Document Classification

Section Type: METHODS

Text: In a cross-over randomized controlled trial, 33 non-diabetic CKD patients (proteinuria 3. 8 0. 4 g/24 h, blood pressure 143/86 3/2 mmHg, creatinine clearance 89 5 mL/min) were treated during 6-week periods with placebo, angiotensin receptor blockade (ARB ; losartan 100 mg/day) and ARB plus diuretics (losartan 100 mg/day plus hydrochlorothiazide 25 mg/day), combined with LS (93 52 mmol Na (+) / 24 h) and regular sodium diet (RS ; 193 62 mmol Na (+) / 24 h, P < 0. 001 versus LS), in random order.