Document Classification

Section Type: RESULTS

Text: There were significant increases in the concentrations of the formation markers PINP (P = 0. 045) and OC (1-49) (P = 0. 006) and in the PINP : CTX-I ratio (P = 0. 015), and a more positive bone remodelling balance index (P = 0. 03) was observed in patients on the lowest dose C than in those on the highest dose A. Mean 24-h cortisol concentrations correlated negatively with CTX-I (r = -0. 66 and P = 0. 04) and TRACP5b (r = -0. 74 and P = 0. 01) in patients on dose B and with OC (1-49) (r = -0. 66 and P = 0. 04) and CTX-I (r = -0. 81 and P < 0. 01) in patients on dose C.