Document Classification

Section Type: METHODS

Text: Patients were stratified according to number of involved nodes and type of primary surgery and randomized to receive the following : (1) tamoxifen 10 mg twice daily by mouth for 1 year ; (2) cyclophosphamide 60 mg/m2/d by mouth for 1 year, methotrexate 15 mg/m2 intravenously (IV) weekly for 1 year, fluorouracil (5-FU) 400 mg/m2 IV weekly for 1 year, vincristine. 625 mg/m2 IV weekly for the first 10 weeks, and prednisone during weeks 1 to 10 with doses decreasing from 30 mg/m2 to 2. 5 mg/m2 (CMFVP) ; or (3) the combination of tamoxifen and CMFVP.