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In spite of multiple treatment regimens consisting of surgical resection , radiation therapy , and multi-agent chemotherapy , the prognosis is very poor .
{ "id": "C0015252", "pos": [ 54, 72 ], "name": "surgical resection" }
{ "id": "C0033325", "pos": [ 130, 139 ], "name": "prognosis" }
0NA
HIIC can kill isolated intraperitoneal cancer cells , reduce peritoneal recurrence rate after operations , raise significantly survival rate of patient , and improve the prognosis of AGC .
{ "id": "C0031153", "pos": [ 61, 71 ], "name": "peritoneal" }
{ "id": "C0033325", "pos": [ 170, 179 ], "name": "prognosis" }
0NA
The surface features of the femoral footprints of the anterolateral and posteromedial bundles of the posterior cruciate ligament were studied by means of macroscopic observation and three-dimensional laser photography .
{ "id": "C0080039", "pos": [ 101, 128 ], "name": "posterior cruciate ligament" }
{ "id": "C0015811", "pos": [ 28, 35 ], "name": "femoral" }
0NA
To investigate the correlations between MFALC structures and lung injuries in B6 mice , histopathological examination of mediastinal fat tissues and lungs was examined at 7 and 21   days ( d ) following a single 50   μL intranasal ( i.n . ) instillation of either BLM sulfate ( 5   mg/kg ) ( BLM group ) or phosphate-buffered saline ( control group ) .
{ "id": "C0024109", "pos": [ 149, 154 ], "name": "lungs" }
{ "id": "C0273115", "pos": [ 61, 74 ], "name": "lung injuries" }
11finding_site_of
Proximal situation of the toe gives the possibility of having plenty of tendons to balance the transfer .
{ "id": "C0039508", "pos": [ 72, 79 ], "name": "tendons" }
{ "id": "C0014653", "pos": [ 83, 90 ], "name": "balance" }
0NA
Adenoidal development seems to differ from that of other lymphatic tissues , showing a peculiar pattern that can be revealed when hypertrophy due to infections and allergies is eliminated .
{ "id": "C0020564", "pos": [ 130, 141 ], "name": "hypertrophy" }
{ "id": "C0024296", "pos": [ 57, 74 ], "name": "lymphatic tissues" }
0NA
For these applications , ohmic losses resulting from free-electron scattering in the metal is one major limitation for the performance of plasmonic structures .
{ "id": "C0025552", "pos": [ 85, 90 ], "name": "metal" }
{ "id": "C0185125", "pos": [ 10, 22 ], "name": "applications" }
0NA
Drug induced effects on the various endocrine and metabolic processes constitute a very common differential diagnostic possibility in investigating endocrine disorders .
{ "id": "C0013227", "pos": [ 0, 4 ], "name": "Drug" }
{ "id": "C0014130", "pos": [ 148, 167 ], "name": "endocrine disorders" }
0NA
Patients with oral and oropharyngeal cancer responding to split-dose TPF before surgery and postoperative RCT show good oncological results .
{ "id": "C0226896", "pos": [ 14, 18 ], "name": "oral" }
{ "id": "C0153382", "pos": [ 23, 43 ], "name": "oropharyngeal cancer" }
0NA
In the first case , an aneurysm of the PDA was demonstrated with stenosis of the celiac trunk ; in the second case occlusion of the hepatic artery was shown .
{ "id": "C0002940", "pos": [ 23, 31 ], "name": "aneurysm" }
{ "id": "C0019145", "pos": [ 132, 146 ], "name": "hepatic artery" }
0NA
The compounds of interest were separated and eluted in fewer than 20 minutes , using a mobile phase consisting of 37.5 acetonitril:62.5 water , containing 0.4 % ( vol/vol ) tetramethylethylenediamine and adjusted to pH 6.5 with concentrated acetic acid .
{ "id": "C0000983", "pos": [ 241, 252 ], "name": "acetic acid" }
{ "id": "C0043047", "pos": [ 136, 141 ], "name": "water" }
0NA
Sixty-four patients with HRS type-1 received vasoconstrictors ( 40 terlipressin and 24 midodrine/octreotide ) .
{ "id": "C0042397", "pos": [ 45, 61 ], "name": "vasoconstrictors" }
{ "id": "C0145185", "pos": [ 67, 79 ], "name": "terlipressin" }
0NA
Other fractures that increase with age include radius and cubitus , shine and fibula , ankle , humerus and femur .
{ "id": "C0020164", "pos": [ 95, 102 ], "name": "humerus" }
{ "id": "C0013769", "pos": [ 58, 65 ], "name": "cubitus" }
0NA
Syphilis infection was associated with older age , less education , inconsistent condom use with a man , STD-related symptoms , and HIV infection .
{ "id": "C0039128", "pos": [ 0, 8 ], "name": "Syphilis" }
{ "id": "C0009450", "pos": [ 9, 18 ], "name": "infection" }
0NA
None of the dogs in any groups showed any adverse effects or change in liver or kidney function markers or body weight .
{ "id": "C0023884", "pos": [ 71, 76 ], "name": "liver" }
{ "id": "C0005910", "pos": [ 107, 118 ], "name": "body weight" }
0NA
Both microsurgical subinguinal and high inguinal approaches yielded comparable success rates , but the operative time and pain control were superior with the high inguinal approach .
{ "id": "C0018246", "pos": [ 167, 175 ], "name": "inguinal" }
{ "id": "C0002766", "pos": [ 124, 136 ], "name": "pain control" }
0NA
A simultaneous stimulation of these two enzymes was reported at high dilutions of antisera directed against antigens of the MHC .
{ "id": "C1292856", "pos": [ 15, 26 ], "name": "stimulation" }
{ "id": "C0020960", "pos": [ 82, 90 ], "name": "antisera" }
0NA
The severity of the disability and complications was evaluated at 6 years of age in 202 cases of cerebral palsy ( CP ) in Shiga Prefecture ( 69 with spastic diplegia , 62 with tetraplegia , 33 with hemiplegia , 23 with the dyskinetic type and 15 with the ataxic type ) born between April 1977 and March 1987 .
{ "id": "C0231170", "pos": [ 20, 30 ], "name": "disability" }
{ "id": "C0007789", "pos": [ 97, 111 ], "name": "cerebral palsy" }
0NA
In addition , inhibition of lipogenic enzymes and reduced expression of CD44 attenuated the activation of MET , Akt , FAK , and paxillin , which are known to regulate adhesion , migration , and invasion .
{ "id": "C0001511", "pos": [ 167, 175 ], "name": "adhesion" }
{ "id": "C0025646", "pos": [ 106, 109 ], "name": "MET" }
0NA
It was possible to reroute the testes underneath inferior epigastric artery ( IEA ) without its mobilization and thus locate testicular pedicle through a fascial hole above pubic tubercle , well medial to IEA .
{ "id": "C0034014", "pos": [ 173, 178 ], "name": "pubic" }
{ "id": "C0185112", "pos": [ 96, 108 ], "name": "mobilization" }
0NA
Administration of sugar test by these persons revealed high levels of insulin incretion and low insulin reactivity of tissues or insulin resistance .
{ "id": "C0040300", "pos": [ 118, 125 ], "name": "tissues" }
{ "id": "C0337438", "pos": [ 18, 28 ], "name": "sugar test" }
0NA
All 6 prognostication systems were useful in the prognostication of pancreatic neuroendocrine neoplasm .
{ "id": "C0030274", "pos": [ 68, 78 ], "name": "pancreatic" }
{ "id": "C0206754", "pos": [ 79, 102 ], "name": "neuroendocrine neoplasm" }
0NA
The aim of this study was to determine the efficacy of this technique for prevention of post- ERCP pancreatitis .
{ "id": "C0199176", "pos": [ 74, 84 ], "name": "prevention" }
{ "id": "C0030305", "pos": [ 99, 111 ], "name": "pancreatitis" }
0NA
serum FT(3 ) , FT(4 ) and thyrotropin levels as well as acute inflammation indexes were evaluated .
{ "id": "C0333361", "pos": [ 56, 74 ], "name": "acute inflammation" }
{ "id": "C0040160", "pos": [ 26, 37 ], "name": "thyrotropin" }
0NA
Urine samples were analyzed to determine detection sensitivity for four antipsychotic medications and their metabolites ( risperidone , quetiapine , olanzapine , and/or haloperidol ) using Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry .
{ "id": "C0171023", "pos": [ 149, 159 ], "name": "olanzapine" }
{ "id": "C0123091", "pos": [ 136, 146 ], "name": "quetiapine" }
0NA
These results suggest that Livin knockdown can inhibit cell growth and increase sensitivity to apoptotic stimuli , and might serve as a potent target in bladder cancer gene therapy .
{ "id": "C0005684", "pos": [ 153, 167 ], "name": "bladder cancer" }
{ "id": "C0020517", "pos": [ 80, 91 ], "name": "sensitivity" }
0NA
Blood flow in the cannulated arm increased significantly during the first ANP infusion ; by 52 + /- 15 % before placebo ( P less than 0.05 ) , and by 41 + /- 8 % before enalaprilat ( P less than 0.005 ) .
{ "id": "C0027481", "pos": [ 74, 77 ], "name": "ANP" }
{ "id": "C0574032", "pos": [ 78, 86 ], "name": "infusion" }
0NA
Tissue water increased in skeletal muscle after IPR injection , reflecting a change of intracellular water as inulin space was maintained .
{ "id": "C0021485", "pos": [ 52, 61 ], "name": "injection" }
{ "id": "C0043047", "pos": [ 101, 106 ], "name": "water" }
0NA
Patients were excluded if they had a previous transurethral resection of the prostate ( TURP ) or prostate radiation therapy .
{ "id": "C0033572", "pos": [ 77, 85 ], "name": "prostate" }
{ "id": "C0040771", "pos": [ 88, 92 ], "name": "TURP" }
9direct_procedure_site_of
All these drugs induce increased undirectional Ca2 + efflux .
{ "id": "C0013227", "pos": [ 10, 15 ], "name": "drugs" }
{ "id": "C0666743", "pos": [ 47, 50 ], "name": "Ca2" }
0NA
infusion model and observation of changes in the microvasculature of the cremaster muscle of rats .
{ "id": "C0574032", "pos": [ 0, 8 ], "name": "infusion" }
{ "id": "C0224377", "pos": [ 73, 89 ], "name": "cremaster muscle" }
0NA
The resected specimen contained a cystic lesion , 10 x 10 mm in diameter , in the head of the pancreas .
{ "id": "C0030274", "pos": [ 94, 102 ], "name": "pancreas" }
{ "id": "C0015252", "pos": [ 4, 12 ], "name": "resected" }
0NA
Two authors will independently screen and extract data from articles using a predetermined screening and extraction forms ( which will include risk of bias assessments ) .
{ "id": "C1261322", "pos": [ 156, 167 ], "name": "assessments" }
{ "id": "C0199230", "pos": [ 91, 100 ], "name": "screening" }
17method_of
Laser-induced dissociation ( unimolecular decay ) of higher mass ( > 5 kDa ) precursor ions in the first TOF analyzer is followed by reacceleration and subsequent high-resolution mass analysis of the resulting sequence-specific fragments in a reflectron TOF analyzer .
{ "id": "C0577559", "pos": [ 60, 64 ], "name": "mass" }
{ "id": "C0039685", "pos": [ 105, 108 ], "name": "TOF" }
0NA
Computed tomography imaging of the chest , the abdomen , and the pelvis revealed no evidence of metastasis .
{ "id": "C0729619", "pos": [ 0, 27 ], "name": "Computed tomography imaging" }
{ "id": "C0817096", "pos": [ 35, 40 ], "name": "chest" }
0NA
Neither intervention had effects on attention .
{ "id": "C0184661", "pos": [ 8, 20 ], "name": "intervention" }
{ "id": "C0004268", "pos": [ 36, 45 ], "name": "attention" }
0NA
Based on these characteristics , on re-review , the masked neuroradiologist was able to differentiate a CVM versus other tumors for all 14 imaging cases .
{ "id": "C0027651", "pos": [ 121, 127 ], "name": "tumors" }
{ "id": "C0011923", "pos": [ 139, 146 ], "name": "imaging" }
0NA
All participants received ondansetron 0.15   mg/kg and dexamethasone 0.25   mg/kg , up to 10   mg .
{ "id": "C0011777", "pos": [ 55, 68 ], "name": "dexamethasone" }
{ "id": "C0061851", "pos": [ 26, 37 ], "name": "ondansetron" }
0NA
The energy needed to displace water from the glucose binding pocket depended on the amino acid at the entrance , in agreement with the different amounts of enthalpy-entropy compensation found for introducing glucose into the pocket in the different mutants .
{ "id": "C0017725", "pos": [ 208, 215 ], "name": "glucose" }
{ "id": "C0002520", "pos": [ 84, 94 ], "name": "amino acid" }
0NA
Among the 42 , 443 examined using a cotton tipped applicator , there were 15 ( 0.035 % ) with mild dysplasia , 8 ( 0.019 % ) with severe dysplasia , 6 ( 0.014 % ) with carcinoma in situ and 8 ( 0.019 % ) with invasive carcinoma .
{ "id": "C0334044", "pos": [ 137, 146 ], "name": "dysplasia" }
{ "id": "C0007097", "pos": [ 168, 177 ], "name": "carcinoma" }
0NA
Aneurysm of the interatrial septum is a potential cause of systemic embolism , but it is rarely responsible for a cerebral embolism in childhood .
{ "id": "C0002940", "pos": [ 0, 8 ], "name": "Aneurysm" }
{ "id": "C0225836", "pos": [ 16, 34 ], "name": "interatrial septum" }
0NA
The preconditioning routine did not decrease nerve or tendon location variability in either the neutral or the flexed wrist positions .
{ "id": "C0027740", "pos": [ 45, 50 ], "name": "nerve" }
{ "id": "C0039508", "pos": [ 54, 60 ], "name": "tendon" }
0NA
Esophagogastroduodenoscopy showed an ulceroinfiltrating lesion at the stomach ( Borrmann class III ) , and biopsy revealed a signet ring cell carcinoma .
{ "id": "C0005558", "pos": [ 107, 113 ], "name": "biopsy" }
{ "id": "C0079304", "pos": [ 0, 26 ], "name": "Esophagogastroduodenoscopy" }
0NA
The postoperative IADSA showed total occlusion of the aneurysm with patency of the artery of Percheron .
{ "id": "C0002940", "pos": [ 54, 62 ], "name": "aneurysm" }
{ "id": "C0003842", "pos": [ 83, 89 ], "name": "artery" }
0NA
Eighteen different gene cassette arrays were detected , most of them coding for resistances to aminoglycosides , trimethoprim , chloramphenicol , and quaternary ammonia compounds .
{ "id": "C0041041", "pos": [ 113, 125 ], "name": "trimethoprim" }
{ "id": "C0002556", "pos": [ 95, 110 ], "name": "aminoglycosides" }
0NA
Infection with Helicobacter pylori has been linked to chronic gastritis with atrophy or hyperrugosity .
{ "id": "C0009450", "pos": [ 0, 9 ], "name": "Infection" }
{ "id": "C0085695", "pos": [ 54, 71 ], "name": "chronic gastritis" }
0NA
Family-oriented stroke rehabilitation may reduce depression in stroke survivors and their family caregivers .
{ "id": "C0034991", "pos": [ 23, 37 ], "name": "rehabilitation" }
{ "id": "C0038454", "pos": [ 63, 69 ], "name": "stroke" }
0NA
In the first round , this " randomisation " assigned 19/24 late stage cancers to the mammography group and only five to the control group , supporting the suspicion of severe errors in the randomisation process .
{ "id": "C0205082", "pos": [ 168, 174 ], "name": "severe" }
{ "id": "C0024671", "pos": [ 85, 96 ], "name": "mammography" }
0NA
In these studies , conventional prognostic factors for SC , including ascites , an advanced International Federation of Gynecology and Obstetrics ( FIGO ) stage and/or peritoneal carcinomatosis , did not apply to TC , but the post-operative residual tumor load was significant in determining the prognosis .
{ "id": "C0031153", "pos": [ 168, 178 ], "name": "peritoneal" }
{ "id": "C0033325", "pos": [ 296, 305 ], "name": "prognosis" }
0NA
It has been shown that even though intramuscular and intradermal immunization with these vaccines generates strong systemic responses , mucosal responses are not induced .
{ "id": "C0020971", "pos": [ 65, 77 ], "name": "immunization" }
{ "id": "C0042210", "pos": [ 89, 97 ], "name": "vaccines" }
0NA
Right eye and left eye had a similar trend of diurnal cycle .
{ "id": "C0229090", "pos": [ 14, 22 ], "name": "left eye" }
{ "id": "C0229089", "pos": [ 0, 9 ], "name": "Right eye" }
0NA
HIV men with peak GH < 7.5 μg/l demonstrated higher BMI , WC , SBP , triglycerides , glucose and CRP .
{ "id": "C0041004", "pos": [ 69, 82 ], "name": "triglycerides" }
{ "id": "C0017725", "pos": [ 85, 92 ], "name": "glucose" }
0NA
Risk factors include the severity of injury , wet clothing , low transport unit temperature , use of anesthesia , and prolonged surgery .
{ "id": "C3263722", "pos": [ 37, 43 ], "name": "injury" }
{ "id": "C0005903", "pos": [ 80, 91 ], "name": "temperature" }
0NA
According to MRI findings , 12/39 ( 30.7 % ) patients were positive for placenta accreta and 27/39 ( 69.3 % ) were negative .
{ "id": "C0024485", "pos": [ 13, 16 ], "name": "MRI" }
{ "id": "C0032044", "pos": [ 72, 88 ], "name": "placenta accreta" }
0NA
In conclusion , the developed MTX-UDLs-gel has a great potential for effective delivery of MTX into the inflamed joints in rheumatoid arthritis .
{ "id": "C0022417", "pos": [ 113, 119 ], "name": "joints" }
{ "id": "C0003873", "pos": [ 123, 143 ], "name": "rheumatoid arthritis" }
11finding_site_of
Endothelial progenitor cells ( EPCs ) are mobilized either from the bone marrow and/or the arterial to replace dysfunctional endothelial cells and rescue blood perfusion in ischemic tissues .
{ "id": "C0005953", "pos": [ 68, 79 ], "name": "bone marrow" }
{ "id": "C0003842", "pos": [ 91, 99 ], "name": "arterial" }
0NA
Cystoscopy and urinalysis did not reveal recurrence of the fistula .
{ "id": "C0016169", "pos": [ 59, 66 ], "name": "fistula" }
{ "id": "C0010702", "pos": [ 0, 10 ], "name": "Cystoscopy" }
0NA
Compared with pre-DBS scores , there were improvements in mean total UDRS score ( 15.3 % ) and in the following subscores : neck ( 18.18 % ) , trunk ( 32.9 % ) , arm ( 17.9 % ) , and leg ( 19.9 % ) .
{ "id": "C0023216", "pos": [ 183, 186 ], "name": "leg" }
{ "id": "C0027530", "pos": [ 124, 128 ], "name": "neck" }
0NA
In the 28 patients treated , 25 vertebral and 10 subclavian stents were placed .
{ "id": "C0038257", "pos": [ 60, 66 ], "name": "stents" }
{ "id": "C0549207", "pos": [ 32, 41 ], "name": "vertebral" }
0NA
In order to solve this issue , the diuretic effect of xipamide was assessed in healthy volunteers once without and once under strict water and salt restriction .
{ "id": "C0033213", "pos": [ 23, 28 ], "name": "issue" }
{ "id": "C0043047", "pos": [ 133, 138 ], "name": "water" }
0NA
In the other 5 patients the diagnosis of fatty herniation was made by computed tomography , which demonstrated the small diaphragmatic defect as well as the fatty nature of the mass .
{ "id": "C0577559", "pos": [ 177, 181 ], "name": "mass" }
{ "id": "C0040405", "pos": [ 70, 89 ], "name": "computed tomography" }
0NA
At endoscopic retrograde cholangiopancreatography , a cystic lesion within the head of the pancreas was filled with contrast from the normal pancreatic duct .
{ "id": "C0030274", "pos": [ 91, 99 ], "name": "pancreas" }
{ "id": "C0008310", "pos": [ 3, 49 ], "name": "endoscopic retrograde cholangiopancreatography" }
9direct_procedure_site_of
We report on a newborn boy manifesting an osteochondrodysplasia associated with fatal respiratory insufficiency who had normal lung volumes and extremity lengths .
{ "id": "C0015385", "pos": [ 144, 153 ], "name": "extremity" }
{ "id": "C0024109", "pos": [ 127, 131 ], "name": "lung" }
0NA
It extends transversely across the posterior abdominal wall from the duodenum to the spleen .
{ "id": "C0013303", "pos": [ 69, 77 ], "name": "duodenum" }
{ "id": "C0230194", "pos": [ 35, 59 ], "name": "posterior abdominal wall" }
0NA
Models of cancer-induced neuropathy are designed by injecting cancer cells near the peripheral nerves .
{ "id": "C0031119", "pos": [ 84, 101 ], "name": "peripheral nerves" }
{ "id": "C0475806", "pos": [ 75, 79 ], "name": "near" }
0NA
The triad of brain oedema , lung oedema and a distended urinary bladder on PMCT was highly specific for drug-associated cases of death .
{ "id": "C0005682", "pos": [ 56, 71 ], "name": "urinary bladder" }
{ "id": "C0034063", "pos": [ 28, 39 ], "name": "lung oedema" }
0NA
We present a patient who suffered from bowel obstruction and eventually perforation of the duodenum and discuss associated imaging findings .
{ "id": "C0549099", "pos": [ 72, 83 ], "name": "perforation" }
{ "id": "C0011923", "pos": [ 123, 130 ], "name": "imaging" }
0NA
In this study , rabbit isolated hearts with spontaneously increased LV mass were used to evaluate the effect of such LV alteration on ischemia detection criteria and performance .
{ "id": "C0018787", "pos": [ 32, 38 ], "name": "hearts" }
{ "id": "C0455825", "pos": [ 68, 75 ], "name": "LV mass" }
0NA
We performed a retrospective review of all patients undergoing simultaneous biliary and duodenal self-expandable metal stent placement between November 98 and May 2001 .
{ "id": "C0013303", "pos": [ 88, 96 ], "name": "duodenal" }
{ "id": "C0021107", "pos": [ 125, 134 ], "name": "placement" }
0NA
Endothelin-1 caused marked constriction of retinal vessels and pallor of the optic nerve head .
{ "id": "C0029127", "pos": [ 77, 93 ], "name": "optic nerve head" }
{ "id": "C0035330", "pos": [ 43, 58 ], "name": "retinal vessels" }
0NA
Treatment of rhEPO effectively suppressed fibrosis in CCl(4)-induced liver fibrosis mice models .
{ "id": "C0016059", "pos": [ 42, 50 ], "name": "fibrosis" }
{ "id": "C0239946", "pos": [ 69, 83 ], "name": "liver fibrosis" }
3associated_morphology_of
This effect was blocked by both the specific beta 1 blocker bisoprolol and the peptide P0-beta .
{ "id": "C0028778", "pos": [ 16, 23 ], "name": "blocked" }
{ "id": "C0053799", "pos": [ 60, 70 ], "name": "bisoprolol" }
0NA
Although the risk estimates were increased for overall tumours , breast tumours , malignant gynaecological tumours , and malignant melanoma , these associations were not statistically significant .
{ "id": "C0027651", "pos": [ 55, 62 ], "name": "tumours" }
{ "id": "C1458155", "pos": [ 65, 79 ], "name": "breast tumours" }
3associated_morphology_of
Two of the Alagille 's patients had histologic findings suggestive of membranous nephropathy and special stains revealed accumulation of lipid in the glomerular and tubular basement membranes .
{ "id": "C0022663", "pos": [ 150, 160 ], "name": "glomerular" }
{ "id": "C0017665", "pos": [ 70, 92 ], "name": "membranous nephropathy" }
11finding_site_of
Injections of APB into the turtle 's eye reduced or blocked the injected eye 's ability to drive horizontal optokinetic nystagmus , as also observed in rabbit and cat ( Knapp et al. , 1988 ; Yucel et al. , 1989 ) .
{ "id": "C0028778", "pos": [ 52, 59 ], "name": "blocked" }
{ "id": "C0021485", "pos": [ 0, 10 ], "name": "Injections" }
0NA
Corneal , conjunctival , and CL fitting variables were assessed prior to sleep , after a single night of CL wear , at 1 , 2 , and 4 hours after waking by clinicians who were masked to group membership .
{ "id": "C0009758", "pos": [ 10, 22 ], "name": "conjunctival" }
{ "id": "C0010031", "pos": [ 0, 7 ], "name": "Corneal" }
0NA
End-to-side anastomosis with ligation of the fistula in continuity has also been advocated .
{ "id": "C0016169", "pos": [ 45, 52 ], "name": "fistula" }
{ "id": "C0023690", "pos": [ 29, 37 ], "name": "ligation" }
0NA
We aim to compare the novel thienopyridine prasugrel versus double-dose clopidogrel in patients with HTPR and explore the interaction between CYP2C19 genotype and both drugs .
{ "id": "C0013227", "pos": [ 168, 173 ], "name": "drugs" }
{ "id": "C0037420", "pos": [ 122, 133 ], "name": "interaction" }
0NA
PLP was assessed daily during their postoperative hospital stay and at the last follow-up visit 60   days after operation .
{ "id": "C0034266", "pos": [ 0, 3 ], "name": "PLP" }
{ "id": "C0543467", "pos": [ 112, 121 ], "name": "operation" }
0NA
Clinically , splenomegaly alone or in combination with hepatomegaly was associated with a positive anti-HCV ( p = 0.04 and 0.01 respectively ) .
{ "id": "C1446409", "pos": [ 90, 98 ], "name": "positive" }
{ "id": "C0019209", "pos": [ 55, 67 ], "name": "hepatomegaly" }
0NA
These characteristics , if proven in vivo , may be beneficial for the treatment of overactive bladder , as increased bladder capacity with a negligible effect on voiding contractions may be anticipated .
{ "id": "C0005682", "pos": [ 117, 124 ], "name": "bladder" }
{ "id": "C0878773", "pos": [ 83, 101 ], "name": "overactive bladder" }
11finding_site_of
Classical inflammatory mediators such as bradykinin have been shown to sensitize nociceptors for both itch and pain .
{ "id": "C0006100", "pos": [ 41, 51 ], "name": "bradykinin" }
{ "id": "C0033774", "pos": [ 102, 106 ], "name": "itch" }
0NA
In zoster , but not in varicella eruption or HSV infections , follicular involvement was unaccompanied by marked changes in the epidermal surface .
{ "id": "C0019360", "pos": [ 3, 9 ], "name": "zoster" }
{ "id": "C0008049", "pos": [ 23, 32 ], "name": "varicella" }
18occurs_after
In the present study , we investigated the role of low-density lipoprotein receptor-related protein-1 in heme removal and neuroprotection in a mouse model of intracerebral hemorrhage .
{ "id": "C0015252", "pos": [ 110, 117 ], "name": "removal" }
{ "id": "C0018966", "pos": [ 105, 109 ], "name": "heme" }
0NA
The manipulations that decrease NO production may have therapeutic potential in preserving intestinal mucosal integrity in sepsis .
{ "id": "C0021853", "pos": [ 91, 101 ], "name": "intestinal" }
{ "id": "C0026724", "pos": [ 102, 109 ], "name": "mucosal" }
0NA
A careful and thorough dissection was carried out to isolate the entire lacrimal drainage system from the punctum to the nasolacrimal duct .
{ "id": "C0459434", "pos": [ 72, 96 ], "name": "lacrimal drainage system" }
{ "id": "C0012737", "pos": [ 23, 33 ], "name": "dissection" }
0NA
Primary percutaneous transluminal coronary angioplasty is an attractive method for reopening occluded coronary arteries .
{ "id": "C0205042", "pos": [ 102, 119 ], "name": "coronary arteries" }
{ "id": "C2936173", "pos": [ 8, 54 ], "name": "percutaneous transluminal coronary angioplasty" }
9direct_procedure_site_of
Loss of retinal ganglion cells ( RGCs ) during retinal ischemia is the potentially blinding mechanism that underlies several sight-threatening disorders .
{ "id": "C0035298", "pos": [ 47, 54 ], "name": "retinal" }
{ "id": "C0022116", "pos": [ 55, 63 ], "name": "ischemia" }
0NA
Corneas diagnosed with ICE syndrome and removed during corneal transplantation were freshly frozen , sectioned , and stained with monoclonal antibodies to keratin subgroups , vimentin , desmin , and a series of other antibodies against intermediate filaments .
{ "id": "C0010031", "pos": [ 0, 7 ], "name": "Corneas" }
{ "id": "C0010042", "pos": [ 55, 78 ], "name": "corneal transplantation" }
9direct_procedure_site_of
Hindfoot alignment can affect the weight-bearing kinematics of the knee joint in patients undergoing total knee arthroplasty ( TKA ) .
{ "id": "C0022745", "pos": [ 67, 77 ], "name": "knee joint" }
{ "id": "C0086511", "pos": [ 101, 124 ], "name": "total knee arthroplasty" }
9direct_procedure_site_of
These effects were strongly blocked by bicuculline ( 10 microM ) , but not by GABA(B ) antagonist and strychnine , and completely maintained under the blockage of synaptic transmission .
{ "id": "C0028778", "pos": [ 28, 35 ], "name": "blocked" }
{ "id": "C0038479", "pos": [ 102, 112 ], "name": "strychnine" }
0NA
Despite endoscopic nasobiliary drainage , plasma exchange , and continuous hemodiafiltration , he died of hepatic failure after 5 days .
{ "id": "C0011065", "pos": [ 98, 102 ], "name": "died" }
{ "id": "C0085605", "pos": [ 106, 121 ], "name": "hepatic failure" }
0NA
Two malaria parasites , Plasmodium vivax and Plasmodium knowlesi , use DARC to trigger internalization into red blood cells .
{ "id": "C0024530", "pos": [ 4, 11 ], "name": "malaria" }
{ "id": "C0014772", "pos": [ 108, 123 ], "name": "red blood cells" }
0NA
Phototoxicity assessment of ten different lipsticks and eight facial creams was conducted .
{ "id": "C0031809", "pos": [ 14, 24 ], "name": "assessment" }
{ "id": "C0162830", "pos": [ 0, 13 ], "name": "Phototoxicity" }
0NA
Budd Chiari syndrome ( BCS ) is a heterogeneous group of disorders characterized by hepatic venous outflow obstruction at any level from the small hepatic veins to the atrio cava junction .
{ "id": "C0019155", "pos": [ 147, 160 ], "name": "hepatic veins" }
{ "id": "C0019154", "pos": [ 0, 20 ], "name": "Budd Chiari syndrome" }
11finding_site_of
Temperature differences from baseline reached statistical significance at T30 min after endotoxin administration ( 15 min after completing the study medication infusion ) .
{ "id": "C0574032", "pos": [ 160, 168 ], "name": "infusion" }
{ "id": "C0005903", "pos": [ 0, 11 ], "name": "Temperature" }
0NA
Treatment of the underlying malignant neoplasm and relief of the obstruction produce prompt improvement in the dermatologic findings .
{ "id": "C0028778", "pos": [ 65, 76 ], "name": "obstruction" }
{ "id": "C0006826", "pos": [ 28, 46 ], "name": "malignant neoplasm" }
0NA
The greatest growth was seen in computed tomography and computed tomographic angiography , which rose from 99.4 examinations in 1996 to 239.3 in 2005 ( + 141 % ) .
{ "id": "C0031809", "pos": [ 112, 124 ], "name": "examinations" }
{ "id": "C0040405", "pos": [ 32, 51 ], "name": "computed tomography" }
0NA
This is particularly important for lung cancer given the proximity of the lung , heart , esophagus , major airways , large blood vessels , and spinal cord .
{ "id": "C0024109", "pos": [ 74, 78 ], "name": "lung" }
{ "id": "C0242379", "pos": [ 35, 46 ], "name": "lung cancer" }
11finding_site_of
Bladder tissues were harvested from dogs and patients at the end of instillation .
{ "id": "C0005682", "pos": [ 0, 7 ], "name": "Bladder" }
{ "id": "C0040300", "pos": [ 8, 15 ], "name": "tissues" }
0NA

Dataset Card for MedDistant19

Dataset Summary

MedDistant19 is a distantly supervised biomedical relation extraction (Bio-DSRE) corpus obtained by aligning the PubMed MEDLINE abstracts from 2019 with the SNOMED-CT knowledge graph (KG) derived from the UMLS Metathesaurus 2019. For more details, please refer to the paper: https://aclanthology.org/2022.coling-1.198/

Before Downloading: To use this data, you must have signed the UMLS agreement. The UMLS agreement requires those who use the UMLS to file a brief report once a year to summarize their use of the UMLS. It also requires the acknowledgment that the UMLS contains copyrighted material and that those copyright restrictions be respected. The UMLS agreement requires users to agree to obtain agreements for EACH copyrighted source prior to its use within a commercial or production application. See https://www.nlm.nih.gov/databases/umls.html

Languages

The language in the dataset is English.

Dataset Structure

Data Instances

An example of 'train' looks as follows:

{
    "text": "Urethral stones are rarely formed primarily in the urethra and are usually associated with urethral strictures or diverticula .", 
    "h": {"id": "C0041967", "pos": [51, 58], "name": "urethra"}, 
    "t": {"id": "C0041974", "pos": [91, 110], "name": "urethral strictures"}, 
    "relation": "finding_site_of"
}

Data Fields

  • text: the text of this example, a string feature.
  • h: head entity
    • id: identifier of the head entity, a string feature.
    • pos: character offsets of the head entity, a list of int32 features.
    • name: head entity text, a string feature.
  • t: tail entity
    • id: identifier of the tail entity, a string feature.
    • pos: character offsets of the tail entity, a list of int32 features.
    • name: tail entity text, a string feature.
  • relation: a class label.

Dataset Creation

Curation Rationale

[More Information Needed]

Source Data

Data Collection and Processing

[More Information Needed]

Who are the source data producers?

[More Information Needed]

Annotation process

[More Information Needed]

Who are the annotators?

[More Information Needed]

Personal and Sensitive Information

[More Information Needed]

Bias, Risks, and Limitations

[More Information Needed]

Recommendations

Users should be made aware of the risks, biases and limitations of the dataset. More information needed for further recommendations.

Citation

BibTeX:

@inproceedings{amin-etal-2022-meddistant19,
    title = "{M}ed{D}istant19: Towards an Accurate Benchmark for Broad-Coverage Biomedical Relation Extraction",
    author = "Amin, Saadullah and Minervini, Pasquale and Chang, David and Stenetorp, Pontus and Neumann, G{\"u}nter",
    booktitle = "Proceedings of the 29th International Conference on Computational Linguistics",
    month = oct,
    year = "2022",
    address = "Gyeongju, Republic of Korea",
    publisher = "International Committee on Computational Linguistics",
    url = "https://aclanthology.org/2022.coling-1.198",
    pages = "2259--2277",
}

APA:

Amin, S., Minervini, P., Chang, D., Stenetorp, P., & Neumann, G. (2022). Meddistant19: towards an accurate benchmark for broad-coverage biomedical relation extraction. arXiv preprint arXiv:2204.04779.

Dataset Card Authors

@phucdev

Dataset Card Contact

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