Document Classification

Section Type: RESULTS

Text: Twenty-one partial responses (52. 5 %, median duration 7. 2 months) were observed with the IRINOX arm and two complete and 20 partial responses (55 %, median duration 6. 4 months) with arm B. Median progression-free and overall survival times were 8. 4 and 19 months, respectively, in the IRINOX arm and 8. 1 and 20. 4 months in arm B. Main grade 3/4 toxic effects were, respectively, neutropenia 42. 5 % and 32. 5 % ; febrile neutropenia 10 % and 5 % ; diarrhea 32. 5 % and 7. 5 % ; vomiting 10. 0 % and 5 % ; neurosensory toxicity 17. 5 % and 7. 5 %.