Document Classification

Section Type: RESULTS

Text: In the combined models, dose and baseline score were independently associated with reduction in IVH score, which was quickest in the midline ventricles, then the anterior half of the lateral ventricles and slowest in the posterior half of the lateral ventricles (clearance to 50 % : P < 0. 0001 ; rtPA dose : hazard ratio, 1. 47, 1. 30-1. 67 ; midline versus anterolateral hazard ratio, 1. 71, 1. 08-2. 71 ; midline versus posterolateral hazard ratio, 4. 05, 2. 46-6. 65 ; baseline score hazard ratio, 0. 96, 0. 91-1. 01) with a significant interaction between dose and ventricular region (P = 0. 005).