Document Classification

Section Type: METHODS

Text: Patients in the treatment groups were premedicated with the following H1 + H2 receptor antagonists : Group 1 (n = 335) : 5 mg/kg cimetidine i. v. + 0. 1 mg/kg dimetindene i. v. 20 min before induction of anaesthesiaGroup 2 (n = 337) : 1. 25 mg/kg ranitidine i. v. + 0. 1 mg/kg dimetindene i. v. 20 min before induction of anaesthesiaGroup 3 (n = 316) : 300 mg ranitidine p. o. + 0. 1 mg/kg dimetindene i. v. 1 to 2 h before induction of anaesthesiaGroup 4 (n = 161) : 20 ml saline solution i. v. 20 min before induction of anaesthesiaPatients from the treatment groups 1, 2 and 3 received regional or general anaesthesia depending on the clinical decision.