Document Classification

Section Type: RESULTS

Text: At Week 9, quetiapine XR (least squares [LS] means : -16. 33, standard error [SE] : 0. 95 ; mean change : -16. 0, standard deviation [SD] : 9. 3) significantly reduced MADRS total score from randomization versus placebo (LS means [SE] : -8. 79 [0. 94] ; mean [SD] : -9. 0 [9. 9]) ; significant improvements were also seen at Week 1 (LS means [SE] : -4. 65 [0. 53] versus-2. 56 [0. 53], respectively ; mean [SD] : -4. 3 [5. 1] versus-2. 4 [3. 7], respectively).