Document ID: chunk:federal_register_of_legislation:F2022L00008:reg:7
Version: federal_register_of_legislation:F2022L00008
Segment Type: reg
Provision Reference: reg 7
Character Range: 1644–3632

7               Kind of injury, disease or death to which this Statement of Principles relates
(1)          This Statement of Principles is about Graves disease and death from Graves disease.
Meaning of Graves disease
(2)          For the purposes of this Statement of Principles, Graves disease means a chronic autoimmune disease primarily affecting the thyroid gland, in which thyroid antibodies activate the thyroid-stimulating hormone receptor, causing thyroid hyperplasia and excessive thyroid hormone synthesis and secretion.
             Note 1: The thyroid-stimulating immunoglobulins can also affect the eyes, causing a characteristic ophthalmopathy (Graves orbitopathy), and less commonly the skin, causing a characteristic dermopathy (pretibial myxoedema).
             Note 2: Presenting features typically include a diffuse hyperplastic goitre and hyperthyroidism, although some patients may be euthyroid or hypothyroid during the course of the disease.
Note 3: Graves disease may present as a thyrotoxic crisis.
Note 4: thyrotoxic crisis is defined in the Schedule 1 - Dictionary.
(3)          While Graves disease attracts ICD‑10‑AM code E05.0 or E05.5, in applying this Statement of Principles the meaning of Graves disease is that given in subsection (2).
(4)          For subsection (3), a reference to an ICD-10-AM code is a reference to the code assigned to a particular kind of injury or disease in The International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification (ICD-10-AM), Tenth Edition, effective date of 1 July 2017, copyrighted by the Independent Hospital Pricing Authority, ISBN 978-1-76007-296-4.
Death from Graves disease
(5)          For the purposes of this Statement of Principles, Graves disease, in relation to a person, includes death from a terminal event or condition that was contributed to by the person's Graves disease.
Note: terminal event is defined in the Schedule 1 - Dictionary.