Document Classification

Section Type: RESULTS

Text: Darusentan significantly reduced diastolic (mean difference to placebo : 10 mg : -3. 7 mm Hg, 95 % confidence interval (CI) : -6. 6, -0. 9, P =. 009 ; 30 mg : -4. 9 mm Hg, 95 % CI : -7. 7, -2. 2, P =. 0005 ; 100 mg : -8. 3 mm Hg, 95 % CI : -11. 1, -5. 5, P =. 0001) and systolic BP (mean difference to placebo : 10 mg : -6. 0 mm Hg, 95 % CI : -11. 0, -0. 9, P =. 02 ; 30 mg : -7. 3 mm Hg, 95 % CI : - 12. 3, -2. 4, P =. 004 ; 100 mg : - 11. 3 mm Hg, 95 % CI : -16. 3, -6. 2, P =. 0001).