Document Classification

Section Type: RESULTS

Text: Lasofoxifene at a dose of 0. 5 mg per day, as compared with placebo, was associated with reduced risks of vertebral fracture (13. 1 cases vs. 22. 4 cases per 1000 person-years ; hazard ratio, 0. 58 ; 95 % confidence interval [CI], 0. 47 to 0. 70), nonvertebral fracture (18. 7 vs. 24. 5 cases per 1000 person-years ; hazard ratio, 0. 76 ; 95 % CI, 0. 64 to 0. 91), ER-positive breast cancer (0. 3 vs. 1. 7 cases per 1000 person-years ; hazard ratio, 0. 19 ; 95 % CI, 0. 07 to 0. 56), coronary heart disease events (5. 1 vs. 7. 5 cases per 1000 person-years ; hazard ratio, 0. 68 ; 95 % CI, 0. 50 to 0. 93), and stroke (2. 5 vs. 3. 9 cases per 1000 person-years ; hazard ratio, 0. 64 ; 95 % CI, 0. 41 to 0. 99).