Document Classification

Section Type: RESULTS

Text: After a similar early asthmatic response (mean Deltaforced expiratory volume in 1 s (FEV1), max -29. 4 (SD 7. 2) vs. -33. 1 (8. 6) % ; mean difference 3. 6 (95 % CI -0. 9 to 8. 2) %), the late asthmatic response (mean DeltaFEV1, max -45. 9 (21. 9) vs. -32. 7 (22. 3) % ; mean difference 13. 2 (3. 8-22. 3) %), the degree of allergen-induced bronchial hyper-responsiveness (mean DeltaPC20histamine, 1. 8 (1. 0) vs. 1. 2 (0. 9) doubling dose ; mean difference 0. 6 (0. 2-1. 1) doubling dose) and serum IL-5 at 6 h were found to be significantly higher after bronchial challenge with HDM extract than after challenge with an isolated HDM major allergen.