Document ID: chunk:federal_register_of_legislation:F2025L00212:clause:1_1646
Version: federal_register_of_legislation:F2025L00212
Segment Type: clause
Provision Reference: sch 1 cl 1646
Character Range: 794305–796050

1646                                      CURCUMA LONGA                                                                                    A, E, H   When used in oral medicines as an active ingredient, the following warning statement is required on the medicine label:
                                                                                                                                                     'In very rare cases, Curcuma species may harm the liver. Stop use and see a doctor if you have yellowing skin/eyes or unusual: fatigue, nausea, appetite loss, abdominal pain, dark urine, or itching.'
                                                                                                                                                     When used in oral medicines the maximum daily dose of (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione in the medicine must not provide more than:
                                                                                                                                                     (a) 36 mg for children from 2-3 years (inclusive);
                                                                                                                                                     (b) 48 mg for children from 4-11 years (inclusive); and
                                                                                                                                                     (c) 123 mg for children from 12-17 years (inclusive).
                                                                                                                                                     Not permitted for use in children aged below 2 years.