Document Classification

Section Type: RESULTS

Text: Efficacy assessed in the first 6 days of therapy showed greatest response to rofecoxib, 25 mg/d, followed by rofecoxib, 12. 5 mg/d, celecoxib, and acetaminophen, respectively, in terms of relief of pain on walking (-32. 2, - 29. 0, - 26. 4, and -20. 6 mm change on the VAS ; P < / =. 04 for all others vs acetaminophen ; P =. 05 for 25-mg rofecoxib vs celecoxib), rest pain (-21. 8, - 18. 6, - 15. 5, and - 12. 5 mm ; P < / =. 02 for either dose of rofecoxib vs acetaminophen and P =. 02 for rofecoxib, 25 mg/d, vs celecoxib), night pain (-25. 2, - 22. 0, - 18. 7, and - 18. 8 mm ; P =. 04 for rofecoxib, 25 mg/d, vs both acetaminophen and celecoxib), and morning stiffness (-30. 4, - 28. 4, - 25. 7, and - 20. 9 mm ; P < / =. 02 for either dose of rofecoxib vs acetaminophen).