Company: FITBI
Filing Date: 2025-11-05
Form Type: S-4
Source: 0001193125-25-267273
Chunk: 49

Company: FIFTH THIRD BANCORP
Filing Date: 2025-11-05
Form: S-4
Chunk 49
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 closing will occur on the third business day following such satisfaction or waiver, and (ii) if the date on which such conditions are satisfied or waived is less than five (5) business days prior to the first business day of the next succeeding calendar month, then the effective time shall occur on the first business day of the next calendar month. Conditions to Complete the First Merger (page 133) As more fully described in this joint proxy statement/prospectus and in the merger agreement, the completion of the first merger depends on a number of conditions being satisfied or, where legally permissible, waived. These conditions include:

| • |     | the requisite Fifth Third vote and the requisite Comerica vote having been obtained. See “The Merger                                                                                                           
 Agreement — Shareholder and Stockholder Meetings and Recommendation of Comerica’s and Fifth Third’s Boards of Directors” beginning on page 131 for additional information regarding the “requisite Fifth Third 
 vote” and the “requisite Comerica vote”;                                                                                                                                                                       |

| • |     | the authorization for listing on NASDAQ, subject to official notice of issuance, of the shares of Fifth Third              
 common stock and the depositary shares in respect of the new Fifth Third preferred stock to be issued in the first merger; |

| • |     | all requisite regulatory approvals having been obtained and remaining in full force and effect, and all statutory                                                                                                  
 waiting periods in respect thereof having expired or been terminated, without the imposition of any materially burdensome regulatory condition. See “The Mergers — Regulatory Approvals” beginning on page 116 for 
 additional information regarding the “requisite regulatory approvals” and the “materially burdensome regulatory condition”;                                                                                        |

| • |     | the effectiveness of the registration statement of which this joint proxy statement/prospectus is a part, and the 
 absence of any stop order (or proceedings for such purpose initiated or threatened and not withdrawn);            |

| • |     | no order, injunction or decree by any court or governmental entity of competent jurisdiction or other legal                                                                                             
 restraint or prohibition preventing the consummation of the mergers, the bank mergers or any of the other transactions contemplated by the merger agreement being in effect, and no law, statute, rule, |

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| regulation, order, injunction or decree having been enacted, entered, promulgated or enforced by any governmental entity which prohibits or makes illegal the consummation of the mergers, the bank 
 mergers or any of the other transactions contemplated by