Document Classification

Section Type: RESULTS

Text: After 12 months of follow-up, allocation to 20 mg of simvastatin daily reduced nonfasting total cholesterol levels by 18 % (simvastatin, 163 mg/dL [4. 22 mmol/L] versus placebo, 196 mg/dL [5. 08 mmol/L] ; P < 0. 0001), directly measured low-density lipoprotein cholesterol levels by 24 % (89 mg/dL [2. 31 mmol/L] versus 114 mg/dL [2. 96 mmol/L] ; P < 0. 0001), and triglyceride levels by 13 % (166 mg/dL [1. 87 mmol/L] versus 186 mg/dL [2. 10 mmol/L] ; P < 0. 01), but there was no significant effect on high-density lipoprotein cholesterol levels (2 % increase ; P = NS).