Document Classification

Section Type: RESULTS

Text: Plaques from the pravastatin group had less lipid by oil red O staining (8. 2 + / -8. 4 % versus 23. 9 + / -21. 1 % of the plaque area, P < 0. 05), less oxidized LDL immunoreactivity (13. 3 + / -3. 6 % versus 22. 0 + / -6. 5 %, P < 0. 001), fewer macrophages (15. 0 + / -10. 2 % versus 25. 3 + / -12. 5 %, P < 0. 05), fewer T cells (11. 2 + / -9. 3 % versus 24. 3 + / -13. 4 %, P < 0. 05), less matrix metalloproteinase 2 (MMP-2) immunoreactivity (3. 6 + / -3. 9 % versus 8. 4 + / -5. 3 %, P < 0. 05), greater tissue inhibitor of metalloproteinase 1 (TIMP-1) immunoreactivity (9. 0 + / -6. 2 % versus 3. 1 + / -3. 9 %, P < 0. 05), and a higher collagen content by Sirius red staining (12. 4 + / -3. 1 % versus 7. 5 + / -3. 5 %, P < 0. 005).