Document Classification

Section Type: RESULTS

Text: The study met all 3 noninferiority primary objectives : (1) the percentage of aCRT patients who improved in their clinical composite score at 6 months was at least as high in the aCRT arm as in the Echo arm (73. 6 % vs 72. 5 %, with a noninferiority margin of 12 % ; P =. 0007) ; (2) aCRT and echo-optimized settings resulted in similar cardiac performance, as demonstrated by a high concordance correlation coefficient between aortic velocity time integrals at aCRT and Echo settings at randomization (concordance correlation coefficient = 0. 93 ; 95 % confidence interval 0. 91-0. 94) and at 6-month postrandomization (concordance correlation coefficient = 0. 90 ; 95 % confidence interval 0. 87-0. 92) ; and (3) aCRT did not result in inappropriate device settings.