Document Classification

Section Type: RESULTS

Text: In a backward Cox regression procedure that included risk factors and biomarkers, Nt-proBNP (hazard ratio [HR] 1. 72 per increment SD, 95 % CI 1. 39 to 2. 12 ; P < 0. 0001), soluble intercellular adhesion molecule-1 (HR 1. 46, 95 % CI 1. 19 to 1. 80 ; P = 0. 0003), microalbuminuria (HR 1. 55, 95 % CI 1. 22 to 1. 98 ; P = 0. 0004), soluble interleukin-1 receptor antagonist (HR 1. 30, 95 % CI 1. 05 to 1. 61 ; P = 0. 02), and fibrinogen (HR 1. 31, 95 % CI 1. 05 to 1. 62 ; P = 0. 02) remained significantly related to the primary outcome.