Document Classification

Section Type: RESULTS

Text: However, in contrast an activation of the CYP450 enzyme system was observed in group B after 28 days of fusidic acid therapy with an increase of total antipyrine clearance (43. 0 + / - 7. 62 ml/min to 51. 0 + / - 9. 03 ml/min) as well as clearances to all metabolites (NORA 7. 11 + / - 1. 75 to 8. 60 + / -2. 10 ml/min, OHA 11. 5 + / - 2. 89 to 14. 0 + / - 3. 97 ml/min, HMA 4. 05 + / - 0. 99 to 4. 94 + / - 1. 27 ml/min).