Document Classification

Section Type: RESULTS

Text: Steady-state etravirine pharmacokinetic parameters were significantly lower after efavirenz intake in the once-daily and twice-daily arms : geometric mean ratios and 90 % confidence intervals were 0. 71 (0. 62 to 0. 81) for AUC 0-24, 0. 78 (0. 70 to 0. 86) for Cmax, 0. 67 (0. 49 to 0. 91) for Ctrough for once daily ; and 0. 72 (0. 63 to 0. 81) for AUC 0-12, 0. 79 (0. 70 to 0. 90) for Cmax, and 0. 63 (0. 54 to 0. 73) for Ctrough for twice daily.