Document Classification

Section Type: RESULTS

Text: When compared with placebo, metformin treatment was associated with an increase in urinary albumin excretion of 21 % (-1 to +48 ; P = 0. 06) ; a decrease in plasma von Willebrand factor of 6 % (-10 to -2 ; P = 0. 0007) ; a decrease in soluble vascular cell adhesion molecule-1 of 4 % (-7 to -2 ; P = 0. 0002) ; a decrease in soluble E-selectin of 6 % (-10 to -2 ; P = 0. 008) ; a decrease in tissue-type plasminogen activator of 16 % (-20 to -12 ; P < 0. 0001) ; and a decrease in plasminogen activator inhibitor-1 of 20 % (-27 to -10 ; P = 0. 0001).