Company: SCLXW
Filing Date: 2025-10-07
Form Type: 424B3
Source: 0001193125-25-233522
Chunk: 4

Company: Scilex Holding Co
Filing Date: 2025-10-07
Form: 424B3
Chunk 4
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 interest subject to disclosure under Item 404(a) of Regulation S-K. There are no arrangements or understandings between Mr. Ma and any other person pursuant to which he was selected as Chief Operating Officer. The Company previously entered into its standard form of indemnification agreement with Mr. Ma in connection with his prior appointment as Chief Financial Officer. Mr. Ma’s compensation has not been changed in connection his appointment as the Company’s Chief Operating Officer.

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SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

|                       | SCILEX HOLDING COMPANY |                                     |
|                       | By:                    | /s/ Henry Ji                        |
|                       | Name:                  | Henry Ji                            |
| Date: October 7, 2025 | Title:                 | Chief Executive Officer & President |

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