Company: PRME
Filing Date: 2025-11-07
Form Type: 10-Q
Source: 0001628280-25-050422
Chunk: 61

Company: Prime Medicine, Inc.
Filing Date: 2025-11-07
Form: 10-Q
Item: Part I, Item 8
Chunk 61
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 (“CODM”) to make decisions about resource allocation or performance assessment, and 3) its discrete financial information is available. The Company operates and manages its business as a single segment for the purposes of assessing performance and making operating decisions.Our chief executive officer, who is the CODM, manages and allocates resources to the operations of our company on a total company basis by assessing the overall level of resources available and how to best deploy these resources across functions and research and development projects that are in line with our long-term company-wide strategic 

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goals. In making these decisions, the CODM uses consolidated financial information for purposes of evaluating performance, forecasting future period financial results, allocating resources and setting incentive targets. The CODM performs this assessment based on the Company’s consolidated net loss. Through this analysis, the CODM assesses performance by comparing actual net loss verses the budget, and then decides how to allocate resources to invest in the Company’s research and development programs. The measure of segment assets is reported on the consolidated balance sheets as total assets.The following table contains additional information on our consolidated net loss, including significant segment expenses:Three Months Ended September 30,Nine Months Ended September 30,(in thousands)2025202420252024Total revenue$1,225 $209 $3,794 $800 Operating expenses:Research and development expensesPersonnel expenses10,898 14,935 40,146 46,140 Facility related11,353 7,735 36,087 26,371 Research costs8,379 9,714 27,531 32,723 General and administrative expenses:Personnel expenses4,370 7,433 18,608 20,273 Other segment items (1)20,198 14,624 41,164 33,538 Total operating expenses55,198 54,441 163,536 159,045 Total other income, net3,391 1,714 4,679 4,639 Net loss$(50,582)$(52,518)$(155,063)$(153,606)(1) Other segment items consist of professional and consultant fees, license and intellectual property fees, general and administrative facility costs, and settlement costs.Recently Issued Accounting Pronouncements Not Yet AdoptedIn December 2023, the FASB issued ASU 2023-09, Income Taxes (Topic 740): Improvements to Income Tax Disclosures,