Document Classification

Section Type: RESULTS

Text: Pyridostigmine reduced cholinesterase activity by 30 %, inhibited the chronotropic response throughout exercise, up to 60 % of maximal effort (pyridostigmine = 108 + / - 3 beats/min vs. placebo = 113 + / - 3 beats/min ; P =. 040), and improved heart rate reserve (pyridostigmine = 73 + / - 5 beats/min vs. placebo = 69 + / - 5 beats/min ; P = 0. 035) and heart rate recovery in the first minute after exercise (pyridostigmine = 25 + / - 2 beats/min vs. placebo = 22 + / - 2 beats/min ; P =. 005), whereas peak heart rate was similar to placebo.