Document Classification

Section Type: RESULTS

Text: At 12 months, patients on carvedilol, compared with those continuing on metoprolol, showed a decrease in LV dimensions (end-diastolic volume -8 + / -7 vs. +7 + / -6 ml/m2, p = 0. 053 ; end-systolic volume -7 + / -5 vs. +6 + / -4 ml/m2, p = 0. 047), an improvement in LV ejection fraction (+7 + / -3 % vs. -1 + / -2 %, p = 0. 045), a reduction in ventricular ectopic beats (-12 + / -9 vs. +62 + / -50 n/h, p = 0. 05) and couplets (-0. 5 + / -0. 4 vs. +1. 5 + / -0. 6 n/h, p = 0. 048), no significant benefit on symptoms and quality of life and a negative effect on peak oxygen consumption (-0. 6 + / -0. 6 vs. +1. 3 + / -0. 5 ml/kg/min, p = 0. 03).