Document Classification

Section Type: RESULTS

Text: Thioridazine, 50 mg, reduced standing systolic blood pressure (mean peak changes from baseline [95 % CI] -32 mm Hg [-55, 10 mm Hg] ; p < 0. 01 versus placebo) and diastolic blood pressure (-14 mm Hg [-26, -2 mm Hg] ; p < 0. 05), increased standing heart rate (7 beats/min [-1, 16 beats/min] ; p < 0. 05), impaired psychomotor function, and prolonged the JT (20 ms1/2 [7, 34 ms1/2] ; p < 0. 05), QTa (22 ms1/2 [8, 36 ms1/2] ; p < 0. 05), and QTc (22 ms1/2 [11, 33 ms1/2] ; p < 0. 01) intervals, but had no effect on QT dispersion (-12 ms1/2 [-31, 6 ms1/2]).