Company: DNLI
Filing Date: 2025-06-05
Form Type: 3
Source: 0000950170-25-082455
Chunk: 1

Company: Denali Therapeutics Inc.
Filing Date: 2025-06-05
Form: 3
Chunk 1
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 Nature of Indirect Beneficial Ownership (Instr. 5) |     |     |                |                           |     |     |   |
| $0.01 Prefunded Warrants [F5]              |                                                    $0.01 | N/A                                                                         | N/A                                                    | N/A                                                      | N/A                                                   | N/A | N/A | [F5,F6] - [F5] | Common Stock - 2,144,946  | N/A | N/A | I |
| $0.01 Prefunded Warrants [F5]              |                                                    $0.01 | N/A                                                                         | N/A                                                    | N/A                                                      | N/A                                                   | N/A | N/A | [F5,F6] - [F5] | Common Stock - 23,901,119 | N/A | N/A | I |

Remarks:

Julian C. Baker, a managing member of Baker Bros. Advisors (GP) LLC was elected as a director of Denali Therapeutics Inc. (the "Issuer") on June 3, 2025. By virtue of their representation on the board of directors of the Issuer, for purposes of Section 16 of the Securities Exchange Act of1934, as amended, the reporting persons other than Julian C. Baker are deemed directors by deputization of the Issuer.

| ** Signature of Reporting Person                                                               
 /s/ By: Baker Bros. Advisors LP, Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing | Date       
 06/05/2025 |

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