Company: SCLXW
Filing Date: 2025-02-26
Form Type: PRER14A
Source: 0001193125-25-036730
Chunk: 6

Company: Scilex Holding Co
Filing Date: 2025-02-26
Form: PRER14A
Chunk 6
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 use. Throughout this Proxy Statement, we refer to stockholders who hold their shares through a broker, bank or other nominee as “street name stockholders.” How many votes are needed for approval of each proposal?

| • |     | Proposal No. 1: The approval of the Reverse Stock Split Proposal requires that the                                                                                                                                                
 votes cast “For” the Reverse Stock Split Proposal exceed the votes cast “Against” the Reverse Stock Split Proposal. Stockholder abstentions are considered shares present and entitled to vote on this proposal, but they are not 
 counted as shares cast, and thus, will have no effect on the outcome of this proposal. Broker non-votes also will have no effect on the outcome of this proposal.                                                                 |

| • |     | Proposal No. 2: The approval of the Adjournment Proposal requires the affirmative                                                                                                                                                                     
 vote of a majority of the voting power of the issued and outstanding shares of our Common Stock and Series A Preferred Stock entitled to vote at the Special Meeting, present in person, or by remote communication, if applicable, or represented by 
 proxy. Stockholder abstentions are considered shares present and entitled to vote on this proposal, and thus, will have the same effect as a vote “Against” this proposal. Broker non-votes will have                                                 
 no effect on the outcome of this proposal.                                                                                                                                                                                                            |

What are the effects of abstentions, withheld votes and broker non-votes? An abstention represents a stockholder’s affirmative choice to decline to vote on a proposal. If a stockholder indicates on its proxy card that it wishes to abstain from voting its shares or withholds votes as to a particular proposal, or if a broker, bank or other nominee holding its customer’s shares of record causes abstentions or withheld votes to be recorded for shares, these shares will be considered present and entitled to vote at the Special Meeting. As a result, abstentions and withheld votes will be counted for purposes of determining the presence or absence of a quorum and will count as votes against Proposal No. 2; however, since abstentions and withheld votes are not counted as shares cast, they will have no impact on the outcome of Proposal No. 1. A broker non-voteoccurs when a broker, bank or other nominee holding shares for a beneficial owner does not vote on a particular proposal because the broker, bank or other nominee does not have discretionary voting power with respect to such proposal and has not received voting instructions from the beneficial owner of the shares. Broker non-voteswill