Company: CMA
Filing Date: 2025-11-25
Form Type: DEFM14A
Source: 0001193125-25-297173
Chunk: 6

Company: COMERICA INC
Filing Date: 2025-11-25
Form: DEFM14A
Chunk 6
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 by calling toll-free at (877) 717-3926or collect at (212) 750-5833.You will not be charged for any of these documents that you request. See section titled “ Where You Can Find More Information” beginning on page 179 of the accompanying joint proxy statement/prospectus for further information.

Fifth Third Bancorp 38 Fountain Square Plaza Cincinnati, Ohio 45263 NOTICE OF SPECIAL MEETING OF FIFTH THIRD SHAREHOLDERS To Fifth Third shareholders: On October 5, 2025, Fifth Third Bancorp (“Fifth Third”), Fifth Third Financial Corporation (“Fifth Third Intermediary”), Comerica Incorporated (“Comerica”) and Comerica Holdings Incorporated (“Comerica Holdings”) entered into an Agreement and Plan of Merger (as may be amended, modified or supplemented from time to time in accordance with its terms, the “merger agreement”), a copy of which is attached as Annex Ato the accompanying joint proxy statement/prospectus. A summary of the merger agreement is included in the section of the accompanying joint proxy statement/prospectus entitled “ The Merger Agreement” beginning on page 119, and each of the Merger Agreement and such summary are incorporated by reference into this notice to the same extent as if fully set forth herein. NOTICE IS HEREBY GIVEN that a special meeting (the “Fifth Third special meeting”) of holders of Fifth Third common stock (such holders, the “Fifth Third common shareholders”) and holders of Fifth Third 6.00% Non-CumulativePerpetual Class B Preferred Stock, Series A (“Fifth Third preferred stock,”) or depositary shares in respect thereof (such holders, the “Fifth Third voting preferred shareholders” and together with the Fifth Third common shareholders, the “Fifth Third voting shareholders”) will be held virtually via the Internet on January 6, 2026 at 9:00 a.m., Eastern Standard Time at www.virtualshareholdermeeting.com/FITB2026SM . We are pleased to notify you of and invite you to the Fifth Third special meeting. At the Fifth Third special meeting you will be asked to vote on the following matters:

| • |     | A proposal to approve the issuance of Fifth Third common stock in connection with the merger of Comerica with and                                                                                                                                     
 into Fifth Third Intermediary as merger consideration to holders of Comerica common stock pursuant to the merger agreement, (including for purposes of complying with NASDAQ Rule 563