Document Classification

Section Type: RESULTS

Text: At week 12, mean changes in LDL cholesterol levels were -67 mg/dL (-41 % ; 95 % CI, -49 % to -33 %) for the AMG145, 280-mg, group ; -70 mg/dL (-43 % ; 95 % CI, -51 % to -35 %) for the 350-mg group ; -91 mg/dL (-51 % ; 95 % CI, -59 % to -43 %) for the 420-mg group ; and -110 mg/dL (-63 % ; 95 % CI, -71 % to -55 %) for the 420-mg/ezetimibe group compared with -14 mg/dL (-15 % ; 95 % CI, -23 % to -7. 0 %) for the placebo/ezetimibe group (P <. 001).