Document ID: chunk:federal_register_of_legislation:F2024L01024:front:0:p93
Version: federal_register_of_legislation:F2024L01024
Segment Type: other
Provision Reference: 
Character Range: 264228–267343

virus;
10. Peste‑des‑petits ruminants virus;
11. Porcine Teschovirus;
12. Rinderpest virus;
13. Sheeppox virus;
14. Teschen disease virus;
15. Vesicular stomatitis virus;
16. Lumpy skin disease virus;
17. African horse sickness virus;
18. Swine vesicular disease virus.
1. C. 352. b. Mycoplasmas, whether natural, enhanced or modified, either in the form of "isolated live cultures" or as material including living material which has been deliberately inoculated or contaminated with such cultures, as follows:
1. Mycoplasma mycoides subspecies mycoides SC (small colony);
2. Mycoplasma capricolum subspecies capripneumoniae (strain F38);
Note: 1C352 does not apply to "vaccines".
1. C. 353. Any 'genetically-modified organism' which contains, or 'genetic element' that codes for, any of the following:
a. Any gene, genes, translated product, or translated products, specific to any listed virus; or
b. Any gene or genes specific to any listed bacterium or fungus, and which:
1. In itself or through its transcribed or translated products represents a significant hazard to human, animal or plant health; or
2. Could 'endow or enhance pathogenicity'; or
c. Any listed toxins or their sub‑units.
Technical Notes:
1. 'Genetically‑modified organisms' include organisms in which the nucleic acid sequences have been created or altered by deliberate molecular manipulation.
2. 'Genetic elements' include, inter alia: chromosomes, genomes, plasmids, transposons, vectors, and inactivated organisms containing recoverable nucleic acid fragments, whether genetically modified or unmodified, or chemically synthesized in whole or in part. For the purposes of the genetic elements control, nucleic acids from an inactivated organism, virus, or sample are considered 'recoverable' if the inactivation and preparation of the material is intended or known to facilitate isolation, purification, amplification, detection, or identification of nucleic acids.
3. 1C353 does not apply to nucleic acid sequences of shiga toxin producing Escherichia coli of serogroups O26, O45, O103, O104, O111, O121, O145, O157, and other shiga toxin producing serogroups, other than those genetic elements coding for shiga toxin, or for its subunits.
4. 'Endow or enhance pathogenicity' is defined as when the insertion or integration of the nucleic acid sequence or sequences is/are likely to enable or increase a recipient organism's ability to be used to deliberately cause disease or death. This might include alterations to, inter alia: virulence, transmissibility, stability, route of infection, host range, reproducibility, ability to evade or suppress host immunity, resistance to medical countermeasures, or detectability.
Note: 1C353 applies to the viruses, bacteria, fungi and toxins listed in 1C351, 1C352 and 1C354.
1. C. 354. Plant pathogens, as follows:
a. Viruses, whether natural, enhanced or modified, either in the form of "isolated live cultures" or as material including living material which has been deliberately inoculated or contaminated with such cultures, as follows:
1. Andean Potato latent tymovirus;
2. Potato spindle