Company: EPR-PE
Filing Date: 2025-11-05
Form Type: 424B5
Source: 0001193125-25-266433
Chunk: 169

Company: EPR PROPERTIES
Filing Date: 2025-11-05
Form: 424B5
Chunk 169
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 units, as applicable, in various private transactions. Such selling security holders may be parties to a registration rights agreement with us, or we otherwise may have agreed
or will agree to register their securities for resale. The initial purchasers of our securities, as well as their transferees, pledgees, donees or successors, all of whom we refer to as “selling security holders,” may from time to time
offer and sell the securities pursuant to this prospectus and any applicable prospectus supplement.

The selling security holders may
offer for sale all or some portion of the securities that they hold. To the extent that any of the selling security holders are brokers or dealers, they are deemed to be, under interpretations of the SEC, “underwriters” within the
meaning of the Securities Act.

The applicable prospectus supplement will set forth the name of each of the selling security holders and
the number and classes of our securities beneficially owned by such selling security holders that are covered by such prospectus supplement. The applicable prospectus supplement will also disclose whether any of the selling security holders has held
any position or office with, has been employed by or otherwise has had a material relationship with us during the three years prior to the date of the prospectus supplement.

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PLAN OF DISTRIBUTION We and the selling security holders may sell common shares, preferred shares, depositary shares, warrants, debt securities and units:

| • |     | to or through underwriters or dealers or an underwriting syndicate represented by one or more managing 
 underwriters;                                                                                          |

| • |     | to or through agents; |

| • |     | directly to one or more purchasers, including our affiliates; |

| • |     | in block trades; |

| • |     | if indicated in the prospectus supplement, pursuant to delayed delivery contracts; or |

| • |     | through any combination of these methods. |

The distribution of common shares, preferred shares, depositary shares, warrants, debt securities and units may be effected from time to time in one or more transactions either:

| • |     | at a fixed price or prices which may be changed; |

| • |     | at market prices prevailing at the time of sale; |

| • |     | at prices relating to those market prices; or |

| • |     | at negotiated prices. |

For each offering of common shares, preferred shares, depositary shares, warrants, debt securities or units, the prospectus supplement or other offering materials will describe:

|