Company: ANTX
Filing Date: 2025-03-25
Form Type: S-8
Source: 0000950170-25-044432
Chunk: 4

Company: AN2 Therapeutics, Inc.
Filing Date: 2025-03-25
Form: S-8
Chunk 4
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 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Menlo Park, State of California, on March 25, 2025.

| AN2 THERAPEUTICS, INC. |     |                                       |
| By:                    |     | /s/ Eric Easom                        |
|                        |     | Eric Easom                            |
|                        |     | President and Chief Executive Officer |

### POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Eric Easom and Lucy O. Day, and each of them, as his or her true and lawful attorneys-in-fact and agents, each with the full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments to this Registration Statement (including post-effective amendments), and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them, or their or his or her substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated.

| Signature                   
 /s/ Eric Easom              |     | Title                                                                                  
 Chief Executive Officer and Board Chair                                                
 (Principal Executive Officer)                                                          |     | Date           
 March 25, 2025 |
|:----------------------------|:----|:---------------------------------------------------------------------------------------|:----|:---------------|
| Eric Easom                  |     |                                                                                        |     |                |
| /s/ Lucy O. Day             |     | Chief Financial Officer (Principal Financial Officer and Principal Accounting Officer) |     | March 25, 2025 |
| Lucy O. Day                 |     |                                                                                        |     |                |
| /s/ Joseph Zakrzewski       |     | Director                                                                               |