Document Classification

Section Type: METHODS

Text: One hundred and twenty healthy consenting patients undergoing major plastic surgery (e. g., breast augmentation, abdominoplasty procedures) using a standardized general anesthetic technique were randomized to one of three treatment groups : 1) control group (n = 40) received two placebos orally before and after surgery, as well as one placebo BID for 3 days after surgery ; 2) postoperative group (n = 40) received two placebos before surgery and 2 celecoxib 200 mg p. o. after surgery, followed by one celecoxib 200 mg p. o. BID on postoperative day # 1, # 2 and # 3 ; and 3) perioperative group (n = 40) received 2 celecoxib 200 mg p. o. 30-90 min before surgery, and two placebos after surgery, followed by one celecoxib 200 mg p. o. BID on postoperative day # 1, # 2, and # 3.