Company: TEM
Filing Date: 2025-08-08
Form Type: S-3ASR
Source: 0001193125-25-175993
Chunk: 61

Company: Tempus AI, Inc.
Filing Date: 2025-08-08
Form: S-3ASR
Chunk 61
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 Act after the filing and concurrent effectiveness of the registration statement but prior to the termination of all offerings covered by this prospectus:

You may request a copy of these filings, at no cost, by writing or telephoning us at the following address or phone number: Tempus AI, Inc. 600 West Chicago Avenue, Suite 510 Illinois, 60654 Attn: Corporate Secretary (800) 976-5448 Any statement contained in a document incorporated by reference herein shall be deemed modified or superseded to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein modifies or supersedes such statement. 12

PROSPECTUS

August 8, 2025

Prospectus Up to $500,000,000 Class A Common Stock We have entered into a Controlled Equity Offering SMSales Agreement (the “sales agreement”) with Morgan Stanley & Co. LLC (“Morgan Stanley”), Cantor Fitzgerald & Co. (“Cantor”), TD Securities (USA) LLC (“TD Securities”) and Allen & Company LLC (“Allen” and collectively, the “sales agents”) relating to the sale of shares of our Class A common stock, par value $0.0001 (the “Class A common stock”) offered by this prospectus. In accordance with the terms of the sales agreement, we may offer and sell shares of our Class A common stock from time to time through or to Morgan Stanley, Cantor, TD Securities and/or Allen acting as sales agent or principal, having an aggregate offering price of up to $500 million. Our Class A common stock is listed on the Nasdaq Global Select Market (“Nasdaq”) under the trading symbol “TEM.” On August 7, 2025, the last reported sale price of our Class A common stock was $58.74 per share. Sales of our Class A common stock, if any, under this prospectus may be made in sales deemed to be “at the market offerings” as defined in Rule 415(a)(4) promulgated under the Securities Act of 1933, as amended (the “Securities Act”), including by means of ordinary brokers’ transactions, directly on Nasdaq or to or through a market maker other than on an exchange at prevailing market prices, at prices related to prevailing market prices or at negotiated prices or by any other method permitted by law. The sales agents are not required to sell any specific number or dollar amounts of Class A common stock but will