Document Classification

Section Type: RESULTS

Text: The C (max), AUC ((0-6)), AUC ((0-48)) and AUC ((0-infinity)) of ilaprazole were all significantly different across the 3 CYP3A5 genotypes (including 4 of CYP3A5 * 1 / * 1, 4 of * 1 / * 3, 3 of * 3 / * 3 ; P < 0. 05) in CYP2C19 wild-type subjects (CYP2C19 wt/wts), similar variety of C (max) and AUC ((0-6)) among CYP3A5 genotypes (including 3 of CYP3A5 * 1 / * 1, 3 of * 1 / * 3, 4 of * 3 / * 3 ; P < 0. 05) were also observed in CYP2C19 heterozygous subjects (CYP2C19 wt/mts).