Document Classification

Section Type: RESULTS

Text: In the 18 refractory UC patients with platelet activation, after more than 4 wk of combined Kangshuanling and sulfasalazine therapy, 16 patients achieved clinical remission, with a highly significant statistical difference (P < 0. 01) between pre-and post-treatment mean scores for all disease parameters : stool frequency (8. 2 / d vs 1. 6 / d), rectal bleeding (score 2. 7 vs 0. 3), colonoscopy (score 2. 6 vs 1. 1), histology (score 12. 0 vs 5. 0), general well being (score 4. 0 vs 0. 6) and CD62p (8. 0 + / -3. 1 % vs 4. 1 + / -1. 8 %), CD63 (6. 3 + / -2. 1 % vs 3. 2 + / -1. 6 %), TXA2 (548 + / -85 ng/L vs 390 + / -67 ng/L), platelet aggregation rate (43. 2 + / -10. 7 % vs 34. 8 + / -8. 1 %), thrombosis length in vitro (2. 3 + / -0. 6 cm vs 1. 8 + / -0. 3 cm), CD54 in blood (26. 9 + / -6. 9 % vs 14. 4 + / -5. 1 %), CD54 in tissues (51. 1 + / -6. 2 % vs 23. 1 + / -4. 1 %), Pgp-170 in blood (18. 9 + / -3. 9 % vs 10. 4 + / -2. 7 %), Pgp-170 in tissues (16. 5 + / -3. 2 % vs 10. 2 + / -2. 3 %, P < 0. 01 or 0. 05).