Company: ZVRA
Filing Date: 2025-04-21
Form Type: DEFC14A
Source: 0001193125-25-086293
Chunk: 1

Company: ZEVRA THERAPEUTICS, INC.
Filing Date: 2025-04-21
Form: DEFC14A
Chunk 1
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www.cesonlineservices.com/zvra25_vm by 9:00 AM Eastern Time on May 28, 2025. Please have your WHITEproxy card, voting instruction form, or other communication containing your control number available and follow the instructions to complete your registration request. Your vote will be especially important at this year’s Annual Meeting.As you may be aware, Daniel J. Mangless has nominated two nominees, Travis C. Mickle, Ph.D., and Arthur C. Regan (the “Mangless Nominees”) for election as directors at the Annual Meeting on the blue proxy card in opposition to the two Class I director nominees recommended by our Board, Wendy Dixon, Ph.D. and Tamara A. Favorito. The Board does not endorse the Mangless Nominees and recommends that you vote “FOR” the election of Wendy Dixon, Ph.D. and Tamara A. Favorito on the WHITE proxy card.The Board also recommends that you vote “ FOR” the ratification of the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm, using the WHITEproxy card. You may receive a proxy statement, blue proxy card and other solicitation materials from Mr. Mangless. Since Mr. Mangless has the option to choose which of our stockholders will receive his proxy solicitation materials, you may or may not receive them. The Company is not responsible for the accuracy of any information provided 2

by, or relating to, Mr. Mangless or his nominees contained in any proxy solicitation materials filed or disseminated by, or on behalf of, Mr. Mangless or any other statements that Mr. Mangless may otherwise make.

The Board strongly urges you to discard and not to sign or return any blue proxy card sent to you by Mr. Mangless. If you have previously submitted a blue proxy card sent to you by Mr. Mangless, you have every right to change your vote and we strongly urge you to revoke that proxy by voting for our Board’s nominees and on the other matters to be voted on at the Annual Meeting by using the enclosed WHITE proxy card. You may vote your WHITE proxy card by mail using the postage-paid return envelope enclosed or by voting via the Internet by following the instructions on your WHITE proxy card or WHITE voting instruction form. Only your latest dated proxy will be counted, and any proxy may be revoked at any time prior to its exercise at the Annual Meeting as described in the accompanying proxy statement. Even if you would like to elect one or