Document Classification

Section Type: RESULTS

Text: The level of inflammation and oxidative stress was markedly reduced in the SDAT patients treated with the test formulation when compared to the donepezil-treated group indicating a likely mechanism of action of the test formulation (homocysteine 30. 22 3. 87 vs 44. 73 7. 11 nmol/L, P < 0. 0001 ; C-reactive protein [CRP] 4. 751 1. 149 vs 5. 887 1. 049 mg/L, P < 0. 0001 ; tumour necrosis factor alpha [TNF -] 1139. 45 198. 87 vs 1598. 77 298. 52 pg/ml, P < 0. 0001 ; superoxide dismutase [SOD] 1145. 92 228. 75 vs 1296 225. 72 U/g Hb, P = 0. 0013 ; glutathione peroxidase [GPx] 20. 78 3. 14 vs 25. 99 4. 11 U/g Hb, P < 0. 0001 ; glutathione [GSH] 9. 358 2. 139 vs 6. 831 1. 139 U/g Hb, P < 0. 0001 ; thiobarbituric acid reactive substances [TBARS] 131. 62 29. 68 vs 176. 40 68. 11 nmol/g Hb, P < 0. 0001).