Document Classification

Section Type: RESULTS

Text: The use of tiotropium resulted in a superior primary outcome, as compared with a doubling of the dose of an inhaled glucocorticoid, as assessed by measuring the morning peak expiratory flow (PEF), with a mean difference of 25. 8 liters per minute (P < 0. 001) and superiority in most secondary outcomes, including evening PEF, with a difference of 35. 3 liters per minute (P < 0. 001) ; the proportion of asthma-control days, with a difference of 0. 079 (P = 0. 01) ; the forced expiratory volume in 1 second (FEV1) before bronchodilation, with a difference of 0. 10 liters (P = 0. 004) ; and daily symptom scores, with a difference of -0. 11 points (P < 0. 001).