Document Classification

Section Type: METHODS

Text: Four hundred forty-one women with axillary lymph node positive breast carcinoma were randomized to receive either combination chemotherapy with cyclophosphamide (60 mg/m (2) orally every day for 1 year), fluorouracil (300 mg/m (2) intravenously [IV] weekly for 1 year), methotrexate (15 mg/m (2) IV weekly for 1 year), vincristine (0. 625 mg/m (2) IV for 10 weeks), prednisone (30 mg/m (2) orally on Days 1-14, 20 mg/m (2) on Days 15-28, and 10 mg/m (2) on Days 29-42), or single-agent chemotherapy with L-PAM (5 mg/m (2) orally every day for 5 days every 6 weeks for 2 years) after undergoing surgery.