Document Classification

Section Type: RESULTS

Text: In the intention-to-treat group, vaccination also statistically significantly reduced the risk of any high-grade cervical lesions (19. 0 % reduction ; rate vaccine = 1. 43, rate placebo = 1. 76, difference = 0. 33, 95 % confidence interval [CI] = 0. 13 to 0. 54), vulvar and vaginal lesions (50. 7 % reduction ; rate vaccine = 0. 10, rate placebo = 0. 20, difference = 0. 10, 95 % CI = 0. 04 to 0. 16), genital warts (62. 0 % reduction ; rate vaccine = 0. 44, rate placebo = 1. 17, difference = 0. 72, 95 % CI = 0. 58 to 0. 87), Pap abnormalities (11. 3 % reduction ; rate vaccine = 10. 36, rate placebo = 11. 68, difference = 1. 32, 95 % CI = 0. 74 to 1. 90), and cervical definitive therapy (23. 0 % reduction ; rate vaccine = 1. 97, rate placebo = 2. 56, difference = 0. 59, 95 % CI = 0. 35 to 0. 83), irrespective of causal HPV type.