Company: FITBI
Filing Date: 2025-10-06
Form Type: 425
Source: 0001193125-25-230874
Chunk: 9

Company: FIFTH THIRD BANCORP
Filing Date: 2025-10-06
Form: 425
Chunk 9
---
 our customers for nearly two centuries,” said Curt Farmer, Chairman, President and CEO of Comerica. “Joining with Fifth Third—with its strengths in retail, payments and
digital—allows us to build on our leading commercial franchise and further serve our customers with enhanced capabilities across more markets, while staying true to our core values. I am confident that we will be better together, and our
customers, shareholders and communities will benefit.”

To ensure business and client continuity, leadership will include representation from both
organizations. Farmer will assume the role of Vice Chair and Peter Sefzik, Comerica’s chief banking officer, will lead Fifth Third’s Wealth & Asset Management business. Three members of Comerica’s Board will join Fifth
Third’s Board of Directors following the transaction close. Farmer will also join Fifth Third’s Board of Directors upon retirement. The transaction is anticipated to close at the end of the first quarter of 2026. The transaction is
subject to shareholder approvals for both Fifth Third and Comerica, customary regulatory approvals and closing conditions.

“Our disciplined
approach to M&A is grounded in the belief that anything we do must be strategic, make financial sense, and expand the reach of our industry-leading products and services – and this combination checks every box,” Spence continued.
“We’re thrilled to build our future with a franchise we have long admired.”

Investor Call Fifth Third will hold a live investor presentation call on October 6, 2025 at 8:00 AM ET. The conference call will be accessible through live webcast via Fifth Third’s Investor Relations website at www.53.com(click on “About Us” and then “Investor Relations”). Those unable to listen to the live webcast may access a webcast replay through the Fifth Third Investor Relations website at the same web address. Advisors Goldman Sachs & Co. LLC is serving as exclusive financial advisor to Fifth Third and Sullivan & Cromwell LLP is serving as legal advisor. J.P. Morgan Securities LLC is serving as lead financial advisor to Comerica and Wachtell, Lipton, Rosen & Katz is serving as legal advisor. Keefe, Bruyette & Woods, a Stifel Company, also served as financial advisor to Comerica. Contacts Fifth Third

| • |     | Jennifer Hendricks Sullivan (Media Relations) - jennifer.hendricks.sullivan@53.com |

| • |     | Matt Curoe (Investor Relations) - matt.curoe@53.com | 513-534-