Document Classification

Section Type: RESULTS

Text: A single dose of rifampin significantly increased the mean area under the plasma concentration-time curve (AUC) (0-48 h) and Cmax of pitavastatin by 573. 5 % (95 % CI, 373. 3-773. 7 %, p < 0. 001) and 819. 2 % (95 % CI, 515. 4-1123. 0 %, p < 0. 001) respectively, while significantly decreased the t1/2 and CL/F of pitavastatin by 38. 8 % (95 % CI, 18. 2-59. 4 %, p < 0. 001) and 81. 4 % (95 % CI, 75. 0-87. 7 %, p < 0. 001) respectively.