Company: AZN
Filing Date: 2025-07-29
Form Type: 6-K
Source: 0001104659-25-071432
Chunk: 14

Company: ASTRAZENECA PLC
Filing Date: 2025-07-29
Form: 6-K
Chunk 14
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 Profit as a percentage of Total Revenue.

EBITDA is defined as Reported Profit before tax after adding back Net finance expense, results from Joint ventures and associates and charges for Depreciation, amortisation and impairment. Reference should be made to the Reconciliation of Reported Profit before tax to EBITDA included in the Financial Performance section in this announcement.

Operating margin is defined as Operating profit as a percentage of Total Revenue.

Net debt is defined as Interest-bearing loans and borrowings and Lease liabilities, net of Cash and cash equivalents, Other investments, and Net derivative financial instruments. Reference should be made to Note 3 'Net debt', included in the Notes to the interim financial statements in this announcement.

The Company strongly encourages investors and analysts not to rely on any single financial measure, but to review AstraZeneca's financial statements, including the Notes thereto, and other available Company reports, carefully and in their entirety.

Due to rounding, the sum of a number of dollar values and percentages in this announcement may not agree to totals.

22

Financial performance Table 7: Reported Profit and Loss

| ​                                | ​ | ​       |      ​ | ​ | ​       |      ​ | ​ |        ​ | ​ |   ​ | ​ | ​ | ​       |      ​ | ​ | ​       |      ​ | ​ |        ​ | ​ |   ​ |
| ​                                | ​ | H1 2025 |        | ​ | H1 2024 |        | ​ | % Change |   |     |   |   | Q2 2025 |        | ​ | Q2 2024 |        | ​ | % Change |   |     |
| ​                                |   | $m      |        |   | $m      |        |   |   Actual |   | CER |   |   | $m      |        |   | $m      |        |   |   Actual |   | CER |
| - Product Sales                  |   | ​       | 26,670 |   | ​       | 24,629 |   |        8 |   |  10 | ​ |   | ​       | 13,795 |   | ​       | 12,452 |   |       11 |   |  10 |
| - Alliance Revenue               |   | ​       |  1,293 |   | ​       |    939 |   |       38 |   |  38 | ​