Document Classification

Section Type: RESULTS

Text: The mean values for C (max), T (max), AUC, and AUC ()) with the test formulation of rifampicin were 7. 20 g/mL, 1. 32 hours, 37. 12 g/mL h, and 39. 69 g/mL h, respectively ; for the reference formulation, the values were 7. 65 g/mL, 1. 71 hours, 38. 92 g/mL h, and 42. 24 g / mL h. For 25-desacetyl rifampicin, the mean values for C (max), T (max), AUC, and AUC ()) with the test formulation were 0. 63 g/mL, 3. 45 hours, 4. 92 g/mL h, and 6. 27 g/mL h ; for the reference formulation, the values were 0. 7 g/mL, 3. 27 hours, 5. 23 g/mL h, and 6. 84 g/mL h. For rifampicin, the 90 % CIs for the test formulation/reference formulation ratio for the logarithmic transformations of both C (max) and AUC ()) were within the bioequivalence limit of 80 % to 125 % (80. 9109. 7 and 80. 7-103. 2, respectively).