Company: RNLXY
Filing Date: 2025-09-04
Form Type: F-6 POS
Source: 0001193805-25-001256
Chunk: 3

Company: Renalytix plc
Filing Date: 2025-09-04
Form: F-6 POS
Chunk 3
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 is a party relating to the issuance of the American Depositary 
 Shares registered hereunder or the custody of the deposited securities represented thereby. ___ None.      |

| (c) | Every material contract relating to the deposited securities between the Depositary and the issuer of 
 the deposited securities in effect at any time within the last three years. ___ None.                 |

| (d) | Opinion of counsel for the Depositary as to the legality of the securities to be registered. ___                                        
 Previously filed as Exhibit (d) to the Registration Statement on Form F-6, Reg. No. 333-239729, filed on July 7, 2020, and incorporated 
 herein by reference.                                                                                                                    |

| (e) | Certificate under Rule 466. ___ None. |

| (f) | Powers of Attorney for certain officers and directors and the authorized representative of the Company. 
 ___ Set forth on the signature pages hereto.                                                            |

<div align='center'>II-1</div>

| Item 6. | UNDERTAKINGS |

| (b) | The Depositary undertakes to make available at the principal office of the Depositary in the United States,                                 
 for inspection by holders of ADSs, any reports and communications received from the issuer of the deposited securities which are both       
 (1) received by the Depositary as the holder of the deposited securities, and (2) made generally available to the holders of the underlying 
 securities by the issuer.                                                                                                                   |

| (c) | If the amount of fees charged is not disclosed in the prospectus, the Depositary undertakes to prepare                                 
 a separate document stating the amount of any fee charged and describing the service for which it is charged and to deliver promptly a 
 copy of such fee schedule without charge to anyone upon request. The Depositary undertakes to notify each registered holder of an ADS  
 thirty (30) days before any change in the fee schedule.                                                                                |

<div align='center'>II-2</div>

Pursuant to the requirements
of the Securities Act of 1933, as amended, Citibank, N.A., acting solely on behalf of the legal entity created by the Deposit Agreement,
as amended, by and among Renalytix plc, Citibank, N.A., as depositary, and all Holders and Beneficial Owners from time to time of American
Depositary Shares to be issued thereunder, certifies that it has reasonable grounds to believe that all the requirements