Document Classification

Section Type: RESULTS

Text: Median PFS and OS times were 7. 3 months (95 % CI, 5. 3 to 8. 8 months) and 23. 8 months (95 % CI, 16. 2 months to not reached), respectively, in arm A and 6. 1 months (95 % CI, 3. 7 to 8. 6 months) and 16. 9 months (95 % CI, 12. 8 to 25. 8 months), respectively, in arm B. Baseline factors associated with improved OS on exploratory multivariate analysis were an Eastern Cooperative Oncology Group performance status of 0 (hazard ratio [HR], 0. 27 ; 95 % CI, 0. 14 to 0. 51), presence of bone or lymph node metastases only (HR, 0. 45 ; 95 % CI, 0. 25 to 0. 79), and treatment assignment to OGX-011 (HR, 0. 50 ; 95 % CI, 0. 29 to 0. 87).