Document Classification

Section Type: METHODS

Text: In an open, controlled, randomized, parallel-group, single-centre, 16-week pilot study, 52 patients (age 65. 6 + / -9. 2 years ; diabetes duration 15. 3 + / -7. 6 years ; insulin therapy duration 4. 2 + / -1. 7 years, body mass index 31. 4 + / -2. 9 kg/m2) with Type 2 diabetes (HbA1c > or = 8. 0 %) on premixed human insulin (75/25 or 70/30) were randomized to once-daily morning insulin glargine plus glimepiride (Group A ; n = 17), insulin glargine plus glimepiride and metformin (Group B ; n = 18) or premixed insulin (Group C ; n = 17).