Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 420

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 420
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 has been prepared in accordance with Article 11 of Regulation S-X as amended by the final rule,
Release No. 33-10786 “Amendments to Financial Disclosures about Acquired and Disposed Businesses.” Release No. 33-10786
replaces the existing pro forma adjustment criteria with simplified requirements to depict the accounting for the transactions (“Transaction
Accounting Adjustments”) and present the reasonably estimable synergies and other transaction effects that have occurred or are
reasonably expected to occur (“Management’s Adjustments”). Transaction Accounting Adjustments have been presented in
separate columns, with one column representing the adjustments associated with the Offering and other columns representing the adjustments
associated with the Acquisition and related conversion of notes payable in connection with the Acquisition. The Company has elected not
to present Management’s Adjustments and will only be presenting Transaction Accounting Adjustments in the unaudited pro forma condensed
combined financial information. The unaudited pro forma condensed combined financial information does not reflect future events that may
occur after the Acquisition. The unaudited pro forma condensed combined financial information is provided for informational purposes only
and is not necessarily indicative of a true picture of the financial position and the results of operations of the combined companies
following the completion of the Acquisition. The pro forma adjustments are subject to material change and are based upon currently available
information and certain assumptions that the Company believes are reasonable.

There were no significant accounting
policy differences or other items which required adjustment in the accompanying unaudited pro forma condensed combined financial statements.

<div align='center'>UNAUDITED PRO FORMA CONDENSED COMBINED STATEMENT OF FINANCIAL POSITION
AS OF JUNE 30, 2025
(In U.S. dollars except share and per share data)</div>

|                                       |     | Aptorum 6/30/2025 |            |     | DiamiR 5/31/2025 |           |     | Offering Transaction 
 accounting           
 adjustments          |           |     | Notes  |     | Conversion of notes payable (c) |            |   |     | Acquisition Transaction 
 accounting              
 adjustments             |            |   |     | Notes |     | Pro Forma 
 Combined  |            |
|:--------------------------------------|:----|:------------------|-----------:|:----|:-----------------|----------:|:----|:---------------------|----------:|:----|:-------|:----|:--------------------------------|:-----------|:--|:----|