Document Classification

Section Type: RESULTS

Text: Compared with placebo, the S. typhi vaccination caused a rise in white cell count (11. 1 + / - 0. 5 x10 (9) / l vs. 7. 9 + / - 0. 8 x10 (9) / l ; p = 0. 004) and plasma interleukin-6 concentrations (6. 9 + / - 1. 4 pg/ml vs. 1. 6 + / - 0. 4 pg/ml ; p = 0. 01) in addition to a significant augmentation of t-PA antigen (45 + / - 9 ng/100 ml/min at peak dose vs. 24 + / - 8 ng/100 ml/min at peak dose ; p = 0. 016, analysis of variance) and activity (104 + / - 15 IU/100 ml/min vs. 54 + / - 12 IU/100 ml/min ; p = 0. 006, analysis of variance) release during bradykinin infusion.