Document Classification

Section Type: RESULTS

Text: Plasma methotrexate pharmacokinetics (AUC (0-t), maximum concentration [C (max)], time to C (max)) and methotrexate protein binding were similar for methotrexate alone (108. 0 ng. h / mL, 26. 7 ng/mL, 1. 5 h, and 57. 1 %, respectively), methotrexate/lumiracoxib (110. 2 ng. h / mL, 27. 5 ng/mL, 1. 0 h, and 53. 7 %, respectively), and methotrexate/placebo (101. 8 ng. h / mL, 22. 6 ng/mL, 1. 0 h, and 57. 0 %, respectively).