Document Classification

Section Type: RESULTS

Text: Two chromosomal abnormalities were associated with a significantly better outcome (ETV6-RUNX1, hazard ratio [HR] 0. 51, 95 % CI 0. 38-0. 70 and high hyperdiploidy, 0. 60, 0. 47-0. 78), whereas five abnormalities were associated with an increased risk of relapse (intrachromosomal amplification of chromosome 21 [iAMP21], 6. 04, 3. 90-9. 35 ; t (9 ; 22), 3. 55, 2. 21-5. 72 ; MLL translocations, 2. 98, 1. 71-5. 20 ; abnormal 17p, 2. 09, 1. 30-3. 37 ; and loss of 13q, 1. 87, 1. 09-3. 20).