Company: SHPH
Filing Date: 2025-02-27
Form Type: 424B3
Source: 0001493152-25-008474
Chunk: 67

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-02-27
Form: 424B3
Chunk 67
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 provide notice that the Company’s securities will become subject to delisting. In that event, the Company will have an opportunity to appeal Nasdaq’s decision to a hearings panel.

While we aim to regain compliance with Nasdaq’s stockholders equity requirement, we nonetheless run the risk that our stock may be delisted if we fail to comply with Nasdaq listing requirements. In the event our common stock is delisted, we may seek to have our common stock quoted on an over-the-counter marketplace, such as on the OTCQX. The OTCQX is not a stock exchange, and if our common stock trades on the OTCQX rather than a securities exchange, there may be significantly less trading volume and analyst coverage of, and significantly less investor interest in, our common stock, which may lead to lower trading prices for our common stock.

Any potential delisting of our common stock from the Nasdaq may have materially adverse consequences to our stockholders, including:

| ● | a                                                                                                                                   
 reduced market price and liquidity with respect to our shares of common stock, which could make our ability to raise new investment 
 capital more difficult;                                                                                                             |
| ● | limited                                                                                                                             
 dissemination of market price of our common stock;                                                                                  |
| ● | limited                                                                                                                             
 news coverage;                                                                                                                      |
| ● | limited                                                                                                                             
 interest by investors in our common stock;                                                                                          |
| ● | volatility                                                                                                                          
 of the prices of our common stock, due to low trading volume;                                                                       |
| ● | our                                                                                                                                 
 common stock being considered a “penny stock,” which would result in broker-dealers participating in sales of our common            
 stock being subject to the regulations set forth in Rules 15g-2 through 15g-9 promulgated under the Exchange Act;                   |
| ● | increased                                                                                                                           
 difficulty in selling our common stock in certain states due to “blue sky” restrictions; and                                        |
| ● | limited                                                                                                                             
 ability to issue additional securities or to secure additional financing.                                                           |

| 50 |

Sales of substantial amounts of our securities in the public market could depress the market price of our common stock.

Our common stock is listed for trading on the Nasdaq Capital Market. If our stockholders sell substantial amounts of our common stock in the public market, or the market perceives that such sales may occur, the market price of our securities could fall and we may be unable to sell our securities in the future.

Our securities may experience extreme price and volume fluctuations, which