Document Classification

Section Type: RESULTS

Text: In response to oral administration of a single dose of study drug, the change in flow-mediated vasodilation after release of 1, 3 and 5 min of arterial occlusion was significantly greater in patients receiving sildenafil 25 mg (3. 3 + / - 1. 9, 3. 8 + / - 1. 8 and 4. 0 + / - 1. 8 %, respectively, p < 0. 05) and patients receiving sildenafil 50 mg (3. 7 + / - 1. 3, 4. 1 + / - 1. 1, 3. 9 + / - 1. 3 %, respectively, p < 0. 05) than that of patients receiving placebo (0. 7 + / - 1. 1, 0. 2 + / - 1. 2, 0. 6 + / - 0. 8 %, respectively).