Document Classification

Section Type: RESULTS

Text: Nortriptyline significantly reduced the acid-induced brain response in prefrontal cortex (median [IQR] : -1. 9 [-4. 5 to -0. 1] vs -0. 3 [-2. 5 to 2. 3] ; p = 0. 050), caudate (-3. 0 [-5. 1 to -0. 01] vs 0. 48 [-1. 9 to 3. 1] ; p = 0. 029), insula (-2. 4 [-4. 8 to -0. 6] vs -0. 2 [-1. 5 to 1. 5] ; p = 0. 029), cingulate (-4. 2 [-8. 8 to -0. 1] vs -0. 6 [-1. 8 to 3. 0] ; p = 0. 017), and hippocampus (-2. 7 [-6. 0 to 0. 5] vs -0. 04 [-2. 3 to 1. 9] ; p = 0. 006) in comparison with placebo.