Company: EDSA
Filing Date: 2025-03-11
Form Type: 424B3
Source: 0001171843-25-001403
Chunk: 6

Company: Edesa Biotech, Inc.
Filing Date: 2025-03-11
Form: 424B3
Chunk 6
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 proceeds                                   |     | We will not receive any proceeds from the common shares offered by the Selling Shareholders under this prospectus.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            |
| Risk Factors                                      |     | An investment in our securities involves a high degree of risk. Before deciding whether to invest in our securities, you should consider carefully the risks and uncertainties described in the section captioned “Risk Factors” contained in our Annual Report on Form 10-K for the fiscal year ended September 30, 2024 filed with the SEC on December 13, 2024, as amended, and other filings we make with the SEC from time to time, which are incorporated by reference herein in their entirety, together with other information in this prospectus and the information incorporated by reference herein. If any of these risks actually occurs, our business, financial condition, results of operations or cash flow could suffer materially. In such event, the trading price of our common shares could decline, and you might lose all or part of your investment. |

| 4 |

### RISK FACTORS
Investing in our common shares involves
a high degree of risk. Before making an investment decision, you should review the information contained under the heading “Risk
Factors” in our most recent Annual Report on Form 10-K as such risk factors may be updated in our subsequent reports filed with
the SEC, which are incorporated by reference herein, and as may be amended, supplemented or superseded from time to time by other reports
we file with the SEC, and other information in this prospectus for a discussion of the factors you should consider before you decide to
invest in our common shares.

For a description of these reports and
information about where you can find them, see “Where You Can Find More Information” and “Incorporation of Certain Information
by Reference.” Additional risks not presently known or that we presently consider to be immaterial could subsequently materially
and adversely affect our financial condition, results of operations, business and prospects.

| 5 |

### CAUTIONARY NOTE REGARDING FORWARD-LOOKING
STATEMENTS

This prospectus and the documents incorporated herein
by reference contain “forward-looking statements” made pursuant to the safe-harbor provision of the U.S. Private Securities
Litigation Reform Act of 1995, which reflect our current expectations regarding future events. All statements other than statements of
historical facts included in or incorporated by reference into this prospectus that address activities, events or developments that we
expect, believe or