Document Classification

Section Type: RESULTS

Text: In TRANSCEND, in the comparison of angiotensin receptor blocker with placebo, there was a significant interaction for the main renal outcome (P = 0. 01) in the direction of harm for patients with normoalbuminuria (0. 37 versus 0. 16 events per 100 patient-years ; hazard ratio, 2. 35 ; confidence interval, 1. 33 to 4. 15) but a trend to benefit with microalbuminuria (0. 52 versus 0. 89 events per 100 patient-years ; hazard ratio, 0. 60 ; confidence interval, 0. 25 to 1. 46) and macroalbuminuria (1. 57 versus 2. 60 events per 100 patient-years ; hazard ratio, 0. 71 ; confidence interval, 0. 21 to 2. 44).