Document Classification

Section Type: RESULTS

Text: After administration of multiple doses, the cefotetan disodium C (max, ss) was 80. 53 (10. 04) mg/L ; the C (mix, ss) was 11. 00 (4. 04) mg/L ; the AUC (ss) was 347. 92 (50. 04) mg h/L ; the steady-state plasma concentration was 28. 99 (4. 17) mg/L ; the t (1/2) was 6. 24 (2. 52) hours ; the CL was 2. 32 (0. 64) L/h ; and the Vd was 19. 19 (4. 58) L. No significant differences in pharmacokinetic parameters were noted by sex in the multiple-dose phase.