Document Classification

Section Type: METHODS

Text: Patients received one of three treatments : (A) intensive-course 5-FU plus l-leucovorin with I. V. leucovorin (Immunex Corp, Seattle, WA) at 100 mg/m2 and I. V. 5-FU at 370 mg/m2 ; (B) intensive-course 5-FU plus oral (d, l) - leucovorin with oral leucovarin at 125 mg/m2 on hours 0, 1, 2, and 3 (total dose, 500 mg/m2) followed by 5-FU 370 mg/m2 on hour 4 ; or (C) intensive-course 5-FU plus I. V. (d, l) - leucovorin with I. V. leucovorin 200 mg/m2 and 5-FU 370 mg/m2.