mneb/biomed-ner · Datasets at Hugging Face

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Weed seed inactivation in soil mesocosms via biosolarization with mature compost and tomato processing waste amendments Biosolarization is a fumigation alternative that combines passive solar heating with amendment-driven soil microbial activity to temporarily create antagonistic soil conditions, such as elevated tempe...	{ "entities": { "organism": [ { "text": "Weed", "start": 0, "end": 4 }, { "text": "seed", "start": 5, "end": 9 }, { "text": "tomato", "start": 85, "end": 91 }, { "text": "weed", "start...	[]
Phenotypic and genetic heterogeneity of tumor tissue and circulating tumor cells in patients with metastatic castration-resistant prostate cancer: A report from the PETRUS prospective study Molecular characterization of cancer samples is hampered by tumor tissue availability in metastatic castration-resistant prostate ...	{ "entities": { "phenotype": [ { "text": "genetic heterogeneity", "start": 15, "end": 36 }, { "text": "metastatic", "start": 771, "end": 781 }, { "text": "primary tumors,", "start": 795, "end": 810 }, ...	[]
Impact of Soil Salinity on the Structure of the Bacterial Endophytic Community Identified from the Roots of Caliph Medic (Medicago truncatula) In addition to being a forage crop, Caliph medic (Medicago truncatula) is also a model legume plant and is used for research focusing on the molecular characterization of the in...	{ "entities": { "organism": [ { "text": "Bacterial", "start": 48, "end": 57 }, { "text": "Roots", "start": 99, "end": 104 }, { "text": "Caliph Medic", "start": 108, "end": 120 }, { "text": "Me...	[]
Role of the Membrane for Mechanosensing by Tethered Channels Biologically important membrane channels are gated by force at attached tethers. Here, we generically characterize the nontrivial interplay of force, membrane tension, and channel deformations that can affect gating. A central finding is that minute conical c...	{ "entities": { "cells and their components": [ { "text": "Membrane", "start": 12, "end": 20 }, { "text": "tethers.", "start": 133, "end": 141 } ], "function": [ { "text": "Mechanosensing", "start": 25, "...	[]
Caregiver satisfaction with paediatric HIV treatment and care in Nigeria and equity implications for children living with HIV Caregiver satisfaction has the potential to promote equity for children living with HIV, by influencing health-seeking behaviour. We measured dimensions of caregiver satisfaction with paediatric...	{ "entities": { "group": [ { "text": "Caregiver", "start": 0, "end": 9 }, { "text": "children", "start": 101, "end": 109 }, { "text": "Caregiver", "start": 126, "end": 135 }, { "text": "childr...	[]
Eliminating Cancer Stem Cells in CML with Combination Transcriptional Therapy Leukemia stem cells (LSCs) are resistant to current therapies used to treat chronic myeloid leukemia (CML). Abraham et al. (2016) have identified a molecular network critical for CML LSC survival and propose that simultaneously targeting two ...	{ "entities": { "cells and their components": [ { "text": "Cancer Stem Cells", "start": 12, "end": 29 }, { "text": "stem cells", "start": 87, "end": 97 }, { "text": "LSCs)", "start": 99, "end": 104 }, ...	[]
Energy Expenditure and Intensity of Classroom Physical Activity in Elementary School Children There is limited data regarding objectively measured energy cost and intensity of classroom instruction. Therefore, the purpose of current study was to objectively measure energy cost and subsequently calculate MET values usin...	{ "entities": { "phenotype": [ { "text": "Energy Expenditure", "start": 0, "end": 18 }, { "text": "energy expenditure", "start": 455, "end": 473 }, { "text": "EE)", "start": 475, "end": 478 }, { ...	[]
Liver - specific mono-unsaturated fatty acid synthase-1 inhibitor for anti-hepatitis C treatment Recently, direct antiviral agents against hepatitis C virus (HCV) infection have been developed as highly effective anti-HCV drugs. However, the appearance of resistant viruses against direct anti-viral agents is an unsolve...	{ "entities": { "anatomical structure": [ { "text": "Liver", "start": 0, "end": 5 }, { "text": "eyes", "start": 1007, "end": 1011 }, { "text": "skin.", "start": 1016, "end": 1021 }, { "text": ...	[]
Relation of Left Ventricular Mass and Infarct Size in Anterior Wall ST-Segment Elevation Acute Myocardial Infarction (from the EMBRACE STEMI Clinical Trial) Biomarker measures of infarct size and myocardial salvage index (MSI) are important surrogate measures of clinical outcomes after a myocardial infarction. However,...	{ "entities": { "phenotype": [ { "text": "Left Ventricular Mass", "start": 12, "end": 33 }, { "text": "Size", "start": 46, "end": 50 }, { "text": "Biomarker", "start": 157, "end": 166 }, { "te...	[]
Hard ticks (Acari: Ixodidae) of livestock in Nicaragua, with notes about distribution We document the species of ticks that parasitize livestock in Nicaragua. The study was based on tick collection on cattle and horses from 437 farms in nine departments. Of 4841 animals examined (4481 cows and 360 horses), 3299 were pa...	{ "entities": { "organism": [ { "text": "Hard ticks", "start": 0, "end": 10 }, { "text": "Acari: Ixodidae)", "start": 12, "end": 28 }, { "text": "livestock", "start": 32, "end": 41 }, { "text"...	[]
Crocetin improves the quality of in vitro - produced bovine embryos: Implications for blastocyst development, cryotolerance, and apoptosis The aim of this work was to assess the effect of supplementation of bovine culture medium with the natural antioxidant crocetin on in vitro blastocyst development and quality. This ...	{ "entities": { "chemicals": [ { "text": "Crocetin", "start": 0, "end": 8 }, { "text": "antioxidant", "start": 246, "end": 257 }, { "text": "crocetin", "start": 258, "end": 266 }, { "text": "c...	[]
Parkinson subtype -specific Granger-causal coupling and coherence frequency in the subthalamic area Previous work on Parkinson's disease (PD) has indicated a predominantly afferent coupling between affected arm muscle activity and electrophysiological activity within the subthalamic nucleus (STN). So far, no informatio...	{ "entities": { "disorder": [ { "text": "Parkinson", "start": 0, "end": 9 }, { "text": "Parkinson's disease", "start": 117, "end": 136 }, { "text": "PD)", "start": 138, "end": 141 }, { "text":...	[]
Incidence and growth of Salmonella enterica on the peel and pulp of avocado (Persea americana) and custard apple (Annona squamosa) The aim of this study was to assess the incidence and to estimate the growth kinetic parameters (maximum growth rate, μ; lag time, λ; and maximum population, κ) of Salmonella on the peel an...	{ "entities": { "function": [ { "text": "growth", "start": 14, "end": 20 }, { "text": "growth", "start": 866, "end": 872 }, { "text": "growth", "start": 1080, "end": 1086 }, { "text": "growth"...	[]
Photocatalytic and antibacterial response of biosynthesized gold nanoparticles Increase in the bacterial resistance to available antibiotics and water contamination by different toxic organic dyes are both severe problems throughout the world. To overcome these concerns, new methodologies including synthesis of nontoxi...	{ "entities": { "function": [ { "text": "Photocatalytic and antibacterial response", "start": 0, "end": 41 }, { "text": "bacterial resistance", "start": 95, "end": 115 }, { "text": "growth of microorganisms", "start": 42...	[]
Ictal unilateral blinking is an unreliable lateralizing sign in tuberous sclerosis complex Ictal unilateral blinking is an uncommon but reportedly reliable lateralizing sign, indicating an ipsilateral seizure focus. We aimed to determine its lateralizing utility in patients with tuberous sclerosis complex (TSC). We rev...	{ "entities": { "phenotype": [ { "text": "Ictal", "start": 0, "end": 5 }, { "text": "unilateral", "start": 6, "end": 16 }, { "text": "lateralizing sign", "start": 43, "end": 60 }, { "text": "I...	[]
Assessment the Exposure Level of Rare Earth Elements in Workers Producing Cerium, Lanthanum Oxide Ultrafine and Nanoparticles In order to assess occupational exposure level of 15 rare earth elements (REEs) and identify the associated influence, we used inductively coupled plasma mass spectrometry (ICP-MS) based on clos...	{ "entities": { "activity": [ { "text": "Assessment", "start": 0, "end": 10 }, { "text": "Producing", "start": 64, "end": 73 }, { "text": "inductively coupled plasma mass spectrometry", "start": 253, "end": 297 ...	[]
A remarkable new species of Eutrichopoda Townsend , 1908 (Diptera: Tachinidae: Phasiinae) A new Tachinidae species, Eutrichopoda flavipenna sp. nov. (Diptera: Tachinidae: Phasiinae), from Brazil and Paraguay is described and illustrated by photographs and line drawings. The remarkable yellow, feather-like setae on the ...	{ "entities": { "organism": [ { "text": "Eutrichopoda Townsend ,", "start": 28, "end": 51 }, { "text": "(Diptera:", "start": 57, "end": 66 }, { "text": "Tachinidae:", "start": 67, "end": 78 }, { ...	[]
Two known and one new species of Draconematidae and Epsilonematida (Nematoda, Desmodorida) from the White Sea, North Russia Morphological descriptions of three " walking nematode " species found for the first time in the White Sea are presented. Draconema ophicephalum (Claparède , 1863) (Draconematidae) and Epsilonema ...	{ "entities": { "organism": [ { "text": "Draconematidae", "start": 33, "end": 47 }, { "text": "Epsilonematida", "start": 52, "end": 66 }, { "text": "Nematoda,", "start": 68, "end": 77 }, { "te...	[]
Differential effects of crude oil on denitrification and anammox, and the impact on N2O production Denitrification and anammox are key processes for reducing the external nitrogen loads delivered to coastal ecosystems, and these processes can be affected by pollutants. In this study, we investigated the effect of crude...	{ "entities": { "chemicals": [ { "text": "crude oil", "start": 24, "end": 33 }, { "text": "N2O", "start": 84, "end": 87 }, { "text": "nitrogen", "start": 171, "end": 179 }, { "text": "pollutan...	[]
Lateral hypothalamus orexinergic system modulates the stress effect on pentylenetetrazol induced seizures through corticotropin releasing hormone receptor type 1 Stress is a trigger factor for seizure initiation which activates hypothalamic pituitary adrenal (HPA) axis as well other brain areas. In this respect, cortic...	{ "entities": { "anatomical structure": [ { "text": "Lateral hypothalamus orexinergic system", "start": 0, "end": 39 }, { "text": "hypothalamic pituitary adrenal (HPA) axis", "start": 228, "end": 269 }, { "text": "brain", ...	[]
Shining the light on the dark side of medical leadership - a qualitative study in Australia Purpose The paper aims to explore the beliefs of doctors in leadership roles of the concept of " the dark side ", using data collected from interviews carried out with 45 doctors in medical leadership roles across Australia. The...	{ "entities": { "activity": [ { "text": "leadership", "start": 46, "end": 56 }, { "text": "leadership", "start": 152, "end": 162 }, { "text": "interviews", "start": 232, "end": 242 }, { "text"...	[]
A parametric ribcage geometry model accounting for variations among the adult population The objective of this study is to develop a parametric ribcage model that can account for morphological variations among the adult population. Ribcage geometries, including 12 pair of ribs, sternum, and thoracic spine, were collect...	{ "entities": { "anatomical structure": [ { "text": "ribcage", "start": 13, "end": 20 }, { "text": "ribcage", "start": 144, "end": 151 }, { "text": "Ribcage", "start": 232, "end": 239 }, { "te...	[]
Hyaluronan Depolymerization by Megakaryocyte Hyaluronidase-2 Is Required for Thrombopoiesis Hyaluronan is the predominant glycosaminoglycan component of the extracellular matrix with an emerging role in hematopoiesis. Modulation of hyaluronan polymer size is responsible for its control over cellular functions, and the ...	{ "entities": { "chemicals": [ { "text": "Hyaluronan", "start": 0, "end": 10 }, { "text": "Hyaluronan", "start": 92, "end": 102 }, { "text": "glycosaminoglycan component", "start": 122, "end": 149 }, ...	[]
Vitamin D serum level is associated with Child-Pugh score and metabolic enzyme imbalances, but not viral load in chronic hepatitis B patients Vitamin D deficiency is common in patients with chronic liver diseases. However, vitamin D status in persons with chronic hepatitis B virus (HBV) infection is not consistently re...	{ "entities": { "chemicals": [ { "text": "Vitamin D", "start": 0, "end": 9 }, { "text": "vitamin D", "start": 223, "end": 232 }, { "text": "vitamin D", "start": 377, "end": 386 }, { "text": "2...	[]
359 Delayed Treatment of Ruptured Arteriovenous Malformations: Is It Ok to Wait? Emergent surgery on a ruptured brain arteriovenous malformation (AVM) is indicated for a large hematoma in an acutely deteriorating patient. The majority of ruptured AVMs, however, present in clinically stable patients with neurological de...	{ "entities": { "medical procedure": [ { "text": "Delayed Treatment", "start": 4, "end": 21 }, { "text": "surgery", "start": 90, "end": 97 }, { "text": "treatment", "start": 377, "end": 386 }, { ...	[]
Prescribing Patterns in Outpatient Clinics of Township Hospitals in China: A Comparative Study before and after the 2009 Health System Reform Objective: China introduced a series of health reforms in 2009, including a national essential medicines policy and a medical insurance system for primary care institutions. This...	{ "entities": { "intellectual property": [ { "text": "Prescribing Patterns", "start": 0, "end": 20 }, { "text": "Comparative Study", "start": 77, "end": 94 }, { "text": "study", "start": 321, "end": 326 }, ...	[]
Neural activity promotes long-distance, target - specific regeneration of adult retinal axons Axons in the mammalian CNS fail to regenerate after injury. Here we show that if the activity of mouse retinal ganglion cells (RGCs) is increased by visual stimulation or using chemogenetics, their axons regenerate. We also sh...	{ "entities": { "function": [ { "text": "Neural activity", "start": 0, "end": 15 }, { "text": "regeneration", "start": 58, "end": 70 }, { "text": "activity", "start": 179, "end": 187 }, { "tex...	[]
Expression of WNT10A Gene in Oral Squamous Cell Carcinoma Oral squamous cell carcinoma (OSCC) constitutes the most frequent malignant tumour of the oral cavity. Considering the significant roles the Wnt family plays in physiological and pathological events, this study aims to investigate WNT10A gene expression in OSCC....	{ "entities": { "function": [ { "text": "Expression", "start": 0, "end": 10 }, { "text": "physiological", "start": 219, "end": 232 }, { "text": "pathological events,", "start": 237, "end": 257 }, { ...	[]
Erlotinib plus gemcitabine versus gemcitabine for pancreatic cancer: real - world analysis of Korean national database A randomized clinical trial has found that the addition of erlotinib to gemcitabine (GEM - E) for pancreatic cancer led to a modest increase in survival. The aim of this national population - based ret...	{ "entities": { "clinical drug": [ { "text": "Erlotinib", "start": 0, "end": 9 }, { "text": "gemcitabine", "start": 15, "end": 26 }, { "text": "gemcitabine", "start": 34, "end": 45 }, { "text"...	[]
Predicting Risk of Suicide Attempt Using History of Physical Illnesses From Electronic Medical Records Although physical illnesses, routinely documented in electronic medical records (EMR), have been found to be a contributing factor to suicides, no automated systems use this information to predict suicide risk. The ai...	{ "entities": { "phenotype": [ { "text": "Risk", "start": 11, "end": 15 }, { "text": "Attempt", "start": 27, "end": 34 }, { "text": "contributing factor", "start": 214, "end": 233 }, { "text":...	[]
Development of a Novel Quantitative Structure-Activity Relationship Model to Accurately Predict Pulmonary Absorption and Replace Routine Use of the Isolated Perfused Respiring Rat Lung Model We developed and tested a novel Quantitative Structure-Activity Relationship (QSAR) model to better understand the physicochemica...	{ "entities": { "activity": [ { "text": "Development", "start": 0, "end": 11 }, { "text": "ranking", "start": 1317, "end": 1324 }, { "text": "classifying", "start": 1329, "end": 1340 }, { "tex...	[]
Matrix solid-phase dispersion combined to liquid chromatography-tandem mass spectrometry for the determination of paraben preservatives in mollusks A method for the extraction and determination of seven parabens, esters of 4-hydroxybenzoic acid, widely used as preservatives in personal care products, pharmaceuticals, e...	{ "entities": { "activity": [ { "text": "Matrix solid-phase dispersion", "start": 0, "end": 29 }, { "text": "liquid chromatography-tandem mass spectrometry", "start": 42, "end": 88 }, { "text": "determination", "start": ...	[]
The EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay: Historical control data and proof of principle studies for mechanistic assay adaptations The in vitro human reconstructed skin micronucleus (RSMN) assay in EpiDerm™ is a promising novel animal alternative for evaluating genotoxicity of topically applie...	{ "entities": { "product": [ { "text": "EpiDerm™", "start": 4, "end": 12 }, { "text": "EpiDerm™", "start": 224, "end": 232 } ], "activity": [ { "text": "3D human reconstructed skin micronucleus (RSMN) assay:", "s...	[]
Two-stage reconstructive overlapping stent LEO+ and SILK for treatment of intracranial circumferential fusiform aneurysms in the posterior circulation Intracranial circumferential fusiform aneurysms of the posterior circulation involving arterial branches or perforating vessels are difficult to treat. This article show...	{ "entities": { "product": [ { "text": "overlapping stent", "start": 25, "end": 42 }, { "text": "LEO+", "start": 43, "end": 47 }, { "text": "SILK", "start": 52, "end": 56 }, { "text": "telesco...	[]
Wnt-5a / Frizzled9 receptor signaling through the Gαo / Gβγ complex regulates dendritic spine formation Wnt ligands play crucial roles in the development and regulation of synapse structure and function. Specifically, Wnt-5a acts as a secreted growth factor that regulates dendritic spine formation in rodent hippocampal...	{ "entities": { "gene and gene products": [ { "text": "Wnt-5a", "start": 0, "end": 6 }, { "text": "Frizzled9", "start": 9, "end": 18 }, { "text": "receptor", "start": 19, "end": 27 }, { "text"...	[]
A Delayed Diagnosis of Chronic Mesenteric Ischaemia: The Role of Clinicians' Cognitive Errors Chronic diarrhoeal illnesses with nausea and weight loss are a common indication for gastroenterology review. While many such cases have intra-luminal aetiologies, such as inflammatory bowel disease, coeliac disease or other m...	{ "entities": { "medical procedure": [ { "text": "Delayed Diagnosis", "start": 2, "end": 19 }, { "text": "delayed diagnosis", "start": 509, "end": 526 }, { "text": "treatment", "start": 789, "end": 798 }, ...	[]
Evaluation of Choroidal Thickness in Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma Purpose. To compare the macular and peripapillary choroidal thickness in eyes with pseudoexfoliation (PEX) syndrome and PEX glaucoma with the normal eyes of healthy controls. Materials and Methods. In this prosp...	{ "entities": { "activity": [ { "text": "Evaluation", "start": 0, "end": 10 }, { "text": "lower", "start": 881, "end": 886 }, { "text": "compared", "start": 887, "end": 895 } ], "anatomical structur...	[]
Polysaccharide - Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage We have previously demonstrated that experimental pneumococcal carriage enhances immunity and protects healthy adults against carriage reacquisition after rechallenge with a homologous strain. To investigate the...	{ "entities": { "chemicals": [ { "text": "Polysaccharide", "start": 0, "end": 14 }, { "text": "polysaccharide", "start": 373, "end": 387 }, { "text": "PS)", "start": 389, "end": 392 }, { "text...	[]
A Retrospective Review of Forensic Odontology Reports Written by the Joint POW/MIA Accounting Command Central Identification Laboratory for Remains Identified from the Korean War As of August 2014, the Joint POW/MIA Accounting Command has identified the remains of 1980 previously unknown U.S. service members; 280 were ...	{ "entities": { "intellectual property": [ { "text": "Review", "start": 16, "end": 22 }, { "text": "Forensic Odontology Reports", "start": 26, "end": 53 }, { "text": "accuracy", "start": 358, "end": 366 }, ...	[]
Predicting Sources of Dissolved Organic Nitrogen to an Estuary from an Agro - Urban Coastal Watershed Dissolved organic nitrogen (DON) is the nitrogen (N) -containing component of dissolved organic matter (DOM) and in aquatic ecosystems is part of the biologically-reactive nitrogen pool that can degrade water quality i...	{ "entities": { "chemicals": [ { "text": "Dissolved Organic Nitrogen", "start": 22, "end": 48 }, { "text": "Dissolved organic nitrogen", "start": 102, "end": 128 }, { "text": "DON)", "start": 130, "end": 134 ...	[]
Clinical Features and Complications of the HLA-B27 -associated Acute Anterior Uveitis: A Metanalysis In this article, we report a literature-based metanalysis we have conducted to outline the clinical features of the HLA-B27 Acute Anterior Uveitis (AAU). The examined material was based on observational studies in which...	{ "entities": { "phenotype": [ { "text": "Clinical Features", "start": 0, "end": 17 }, { "text": "Complications", "start": 22, "end": 35 }, { "text": "clinical features", "start": 192, "end": 209 }, {...	[]

Weed seed inactivation in soil mesocosms via biosolarization with mature compost and tomato processing waste amendments Biosolarization is a fumigation alternative that combines passive solar heating with amendment-driven soil microbial activity to temporarily create antagonistic soil conditions, such as elevated tempe...

{ "entities": { "organism": [ { "text": "Weed", "start": 0, "end": 4 }, { "text": "seed", "start": 5, "end": 9 }, { "text": "tomato", "start": 85, "end": 91 }, { "text": "weed", "start...

[]

Phenotypic and genetic heterogeneity of tumor tissue and circulating tumor cells in patients with metastatic castration-resistant prostate cancer: A report from the PETRUS prospective study Molecular characterization of cancer samples is hampered by tumor tissue availability in metastatic castration-resistant prostate ...

{ "entities": { "phenotype": [ { "text": "genetic heterogeneity", "start": 15, "end": 36 }, { "text": "metastatic", "start": 771, "end": 781 }, { "text": "primary tumors,", "start": 795, "end": 810 }, ...

[]

Impact of Soil Salinity on the Structure of the Bacterial Endophytic Community Identified from the Roots of Caliph Medic (Medicago truncatula) In addition to being a forage crop, Caliph medic (Medicago truncatula) is also a model legume plant and is used for research focusing on the molecular characterization of the in...

{ "entities": { "organism": [ { "text": "Bacterial", "start": 48, "end": 57 }, { "text": "Roots", "start": 99, "end": 104 }, { "text": "Caliph Medic", "start": 108, "end": 120 }, { "text": "Me...

[]

Role of the Membrane for Mechanosensing by Tethered Channels Biologically important membrane channels are gated by force at attached tethers. Here, we generically characterize the nontrivial interplay of force, membrane tension, and channel deformations that can affect gating. A central finding is that minute conical c...

{ "entities": { "cells and their components": [ { "text": "Membrane", "start": 12, "end": 20 }, { "text": "tethers.", "start": 133, "end": 141 } ], "function": [ { "text": "Mechanosensing", "start": 25, "...

[]

Caregiver satisfaction with paediatric HIV treatment and care in Nigeria and equity implications for children living with HIV Caregiver satisfaction has the potential to promote equity for children living with HIV, by influencing health-seeking behaviour. We measured dimensions of caregiver satisfaction with paediatric...

{ "entities": { "group": [ { "text": "Caregiver", "start": 0, "end": 9 }, { "text": "children", "start": 101, "end": 109 }, { "text": "Caregiver", "start": 126, "end": 135 }, { "text": "childr...

[]

Eliminating Cancer Stem Cells in CML with Combination Transcriptional Therapy Leukemia stem cells (LSCs) are resistant to current therapies used to treat chronic myeloid leukemia (CML). Abraham et al. (2016) have identified a molecular network critical for CML LSC survival and propose that simultaneously targeting two ...

{ "entities": { "cells and their components": [ { "text": "Cancer Stem Cells", "start": 12, "end": 29 }, { "text": "stem cells", "start": 87, "end": 97 }, { "text": "LSCs)", "start": 99, "end": 104 }, ...

[]

Energy Expenditure and Intensity of Classroom Physical Activity in Elementary School Children There is limited data regarding objectively measured energy cost and intensity of classroom instruction. Therefore, the purpose of current study was to objectively measure energy cost and subsequently calculate MET values usin...

{ "entities": { "phenotype": [ { "text": "Energy Expenditure", "start": 0, "end": 18 }, { "text": "energy expenditure", "start": 455, "end": 473 }, { "text": "EE)", "start": 475, "end": 478 }, { ...

[]

Liver - specific mono-unsaturated fatty acid synthase-1 inhibitor for anti-hepatitis C treatment Recently, direct antiviral agents against hepatitis C virus (HCV) infection have been developed as highly effective anti-HCV drugs. However, the appearance of resistant viruses against direct anti-viral agents is an unsolve...

{ "entities": { "anatomical structure": [ { "text": "Liver", "start": 0, "end": 5 }, { "text": "eyes", "start": 1007, "end": 1011 }, { "text": "skin.", "start": 1016, "end": 1021 }, { "text": ...

[]

Relation of Left Ventricular Mass and Infarct Size in Anterior Wall ST-Segment Elevation Acute Myocardial Infarction (from the EMBRACE STEMI Clinical Trial) Biomarker measures of infarct size and myocardial salvage index (MSI) are important surrogate measures of clinical outcomes after a myocardial infarction. However,...

{ "entities": { "phenotype": [ { "text": "Left Ventricular Mass", "start": 12, "end": 33 }, { "text": "Size", "start": 46, "end": 50 }, { "text": "Biomarker", "start": 157, "end": 166 }, { "te...

[]

Hard ticks (Acari: Ixodidae) of livestock in Nicaragua, with notes about distribution We document the species of ticks that parasitize livestock in Nicaragua. The study was based on tick collection on cattle and horses from 437 farms in nine departments. Of 4841 animals examined (4481 cows and 360 horses), 3299 were pa...

{ "entities": { "organism": [ { "text": "Hard ticks", "start": 0, "end": 10 }, { "text": "Acari: Ixodidae)", "start": 12, "end": 28 }, { "text": "livestock", "start": 32, "end": 41 }, { "text"...

[]

Crocetin improves the quality of in vitro - produced bovine embryos: Implications for blastocyst development, cryotolerance, and apoptosis The aim of this work was to assess the effect of supplementation of bovine culture medium with the natural antioxidant crocetin on in vitro blastocyst development and quality. This ...

{ "entities": { "chemicals": [ { "text": "Crocetin", "start": 0, "end": 8 }, { "text": "antioxidant", "start": 246, "end": 257 }, { "text": "crocetin", "start": 258, "end": 266 }, { "text": "c...

[]

Parkinson subtype -specific Granger-causal coupling and coherence frequency in the subthalamic area Previous work on Parkinson's disease (PD) has indicated a predominantly afferent coupling between affected arm muscle activity and electrophysiological activity within the subthalamic nucleus (STN). So far, no informatio...

{ "entities": { "disorder": [ { "text": "Parkinson", "start": 0, "end": 9 }, { "text": "Parkinson's disease", "start": 117, "end": 136 }, { "text": "PD)", "start": 138, "end": 141 }, { "text":...

[]

Incidence and growth of Salmonella enterica on the peel and pulp of avocado (Persea americana) and custard apple (Annona squamosa) The aim of this study was to assess the incidence and to estimate the growth kinetic parameters (maximum growth rate, μ; lag time, λ; and maximum population, κ) of Salmonella on the peel an...

{ "entities": { "function": [ { "text": "growth", "start": 14, "end": 20 }, { "text": "growth", "start": 866, "end": 872 }, { "text": "growth", "start": 1080, "end": 1086 }, { "text": "growth"...

[]

Photocatalytic and antibacterial response of biosynthesized gold nanoparticles Increase in the bacterial resistance to available antibiotics and water contamination by different toxic organic dyes are both severe problems throughout the world. To overcome these concerns, new methodologies including synthesis of nontoxi...

{ "entities": { "function": [ { "text": "Photocatalytic and antibacterial response", "start": 0, "end": 41 }, { "text": "bacterial resistance", "start": 95, "end": 115 }, { "text": "growth of microorganisms", "start": 42...

[]

Ictal unilateral blinking is an unreliable lateralizing sign in tuberous sclerosis complex Ictal unilateral blinking is an uncommon but reportedly reliable lateralizing sign, indicating an ipsilateral seizure focus. We aimed to determine its lateralizing utility in patients with tuberous sclerosis complex (TSC). We rev...

{ "entities": { "phenotype": [ { "text": "Ictal", "start": 0, "end": 5 }, { "text": "unilateral", "start": 6, "end": 16 }, { "text": "lateralizing sign", "start": 43, "end": 60 }, { "text": "I...

[]

Assessment the Exposure Level of Rare Earth Elements in Workers Producing Cerium, Lanthanum Oxide Ultrafine and Nanoparticles In order to assess occupational exposure level of 15 rare earth elements (REEs) and identify the associated influence, we used inductively coupled plasma mass spectrometry (ICP-MS) based on clos...

{ "entities": { "activity": [ { "text": "Assessment", "start": 0, "end": 10 }, { "text": "Producing", "start": 64, "end": 73 }, { "text": "inductively coupled plasma mass spectrometry", "start": 253, "end": 297 ...

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A remarkable new species of Eutrichopoda Townsend , 1908 (Diptera: Tachinidae: Phasiinae) A new Tachinidae species, Eutrichopoda flavipenna sp. nov. (Diptera: Tachinidae: Phasiinae), from Brazil and Paraguay is described and illustrated by photographs and line drawings. The remarkable yellow, feather-like setae on the ...

{ "entities": { "organism": [ { "text": "Eutrichopoda Townsend ,", "start": 28, "end": 51 }, { "text": "(Diptera:", "start": 57, "end": 66 }, { "text": "Tachinidae:", "start": 67, "end": 78 }, { ...

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Two known and one new species of Draconematidae and Epsilonematida (Nematoda, Desmodorida) from the White Sea, North Russia Morphological descriptions of three " walking nematode " species found for the first time in the White Sea are presented. Draconema ophicephalum (Claparède , 1863) (Draconematidae) and Epsilonema ...

{ "entities": { "organism": [ { "text": "Draconematidae", "start": 33, "end": 47 }, { "text": "Epsilonematida", "start": 52, "end": 66 }, { "text": "Nematoda,", "start": 68, "end": 77 }, { "te...

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Differential effects of crude oil on denitrification and anammox, and the impact on N2O production Denitrification and anammox are key processes for reducing the external nitrogen loads delivered to coastal ecosystems, and these processes can be affected by pollutants. In this study, we investigated the effect of crude...

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Lateral hypothalamus orexinergic system modulates the stress effect on pentylenetetrazol induced seizures through corticotropin releasing hormone receptor type 1 Stress is a trigger factor for seizure initiation which activates hypothalamic pituitary adrenal (HPA) axis as well other brain areas. In this respect, cortic...

{ "entities": { "anatomical structure": [ { "text": "Lateral hypothalamus orexinergic system", "start": 0, "end": 39 }, { "text": "hypothalamic pituitary adrenal (HPA) axis", "start": 228, "end": 269 }, { "text": "brain", ...

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Shining the light on the dark side of medical leadership - a qualitative study in Australia Purpose The paper aims to explore the beliefs of doctors in leadership roles of the concept of " the dark side ", using data collected from interviews carried out with 45 doctors in medical leadership roles across Australia. The...

{ "entities": { "activity": [ { "text": "leadership", "start": 46, "end": 56 }, { "text": "leadership", "start": 152, "end": 162 }, { "text": "interviews", "start": 232, "end": 242 }, { "text"...

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A parametric ribcage geometry model accounting for variations among the adult population The objective of this study is to develop a parametric ribcage model that can account for morphological variations among the adult population. Ribcage geometries, including 12 pair of ribs, sternum, and thoracic spine, were collect...

{ "entities": { "anatomical structure": [ { "text": "ribcage", "start": 13, "end": 20 }, { "text": "ribcage", "start": 144, "end": 151 }, { "text": "Ribcage", "start": 232, "end": 239 }, { "te...

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Hyaluronan Depolymerization by Megakaryocyte Hyaluronidase-2 Is Required for Thrombopoiesis Hyaluronan is the predominant glycosaminoglycan component of the extracellular matrix with an emerging role in hematopoiesis. Modulation of hyaluronan polymer size is responsible for its control over cellular functions, and the ...

{ "entities": { "chemicals": [ { "text": "Hyaluronan", "start": 0, "end": 10 }, { "text": "Hyaluronan", "start": 92, "end": 102 }, { "text": "glycosaminoglycan component", "start": 122, "end": 149 }, ...

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Vitamin D serum level is associated with Child-Pugh score and metabolic enzyme imbalances, but not viral load in chronic hepatitis B patients Vitamin D deficiency is common in patients with chronic liver diseases. However, vitamin D status in persons with chronic hepatitis B virus (HBV) infection is not consistently re...

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359 Delayed Treatment of Ruptured Arteriovenous Malformations: Is It Ok to Wait? Emergent surgery on a ruptured brain arteriovenous malformation (AVM) is indicated for a large hematoma in an acutely deteriorating patient. The majority of ruptured AVMs, however, present in clinically stable patients with neurological de...

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Prescribing Patterns in Outpatient Clinics of Township Hospitals in China: A Comparative Study before and after the 2009 Health System Reform Objective: China introduced a series of health reforms in 2009, including a national essential medicines policy and a medical insurance system for primary care institutions. This...

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Neural activity promotes long-distance, target - specific regeneration of adult retinal axons Axons in the mammalian CNS fail to regenerate after injury. Here we show that if the activity of mouse retinal ganglion cells (RGCs) is increased by visual stimulation or using chemogenetics, their axons regenerate. We also sh...

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Expression of WNT10A Gene in Oral Squamous Cell Carcinoma Oral squamous cell carcinoma (OSCC) constitutes the most frequent malignant tumour of the oral cavity. Considering the significant roles the Wnt family plays in physiological and pathological events, this study aims to investigate WNT10A gene expression in OSCC....

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Erlotinib plus gemcitabine versus gemcitabine for pancreatic cancer: real - world analysis of Korean national database A randomized clinical trial has found that the addition of erlotinib to gemcitabine (GEM - E) for pancreatic cancer led to a modest increase in survival. The aim of this national population - based ret...

{ "entities": { "clinical drug": [ { "text": "Erlotinib", "start": 0, "end": 9 }, { "text": "gemcitabine", "start": 15, "end": 26 }, { "text": "gemcitabine", "start": 34, "end": 45 }, { "text"...

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Predicting Risk of Suicide Attempt Using History of Physical Illnesses From Electronic Medical Records Although physical illnesses, routinely documented in electronic medical records (EMR), have been found to be a contributing factor to suicides, no automated systems use this information to predict suicide risk. The ai...

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Development of a Novel Quantitative Structure-Activity Relationship Model to Accurately Predict Pulmonary Absorption and Replace Routine Use of the Isolated Perfused Respiring Rat Lung Model We developed and tested a novel Quantitative Structure-Activity Relationship (QSAR) model to better understand the physicochemica...

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Matrix solid-phase dispersion combined to liquid chromatography-tandem mass spectrometry for the determination of paraben preservatives in mollusks A method for the extraction and determination of seven parabens, esters of 4-hydroxybenzoic acid, widely used as preservatives in personal care products, pharmaceuticals, e...

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The EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay: Historical control data and proof of principle studies for mechanistic assay adaptations The in vitro human reconstructed skin micronucleus (RSMN) assay in EpiDerm™ is a promising novel animal alternative for evaluating genotoxicity of topically applie...

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Two-stage reconstructive overlapping stent LEO+ and SILK for treatment of intracranial circumferential fusiform aneurysms in the posterior circulation Intracranial circumferential fusiform aneurysms of the posterior circulation involving arterial branches or perforating vessels are difficult to treat. This article show...

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Wnt-5a / Frizzled9 receptor signaling through the Gαo / Gβγ complex regulates dendritic spine formation Wnt ligands play crucial roles in the development and regulation of synapse structure and function. Specifically, Wnt-5a acts as a secreted growth factor that regulates dendritic spine formation in rodent hippocampal...

{ "entities": { "gene and gene products": [ { "text": "Wnt-5a", "start": 0, "end": 6 }, { "text": "Frizzled9", "start": 9, "end": 18 }, { "text": "receptor", "start": 19, "end": 27 }, { "text"...

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A Delayed Diagnosis of Chronic Mesenteric Ischaemia: The Role of Clinicians' Cognitive Errors Chronic diarrhoeal illnesses with nausea and weight loss are a common indication for gastroenterology review. While many such cases have intra-luminal aetiologies, such as inflammatory bowel disease, coeliac disease or other m...

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Evaluation of Choroidal Thickness in Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma Purpose. To compare the macular and peripapillary choroidal thickness in eyes with pseudoexfoliation (PEX) syndrome and PEX glaucoma with the normal eyes of healthy controls. Materials and Methods. In this prosp...

{ "entities": { "activity": [ { "text": "Evaluation", "start": 0, "end": 10 }, { "text": "lower", "start": 881, "end": 886 }, { "text": "compared", "start": 887, "end": 895 } ], "anatomical structur...

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Polysaccharide - Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage We have previously demonstrated that experimental pneumococcal carriage enhances immunity and protects healthy adults against carriage reacquisition after rechallenge with a homologous strain. To investigate the...

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A Retrospective Review of Forensic Odontology Reports Written by the Joint POW/MIA Accounting Command Central Identification Laboratory for Remains Identified from the Korean War As of August 2014, the Joint POW/MIA Accounting Command has identified the remains of 1980 previously unknown U.S. service members; 280 were ...

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Predicting Sources of Dissolved Organic Nitrogen to an Estuary from an Agro - Urban Coastal Watershed Dissolved organic nitrogen (DON) is the nitrogen (N) -containing component of dissolved organic matter (DOM) and in aquatic ecosystems is part of the biologically-reactive nitrogen pool that can degrade water quality i...

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Clinical Features and Complications of the HLA-B27 -associated Acute Anterior Uveitis: A Metanalysis In this article, we report a literature-based metanalysis we have conducted to outline the clinical features of the HLA-B27 Acute Anterior Uveitis (AAU). The examined material was based on observational studies in which...

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