Document Classification

Section Type: RESULTS

Text: The coadministration of oxaliplatin did not significantly alter 5FU area under the plasma concentration-time curve from 0 to 1 hour, area under the plasma concentration-time curve from time 0 to the last time point, or steady-state concentration in either the de Gramont (11. 6 + / - 3. 8 mg/L x h (-1), 14. 9 + / - 4. 2 mg x h/L, and 0. 17 + / - 0. 06 mg/L, respectively, for 5FU alone versus 9. 4 + / - 2. 6 mg/L x h (-1), 13. 3 + / - 2. 3 mg x h/L, and 0. 16 + / - 0. 04, respectively, for 5FU plus oxaliplatin) or modified de Gramont regimens (13. 4 + / - 2. 2 mg x h/L, 35. 4 + / - 4. 2 mg x h/L, and 0. 46 + / - 0. 08 mg/L, respectively, for 5FU alone versus 13. 9 + / - 3. 3 mg x h/L, 38. 1 + / - 7. 4 mg x h/L, and 0. 53 + / - 0. 12, respectively, for 5FU plus oxaliplatin).