Patent Number: 
Section: claims

1. A catheter, comprising: a flexible body extending from a proximal end to a distal end thereof,  an x-ray generator disposed in the distal end region of the flexible body for generating radiation in a biologically effective wavelength range, and  a transformer also disposed in the distal end region in proximity of the x-ray generator and electrically coupled thereto, the transformer having a primary winding for receiving an AC input voltage and a secondary winding for generating an AC output voltage for powering the x-ray source. 2. The catheter of  claim 1 , wherein the primary winding receives an AC input voltage having a root mean square (rms) amplitude in a range of about 100 V to about 4 kV, and the secondary winding generates an AC output voltage having a root mean square (rms) amplitude in a range of about 10 to about 40 kV. claim 1 3. The catheter of  claim 2 , wherein the primary winding receives an AC input voltage having a frequency in a range of about 60 Hz to about 10 MHz. claim 2 4. The catheter of  claim 1 , wherein the x-ray generator has a length less than about 30 millimeters. claim 1 5. The catheter of  claim 4 , wherein the x-ray generator has a maximum cross-sectional dimension equal or less than approximately 3 millimeters. claim 4 6. The catheter of  claim 1 , wherein the transformer has a length less than about 50 millimeters. claim 1 7. The catheter of  claim 6 , wherein the transformer has a maximum cross-sectional dimension equal or less than approximately 3 millimeters. claim 6 8. The catheter of  claim 1 , wherein the transformer and the x-ray generator form a monolithic device. claim 1 9. The catheter of  claim 1 , wherein the x-ray generator produces radiation having an energy in a range of about 10 keV to about 40 keV. claim 1 10. The catheter of  claim 1 , further comprising a flexible electrical cable having a diameter in a range of about 1 mm to about 3 mm extending from the proximal end to the distal end for transmitting an AC input voltage from an AC source to the primary winding of the transformer. claim 1 11. The catheter of  claim 10 , wherein the electrical cable comprises a pair of elongate coaxial conductors and an inner insulating layer having a thickness in a range of about 0.01 mm to about 0.2 mm which insulates the coaxial conductors from one another. claim 10 12. The catheter of  claim 9 , wherein the inner insulating layer of the electrical cable can withstand a voltage differential in a range of about 100 V to about 4 kV. claim 9 13. The catheter of  claim 11 , wherein the electrical cable further comprises an outer insulating layer having a thickness in a range of about 0.001 mm to about 0.2 mm which covers the conductors. claim 11 14. The catheter of  claim 11 , wherein the insulating layer of the electrical cable is formed of any of polyethylene, Teflon, or polyimide. claim 11 15. The catheter of  claim 1 , wherein the transformer includes a primary to secondary ratio is in a range of approximately 1/10 to approximately 1/100. claim 1 16. The catheter of  claim 1 , wherein the x-ray generator generates x-ray output power in a range of about 1 mW to about 100 mW. claim 1 17. The catheter of  claim 1 , wherein the x-ray generator comprises an evacuated housing and one or more cathodes disposed in the housing, the cathode being electrically coupled to the secondary winding to generate electrons in response to a voltage applied thereto by the secondary winding. claim 1 18. The catheter of  claim 17 , wherein the cathode is formed of a refractory metal. claim 17 19. The catheter of  claim 18 , wherein the cathode emits electrons during each negative half-cycle of the AC voltage applied thereto. claim 18 20. The catheter of  claim 17 , wherein the x-ray source further comprises an anode disposed in said housing and separated axially from said cathode, the anode being maintained at an electrical potential difference relative to the cathode for generating an electric field for accelerating the electrons emitted by the cathode to the anode such that the impact of the electrons with anode generates x-ray radiation. claim 17 21. The catheter of  claim 17 , wherein the x-ray source further comprises a window disposed in the housing, the window being substantially transparent to x-ray radiation to facilitate transmission of the generated x-ray radiation to outside environment. claim 17 22. The catheter of  claim 18 , wherein the window has a transmission coefficient of approximately 99% for x-ray radiation having an energy in a range of about 10 keV to about 40 keV. claim 18 23. The catheter of  claim 19 , wherein the window of is formed of beryllium and has a thickness in a range of about 10 microns to about 100 microns. claim 19 24. The catheter of  claim 1 , further comprising an insulation casing in which the x-ray generator and the transformer are disposed, said insulation being capable of withstanding a voltage differential of at least approximately 40 kV. claim 1 25. The catheter of  claim 21 , further comprising a beam-forming electrode disposed between the cathode and the anode for focusing electrons emitted by the cathode onto the anode. claim 21 26. The catheter of  claim 22 , wherein the transformer further comprises any of a secondary tap or another secondary winding electrically coupled to the beam-forming electrode to apply an AC voltage thereto. claim 22 27. The catheter of  claim 1 , wherein the transformer comprises a cylindrical core having a diameter in a range of about 0.1 mm to about 2 mm, and a length in a range of about 5 mm to about 30 mm. claim 1 28. The catheter of  claim 24 , wherein the transformer core is formed of a ferromagnetic material. claim 24 29. The catheter of  claim 20 , wherein the secondary winding of the transformer comprises a coil having about 40 to about 1000 turns wound on the core. claim 20 30. The catheter of  claim 26 , wherein the secondary winding coil is formed of a copper wire having a diameter in a range of about 0.01 mm to about 0.1 millimeter. claim 26 31. The catheter of  claim 25 , wherein the primary winding of the transformer comprises a coil having about 5 to about 60 turns wound on the core. claim 25 32. A catheter, comprising: a flexible body extending from a proximal end to a distal end thereof,  an x-ray generator disposed in the distal end region of the flexible body for producing x-ray radiation in a wavelength range effective for treating tissue, the x-ray generator having a maximum cross-sectional dimension equal or less than approximately 3 millimeters,  a transformer also disposed in the distal end region in proximity of the x-ray generator and electrically coupled thereto, the transformer having a maximum cross-sectional dimension equal or less than about 3 millimeter and having a primary winding for receiving an AC input voltage and a second winding for generating an AC output voltage for powering the x-ray source, and  a flexible electrical cable having a diameter in a range of about 1 to about 2 mm extending from the proximal end to the distal end of the flexible body and electrically coupled to the primary winding for transmitting an AC voltage in a range of about 100 V to about 4 kV from an voltage generator to the primary winding. 33. A catheter, comprising: a flexible body having a lumen extending from a proximal end to a distal end thereof,  an x-ray generator disposed in the distal end region of the flexible body for generating radiation in a biologically effective wavelength range, the x-ray generator having at least two cathodes and two anodes,  a transformer also disposed in the distal end region in proximity of the x-ray generator and electrically coupled thereto, the transformer having a primary winding for receiving an AC input voltage and one or more secondary windings for generating an AC output voltage for powering the x-ray source,  wherein the cathodes and the anodes are mechanically and electrically coupled to one another and to the transformer such that one of the cathodes emits electrons during a first portion of each cycle of the AC output voltage to strike one of the anodes and the other cathode emits electrons during a second portion of the cycle to strike the other anode.