Company: HRTX
Filing Date: 2025-09-09
Form Type: S-3
Source: 0000950170-25-113830
Chunk: 46

Company: HERON THERAPEUTICS, INC. /DE/
Filing Date: 2025-09-09
Form: S-3
Chunk 46
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 to, the SEC. The information contained in, or that can be accessed through, our website is not part of, and is not incorporated into, this prospectus or any accompanying prospectus supplement.

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INCORPORATION OF DOCUMENTS BY REFERENCE</div>

The SEC allows us to “incorporate by reference” the information we file with it, which means that we can disclose important information to you by referring you to those documents. The information that is incorporated by reference is considered to be part of this prospectus, and the information that we file later with the SEC will automatically update and supersede this information. We incorporate by reference the documents listed below and any future filings with the SEC under Section 13(a), 13(c), 14 or 15(d) of the Exchange Act between the date of this prospectus and the termination of the offering of the securities:

our Annual Report on Form 10-K for the year ended December 31, 2024 , filed with the SEC on February 27, 2025;

our Quarterly Reports on Form 10-Q for the periods ended March 31, 2025 and June 30, 2025 , filed with the SEC on May 6, 2025 and August 8, 2025, respectively;

the information specifically incorporated by reference into our Annual Report on Form 10-K for the year ended December 31, 2024 from our Definitive Proxy Statement on Schedule 14A, filed with the SEC on April 30, 2025;

our Current Reports on Form 8-K filed with the SEC on February 20, 2025 , April 29, 2025 , May 6, 2025 (Items 8.01 and 9.01), June 18, 2025 , August 8, 2025 , August 12, 2025 (Item 1.01) and August 12, 2025 (Items 1.01, 5.03, 8.01 and 9.01), August 15, 2025 , and August 28, 2025 .

the description of the Company’s Common Stock contained in Amendment No. 3 to that certain registration statement on Form 8-A , filed with the SEC on July 6, 2017 pursuant to Section 12 of the Exchange Act, including any amendment or report filed for the purpose of updating that description;

the description of the