Company: AX
Filing Date: 2025-09-17
Form Type: 424B5
Source: 0001299709-25-000159
Chunk: 2

Company: Axos Financial, Inc.
Filing Date: 2025-09-17
Form: 424B5
Chunk 2
---
 incorporated by reference in this prospectus supplement and the accompanying prospectus.

The Notes are not savings accounts, deposits or other obligations and are not insured by the Federal Deposit Insurance Corporation (the

#### “

#### FDIC
#### ”)

or any other government agency or instrumentality, and they are not obligations of, or guaranteed by, the Bank or our nonbank subsidiaries.

#### None of the Securities and Exchange Commission (
#### “

#### SEC
#### ”)

, any state securities commission, the FDIC, the Federal Reserve, the Office of the Comptroller of the Currency, or any other regulatory body has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus supplement or the accompanying prospectus. Any representation to the contrary is a criminal offense.

| Joint Book-Running Managers |     |                         |
| Co-Managers                 |     |                         |
| B. Riley Securities         |     | Janney Montgomery Scott |

<div align='center'>The date of this prospectus supplement is September 16, 2025.</div>

### TABLE OF CONTENTS

### PROSPECTUS SUPPLEMENT
We include cross-references in this prospectus supplement to captions elsewhere in these materials where you can find further related discussions. The following table of contents tells you where to find these captions:

### PROSPECTUS SUPPLEMENT
|                                                           |     | Page |
| ABOUT THIS PROSPECTUS SUPPLEMENT                          |     | S-iv |
| INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE           |     | S-iv |
| EXTENDED SETTLEMENT                                       |     | S-v  |
| CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS |     | S-1  |
| PROSPECTUS SUPPLEMENT SUMMARY                             |     | S-3  |
| THE OFFERING                                              |     | S-4  |
| RISK FACTORS                                              |     | S-8  |
| USE OF PROCEEDS                                           |     | S-15 |
| CAPITALIZATION                                            |     | S-15 |
| CONSOLIDATED CAPITAL RATIOS                               |     | S-16 |
| DESCRIPTION OF NOTES                                      |     | S-16 |
| MATERIAL U.S. FEDERAL INCOME TAX CONSIDERATIONS           |     | S-30 |
| CERTAIN ERISA CONSIDERATIONS                              |     | S-34 |
| UNDERWRITING                                              |     | S-35 |
| LEGAL MAT