Document Classification

Section Type: METHODS

Text: Circulating total and unconjugated isoflavone concentrations were determined by mass spectrometry in plasma samples from 7 separate studies : 1) in Sprague-Dawley rats and in 3 strains of mice fed commercial soy-containing diets ; 2) in Sprague-Dawley rats gavaged with genistein ; 3) in healthy adults who consumed single servings of soy nuts, soy milk, and tempeh ; 4) in healthy adults subchronically given soy milk ; 5) in healthy women orally administered 50 mg genistein ; 6) in healthy women orally administered 20 mg pure S - (-) equol ; and 7) in 6-mo-old infants fed soy infant formula and later, at age 3 y, a soy germ isoflavone supplement.