Document Classification

Section Type: RESULTS

Text: After 3 and 7 weeks of treatment with 5-methyltetrahydrofolate, homocysteine levels fell from 11. 6 + / - 1. 5 to 9. 0 + / - 2. 3 and 8. 7 + / - 1. 8 (P < 0. 005) in wild-type subjects and from 16. 9 + / - 6. 8 to 12. 3 + / - 4. 3 and 11. 6 + / - 4. 4 mumol/L, mean + / - SD (P < 0. 005) in homozygous subjects, proving biological availability of 5-methyltetrahydrofolate irrespective of the 677C -- > T genotype.