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Section Type: RESULTS

Text: Amprenavir mean area under the curve over 12 h (AUC0-12 h) and concentration at 12 h (C12 h) (microg/ml) were, respectively, 42. 7 microg x h/ml (range, 33. 1-55. 1) and 2. 4 microg/ml (range, 1. 4-3. 2) in arm B and 17. 4 microg x h/ml (range, 4. 6-41. 3) and 0. 9 microg/ml (range, 0. 2-2. 7) in arm C : geometric mean ratio (GMR) arm C : B was 0. 36 [99. 9 % upper confidence boundary (UCB), 0. 64] and 0. 31 (99. 9 % h UCB, 0. 61), respectively (P < or = 0. 0001).