Document Classification

Section Type: RESULTS

Text: The serum concentrations of PICP (202. 6 + / -11. 5 vs 116. 3 + / -5. 4 microg/l ; mean + / - s. e. m.) and ICTP (10. 5 + / -0. 6 vs 4. 4 + / -0. 3 microg/l) doubled (P < 0. 001) during the first 6 months of GH treatment but returned to baseline by the end of the study (130. 0 + / -10. 4 and 5. 6 + / -0. 7 microg/l respectively), despite constantly elevated serum IGF-I levels (39. 6 + / -4. 1 nmol/l at 42 months vs 11. 9 + / -0. 9 nmol/l at baseline ; P < 0. 001).