Company: SCLXW
Filing Date: 2025-11-24
Form Type: 424B3
Source: 0001193125-25-293873
Chunk: 45

Company: Scilex Holding Co
Filing Date: 2025-11-24
Form: 424B3
Chunk 45
---
 dividing [(A-B)(X)] by (A), where:

| (A) = |     | as applicable: (i) the VWAP on the Trading Day immediately preceding the date of the applicable Notice of Exercise if such                                                                                                                    
 Notice of Exercise is (1) both executed and delivered pursuant to Section 2(a) hereof on a day that is not a Trading Day or (2) both executed and delivered pursuant to Section 2(a) hereof on a Trading Day prior to the opening of “regular 
 trading hours” (as defined in Rule 600(b) of Regulation NMS promulgated under the federal securities laws) on such Trading Day, (ii) at the option of the Holder, either (y) the VWAP on the Trading Day immediately preceding the date of    
 the                                                                                                                                                                                                                                           |

4

|       |     | applicable Notice of Exercise or (z) the Bid Price of the Common Stock on the principal Trading Market as reported by                                                                                                                      
 Bloomberg as of the time of the Holder’s execution of the applicable Notice of Exercise if such Notice of Exercise is executed during “regular trading hours” on a Trading Day and is delivered within two (2) hours thereafter            
 (including until two (2) hours after the close of “regular trading hours” on a Trading Day) pursuant to Section 2(a) hereof or (iii) the VWAP on the date of the applicable Notice of Exercise if the date of such Notice of Exercise is a 
 Trading Day and such Notice of Exercise is both executed and delivered pursuant to Section 2(a) hereof after the close of “regular trading hours” on such Trading Day;                                                                     |
| (B) = |     | the Exercise Price of this Warrant, as adjusted hereunder; and                                                                                                                                                                             |
| (X) = |     | the number of Warrant Shares that would be issuable upon exercise of this Warrant in accordance with the terms of this                                                                                                                     
 Warrant if such exercise were by means of a cash exercise rather than a cashless exercise.                                                                                                                                                 |

If Warrant Shares are issued in such a cashless exercise, the parties acknowledge and agree that in accordance with Section 3(a)(9) of the Securities Act, the Warrant Shares shall take on the characteristics of the Warrants being exercised, and the holding period of the Warrant Shares being issued may be tacked onto the holding period of this Warrant. The Company agrees not to take any position contrary to this Section 2(c