Document Classification

Section Type: RESULTS

Text: The AUC (0, 24 h) and Cmax of ethinyloestradiol remained unchanged during all study cycles, whereas the AUC (0, 24 h) and Cmax of 3-ketodesogestrel decreased significantly from 31. 2 ng ml-1 h to 17. 7 ng x ml-1 h (43. 9 % ; 95 % confidence interval (CI) -49. 3, -38. 5, P = 0. 001) and from 3. 6 ng x ml -1 to 3. 0 ng x ml -1 (17. 8 % ; CI -29. 9, -5. 7, P = 0. 005), respectively, during cycle A and by 41. 7 % (CI -47. 9, -35. 6 ; P = 0. 001) and by 22. 8 % (CI -31. 2, -13. 3 ; P < 0. 001) during cycle B respectively, compared with the control cycle.