Company: TVRD
Filing Date: 2025-02-14
Form Type: 424B3
Source: 0001104659-25-014310
Chunk: 693

Company: Tvardi Therapeutics, Inc.
Filing Date: 2025-02-14
Form: 424B3
Chunk 693
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 any affirmative vote of the holders of any particular class or series of stock of Cara required by law or by Cara’s amended and restated certificate of incorporation or any certificate of designation filed with respect to a series of preferred stock, the affirmative vote of the holders of at least 66 2 ∕ 3 % of the voting power of all of the then outstanding shares of common stock of Cara entitled to vote generally in the election of directors, voting together as a single class, shall be required to alter, amend or repeal Articles V, VI, VII and VIII of Cara’s amended and restated certificate of incorporation.

#### Amendment of Bylaws

#### Tvardi
Under Tvardi’s amended and restated certificate of incorporation and bylaws, the Tvardi Board is expressly authorized to make, repeal, alter, amend and rescind any or all of Tvardi’s bylaws, subject to the protective provisions described above. Tvardi’s bylaws further provide that the bylaws may be adopted, amended or repealed by the vote of the holders of the majority of the stock entitled to vote at a meeting.

#### Cara
Cara’s amended and restated certificate of incorporation and amended and restated bylaws provide that the Cara Board is expressly empowered to adopt, amend or repeal Cara’s amended and restated bylaws. Any adoption, amendment or repeal of the Cara amended and restated bylaws by the Cara Board shall require the approval of a majority of the authorized number of directors. Cara’s amended and restated certificate of incorporation also provides that the Cara stockholders shall also have power to adopt, amend or repeal Cara’s amended and restated bylaws; provided , however , that, in addition to any vote of the holders of any class or series of stock of Cara required by law or by Cara’s amended and restated certificate of incorporation, such action by stockholders shall require the affirmative vote of the holders of at least 66 2 ∕ 3 % of the voting power of all of the then-outstanding shares of Cara common stock entitled to vote generally in the election of directors, voting together as a single class.

#### Forum Selection

#### Tvardi
Tvardi’s amended and restated certificate of incorporation provides that unless Tvardi consents in writing to the selection of an alternative forum, the Court of Chancery in the State of Delaware shall be the sole and exclusive forum for (i) any derivative action or proceeding brought on behalf of Tvardi, (ii) any action