Document Classification

Section Type: RESULTS

Text: The pharmacokinetic parameters of PMEA following ADV 10, 20 and 40 mg were : geometric mean [95 % confidence interval (CI)] for AUC (0-24 h) 227 (205, 253), 423 (361, 506) and 686 (585, 828) microg l (-1) h, C (max) 23. 0 (20. 7, 27. 3), 47. 4 (42. 8, 53. 2) and 83. 6 (72. 6, 97. 4) microg l (-1), arithmetic mean (95 % CI) for t (1/2) 6. 8 (6. 3, 7. 3), 7. 4 (6. 7, 8. 1) and 7. 7 (6. 5, 8. 9) h, median value (range) for t (max) 1. 00 (1. 00-2. 00), 0. 75 (0. 75-2. 50) and 1. 00 (0. 75-2. 00) h, respectively.