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It is possible to standardize single nucleotide polymorphism array analysis in acute myeloid leukemia/myelodysplastic syndromes and compare the results with the abnormalities detected by karyotyping.
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Many algorithms have been used to analyze medical hyperspectral image data, each having their own strengths and short-comings.
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This study aimed to study the aesthetic effect of autologous fat transplantation in frontotemporal depression filling as well as the influence on the Symptom Checklist 90 (SCL-90) and the Rosenberg Self-Esteem Scale (SES) score of patients.
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The spherical or multilayered spherical structures of liposomes are highly rich in lipid contents with numerous criteria for their classification, including structural features, structural parameters, and size, synthesis methods, preparation, and drug loading.
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We performed northern blotting, in situ hybridization, immunohistochemistry, and RT-PCR.
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63 patients in the IM group and 71 patients in the UM group reached clear diagnosis (90.0% vs. 91.0%, p = 0.831).
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We also showed that the two FBXW7 substrates, NOTCH1 and myeloid cell leukemia sequence 1 (MCL1), regulate cholangiocarcinoma progression.
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This unusual combination has not been reported previously, although each entity has been described separately in tuberous sclerosis.
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Of the 70 benign tumors, 51 (72.9%) were greater than 8 cm in diameter and 55 (78.6%) were preoperatively diagnosed before the 10th gestational week; 44 (62.9%) were operated before the 15th gestational week.
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Considering the effect of hormone therapy and fertility factors on breast cancer and changeability of listed risk factors, the researchers suggest planning for sensitizing, increasing the awareness, and educating women and professionals regarding the influence of fertility and hormonal factors including pregnancy at lower ages, minimizing the use of hormones for contraception, and hormone therapy.
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The proposed total inverse planning paradigm using a 3D-printed immobilization device is feasible and renders comparable inter-fraction performance while offering a better patient experience, potentially improving cnsRT workflows and its cost-effectiveness.
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The patient did not respond well to chemotherapy and died three months after the diagnosis.
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Yet, each type is distinct, possessed of defining morphologic, histologic, biochemical, and genomic features that have allowed oncologists to develop a nosology that guides diagnosis and therapy.
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These recommended guidelines are not mandated but rather exist to help clinicians and veterinary pathologists optimally handle neoplastic biopsy samples.
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Patients with low Karnofsky Performance Status, high Mini Mental State-score, hospitalized, recently diagnosed or undergoing opioid titration were at increased risk of symptom underestimation by providers (all p < 0.001).
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In the SKBR3 cell line, a statistically significant decrease of the expression level of phosphorylated (p-)AKT, p-ribosomal protein S6 kinase B1, p-extracellular signal regulated kinase 1/2 and p-mitogen-activated protein kinase kinase 1 was observed after exposure to trastuzumab.
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Nowadays, several long noncoding RNAs (lncRNAs) have been reported as molecular alterations involved in SLE.
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Cell migration and invasion ability were examined by wound healing and transwell assays.
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As a result, G0/G1 cycle arrest was observed in MCF-7 cells and no cell cycle arrest at all was observed in MDA-MB-231 cells.
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AC tended to have a worse prognosis than TC (p = 0.08).
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Transurethral biopsy of the lesion was performed and pathological examination revealed a muscle-invasive adenocarcinoma.
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The protein expression levels of cyclin D1, bcl-2, bax, caspase 3, caspase 9, autophagy-related gene 7, microtubule-associated protein 1 light chain 3-I (LC3-I), LC3-II, Beclin 1, p62, mitogen-activated protein kinase (MAPK), extracellular regulated protein kinases (ERK), and phosphatidylinositol 3 kinase (PI3K) in SNU-216 cells were detected using western blotting.
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In the serum of rats with renal I/R injury and prolonged reperfusion time, the contents of Cr and BUN were increased, the positive expression of SHP-2 was higher, the level of apoptosis was promoted, IL-6, TNF-α, IL-1β and SHP27 expression in the serum was increased, the expression of SHP2, TLR4, NF-κB, IL-6, TNF-α and Bax was up-regulated, and the expression of Bcl-2 was down-regulated.
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Malignant melanoma in blacks represents a small, well-delineated subset of melanomas possibly with its own incidence and prognosis.
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To develop students' intercultural communication skills is the goal of intercultural education.
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In addition, the PKM2-shRNA group exhibited significantly increased apoptosis rates and β-galactosidase activity compared with the blank and empty plasmid groups.
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ELM and histologic diagnoses were then compared to assess the sensitivity, specificity, and diagnostic accuracy as well as positive and negative predictive values (PPV and NPV, respectively) for TMs of the 3 algorithmic methods.
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Literature searches were performed in PubMed, Scopus, the Educational Resources Information Center (ERIC), the Cumulative Index to Nursing and Allied Health Literature (EBSCO), and Dissertation Abstracts-ProQuest.
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Recent advances in the field of MCL are reviewed.
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Twenty were T1 (69%) and 9 were T2 (31%).
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The ORR of 29 patients receiving more than three cycles of treatment was higher than that of those receiving less than three cycles of treatment (31.03% vs 0%, P=0.038), and there was a significant difference in PFS (7.6 vs 4.9 months, P=0.004) and OS (11.7 vs 8.9 months, P=0.002).
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Adriamycin (ADR) is an anti-cancer drug which offers improvement in survival for acute myeloid leukemia (AML) patients.
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miR-522-3p is known to degrade bloom syndrome protein (BLM) and enhance expression of other proto-oncogenes, leading to tumorigenesis.
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The role of cytology in 44 cases of renal adenocarcinoma was evaluated.
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Records for all patients who underwent open thoracotomy for curative resection of primary lung cancer between 2009 and 2013 in a tertiary care hospital were retrospectively analyzed.
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The objective of the present study was to explore treatment options and long-term outcomes in patients with metastatic chordoma.
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Hydrazone 29 has been selected by the Biological Evaluation Committee of NCI for testing in vivo Hollow Fiber Assay.
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Further research is needed to better understand how to intervene on both area and individual social determinants of health and develop interventions to address these disparities.
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Models that predict survival and recurrence in patients with early-stage cervical cancer are important tools in patient management.
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Carrier-immobilized carbohydrate structures enable the histochemical investigation of the protein part of this recognitive system.
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The interneural tissue was excised separately after a routine axillary dissection.
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Altogether, LCZ676 could potentially alleviate cardiac remodeling in mice with PAH via blockade of the ERK signaling pathway activation.
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Macrophage-mediated cytostasis was measured in a mouse syngeneic system where EL4 thymoma cells were found to be inhibited by C57B1/6 mouse macrophages.
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Furthermore, our in vivo results showed that overexpression of miR-145 or silencing of lncRNA PVT1 resulted in decreased tumor growth in nude mice.
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CECs were isolated from peripheral blood, captured with ferrofluids coated with monoclonal antibodies directed against the CD146 antigen, and assessed centrally with an automated standardized system.
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Patient enrollment started on January 1, 2014, and closed on March 31, 2016, with 54 patients.
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By applying chemogenetic techniques, we enhanced and inhibited neuronal activity in vitro and in a mouse model to study how neuronal activity regulates microglial polarization and affects GBM progression.
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After treatment with 5-FU, MTX and VP-16 regimen, 21 of 26 gained complete respond (80.8%).
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Multispectroscopic evidence has shown interactions between these complexes and human serum albumin (HSA).
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Area under the curve (AUC) of each parameter and prebiopsy nomogram was assessed.
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In the current study, we investigated the methylation status in blood samples of 32 healthy donors and 60 lung cancer patients before and after treatment with neoadjuvant chemotherapy followed by total tumor resection.
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The compound had strong effect on the cells (IC50 = 0.55 μg/mL) by the suppression of HeLa cells proliferation in G2/M phase of cell cycle and induction of cell death through double-stranded DNA damage and reactive oxygen species overproduction.
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In benign liver tumours dermatan sulfate, in PHC and renal cell carcinoma chondroitin sulfate, but in Wilms' tumour hyaluronate was the prominent GAG subclass.
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Examples from the literature in which each type of bias occurs are presented, along with ways to mitigate these biases.
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We found that the BRD4 inhibitor JQ1 augments the antitumor efficacy of the CDK4/6 inhibitor abemaciclib (ABE).
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Incidence and mortality rate per population of 100,000.
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The study aims were to (a) test reliability of the Arabic versions of the Cancer Behavior Inventory-Brief Arabic (CBI-BA) among patients diagnosed with any type of cancer and the Functional Assessment of Cancer Therapy-Breast (FACT-BA) in women with breast cancer and (b) assess participant understanding of CBI-BA items.
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Our data support the general hypothesis of an association of Ewing's sarcoma family of tumors with farming, particularly at younger ages.
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The selected pharmacophore model Hypo 2 was used as a query model for further screening of 11,145 compounds from the PubChem, sc-PDB structure database, and designed novel ligands.
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The highest dose of MOTS-c that did not affect BMSCs proliferation was determined by CCK-8 assay.
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Ten prostate glands were examined.
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Patients were followed for treatment response and toxicity.
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Overall survival (OAS), radicality, extent of resection, recurrence, and morbidity were analyzed (log-rank test of survival, multivariate analysis).
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Adjuvant COSC has provided marginal benefits for HCC patients following curative HR.
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In this study, we identify whether miR-329 serves as a candidate regulator in melanoma.
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The first one was interpreted as accompanying the progressive loss of function of thyroid tumors, and was represented by the modifications of highly specialized structures such as RER, lysosomal dense bodies, colloid, etc.
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Notably, subgroup analyses showed that serum miR-376a, miR-376b and miR-376c levels had more significant prognostic values in patients with high grade gliomas than those with low grade gliomas.
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The present study aimed to investigate the biological function of miR-326 in PD through the JNK signaling pathway by targeting X-box binding protein 1 (XBP1).
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PFS and CSS from date of surgery.
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Besides, the underlying mechanism of OR3A4 in CRC development was explored through Western blot and RT-qPCR.
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At last, we explored the functions of miR-106a in HCC cells in vitro.
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Similarly, in combined group, the average number of SLNs per patient was 3.0, much higher than that of MB group, which was 2.1 (P < .05).
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We discuss the characteristics of a radial scar and its relationship to breast cancer based on our experience and a review of the literature.
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Median rating of the quality of websites was 50 of 100, with only 7 (17%) of centers receiving a composite score 80 (excellent) or better.
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Furthermore, the transwell assay showed that the invasion of the HepG2 cells decreased by 65% upon HHIP overexpression.
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The article first analyzed the limitation of international environmental law on China's environmental productivity, and then on this basis, the article conducted a numerical simulation of China's industrial and agricultural environmental productivity.
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In 6 of 20 WHO Grade 2 SCCs, TRAIL expression was slightly to moderately detected.
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According to relevant data, the detection rate of occupational stress among nurses was 100%, and the proportion of nurses who perceived considerable stress was 60.9%, which seriously affected their work efficiency and quality of life.
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The protein expression of S1PR1 was negatively regulated by miR‑148a in SKOV3 cells.
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Our aim was to randomly compare G-FOBT with I-FOBT in a screening population.
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The properties of a nonviable, aqueous ether-extracted Brucela abortus preparation, Bru-Pel, are described.
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Seventy percent contains fields of typical PNET alone or in combinations with mesenchymal and/r epithelial elements.
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It was, therefore, hypothesized that tetradecylthioacetic acid may inhibit the human MCF-7 cell growth by increasing the level of oxidative stress within the cell.
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This study sought to confirm latent classes of oncology patients and FCs with distinct depressive symptom trajectories and to examine differences in phenotypic and genotypic characteristics among these classes.
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Histological examination and TUNEL analyses of xenografts showed that cetuximab enhanced cell apoptosis induced by AdTRAIL.
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Their anti-proliferation effects against five human cancer cell lines including A549, MCF7, HepG2, HeLa, and PC-3 were evaluated by CCK-8 andlactate dehydrogenase (LDH) assay.
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CCAT2 was an endogenous sponge by competing for miR-216b, and miR-216b suppression alleviated CCAT2 silence-diminished cell growth and metastasis.
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Physician compensation has improved >20%.
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In this study, we aimed to explore the role of gamma ray treatment and its correlation with BTG2 in cell proliferation, apoptosis, and cell cycle arrest regulation in a lung cancer cell line.
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LMP1 functions as a carcinogen in lymphoma and nasopharyngeal carcinoma, and LMP1 may also promote gastric cancer.
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Inverse associations with ultraviolet radiation exposure and alcohol and fish intake, and positive associations with meat and saturated fat intake have been reported in several studies; additional studies are needed to confirm or refute these associations.
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In in vitro experiments, the percentage of cells exhibiting ALDH1 enzymatic activity significantly increased among cisplatin-surviving cells (CiSCs) according to flow cytometry.
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Radiation guidelines were not followed.
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After discussing the risks and morbidity of continuing treatment, he resumed chemoradiotherapy with an additional radiation dose of 45 Gy in 25 fractions.
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The objective in our study was to examine baseline and other characteristics associated with survival in patients with malignant pleural mesothelioma in Japan.
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In total, 60 patients survived more than 5 years.
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We conducted a rapid review of literature following PRISMA guidelines between January 2020 to August 2021 using (1) MEDLINE, (2) Embase, (3) CINAHL, and (4) PsychINFO and keyword searches for "cancer" and "COVID-19" focused on adults 65 years or older.
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In the course of the research on environmental productivity development, the article found a strong correlation between environmental productivity and international environmental law in China.
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However, a significant association of mTOR expression with BCR was found for specimens from the malignant border of the tumor (B) but not the tumor center (A) (p = 0.0034 log rank).
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This high density chemoresistance was observed for both growth inhibition and cytotoxicity, but was much more pronounced with the former.
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