Document Classification

Section Type: RESULTS

Text: The maximum, area under the curve and trough values of receptor occupancy significantly differed between the ARBs [geometric mean (and 95 % CI) of trough value 18. 1 (12. 9, 25. 3) for irbesartan, 9. 6 (6. 0, 15. 3) for valsartan and 5. 5 (2. 8, 10. 8) for candesartan, respectively] and were negatively correlated with the change in urinary 8-isoprostane (r = -0. 46 - -0. 55, P < 0. 05), but not the markers of insulin resistance (r = 0. 02-0. 15, P = 0. 46-0. 94).