Company: TAK
Filing Date: 2025-10-30
Form Type: 6-K
Source: 0001395064-25-000154
Chunk: 31

Company: TAKEDA PHARMACEUTICAL CO LTD
Filing Date: 2025-10-30
Form: 6-K
Chunk 31
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 1,590,985,809 |     | Tokyo (Prime Market), Nagoya (Premier Market), Fukuoka, Sapporo, and New York |                                               | The number of shares per one unit of shares is 100 shares. |
| Total        |       |     |                1,590,985,809 |     |     |                                       1,590,985,809 |     | —                                                                             |                                               | —                                                          |

*1 The Company's American Depositary Shares (ADSs) are listed on the New York Stock Exchange.

*2 The number of shares outstanding as of the filing date does not include shares issued upon exercise of stock acquisition rights from October 1, 2025 to the filing date of Semi-annual Securities Report (October 30, 2025).

(2) Status of stock acquisition rights

1) Contents of stock option plans

Not applicable.

2) Status of other stock acquisition rights

Not applicable.

(3) Exercise status of bonds with stock acquisition rights containing a clause for exercise price adjustments

Not applicable.

(4) Changes in the total number of issued shares and the amount of share capital and capital reserve

| Date                                     |     | Change in the total number of issued shares 
 (Thousand of shares)                        |    |     | Balance of the total number of issued shares (Thousand of shares) |           |     | Change in share capital JPY (millions) |    |     | Balance of share capital 
 JPY (millions)           |           |     | Change in capital reserve JPY (millions) |    |     | Balance of capital reserve 
 JPY (millions)             |           |
| From April 1, 2025 to September 30, 2025 |     |                                             | 36 |     |                                                                   | 1,590,986 |     |                                        | 75 |     |                          | 1,694,759 |     |                                          | 75 |     |                            | 1,686,772 |

* The increase of 36 thousand shares in the total number of issued shares was due to the exercise of stock acquisition rights.

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Translation for reference purpose only

(5) Major shareholders

|                                                                                           |     |                                                                  |     | As of September 30, 2025                    |         |     |                                                                             |       |
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