Document Classification

Section Type: RESULTS

Text: Compared with placebo, nesiritide was associated with a significantly attenuated peak increase in serum creatinine (0. 15 + / - 0. 29 mg/dl vs. 0. 34 + / - 0. 48 mg/dl ; p < 0. 001) and a smaller fall in glomerular filtration rate (-10. 8 + / - 19. 3 ml/min/1. 73 m (2) vs. -17. 2 + / - 21. 9 ml/min/1. 73 m (2) ; p = 0. 001) during hospital stay or by study day 14, and a greater urine output (2, 926 + / - 1, 179 ml vs. 2, 350 + / - 1, 066 ml ; p < 0. 001) during the initial 24 h after surgery.