Company: SCLXW
Filing Date: 2025-05-14
Form Type: 424B3
Source: 0001193125-25-119846
Chunk: 193

Company: Scilex Holding Co
Filing Date: 2025-05-14
Form: 424B3
Chunk 193
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 of
$50.0 million, of which the principal amount of $38.0 million remained outstanding as of December 31, 2024.

Interest Expense, Net

Interest expense, net for the years ended December 31, 2024 and 2023 was $2.0 million and $1.1 million,
respectively. The increase was attributed to $0.8 million of interest related to the Revolving Facility and $0.1 million of interest related to deferred consideration for GLOPERBA license acquired from Romeg in 2022.

Liquidity and Capital Resources

As of
December 31, 2024, we had cash and cash equivalents of approximately $3.3 million.

We have funded our operations primarily
through the Yorkville financing pursuant to the A&R Yorkville Purchase Agreement (as defined below), the B. Riley Principal Capital II, LLC (“B. Riley”) financing pursuant to the B. Riley Purchase Agreement (as defined below), the
Revolving Facility, the issuance of the Convertible Debentures and financing pursuant to the ATM Sales Agreement. We also have indebtedness pursuant to the Oramed Note and Tranche B Notes as well as deferred consideration related to the GLOPERBA
license acquired

122

from Romeg in 2022. The following table summarizes the aggregate indebtedness of these issuances as of December 31, 2024 and December 31, 2023 (in thousands):

| Oramed Note (outstanding principal balance: $25.0 million and $100.9 million as of       
 December 31, 2024 and 2023, respectively)                                                |     | December 31, 
 2024         | 12,161 |     | December 31, 
 2023         | 104,089 |
|:-----------------------------------------------------------------------------------------|:----|:-------------|-------:|:----|:-------------|--------:|
| Convertible Debentures (outstanding principal balance: nil and $4.4 million as of        
 December 31, 2024 and 2023, respectively)                                                |     |              |      — |     |              |   4,340 |
| Tranche B Notes (outstanding principal balance: $38.0 million and nil as of December 31, 
 2024 and 2023, respectively)                                                             |     |              | 23,560 |     |              |       — |
| Purchased