Document Classification

Section Type: RESULTS

Text: By comparison with controls, in patients receiving fish oil, (1) a large increase in eicosapentaenoic acid (20:5 n-3) was observed in both platelet phosphatidylcholine (1. 55 % + / - 0. 17 % vs 0. 38 % + / - 0. 06 % by weight, p <. 01) and phosphatidylethanolamine 2. 21 % + / - 0. 18 % vs 0. 66 % + / - 0. 08 % by weight, p <. 01) ; (2) eicosapentaenoic acid (20:5 n-3) / arachidonic acid (20:4 n-6) ratios doubled in both platelet phosphatidylcholine (p <. 01) and phosphatidylethanolamine (p <. 05) ; (3) with collagen as aggregating factor, maximal reaction speed decreased (p <. 02) and latency increased (p <. 002) ; and (4) no toxic effect, in particular no increase of postoperative bleeding and no perturbation of hepatic and renal function, was observed during the fish oil infusion.