Company: DRTSW
Filing Date: 2025-04-28
Form Type: 424B5
Source: 0001213900-25-035799
Chunk: 13

Company: Alpha Tau Medical Ltd.
Filing Date: 2025-04-28
Form: 424B5
Chunk 13
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 weighted-average exercise price of $4.39 per share;                    |

| ● | 857,899 ordinary shares issuable upon the vesting of RSUs outstanding as of December 31, 2024; |

| ● | 15,747,561 ordinary shares issuable upon the exercise of existing warrants outstanding as of December 
 31, 2024 at a weighted-average exercise price of $11.50 per share;                                    |

| ● | 11,383,655 ordinary shares reserved for future issuance under our 2021 Share Incentive Plan as of December 
 31, 2024; and                                                                                              |

| ● | 2,673,455 ordinary shares reserved for future issuance under our 2021 Employee Share Purchase Plan as 
 of December 31, 2024.                                                                                 |

Unless otherwise indicated, all information contained in this prospectus supplement assumes no exercise or conversion of the options or existing warrants or vesting of RSUs. To the extent that outstanding options and warrants are exercised, RSUs vest, or new options or RSUs are issued under our share-based compensation plans, investors purchasing our ordinary shares in this offering will experience further dilution. In addition, we may choose to raise additional capital due to market conditions or strategic considerations even if we believe we have sufficient funds for our current or future operating plans. To the extent that we raise additional capital through the sale of equity or convertible debt securities, the issuance of these securities could result in further dilution to our shareholders.

<div align='center'>S-6

RISK FACTORS</div>

Investing in our ordinary
shares involves a high degree of risk. Before making a decision to invest in our ordinary shares, you should consider carefully the risks
and uncertainties described under the heading “Risk Factors” contained or incorporated by reference in this prospectus supplement
and the accompanying base prospectus, including the risk factors listed below and the ones incorporated by reference herein from our Annual
Report on Form 20-F for the year ended December 31, 2024, or Annual Report, as may be updated by our subsequent annual reports and
other filings we make with the SEC. The risks described in these documents are not the only ones we face. There may be other unknown or
unpredictable economic, business, competitive, regulatory or other factors that could harm our future results. Past financial performance
may not be a reliable indicator of future performance, and historical trends should not be used to anticipate results or trends in future
period