Document Classification

Section Type: METHODS

Text: Patients with tumors 40 mm, or < 40 mm and N1-3M0 were randomly assigned to one of four treatment arms : (A) two ICT cycles (fluorouracil 800 mg/m (2) / d intravenous [IV] infusion, days 1 through 4 and 29 to 32 ; and cisplatin 80 mg/m (2) IV, on days 1 and 29), RCT (45 Gy in 25 fractions over 5 weeks, fluorouracil and cisplatin during weeks 1 and 5), and standard-dose boost (SD ; 15 Gy) ; (B) two ICT cycles, RCT, and high-dose boost (HD ; 20-25 Gy) ; (C) : RCT and SD boost (reference arm) ; and (D) RCT and HD boost.