Company: NDRA
Filing Date: 2025-11-26
Form Type: 424B4
Source: 0001213900-25-115097
Chunk: 1

Company: ENDRA Life Sciences Inc.
Filing Date: 2025-11-26
Form: 424B4
Chunk 1
---
Plan of Distribution.”

We will bear all costs, expenses
and fees in connection with the registration of the Shares. The selling stockholders will bear all commissions and discounts, if any,
attributable to their respective sales of the Shares. For more information about the selling stockholders, please see the section entitled
“Selling Stockholders.”

We will not receive any proceeds
from the sale of Shares by the selling stockholders. We will, however, receive the proceeds from any cash exercises of Warrants.

Our common stock is listed on The Nasdaq Capital Market (“Nasdaq”)
under the symbol “NDRA”. On November 25, 2025, the last reported sale price of our common stock on Nasdaq was $5.42 per share.

Investing in our common stock involves a high degree of risk. Please read the information contained in and incorporated by reference under the heading “Risk Factors” beginning on page 5 of this prospectus and the risk factors described in the documents that are incorporated by reference into this prospectus, as they may be amended, updated or modified periodically in our reports filed with the Securities and Exchange Commission.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus or the accompanying prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

<div align='center'>The date of this prospectus is November 26, 2025

TABLE OF CONTENTS</div>

|                                                      | Page |
| ABOUT THIS PROSPECTUS                                |   ii |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS |  iii |
| PROSPECTUS SUMMARY                                   |    1 |
| RISK FACTORS                                         |    5 |
| USE OF PROCEEDS                                      |   14 |
| DESCRIPTION OF CAPITAL STOCK                         |   14 |
| SELLING STOCKHOLDERS                                 |   17 |
| DIVIDEND POLICY                                      |   19 |
| PLAN OF DISTRIBUTION                                 |   19 |
| LEGAL MATTERS                                        |   21 |
| EXPERTS                                              |   21 |
| WHERE YOU CAN FIND MORE INFORMATION                  |   21 |
| INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE      |   21 |

We have not, nor has any selling stockholder, authorized any dealer, salesperson or other person to give any information or to make any representation other than those contained in or incorporated by