Company: NOTV
Filing Date: 2025-08-29
Form Type: S-3
Source: 0001628280-25-041413
Chunk: 60

Company: Inotiv, Inc.
Filing Date: 2025-08-29
Form: S-3
Chunk 60
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 the sale of all common shares subject to the sales agreement and (ii) the termination of the sales agreement as permitted therein. We and Jefferies may each terminate the sales agreement at any time upon ten trading days’ prior notice.

This summary of the material provisions of the sales agreement does not purport to be a complete statement of its terms and conditions. A copy of the sales agreement is filed with the SEC as an exhibit to a Current Report on Form 8-K filed under the Exchange Act and incorporated by reference in this prospectus supplement.

Jefferies and its affiliates may in the future provide various investment banking, commercial banking, financial advisory and other financial services for us and our affiliates, for which services they may in the future receive customary fees. In the course of its business, Jefferies may actively trade our securities for its own account or for the accounts of customers, and, accordingly, Jefferies may at any time hold long or short positions in such securities. In addition, an affiliate of Jefferies acts as agent and lender under our existing credit facility.

<div align='center'>S-10</div>

This prospectus supplement and the accompanying prospectus in electronic format may be made available on a website maintained by Jefferies, and Jefferies may distribute the prospectus supplement and the accompanying prospectus electronically.

<div align='center'>S-11</div>

### LEGAL MATTERS
Certain legal matters in connection with this offering will be passed upon for us by Faegre Drinker Biddle & Reath LLP. Certain legal matters in connection with this offering will be passed upon for the underwriters by Goodwin Procter LLP.

### EXPERTS
The consolidated financial statements of Inotiv, Inc. appearing in Inotiv, Inc’s Annual Report (Form 10-K) for the year ended September 30, 2024, and the effectiveness of Inotiv Inc.'s internal control over financial reporting as of September 30, 2024, have been audited by Ernst & Young LLP, independent registered public accounting firm, as set forth in their reports thereon (which contain an explanatory paragraph describing conditions that raise substantial doubt about the Company’s ability to continue as a going concern as described in Note 2 to the consolidated financial statements), which also conclude, among other things, that Inotiv, Inc. did not maintain effective internal control over financial reporting as of September 30, 2024, based on Internal Control - Integrated Framework issued by the Committee of