Document Classification

Section Type: RESULTS

Text: The concurrent administration of both drugs resulted in a 12 % greater Cmax (9. 5 ng ml (-1) versus 8. 4 ng ml (-1) ; P = 0. 01) and a 12 % greater AUC (0-24) (135. 2 ng h ml (-1) versus 118. 7 ng h ml (-1) ; P = 0. 001) than donepezil alone on day 1, and a 26. 8 % greater Cmax (37. 7 ng ml (-1) versus 27. 6 ng ml (-1) ; P < 0. 0001) and a 26. 4 % greater AUC (0-24) (680. 9 ng h ml (-1) versus 501. 0 ng h ml (-1) ; P < 0. 0001) than donepezil alone on day 7.