Document Classification

Section Type: RESULTS

Text: Dobutamine dose-dependently increased ventilation (placebo 6. 7 + / - 0. 5 vs. D2. 5 7. 8 + / - 0. 4 vs. D7. 5 8. 7 + / - 0. 4 l min (-1), P < 0. 005) during normoxia, enhanced the ventilatory (placebo 14. 4 + / - 0. 6 vs. D2. 5 17. 3 + / - 0. 8 vs. D7. 5 22. 5 + / - 1. 9 l min (-1), P < 0. 0001) and sympathetic (placebo + 215 + / - 31 vs. D2. 5 + 285 + / - 19 vs. D7. 5 + 395 + / - 50 % of baseline, P < 0. 03) responses at the fifth minute of isocapnic hypoxia and enhanced the sympathetic response to apnoea performed after hypoxia (increase after 5 min of hypoxia : + 290 + / - 43 % for placebo vs. + 360 + / - 21 % for D2. 5 vs. 537 + / - 69 % for D7. 5, P < 0. 05).