Document Classification

Section Type: RESULTS

Text: Significant reductions from baseline to the final on-treatment assessment on the oppositional subscale of the CPRS-R : L were seen with GXR plus psychostimulant compared with placebo plus psychostimulant, both in the overall study population (placebo-adjusted least squares [LS] mean change from baseline to the final on-treatment assessment : GXR a. m. + psychostimulant, -2. 4, p = 0. 001 ; GXR p. m. + psychostimulant, -2. 2, p = 0. 003) as well as in the subgroup of subjects with significant baseline oppositional symptoms (GXR a. m. + psychostimulant, -3. 6, p = 0. 001 ; GXR p. m. + psychostimulant, -2. 7, p = 0. 013).