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Adolescent Female, 6-month history of persistent papules, pustules, and comedones on the face, chest, and upper back. Denies fever, weight loss, or other systemic symptoms. On examination: Multiple open and closed comedones, inflammatory papules, and pustules on the face, chest, and upper back, with no signs of scarr...
Acne**
Acne Adult Male, 2-year history of recurrent nodules and cysts on the face and back. Denies fever, weight loss, or other systemic symptoms. On examination: Multiple inflammatory nodules and cysts on the face and back, with scarring and post-inflammatory hyperpigmentation. Symptoms are aggravated by sweating and cer...
Acne**
Adult Female, 6-month history of progressive hearing loss and tinnitus in the left ear. Denies vertigo, facial weakness, or numbness. On examination: Decreased hearing acuity and positive Rinne and Weber tests lateralizing to the left, with no facial nerve palsy or other cranial nerve deficits. Symptoms are aggrava...
Acoustic Neuroma**
Acoustic Neuroma Adult Male, 1-year history of gradual hearing loss, balance issues, and occasional unsteadiness. Denies tinnitus, vertigo, or facial weakness. On examination: Asymmetric hearing loss in the right ear, positive Romberg test, with no nystagmus or other neurological deficits. Symptoms are relieved by...
Acoustic Neuroma**
Adult Male, 3-year history of gradual enlargement of hands and feet, coarsening of facial features, excessive sweating, and fatigue. Denies visual changes, headaches, or galactorrhea. On examination: prominent supraorbital ridges, enlarged nose and lips, macroglossia, and prognathism, with no visual field defects or ...
Acromegaly**
Acromegaly Adult Female, 5-year history of progressive enlargement of extremities, increased ring and shoe sizes, deepening of voice, and irregular menstrual cycles. Denies visual disturbances, headaches, or galactorrhea. On examination: coarse facial features, enlarged hands and feet, increased skin tags, and mild h...
Acromegaly**
Adult Male, 24-hour history of decreased urine output and fatigue. Denies fever, rash, or abdominal pain. On examination: mild peripheral edema, with no costovertebral angle tenderness. Symptoms are aggravated by fluid restriction. Risk factors include recent gastroenteritis with severe vomiting and diarrhea, his...
Acute Kidney Injury**
Acute Kidney Injury Adolescent Female, 3-day history of dark urine, fatigue, and mild shortness of breath. Denies fever, changes in bowel habits, or flank pain. On examination: mild pedal edema, pallor, with no costovertebral angle tenderness. Symptoms are aggravated by exertion. Risk factors include recent stre...
Acute Kidney Injury**
Adult Female, 6-month history of progressive fatigue, weight loss, decreased appetite, and salt cravings. Denies fever, night sweats, or changes in bowel habits. On examination: Hypotension (90/60 mmHg), hyperpigmentation of the skin and mucous membranes, with no lymphadenopathy or hepatosplenomegaly. Symptoms are aggr...
Addison's Disease**
Addison's Disease Adolescent Male, 3-month history of chronic fatigue, dizziness, muscle weakness, and increased skin pigmentation. Denies abdominal pain, vomiting, or diarrhea. On examination: Orthostatic hypotension, hyperpigmentation of the buccal mucosa and palmar creases, with no signs of dehydration or organomega...
Addison's Disease**
Child Male, 3-week history of sore throat, nasal congestion, and mouth breathing. Denies cough, wheezing, or chest pain. On examination: Enlarged, inflamed adenoids visible on nasopharyngoscopy, with no exudate in the throat. Mild cervical lymphadenopathy, with no tonsillar enlargement. Symptoms are aggravated by l...
Adenoiditis**
Adenoiditis Adolescent Female, 2-month history of persistent nasal obstruction, snoring, and intermittent ear pain. Denies fever, cough, or facial swelling. On examination: Nasal obstruction, enlarged and inflamed adenoids on nasopharyngoscopy, with mild serous otitis media on otoscopy. No cervical lymphadenopathy. ...
Adenoiditis**
Adult Male, 3-week history of fever, headache, joint pain, and itching. Denies nausea, vomiting, or abdominal pain. On examination: enlarged lymph nodes in the neck, fever (38.5°C), with no signs of jaundice or hepatosplenomegaly. Symptoms are relieved by antipyretics. Risk factors include travel to rural areas i...
African Sleeping Sickness**
African Sleeping Sickness Adolescent Female, 2-month history of intermittent fever, severe headache, and progressive confusion. Denies seizures or focal neurological deficits. On examination: altered mental status, papilledema, with no focal neurological signs. Symptoms are aggravated by lack of sleep and relieved...
African Sleeping Sickness**
Adult Male, 3-month history of progressive hair loss on the scalp, characterized by multiple, round patches of complete hair loss. Denies itching, scaling, or pain. On examination: Smooth, well-demarcated patches of hair loss without scarring or erythema, with normal-appearing scalp elsewhere. Symptoms are not aggr...
Alopecia Areata**
Alopecia Areata Adolescent Female, 6-month history of diffuse hair thinning and loss, particularly noticeable in the shower and on her pillow. Denies patchy hair loss, itching, or burning. On examination: Diffuse hair thinning over the entire scalp, more prominent on the crown, with no scarring or erythema. Symptom...
Telogen Effluvium**
Adult Male, 5-year history of progressive dyspnea, chronic cough with yellowish sputum, and recurrent lower respiratory tract infections. Denies hemoptysis, chest pain, or fever. On examination: Decreased breath sounds, wheezing, and coarse crackles in the lower lung fields, with no signs of cyanosis or digital clubb...
Alpha-1 Antitrypsin Deficiency**
Alpha-1 Antitrypsin Deficiency Adolescent Female, 3-year history of mild dyspnea on exertion, occasional dry cough, and fatigue. Denies wheezing, sputum production, or recurrent infections. On examination: Mildly decreased breath sounds at the bases, with no adventitious sounds or signs of liver disease. Symptoms a...
Alpha-1 Antitrypsin Deficiency**
Child Male, 3-year history of persistent microscopic hematuria. Denies gross hematuria, dysuria, or urinary frequency. On examination: Normal blood pressure, no edema, with no costovertebral angle tenderness. Symptoms are not aggravated by exercise or activity. Risk factors include a family history of Alport Synd...
Alport Syndrome**
Alport Syndrome Adult Female, 15-year history of persistent microscopic hematuria and intermittent gross hematuria. Denies dysuria, urinary frequency, or foamy urine. On examination: Mild hypertension, no edema, with no costovertebral angle tenderness. Sensorineural hearing loss noted on audiometry. Symptoms are no...
Alport Syndrome**
Adult Female, 2-year history of progressive memory loss, confusion, and difficulty with daily tasks. Denies headaches, seizures, or recent falls. On examination: Disorientation to time and place, impaired short-term memory, with normal gait and no focal neurological deficits. Symptoms are aggravated by stress and r...
Alzheimer's Disease**
Alzheimer's Disease Adult Male, 3-year history of gradual cognitive decline, word-finding difficulties, and mood changes. Denies visual or auditory hallucinations, or motor symptoms. On examination: Impaired recent memory, visuospatial disorientation, with normal motor strength and reflexes. Symptoms are aggravated...
Alzheimer's Disease**
Child Female, 3-year history of decreased vision in the right eye. Denies eye pain, redness, or discharge. On examination: Reduced visual acuity in the right eye (20/80), normal visual acuity in the left eye (20/20), with no signs of inflammation or infection. Right eye exhibits slight strabismus. Symptoms are not ...
Amblyopia**
Amblyopia Adolescent Male, 10-year history of poor vision in the left eye. Denies headaches, eye pain, or double vision. On examination: Visual acuity of 20/100 in the left eye, 20/20 in the right eye, with no obvious structural abnormalities. Left eye shows mild anisometropia. Symptoms are not aggravated or reliev...
Amblyopia**
Adolescent Female, 6-month history of primary amenorrhea. Denies pregnancy symptoms, galactorrhea, hirsutism, and heat or cold intolerance. On examination: normal vital signs, normal secondary sexual characteristics, no turner stigmata, with no abdominal tenderness, no vaginal abnormalities. Symptoms are not aggrav...
Amenorrhea**
Amenorrhea Adult Female, 3-month history of secondary amenorrhea. Denies pregnancy symptoms, galactorrhea, hirsutism, and heat or cold intolerance. On examination: normal vital signs, normal body mass index, no signs of virilization, with no abdominal tenderness, no vaginal abnormalities. Symptoms are not aggravate...
Amenorrhea**
Adult Male, 6-month history of progressive muscle weakness and twitching in the right arm. Denies sensory changes, bowel or bladder dysfunction, or cognitive impairment. On examination: Muscle atrophy and fasciculations in the right arm, with increased tone and brisk reflexes in all limbs. Plantar response is extenso...
Amyotrophic Lateral Sclerosis (ALS)**
Amyotrophic Lateral Sclerosis (ALS) Adult Female, 8-month history of progressive difficulty speaking and swallowing, along with muscle weakness in the legs. Denies pain, sensory changes, or visual disturbances. On examination: Dysarthria, dysphagia, and muscle atrophy with fasciculations in the tongue and legs. Incr...
Amyotrophic Lateral Sclerosis (ALS)**
Adult Female, 3-month history of fatigue, pallor, and shortness of breath. Denies chest pain, fever, or weight loss. On examination: pale conjunctiva and palmar creases, with no jaundice or hepatosplenomegaly. Symptoms are aggravated by exertion. Risk factors include menorrhagia and vegetarian diet. Current med...
Anemia**
Anemia Child Male, 4-week history of pallor, irritability, and poor feeding. Denies vomiting, diarrhea, or fever. On examination: pale skin and tachycardia, with no hepatosplenomegaly or jaundice. Symptoms are relieved by rest. Risk factors include premature birth and low birth weight. Current medications: none...
Anemia**
Child Male, 3 years history of developmental delay, lack of speech, and frequent laughter without apparent stimulus. Denies seizures or regression of milestones. On examination: Microcephaly, ataxic gait, and hyperactive reflexes, with no focal neurological deficits. Symptoms are aggravated by excitement and reliev...
Angelman Syndrome**
Angelman Syndrome Adolescent Female, 15 years history of severe intellectual disability, absence of speech, and frequent episodes of seizures. Denies recent changes in neurological status. On examination: Microcephaly, ataxia, and hyperactive reflexes, with no focal neurological deficits. Symptoms are aggravated by...
Angelman Syndrome**
Adult Male, 5-year history of chronic low back pain and stiffness, worse in the morning. Denies fever, weight loss, or history of trauma. On examination: Limited spinal mobility, positive Schober's test, with no neurological deficits. Symptoms are relieved by exercise and aggravated by rest. Risk factors include ...
Ankylosing Spondylitis**
Ankylosing Spondylitis Adolescent Female, 3-year history of intermittent low back pain and alternating buttock pain. Denies morning stiffness, fever, or weight loss. On examination: Tenderness over the sacroiliac joints, positive FABER test, with no spinal deformities. Symptoms are relieved by NSAIDs and aggravated...
Ankylosing Spondylitis**
Adult Male, 3-week history of persistent fever, cough with purulent sputum, and shortness of breath. Denies hemoptysis, chest pain, or night sweats. On examination: crackles and rhonchi in the right lower lung field, with no wheezing or stridor. Symptoms are aggravated by physical exertion. Risk factors include r...
Antimicrobial-Resistant Infections**
Antimicrobial-Resistant Infections Adolescent Female, 4-day history of high fever, severe abdominal pain, and vomiting. Denies diarrhea, jaundice, or hematemesis. On examination: severe tenderness in the right lower quadrant, guarding, and rebound tenderness, with no hepatosplenomegaly or distension. Symptoms are a...
Antimicrobial-Resistant Infections**
Adult Male, 3-month history of intermittent abdominal pain and pulsating sensation in the abdomen. Denies fever, weight loss, or changes in bowel habits. On examination: pulsatile mass in the epigastric region, with no abdominal tenderness or guarding. Symptoms are aggravated by physical exertion. Risk factors in...
Aortic Aneurysm**
Aortic Aneurysm Adult Female, 2-week history of severe, tearing chest pain radiating to the back. Denies shortness of breath, nausea, or diaphoresis. On examination: asymmetric blood pressure in the arms (right arm 140/80 mmHg, left arm 120/70 mmHg), with no signs of heart failure or peripheral ischemia. Symptoms ...
Aortic Aneurysm**
Child Male, 6-month history of recurrent episodes of wheezing, shortness of breath, and coughing, especially at night and after physical activity. Denies fever, chest pain, or weight loss. On examination: Bilateral expiratory wheezing, mild intercostal retractions, with no cyanosis or clubbing. Symptoms are aggrava...
Asthma**
Asthma Adult Female, 5-year history of episodic shortness of breath, chest tightness, and cough. Denies hemoptysis, weight loss, or fever. On examination: Prolonged expiratory phase, diffuse wheezing, with no cyanosis or clubbing. Symptoms are aggravated by dust, pollen, and respiratory infections; relieved by inha...
Asthma**
Adult Male, 3-month history of palpitations, shortness of breath, and fatigue. Denies chest pain, syncope, or dizziness. On examination: irregularly irregular pulse, tachycardia (heart rate 110 bpm), normal blood pressure, with no signs of heart failure, no murmurs, clear lung fields. Symptoms are aggravated by exe...
Atrial Fibrillation**
Atrial Fibrillation Adult Female, 2-week history of palpitations, lightheadedness, and mild dyspnea. Denies chest pain, syncope, or significant exercise intolerance. On examination: irregularly irregular pulse, tachycardia (heart rate 105 bpm), normal blood pressure, with no signs of heart failure, no murmurs, clear ...
Atrial Fibrillation**
Child Male, 2-year history of frequent fidgeting, difficulty remaining seated, and interrupting others. Denies mood swings, hallucinations, or suicidal ideation. On examination: Observable difficulty staying still, easily distracted, with no signs of physical abnormalities. Symptoms are aggravated by prolonged peri...
Attention Deficit Hyperactivity Disorder (ADHD)**
Attention Deficit Hyperactivity Disorder (ADHD) Adolescent Female, 3-year history of difficulty concentrating, forgetfulness, and impulsive decision-making. Denies substance abuse, anxiety, or depression. On examination: Noticeable restlessness, poor attention span, with no signs of neurological deficits. Symptoms ...
Attention Deficit Hyperactivity Disorder (ADHD)**
Child Male, 2-year history of delayed language development, poor eye contact, and repetitive behaviors such as hand flapping. Denies regression in previously acquired skills, hearing problems, or seizures. On examination: Limited interaction with examiner, lack of joint attention, and stereotyped movements. No neurol...
Autism Spectrum Disorder**
Autism Spectrum Disorder Adolescent Female, 8-year history of social communication difficulties, restricted interests, and sensory sensitivities. Denies intellectual disability, mood disorders, or psychosis. On examination: Difficulty with conversational reciprocity, intense focus on specific topics, and hyperreacti...
Autism Spectrum Disorder**
Adult Male, 5-year history of chronic heartburn and regurgitation. Denies dysphagia, odynophagia, or unintentional weight loss. On examination: mild epigastric tenderness, with no palpable masses or organomegaly. Symptoms are aggravated by lying down after meals and relieved by antacids. Risk factors include chro...
Barrett's Esophagus**
Barrett's Esophagus Adult Female, 3-year history of persistent heartburn and occasional regurgitation. Denies hematemesis, melena, or early satiety. On examination: no abdominal tenderness or distension, with normal bowel sounds. Symptoms are aggravated by large meals and spicy foods, relieved by proton pump inhibi...
Barrett's Esophagus**
Infant, 6-month history of polyuria, polydipsia, and failure to thrive. Denies fever, vomiting, or diarrhea. On examination: Dehydration, muscle weakness, and growth delay, with no signs of edema or hypertension. Symptoms are aggravated by hot weather and relieved by hydration. Risk factors include family history...
Bartter Syndrome**
Bartter Syndrome Adolescent, Female, 10-year history of muscle cramps, fatigue, and frequent urination. Denies abdominal pain, fever, or changes in bowel habits. On examination: Normal blood pressure, mild muscle weakness, and normal growth parameters, with no signs of edema. Symptoms are aggravated by physical ex...
Bartter Syndrome**
Adult Male, 2-year history of a slowly growing, pearly, waxy lesion on the left cheek. Denies pain, itching, or bleeding. On examination: 1 cm pearly, waxy papule with rolled borders and telangiectasias on the left cheek, with no ulceration or regional lymphadenopathy. Symptoms are neither aggravated nor relieved b...
Basal Cell Carcinoma**
Basal Cell Carcinoma Adult Female, 5-month history of a non-healing sore on the nose. Denies significant pain or itching. On examination: 0.5 cm ulcerated lesion with raised, rolled borders on the nose, with no associated telangiectasias or regional lymphadenopathy. Symptoms are not aggravated or relieved by any sp...
Basal Cell Carcinoma**
Case 1: Infant, Male, 3 months history of easy bruising, recurrent epistaxis, and petechiae. Denies joint pain, fever, or weight loss. On examination: Petechiae and purpura on extremities, mild hepatosplenomegaly, with no lymphadenopathy or jaundice. Symptoms are aggravated by minor trauma. Risk factors include ...
Bernard-Soulier Syndrome**
Bernard-Soulier Syndrome Case 2: Child, Female, 5 years history of frequent nosebleeds, gum bleeding, and prolonged bleeding after minor injuries. Denies abdominal pain, nausea, or vomiting. On examination: Multiple bruises on extremities, gingival bleeding, with no signs of infection or organomegaly. Symptoms are...
Bernard-Soulier Syndrome**
Adult Female, 10-year history of alternating periods of elevated mood, increased energy, and decreased need for sleep, lasting 2-3 weeks, followed by weeks of depressed mood, fatigue, and loss of interest in daily activities. Denies suicidal thoughts or hallucinations. On examination: Mild psychomotor agitation durin...
Bipolar Disorder**
Bipolar Disorder Adolescent Male, 2-year history of cyclic mood episodes, including periods of euphoria, increased goal-directed activity, and inflated self-esteem, alternating with episodes of depressed mood, social withdrawal, and irritability. Denies psychotic features. On examination: Increased talkativeness and ...
Bipolar Disorder**
Child Male, 2-year history of recurrent respiratory and ear infections, chronic diarrhea, and poor growth. Denies fever or acute illness. On examination: short stature, microcephaly, narrow facies with prominent nose and ears, and café-au-lait spots on the trunk and limbs. No acute distress or focal neurological defi...
Bloom Syndrome**
Bloom Syndrome Adolescent Female, 15-year history of recurrent pneumonia, chronic diarrhea, and failure to thrive. Denies recent fever or acute symptoms. On examination: severe short stature, microcephaly, narrow facies with prominent nose and ears, and café-au-lait spots on the trunk and limbs. No acute distress or ...
Bloom Syndrome**
Adolescent Female, 2-year history of preoccupation with perceived facial flaws, particularly the shape and size of her nose, which she believes is excessively large and asymmetrical. She spends several hours each day checking her appearance in the mirror and comparing herself to peers and celebrities. Denies history of...
Body Dysmorphic Disorder**
Body Dysmorphic Disorder Adult Male, 5-year history of obsessive thoughts about perceived thinning hair and receding hairline, despite no significant hair loss. He wears hats constantly and avoids social situations where he might need to remove his hat. Denies history of psychosis or mania. On examination: Evidence o...
Body Dysmorphic Disorder**
Adult Female, 5-year history of emotional instability, impulsivity, and a pattern of unstable interpersonal relationships. Denies symptoms of psychosis, mania, or major depression. On examination: Marked reactivity of mood, black-and-white thinking, and signs of self-injury on her arms, with no signs of cognitive imp...
Borderline Personality Disorder**
Borderline Personality Disorder Adolescent Male, 3-year history of fear of abandonment, unstable sense of self, and chronic feelings of emptiness. Denies suicidal ideation but reports episodes of self-harm. On examination: Intense and inappropriate anger, impulsive behavior, and transient stress-related paranoid idea...
Borderline Personality Disorder**
Adult Male, 3-month history of progressive headaches, nausea, and vomiting. Denies fever, weight loss, or changes in vision. On examination: papilledema, mild left-sided weakness, with no sensory deficits or cranial nerve palsies. Symptoms are aggravated by bending forward or coughing. Risk factors include histor...
Brain Tumor**
Brain Tumor Child Female, 2-week history of morning headaches, seizures, and behavioral changes. Denies fever, nausea, or vomiting. On examination: macrocephaly, ataxia, with no focal neurological deficits. Symptoms are relieved by rest and pain medication. Risk factors include family history of neurofibromatosi...
Brain Tumor**
Adult Female, 5-year history of chronic productive cough with purulent sputum, recurrent respiratory infections, and exertional dyspnea. Denies hemoptysis or chest pain. On examination: Bilateral coarse crackles, clubbing of the fingernails, with no signs of cyanosis or peripheral edema. Symptoms are aggravated by ...
Bronchiectasis**
Bronchiectasis --- Adolescent Male, 3-year history of persistent wet cough, frequent respiratory infections, and occasional wheezing. Denies fever or weight loss. On examination: Diffuse inspiratory crackles, mild clubbing of the fingernails, with no signs of respiratory distress or cyanosis. Symptoms are relieved ...
Bronchiectasis**
Adult Female, 5-day history of productive cough with yellowish sputum, wheezing, and mild chest discomfort. Denies hemoptysis, fever, or weight loss. On examination: Wheezing and rhonchi on auscultation, with no signs of respiratory distress or cyanosis. Symptoms are aggravated by cold air and relieved by rest. R...
Bronchitis**
Bronchitis Child Male, 3-day history of persistent cough, low-grade fever, and mild shortness of breath. Denies wheezing, hemoptysis, or chest pain. On examination: Mild respiratory distress, coarse breath sounds, and rhonchi on auscultation, with no signs of cyanosis. Symptoms are aggravated by physical activity a...
Bronchitis**
Adult Male, 3-week history of pain and swelling over the left elbow, particularly noticeable with elbow flexion. Denies fever, chills, or other joint pain. On examination: Tenderness and swelling over the olecranon bursa, with no warmth or erythema. Symptoms are aggravated by leaning on the elbow or direct pressure...
Olecranon Bursitis**
Olecranon Bursitis Adult Female, 2-month history of pain and stiffness in the right hip, worsening over the past week. Denies fever, weight loss, or night sweats. On examination: Tenderness over the greater trochanter, with no warmth, erythema, or limited range of motion in the hip joint. Symptoms are aggravated by...
Trochanteric Bursitis**
Adult Male, 3-month history of a painless ulcer on the left forearm. Denies fever, night sweats, or weight loss. On examination: Single, well-demarcated ulcer with undermined edges and a necrotic base, approximately 5 cm in diameter, with surrounding induration and erythema. No regional lymphadenopathy. Symptoms ar...
Buruli Ulcer**
Buruli Ulcer Child Female, 2-month history of a painless, swollen right knee. Denies trauma, fever, or other systemic symptoms. On examination: Swollen right knee with a small, central ulceration, approximately 2 cm in diameter, with undermined edges. Limited range of motion due to swelling. No warmth or erythema. ...
Buruli Ulcer**
Infant, Male, 2 months history of feeding difficulties, frequent respiratory infections, and delayed developmental milestones. Denies fever or weight gain. On examination: Coloboma of the iris, microphthalmia, choanal atresia, and hearing loss, with no signs of cardiac abnormalities. Symptoms are aggravated by feed...
CHARGE Syndrome**
CHARGE Syndrome Child, Female, 4 years history of recurrent ear infections, hearing loss, and delayed speech development. Denies vision problems or cardiac symptoms. On examination: Coloboma of the retina, microtia, and facial palsy, with no signs of respiratory distress. Symptoms are relieved by antibiotic treatm...
CHARGE Syndrome**
Adult Female, 5 days history of fever, dry cough, and shortness of breath. Denies loss of taste or smell, gastrointestinal symptoms. On examination: tachypnea, bilateral crackles on auscultation, with no wheezing, no signs of cyanosis. Symptoms are aggravated by exertion. Risk factors include hypertension, obesit...
COVID-19**
COVID-19 Child Male, 3 days history of fever, cough, and fatigue. Denies shortness of breath, gastrointestinal symptoms. On examination: mild tachypnea, clear lungs on auscultation, with no signs of respiratory distress. Symptoms are relieved by rest. Risk factors include asthma. Current medications: Albuterol ...
COVID-19**
Adult Male, 3-week history of fever and chills. Denies cough, shortness of breath, or gastrointestinal symptoms. On examination: Fever (38.5°C), tachycardia, with no localizing signs of infection. Symptoms are not relieved by over-the-counter antipyretics. Risk factors include recent hospitalization for a surgica...
Candida auris Infection**
Candida auris Infection Adult Female, 2-month history of persistent fever and recent onset of altered mental status. Denies headache, photophobia, or neck stiffness. On examination: Fever (39°C), confusion, nuchal rigidity, with no focal neurological deficits. Symptoms are aggravated by lack of antifungal treatment...
Candida auris Infection**
Adult Male, 6-month history of progressive shortness of breath, fatigue, and peripheral edema. Denies chest pain, palpitations, or syncope. On examination: Jugular venous distention, bilateral basilar crackles, and S3 gallop, with no murmurs or friction rub. Symptoms are aggravated by exertion and relieved by rest....
Dilated Cardiomyopathy**
Dilated Cardiomyopathy Adolescent Female, 3-month history of intermittent chest pain, palpitations, and occasional syncope. Denies shortness of breath, fatigue, or peripheral edema. On examination: Systolic murmur best heard at the left sternal border, no jugular venous distention or crackles. Symptoms are aggrava...
Hypertrophic Cardiomyopathy**
Adult Female, 6-month history of numbness and tingling in the thumb, index, and middle fingers, worsening at night. Denies pain in the wrist or hand, weakness in the fingers. On examination: positive Tinel's sign and Phalen's sign, with no muscle atrophy or weakness. Symptoms are aggravated by repetitive hand movem...
Carpal Tunnel Syndrome**
Carpal Tunnel Syndrome Adult Male, 3-year history of pain and numbness in the thumb, index, and middle fingers, with occasional weakness in the thumb. Denies trauma to the wrist or hand. On examination: positive Tinel's sign and Phalen's sign, mild thenar muscle atrophy. Symptoms are aggravated by gripping objects...
Carpal Tunnel Syndrome**
Adult Male, 2-year history of gradual vision loss, glare sensitivity, and difficulty reading. Denies eye pain, redness, or sudden vision changes. On examination: Bilateral lens opacities, with normal intraocular pressure and intact extraocular movements. Symptoms are aggravated by bright light and night driving. ...
Cataracts**
Cataracts Adult Female, 5-year history of progressive blurry vision and difficulty with color perception. Denies eye discharge, itching, or diplopia. On examination: Bilateral nuclear sclerosis of the lenses, with clear corneas and normal funduscopic exam. Symptoms are relieved by using brighter lighting and magni...
Cataracts**
Child, Female, 6-month history of chronic diarrhea, abdominal distension, and failure to thrive. Denies fever, vomiting, or blood in stool. On examination: pale conjunctivae, abdominal distension, and generalized muscle wasting, with no abdominal tenderness. Symptoms are aggravated by ingestion of gluten-containing...
Celiac Disease**
Celiac Disease Adult, Female, 2-year history of intermittent diarrhea, fatigue, and unintentional weight loss. Denies abdominal pain, vomiting, or blood in stool. On examination: mild pallor, mild abdominal distension, with no abdominal tenderness. Symptoms are relieved by adherence to a gluten-free diet. Risk f...
Celiac Disease**
Adult Male, 3-day history of redness, swelling, and pain in the right lower leg. Denies fever, chills, or nausea. On examination: erythema, warmth, and tenderness over the right shin, with no fluctuance or crepitus. Symptoms are aggravated by dependency and walking, partially relieved by elevation and rest. Risk ...
Cellulitis**
Cellulitis Adolescent Female, 2-day history of pain, redness, and warmth on the left forearm. Denies fever or systemic symptoms. On examination: erythema, warmth, and swelling over the left forearm, with no lymphangitis or lymphadenopathy. Symptoms are aggravated by movement and touch, partially relieved by rest. ...
Cellulitis**
Child Male, 3-year history of delayed motor milestones and muscle stiffness. Denies sensory deficits or cognitive impairment. On examination: Spasticity in lower limbs, exaggerated deep tendon reflexes, and scissoring gait, with no muscle atrophy or sensory loss. Symptoms are aggravated by physical activity and rel...
Cerebral Palsy**
Cerebral Palsy Adolescent Female, 15-year history of difficulty with fine motor skills and coordination. Denies seizures or vision problems. On examination: Dyskinetic movements, impaired fine motor skills, and mild speech difficulties, with no sensory deficits or cognitive impairment. Symptoms are aggravated by s...
Cerebral Palsy**
Adult Female, 6 months history of postcoital bleeding, persistent vaginal discharge, and pelvic pain. Denies changes in bowel or bladder habits. On examination: visible cervical lesion on speculum exam, with no palpable inguinal lymph nodes. Symptoms are aggravated by sexual intercourse. Risk factors include early onse...
Cervical Cancer**
Cervical Cancer Adult Female, 1 year history of intermenstrual bleeding, postmenopausal spotting, and lower back pain. Denies weight loss or abdominal distension. On examination: cervical mass visible on speculum exam, with palpable left inguinal lymph node. Symptoms are relieved by rest and aggravated by prolonged sta...
Cervical Cancer**
Adult Female, 6-month history of fever, fatigue, and occasional shortness of breath. Denies chest pain, cough, or hemoptysis. On examination: mild hepatomegaly, splenomegaly, and a soft systolic murmur, with no signs of heart failure or pulmonary congestion. Symptoms are aggravated by exertion. Risk factors inclu...
Chagas Disease**
Chagas Disease Adolescent Male, 2-year history of intermittent fever, malaise, and progressive dyspnea. Denies syncope or angina. On examination: cardiomegaly, bibasilar rales, and a grade II/VI holosystolic murmur, with no peripheral edema. Symptoms are aggravated by physical activity. Risk factors include resid...
Chagas Disease**
Child Male, 5-day history of fever, malaise, and a pruritic rash that initially appeared on his trunk and has spread to his face and extremities. Denies cough, shortness of breath, or abdominal pain. On examination: Widespread vesicular rash in various stages of development, with some lesions crusted over. Mild dehyd...
Chickenpox**
Chickenpox Adult Female, 7-day history of fever, headache, and a diffuse, itchy rash that started on her back and has spread to her arms and legs. Denies nausea, vomiting, or respiratory symptoms. On examination: Characteristic varicella rash with macules, papules, vesicles, and crusts present. No signs of pneumonia ...
Chickenpox**
Adult Male, 3-day history of high fever, severe joint pain, and rash. Denies nausea, vomiting, or respiratory symptoms. On examination: bilateral swelling and tenderness of wrists, ankles, and knees, with no neurological deficits. Symptoms are aggravated by movement and relieved by rest. Risk factors include rece...
Chikungunya**
Chikungunya Adolescent Female, 5-day history of fever, muscle pain, and joint stiffness. Denies headache, abdominal pain, or cough. On examination: erythematous maculopapular rash on the trunk and limbs, joint tenderness in the fingers and toes, with no lymphadenopathy. Symptoms are aggravated by physical activity ...
Chikungunya**
Adult Male, 3-day history of profuse watery diarrhea, vomiting, and severe dehydration. Denies fever, abdominal pain, or blood in stool. On examination: marked dehydration, weak pulse, dry mucous membranes, and decreased skin turgor, with no abdominal tenderness or distension. Symptoms are aggravated by oral intake...
Cholera**
Cholera Child Female, 2-day history of frequent, pale, watery stools, vomiting, and signs of moderate dehydration. Denies fever, abdominal pain, or blood in stool. On examination: dry mucous membranes, decreased skin turgor, weak pulse, with no abdominal tenderness or distension. Symptoms are aggravated by oral int...
Cholera**
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