Document Classification

Section Type: METHODS

Text: Percentages of remitters (ie, a score of 7 in the 17-item Hamilton Depression Rating Scale [HDRS-17]) and HDRS-17 score changes from baseline to week 6 were compared in the following 2 pairs, using Fisher exact test or mixed-effects model for repeated measures : (1) subjects who failed to show a 20 % decrease in the HDRS-17 total scores at week 1 but were assigned to continue 15 mg/d (stay (15) group) versus those who were assigned to increase the dose to 30 mg/d (increase (30) group) and (2) subjects who failed to show a 20 % decrease in the HDRS-17 total scores with 30 mg/d at week 2 but were assigned to continue 30 mg/d (stay (30) group) versus those who were assigned to increase the dose to 45 mg/d (increase (45) group).