Document Classification

Section Type: METHODS

Text: This open-label, parallel-group study randomized adults with end-stage renal disease undergoing primary kidney transplantation or retransplantation to an initial dose of tacrolimus BD 0. 2 mg/kg per day (Arm 1 ; n = 309), QD 0. 2 mg/kg per day (Arm 2 ; n = 302), QD 0. 3 mg/kg per day (Arm 3 ; n = 304) all with mycophenolate mofetil and corticosteroids (tapered) over 24 weeks, or tacrolimus QD 0. 2 mg/kg per day with mycophenolate mofetil, basiliximab, and corticosteroids given only perioperatively (Arm 4 ; n = 283).