Company: SXTPW
Filing Date: 2025-09-05
Form Type: 424B5
Source: 0001213900-25-085050
Chunk: 43

Company: 60 DEGREES PHARMACEUTICALS, INC.
Filing Date: 2025-09-05
Form: 424B5
Chunk 43
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 Market under the symbol “SXTP.” The last reported sale price of our common stock on The Nasdaq Capital
Market on September 3, 2025, was $1.46 per share.

The transfer agent for our
common stock is Equity Stock Transfer, LLC (“Equity Stock Transfer”), located at 237 West 37th Street, Suite 602, New York,
NY 10018. The phone number and facsimile number for Equity Stock Transfer are (212) 575-5757 and (347) 584-3644, respectively. Additional
information about Equity Stock Transfer can be found on its website at www.equitystock.com.

<div align='center'>S-25

LEGAL MATTERS</div>

The validity of the securities being offered in this offering will
be passed upon for us by Sichenzia Ross Ference Carmel LLP, New York, NY. Certain legal matters in connection with this offering will
be passed upon for the Agent by Troutman Pepper Locke LLP, Charlotte, North Carolina.

<div align='center'>EXPERTS</div>

RBSM LLP, an independent registered
public accounting firm, audited our financial statements for the years ended December 31, 2024, and 2023, respectively. We have included
our financial statements in this prospectus by reference in reliance on the reports of RBSM LLP, given
their authority as experts in accounting and auditing.

<div align='center'>WHERE YOU CAN FIND MORE INFORMATION</div>

This prospectus supplement
and the accompanying prospectus form part of a registration statement on Form S-3 that we filed with the SEC. This prospectus supplement
and the accompanying prospectus do not contain all of the information set forth in the registration statement and the exhibits to the
registration statement or the documents incorporated by reference herein and therein. For further information with respect to us and the
securities that we are offering under this prospectus supplement, we refer you to the registration statement and the exhibits and schedules
filed as a part of the registration statement and the documents incorporated by reference herein and therein. You should rely only on
the information contained in this prospectus supplement or the accompanying prospectus or incorporated by reference herein or therein.
We have not authorized anyone else to provide you with different information. We are not making an offer of these securities in any state
where the offer is not permitted. You should not assume that the information in this prospectus supplement is accurate as of any date