Document Classification

Section Type: METHODS

Text: In four consecutive days, nine patients with CAD each received one of the following four regimens : 1) one tablet of placebo the evening before and at 8 AM and 4 PM on the day of the study, 10 ml of saline in a bolus 10 min before exercise, followed by an infusion of the same preparation ; 2) placebo at the same times as in the first regimen, 5, 000 IU of heparin 10 min before exercise, followed by 1, 000 IU/h ; 3) 20 mg TMZ at the same times as in the first regimen, 5, 000 IU of heparin 10 min before exercise, followed by 1, 000 IU/h ; or 4) TMZ at the same times as in the first regimen, 10 ml of saline 10 min before exercise, followed by an infusion of the same preparation.