Document Classification

Section Type: RESULTS

Text: Among 39 nonresponders who increased their dose to 5 mg/d, response rate was 12. 8 % (95 % CI, 4. 30 % -27. 43 %), with significant overall mean SD reductions in MADRS scores (-9. 46 7. 83 [95 % CI, -12. 00 to -6. 92] ; P <. 0001), Symptoms Questionnaire Distress scores (19. 51 17. 73 [95 % CI, 13. 60 to 25. 43] ; P <. 0001), PHQ-9 scores (-7. 92 5. 92 [95 % CI, -9. 89 to -5. 94] ; P <. 0001), and CGI-S scores (-0. 86 0. 86 [95 % CI, -1. 15 to -0. 58] ; P <. 0001).