Document Classification

Section Type: RESULTS

Text: Plasma concentration-time curves and geometric means for pharmacokinetic parameters were similar for the cold chain vs. original patch in SP951 (AUC (0-tz) : 2. 68 vs. 2. 71 ng/mL * h ; point estimate : 0. 99 [90 % confidence interval (CI) : 0. 91, 1. 07]) (Cmax : 0. 131 vs. 0. 136 ng/mL ; 0. 96 [0. 89, 1. 04]) and for the room temperature stable vs. cold chain patch in SP0987 (AUC (0-tz) : 4. 51 vs. 4. 87 ng/mL * h ; 0. 90 [0. 84, 0. 97]) (Cmax : 0. 23 vs. 0. 23 ng/mL ; 0. 95 [0. 88, 1. 02]).