Document Classification

Section Type: RESULTS

Text: Prolonged coadministration of N-acetylcysteine and nitroglycerin potentiated the acute venodilator effect of nitroglycerin as estimated by changes in venous volume (nitroglycerin plus N-acetylcysteine, 4. 45 + / - 0. 36 ml/100 g ; nitroglycerin plus placebo, 3. 65 + / - 0. 46 ml/100 g, mean + / - SEM, p < 0. 05) and prevented development of tolerance as seen after 23 h of treatment with nitroglycerin plus placebo (4. 35 + / - 0. 25 vs. 3. 47 + / - 0. 41 ml/100 g, p < 0. 05).