Company: NCEL
Filing Date: 2025-10-24
Form Type: POS AM
Source: 0001213900-25-102149
Chunk: 0

Company: NewcelX Ltd.
Filing Date: 2025-10-24
Form: POS AM
Chunk 0
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<div align='center'>As filed with the Securities and Exchange Commission on October 24, 2025</div>

Registration No. 333-290516

<div align='center'>UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

Post-Effective Amendment No. 1

to

Form F-1

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

NLS PHARMACEUTICS LTD.

(Exact name of registrant as specified in its charter)</div>

| Switzerland                     |     |                         3841 |     | Not Applicable        |
| (State or other jurisdiction of 
 incorporation or organization)  |     | -Primary Standard Industrial 
   Classification Code Number |     | -I.R.S. Employer      
 Identification Number |

| The Circle 6                                                      |     | Puglisi & Associates                                      |
| 8058 Zurich, Switzerland                                          |     | 850 Library Ave., Suite 204, Newark, DE 19711             |
| Tel: +41.44.512.2150                                              |     | Tel: (302) 738-6680                                       |
| (Address, including zip code, and telephone number,               |     | (Name, address, including zip code, and telephone number, |
| including area code, of registrant’s principal executive offices) |     | including area code, of agent for service)                |

<div align='center'>Copies to:</div>

| Oded Har-Even, Esq.         |     | Dr. Matthias Courvoisier      |
| Howard Berkenblit, Esq.     
 Ron Ben-Bassat, Esq.        
 Sullivan & Worcester LLP    
 1251 Avenue of the Americas 
 New York, NY 10020          
 Tel: 212.660.3000           |     | Baker McKenzie Switzerland AG 
 Holbeinstrasse 30             
 Zurich, Switzerland 8034      
 Tel: +41 44 384 14 14         |

Approximate date of commencement of proposed sale to the public:As soon as practicable after the effective date hereof.

If any of the securities being registered on this
form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act, check the following box. ☒

If this form is filed to register additional securities
for an offering pursuant to Rule 462(b) under the Securities Act, check the