Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 93

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 93
---
 others who are involved in developing our products, product candidates, or other technologies. Litigation may be necessary to defend
against these and other claims challenging inventorship or our ownership of our owned patent rights, trade secrets or other intellectual
property. If we fail in defending any such claims, in addition to paying monetary damages, we may lose valuable intellectual property
rights, such as exclusive ownership of, or right to use, intellectual property that is important to our products, product candidates,
or other technologies. Even if we are successful in defending against such claims, litigation could result in substantial costs and be
a distraction to management and other employees. Any of the foregoing could have a material adverse effect on our business, financial
condition, results of operations and prospects.

Intellectual property rights do not necessarily address all potential threats.

The degree of future protection
afforded by our intellectual property rights is uncertain because intellectual property rights have limitations, and may not adequately
protect our business or permit us to maintain our competitive advantage. For example:

| ● | others may be able to make products that are similar to products and technologies we may develop or utilize       
 similar technology that are not covered by the claims of the patents that we own or license now or in the future; |

| ● | we, or our licensor(s), might not have been the first to make the inventions covered by the issued patent 
 or pending patent application that we license or may own in the future;                                   |

| ● | we, or our licensor(s), might not have been the first to file patent applications covering certain of 
 our or their inventions;                                                                              |

| ● | others may independently develop similar or alternative technologies or duplicate any of our technologies       
 without infringing, misappropriating or otherwise violating our owned or licensed intellectual property rights; |

| ● | it is possible that our pending licensed patent applications or those that we may own in the future will 
 not lead to issued patents;                                                                              |

<div align='center'>50</div>

| ● | issued patents that we own, in-license, or otherwise hold rights to may be held invalid or unenforceable 
 or have their scope narrowed, including as a result of legal challenges by our competitors;              |

| ● | our competitors might conduct research and development activities in countries where we do not have patent                                 
 rights and then use the information learned from such activities to develop competitive products for sale in our major commercial markets; |

| ● | we may not develop additional proprietary technologies that are patentable;