Document Classification

Section Type: METHODS

Text: between January 2008 and June 2008, a graded maximal exercise test with respiratory gas analysis and an endurance test with constant workload corresponding to 85 % of the peak VO (2) at the baseline and after 3 months were performed, and at the same times, N-terminal probrain natriuretic peptide (NT-proBNP) levels were also measured, in 60 pts (45 M, 15 F, mean age 52. 7 5. 3 years), with stable ischemic CHF, New York Heart Association (NYHA) functional classes II (n = 35) - III (n = 25), with left ventricular ejection fraction (LVEF) 40 %, randomized to a '' off-label '' ivabradine use (n = 30) and a control group (n = 30).