Document Classification

Section Type: RESULTS

Text: In multivariable Cox analyses, adjusting for randomized treatment, age, sex, race, prior anti-hypertensive therapy, baseline uric acid, serum creatinine and glucose entered as standard covariates, and in-treatment non-HDL cholesterol, Cornell product left ventricular hypertrophy, diastolic and systolic pressure, BMI, hydrochlorothiazide and statin use as time-varying covariates, the lowest quartile of in-treatment HDL remained associated with a nearly 9-fold increased risk of new diabetes (hazard ratio 8. 7, 95 % CI 5. 0-15. 2), whereas the risk of new diabetes was significantly attenuated for baseline HDL < 1. 21 mmol/l (hazard ratio 3. 9, 95 % CI 2. 8-5. 4).