Document Classification

Section Type: RESULTS

Text: In contrast, a significant (P <. 001) increase in serum TXB (2) level was detected on day 7 before drug administration (median, 19. 13 ng/mL [range, 1-47. 5 ng/mL]) and at 24 hours after the coadministration of aspirin and ibuprofen (median, 22. 28 ng/mL [range, 4. 9-44. 4 ng/mL]) versus baseline (median, 1. 65 ng/mL [range, 0. 55-79. 8 ng/mL]) ; this was associated with a significant increase in arachidonic acid-induced platelet aggregation (P <. 01) and adenosine diphosphate-induced platelet aggregation (P <. 05) and a decrease in the time to form an occlusive thrombus in the platelet function analyzer (P <. 01).