Datasets:

Kiria-Nozan
/

Starling-bioavailability-transfer

completion stringclasses 2 values	metadata dict	prompt stringlengths 1.15k 2.2k
B	{ "abs_activity_delta": 58.47, "assay_type": "oral_bioavailability_literature", "condition_index": 12, "condition_key": "ducks\|po\|not_specified\|not_specified", "condition_key_hash": "17c14d81e5ae40f3", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "oral_bioa...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 58.47, "assay_type": "oral_bioavailability_literature", "condition_index": 12, "condition_key": "ducks\|po\|not_specified\|not_specified", "condition_key_hash": "17c14d81e5ae40f3", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "oral_bioa...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 78.2, "assay_type": "oral_bioavailability_literature", "condition_index": 12, "condition_key": "ducks\|po\|not_specified\|not_specified", "condition_key_hash": "17c14d81e5ae40f3", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "oral_bioav...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 78.2, "assay_type": "oral_bioavailability_literature", "condition_index": 12, "condition_key": "ducks\|po\|not_specified\|not_specified", "condition_key_hash": "17c14d81e5ae40f3", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "oral_bioav...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 33.22, "assay_type": "oral_bioavailability_literature", "condition_index": 12, "condition_key": "ducks\|po\|not_specified\|not_specified", "condition_key_hash": "17c14d81e5ae40f3", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "oral_bioa...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 33.22, "assay_type": "oral_bioavailability_literature", "condition_index": 12, "condition_key": "ducks\|po\|not_specified\|not_specified", "condition_key_hash": "17c14d81e5ae40f3", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "oral_bioa...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 52.95, "assay_type": "oral_bioavailability_literature", "condition_index": 12, "condition_key": "ducks\|po\|not_specified\|not_specified", "condition_key_hash": "17c14d81e5ae40f3", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "oral_bioa...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 52.95, "assay_type": "oral_bioavailability_literature", "condition_index": 12, "condition_key": "ducks\|po\|not_specified\|not_specified", "condition_key_hash": "17c14d81e5ae40f3", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "oral_bioa...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 6, "assay_type": "oral_bioavailability_literature", "condition_index": 78, "condition_key": "turkey\|oral administration\|not_specified\|not_specified", "condition_key_hash": "b799811a6a06623d", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_i...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 6, "assay_type": "oral_bioavailability_literature", "condition_index": 78, "condition_key": "turkey\|oral administration\|not_specified\|not_specified", "condition_key_hash": "b799811a6a06623d", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_i...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 42.09, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": ...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 42.09, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": ...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 47.841, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id":...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 47.841, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id":...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 51.3, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 51.3, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 5.751, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": ...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 5.751, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": ...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 9.21, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 9.21, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 3.459, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": ...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 3.459, "assay_type": "oral_bioavailability_literature", "condition_index": 80, "condition_key": "rats\|oral administration\|not_specified\|vs i.v.", "condition_key_hash": "d17dec855a0d7b50", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": ...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 45, "assay_type": "oral_bioavailability_literature", "condition_index": 81, "condition_key": "cynomolgus monkeys\|po\|formulation 1% dmso 9.9% cremophor el in 50 mm pbs ph 7.4\|vs iv", "condition_key_hash": "b4b6d11f39629f9c", "different_delta_threshold": 30, "direction": "directed_re...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 45, "assay_type": "oral_bioavailability_literature", "condition_index": 81, "condition_key": "cynomolgus monkeys\|po\|formulation 1% dmso 9.9% cremophor el in 50 mm pbs ph 7.4\|vs iv", "condition_key_hash": "b4b6d11f39629f9c", "different_delta_threshold": 30, "direction": "directed_re...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 5, "assay_type": "oral_bioavailability_literature", "condition_index": 81, "condition_key": "cynomolgus monkeys\|po\|formulation 1% dmso 9.9% cremophor el in 50 mm pbs ph 7.4\|vs iv", "condition_key_hash": "b4b6d11f39629f9c", "different_delta_threshold": 30, "direction": "directed_ref...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 5, "assay_type": "oral_bioavailability_literature", "condition_index": 81, "condition_key": "cynomolgus monkeys\|po\|formulation 1% dmso 9.9% cremophor el in 50 mm pbs ph 7.4\|vs iv", "condition_key_hash": "b4b6d11f39629f9c", "different_delta_threshold": 30, "direction": "directed_ref...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 7.7, "assay_type": "oral_bioavailability_literature", "condition_index": 88, "condition_key": "cd-1 mice\|oral gavage\|prepared as acetic salts\|vs iv", "condition_key_hash": "5b2fc93053c8eb22", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_i...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 7.7, "assay_type": "oral_bioavailability_literature", "condition_index": 88, "condition_key": "cd-1 mice\|oral gavage\|prepared as acetic salts\|vs iv", "condition_key_hash": "5b2fc93053c8eb22", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_i...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 6.8, "assay_type": "oral_bioavailability_literature", "condition_index": 88, "condition_key": "cd-1 mice\|oral gavage\|prepared as acetic salts\|vs iv", "condition_key_hash": "5b2fc93053c8eb22", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_i...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 6.8, "assay_type": "oral_bioavailability_literature", "condition_index": 88, "condition_key": "cd-1 mice\|oral gavage\|prepared as acetic salts\|vs iv", "condition_key_hash": "5b2fc93053c8eb22", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_i...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 0.9, "assay_type": "oral_bioavailability_literature", "condition_index": 88, "condition_key": "cd-1 mice\|oral gavage\|prepared as acetic salts\|vs iv", "condition_key_hash": "5b2fc93053c8eb22", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_i...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 0.9, "assay_type": "oral_bioavailability_literature", "condition_index": 88, "condition_key": "cd-1 mice\|oral gavage\|prepared as acetic salts\|vs iv", "condition_key_hash": "5b2fc93053c8eb22", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_i...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 3, "assay_type": "oral_bioavailability_literature", "condition_index": 93, "condition_key": "adult male sprague dawley rats\|oral dosing\|not_specified\|vs iv", "condition_key_hash": "649bb8acb9cafa2e", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "en...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 3, "assay_type": "oral_bioavailability_literature", "condition_index": 93, "condition_key": "adult male sprague dawley rats\|oral dosing\|not_specified\|vs iv", "condition_key_hash": "649bb8acb9cafa2e", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "en...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 31.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 31.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 57.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 57.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 30.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 30.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 55.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 55.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 37.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 37.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 7.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "o...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 7.5, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "o...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 3.3, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "o...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 3.3, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "o...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 50.7, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 50.7, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 36.7, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 36.7, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 38.3, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 38.3, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 36.3, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 36.3, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 37.7, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 37.7, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 54, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 54, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 40, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 40, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 35, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 35, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 8, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "ora...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
A	{ "abs_activity_delta": 8, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "ora...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 33, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 33, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 41, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...
B	{ "abs_activity_delta": 41, "assay_type": "oral_bioavailability_literature", "condition_index": 148, "condition_key": "men\|not_specified\|not_specified\|not_specified", "condition_key_hash": "1e7e07e65515c598", "different_delta_threshold": 30, "direction": "directed_reference_to_query", "endpoint_id": "or...	You are given two molecules and an oral bioavailability endpoint. Decide whether the endpoint behavior should transfer between the molecules. ## Endpoint - Measurement type: oral_bioavailability_percent - Endpoint description: absolute oral bioavailability or explicitly numeric oral/systemic availability - Similar lab...

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Starling Oral Bioavailability Transfer

This dataset is a molecule-disjoint pairwise benchmark derived from starling-labs/Oral_Bioavailability. Each row is a prompt/completion example with metadata for audit and reproducibility.

Task

Decide whether oral bioavailability transfers between Molecule A and Molecule B.

Completion labels:

A: similar
B: different

Label rule: similar if absolute oral bioavailability difference is <= 10 percentage points; different if absolute difference is >= 30 percentage points; ambiguous pairs are excluded.

Splits

split	rows	file	label counts
train	1312272	`train.jsonl.gz`	{'different': 930112, 'similar': 382160}
validation	177854	`validation.jsonl.gz`	{'different': 126588, 'similar': 51266}
test	400360	`test.jsonl.gz`	{'different': 287850, 'similar': 112510}

Schema

Each line in data/*.jsonl.gz is a JSON object:

{
  "prompt": "string",
  "completion": "A or B",
  "metadata": {
    "label_text": "string",
    "reference_activity_value": 0.0,
    "hidden_query_activity_value": 0.0,
    "reference_aggregate_id": "string",
    "query_aggregate_id": "string",
    "condition_key": "string",
    "weighted_tanimoto": 0.0
  }
}

The prompt hides Molecule B's oral bioavailability value. The hidden value and the resolved label are kept in metadata for supervised training and auditing.

Construction Notes

Source dataset: starling-labs/Oral_Bioavailability, split train.
Clean rows keep absolute, unspecified, and systemic_availability report types when the oral bioavailability value can be parsed as an explicit numeric percent.
Split mode is molecule-disjoint by canonical SMILES. The same molecule does not appear across train, validation, and test.
Experimental context fields are preserved in the prompt and metadata.
Original local source run: absolute_unspecified_systemic_directed_molecule_disjoint_pairratio_7_1_2_v1.

Citation / Attribution

Please cite or attribute the upstream starling-labs/Oral_Bioavailability dataset when using this benchmark.

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