Document ID: chunk:federal_register_of_legislation:F2022L00266:reg:6
Version: federal_register_of_legislation:F2022L00266
Segment Type: reg
Provision Reference: reg 6
Character Range: 1550–3233

6               Kind of injury, disease or death to which this Statement of Principles relates
(1)          This Statement of Principles is about eosinophilic oesophagitis and death from eosinophilic oesophagitis.
Meaning of eosinophilic oesophagitis
(2)          For the purposes of this Statement of Principles, eosinophilic oesophagitis means a chronic, immune-mediated oesophageal disease, characterised by symptoms related to oesophageal dysfunction, together with eosinophil-predominant inflammation of the oesophageal epithelium.
             Note 1: Typical symptoms of oesophageal dysfunction in adults include difficulty swallowing, chest pain, upper abdominal pain, heartburn and acute food bolus obstruction.
             Note 2: Eosinophil-predominant infiltration of the oesophageal epithelium is demonstrated by peak values of at least 15 eosinophils per high-power field on oesophageal biopsy.
             Note 3: Endoscopic findings which may increase suspicion of a diagnosis of eosinophilic oesophagitis include rings, furrows, exudates, oedema, stricture, narrowing and crepe-paper mucosa.
             Note 4: A clinical assessment should fully evaluate any condition that could account for oesophageal tissue eosinophilia, including gastro-oesophageal reflux disease, Crohn disease, infections and connective tissue disorders.
Death from eosinophilic oesophagitis
(3)          For the purposes of this Statement of Principles, eosinophilic oesophagitis, in relation to a person, includes death from a terminal event or condition that was contributed to by the person's eosinophilic oesophagitis.
Note: terminal event is defined in the Schedule 1 – Dictionary.