to the Commission on January 2, 2025 and March 13, 2025 (other than portions of the foregoing expressly
excluded from incorporation by reference) (No. 001-40552); and

(c) the description of the Registrant’s Ordinary Shares which is contained in the Registrant’s Registration Statement on Form 8-A (File No. 001-40552) filed with the Commission on June 28, 2021, including any amendment or report filed for the
purpose of updating such description.

All reports and other documents filed by the Registrant
after the date hereof pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act of 1934, as amended (the “Exchange
Act”), prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which
deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference herein and to be part hereof from the
date of filing of such reports and documents (the “Incorporated Documents”).

Any statement contained herein or in any Incorporated
Document shall be deemed to be modified or superseded for the purposes of this Registration Statement to the extent that a statement contained
in any subsequently filed Incorporated Document modifies or sup