Document Classification

Section Type: RESULTS

Text: Averaged over the course of double-blind treatment, topiramate, compared with placebo, improved the odds of overall well-being (odds ratio [OR] = 2. 17 ; 95 % confidence interval [CI], 1. 16-2. 60 ; P =. 01) ; reported abstinence and not seeking alcohol (OR = 2. 63 ; 95 % CI, 1. 52-4. 53 ; P =. 001) ; overall life satisfaction (OR = 2. 28 ; 95 % CI, 1. 21-4. 29 ; P =. 01) ; and reduced harmful drinking consequences (OR = -0. 07 ; 95 % CI, -0. 12 to -0. 02, P =. 01).