Document Classification

Section Type: METHODS

Text: In a randomized, double-blind study, the authors compared hemodynamic variables (systemic vascular resistance, cardiac index, arterial blood pressure, mean pulmonary artery pressure, central venous pressure) and the requirement of epinephrine during transplantation in 67 patients who received either high-dose aprotinin (2 x 10 (6) kallikrein inhibitor units [KIU] at induction, continuous infusion of 1 x 10 (6) KIU/h, 1 x 10 (6) KIU before reperfusion ; n = 24), regular-dose aprotinin (2 x 10 (6) KIU at induction, continuous infusion of 0. 5 x 10 (6) KIU/h ; n = 21), or placebo (n = 22).