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Section Type: RESULTS

Text: Treatment with sulphonylureas and insulin resulted in similar improvements in glycaemic control (glycated haemoglobin, baseline : 11. 8 [(SD 2. 2) % ; after sulphonylureas : 8. 6 (1. 2) %, p < 0. 001 ; after insulin : 8. 6 (1. 2) %, p < 0. 001] and in insulin sensitivity metabolic clearance rate of glucose, baseline : median 1. 75 [interquartile (IQ) range 1. 41, 2. 27] ml x kg (-1) x min (-1) ; after sulphonylureas : 2. 41 (1. 82, 3. 01) ml x kg (-1) x min (-1), p = 0. 001 ; after insulin : 2. 23 (1. 92, 2. 75) ml x kg (-1) min (-1), p = 0. 027.