Company: ARWR
Filing Date: 2025-03-07
Form Type: 424B7
Source: 0001193125-25-049889
Chunk: 26

Company: ARROWHEAD PHARMACEUTICALS, INC.
Filing Date: 2025-03-07
Form: 424B7
Chunk 26
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 of the debt securities of such series then outstanding. In addition, the holders of a majority in principal amount of the debt securities of such series then outstanding may waive any existing default under, or compliance with, any provision of the debt securities of a particular series or of the indenture relating to a particular series of debt securities, other than any event of default in payment of interest or principal. These consents and waivers may be obtained in connection with a purchase of, or tender offer or exchange offer for, debt securities. Without the consent of each holder affected, we and the trustee may not:

| • |     | reduce the amount of debt securities of such series whose holders must consent to an amendment, supplement or 
 waiver;                                                                                                       |

| • |     | reduce the rate of or extend the time for payment of interest, including defaulted interest; |

| • |     | reduce the principal of or extend the fixed maturity of any debt security or alter the provisions with respect to 
 redemptions or mandatory offers to repurchase debt securities;                                                    |

| • |     | make any change that adversely affects any right of a holder to convert or exchange any debt security into or for     
 shares of our common stock or other securities, cash or other property in accordance with the terms of such security; |

| • |     | modify the ranking or priority of the debt securities; |

| • |     | make any change to any provision of the indenture relating to the waiver of existing defaults, the rights of                                                                                                                                              
 holders to receive payment of principal and interest on the debt securities, or to the provisions regarding amending or supplementing the indenture or the debt securities of a particular series with the written consent of the holders of such series; |

| • |     | waive a continuing default or event of default in the payment of principal of or interest on the debt securities; 
 or                                                                                                                |

| • |     | make any debt security payable at a place or in money other than that stated in the debt security, or impair the 
 right of any holder of a debt security to bring suit as permitted by the indenture.                              |

The right of any holder to participate in any consent required or sought pursuant to any provision of the indenture, and our obligation to obtain any such consent otherwise required from such holder, may be subject to the requirement that such holder shall have been the holder of record of debt securities with respect to which such consent is required or sought as of a record date fixed by us in accordance with the indenture.