Company: EDSA
Filing Date: 2025-09-09
Form Type: 424B5
Source: 0001171843-25-005799
Chunk: 5

Company: Edesa Biotech, Inc.
Filing Date: 2025-09-09
Form: 424B5
Chunk 5
---
 come into possession of this prospectus supplement or the accompanying base prospectus must
inform themselves about, and observe any restrictions relating to, the offering of the securities covered hereby and the distribution
of this prospectus supplement and the accompanying base prospectus outside the United States. This offering is not available to a resident
of Canada or a person or company in Canada. See the section entitled “Plan of Distribution” in this prospectus supplement.

This prospectus supplement and the accompanying
base prospectus contain summaries of certain provisions contained in some of the documents described herein, but reference is made to
the actual documents for complete information. All of the summaries are qualified in their entirety by the full text of the actual documents,
some of which have been filed or will be filed with the SEC and incorporated by reference herein. See “Where You Can Find More Information” in this prospectus supplement. We further note that the representations, warranties and covenants made by us in
any agreement that is filed as an exhibit to any document that is incorporated by reference into this prospectus supplement or the accompanying
base prospectus were made solely for the benefit of the parties to such agreement, including, in some cases, for the purpose of allocating
risk among the parties to such agreements, and should not be deemed to be a representation, warranty or covenant to you. Moreover, such
representations, warranties or covenants were accurate only as of the date when made. Accordingly, such representations, warranties and
covenants should not be relied on as accurately representing the current state of our affairs.

| S-1 |

This prospectus supplement and the
accompanying base prospectus contain and incorporate by reference certain market data and industry statistics and forecasts that are based
on studies sponsored by us, independent industry publications and other publicly available information. Although we believe these sources
are reliable, estimates as they relate to projections involve numerous assumptions, are subject to risks and uncertainties, and are subject
to change based on various factors, including those discussed under “Risk Factors” in this prospectus supplement and
the accompanying base prospectus and under similar headings in the documents incorporated by reference herein and therein. Accordingly,
investors should not place undue reliance on this information.

Unless otherwise noted herein, all references
to “CDN$,” “CAD$,” or “Canadian dollars” are to the currency of Canada and “$,” “dollars,”
“US$,” “United States dollars,” or “U.S. dollars” are to the currency