Document ID: 32024R0197
Language: ENG

<table><col/><col/><col/><tbody><tr><td><img/></td><td><p>Official Journal<br/>of the European Union</p></td><td><p>EN</p><p>Series L</p></td></tr></tbody></table>
<table><col/><col/><col/><tbody><tr><td/><td><p>2024/197</p></td><td><p>5.1.2024</p></td></tr></tbody></table>
COMMISSION DELEGATED REGULATION (EU) 2024/197
of 19 October 2023
amending Regulation (EC) No 1272/2008 as regards the harmonised classification and labelling of certain substances
(Text with EEA relevance)
THE EUROPEAN COMMISSION,
Having regard to the Treaty on the Functioning of the European Union,
Having regard to Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 ( 1 ) , and in particular Article 37(5) thereof,
Whereas:
<table><col/><col/><tbody><tr><td><p>(1)</p></td><td><p>Table 3 of Part 3 of Annex&#160;VI to Regulation (EC) No&#160;1272/2008 contains the list of harmonised classification and labelling of hazardous substances based on the criteria set out in Parts 2 to 5 of Annex&#160;I to that Regulation.</p></td></tr></tbody></table>
<table><col/><col/><tbody><tr><td><p>(2)</p></td><td><p>Proposals to introduce harmonised classification and labelling of certain substances and to update the harmonised classification and labelling of certain other substances have been submitted to the European Chemicals Agency (the &#8216;Agency&#8217;) pursuant to Article&#160;37 of Regulation (EC) No&#160;1272/2008. The Committee for Risk Assessment of the Agency (RAC) adopted, after having taken account of the comments received from the parties concerned, the following opinions&#160;<a>(<span>2</span>)</a> on those proposals:</p><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning benzyl(diethylamino)diphenylphosphonium 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenolate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning benzyltriphenylphosphonium, salt with 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis[phenol] (1:1);</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning reaction mass of 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol and benzyl(diethylamino)diphenylphosphonium 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenolate&#160;(1:1);</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning reaction mass of 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol and benzyltriphenylphosphonium, salt with 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol&#160;(1:1);</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol; bisphenol AF;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning cinnamaldehyde; 3-phenylprop-2-enal; cinnamic aldehyde; cinnamal [1], (2E)-3-phenylprop-2-enal [2];</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning benfluralin (ISO);<span>N</span>-butyl-<span>N</span>-ethyl-&#945;,&#945;,&#945;-trifluoro-2,6-dinitro-<span>p</span>-toluidine;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion 18&#160;March 2021 concerning 3,3'-dimethylbiphenyl-4,4'-diyl diisocyanate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning foramsulfuron (ISO); 2-{[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-4-formamido-<span>N,N</span>-dimethylbenzamide; 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-dimethylcarbamoyl-5-formamidophenylsulfonyl)urea;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning ethyl acrylate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning methyl acrylate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>methyl propenoate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning methyl methacrylate; methyl 2-methylprop-2-enoate; methyl 2-methylpropenoate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning transfluthrin (ISO); 2,3,5,6-tetrafluorobenzyl (1<span>R</span>,3<span>S</span>)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning allyl methacrylate; 2-methyl-2-propenoic acid 2-propenyl ester;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 18&#160;March 2021 concerning mepiquat chloride (ISO); 1,1-dimethylpiperidinium chloride;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 10&#160;June 2021 concerning triethylamine;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 10&#160;June 2021 concerning di-<span>n</span>-butylamine;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 10&#160;June 2021 concerning 4-nitrosomorpholine;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 10&#160;June 2021 concerning difenoconazole (ISO); 1-({2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole; 3-chloro-4-[(2RS,4RS;2RS,4SR)-4-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl]phenyl 4-chlorophenyl ether;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion 10&#160;June 2021 concerning<span>N,N</span>-dimethyl-p-toluidine;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 10&#160;June 2021 concerning potassium chlorate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 10&#160;June 2021 concerning sodium chlorate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 10&#160;June 2021 Concerning reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and&#160;1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 10&#160;June 2021 concerning metribuzin (ISO); 4-amino-6-tert-butyl-3-methylthio-1,2,4-triazin-5(4<span>H</span>)-one; 4-amino-4,5-dihydro-6-(1,1-dimethylethyl)-3-methylthio-1,2,4-triazin-5-one;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion 16&#160;September 2021 concerning lithium carbonate [1] lithium chloride [2] lithium hydroxide [3];</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning dimethyl propylphosphonate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning dibutyltin maleate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning dibutyltin oxide;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning clothianidin (ISO); (<span>E)</span>-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning cymoxanil (ISO); 2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning nonylphenol, branched and linear, ethoxylated (with average molecular weight &lt;&#160;352&#160;g/mol) [includes ortho-, meta-, para- isomers or any combination thereof];</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning nonylphenol, branched and linear, ethoxylated (with 352&#160;g/mol &#8804; average molecular weight &lt;&#160;704&#160;g/mol) [includes ortho-, meta-, para- isomers or any combination thereof];</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning nonylphenol, branched and linear, ethoxylated (with 704&#160;g/mol &#8804; average molecular weight &#8804;&#160;1&#160;540 g/mol) [includes ortho-, meta-, para- isomers or any combination thereof];</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning 1-phenylethan-1-one (1-phenylethylidene)hydrazone;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning 9-[2-(ethoxycarbonyl)phenyl]-3,6-bis(ethylamino)-2,7-dimethylxanthylium chloride; Basic Red 1;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning picolinafen (ISO);<span>N</span>-(4-fluorophenyl)-6-[3-(trifluoromethyl)phenoxy]pyridine-2-carboxamide; 4&#8242;-fluoro-6-[(&#945;,&#945;,&#945;-trifluoro-m-tolyl)oxy]picolinanilide;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning diuron (ISO); 3-(3,4-dichlorophenyl)-1,1-dimethylurea;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning hydrogen sulphide, hydrogen sulfide;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning benzyl alcohol;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning resorcinol; 1,3-benzenediol;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning 2,2',6,6'-tetrabromo-4,4'-isopropylidenediphenol; tetrabromobisphenol-A;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 16&#160;September 2021 concerning a reassessment at the request of the Commission to review the harmonised classification of lead (environment);</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning 2,2'-[[3-methyl-4-[(4-nitrophenyl)azo]phenyl]imino]bisethanol;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning 1,4-Benzenediamine,<span>N,N&#8217;</span>-mixed Ph and tolyl derivs.; Reaction mass of<span>N</span>-phenyl,<span>N&#8217;</span>-o-tolyl-phenylene diamine,<span>N,N&#8217;</span>-diphenyl-p-phenylene diamine and<span>N,N&#8217;</span>-di-o-tolyl-phenylene diamine;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning tetramethylene dimethacrylate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning 7,7,9(or 7,9,9)-trimethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diyl bismethacrylate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning 2,2'-ethylenedioxydiethyl dimethacrylate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning bifenox (ISO); methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning 4-methylimidazole;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning sulfur dioxide;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning 1,2-benzisothiazol-3(2<span>H</span>)-one; 1,2-benzisothiazolin-3-one;</p></td></tr></tbody></table><table><col/><col/><tbody><tr><td><p>&#8212;</p></td><td><p>Opinion of 26&#160;November 2021 concerning benalaxyl (ISO); methyl<span>N</span>-(2,6-dimethylphenyl)-<span>N</span>-(phenylacetyl)-DL-alaninate.</p></td></tr></tbody></table></td></tr></tbody></table>
<table><col/><col/><tbody><tr><td><p>(3)</p></td><td><p>The Commission has received additional information from stakeholders contesting the scientific assessment set out in the RAC opinion of 26&#160;November 2021 concerning 1,4-Benzenediamine, N,N&#8217;-mixed Ph and tolyl derivs. and in the RAC opinion of 16&#160;September 2021 concerning dibutyltin oxide. The additional information has been assessed and has not been found sufficient to cast doubts on the scientific analysis contained in the RAC opinions. It is therefore appropriate to introduce the harmonised classification and labelling of the substances concerned on the basis of the assessment made in those opinions.</p></td></tr></tbody></table>
<table><col/><col/><tbody><tr><td><p>(4)</p></td><td><p>The RAC opinion of 16&#160;September 2021 concerning the environmental toxicity of lead put forward various possible options to update the harmonised classification of lead for aquatic toxicity. These options give the possibility to either have a single entry for both lead in powder form (&#8216;lead powder&#8217;) and in massive form (&#8216;lead massive&#8217;) or to keep two separate entries, one for each form. However, as data for lead massive indicates a lower dissolution in water than for lead powder, a calculation in accordance with Part 4 of Annex&#160;I to Regulation (EC) No&#160;1272/2008 leads to a less severe classification for lead massive. It is therefore appropriate to amend the existing aquatic toxicity classification for lead powder with regard to the M-factor and to introduce a different aquatic toxicity classification for lead massive.</p></td></tr></tbody></table>
<table><col/><col/><tbody><tr><td><p>(5)</p></td><td><p>In light of the RAC opinions, it is therefore appropriate to introduce or update the harmonised classification and labelling of the substances concerned on the basis of the assessment made in those opinions and following the further assessments.</p></td></tr></tbody></table>
<table><col/><col/><tbody><tr><td><p>(6)</p></td><td><p>Regulation (EC) No&#160;1272/2008 should therefore be amended accordingly.</p></td></tr></tbody></table>
<table><col/><col/><tbody><tr><td><p>(7)</p></td><td><p>As regards the classification of methyl methacrylate as a respiratory sensitiser and the classification of lithium carbonate, lithium chloride and lithium hydroxide as reproductive toxic substances the Commission has received additional information from stakeholders after obtaining the RAC opinions of 18&#160;March 2021 and of 16&#160;September 2021 respectively concerning those substances. Since that new scientific information requires further assessment by RAC, methyl methacrylate, lithium carbonate, lithium chloride and lithium hydroxide recommended in the RAC opinions should not be subject to harmonised classification and labelling at this stage.</p></td></tr></tbody></table>
<table><col/><col/><tbody><tr><td><p>(8)</p></td><td><p>Compliance with the new or updated harmonised classifications should not be required immediately as a certain period of time is necessary to allow suppliers to adapt the labelling and packaging of substances and mixtures to the new or updated classifications and to sell existing stocks subject to the pre-existing regulatory requirements. That period of time is also necessary to allow suppliers sufficient time to take the actions required to ensure continuing compliance with other legal requirements following the changes made under this Regulation. Suppliers should, however, have the possibility to apply the new or updated harmonised classifications, and to adapt the labelling and packaging accordingly, on a voluntary basis before the date of application of this Regulation, to ensure a high level of protection of human health and of the environment and to provide sufficient flexibility to suppliers,</p></td></tr></tbody></table>
HAS ADOPTED THIS REGULATION:
Article 1
Annex VI to Regulation (EC) No 1272/2008 is amended as set out in the Annex to this Regulation.
Article 2
This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union .
It shall apply from 1 September 2025.
However, suppliers may already before that date classify, label and package substances and mixtures in accordance with Regulation (EC) No 1272/2008 as amended by this Regulation.
This Regulation shall be binding in its entirety and directly applicable in all Member States.
Done at Brussels, 19 October 2023.
For the Commission
The President
Ursula VON DER LEYEN
( 1 ) OJ L 353, 31.12.2008, p. 1 .
( 2 ) The opinions are accessible via the following website: https://echa.europa.eu/registry-of-clh-intentions-until-outcome/-/dislist/name/-/ecNumber/-/casNumber/-/dte_receiptFrom/-/dte_receiptTo/-/prc_public_status/Opinion+Adopted/dte_withdrawnFrom/-/dte_withdrawnTo/-/sbm_expected_submissionFrom/-/sbm_expected_submissionTo/-/dte_finalise_deadlineFrom/-/dte_finalise_deadlineTo/-/haz_addional_hazard/-/lec_submitter/-/dte_assessmentFrom/-/dte_assessmentTo/-/prc_regulatory_programme/-/.The opinion of 16 September 2021 concerning a reassessment at the request of the Commission is accessible via the following website: https://echa.europa.eu/about-us/who-we-are/committee-for-risk-assessment/opinions-of-the-rac-adopted-under-specific-echa-s-executive-director-requests.
ANNEX
In Annex VI to Regulation (EC) No 1272/2008, Table 3 of Part 3 is amended as follows:
<table><col/><col/><tbody><tr><td><p>(1)</p></td><td><p>the following entries are inserted following the order of the index numbers corresponding to each entry:</p><table><col/><col/><col/><col/><col/><col/><col/><col/><col/><col/><col/><tbody><tr><td><p>Index No</p></td><td><p>Chemical Name</p></td><td><p>EC No</p></td><td><p>CAS No</p></td><td><p>Classification</p></td><td><p>Labelling</p></td><td><p>Specific Conc. Limits, M- factors and ATE</p></td><td><p>Notes</p></td></tr><tr><td><p>Hazard Class and Category Code(s)</p></td><td><p>Hazard statement Code(s)</p></td><td><p>Pictogram, Signal Word Code(s)</p></td><td><p>Hazard statement Code(s)</p></td><td><p>Suppl. Hazard statement Code(s)</p></td></tr><tr><td><p>&#8216;015-204-00-5</p></td><td><p>benzyl(diethylamino)diphenylphosphonium 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenolate</p></td><td><p>479-100-5</p></td><td><p>577705-90-9</p></td><td><p>Repr. 1B</p></td><td><p>H360F</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H360F&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;015-205-00-0</p></td><td><p>benzyltriphenylphosphonium, salt with 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis[phenol] (1:1)</p></td><td><p>278-305-5</p></td><td><p>75768-65-9</p></td><td><p>Repr. 1B</p></td><td><p>H360F</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H360F&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;015-206-00-6</p></td><td><p>reaction mass of 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol and benzyl(diethylamino)diphenylphosphonium 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenolate (1:1)</p></td><td><p>&#8212;</p></td><td><p>&#8212;</p></td><td><p>Repr. 1B</p></td><td><p>H360F</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H360F&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;015-207-00-1</p></td><td><p>reaction mass of 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol and benzyltriphenylphosphonium, salt with 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol (1:1)</p></td><td><p>&#8212;</p></td><td><p>&#8212;</p></td><td><p>Repr. 1B</p></td><td><p>H360F</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H360F&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;015-208-00-7</p></td><td><p>dimethyl propylphosphonate</p></td><td><p>242-555-3</p></td><td><p>18755-43-6</p></td><td><p>Muta. 1B</p><p>Repr. 1B</p></td><td><p>H340</p><p>H360Df</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H340</p><p>H360Df&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;050-034-00-5</p></td><td><p>dibutyltin maleate</p></td><td><p>201-077-5</p></td><td><p>78-04-6</p></td><td><p>Muta. 2</p><p>Repr. 1B</p><p>Acute Tox. 2</p><p>Acute Tox. 4</p><p>STOT RE 1</p><p>Skin Corr. 1</p><p>Eye Dam. 1</p></td><td><p>H341</p><p>H360FD</p><p>H330</p><p>H302</p><p>H372 (immune system)</p><p>H314</p><p>H318</p></td><td><p>GHS08</p><p>GHS06</p><p>GHS05</p><p>Dgr</p></td><td><p>H341</p><p>H360FD</p><p>H330</p><p>H302</p><p>H372 (immune system)</p><p>H314</p></td><td><p>&#160;</p></td><td><p>inhalation:</p><p>ATE&#160;= 0,317&#160;mg/L (dusts or mists)</p><p>oral:</p><p>ATE&#160;= 510 mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;050-035-00-0</p></td><td><p>dibutyltin oxide</p></td><td><p>212-449-1</p></td><td><p>818-08-6</p></td><td><p>Muta. 2</p><p>Repr. 1B</p><p>Acute Tox. 3</p><p>STOT RE 1</p><p>Skin Irrit. 2</p><p>Eye Dam. 1</p></td><td><p>H341</p><p>H360FD</p><p>H301</p><p>H372 (immune system)</p><p>H315</p><p>H318</p></td><td><p>GHS08</p><p>GHS06</p><p>GHS05</p><p>Dgr</p></td><td><p>H341</p><p>H360FD</p><p>H301</p><p>H372 (immune system)</p><p>H315</p><p>H318</p></td><td><p>&#160;</p></td><td><p>oral:</p><p>ATE&#160;= 170 mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;603-244-00-1</p></td><td><p>reaction mass of 1-(2,3-epoxypropoxy)&#8211;2,2-bis ((2,3-epoxypropoxy)methyl) butane and&#160;1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane</p></td><td><p>&#8212;</p></td><td><p>&#8212;</p></td><td><p>Muta. 2</p><p>Repr. 1B</p></td><td><p>H341</p><p>H360F</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H341</p><p>H360F&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;603-245-00-7</p></td><td><p>2,2'-[[3-methyl-4-[(4-nitrophenyl)azo]phenyl]imino]bisethanol</p></td><td><p>221-665-5</p></td><td><p>3179-89-3</p></td><td><p>Skin Sens. 1</p></td><td><p>H317</p></td><td><p>GHS07</p><p>Wng</p></td><td><p>H317&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;603-246-00-2</p></td><td><p>3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol</p></td><td><p>211-477-1</p></td><td><p>647-42-7</p></td><td><p>STOT RE 2</p><p>Aquatic Chronic 1</p></td><td><p>H373 (teeth, bones)</p><p>H410</p></td><td><p>GHS08</p><p>GHS09</p><p>Wng</p></td><td><p>H373 (teeth, bones)</p><p>H410</p></td><td><p>&#160;</p></td><td><p>M&#160;= 1&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;604-099-00-7</p></td><td><p>4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol; bisphenol AF</p></td><td><p>216-036-7</p></td><td><p>1478-61-1</p></td><td><p>Repr. 1B</p></td><td><p>H360F</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H360F&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;604-100-00-0</p></td><td><p>nonylphenol, branched and linear, ethoxylated (with average molecular weight &#8804;&#160;1&#160;540  g/mol) [includes ortho-, meta-, para- isomers or any combination thereof]</p></td><td><p>500-315-8</p><p>500-024-6</p><p>500-045-0</p><p>500-209-1</p><p>248-762-5</p><p>243-816-4</p><p>248-291-5</p><p>&#8212;</p><p>230-770-5&#160;248-743-1&#160;247-555-7&#160;248-293-6</p><p>&#8212;</p><p>and others</p></td><td><p>127087-87-0</p><p>9016-45-9</p><p>26027-38-3</p><p>68412-54-4</p><p>27986-36-3</p><p>20427-84-3</p><p>27176-93-8</p><p>1119449-38-5&#160;7311-27-5&#160;27942-27-4&#160;26264-02-8&#160;27177-05-5&#160;14409-72-4 and others</p></td><td><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H400</p><p>H410</p></td><td><p>GHS09</p><p>Wng</p></td><td><p>H410</p></td><td><p>&#160;</p></td><td><p>M&#160;= 1</p><p>M&#160;= 10&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;606-155-00-6</p></td><td><p>cinnamaldehyde; 3-phenylprop-2-enal;</p><p>cinnamic aldehyde; cinnamal; [1]</p><p>(2<span>E</span>)-3-phenylprop-2-enal [2]</p></td><td><p>203-213-9 [1] - [2]</p></td><td><p>104-55-2 [1] 14371-10-9 [2]</p></td><td><p>Skin Sens. 1A</p></td><td><p>H317</p></td><td><p>GHS07</p><p>Wng</p></td><td><p>H317</p></td><td><p>&#160;</p></td><td><p>Skin Sens. 1; H317: C &#8805;&#160;0,01&#160;%&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;607-766-00-0</p></td><td><p>tetramethylene dimethacrylate</p></td><td><p>218-218-1</p></td><td><p>2082-81-7</p></td><td><p>Skin Sens. 1B</p></td><td><p>H317</p></td><td><p>GHS07</p><p>Wng</p></td><td><p>H317&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;607-767-00-6</p></td><td><p>7,7,9(or 7,9,9)-trimethyl&#8211;4,13-dioxo&#8211;3,14-dioxa&#8211;5,12-diazahexadecane&#8211;1,16-diyl bismethacrylate</p></td><td><p>276-957-5</p></td><td><p>72869-86-4</p></td><td><p>Skin Sens. 1B</p></td><td><p>H317</p></td><td><p>GHS07</p><p>Wng</p></td><td><p>H317&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;607-768-00-1</p></td><td><p>2,2'-ethylenedioxydiethyl dimethacrylate</p></td><td><p>203-652-6</p></td><td><p>109-16-0</p></td><td><p>Skin Sens. 1B</p></td><td><p>H317</p></td><td><p>GHS07</p><p>Wng</p></td><td><p>H317&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;607-769-00-7</p></td><td><p>bifenox (ISO); methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate</p></td><td><p>255-894-7</p></td><td><p>42576-02-3</p></td><td><p>Acute Tox. 4</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H302</p><p>H400</p><p>H410</p></td><td><p>GHS07</p><p>GHS09</p><p>Wng</p></td><td><p>H302</p><p>H410</p></td><td><p>&#160;</p></td><td><p>oral:</p><p>ATE&#160;= 1&#160;500  mg/kg bw</p><p>M&#160;= 1&#160;000</p><p>M&#160;= 1&#160;000 &#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;612-295-00-9</p></td><td><p>benfluralin (ISO);<span>N</span>-butyl-<span>N</span>-ethyl-&#945;,&#945;,&#945;-trifluoro-2,6-dinitro-<span>p</span>-toluidine</p></td><td><p>217-465-2</p></td><td><p>1861-40-1</p></td><td><p>Carc. 2</p><p>Repr. 2</p><p>Skin Irrit. 2</p><p>Eye Irrit. 2</p><p>Skin Sens. 1</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H351</p><p>H361d</p><p>H315</p><p>H319</p><p>H317</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS07</p><p>GHS09</p><p>Wng</p></td><td><p>H351</p><p>H361d</p><p>H315</p><p>H319</p><p>H317</p><p>H410</p></td><td><p>&#160;</p></td><td><p>M&#160;= 10</p><p>M&#160;= 10&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;612-296-00-4</p></td><td><p><span>N,N</span>-dimethyl-<span>p</span>-toluidine</p></td><td><p>202-805-4</p></td><td><p>99-97-8</p></td><td><p>Carc. 1B</p><p>Acute Tox. 4</p><p>Acute Tox. 3</p><p>STOT RE 2</p><p>Aquatic Chronic 3</p></td><td><p>H350</p><p>H332</p><p>H301</p><p>H373 (blood system, respiratory tract)</p><p>H412</p></td><td><p>GHS08</p><p>GHS06</p><p>Dgr</p></td><td><p>H350</p><p>H332</p><p>H301</p><p>H373 (blood system, respiratory tract)</p><p>H412</p></td><td><p>&#160;</p></td><td><p>inhalation:</p><p>ATE&#160;= 1,4&#160;mg/L (dusts or mists)</p><p>oral:</p><p>ATE&#160;= 140 mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;612-297-00-X</p></td><td><p>1-phenylethan-1-one (1-phenylethylidene)hydrazone</p></td><td><p>211-979-0</p></td><td><p>729-43-1</p></td><td><p>Skin Sens. 1</p></td><td><p>H317</p></td><td><p>GHS07</p><p>Wng</p></td><td><p>H317&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;612-298-00-5</p></td><td><p>1,4-Benzenediamine,<span>N,N&#8217;</span>-mixed Ph and tolyl derivs.;</p></td><td><p>273-227-8</p></td><td><p>68953-84-4</p></td><td><p>Repr. 1B</p><p>Skin Sens. 1</p></td><td><p>H360FD</p><p>H317</p></td><td><p>GHS08</p><p>GHS07</p><p>Dgr</p></td><td><p>H360FD</p><p>H317&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;613-346-00-8</p></td><td><p>4-nitrosomorpholine</p></td><td><p>&#8212;</p></td><td><p>59-89-2</p></td><td><p>Carc. 1B</p><p>Muta. 2</p><p>STOT RE 1</p></td><td><p>H350</p><p>H341</p><p>H372 (liver)</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H350</p><p>H341</p><p>H372 (liver)</p></td><td><p>&#160;</p></td><td><p>Carc. 1B; H350: C &#8805;&#160;0,001&#160;%&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;613-347-00-3</p></td><td><p>difenoconazole (ISO); 1-({2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl&#8211;1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole; 3-chloro-4-[(2<span>RS</span>,4<span>RS</span>;2<span>RS</span>,4<span>SR</span>)-4-methyl-2-(1<span>H</span>-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl]phenyl 4-chlorophenyl ether</p></td><td><p>&#8212;</p></td><td><p>119446-68-3</p></td><td><p>Carc. 2</p><p>Acute Tox. 4</p><p>Eye Irrit. 2</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H351</p><p>H302</p><p>H319</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS07</p><p>GHS09</p><p>Wng</p></td><td><p>H351</p><p>H302</p><p>H319</p><p>H410</p></td><td><p>&#160;</p></td><td><p>oral:</p><p>ATE&#160;= 1&#160;450  mg/kg bw</p><p>M&#160;= 10</p><p>M&#160;= 10&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;613-348-00-9</p></td><td><p>9-[2-(ethoxycarbonyl)phenyl]&#8211;3,6-bis(ethylamino)&#8211;2,7-dimethylxanthylium chloride; Basic Red 1</p></td><td><p>213-584-9</p></td><td><p>989-38-8</p></td><td><p>Acute Tox. 3</p><p>Eye Dam. 1</p><p>Skin Sens. 1</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H301</p><p>H318</p><p>H317</p><p>H400</p><p>H410</p></td><td><p>GHS06</p><p>GHS05</p><p>GHS09</p><p>Dgr</p></td><td><p>H301</p><p>H318</p><p>H317</p><p>H410</p></td><td><p>&#160;</p></td><td><p>oral:</p><p>ATE&#160;= 280 mg/kg bw</p><p>M&#160;= 10</p><p>M&#160;= 1&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;613-349-00-4</p></td><td><p>4-methylimidazole</p></td><td><p>212-497-3</p></td><td><p>822-36-6</p></td><td><p>Carc. 1B</p><p>Repr. 1B</p></td><td><p>H350</p><p>H360Fd</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H350</p><p>H360Fd&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;615-051-00-X</p></td><td><p>3,3'-dimethylbiphenyl&#8211;4,4'-diyl diisocyanate</p></td><td><p>202-112-7</p></td><td><p>91-97-4</p></td><td><p>Carc. 2</p><p>Resp. Sens. 1</p><p>Skin Sens. 1A</p></td><td><p>H351</p><p>H334</p><p>H317</p></td><td><p>GHS08</p><p>Dgr</p></td><td><p>H351</p><p>H334</p><p>H317</p></td><td><p>&#160;</p></td><td><p>Skin Sens. 1A; H317: C &#8805;&#160;0,001&#160;%&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;616-241-00-5</p></td><td><p>foramsulfuron (ISO); 2-{[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-4-formamido-<span>N,N</span>-dimethylbenzamide; 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-dimethylcarbamoyl-5-formamidophenylsulfonyl)urea</p></td><td><p>&#8212;</p></td><td><p>173159-57-4</p></td><td><p>Carc. 2</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H351</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS09</p><p>Wng</p></td><td><p>H351</p><p>H410</p></td><td><p>&#160;</p></td><td><p>M&#160;= 1&#160;000</p><p>M&#160;= 100&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;616-242-00-0</p></td><td><p>picolinafen (ISO);<span>N</span>-(4-fluorophenyl)-6-[3-(trifluoromethyl)phenoxy]pyridine-2-carboxamide; 4&#8242;-fluoro-6-[(&#945;,&#945;,&#945;-trifluoro-<span>m</span>-tolyl)oxy]picolinanilide</p></td><td><p>&#8212;</p></td><td><p>137641-05-5</p></td><td><p>STOT RE 2</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H373 (blood system, thyroid)</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS09</p><p>Wng</p></td><td><p>H373 (blood system, thyroid)</p><p>H410</p></td><td><p>&#160;</p></td><td><p>M&#160;= 1&#160;000</p><p>M&#160;= 1&#160;000 &#8217;</p></td><td><p>&#160;</p></td></tr></tbody></table></td></tr></tbody></table>
<table><col/><col/><tbody><tr><td><p>(2)</p></td><td><p>the entries corresponding to index numbers 006-015-00-9; 015-203-00-X; 016-001-00-4; 016-011-00-9; 017-004-00-3; 017-005-00-9; 082-013-00-1; 082-014-00-7; 603-057-00-5; 604-010-00-1; 604-074-00-0; 606-034-00-8; 607-032-00-X; 607-034-00-0; 607-223-00-8; 607-246-00-3; 612-004-00-5; 612-049-00-0; 612-056-00-9; 613-088-00-6; 613-127-00-7; 613-307-00-5; 616-035-00-5; 616-104-00-X are replaced by the following entries respectively:</p><table><col/><col/><col/><col/><col/><col/><col/><col/><col/><col/><col/><tbody><tr><td><p>Index No</p></td><td><p>Chemical Name</p></td><td><p>EC No</p></td><td><p>CAS No</p></td><td><p>Classification</p></td><td><p>Labelling</p></td><td><p>Specific Conc. Limits, M-factors and ATE</p></td><td><p>Notes</p></td></tr><tr><td><p>Hazard Class and Category Code(s)</p></td><td><p>Hazard statement Code(s)</p></td><td><p>Pictogram, Signal Word Code(s)</p></td><td><p>Hazard statement Code(s)</p></td><td><p>Suppl. Hazard statement Code(s)</p></td></tr><tr><td><p>&#8216;006-015-00-9</p></td><td><p>diuron (ISO); 3-(3,4-dichlorophenyl)&#8211;1,1-dimethylurea</p></td><td><p>206-354-4</p></td><td><p>330-54-1</p></td><td><p>Carc. 1B</p><p>STOT RE 2</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H350</p><p>H373 (blood system)</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS09</p><p>Dgr</p></td><td><p>H350</p><p>H373 (blood system)</p><p>H410</p></td><td><p>&#160;</p></td><td><p>M&#160;= 100</p><p>M&#160;= 100&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;015-203-00-X</p></td><td><p>diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide</p></td><td><p>278-355-8</p></td><td><p>75980-60-8</p></td><td><p>Repr. 1B</p><p>Skin Sens. 1B</p></td><td><p>H360Fd</p><p>H317</p></td><td><p>GHS08</p><p>GHS07</p><p>Dgr</p></td><td><p>H360Fd</p><p>H317&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;016-001-00-4</p></td><td><p>hydrogen sulphide, hydrogen sulfide</p></td><td><p>231-977-3</p></td><td><p>7783-06-4</p></td><td><p>Flam. Gas 1A</p><p>Press. Gas</p><p>Acute Tox. 2</p><p>Aquatic Acute 1</p></td><td><p>H220</p><p>H330</p><p>H400</p></td><td><p>GHS02</p><p>GHS06</p><p>GHS09</p><p>Dgr</p></td><td><p>H220</p><p>H330</p><p>H400</p></td><td><p>&#160;</p></td><td><p>inhalation: ATE&#160;= 440 ppmV (gases)</p></td><td><p>U&#8217;</p></td></tr><tr><td><p>&#8216;016-011-00-9</p></td><td><p>sulphur dioxide; sulfur dioxide</p></td><td><p>231-195-2</p></td><td><p>7446-09-5</p></td><td><p>Press. Gas</p><p>Acute Tox. 3</p><p>STOT SE 1</p><p>Skin. Corr. 1B</p></td><td><p>H331</p><p>H370 (respiratory system) (inhalation)</p><p>H314</p></td><td><p>GHS04</p><p>GHS06</p><p>GHS08</p><p>GHS05</p><p>Dgr</p></td><td><p>H331</p><p>H370 (respiratory system) (inhalation)</p><p>H314</p></td><td><p>&#160;</p></td><td><p>inhalation: ATE&#160;= 1&#160;000  ppmV (gases)</p></td><td><p>U, 5&#8217;</p></td></tr><tr><td><p>&#8216;017-004-00-3</p></td><td><p>potassium chlorate</p></td><td><p>223-289-7</p></td><td><p>3811-04-9</p></td><td><p>Ox. Sol. 1</p><p>Acute Tox. 3</p></td><td><p>H271</p><p>H301</p></td><td><p>GHS03</p><p>GHS06</p><p>Dgr</p></td><td><p>H271</p><p>H301</p></td><td><p>&#160;</p></td><td><p>oral: ATE&#160;= 100 mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;017-005-00-9</p></td><td><p>sodium chlorate</p></td><td><p>231-887-4</p></td><td><p>7775-09-9</p></td><td><p>Ox. Sol. 1</p><p>Acute Tox. 3</p></td><td><p>H271</p><p>H301</p></td><td><p>GHS03</p><p>GHS06</p><p>Dgr</p></td><td><p>H271</p><p>H301</p></td><td><p>&#160;</p></td><td><p>oral: ATE&#160;= 100 mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;082-013-00-1</p></td><td><p>lead powder;</p><p>[particle diameter &lt;&#160;1 mm]</p></td><td><p>231-100-4</p></td><td><p>7439-92-1</p></td><td><p>Repr. 1A</p><p>Lact.</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H360FD</p><p>H362</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS09</p><p>Dgr</p></td><td><p>H360FD</p><p>H362</p><p>H410</p></td><td><p>&#160;</p></td><td><p>Repr. 1A;</p><p>H360D: C &#8805;&#160;0,03&#160;%</p><p>M&#160;= 10</p><p>M&#160;= 100&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;082-014-00-7</p></td><td><p>lead massive:</p><p>[particle diameter &#8805;&#160;1 mm]</p></td><td><p>231-100-4</p></td><td><p>7439-92-1</p></td><td><p>Repr. 1A</p><p>Lact.</p><p>Aquatic Chronic 1</p></td><td><p>H360FD</p><p>H362</p><p>H410</p></td><td><p>GHS08</p><p>GHS09</p><p>Dgr</p></td><td><p>H360FD</p><p>H362</p><p>H410</p></td><td><p>&#160;</p></td><td><p>M&#160;= 10&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;603-057-00-5</p></td><td><p>benzyl alcohol</p></td><td><p>202-859-9</p></td><td><p>100-51-6</p></td><td><p>Acute Tox. 4</p><p>Eye Irrit. 2</p><p>Skin Sens. 1B</p></td><td><p>H302</p><p>H319</p><p>H317</p></td><td><p>GHS07</p><p>Wng</p></td><td><p>H302</p><p>H319</p><p>H317</p></td><td><p>&#160;</p></td><td><p>oral: ATE&#160;= 1&#160;200  mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;604-010-00-1</p></td><td><p>resorcinol; 1,3-benzenediol</p></td><td><p>203-585-2</p></td><td><p>108-46-3</p></td><td><p>Acute Tox. 4</p><p>STOT SE 1</p><p>Skin Irrit. 2</p><p>Eye Irrit. 2</p><p>Skin Sens. 1B</p><p>Aquatic Acute 1</p></td><td><p>H302</p><p>H370 (nervous system)</p><p>H315</p><p>H319</p><p>H317</p><p>H400</p></td><td><p>GHS07</p><p>GHS08</p><p>GHS09</p><p>Dgr</p></td><td><p>H302</p><p>H370 (nervous system)</p><p>H315</p><p>H319</p><p>H317</p><p>H400</p></td><td><p>&#160;</p></td><td><p>oral: ATE&#160;= 500 mg/kg bw</p><p>M&#160;= 1&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;604-074-00-0</p></td><td><p>2,2',6,6'-tetrabromo&#8211;4,4'-isopropylidenediphenol; tetrabromobisphenol-A</p></td><td><p>201-236-9</p></td><td><p>79-94-7</p></td><td><p>Carc. 1B</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H350</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS09</p><p>Dgr</p></td><td><p>H350</p><p>H410&#8217;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;606-034-00-8</p></td><td><p>metribuzin (ISO); 4-amino-6-tert-butyl-3-methylthio-1,2,4-triazin-5(4<span>H</span>)-one; 4-amino-4,5-dihydro-6-(1,1-dimethylethyl)-3-methylthio-1,2,4-triazin-5-one</p></td><td><p>244-209-7</p></td><td><p>21087-64-9</p></td><td><p>Acute Tox. 4</p><p>STOT RE 2</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H302</p><p>H373 (blood system)</p><p>H400</p><p>H410</p></td><td><p>GHS07</p><p>GHS08</p><p>GHS09</p><p>Wng</p></td><td><p>H302</p><p>H373 (blood system)</p><p>H410</p></td><td><p>&#160;</p></td><td><p>oral: ATE&#160;= 320 mg/kg bw</p><p>M&#160;= 10</p><p>M&#160;= 10&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;607-032-00-X</p></td><td><p>ethyl acrylate</p></td><td><p>205-438-8</p></td><td><p>140-88-5</p></td><td><p>Flam. Liq. 2</p><p>Acute Tox. 3</p><p>Acute Tox. 4</p><p>Acute Tox. 4</p><p>STOT SE 3</p><p>Skin Irrit. 2</p><p>Eye Irrit. 2</p><p>Skin Sens. 1</p></td><td><p>H225</p><p>H331</p><p>H312</p><p>H302</p><p>H335</p><p>H315</p><p>H319</p><p>H317</p></td><td><p>GHS02</p><p>GHS06</p><p>Dgr</p></td><td><p>H225</p><p>H331</p><p>H312</p><p>H302</p><p>H335</p><p>H315</p><p>H319</p><p>H317</p></td><td><p>&#160;</p></td><td><p>inhalation: ATE&#160;= 9 mg/L (vapours)</p><p>dermal: ATE&#160;= 1&#160;800  mg/kg bw</p><p>oral: ATE&#160;= 1&#160;120  mg/kg bw</p><p>STOT SE 3; H335: C &#8805;&#160;5&#160;%</p><p>Skin Irrit. 2; H315: C &#8805;&#160;5&#160;%</p><p>Eye Irrit. 2; H319: C &#8805;&#160;5&#160;%</p></td><td><p>D&#8217;</p></td></tr><tr><td><p>&#8216;607-034-00-0</p></td><td><p>methyl acrylate;</p><p>methyl propenoate</p></td><td><p>202-500-6</p></td><td><p>96-33-3</p></td><td><p>Flam. Liq. 2</p><p>Acute Tox. 3</p><p>Acute Tox. 4</p><p>Acute Tox. 4</p><p>STOT SE 3</p><p>Skin Irrit. 2</p><p>Eye Irrit. 2</p><p>Skin Sens. 1</p></td><td><p>H225</p><p>H331</p><p>H312</p><p>H302</p><p>H335</p><p>H315</p><p>H319</p><p>H317</p></td><td><p>GHS02</p><p>GHS06</p><p>Dgr</p></td><td><p>H225</p><p>H331</p><p>H312</p><p>H302</p><p>H335</p><p>H315</p><p>H319</p><p>H317</p></td><td><p>&#160;</p></td><td><p>inhalation: ATE&#160;= 3 mg/L (vapours)</p><p>dermal: ATE&#160;= 1&#160;100  mg/kg bw</p><p>oral: ATE&#160;= 500 mg/kg bw</p></td><td><p>D&#8217;</p></td></tr><tr><td><p>&#8216;607-223-00-8</p></td><td><p>transfluthrin (ISO); 2,3,5,6-tetrafluorobenzyl (1<span>R</span>,3<span>S</span>)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate</p></td><td><p>405-060-5</p></td><td><p>118712-89-3</p></td><td><p>Carc. 2</p><p>Acute Tox. 4</p><p>STOT SE 1</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H351</p><p>H302</p><p>H370 (nervous system)</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS07</p><p>GHS09</p><p>Wng</p></td><td><p>H351</p><p>H302</p><p>H370 (nervous system)</p><p>H410</p></td><td><p>EUH066</p></td><td><p>oral: ATE&#160;= 580 mg/kg bw</p><p>M&#160;= 1&#160;000</p><p>M&#160;= 1&#160;000 &#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;607-246-00-3</p></td><td><p>allyl methacrylate;</p><p>2-methyl-2-propenoic acid 2-propenyl ester</p></td><td><p>202-473-0</p></td><td><p>96-05-9</p></td><td><p>Flam. Liq. 3</p><p>Acute Tox. 2</p><p>Acute Tox. 3</p><p>Acute Tox. 4</p><p>Aquatic Acute 1</p></td><td><p>H226</p><p>H330</p><p>H311</p><p>H302</p><p>H400</p></td><td><p>GHS02</p><p>GHS06</p><p>GHS09</p><p>Dgr</p></td><td><p>H226</p><p>H330</p><p>H311</p><p>H302</p><p>H400</p></td><td><p>&#160;</p></td><td><p>inhalation: ATE&#160;= 1,5&#160;mg/L (vapours)</p><p>dermal: ATE&#160;= 300 mg/kg bw</p><p>oral: ATE&#160;= 400 mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;612-004-00-5</p></td><td><p>triethylamine</p></td><td><p>204-469-4</p></td><td><p>121-44-8</p></td><td><p>Flam. Liq. 2</p><p>Acute Tox. 3</p><p>Acute Tox. 3</p><p>Acute Tox. 3</p><p>Skin Corr. 1A</p><p>Eye Dam. 1</p></td><td><p>H225</p><p>H331</p><p>H311</p><p>H301</p><p>H314</p><p>H318</p></td><td><p>GHS02</p><p>GHS06</p><p>GHS05</p><p>Dgr</p></td><td><p>H225</p><p>H331</p><p>H311</p><p>H301</p><p>H314</p></td><td><p>&#160;</p></td><td><p>inhalation: ATE&#160;= 7,2&#160;mg/L (vapours)</p><p>dermal: ATE&#160;= 300 mg/kg bw</p><p>oral: ATE&#160;= 100 mg/kg bw STOT SE 3; H335: C &#8805;&#160;1&#160;%&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;612-049-00-0</p></td><td><p>di-<span>n</span>-butylamine</p></td><td><p>203-921-8</p></td><td><p>111-92-2</p></td><td><p>Flam. Liq. 3</p><p>Acute Tox. 2</p><p>Acute Tox. 3</p><p>Acute Tox. 3</p><p>Skin Corr. 1B</p><p>Eye Dam. 1</p></td><td><p>H226</p><p>H330</p><p>H311</p><p>H301</p><p>H314</p><p>H318</p></td><td><p>GHS02</p><p>GHS06</p><p>GHS05</p><p>Dgr</p></td><td><p>H226</p><p>H330</p><p>H311</p><p>H301</p><p>H314</p></td><td><p>EUH 071</p></td><td><p>inhalation: ATE&#160;= 1,2&#160;mg/L (vapours) dermal: ATE&#160;= 300 mg/kg bw</p><p>oral: ATE&#160;= 220 mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;612-056-00-9</p></td><td><p><span>N</span>,<span>N</span>-dimethyl-m-toluidine; [1]</p><p><span>N</span>,<span>N</span>-dimethyl-o-toluidine [2]</p></td><td><p>204-495-6 [1] 210-199-8 [2]</p></td><td><p>121-72-2 [1] 609-72-3 [2]</p></td><td><p>Acute Tox. 3 * Acute Tox. 3 * Acute Tox. 3 * STOT RE 2 * Aquatic Chronic 3</p></td><td><p>H331</p><p>H311</p><p>H301</p><p>H373 **</p><p>H412</p></td><td><p>GHS06 GHS08</p><p>Dgr</p></td><td><p>H331</p><p>H311</p><p>H301</p><p>H373 **</p><p>H412</p></td><td><p>&#160;</p></td><td><p>*</p></td><td><p>C&#8217;</p></td></tr><tr><td><p>&#8216;613-088-00-6</p></td><td><p>1,2-benzisothiazol-3(2H)-one; 1,2-benzisothiazolin-3-one</p></td><td><p>220-120-9</p></td><td><p>2634-33-5</p></td><td><p>Acute Tox. 2</p><p>Acute Tox. 4</p><p>Skin Irrit. 2</p><p>Eye Dam. 1</p><p>Skin Sens. 1A</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H330</p><p>H302</p><p>H315</p><p>H318</p><p>H317</p><p>H400</p><p>H410</p></td><td><p>GHS06</p><p>GHS05</p><p>GHS09</p><p>Dgr</p></td><td><p>H330</p><p>H302</p><p>H315</p><p>H318</p><p>H317</p><p>H410</p></td><td><p>&#160;</p></td><td><p>inhalation:</p><p>ATE&#160;= 0,21&#160;mg/L (dusts or mists)</p><p>oral: ATE&#160;= 450 mg/kg bw</p><p>Skin Sens. 1A; H317: C &#8805;&#160;0,036&#160;%</p><p>M&#160;= 1</p><p>M&#160;= 1&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;613-127-00-7</p></td><td><p>mepiquat chloride (ISO); 1,1-dimethylpiperidinium chloride</p></td><td><p>246-147-6</p></td><td><p>24307-26-4</p></td><td><p>Acute Tox. 4</p><p>Acute Tox. 3</p><p>Aquatic Chronic 3</p></td><td><p>H332</p><p>H301</p><p>H412</p></td><td><p>GHS06</p><p>Dgr</p></td><td><p>H332</p><p>H301</p><p>H412</p></td><td><p>&#160;</p></td><td><p>inhalation: ATE&#160;= 2,8&#160;mg/L (dusts or mists)</p><p>oral:</p><p>ATE&#160;= 270 mg/kg bw&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;613-307-00-5</p></td><td><p>clothianidin (ISO); (E)-1-(2-chloro&#8211;1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine</p></td><td><p>433-460-1</p></td><td><p>210880-92-5</p></td><td><p>Repr. 2</p><p>Acute Tox. 4</p><p>STOT SE 1</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H361f</p><p>H302</p><p>H370 (nervous system)</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS07</p><p>GHS09</p><p>Dgr</p></td><td><p>H361f</p><p>H302</p><p>H370 (nervous system)</p><p>H410</p></td><td><p>&#160;</p></td><td><p>oral: ATE&#160;= 390 mg/kg bw</p><p>M&#160;= 10</p><p>M&#160;= 100&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;616-035-00-5</p></td><td><p>cymoxanil (ISO); 2-cyano-<span>N</span>-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide; [1]</p><p>(2<span>E</span>)-2-cyano-<span>N</span>-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide; [2]</p></td><td><p>261-043-0 [1]</p><p>- [2]</p></td><td><p>57966-95-7 [1]</p><p>166900-80-7 [2]</p></td><td><p>Repr. 2</p><p>Acute Tox. 4</p><p>STOT RE 2</p><p>Skin Sens. 1</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H361fd</p><p>H302</p><p>H373 (blood system, thymus, eyes)</p><p>H317</p><p>H400</p><p>H410</p></td><td><p>GHS08</p><p>GHS07</p><p>GHS09</p><p>Wng</p></td><td><p>H361fd</p><p>H302</p><p>H373 (blood system, thymus, eyes)</p><p>H317</p><p>H410</p></td><td><p>&#160;</p></td><td><p>oral: ATE&#160;= 360 mg/kg bw</p><p>M&#160;= 1</p><p>M&#160;= 1&#8217;</p></td><td><p>&#160;</p></td></tr><tr><td><p>&#8216;616-104-00-X</p></td><td><p>benalaxyl (ISO); methyl<span>N</span>-(2,6-dimethylphenyl)-<span>N</span>-(phenylacetyl)-DL-alaninate</p></td><td><p>275-728-7</p></td><td><p>71626-11-4</p></td><td><p>Acute Tox. 4</p><p>Aquatic Acute 1</p><p>Aquatic Chronic 1</p></td><td><p>H302</p><p>H400</p><p>H410</p></td><td><p>GHS07</p><p>GHS09</p><p>Wng</p></td><td><p>H302</p><p>H410</p></td><td><p>&#160;</p></td><td><p>oral: ATE&#160;= 1&#160;000  mg/kg bw</p><p>M&#160;= 1</p><p>M&#160;= 1&#8217;</p></td><td><p>&#160;</p></td></tr></tbody></table></td></tr></tbody></table>
ELI: http://data.europa.eu/eli/reg_del/2024/197/oj
ISSN 1977-0677 (electronic edition)