Document ID: chunk:federal_register_of_legislation:F2022C00581:front:0:p3
Version: federal_register_of_legislation:F2022C00581
Segment Type: other
Provision Reference: 
Character Range: 5869–9143

defined in the Schedule 1 – Dictionary.
     9             Factors that must exist
At least one of the following factors must exist before it can be said that, on the balance of probabilities, hypopituitarism or death from hypopituitarism is connected with the circumstances of a person's relevant service:
(1)          having an autoimmune disorder involving the pituitary gland at the time of the clinical onset of hypopituitarism;
(2)          having a disorder from the specified list of infiltrative, inflammatory or granulomatous disorders, involving the pituitary gland or hypothalamus, at the time of the clinical onset of hypopituitarism;
            Note: specified list of infiltrative, inflammatory or granulomatous disorders is defined in the Schedule 1 - Dictionary.
(3)          having infection with human immunodeficiency virus before the clinical onset of hypopituitarism;
(4)          having a viral, bacterial, fungal or protozoal infection of the pituitary gland, hypothalamus, brain or cerebral meninges, within the five years before the clinical onset of hypopituitarism;
(5)          having Hantavirus haemorrhagic fever with renal syndrome within the five years before the clinical onset of hypopituitarism;
            Note: Hantavirus haemorrhagic fever with renal syndrome is defined in the Schedule 1 - Dictionary.
(6)          having moderate to severe traumatic brain injury within the ten years before the clinical onset of hypopituitarism;
(7)          having a subarachnoid haemorrhage within the ten years before the clinical onset of hypopituitarism;
(8)          having haemorrhage or ischaemia involving the pituitary gland or hypothalamus within the ten years before the clinical onset of hypopituitarism;
Note: Haemorrhage or ischaemia of the pituitary gland includes pituitary apoplexy.
(9)          having severe peripartum or postpartum haemorrhage before the clinical onset of hypopituitarism;
(10)      having surgery involving the pituitary gland, or intracranial surgery, within the ten years before the clinical onset of hypopituitarism;
(11)      undergoing a course of therapeutic radiation for cancer, where the pituitary or hypothalamus was in the field of radiation, before the clinical onset of hypopituitarism;
(12)      having a space occupying lesion that involves, or impinges on, the pituitary gland or hypothalamus at the time of the clinical onset of hypopituitarism;
(13)      taking an immune checkpoint inhibitor or an interferon within the one year before the clinical onset of hypopituitarism;
Note: immune checkpoint inhibitor is defined in the Schedule 1 - Dictionary.
(14)      for lymphocytic hypophysitis only, being pregnant within the six months before the clinical onset of hypopituitarism;
Note: lymphocytic hypophysitis is defined in the Schedule 1 - Dictionary.
(15)      having an autoimmune disorder involving the pituitary gland at the time of the clinical worsening of hypopituitarism;
(16)      having a disorder from the specified list of infiltrative, inflammatory or granulomatous disorders, involving the pituitary gland or hypothalamus, at the time of the clinical worsening of hypopituitarism;
            Note: specified list of infiltrative, inflammatory or granulomatous disorders is