Company: OSIS
Filing Date: 2025-10-22
Form Type: DEF 14A
Source: 0001104659-25-101517
Chunk: 1

Company: OSI SYSTEMS INC
Filing Date: 2025-10-22
Form: DEF 14A
Chunk 1
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 by mail | ​ | ​ | Scan the QR code | ​ | ​ | Attend themeeting andcast yourballot | ​ |

Thank you for your ongoing support and continued interest in OSI Systems, Inc. By order of the Board of Directors, Victor S. Sze
Executive Vice President, General Counsel, and Secretary
October 22, 2025

TABLE OF CONTENTS Notice of Annual Meeting of Stockholders

OSI Systems is pleased to deliver proxy materials electronically via the Internet. Electronic delivery allows OSI Systems to provide you with the information you need for the annual meeting, while reducing environmental impacts and costs.

| ​ | OSI Systems is committed to making the world safer and healthier. We have a responsibility to be good stewards of the environment in which we operate. 
 We encourage OSI Systems stockholders to voluntarily elect to receive future proxy and annual report materials electronically.                         | ​ |

| ​ |     | ​ | ​ | Enroll online by following the instructions atwww.proxyvote.com                                                |   |   |     | ​ |
| ​ |     | ​ | ​ | Scan the QR code to vote using your mobile device, sign up for e-delivery or download annual meeting materials | ​ | ​ |     | ​ |

| ​ |     | ​ | ​ |     | ​ |

| ​ | ​ |        | ​ | ​ | ​ |            | ​ | ​ | ​ |         | ​ | ​ | ​ |            | ​ |
| ​ | ​ | FASTER | ​ | ​ | ​ | ECONOMICAL | ​ | ​ | ​ | CLEANER | ​ | ​ | ​ | CONVENIENT | ​ |

TABLE OF CONTENTS PROXY SUMMARY Table of Contents

| ​ |  1 | ​ | ​ | PROXY SUMMARY                                                                         | ​ |
| ​ |  1 | ​ | ​ | Meeting Agenda                                                                        | ​ |
| ​ |  2 | ​ | ​ | Environmental, Social and Governance Initiatives                                      | ​ |
| ​ |  5 | ​ | ​ | PROPOSAL 1—ELECTION OF DIRECTORS                                                      | ​ |
| ​ |  5 | ​ | ​ | Required Vote                                                                         | ​ |
| ​ |  6 | ​ | ​ | Current Directors                                                                     | ​ |
| ​ | 11 | ​ | ​ | Relationships among Directors or Executive Officers                                   | ​ |
| ​ | 11 | ​ | ​ | Director Compensation                                                                 | ​ |
| ​ | 13 | ​ | ​ |