Document Classification

Section Type: RESULTS

Text: Both in the short and long term (completed by 13 patients), on TMZ compared to placebo, ejection fraction (47 + / - 7 vs 41 + / - 9 and 45 + / - 8 vs 36 + / - 8 %, P <. 001 for both) and M value (4. 0 + / - 1. 8 vs 3. 3 + / - 1. 6, P =. 003, and 3. 5 + / - 1. 5 vs 2. 7 + / - 1. 6 mg/kg body weight/min, P <. 01) increased, while fasting blood glucose (121 + / - 30 vs 136 + / - 40, P =. 02 and 125 + / - 36 vs 140 + / - 43, P =. 19) and endothelin-1 (8. 8 + / - 3. 8 vs 10. 9 + / - 3. 8, P <. 001 and 6. 2 + / - 2. 4 vs 9. 2 + / - 4. 3 pg/mL, P =. 03) decreased.