Document ID: chunk:federal_register_of_legislation:F2013C00288:reg:8:p3
Version: federal_register_of_legislation:F2013C00288
Segment Type: reg
Provision Reference: reg 8 (pt 3/7)
Character Range: 3043582–3046502

organism, system or population is exposed over a continuous or intermittent duration of exposure. It is generally the total amount of a chemical administered to, taken up by, or absorbed by an organism, system, or population.
Doseresponse curve is a graphical representation of a doseresponse relationship.
Doseresponse is the relationship between the amount of chemical administered to, taken up by, or absorbed by an organism, system, or population and the change developed in that organism, system, or population in reaction to the agent.
Effect is the change in the state or dynamics of an organism, system, or population caused by exposure to a chemical.
Expert/professional judgement is the opinion of an authoritative person on a particular subject.
Exposed population are the people who may be exposed to the contaminant. Synonymous with 'receptor'.
Exposure assessment is the evaluation of the exposure of an organism, system, or population to a chemical (and its derivatives).
Exposure is the concentration or amount of a particular chemical that reaches a target organism, system or population at a specific frequency for a defined duration.
Exposure concentration is the exposure mass divided by the contact volume or the exposure mass divided by the mass of contact volume, depending on the medium.
Exposure duration is the length of time over which continuous or intermittent contacts occur between a chemical and the exposed population.
Exposure event is the occurrence of continuous contact between a chemical and an exposed population.
Exposure frequency is the number of exposure events within an exposure duration.
Exposure model is a conceptual or mathematical representation of the exposure process.
Exposure pathway is the means by which a contaminant makes contact with the exposed population.
Exposure route is the way in which a chemical substance enters a target after contact (for example, ingestion, inhalation or dermal absorption).
Exposure scenario is a set of conditions or assumptions about sources, exposure pathways, concentration of contaminants involved, and exposed population (that is, numbers, characteristics, habits) used in the evaluation and quantification of exposure(s) in a given situation.
Genotoxic chemicals are those for which there is adequate evidence of the potential to interact with, and/or modify the function of genetic material and which have the ability to induce tumours via a mechanism involving direct damage to DNA.
Hazard is the inherent property of a contaminant or situation having the potential to cause adverse effects when a population may be exposed to that contaminant.
Hazard identification is the identification of the type and nature of adverse effects where a contaminant has an inherent capacity to cause harm to an exposed population.
Hazard index (HI) is the sum(s) of at least two hazard quotients. It is noted that WHO is moving towards