Document Classification

Section Type: RESULTS

Text: We observed a significant upregulation of the markers of cholesterol absorption (campesterol : +16. 8 %, P < 0. 001) and a downregulation of the markers of cholesterol synthesis (lanosterol : -16. 5 %, P = 0. 008) during the active weight-loss phase (first 6 mo, weight loss of 5 %, 6 %, and 10 % in the 3 diet groups, respectively), followed by a rebound (campesterol : -6. 2 %, P = 0. 045 ; lanosterol : +43. 7 %, P < 0. 001) during the next 18 mo (weight gain of 1 %, 1 %, and 2 % in the 3 diet groups, respectively).