Company: SHPH
Filing Date: 2025-12-11
Form Type: S-1/A
Source: 0001493152-25-027310
Chunk: 9

Company: Shuttle Pharmaceuticals Holdings, Inc.
Filing Date: 2025-12-11
Form: S-1/A
Chunk 9
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 these forward-looking statements as a result of several factors including, but not
limited to, risks regarding our ability to continue as a going concern in the near term being dependent upon us successfully raising
additional equity or debt financing to fund our operations, risks regarding volatility of our stock price, risks regarding future issuance
of equity or of debt securities diluting our share capital, risks regarding our successful transition of our business from the
development, regulatory approval and commercialization of our product candidates, our ability to recognize the anticipated benefits of the Asset Purchase, expectations as to our future performance, our ability to remain listed
on the Nasdaq Capital Market, as well as those noted under “Risk Factors” in this prospectus and in the documents incorporated
by reference in this prospectus.

<div align='center'>USE OF PROCEEDS</div>

We will not receive any of the proceeds from any sale or other disposition of the shares of common stock covered by this prospectus. All proceeds from the sale of the shares will be paid directly to the selling stockholder.

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<div align='center'>SELLING STOCKHOLDER</div>

The shares of common stock being offered by the selling stockholder are those underlying the pre-funded warrant issued to the selling stockholder under the Purchase Agreement dated November 3, 2025 (see “Summary—Private Placement”). We are registering the shares of common stock in order to permit the selling stockholder to offer the shares for resale from time to time. Except for the ownership of the shares of common stock and as otherwise disclosed in this prospectus and as disclosed in this section under “Material Relationships with Selling Stockholder” below, the selling stockholder has not had any material relationship with us within the past three years. The selling stockholder is not a broker-dealer or an affiliate of a broker-dealer.

The table below lists the selling stockholder and other information regarding the beneficial ownership of the shares of common stock by the selling stockholder. The second column lists the number of shares of common stock beneficially owned by the selling stockholder, as of December 10, 2025. The third column lists the shares of common stock being offered by this prospectus by the selling stockholder.

In accordance with the terms of the Purchase Agreement, this prospectus covers the resale of the number of shares of common stock underlying a pre-funded warrant issued to the selling stockholder under the Purchase Agreement. The fourth column assumes the sale of all of the shares offered by the selling stockholder pursuant to this prospect