Document Classification

Section Type: RESULTS

Text: The mean maximum changes from baseline during GTN infusion for subjects administered with either NMI 861 or placebo were a decrease of 16. 9 + / - 3. 4 vs 13. 6 + / - 2. 4 mmHg (mean difference between treatments -3. 3 mmHg, 95 % CI -12. 7, 6. 0 mmHg (P = 0. 460)) for SBP, a decrease of 14. 7 + / - 2. 0 vs 14. 0 + / - 2. 0 mmHg for DBP (mean difference -0. 7 mmHg, 95 % CI -8. 2, 6. 8 mmHg (P = 0. 835)), and an increase of 11. 8 + / - 1. 9 vs 14. 1 + / - 2. 4 beats min (-1) for pulse, respectively (mean difference -2. 3 beats min (-1), 95 % CI -9. 3, 4. 5 beats min (-1) (P = 0. 464)).