Document Classification

Section Type: RESULTS

Text: After 6 months of TMZ treatment, no changes were observed in LVEF (31 10 % vs 34 8 % ; P =. 8), 6MWT (443 25 m vs 506 79 m ; P =. 03), maximum O2 uptake (19. 1 5. 0 mL kg (-1) min (-1) vs 23. 0 7. 2 mL kg (-1) min (-1) ; P =. 11), functional class (percentages of patients in functional classes I/II/III / IV 10/3753/0 vs 7/40/50 / 3 ; P =. 14), or quality of life (32 26 points vs 24 18 points ; P =. 25) in TMZ versus placebo, respectively.