Company: HURA
Filing Date: 2025-12-10
Form Type: 424B5
Source: 0001193125-25-313799
Chunk: 3

Company: TuHURA Biosciences, Inc./NV
Filing Date: 2025-12-10
Form: 424B5
Chunk 3
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securities described in the accompanying prospectus, from time to time, in one or more offerings, in an aggregate amount not to exceed $250,000,000. Under this prospectus supplement, we are offering up to 9,462,423 shares of our Common Stock, Series
A Warrants to purchase up to 9,462,423 shares of our Common Stock, Series B Warrants to purchase up to 9,462,423 shares of our Common Stock and Placement Agent Warrants to purchase up to 283,873 shares of our Common Stock. The shares of our Common
Stock, the Warrants and the Placement Agent Warrants that may be sold under this prospectus supplement are included in the $250,000,000 of securities that may be sold under the registration statement. This prospectus supplement describes the
specific details regarding this offering, including the amount of our Common Stock, Warrants and Placement Agent Warrants being offered, the risks of investing in our Common Stock, Warrants, and Placement Agent Warrants and other items.

This document is in two parts. This prospectus supplement contains specific information about the terms of this offering, including the types,
amounts, and prices of the securities being offered and the plan of distribution. This prospectus supplement may also add, update, or change information contained in the accompanying prospectus and the documents incorporated by reference therein.
This prospectus supplement may be updated or supplemented. The accompanying prospectus gives more general information, some of which may not apply to this offering. Generally, when we refer to this “prospectus,” we are referring to both
documents combined. To the extent the information contained in this prospectus supplement differs or varies from the information contained in the accompanying prospectus or any document filed prior to the date of this prospectus supplement and
incorporated by reference, the information in this prospectus supplement will control. You should read carefully both this prospectus supplement and the accompanying prospectus, together with the additional information about us to which we refer you
in the section of this prospectus supplement entitled “Where You Can Find More Information.”

This prospectus supplement
contains summaries of certain provisions contained in some of the documents described herein, but reference is made to the actual documents for complete information. All of the summaries are qualified in their entirety by the actual documents.
Copies of some of the documents referred to herein have been filed, will be filed or will be incorporated by reference as exhibits to the registration statement of which this prospect