Document Classification

Section Type: RESULTS

Text: After 20 days of treatment, plasma corticotropin and cortisol concentrations were similar before challenge, but ipsapirone IR-induced increases in plasma corticotropin and cortisol concentrations were significantly lower in both the ipsapirone CR group (corticotropin, 6. 5 + / - 2 pg/ml ; cortisol, 1. 5 + / - 0. 7 micrograms/dl) and fluoxetine group (corticotropin 4. 4 + / - 2 pg/ml ; cortisol 1. 5 + / - 0. 7 micrograms/dl) compared with placebo (corticotropin, 34 + / - 14 pg/ml ; cortisol, 5. 8 + / - 2 micrograms/dl, mean + / - SEM).