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Section Type: RESULTS

Text: Using glucose infusion rate (GIR) parameters, detemir showed a flatter pharmacodynamic profile versus NPL : area under the curve, AUC (GIR) ((0-32)) = 1326 vs. 1841 mg/kg, p < 0. 01 (detemir vs. NPL, respectively) ; AUC (GIR) ((0-12)) = 784 vs. 1392 mg/kg, p < 0. 05 ; AUC (GIR) ((12-32)) = 455 vs. 274 mg/kg, p = 0. 051 ; GIR (late) (12-32) / GIR (early) (0-12) ratio = 0. 33 vs. 0. 04, p < 0. 001.