Company: GHRS
Filing Date: 2025-02-27
Form Type: F-3
Source: 0001140361-25-006178
Chunk: 0

Company: GH Research PLC
Filing Date: 2025-02-27
Form: F-3
Chunk 0
---
TABLE OF CONTENTS As filed with the Securities and Exchange Commission on February 27, 2025. Registration No. 333-

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 GH Research PLC (Exact name of registrant as specified in Its charter) Not Applicable (Translation of Registrant’s name into English)

| Ireland                         
 (State or other jurisdiction of 
 incorporation or organization)  |     | NOT APPLICABLE         
 (I.R.S. Employer       
 Identification Number) |

GH Research PLC Joshua Dawson House Dawson Street Dublin 2 D02 RY95 Ireland Tel: + 353 1 437 8334 (Address and telephone number of Registrant’s principal executive offices) Cogency Global Inc. 122 East 42nd Street, 18th Floor New York, NY 10168 Tel: (800) 221-0102 (Name, address, and telephone number of agent for service) Copies to :

| Deanna L. Kirkpatrick     
 Yasin Keshvargar          
 Davis Polk & Wardwell LLP 
 450 Lexington Avenue      
 New York, NY 10017        
 Tel: (212) 450-4000       |     | Alan Casey                          
 A&L Goodbody LLP                    
 3 Dublin Landings, North Wall Quay, 
 Dublin 1, D01 C4E0                  
 Ireland                             
 Tel: + 353 1 649-2000               |

Approximate date of commencement of proposed sale to the public: From time to time after the effectiveness of this registration statement. If only securities being registered on this Form are being offered pursuant to dividend or interest reinvestment plans, please check the following box.☐ If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the following box. ☒ If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.☐ If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.☐ If this Form is a