Document Classification

Section Type: RESULTS

Text: Orlistat treatment was also associated with significantly greater reductions in haemoglobin A (1c) (-1. 1 % vs. -0. 2 % ; P < 0. 0001), fasting plasma glucose (-1. 9 mmol/l vs. -0. 3 mmol/l ; P < 0. 0001), total cholesterol (-0. 2 mmol/l vs. 0. 1 mmol/l ; P = 0. 03) and apolipoprotein B (-0. 08 g/l vs. 0. 01 g/l ; P = 0. 0085) and greater improvements in beta-cell function (P = 0. 031) and insulin resistance (P = 0. 001) assessed using the homeostasis model assessment (HOMA).