Document Classification

Section Type: METHODS

Text: In this randomized phase II trial, 80 patients were treated : arm A (IRINOX) in 40 patients received at day 1 oxaliplatin 85 mg/m (2) and irinotecan 180 mg/m (2) biweekly, standard arm B received a biweekly simplified folinic acid (FA) and fluorouracil (FU), FA 200 mg/m (2) in a 2-h infusion and bolus injection of 5FU 400 mg/m (2) on day 1, then a two 400 mg/m (2) continuous infusion of FU on days 1 and 2 with either oxaliplatin 85 mg/m (2) (20 patients) or irinotecan 180 mg/m (2) (20 patients).