Document Classification

Section Type: RESULTS

Text: In addition, anastrozole had no clinically significant effect on the pharmacodynamic effects of warfarin, as assessed 240 h after warfarin dosing by measurement of prothrombin time (s) (glsmean, anastrozole 11. 56, placebo 11. 31, 95 % CI 0. 987-1. 059), thrombin time (s) (glsmean, anastrozole 19. 06, placebo 18. 75, 95 % CI 0. 980-1. 054) activated partial thromboplastin time (s) (glsmean, anastrozole 29. 94, placebo 29. 74, 95 % CI 0. 968-1. 047) and factor VII (%) (glsmean, anastrozole 97. 81, placebo 107. 26, 95 % CI 0. 821-1. 012).