Document Classification

Section Type: RESULTS

Text: The 201L allele of S201L [TT versus CC : odds ratio (OR), 1. 74 ; 95 % confidence interval (95 % CI), 1. 15-2. 62 ; TC versus CC : OR, 1. 17 ; 95 % CI, 0. 93-1. 49] and the 277E allele of K277E (GG versus AA : OR, 1. 66 ; 95 % CI, 1. 03-2. 68 ; GA versus AA : OR, 1. 21 ; 95 % CI, 0. 96-1. 53) were associated with increased risk of advanced distal colorectal adenoma (both P (trend) < / = 0. 02) ; the TGTGCG haplotype of six informative single nucleotide polymorphisms was also associated with increased risk (OR, 1. 27 ; 95 % CI, 1. 03-1. 55).