Company: PFSA
Filing Date: 2025-10-29
Form Type: 424B3
Source: 0001213900-25-103174
Chunk: 250

Company: Profusa, Inc.
Filing Date: 2025-10-29
Form: 424B3
Chunk 250
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 our Common
Stock that remained in effect as of the date of the Purchase Agreement. Ascent has agreed that during the term of the Purchase Agreement,
none of Ascent, any of its officers, or any entity managed or controlled by Ascent, will enter into or effect, directly or indirectly,
any of the foregoing transactions either for Ascent’s own principal account or for the principal account of any such entity managed
or controlled by Ascent.

We have advised Ascent that
it is required to comply with Regulation M promulgated under the Exchange Act. With certain exceptions, Regulation M precludes
Ascent, any affiliated purchasers, and any broker-dealer or other person who participates in the distribution from bidding for or
purchasing or attempting to induce any person to bid for or purchase any security which is the subject of the distribution until the entire
distribution is complete. Regulation M also prohibits any bids or purchases made in order to stabilize the price of a security in
connection with the distribution of that security. All of the foregoing may affect the marketability of the securities offered by this
prospectus.

This offering will terminate
on the date that all Purchase Shares offered by this prospectus have been sold by Ascent.

Our Common Stock is currently
listed on Nasdaq under the symbol “PFSA”.

Ascent and/or one or more
of its affiliates has provided, currently provides and/or from time to time in the future may provide various investment banking and other
financial services for us and/or one or more of our affiliates that are unrelated to the transactions contemplated by the Purchase Agreement
and the offering of Purchase Shares for resale by Ascent to which this prospectus relates, for which investment banking and other financial
services they have received and may continue to receive customary fees, commissions and other compensation from us, aside from any discounts,
fees and other compensation that Ascent has received and may receive in connection with the transactions contemplated by the Purchase
Agreement, including (i) the Commitment Warrants exercisable for up to 900,000 Commitment Warrant Shares we issued to Ascent as consideration
for its irrevocable commitment to purchase shares of our Common Stock from us at our direction under the Purchase Agreement, (ii) the
3.0% fixed discount to current market prices of our Common Stock reflected in the purchase prices payable by Ascent for our Common Stock
that we may require it to purchase from us from time to time in one or more Purchases under the Purchase Agreement,