Company: SPRB
Filing Date: 2025-08-14
Form Type: 10-Q
Source: 0000950170-25-108888
Chunk: 8

Company: SPRUCE BIOSCIENCES, INC.
Filing Date: 2025-08-14
Form: 10-Q
Item: Item 6
Chunk 8
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ExhibitNumber
      
     Description
      
     Form
      
     File No.
      
     Exhibit
      
     Filing Date

     3.1
      
     Amended and Restated Certificate of Incorporation
      
     8-K
      
     001-39594
      
     3.1
      
     October 14, 2020

     3.2
      
     Certificate of Amendment of the Amended and Restated Certificate of Incorporation
      
     8-K
      
     001-39594
      
     3.1
      
     July 24, 2025

     3.3
      
     Amended and Restated Bylaws 
      
     8-K
      
     001-39594
      
     3.2
      
     October 14, 2020

     4.1
      
     Certificate of Designation of Preferences, Rights and Limitations of Series A Preferred Stock
      
     8-K
      
     001-39594
      
     3.1
      
     May 29, 2025

     4.2 
      
     Form of Amended 2025 Pre-Funded Warrant to Purchase Common Stock
      
     Filed herewith

     10.1
      
     Purchase Agreement, dated May 28, 2025, by and between Spruce Biosciences, Inc. and the purchaser named therein
      
     8-K 
      
     001-39594 
      
     10.1
      
     May 29, 2025 

     10.2
      
     First Amendment to Antibody License Agreement, dated July 28, 2025, by and between Spruce Biosciences, Inc. and Twist Bioscience Corporation
      
     Filed herewith

     31.1
      
     Certification of Principal Executive Officer pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as amended, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
      
     Filed herewith

     31.2
      
     Certification of Principal Financial Officer pursuant to Rules 13a-14(a) and 15d-