Document Classification

Section Type: RESULTS

Text: Toxicities included acute cholinergic syndrome (group A 53 %, group B 19 % ; P < 0. 0001), late-onset diarrhea grade 1/2 (group A 21 %, group B 46 %) and grade 3/4 (group A 41 %, group B 66 % ; P < 0. 0001), nausea and vomiting grade 1/2 (group A 34 %, group B 59 %) and grade 3/4 (group A 30 %, group B 12 % ; P < 0. 0001), neutropenia grade 3/4 (group A 27 %, group B 28 % ; P < 0. 03), with febrile neutropenia seen in only four patients in group A, anemia grade more than 2 (group A 28 %, group B 12 % ; P < 0. 05), asthenia grade more than 3 (group A 24 %, group B 18 % ; P < 0. 001), and alopecia grade more than 3 (group A 40 %, group B 34 % ; P < 0. 2).