Company: CERO
Filing Date: 2025-12-02
Form Type: 424B3
Source: 0001213900-25-117352
Chunk: 3

Company: CERO THERAPEUTICS HOLDINGS, INC.
Filing Date: 2025-12-02
Form: 424B3
Chunk 3
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 pursuant to the November Purchase Agreement and (iii) 12,500,000 shares of Common Stock for aggregate proceeds of approximately
$2.90 million pursuant to the July 2025 Purchase Agreement. Accordingly, in order to enable the Company to issue and sell and the Investor
to purchase from the Company, an aggregate of $25,000,000 of the Company’s outstanding shares of Common Stock, the Company and the
Investor have entered into the new Purchase Agreement described below.

On November 26, 2025, the Company entered into
a purchase agreement (the “Purchase Agreement”) with the Investor, pursuant to which the Company may issue and sell to the
Investor, from time to time as provided in the Purchase Agreement, and the Investor shall purchase from the Company up to $14,591,939
of the Company’s outstanding shares of Common Stock, subject to the satisfaction of the conditions in the Purchase Agreement. Capitalized
terms not otherwise defined shall have the meaning ascribed to them in the Purchase Agreement.

As the Purchase Agreement constitutes a continuation
of the equity line program commenced under the Prior Purchase Agreement, the Commitment Shares issued to the Investor pursuant to the
Prior Purchase Agreement shall satisfy in full the Company’s obligation to deliver any additional shares of Common Stock to the
Investor as consideration for entering into the Purchase Agreement.

At any time from and after the Commencement Date,
on any business day on which the closing sale price of the Common Stock is equal to or greater than $0.02, the Company shall have the
right, but not the obligation, to direct the Investor, by its delivery of a Fixed Purchase Notice, to purchase a Fixed Purchase Share
Amount, not to exceed the applicable Fixed Purchase Maximum Amount (calculated as of the applicable Fixed Purchase Date), at the applicable
Fixed Purchase Price therefor on the applicable Fixed Purchase Date in accordance with the Purchase Agreement; provided, however, that
the Investor’s committed obligation under any single Fixed Purchase shall not exceed the lower of 10,000 shares of Common Stock
or $100,000 (provided that all shares of Common Stock in respect of all prior Fixed Purchases, VWAP Purchases and Additional VWAP Purchases
shall have been delivered to the Investor).

In addition, at any time from and after the Commencement
Date, on any business day on which the closing sale price of the Common Stock is equal to or greater than $0.02 and such business day
is also the Purchase