Document Classification

Section Type: RESULTS

Text: Compared with baseline, there was a greater reduction in malondialdehyde, nitrotyrosine, interleukin-6, and endothelin-1 and a greater increase in flow-mediated dilation, coronary flow reserve, aortic distensibility, systolic velocity of mitral annulus, and E/Em after anakinra than after placebo (malondialdehyde -25 % versus 9 % ; nitrotyrosine -38 % versus -11 % ; interleukin-6 -29 % versus 0. 9 % ; endothelin-1 -36 % versus -11 % ; flow-mediated dilation 45 % versus -9 % ; coronary flow reserve 29 % versus 4 % ; and aortic distensibility 45 % versus 2 % ; P < 0. 05 for all comparisons).