Document Classification

Section Type: RESULTS

Text: In the Cox multivariable analyses adjusting for the known predictive value of in-treatment ECG left ventricular hypertrophy by the Cornell product and Sokolow-Lyon voltage, in-treatment QRS duration, systolic and diastolic pressure, incident myocardial infarction and atrial fibrillation, randomized treatment and other risk factors for HF, regression of strain [hazards ratio (HR) 2. 4, 95 % confidence interval (CI) 1. 2-5. 0], persistence of strain (HR 1. 9, 95 % CI 1. 2-3. 2), and development of new ECG strain (HR 2. 3, 95 % CI 1. 2-4. 4) were all independently associated with an increased risk of new HF compared with the absence of ECG strain on both baseline and year-1 ECGs.