Document ID: chunk:federal_register_of_legislation:F2023L00518:reg:7
Version: federal_register_of_legislation:F2023L00518
Segment Type: reg
Provision Reference: reg 7
Character Range: 1677–2741

7               Kind of injury, disease or death to which this Statement of Principles relates
(1)          This Statement of Principles is about Gaucher disease and death from Gaucher disease.
Meaning of Gaucher disease
(2)          For the purposes of this Statement of Principles, Gaucher disease means a genetic disorder of sphingolipid metabolism which involves a deficiency of the lysosomal enzyme glucocerebrosidase, leading to accumulation of glucocerebroside and other glycolipids in macrophages in various organs of the body.
Note 1: Accumulation of glucocerebroside and glycolipids in macrophages can occur in the spleen, liver, bone marrow and bone.
Note 2: Clinical manifestations include splenomegaly, hepatomegaly, thrombocytopaenia and anaemia.
Death from Gaucher disease
(3)          For the purposes of this Statement of Principles, Gaucher disease, in relation to a person, includes death from a terminal event or condition that was contributed to by the person's Gaucher disease.
Note: terminal event is defined in the Schedule 1 – Dictionary.