Document Classification

Section Type: METHODS

Text: Thirty-nine patients with normal renal function (65 + / - 9 years, serum creatinine 0. 9 + / - 0. 2 mg/dl, GFR = 110 + / - 31 ml/min/1. 73 m2) receiving at least 80 ml of low-osmolality CM during an angiographic procedure were randomized to one of the following hydration regimens : Group 1 : volume expansion with 300 ml saline during CM administration (n = 20, serum creatinine 0. 8 + / - 0. 1 mg/dl, GFR 119 + / - 27 ml/min/1. 73 m2) ; Group 2 : intravenous administration of at least 2, 000 ml saline within 12 h before and after CM application (n = 19, serum creatinine 0. 9 + / - 0. 2 mg/dl, GFR 101 + / - 32 ml/min/1. 73 m2).