Company: MIRA
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001493152-25-026444
Chunk: 0

Company: MIRA PHARMACEUTICALS, INC.
Filing Date: 2025-12-05
Form: 424B5
Chunk 0
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Filed Pursuant to Rule 424(b)(5)

Registration No. 333-281467

PROSPECTUS SUPPLEMENT

(To Prospectus Supplement dated April 16, 2025 to

Prospectus Supplement dated September 26, 2024 to

Prospectus dated August 16, 2024)

<div align='center'>Up to $15,241,591

Common Stock</div>

This prospectus supplement (the “Prospectus Supplement”) amends and supplements the information in the prospectus supplement dated April 16, 2025 (the “April Prospectus”), filed as a part of our registration statement on Form S-3 (File No. 333-281467) (the “Registration Statement”) and the prospectus supplement dated September 26, 2024, contained therein (the “September Prospectus”), and the prospectus dated August 16, 2024 (the “August Prospectus” and together with the September Prospectus and April Prospectus, the “Prior Prospectus”), relating to the offering, issuance and sale by us of our common stock, par value $0.0001 per share (“Common Stock”), from time to time that may be issued and sold under the at the market offering agreement (the “Sales Agreement”), dated August 12, 2024, and amended on September 24, 2024, by and between us and Rodman & Renshaw LLC, as sales agent. This Prospectus Supplement should be read in conjunction with the Prior Prospectus, and is qualified by reference thereto, except to the extent that the information herein amends or supersedes the information contained in the Prior Prospectus. This prospectus supplement is not complete without, and may only be delivered or utilized in connection with, the Prior Prospectus and any future amendments or supplements thereto.

We are filing this Prospectus Supplement to amend the Prior Prospectus to update the maximum amount of shares we are eligible to sell under the Sales Agreement and the Prospectus Supplement. As of the date hereof, the current aggregate market value of our outstanding Common Stock held by non-affiliates, or public float, is $54,948,079, which was calculated based on 37,127,081 outstanding shares of Common Stock held by non-affiliates and a price of $1.48 per share, the last reported sales price of our Common Stock on December 4, 2025, as reported on the Nasdaq Capital Market