Document Classification

Section Type: RESULTS

Text: At weeks 2, 4, and 6, statistically significant treatment differences in changes from baseline were detected using water displacement (mean [90 % CI] treatment differences, +39. 0 g [+17. 9 to +60. 1], +61. 9 g [+36. 1 to +87. 6], and +72. 2 g [+42. 3 to +102. 1], respectively ; all, P 0. 001), ankle circumference (+4. 74 mm [+2. 38 to +7. 11 ; P < 0. 001], +2. 92 mm [+0. 33 to +5. 49 ; P = 0. 032], and +5. 16 mm [+2. 21 to +8. 11 ; P = 0. 002]), and bioimpedance (-11. 7 [-18. 1 to -5. 4], -18. 3 [-26. 2 to -10. 4], and -20. 9 [-29. 7 to -12. 0] ; all, P0. 001), but no significant differences were detected using clinical assessment of pitting.