Document Classification

Section Type: METHODS

Text: LM group : dose L (1-min loading dose at a rate of 0. 03 mg/kg/min, followed by a 10-min infusion at 0. 01 mg/kg/min) followed by dose M (1-min loading at a rate of 0. 06 mg/kg/min, followed by a 10-min infusion at 0. 02 mg/kg/min) ; MH group : dose M followed by dose H (1-min loading dose at a rate of 0. 125 mg/kg/min, followed by a 10-min infusion at 0. 04 mg/kg/min) ; placebo (PP) group : dose P (1-min loading dose at a rate of 0 mg/kg/min, followed by a 10-min infusion at 0 mg/kg/min) followed by another round of dose P.