Document Classification

Section Type: RESULTS

Text: At final follow-up, allocation to B-vitamins, compared with placebo, was associated with a reduction in mean tHcy (10. 2 mol/L versus 14. 2 mol/L ; P < 0. 001) but no change from baseline in the mean MMSE score (-0. 22 points versus -0. 25 points ; difference, 0. 03 ; 95 % confidence interval, -0. 13 to 0. 19 ; P = 0. 726) and no difference in the incidence of cognitive impairment (5. 51 % versus 5. 47 % ; risk ratio, 1. 01 ; 95 % confidence interval, 0. 69-1. 48 ; P = 0. 976), cognitive decline (9. 1 % versus 10. 3 % ; risk ratio, 0. 89 ; 0. 67-1. 18 ; P = 0. 414), or cognitive impairment or decline (11. 0 % versus 11. 3 % ; risk ratio, 0. 98 ; 0. 75-1. 27 ; P = 0. 855).