Document Classification

Section Type: RESULTS

Text: After intravenous administration of single doses of 0. 5, 1. 0, and 2. 0 g, the cefotetan disodium C (max) was 35. 01 (6. 98), 76. 67 (10. 52), and 154. 33 (27. 17) mg/L, respectively ; the AUC (h) was 145. 35 (18. 36), 307. 45 (33. 07), and 746. 09 (103. 07) mg h/L ; the AUC () was 171. 51 (20. 61), 347. 25 (44. 20), and 843. 84 (131. 13) mg h/L ; the t (1/2) was 5. 80 (1. 29), 4. 91 (1. 15), and 5. 04 (1. 26) hours ; the CL was 2. 96 (0. 41), 2. 92 (0. 39), and 2. 42 (0. 39) L/h ; and the V (d) was 24. 55 (5. 19), 20. 37 (3. 66), and 17. 30 (3. 52) L.