Instructions to use HuggingFaceBio/Carbon-500M with libraries, inference providers, notebooks, and local apps. Follow these links to get started.

Libraries

How to use HuggingFaceBio/Carbon-500M with Transformers:

# Use a pipeline as a high-level helper
from transformers import pipeline

pipe = pipeline("text-generation", model="HuggingFaceBio/Carbon-500M")
messages = [
    {"role": "user", "content": "Who are you?"},
]
pipe(messages)

# Load model directly
from transformers import AutoTokenizer, AutoModelForCausalLM

tokenizer = AutoTokenizer.from_pretrained("HuggingFaceBio/Carbon-500M")
model = AutoModelForCausalLM.from_pretrained("HuggingFaceBio/Carbon-500M")
messages = [
    {"role": "user", "content": "Who are you?"},
]
inputs = tokenizer.apply_chat_template(
	messages,
	add_generation_prompt=True,
	tokenize=True,
	return_dict=True,
	return_tensors="pt",
).to(model.device)

outputs = model.generate(**inputs, max_new_tokens=40)
print(tokenizer.decode(outputs[0][inputs["input_ids"].shape[-1]:]))

Notebooks
Google Colab
Kaggle
Local Apps

vLLM

How to use HuggingFaceBio/Carbon-500M with vLLM:

Install from pip and serve model

# Install vLLM from pip:
pip install vllm
# Start the vLLM server:
vllm serve "HuggingFaceBio/Carbon-500M"
# Call the server using curl (OpenAI-compatible API):
curl -X POST "http://localhost:8000/v1/chat/completions" \
	-H "Content-Type: application/json" \
	--data '{
		"model": "HuggingFaceBio/Carbon-500M",
		"messages": [
			{
				"role": "user",
				"content": "What is the capital of France?"
			}
		]
	}'

Use Docker

docker model run hf.co/HuggingFaceBio/Carbon-500M

SGLang

How to use HuggingFaceBio/Carbon-500M with SGLang:

Install from pip and serve model

# Install SGLang from pip:
pip install sglang
# Start the SGLang server:
python3 -m sglang.launch_server \
    --model-path "HuggingFaceBio/Carbon-500M" \
    --host 0.0.0.0 \
    --port 30000
# Call the server using curl (OpenAI-compatible API):
curl -X POST "http://localhost:30000/v1/chat/completions" \
	-H "Content-Type: application/json" \
	--data '{
		"model": "HuggingFaceBio/Carbon-500M",
		"messages": [
			{
				"role": "user",
				"content": "What is the capital of France?"
			}
		]
	}'

Use Docker images

docker run --gpus all \
    --shm-size 32g \
    -p 30000:30000 \
    -v ~/.cache/huggingface:/root/.cache/huggingface \
    --env "HF_TOKEN=<secret>" \
    --ipc=host \
    lmsysorg/sglang:latest \
    python3 -m sglang.launch_server \
        --model-path "HuggingFaceBio/Carbon-500M" \
        --host 0.0.0.0 \
        --port 30000
# Call the server using curl (OpenAI-compatible API):
curl -X POST "http://localhost:30000/v1/chat/completions" \
	-H "Content-Type: application/json" \
	--data '{
		"model": "HuggingFaceBio/Carbon-500M",
		"messages": [
			{
				"role": "user",
				"content": "What is the capital of France?"
			}
		]
	}'

Docker Model Runner
How to use HuggingFaceBio/Carbon-500M with Docker Model Runner:
```
docker model run hf.co/HuggingFaceBio/Carbon-500M
```

R interface for Carbon — collaboration interest

by AncientHearings - opened about 17 hours ago

Discussion

AncientHearings

about 17 hours ago

Hi HuggingFace Bio team,

Congratulations on the Carbon release; impressive work, especially the FNS branch for base-pair level scoring.

I'm the developer of EvoR (github.com/BDB-Genomics/EvoR), an R interface to the Evo 2 genomic foundation model via NVIDIA BioNeMo. The R/Bioconductor genomics community has essentially zero native access to models like Carbon right now, and I think that's worth fixing.

I'd be interested in building a CarbonR package — an R-native interface to Carbon-3B/8B — and would love to do it in collaboration with your team rather than in isolation. Happy to discuss scope, credit, and how it fits into the HuggingFaceBio ecosystem.

Would you be open to a quick conversation?

Best,
Himanshu Bhandary
BDB-Genomics | hb2024ms@gmail.com
github.com/BDB-Genomics

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