Document Classification

Section Type: RESULTS

Text: Insulin sensitizers significantly improved metabolic parameters (homeostasis model assessment-insulin resistance score, P < 0. 05), serum aminotransferase levels [aspartate aminotransferase (AST) : 45. 9 + / - 24. 2 to 33. 3 + / - 17. 7 IU/L, P < 0. 01 ; alanine aminotransferase (ALT) : 78. 2 + / - 46. 3 to 47. 3 + / - 34. 5 IU/L, P < 0. 001] and histological features (median non-alcoholic fatty liver disease activity score : 5. 0-3. 0, P = 0. 01), while diet and exercise improved serum aminotransferase levels (AST : 39. 3 + / - 11. 1 to 30. 0 + / - 8. 6 IU/L, P < 0. 01 ; ALT : 66. 9 + / - 28. 9 to 42. 0 + / - 16. 2 IU/L, P < 0. 001) at the end of the 48 weeks when compared to baseline.