Document Classification

Section Type: METHODS

Text: After 12 weeks of induction gemcitabine and capecitabine chemotherapy (three cycles of gemcitabine [1000 mg/m (2) on days 1, 8, 15 of a 28-day cycle] and capecitabine [830 mg/m (2) twice daily on days 1-21 of a 28-day cycle]), patients with stable or responding disease, tumour diameter of 6 cm or less, and WHO performance status 0-1 were randomly assigned to receive a further cycle of gemcitabine and capecitabine chemotherapy followed by either gemcitabine (300 mg/m (2) once per week) or capecitabine (830 mg/m (2) twice daily, Monday to Friday only), both in combination with radiation (504 Gy in 28 fractions).