Document Classification

Section Type: RESULTS

Text: The selectivity index (SI ; calculated as the ratio of immunoglobulin G to albumin clearance) was slightly and not significantly reduced in patients treated with T plus V from a median of 0. 20 (interquartile range, 0. 13) to 0. 16 (interquartile range, 0. 15 ; P = not significant), whereas it significantly increased from 0. 20 (interquartile range, 0. 14) to 0. 30 (interquartile range, 0. 14 ; P = 0. 0001) in patients treated with T plus A. Modifications in SI and serum creatinine levels at the end of the study from randomization were significantly directly correlated (r = 0. 45 ; P = 0. 001).