Document Classification

Section Type: RESULTS

Text: Insulin sensitivity, as assessed by homeostasis model assessment (2. 20 + / - 1. 62 vs. 3. 61 + / - 1. 87, P = 0. 01), or the change of insulin sensitivity index from baseline to study end (0. 021 + / - 0. 023 vs. -0. 003 + / - 0. 012 micromol x kg (-1) x min (-1) per pmol/l, P = 0. 0001) and beta-cell function (57. 42 + / - 49. 86 vs. 21. 78 + / - 18. 54 mU/l per mmol/l, P = 0. 0014) significantly improved in the pioglitazone group, with no change observed after placebo.