Document ID: chunk:federal_register_of_legislation:F2022L00003:reg:9:p2
Version: federal_register_of_legislation:F2022L00003
Segment Type: reg
Provision Reference: reg 9 (pt 2/2)
Character Range: 8215–9898

a neurological disease, neurodegenerative disease or a paraneoplastic neurological syndrome, where the disease or syndrome involves the hypothalamus, midbrain or brainstem, within the 2 years before the clinical worsening of narcolepsy;
            Note: Examples of neurological diseases, neurodegenerative diseases or paraneoplastic neurological syndromes that can involve the hypothalamus, midbrain or brainstem include:
               (i)              cerebrovascular accident;
               (ii)            disseminated encephalomyelitis;
               (iii)          hypoxic cerebral insult;
               (iv)           multiple sclerosis;
               (v)            neuromyelitis optica spectrum disorder; and
               (vi)           Parkinson's disease.
(12)      having:
(a)          a benign or malignant neoplasm; or
(b)          a non-malignant space occupying lesion;

involving the hypothalamus, midbrain or brainstem within the 2 years before the clinical worsening of narcolepsy;
             Note 1: Examples of neoplasms that can involve the hypothalamus, midbrain or brainstem include lymphoma, glioma and craniopharyngioma.
             Note 2: Examples of non-malignant space occupying lesions that can involve the hypothalamus, midbrain or brainstem include neurosarcoidosis and vascular malformations.
(13)      receiving the adjuvanted influenza H1N1 vaccine PandemrixTM within the 2 years before the clinical worsening of narcolepsy;
(14)      having infection of the pharynx with Streptococcus pyogenes within the 3 years before the clinical worsening of narcolepsy;
(15)      inability to obtain appropriate clinical management for narcolepsy.