Company: DNLI
Filing Date: 2025-04-17
Form Type: DEF 14A
Source: 0001714899-25-000087
Chunk: 68

Company: Denali Therapeutics Inc.
Filing Date: 2025-04-17
Form: DEF 14A
Chunk 68
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04% |
| Risk-free interest rate  |     | 3.60% -4.55%            |     | 3.32% -4.80%   |     | 1.49% -4.45%   |     | 0.30% -1.45%   |     | 0.19% -1.65%   |
| Dividend yield           |     | —                       |     | —              |     | —              |     | —              |     | —              |

(3) The dollar amounts reported in this column represent the average of the amounts reported for the Company’s Non-PEO NEOs as a group (this group excludes Dr. Watts) in the “Total” column of the Summary Compensation Table in each corresponding year.

(4) The dollar amounts reported represent the average amount of “compensation actually paid” for our Non-PEO NEOs as a group (this group excludes Dr. Watts). The dollar amounts do not reflect the actual amounts of compensation paid to the non-PEO NEOs during the applicable year, but are dollar amounts derived from the starting point of the Summary Compensation Table total compensation under the methodology prescribed under SEC rules as described in (2) above and shown in the adjustment table below.

<div align='center'>-50-</div>

| Fiscal Year |     | Average Summary Compensation Table Total for non-PEO NEOs |     | Less: Average Reported Value of Equity Awards to non-PEO NEOs(a) |     | Add: Average Equity Award Adjustments to non-PEO NEOs(b) |     | Average Compensation Actually Paid to non-PEO NEOs |
| 2024        |     |                                                $4,022,759 |     | $(3,135,943)                                                     |     |                                               $2,683,543 |     |                                         $3,570,359 |
| 2023        |     |                                                $4,169,183 |     | $(3,366,890)                                                     |     |                                                 $855,306 |     |                                         $1,657,599 |
| 2022        |     |                                                $5,223,660 |     | $(4,674,277)                                                     |     |                                             $(2,650,660) |     |                                       $(2,101,277) |
| 2021        |     |                                                $6,553,764 |     | $(5,774,220