Company: CL
Filing Date: 2025-04-28
Form Type: 424B2
Source: 0001104659-25-039840
Chunk: 1

Company: COLGATE PALMOLIVE CO
Filing Date: 2025-04-28
Form: 424B2
Chunk 1
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 Depository Trust Company (“DTC”) for the accounts of its participants, including Clearstream
Banking S.A. (“Clearstream”) and Euroclear Bank SA/NV (“Euroclear”) on or about ,
2025.

<div align='center'>Joint Book-Running Managers</div>

| Citigroup | Scotiabank |

<div align='center'>The date of this prospectus supplement is , 2025.

TABLE OF CONTENTS

Prospectus Supplement</div>

|                                         | Page |
| About This Prospectus Supplement        | ii   |
| Cautionary Statement on Forward-Looking 
 Statements                              | iii  |
| Summary                                 | S-1  |
| Risk Factors                            | S-4  |
| Use of Proceeds                         | S-6  |
| Description of the Notes                | S-7  |
| Material United States Federal Income   
 Tax Considerations                      | S-12 |
| Underwriting                            | S-15 |
| Where You Can Find More Information     | S-20 |
| Incorporation of Information We File    
 with the SEC                            | S-20 |
| Legal Matters                           | S-21 |
| Experts                                 | S-21 |

<div align='center'>Prospectus</div>

|                                                           | Page |
| About This Prospectus                                     |    3 |
| Cautionary Statement Regarding Forward Looking Statements |    3 |
| Colgate-Palmolive Company                                 |    4 |
| Risk Factors                                              |    5 |
| Use of Proceeds                                           |    5 |
| Description of Debt Securities                            |    5 |
| Plan of Distribution                                      |   10 |
| Where You Can Find More Information                       |   10 |
| Incorporation of Information We File With the SEC         |   11 |
| Validity of the Debt Securities                           |   11 |
| Experts                                                   |   11 |

<div align='center'>i

About this Prospectus Supplement</div>

You should rely only on the information contained or incorporated by reference in this prospectus supplement, the accompanying prospectus and any free writing prospectus we authorize to be delivered to you. We have not, and the underwriters have not, authorized anyone to provide you with additional information or information different from that contained in this prospectus supplement, the accompanying prospectus and any such free writing prospectus. We are not, and the underwriters are not, making an offer to sell these securities in any jurisdiction where the offer or sale