Document ID: chunk:federal_register_of_legislation:F2016L00424:front:0:p20
Version: federal_register_of_legislation:F2016L00424
Segment Type: other
Provision Reference: 
Character Range: 54136–57135

and misunderstanding and should not be used.
For health effects where information is not available, this should be clearly stated. Health effects should be described accurately and relevant distinctions made. For example, allergic contact dermatitis and irritant contact dermatitis should be distinguished from each other.
Where there is a substantial amount of test data on the hazardous chemical, the results should be summarised for example, by grouping toxicological data by the route of exposure.
Information should also be provided on the relevant negative data. Information to support negative test results should be included, for example "carcinogenicity studies in the rat have shown no significant increase in the incidence of cancer".

Information on possible routes of exposure
Information should be provided on the possible routes of exposure and the effects of the hazardous chemical via each route of exposure, that is, through ingestion (swallowing), inhalation or skin/eye exposure. A statement should be made if health effects are not known. Statements such as "Ingestion is not expected to occur" or "Ingestion should be avoided" are not acceptable.
Information on all routes of exposure should be provided as it is not possible to predict how
a chemical will be used in a workplace or the most likely exposure route.

Early onset symptoms related to exposure
Information should be provided on early symptoms associated with exposure to the hazardous chemical, its ingredients or known by-products. It should include information on the symptoms related to the physical, chemical and toxicological characteristics of the hazardous chemical following exposure related to the intended uses. This section should describe the first symptoms at the lowest exposures through to the consequences of severe exposure, for example, "Headaches and dizziness may occur, proceeding to fainting or unconsciousness; large doses may result in coma and death".

Delayed health effects from exposure
Information should be provided on whether delayed or immediate effects can be expected after short or long term exposure consistent with the classification of the chemical. Information should include acute and chronic health effects relating to human exposure to the hazardous chemical.
Where human data is not available, animal data should be summarised and the species clearly identified. The SDS should indicate whether toxicological data is based on human or animal data. Classifications or studies from government or international agencies may be used, for example "Has been classified as a probable human carcinogen by the International Agency for Research
on Cancer". Where data on chronic effects is not available, it is recommended that the SDS take
a precautionary approach to health effects from exposure.

Exposure levels and health effects
The SDS should provide information on the dose, concentration or conditions of exposure that may cause adverse health effects. Where appropriate,