Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 50

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 50
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 course of business. Any such
transactions could be favorable to such party’s shareholders.

Certain provisions of the Merger Agreement may discourage third parties from submitting alternative takeover proposals, including proposals that may be superior to the arrangements contemplated by the Merger Agreement.

The terms of the Merger Agreement
prohibit each of Aptorum and DiamiR from soliciting alternative takeover proposals or cooperating with persons making unsolicited takeover
proposals. Because the lack of a public market for DiamiR shares makes it difficult to evaluate the fairness of the Merger, the shareholders
of DiamiR may receive consideration in the Merger that is less than the fair market value of the DiamiR shares.

Aptorum and DiamiR may become involved in securities litigation or shareholder derivative litigation in connection with the Merger, and this could divert the attention of Aptorum and DiamiR management and harm the Combined Company’s business, and insurance coverage may not be sufficient to cover all related costs and damages.

Securities litigation or shareholder
derivative litigation frequently follows the announcement of certain significant business transactions, such as the sale of a business
division or announcement of a business combination transaction. Aptorum and DiamiR may become involved in this type of litigation in connection
with the Merger, and the Combined Company may become involved in this type of litigation in the future. Litigation often is expensive
and diverts management’s attention and resources, which could adversely affect the business of Aptorum, DiamiR and the Combined
Company.

If any of the events described in “Risks Related to DiamiR’s Business and Operations” occur, those events could cause the potential benefits of the Merger not to be realized.

DiamiR’s business is
expected to constitute a significant portion of the business of the Combined Company following the Merger. As a result, the risks described
below in the section entitled “Risks Related to DiamiR’s Business and Operations” beginning on page 78 are among
the most significant risks to the Combined Company if the Merger is completed. To the extent any of the events in the risks described
in the sections referenced in the previous sentence occur, those events could cause the potential benefits of the Merger not to be realized
and the market price of the Combined Company’s shares to decline.

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The pro forma financial statements are presented for illustrative purposes only and may not be an indication of the Company’s financial condition or results of operations following the completion