Document Classification

Section Type: RESULTS

Text: Irrespective of concomitant aspirin use, apixaban reduced stroke or systemic embolism [with aspirin : apixaban 1. 12 % vs. warfarin 1. 91 %, hazard ratio (HR) 0. 58, 95 % confidence interval (CI) 0. 39-0. 85 vs. without aspirin : apixaban 1. 11 % vs. warfarin 1. 32 %, HR 0. 84, 95 % CI 0. 66-1. 07 ; P interaction = 0. 10] and caused less major bleeding than warfarin (with aspirin : apixaban 3. 10 % vs. warfarin 3. 92 %, HR 0. 77, 95 % CI 0. 60-0. 99 vs. without aspirin : apixaban 1. 82 % vs. warfarin 2. 78 %, HR without aspirin 0. 65, 95 % CI 0. 55-0. 78 ; P interaction = 0. 29).