Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119846
Chunk: 160

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 160
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 revenue and expenses that are not readily apparent from other sources. If our assumptions change or if actual circumstances differ from our assumptions, our operating results may be adversely affected and could fall below our publicly announced guidance or the expectations of securities analysts and investors, resulting in a decline in the market price of our Common Stock. Anti-takeover provisions in the Certificate of Incorporation and the Bylaws and under Delaware law could make an acquisition of our Company, which may be beneficial to our stockholders, more difficult and may prevent attempts by our stockholders to replace or remove our current management. The Restated Certificate of Incorporation of the Company, filed with the Secretary of State of the State of Delaware on November 10, 2022, as amended (the “Certificate of Incorporation”), the Bylaws of the Company, effective November 10, 2022 (the “Bylaws”) and the DGCL, contain provisions that could make it more difficult for a third party to acquire the Company, even if doing so might be beneficial to our stockholders. Among other things, these provisions include:

| • |     | allow our Board to authorize the issuance of undesignated preferred stock, the terms of which may be established                                                                                                         
 and the shares of which may be issued without stockholder approval, and which may include supermajority voting, special approval, dividend, or other rights or preferences superior to the rights of other stockholders; |

| • |     | provide for a classified board of directors with staggered three-year terms; |

| • |     | provide that directors may only be removed for cause, and only by the affirmative vote of holders of at least 66                          
 2/3% in voting power of all the then-outstanding shares of our capital stock entitled to vote thereon, voting together as a single class; |

| • |     | prohibit stockholder action by written consent; |

| • |     | provide that special meetings may only be called by or at the direction of the Chairperson of the Board, the 
 Board or the Chief Executive Officer;                                                                        |

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| • |     | provide that any alteration, amendment or repeal, in whole or in part, of any provision of the Bylaws by our                                                                                                               
 stockholders will require the affirmative vote of the holders of at least 66 2/3% in voting power of all the then-outstanding shares of our capital stock entitled to vote thereon, voting together as a single class; and |

| • |     |