Document Classification

Section Type: METHODS

Text: Seventy-five patients undergoing major abdominal surgery were randomly assigned to receive (1) intraoperative remifentanil at 0. 05 microg x kg (-1) x min (-1) (small-dose remifentanil) ; (2) intraoperative remifentanil at 0. 40 microg x kg (-1) x min (-1) (large-dose remifentanil) ; or (3) intraoperative remifentanil at 0. 40 microg x kg (-1) x min (-1) and 0. 5 mg/kg ketamine just after the induction, followed by an intraoperative infusion of 5 microg x kg (-1) x min (-1) until skin closure and then 2 microg x kg (-1) x min (-1) for 48 h (large-dose remifentanil-ketamine).