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Section Type: RESULTS

Text: Pharmacokinetic parameters C (max, ss) and AUC (0, 24 h) (ss) at steady state were similar with or without co-administration of rotigotine for both ethinyloestradiol and levonorgestrel with geometric mean ratios close to 1 and 90 % confidence intervals within the acceptance range of bioequivalence (0. 8, 1. 25) : C (max, ss) 1. 05 (0. 93, 1. 19), AUC (0, 24 h) (ss) 1. 05 (0. 9, 1. 22) for ethinyloestradiol ; C (max, ss) 1. 01 (0. 96, 1. 06), AUC (0, 24 h) (ss) 0. 98 (0. 95, 1. 01) for levonorgestrel.