Document Classification

Section Type: RESULTS

Text: The ratios of the area under the plasma concentration-time curves from time 0 to infinity (AUC (0-infinity) of omeprazole to 5-hydroxyomprazole and those of omeprazole to omeprazole sulfone decreased by 64. 80 % + / -12. 51 % (P = 0. 001) and 63. 31 % + / -18. 45 % (P = 0. 004) in CYP2C19 * 1 / * 1, 57. 98 % + / -14. 80 % (P = 0. 002) and 54. 87 % + / -18. 42 % (P = 0. 003) in CYP2C19 * 1 / * 2 or * 3, and 37. 74 % + / -16. 07 % (P = 0. 004) and 45. 16 % + / -15. 54 % (P = 0. 003) in CYP2C19 * 2 / * 2, respectively.