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XGBoost โ€” Fentanyl Overdose Rate Forecasting

Author: Ansh Gupta

Overview

An XGBoost regression model for forecasting census tract-level fentanyl/opioid overdose rates in King County, Washington. The model integrates American Community Survey (ACS) census data, Group-Based Trajectory Modeling (GBTM) cluster assignments, and historical overdose rates to predict future overdose rates per 100,000 population.

Performance (5-Fold Cross-Validation)

Metric Value
Rยฒ 0.923
MAE 5.79 per 100,000
RMSE 9.47 per 100,000
Spearman ฯ 0.929
Top-10 Overlap 90.0%
BPR K=10 100.0%
Top-20 Overlap 100.0%
BPR K=20 100.0%
Top-50 Overlap 86.0%
BPR K=50 98.0%
Mean BPR (K=5โ€“200) 97.6%

Features

Feature Description
Med_HHD_Inc_Thousands_ACS__ Median household income (thousands)
pct_Renter_Occp_HU_ACS__ % renter-occupied housing units
pct_Vacant_Units_ACS__ % vacant housing units
pct_Not_HS_Grad_ACS__ % without high school diploma
pct_College_ACS__ % with college degree
pct_NH_Blk_alone_ACS__ % non-Hispanic Black population
Pct_No_Health_Ins_CALCULATED_ACS__ % without health insurance
Med_HHD_Inc_Thousands_ACS___Neighbor_Avg Average median income of 3 nearest neighbor tracts
pct_Vacant_Units_ACS___Neighbor_Avg Average vacancy rate of 3 nearest neighbor tracts
pct_Renter_Occp_HU_ACS___Neighbor_Avg Average renter rate of 3 nearest neighbor tracts
Rate_Independent Prior-year overdose rate (per 100,000)
Cluster_1 GBTM trajectory cluster 1 indicator
Cluster_2 GBTM trajectory cluster 2 indicator
Cluster_3 GBTM trajectory cluster 3 indicator

Hyperparameters

Parameter Value
n_estimators 500
max_depth 3
learning_rate 0.01
subsample 1.0
colsample_bytree 1.0
objective reg:squarederror

Validation

  • Temporal: Out-of-time forecast (trained on โ‰ค2024 data, predicting 2025 TTM rates)
  • Cross-validation: 5-fold CV โ€” every tract predicted by a model never trained on it
  • Geographic: Cross-regional transfer validated on Los Angeles County, CA

Training Data

  • Region: King County, Washington (463 census tracts)
  • Target: Overdose death rate per 100,000 (2025 trailing twelve months)
  • Census data: ACS 5-year estimates (2019โ€“2023)

Usage

import xgboost as xgb
import pandas as pd

# Load model
model = xgb.Booster()
model.load_model("xgboost_model.json")

# Prepare features (must match order in features.json)
dtest = xgb.DMatrix(your_features_df)
predictions = model.predict(dtest)

Files

File Description
xgboost_model.json Trained XGBoost model (native JSON format)
xgboost_model.pkl Trained XGBoost model (pickle format)
features.json Feature names and target variable
hyperparameters.json Tuned hyperparameters
training_data.csv Full training dataset (463 tracts)

License

MIT

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