Document Classification

Section Type: RESULTS

Text: Haematological and non-haematological toxic effects that were significantly more common in the carboplatin group than in the no-carboplatin group included grade 3 or 4 neutropenia (192 [65 %] vs 79 [27 %]), grade 3 or 4 anaemia (45 [15 %] vs one [< 1 %]), grade 3 or 4 thrombocytopenia (42 [14 %] vs one [< 1 %]), and grade 3 or 4 diarrhoea (51 [17 %] vs 32 [11 %]) ; carboplatin was more often associated with dose discontinuations (141 [48 %] with carboplatin and 114 [39 %] without carboplatin ; p = 0031).