Company: ZVRA
Filing Date: 2025-04-07
Form Type: DEFA14A
Source: 0001193125-25-074700
Chunk: 1

Company: ZEVRA THERAPEUTICS, INC.
Filing Date: 2025-04-07
Form: DEFA14A
Chunk 1
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 Zevra content posted by the corporate social media account. |

| • |     | Like/react (any content). |

| • |     | Reshare without commentary (any content). |

| • |     | Feel free to comment on posts that do not mention NPC/MIPLYFFA, UCD/OLPRUVA in order to: |

| • |     | Express excitement about a corporate accomplishment, upcoming/recently completed event. |

| • |     | Celebrate a fellow team member or holiday. |

| • |     | Do Not: |

| • |     | Discuss branded products. |

| • |     | Share medical, clinical, commercial, or financial claims around Zevra’s products, services, or plans. |

| • |     | Discuss or comment on the proxy contest, proxy statement, annual meeting, nominees for election, or stockholder 
 vote.                                                                                                           |

Thank you for your commitment to Zevra and the patients we serve. Sincerely, Corporate Communications

Additional Information and Where to Find It

Zevra intends to file with the SEC a definitive proxy statement on Schedule 14A, containing a form of WHITE proxy card, with respect to its solicitation
of proxies for the 2025 Annual Meeting of Stockholders.

INVESTORS AND SECURITY HOLDERS ARE URGED TO READ CAREFULLY AND IN THEIR ENTIRETY THE PROXY
STATEMENT (INCLUDING ANY AMENDMENTS OR SUPPLEMENTS THERETO) THAT WILL BE FILED BY ZEVRA, AND ANY OTHER RELEVANT DOCUMENTS TO BE FILED BY ZEVRA WITH THE SEC WHEN THEY BECOME AVAILABLE, BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION ABOUT ANY
SOLICITATION.

Investors and security holders may obtain copies of these documents and other documents filed with the SEC by Zevra free of charge through
the website maintained by the SEC at www.sec.gov. Copies of the documents filed by Zevra are also available free of charge by accessing Zevra’s investor relations website at .

Participants in the Solicitation

Zevra, its directors,
executive officers, and employees may be deemed to be participants in the solicitation of proxies with respect to a solicitation by Zevra. Information about Zevra’s executive officers and directors is available under the heading
“Information about our Executive Officers and Directors” in Part I of Zevra’s Annual Report on Form 10-K for the year ended December 31,