Document Classification

Section Type: RESULTS

Text: At the year 5 visit, girls in the intervention group had 29. 8 % (95 % confidence interval [CI] = 5. 4 % to 47. 9 % ; P =. 02) lower estradiol, 30. 2 % (95 % CI = 7. 0 % to 47. 7 % ; P =. 02) lower non-sex hormone binding globulin-bound estradiol, 20. 7 % (95 % CI = 4. 7 % to 34. 0 % ; P =. 02) lower estrone, and 28. 7 % (95 % CI = 5. 1 % to 46. 5 % ; P =. 02) lower estrone sulfate levels during the follicular phase of the menstrual cycle and 27. 2 % (95 % CI = 5. 7 % to 53. 1 % ; P =. 01) higher testosterone levels during the luteal phase of the menstrual cycle than did girls in the usual care group.