Document Classification

Section Type: RESULTS

Text: In arms 1-3, the median estimated area under the curves (AUC) (0-24) for the statins were : pravastatin (arm 1, n = 13), 151 and 75 ng. h / ml on days 4 and 18 (decline of 50 % in presence of RTV/SQVsgc), respectively (P = 0. 005) ; simvastatin (arm 2, n = 14), 17 and 548 ng. h / ml on days 4 and 18 (increase of 3059 % in the presence of RTV/SQVsgc), respectively (P < 0. 001) ; and total active atorvastatin (arm 3, n = 14), 167 and 289 ng. h / ml on days 4 and 18 (increase of 79 % in the presence of RTV/SQVsgc), respectively (P < 0. 001).