Document Classification

Section Type: RESULTS

Text: After the treatment with bifendate, the areas under the curve (AUC (0-24) and AUC (0-infinity)) decreased significantly by 9. 7 % + / -3. 7 % (P = 0. 01) and 19. 2 % + / -16. 8 % (P = 0. 001) in CYP3A4 * 1 / * 1 subjects, 11. 3 % + / -9. 4 % (P = 0. 03) and 10. 5 % + / -9. 6 % (P = 0. 043) in CYP3A4 * 1 / * 18B subjects, and 40. 2 % + / -14. 7 % (P = 0. 02) and 37. 5 % + / -15. 8 % (P = 0. 003) in CYP3A4 * 18B / * 18B subjects.