Document Classification

Section Type: RESULTS

Text: Safety parameters statistically significantly related to dose were mean weight change (low : +0. 67 [SD = 4. 38], medium : +0. 89 [SD = 3. 87], high : +1. 70 [SD = 4. 14] kg, p =. 024 ; effect size [ES] = 0. 264 high vs. low dose), mean change in prolactin (low : -5. 61 [SD = 12. 49], medium : -2. 76 [SD = 19. 02]), high : +3. 58 [SD = 33. 78] g/L, p =. 001 ; ES = 0. 410 high vs. low dose), fasting triglycerides change from normal at baseline to high (low : 3. 2 %, medium : 6. 0 %, high : 18. 9 %, p =. 001 ; NNT = 7 high vs. low dose) and fasting high-density lipoprotein cholesterol change from normal at baseline to low (low : 13. 8 %, medium : 19. 6 %, high : 30. 7 %, p =. 019 ; NNT = 6 high vs. low dose).