Document Classification

Section Type: RESULTS

Text: At the end of the study, the following significant differences [means (95 % CIs)] were seen between the synbiotic and placebo groups, respectively : ALT [-25. 1 (-26. 2, -24) compared with -7. 29 (-9. 5, -5. 1) IU/L ; P < 0. 001], aspartate aminotransferase [-31. 33 (-32. 1, -30. 5) compared with -7. 94 (-11. 1, -4. 8) IU/L ; P < 0. 001], - glutamyltransferase [-15. 08 (-15. 5, -14. 7) compared with -5. 21 (-6. 6, -3. 9) IU/L ; P < 0. 001], high-sensitivity C-reactive protein [-2. 3 (-3, -1. 5) compared with -1. 04 (-1. 5, -0. 6) mmol/L ; P < 0. 05], tumor necrosis factor - [-1. 4 (-1. 7, -1. 1) compared with -0. 59 (-0. 8, -0. 3) mmol/L ; P < 0. 001], total nuclear factor - B p65 [-0. 016 (-0. 022, -0. 011) compared with 0. 001 (-0. 004, -0. 007) mmol/L ; P < 0. 001], and fibrosis score as determined by transient elastography [- 2. 98 (-3. 6, -2. 37) compared with -0. 77 (-1. 32, -0. 22) kPa ; P < 0. 001].