Company: AGIO
Filing Date: 2025-04-25
Form Type: DEF 14A
Source: 0001193125-25-096719
Chunk: 6

Company: AGIOS PHARMACEUTICALS, INC.
Filing Date: 2025-04-25
Form: DEF 14A
Chunk 6
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 including the right to vote and ask questions through the virtual meeting platform. How do I virtually attend the Annual Meeting? We will host the Annual Meeting live online via webcast. In order to attend the Annual Meeting online, you must register in advance at www.proxydocs.com/AGIO prior to the deadline of June 16, 2025 at 5:00 p.m., Eastern Time. Online registration for the Annual Meeting will begin on or around April 25, 2025, and you should allow ample time for online registration. Upon completing your registration, you will receive further instructions via email, including your unique links that will allow you access to the meeting. Please be sure to follow instructions found on your Notice, proxy card and/or voting instruction form and subsequent instructions that will be delivered to you via email. The webcast of the Annual Meeting will start at 9:00 a.m., Eastern Time, on June 18, 2025. We will have technicians standing by and ready to assist you with any technical difficulties you may have accessing the virtual meeting at 9:00 a.m., Eastern Time on June 18, 2025. If you encounter any difficulties accessing the virtual meeting during registration or at the time of the virtual meeting, please contact technical support by following the instructions provided to you upon registration for the Annual Meeting. Who can vote? Only stockholders of record at the close of business on April 21, 2025, the record date for the Annual Meeting, are entitled to vote at the Annual Meeting. On this record date, there were 57,915,199 shares of our common stock outstanding. Common stock is our only class of stock outstanding. How many votes do I have? Each share of our common stock that you own as of the record date, April 21, 2025, entitles you to one vote on each matter that is voted on. Is my vote important? Your vote is important no matter how many shares you own.Please take the time to vote. Take a moment to read the instructions, choose the way to vote that is the easiest and most convenient for you and cast your vote as soon as possible. How do I vote? If you are the “record holder” of your shares, meaning that you own your shares in your own name and not through a bank, brokerage firm or other nominee, you may vote:

| (1) | Over the Internet prior to the Annual Meeting: To vote over the internet prior to the Annual Meeting, please go to