Company: APM
Filing Date: 2025-12-05
Form Type: 424B5
Source: 0001213900-25-118752
Chunk: 137

Company: Aptorum Group Ltd
Filing Date: 2025-12-05
Form: 424B5
Chunk 137
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 in our operating
entities, none of which are located in mainland China, although the current VIE over which we maintain economic control (Libra Sciences
Limited), is incorporated under the laws of Cayman Islands and conducts operations in Hong Kong. Our principal executive offices
are located in Europe, but our principal place of business is in Hong Kong, a special administrative region of China. The PRC government
currently does not exert direct influence and discretion over the manner in which we conduct our business activities outside of mainland
China, however, there is no guarantee that we will not be subject to such direct influence or discretion in the future due to changes
in laws or other unforeseeable reasons or as a result of our future expansion or acquisition of operations in mainland China. See “— Our
business, financial condition and results of operations, and/or the value of Aptorum Class A ordinary shares or our ability to offer
or continue to offer securities to investors may be materially and adversely affected to the extent the laws and regulations of the PRC
become applicable to a company such as us.”

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We currently do not have plans
to expand our operation or acquire any operation in the mainland China. However, if we were to become subject to the direct intervention
or influence of the PRC government at any time due to changes in laws or other unforeseeable reasons or as a result of our future development,
expansion or acquisition of operations in the PRC, it may require a material change in our operations and/or result in increased costs
necessary to comply with existing and newly adopted laws and regulations or penalties for any failure to comply. In addition, the market
prices of Aptorum Class A ordinary shares could be adversely affected as a result of anticipated negative impacts of any such government
actions, as well as negative investor sentiment towards Hong Kong-based companies subject to direct PRC government oversight and
regulation, regardless of our actual operating performance. There can be no assurance that the Chinese government would not intervene
in or influence our operations at any time.

We were not required to obtain
permission from the PRC government to list on a U.S. securities exchange, however there is no guarantee that this will continue to
be the case in the future in relation to the continued listing of our securities on a securities exchange outside of the PRC, or even
when such permission is obtained, it will not be subsequently denied or rescinded. Any actions by the PRC government to exert more oversight