Company: SMNR
Filing Date: 2025-07-23
Form Type: S-4/A
Source: 0001193125-25-163401
Chunk: 1061

Company: Semnur Pharmaceuticals, Inc.
Filing Date: 2025-07-23
Form: S-4/A
Chunk 1061
---
'>F-16</div>

#### conditional. No waiver of any breach of any agreement or provision herein contained shall be deemed a waiver of any preceding or succeeding breach thereof nor of any other agreement or provision herein contained. No waiver or extension of time for performance of any obligations or acts shall be deemed a waiver or extension of the time for performance of any other obligations or acts.5.15Holder Information. Each Holder agrees, if requested in writing, to represent to the Company the total number of Registrable Securities held by such Holder in order for the Company to make determinations hereunder.[SIGNATURE PAGES FOLLOW]F-17
IN WITNESS WHEREOF, the undersigned have caused this Agreement to be executed as of the date first written above.

| SEMNUR PHARMACEUTICALS, INC.                 |     |                   |
| By:                                          |     |                   |
|                                              |     | Name: Jaisim Shah |
| Title: Chief Executive Officer and President |     |                   |
| EXISTING HOLDERS:                            |     |                   |
| DENALI CAPITAL GLOBAL INVESTMENTS LLC        |     |                   |
| By:                                          |     |                   |
|                                              |     | Name:             |
|                                              |     | Title:            |
| By:                                          |     |                   |
|                                              |     | Huifeng Chang     |
| By:                                          |     |                   |
|                                              |     | Lei Huang         |
| By:                                          |     |                   |
|                                              |     | Jim Mao           |
| By:                                          |     |                   |
|                                              |     | You “Patrick” Sun |
| By:                                          |     |                   |
|                                              |     | Kevin Vassily     |

[Signature Page to Amended and Restated Registration Rights Agreement] F-18

| NEW HOLDER:            |     |                                              |
| SCILEX HOLDING COMPANY |     |                                              |
| By:                    |     |                                              |
|                        |     | Name: Jaisim Shah                            |
|                        |     | Title: Chief Executive Officer and President |

[Signature Page to Amended and Restated Registration Rights Agreement] F-19

**Annex G**

<div align='center'>**CERTIFICATE OF DESIGNATIONS

OF

SEMNUR PHARMACEUTICALS, INC.

a Delaware corporation

(Pursuant to Section151 of the

General Corporation Law of the State of Delaware)**</div>

Semnur Pharmaceuticals, Inc.,