Document Classification

Section Type: RESULTS

Text: After the 600-mg loading dose, Cmax values (mean + / - SD) of clopidogrel and its active metabolite in 3435T/T carriers were 13. 3 + / -5. 2 ng/mL and 2. 5 + / -1. 2 ng/mL, respectively, compared with 49. 7 + / -41. 6 ng/mL (P =. 001) and 6. 6 + / -3. 6 ng/mL (P =. 011), respectively, in 3435C/T and 3435C/C carriers ; AUC values were 1502 + / -463 ng/mLxmin for clopidogrel and 209 + / -99 ng/mL x min for its active metabolite in 3435T/T carriers compared with 7057 + / -5443 ng/mLxmin (P =. 0006) and 744 + / -541 ng/mLxmin (P =. 011), respectively, in 3435C/T and 3435C/C carriers.