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The male sibling developed heart failure and severe hypertension , and died at the age of 6 weeks despite of treatment with bisphosphonates , ACE inhibitors , and hydralazine . | {
"id": "C0020223",
"pos": [
163,
174
],
"name": "hydralazine"
} | {
"id": "C0020538",
"pos": [
52,
64
],
"name": "hypertension"
} | 0NA
|
The alpha B-crystallin polypeptide , a functional member of the small heat shock family , is expressed in many tissues in a developmentally regulated fashion , is stress-inducible , and is overexpressed in many degenerative diseases and some tumors indicating that it plays multiple roles . | {
"id": "C0027651",
"pos": [
242,
248
],
"name": "tumors"
} | {
"id": "C0040300",
"pos": [
111,
118
],
"name": "tissues"
} | 0NA
|
Of all studied parameters , only chronic white matter supratentorial lesions present on brain MRI negatively correlated with clinical recovery ( Phi coefficient=-0.637 , p=0.001 ) . | {
"id": "C0006104",
"pos": [
88,
93
],
"name": "brain"
} | {
"id": "C0024485",
"pos": [
94,
97
],
"name": "MRI"
} | 0NA
|
Control of blood pressure can be a problem for intracranial procedures . | {
"id": "C0033213",
"pos": [
35,
42
],
"name": "problem"
} | {
"id": "C0005823",
"pos": [
11,
25
],
"name": "blood pressure"
} | 0NA
|
In addition , combating newly emerging diseases in human as well as animal healthcare is challenging and is dependent on developing safe and efficient diagnostics . | {
"id": "C0429964",
"pos": [
108,
117
],
"name": "dependent"
} | {
"id": "C0012634",
"pos": [
39,
47
],
"name": "diseases"
} | 0NA
|
In vivo , A(3)AR agonists act as cardio- and neuroprotective agents and attenuate ischemic damage . | {
"id": "C0010957",
"pos": [
91,
97
],
"name": "damage"
} | {
"id": "C0018787",
"pos": [
33,
40
],
"name": "cardio-"
} | 0NA
|
Helicobacter pylori arginase is an important factor in evasion of the host 's immune system and contributes to persistent infection by this bacterium . | {
"id": "C0003762",
"pos": [
20,
28
],
"name": "arginase"
} | {
"id": "C0009450",
"pos": [
122,
131
],
"name": "infection"
} | 0NA
|
In PD , ERC atrophy , as measured on MRI , however , has received less attention , compared to hippocampal atrophy . | {
"id": "C0333641",
"pos": [
12,
19
],
"name": "atrophy"
} | {
"id": "C0024485",
"pos": [
37,
40
],
"name": "MRI"
} | 0NA
|
A statistically significant correlation between stoma diameter and emptying rate was seen 1 year after gastroplasty but not after gastric bypass . | {
"id": "C1955856",
"pos": [
48,
53
],
"name": "stoma"
} | {
"id": "C0017125",
"pos": [
130,
144
],
"name": "gastric bypass"
} | 0NA
|
Although cultures can be established from thawed infected erythrocytes , the plating efficiency is relatively low . | {
"id": "C0407295",
"pos": [
77,
84
],
"name": "plating"
} | {
"id": "C0014772",
"pos": [
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70
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"name": "erythrocytes"
} | 0NA
|
Extensive research has revealed a complex regulatory network that senses and responds to a myriad of host- and microbiota-derived signals in the infected gut to control transcription of the LEE . | {
"id": "C0017189",
"pos": [
154,
157
],
"name": "gut"
} | {
"id": "C0036658",
"pos": [
66,
72
],
"name": "senses"
} | 0NA
|
These symptoms were treated successfully with acetaminophen and/or diphenhydramine . | {
"id": "C0000970",
"pos": [
46,
59
],
"name": "acetaminophen"
} | {
"id": "C0012522",
"pos": [
67,
82
],
"name": "diphenhydramine"
} | 0NA
|
This malignant neoplasm is a member of the peripheral primitive neuroectodermal tumor ( PPNET ) family and typically involves the periosteum , soft tissue , and extrapulmonary tissue of the thoracic wall . | {
"id": "C0205076",
"pos": [
190,
203
],
"name": "thoracic wall"
} | {
"id": "C0006826",
"pos": [
5,
23
],
"name": "malignant neoplasm"
} | 0NA
|
At the time of the outpatient follow-up appointment , the patient had no signs of thrombosis or bleeding complications . | {
"id": "C0019080",
"pos": [
96,
104
],
"name": "bleeding"
} | {
"id": "C0040053",
"pos": [
82,
92
],
"name": "thrombosis"
} | 0NA
|
To investigate associations of very early age-related macular degeneration ( AMD ) with daily intake of vitamin A , beta-carotene , vitamin E , vitamin C , zinc and copper and interactions with AMD-associated polymorphisms in complement factor H ( CFHY402H ) and ARMS2/LOC387715 . | {
"id": "C0003968",
"pos": [
144,
153
],
"name": "vitamin C"
} | {
"id": "C0242383",
"pos": [
42,
74
],
"name": "age-related macular degeneration"
} | 0NA
|
At the end of the follow-up period , successful closure occurred 91.7 % and 84.6 % patients in the OC and control groups , respectively ( p>0.05 ) . | {
"id": "C0185003",
"pos": [
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55
],
"name": "closure"
} | {
"id": "C0025344",
"pos": [
28,
34
],
"name": "period"
} | 0NA
|
Eight pesticides were tested in a bioassay based on the induction of preneoplastic lesions in the liver . | {
"id": "C0221198",
"pos": [
83,
90
],
"name": "lesions"
} | {
"id": "C0023884",
"pos": [
98,
103
],
"name": "liver"
} | 0NA
|
A significant number of investigational drugs are now being tested in humans , with a main focus on cardiovascular diseases , such as congestive heart failure and pulmonary hypertension . | {
"id": "C0013227",
"pos": [
40,
45
],
"name": "drugs"
} | {
"id": "C0018802",
"pos": [
134,
158
],
"name": "congestive heart failure"
} | 0NA
|
Three infants had a dramatic improvement in systemic arterial oxygen saturation associated with dilation of the ductus arteriosus ; in two of the three cases urgent surgery was avoided . | {
"id": "C0012359",
"pos": [
96,
104
],
"name": "dilation"
} | {
"id": "C0428175",
"pos": [
53,
79
],
"name": "arterial oxygen saturation"
} | 0NA
|
Body mass index , glucose , sex , rs328 and rs7007797 in LPL , rs662799 and rs3135506 in APOA5 , and rs1260326 in GCKR explained 36 % of the variability in plasma triglycerides , 7.3 % of which was attributable to the genetic variables . | {
"id": "C0041004",
"pos": [
163,
176
],
"name": "triglycerides"
} | {
"id": "C0017725",
"pos": [
18,
25
],
"name": "glucose"
} | 0NA
|
False-negative test results in hypercortisolism could occur when [ cortisol ] is outside of the individual 's HSP and within the reference interval . | {
"id": "C0020268",
"pos": [
67,
75
],
"name": "cortisol"
} | {
"id": "C0001622",
"pos": [
31,
47
],
"name": "hypercortisolism"
} | 0NA
|
We analyzed all 104 fistulas created in all 68 patients who underwent hemodialysis during October 1993 at the St. Joseph General Teaching Hospital , Veldhoven , The Netherlands . | {
"id": "C0016169",
"pos": [
20,
28
],
"name": "fistulas"
} | {
"id": "C0019004",
"pos": [
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82
],
"name": "hemodialysis"
} | 0NA
|
The relation between brain activity and the immune system was evaluated by assessing immune responses in 20 healthy women who manifested extreme differences in the asymmetry of frontal cortex activation . | {
"id": "C0020962",
"pos": [
44,
57
],
"name": "immune system"
} | {
"id": "C0301872",
"pos": [
85,
101
],
"name": "immune responses"
} | 0NA
|
In the early part of the review we discuss how escalations of dose of chemoradiotherapy might allow ablation of both marrow-derived ( leukaemia ) and non-marrow-derived disease ( lymphoma and solid tumour ) provided that haemopoiesis is reintroduced into the host in the form of autologous marrow stem cells , and how cryopreservation techniques have allowed this to proceed . | {
"id": "C0547070",
"pos": [
100,
108
],
"name": "ablation"
} | {
"id": "C0023418",
"pos": [
134,
143
],
"name": "leukaemia"
} | 0NA
|
By the use of probes p114.12 , p482.6 , and DX 13 , almost 98 % of all the informative females could be detected . | {
"id": "C0442726",
"pos": [
104,
112
],
"name": "detected"
} | {
"id": "C0182400",
"pos": [
14,
20
],
"name": "probes"
} | 0NA
|
Since lymphocytes circulating through the body and residing in the lymph nodes have different properties , it is important to examine both locations . | {
"id": "C0024204",
"pos": [
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78
],
"name": "lymph nodes"
} | {
"id": "C0227230",
"pos": [
42,
46
],
"name": "body"
} | 0NA
|
Three distinct pathways ascend from the torus semicircularis to the telencephalon ; they course through either 1 ) the lateral preglomerular nucleus of the posterior tuberculum , 2 ) the anterior tuberal nucleus of the hypothalamus , or 3 ) the central posterior nucleus of the dorsal thalamus . | {
"id": "C0039729",
"pos": [
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293
],
"name": "dorsal thalamus"
} | {
"id": "C0039452",
"pos": [
68,
81
],
"name": "telencephalon"
} | 0NA
|
Various techniques have been described to correct the disorder by either reefing the sagittal fibers or using a slip of extensor tendon around the radial collateral ligament . | {
"id": "C0012634",
"pos": [
54,
62
],
"name": "disorder"
} | {
"id": "C0224849",
"pos": [
120,
135
],
"name": "extensor tendon"
} | 0NA
|
The present study suggests that in infectious CNS diseases an elevated IgG-Index might be an additional marker for the early identification of patients at risk for neurological morbidity . | {
"id": "C1301721",
"pos": [
164,
186
],
"name": "neurological morbidity"
} | {
"id": "C0009450",
"pos": [
35,
45
],
"name": "infectious"
} | 0NA
|
LncRNAs involve in the osteogenic differentiation of bone marrow and dental tissuederived mesenchymal stem cells , and they could become promising therapeutic targets and prognosis parameters . | {
"id": "C0005953",
"pos": [
53,
64
],
"name": "bone marrow"
} | {
"id": "C0033325",
"pos": [
171,
180
],
"name": "prognosis"
} | 0NA
|
Otofaciocervical syndrome ( OFCS ) is an autosomal recessively inherited disorder characterized by facial dysmorphism , external ear anomalies with preauricular pits and hearing impairment , branchial cysts or fistulas , anomalies of the vertebrae and the shoulder girdle , and mild intellectual disability . | {
"id": "C1384666",
"pos": [
170,
188
],
"name": "hearing impairment"
} | {
"id": "C0016169",
"pos": [
210,
218
],
"name": "fistulas"
} | 0NA
|
There is evidence to suggest that Crohn disease is caused by an immunologic response to an unknown intestinal luminal antigen , probably of bacterial origin . | {
"id": "C0010346",
"pos": [
34,
47
],
"name": "Crohn disease"
} | {
"id": "C0021853",
"pos": [
99,
109
],
"name": "intestinal"
} | 0NA
|
All three treatments reduced hippocampal morphologic correlates of brain aging ( neuronal loss , glial reactivity ) . | {
"id": "C0006104",
"pos": [
67,
72
],
"name": "brain"
} | {
"id": "C0019564",
"pos": [
29,
40
],
"name": "hippocampal"
} | 0NA
|
Optical microweighing sensors are an essential component of micro-force measurements in physical , chemical , and biological detection fields , although , their limited detection range ( less than 15 ° ) severely hinders their wide application . | {
"id": "C0031809",
"pos": [
88,
96
],
"name": "physical"
} | {
"id": "C0185125",
"pos": [
232,
243
],
"name": "application"
} | 0NA
|
In clinical practice there is always the risk of encountering laryngospasm , which is defined as the occlusion of the glottis by the action of the intrinsic laryngeal muscles . | {
"id": "C0017681",
"pos": [
118,
125
],
"name": "glottis"
} | {
"id": "C0023066",
"pos": [
62,
74
],
"name": "laryngospasm"
} | 0NA
|
Insulin is also necessary for the maintenance of normal rates of glucose oxidation and storage in insulin-sensitive tissues and for the prevention of excessive gluconeogenic substrate production . | {
"id": "C0199176",
"pos": [
136,
146
],
"name": "prevention"
} | {
"id": "C0021641",
"pos": [
0,
7
],
"name": "Insulin"
} | 0NA
|
Mice inoculated with microfilariae of the filarial nematode Onchocerca lienalis clear their parasites from the skin over a period of 3 to 4 months and are highly resistant to a challenge infection . | {
"id": "C0009450",
"pos": [
187,
196
],
"name": "infection"
} | {
"id": "C0444099",
"pos": [
111,
115
],
"name": "skin"
} | 0NA
|
These findings indicated that mPEG2000-PLA modified microemulsion improved drug entry into blood and brain compared with normal microemulsion : the introduction of mPEG2000-PLA in microemulsion resulted in brain-targeting enhancement of both fat-soluble and water-soluble drugs . | {
"id": "C0005767",
"pos": [
91,
96
],
"name": "blood"
} | {
"id": "C0006104",
"pos": [
101,
106
],
"name": "brain"
} | 0NA
|
Both nilvadipine and nifedipine significantly decreased blood pressure in SHRSP . | {
"id": "C0028066",
"pos": [
21,
31
],
"name": "nifedipine"
} | {
"id": "C0005823",
"pos": [
56,
70
],
"name": "blood pressure"
} | 0NA
|
The change of temperature had no evident influence on removal effect of COD . | {
"id": "C0015252",
"pos": [
54,
61
],
"name": "removal"
} | {
"id": "C0005903",
"pos": [
14,
25
],
"name": "temperature"
} | 0NA
|
The study provides a scientific basis for the screening and selection of probiotics that compete with selective groups of pathogens for adhesion to intestinal surfaces . | {
"id": "C0021853",
"pos": [
148,
158
],
"name": "intestinal"
} | {
"id": "C0199230",
"pos": [
46,
55
],
"name": "screening"
} | 0NA
|
In this large UK population-based study , no significant associations were observed for post-diagnostic use of statins , β-blockers or low-dose aspirin and EC survival . | {
"id": "C0004057",
"pos": [
144,
151
],
"name": "aspirin"
} | {
"id": "C0360714",
"pos": [
111,
118
],
"name": "statins"
} | 0NA
|
There are many complications associated with oral anticoagulation in the prevention of stroke related to atrial fibrillation . | {
"id": "C0199176",
"pos": [
73,
83
],
"name": "prevention"
} | {
"id": "C0038454",
"pos": [
87,
93
],
"name": "stroke"
} | 0NA
|
We have previously reported that interferon-alpha ( IFN-alpha ) and tumor necrosis factor-alpha ( TNF-alpha ) blocked the cell cycle progression of cancer cells at the S to G2 transition , causing a synergistic antitumor effect . | {
"id": "C0028778",
"pos": [
110,
117
],
"name": "blocked"
} | {
"id": "C0002199",
"pos": [
33,
49
],
"name": "interferon-alpha"
} | 0NA
|
This is the first reported case of chimney technique used to exclude a celiac artery aneurysm , with a clinical suspicion of infectious etiology , preserving celiac artery patency . | {
"id": "C0007569",
"pos": [
158,
171
],
"name": "celiac artery"
} | {
"id": "C0264969",
"pos": [
71,
93
],
"name": "celiac artery aneurysm"
} | 11finding_site_of
|
Autopsy revealed no pathologic findings in the heart or in the extra- or intracranial arteries . | {
"id": "C0018787",
"pos": [
47,
52
],
"name": "heart"
} | {
"id": "C0004398",
"pos": [
0,
7
],
"name": "Autopsy"
} | 0NA
|
In vitro studies suggested that the release of PPS was dependent on the initial drug loading and the composition of the PEC . | {
"id": "C0013227",
"pos": [
80,
84
],
"name": "drug"
} | {
"id": "C0265259",
"pos": [
47,
50
],
"name": "PPS"
} | 0NA
|
Survey of over 100 individuals infected with HIV revealed a nonrandom distribution of seropositivity against trs : a few of the asymptomatic carriers and AIDS patients ( less than 5 % ) had sera that reacted with the 26-kD protein . | {
"id": "C0033684",
"pos": [
223,
230
],
"name": "protein"
} | {
"id": "C0001175",
"pos": [
154,
158
],
"name": "AIDS"
} | 0NA
|
Most of the established antidiabetes therapies ( eg , sulfonylureas , thiazolidinediones ) promote weight gain , thereby exacerbating insulin resistance and glucose intolerance . | {
"id": "C0043094",
"pos": [
99,
110
],
"name": "weight gain"
} | {
"id": "C0271650",
"pos": [
157,
176
],
"name": "glucose intolerance"
} | 0NA
|
CSF examination revealed albuminocytologic dissociation in 25.0 % and NCS was abnormal in 61.8 % . | {
"id": "C0205161",
"pos": [
78,
86
],
"name": "abnormal"
} | {
"id": "C0031809",
"pos": [
4,
15
],
"name": "examination"
} | 0NA
|
Few studies have examined the behavioral and clinical indicators of sleep difficulty among older African Americans diagnosed with arthritis . | {
"id": "C1299586",
"pos": [
74,
84
],
"name": "difficulty"
} | {
"id": "C0037313",
"pos": [
68,
73
],
"name": "sleep"
} | 0NA
|
An eye-movement monitoring experiment was carried out to examine the effects of the difficulty of the problem ( simple versus complex problems ) and the type of figure ( figure 1 or figure 4 ) on the time course of processing categorical syllogisms . | {
"id": "C1299586",
"pos": [
84,
94
],
"name": "difficulty"
} | {
"id": "C0150369",
"pos": [
16,
26
],
"name": "monitoring"
} | 0NA
|
For stage I yolk sac tumor of testis in children younger than 2 years , high inguinal orchiectomy alone has been the standard treatment , with a cure rate of at least 75 % . | {
"id": "C0039597",
"pos": [
30,
36
],
"name": "testis"
} | {
"id": "C0029189",
"pos": [
86,
97
],
"name": "orchiectomy"
} | 9direct_procedure_site_of
|
The steroid ( 6-methylene-progesterone , MEP ) gives irreversible inhibition of ovarian 5 alpha-reductase activity in vitro with testosterone as well as progesterone as substrate . | {
"id": "C0039601",
"pos": [
129,
141
],
"name": "testosterone"
} | {
"id": "C0033308",
"pos": [
153,
165
],
"name": "progesterone"
} | 0NA
|
He concluded that ether was not a useful substance for analgesia during vaginal delivery , since it disturbed the natural course of labour . | {
"id": "C0014994",
"pos": [
18,
23
],
"name": "ether"
} | {
"id": "C0002766",
"pos": [
55,
64
],
"name": "analgesia"
} | 0NA
|
The thrombi as well as the neovascularizations underwent near-complete resolution with 4 weeks ' anticoagulation therapy with warfarin maintaining an international normalization ratio of 3.5 . | {
"id": "C0087086",
"pos": [
4,
11
],
"name": "thrombi"
} | {
"id": "C0043031",
"pos": [
126,
134
],
"name": "warfarin"
} | 0NA
|
The modulation of renal organic anion transport may be another aspect of Cd2 + nephrotoxicity . | {
"id": "C0022646",
"pos": [
18,
23
],
"name": "renal"
} | {
"id": "C0595916",
"pos": [
79,
93
],
"name": "nephrotoxicity"
} | 11finding_site_of
|
This study showed that , in pwMS , the time taken to recover from feelings of leg fatigue increased with the intensity of the exercise session rather that total work performed and was related to increase in body temperature . | {
"id": "C0023216",
"pos": [
78,
81
],
"name": "leg"
} | {
"id": "C0005903",
"pos": [
207,
223
],
"name": "body temperature"
} | 0NA
|
Anal resting pressure decreased significantly after low anterior resection and did not recover in the course of the first year after operation . | {
"id": "C0015252",
"pos": [
65,
74
],
"name": "resection"
} | {
"id": "C0543467",
"pos": [
133,
142
],
"name": "operation"
} | 0NA
|
Noninvasive techniques for measurement of tissue pH can be invaluable in assessing disease extent and response to therapy in a variety of pathological conditions , such as renal acidosis and alkalosis , and cancers . | {
"id": "C0006826",
"pos": [
207,
214
],
"name": "cancers"
} | {
"id": "C0012634",
"pos": [
83,
90
],
"name": "disease"
} | 0NA
|
Adventitia would be involved in a physiological mechanism of arterial wall viscous and elastic properties regulation , that could influence arterial buffering and conduit functions . | {
"id": "C0003842",
"pos": [
140,
148
],
"name": "arterial"
} | {
"id": "C0507850",
"pos": [
61,
74
],
"name": "arterial wall"
} | 0NA
|
The modulation of expression was most pronounced in bronchioles but was also present in the bronchi and trachea . | {
"id": "C0006255",
"pos": [
92,
99
],
"name": "bronchi"
} | {
"id": "C0006270",
"pos": [
52,
63
],
"name": "bronchioles"
} | 0NA
|
It is unclear as to whether the abnormal ventricular function may serve as a marker for future development of dilated cardiomyopathy . | {
"id": "C0205161",
"pos": [
32,
40
],
"name": "abnormal"
} | {
"id": "C0007193",
"pos": [
110,
132
],
"name": "dilated cardiomyopathy"
} | 0NA
|
Preoperatively , all blood samples from the patients had negative Limulus amoebocyte lysate tests , negative blood cultures , normal total white cell counts , and were clinically without signs of infection . | {
"id": "C0178913",
"pos": [
21,
34
],
"name": "blood samples"
} | {
"id": "C0009450",
"pos": [
196,
205
],
"name": "infection"
} | 0NA
|
Only the patients with severe chronic medical problems were qualified for the treatment : 31 with the respiratory failure , 29 with the circulatory failure and 5 after the stroke with spastic hemiplegia . | {
"id": "C0038454",
"pos": [
172,
178
],
"name": "stroke"
} | {
"id": "C0036974",
"pos": [
136,
155
],
"name": "circulatory failure"
} | 0NA
|
Observations from cardiac catheterization suggest that coronary artery cross-sectional area ( CSA ) is increased in patients with left ventricular ( LV ) hypertrophy and is proportional to LV mass . | {
"id": "C0010592",
"pos": [
94,
97
],
"name": "CSA"
} | {
"id": "C0018795",
"pos": [
18,
41
],
"name": "cardiac catheterization"
} | 0NA
|
The drug caused severe birth defects . | {
"id": "C0013227",
"pos": [
4,
8
],
"name": "drug"
} | {
"id": "C0000768",
"pos": [
23,
36
],
"name": "birth defects"
} | 0NA
|
Different breathing exercises are recommended in different parts of the world , and there is no consensus about the most effective breathing technique after cardiac surgery . | {
"id": "C0006155",
"pos": [
10,
29
],
"name": "breathing exercises"
} | {
"id": "C0018821",
"pos": [
157,
172
],
"name": "cardiac surgery"
} | 0NA
|
Pedicles between T4 and T8 may not be wide enough for screw fixation . | {
"id": "C0185023",
"pos": [
60,
68
],
"name": "fixation"
} | {
"id": "C0005975",
"pos": [
54,
59
],
"name": "screw"
} | 0NA
|
The measurements on railway workers indicate a relationship between temperature and fatigue . | {
"id": "C0015672",
"pos": [
84,
91
],
"name": "fatigue"
} | {
"id": "C0005903",
"pos": [
68,
79
],
"name": "temperature"
} | 0NA
|
Whether the terminal drug half-life was prolonged or shortened , a biliary excretion reduction always increased the area under the plasma decay curve for intravenous and oral doses and also raised the steady-state drug level in the body for constant-rate intravenous infusion . | {
"id": "C0574032",
"pos": [
267,
275
],
"name": "infusion"
} | {
"id": "C0227230",
"pos": [
232,
236
],
"name": "body"
} | 0NA
|
Pain and swelling , which may lead to inhibition of the extensor mechanism and ultimately a delay in rehabilitation , are common complications of knee arthroscopy . | {
"id": "C0013604",
"pos": [
9,
17
],
"name": "swelling"
} | {
"id": "C0034991",
"pos": [
101,
115
],
"name": "rehabilitation"
} | 0NA
|
These cells play critical role in health and disease such as cancer and wound by Production of collagen , fibronectin , cytokines and growth factors . | {
"id": "C0006826",
"pos": [
61,
67
],
"name": "cancer"
} | {
"id": "C0012634",
"pos": [
45,
52
],
"name": "disease"
} | 0NA
|
Although interleukin (IL)-6 is known as a central regulator of the immune response in pneumonia , its regulation in the lung is widely unknown . | {
"id": "C0024109",
"pos": [
120,
124
],
"name": "lung"
} | {
"id": "C0032285",
"pos": [
86,
95
],
"name": "pneumonia"
} | 11finding_site_of
|
The antigen detected by S150 was found to be broadly represented on melanoma , glioma , renal cell carcinoma , neuroblastoma , and head and neck carcinoma cell lines . | {
"id": "C0018670",
"pos": [
131,
135
],
"name": "head"
} | {
"id": "C0025202",
"pos": [
68,
76
],
"name": "melanoma"
} | 0NA
|
A 59-year-old woman developed local recurrence of papillary thyroid carcinoma three years after FNA of the primary cancer . | {
"id": "C1510483",
"pos": [
96,
99
],
"name": "FNA"
} | {
"id": "C0238463",
"pos": [
50,
77
],
"name": "papillary thyroid carcinoma"
} | 0NA
|
Tilly 's group reported the existence of ovarian germline stem cells ( GSCs ) in postnatal ovaries of mice and suggested that the bone marrow could be an extragonadal source of ovarian GSCs . | {
"id": "C0029939",
"pos": [
91,
98
],
"name": "ovaries"
} | {
"id": "C0005953",
"pos": [
130,
141
],
"name": "bone marrow"
} | 0NA
|
Her hair was short , abundant , and stiff , her eyebrows were sparse , and her skin was dry . | {
"id": "C0015420",
"pos": [
48,
56
],
"name": "eyebrows"
} | {
"id": "C0018494",
"pos": [
4,
8
],
"name": "hair"
} | 0NA
|
All patients had a biopsy confirmed diagnosis of celiac disease . | {
"id": "C0005558",
"pos": [
19,
25
],
"name": "biopsy"
} | {
"id": "C0007570",
"pos": [
49,
63
],
"name": "celiac disease"
} | 0NA
|
A case of 55 years old male with recurrent melena is being presented , who was found to have scattered varices on small as well as large intestine . | {
"id": "C0021853",
"pos": [
137,
146
],
"name": "intestine"
} | {
"id": "C0042345",
"pos": [
103,
110
],
"name": "varices"
} | 0NA
|
It is suggested that activation of NK-1 receptors in the RVM and the ensuing sensitization of on cells may contribute to the development of central sensitization and hyperalgesia after tissue injury and inflammation . | {
"id": "C0021368",
"pos": [
203,
215
],
"name": "inflammation"
} | {
"id": "C0020429",
"pos": [
166,
178
],
"name": "hyperalgesia"
} | 0NA
|
Tail-cuff plethysmography was used to monitor the systolic blood pressure of all animals for 7 weeks post-clipping or sham operation . | {
"id": "C0543467",
"pos": [
123,
132
],
"name": "operation"
} | {
"id": "C0871470",
"pos": [
50,
73
],
"name": "systolic blood pressure"
} | 0NA
|
Handwashing practices , antibiotic prophylaxis are important , especially in the immunocompromised host . | {
"id": "C0085393",
"pos": [
81,
98
],
"name": "immunocompromised"
} | {
"id": "C0282638",
"pos": [
24,
46
],
"name": "antibiotic prophylaxis"
} | 0NA
|
Due to the anatomic complexity of the cauda equina , a complete resection can be technically challenging in this region . | {
"id": "C0015252",
"pos": [
64,
73
],
"name": "resection"
} | {
"id": "C0007458",
"pos": [
38,
50
],
"name": "cauda equina"
} | 0NA
|
The QFT-G and the T-SPOT.TB tests were more sensitive than the TST for diagnosis of latent tuberculosis infection in patients on hemodialysis while offering a comparable level of specificity . | {
"id": "C0019004",
"pos": [
129,
141
],
"name": "hemodialysis"
} | {
"id": "C0009450",
"pos": [
104,
113
],
"name": "infection"
} | 0NA
|
When Ile66 was substituted with alanine , glycine , cysteine , leucine , phenylalanine , tryptophan , tyrosine or valine , all the mutants dramatically increased the K ( m ) for D : -tagatose but slightly decreased the K ( m ) for D : -fructose , indicating that Ile66 is involved in substrate recognition . | {
"id": "C0010654",
"pos": [
52,
60
],
"name": "cysteine"
} | {
"id": "C0041485",
"pos": [
102,
110
],
"name": "tyrosine"
} | 0NA
|
We provide an analysis of retinal tissue deformation after fixation in Margo 's solution and paraffin embedding . | {
"id": "C0185023",
"pos": [
59,
67
],
"name": "fixation"
} | {
"id": "C0030415",
"pos": [
93,
101
],
"name": "paraffin"
} | 0NA
|
These results suggest that ARE may inhibit development of hyperalgesia via NMDA receptors based on activation of GABA(A ) receptors in the spinal cord . | {
"id": "C0037925",
"pos": [
139,
150
],
"name": "spinal cord"
} | {
"id": "C0020429",
"pos": [
58,
70
],
"name": "hyperalgesia"
} | 0NA
|
This is possible thanks to medical imagery and arteriography which helps in preventing operative accidents and in preserving the kidney . | {
"id": "C0022646",
"pos": [
129,
135
],
"name": "kidney"
} | {
"id": "C0003844",
"pos": [
47,
60
],
"name": "arteriography"
} | 0NA
|
The output is a table with all tumor-specific peptides derived from nucleotide substitutions , insertions , and deletions , along with comprehensive annotation , including HLA binding and similarity to normal peptides . | {
"id": "C0441587",
"pos": [
95,
105
],
"name": "insertions"
} | {
"id": "C0030956",
"pos": [
209,
217
],
"name": "peptides"
} | 0NA
|
Arterial hypertension is the most important modifiable risk factor for stroke . | {
"id": "C0020538",
"pos": [
0,
21
],
"name": "Arterial hypertension"
} | {
"id": "C0038454",
"pos": [
71,
77
],
"name": "stroke"
} | 0NA
|
To simultaneously image bone and synovium in the individual joints characteristically involved in early rheumatoid arthritis ( RA ) . | {
"id": "C0022417",
"pos": [
60,
66
],
"name": "joints"
} | {
"id": "C0003873",
"pos": [
104,
124
],
"name": "rheumatoid arthritis"
} | 11finding_site_of
|
The generally accepted theory states that the shoulder joint is actively internally rotated against the opponent while the elbow is fixed in flexion resulting in enormous violent torque forces across the humeral shaft . | {
"id": "C0013769",
"pos": [
123,
128
],
"name": "elbow"
} | {
"id": "C0588210",
"pos": [
204,
217
],
"name": "humeral shaft"
} | 0NA
|
Recently , we demonstrated correction of the tyrosinase gene using the same RDO in vivo , as detected by dark pigmentation of several hairs and DOPA staining of hair follicles in the treated skin of albino mice . | {
"id": "C0018494",
"pos": [
134,
139
],
"name": "hairs"
} | {
"id": "C0221971",
"pos": [
161,
175
],
"name": "hair follicles"
} | 0NA
|
In most cases , the affected tooth had a history of one or more episodes of pericoronitis . | {
"id": "C0040426",
"pos": [
29,
34
],
"name": "tooth"
} | {
"id": "C0031055",
"pos": [
76,
89
],
"name": "pericoronitis"
} | 0NA
|
Labetalol is readily absorbed in man after oral administration , but the drug , which is lipid soluble , undergoes considerable hepatic first-pass metabolism and has an absolute bioavailability of approximately 25 % . | {
"id": "C0013227",
"pos": [
73,
77
],
"name": "drug"
} | {
"id": "C0001563",
"pos": [
43,
62
],
"name": "oral administration"
} | 10direct_substance_of
|
In order to produce sufficient quantities of fibroblast growth factor-saporin ( rFGF-2-SAP ) mitotoxin for preclinical evaluation in models of diseases such as cancer and restenosis , we have undertaken the large-scale expression , purification , and characterization of the recombinant molecule . | {
"id": "C0006826",
"pos": [
160,
166
],
"name": "cancer"
} | {
"id": "C0012634",
"pos": [
143,
151
],
"name": "diseases"
} | 0NA
|
Excision of scar tissue was done , followed by end-to-end anastomosis in 32 ( 64 % ) , penile pedicle flap in 16 ( 32 % ) , and buccal mucosal graft in 2 ( 4 % ) of the patients . | {
"id": "C0015252",
"pos": [
0,
8
],
"name": "Excision"
} | {
"id": "C0241158",
"pos": [
12,
23
],
"name": "scar tissue"
} | 0NA
|
AEs ( including ADRs ) were registered in 8.8 % of the participants ; most frequent AEs/ADRs were postmenopausal hemorrhage ( 2.9 % ) and drug ineffective ( 1.4 % ) . | {
"id": "C0013227",
"pos": [
138,
142
],
"name": "drug"
} | {
"id": "C0032776",
"pos": [
98,
123
],
"name": "postmenopausal hemorrhage"
} | 0NA
|
The ptosis was treated at 3 weeks with bilateral eyelid suspension surgery , and surgical repair of the exotropia was done at 4 months . | {
"id": "C0374711",
"pos": [
81,
96
],
"name": "surgical repair"
} | {
"id": "C0005745",
"pos": [
4,
10
],
"name": "ptosis"
} | 0NA
|