Document Classification

Section Type: RESULTS

Text: Increases in IgG binding to insulin, saliva IgA binding to insulin, or CD4 + T-cell proliferative responses to insulin were observed in 2 of 10 (20 % [95 % CI, 0. 1 % -45 %]) placebo-treated children and in 1 of 6 (16. 7 % [95 % CI, 0. 1 % -46 %]) children treated with 2. 5 mg of insulin, 1 of 6 (16. 7 % [95 % CI, 0. 1 % -46 %]) treated with 7. 5 mg, 2 of 6 (33. 3 % [95 % CI, 0. 1 % -71 %]) treated with 22. 5 mg, and 5 of 6 (83. 3 % [95 % CI, 53 % -99. 9 %]) treated with 67. 5 mg (P =. 02).