Company: RVRC
Filing Date: 2025-08-13
Form Type: S-1/A
Source: 0001213900-25-075747
Chunk: 35

Company: Revium Rx.
Filing Date: 2025-08-13
Form: S-1/A
Chunk 35
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 Iran which began on June 13 until a ceasefire was declared
on June 25, 2025. Such potential disruption to our operations may include certain delays and diversions of the import of certain components
for manufacturing and production as a result of reduced air travel and the attacks on container ships on the Red Sea route by the Iranian-backed
Houthi Movement.

In
April 2024 and October 2024, Iran launched direct attacks on Israel involving hundreds of drones and missiles and has threatened to continue
to attack Israel. On June 13, 2025, in light of continued nuclear threats and intelligence assessments indicating imminent attacks, Israel
launched a pre-emptive strike directly targeting military and nuclear infrastructure inside Iran aimed to disrupt Iran’s capacity
to coordinate or launch further hostilities against Israel, as well as disrupt its nuclear program. On June 25, 2025, a ceasefire between
Israel and Iran took effect. Nonetheless, hostilities between Israel and Iran may resume and further escalate, with both sides launching
attacks against one another. In addition, as of June 13, 2025 till the ceasefire with Iran, Israel has temporarily closed its airspace
and ceased all port activity related to commercial shipments. As a result, certain shipments and deliveries of certain components for
manufacturing and production may be significantly delayed or diverted and, therefore, may result in supply limitations and in delayed
shipments to customers.

The
intensity and duration of the multi-front conflict are difficult to predict, as are such conflict’s economic implications on our
business and operations and on Israel’s economy in general. The potential deterioration of Israel’s economy, as a direct
and indirect result of these events, may have a material adverse effect on the Company and its ability to effectively conduct its operations.

Prior
to October 2023, the Israeli government pursued extensive changes to Israel’s judicial system. In response to the foregoing developments,
individuals, organizations and institutions, both within and outside of Israel, have voiced concerns that the proposed changes may negatively
impact the business environment in Israel including due to reluctance of foreign investors to invest or transact business in Israel as
well as to increased currency fluctuations, downgrades in credit rating, increased interest rates, increased volatility in securities
markets, and other changes in macroeconomic conditions. To the extent that any of these negative developments do occur, they may have
an adverse effect on our business, our results of operations and our ability to raise additional funds, if deemed necessary by our