Document ID: chunk:federal_register_of_legislation:F2021L01913:reg:7:p1
Version: federal_register_of_legislation:F2021L01913
Segment Type: reg
Provision Reference: reg 7 (pt 1/2)
Character Range: 1700–5433

7               Kind of injury, disease or death to which this Statement of Principles relates
(1)          This Statement of Principles is about hyperthyroidism and thyrotoxicosis and death from hyperthyroidism and thyrotoxicosis.
     Meaning of hyperthyroidism
(2)          For the purposes of this Statement of Principles, hyperthyroidism:
(a)           means a functional endocrine disorder in which the thyroid gland synthesises and secretes excessive amounts of thyroid hormone sufficient to produce clinical symptoms and signs of thyroid hyperfunction or to warrant medical treatment; and
(b)          excludes:
                (i)            euthyroid hyperthyroxinaemia;
                (ii)         gestational transient thyrotoxicosis;
                (iii)       Graves disease;
                (iv)        sick euthyroid syndrome; and
                (v)          toxic multinodular goitre and toxic thyroid adenoma.
            Note 1: Hyperthyroidism typically presents with elevated serum concentrations of the thyroid hormones thyroxine (T4) and/or triiodothyronine (T3), and usually with a reduced concentration of thyroid-stimulating hormone.
            Note 2: Clinical symptoms and signs of thyroid hyperfunction are nonspecific and typically include anxiety, emotional lability, weakness, tremor, palpitations, heat intolerance, increased perspiration and weight loss.
            Note 3: Hyperthyroidism due to toxic multinodular goitre or toxic thyroid adenoma is covered by the Statements of Principles concerning goitre.  In the circumstance where hyperthyroidism is due to Graves disease, it is covered by the Statements of Principles concerning Graves disease.
            Note 4: Hyperthyroidism may be acute or chronic.  The acute form may present as thyrotoxic crisis.
Note 5: thyrotoxic crisis is defined in the Schedule 1 - Dictionary.
     Meaning of thyrotoxicosis
(3)          For the purposes of this Statement of Principles, thyrotoxicosis:
(a)           means a functional endocrine disorder that results from the action of inappropriately high thyroid hormone levels in tissues sufficient to produce clinical symptoms and signs of thyroid hyperfunction or to warrant medical treatment; and
(b)           excludes:
                (i)            euthyroid hyperthyroxinaemia;
                (ii)         gestational transient thyrotoxicosis;
                (iii)       Graves disease;
                (iv)        sick euthyroid syndrome; and
                (v)          toxic multinodular goitre and toxic thyroid adenoma.
            Note 1: Inappropriately high thyroid hormone levels in thyrotoxicosis can arise from endogenous or exogenous sources.
            Note 2: Thyrotoxicosis typically presents with elevated serum concentrations of the thyroid hormones thyroxine (T4) and/or triiodothyronine (T3), and usually with a reduced concentration of thyroid-stimulating hormone.
            Note 3: Clinical symptoms and signs of thyroid hyperfunction are nonspecific and typically include anxiety, emotional lability, weakness, tremor, palpitations, heat intolerance, increased perspiration and weight loss.
            Note 4: Thyrotoxicosis due to toxic multinodular goitre or toxic thyroid adenoma is covered by the Statements of Principles concerning goitre. In the circumstance where thyrotoxicosis is a clinical manifestation of Graves disease, it is covered by the Statements of Principles concerning Graves disease.
            Note 5: Thyrotoxicosis may be acute or chronic.  The acute form may present as a thyrotoxic crisis.
            Note 6: thyrotoxic crisis is defined in the Schedule 1 - Dictionary.
     Death from hyperthyroidism or thyrotoxicosis
(4)          For