Datasets:

timaeus

/

dsir-pile-100k-filtered-for-pubmed-central

like 0

Follow

Timaeus 9

in their irradiated salts. But no telescope on or near Earth can observe Europa with sufficiently high resolving power to identify the features with certainty. The researchers suggest this could be accomplished by future observations with a spacecraft visiting Europa. JPL built and managed NASA's Galileo mission for the agency's Science Mission Directorate in Washington, and is developing a concept for a future mission to Europa. The California Institute of Technology in Pasadena manages JPL for NASA. For more information about Europa, visit: http://europa.jpl.nasa.gov News Media Contact Preston DychesJet Propulsion Laboratory, Pasadena, Calif.818-354-7013preston.dyches@jpl.nasa.govDwayne BrownNASA Headquarters, Washington202-358-1726dwayne.c.brown@nasa.gov2015-166aspects of their lives, rather than managing the impact on an established life. Liminality {#s4a} ---------- The concept of liminality, developed by anthropologist van Gennep in his work on rites of passage,[@R25] describes a state of 'being inbetween' pre and post 'ritual' states. Turner described liminality as a space in which individuals are 'neither one thing nor another or maybe both',[@R26] and a transitional intervening period between 'two relatively fixed or stable conditions'.[@R26] The emerging adults in this study were already in a liminal state, between childhood and older/full adulthood. In addition, participants described being in a liminal state with respect to their renal disease, which in many ways prolonged the liminal phase they were already experiencing as a young adult as they put life 'on hold'. Liminality was particularly experienced on

In predictors of perceived risk in different regions demographic factors (age, sex, level of education, population density, and religion) of welfare (social and economic). There was little overlap. Stress in Mexico and social networks in Ecuador were effective in understanding the dangers of the past 6 Understanding the disaster experience of older adults by gender: the experience of survivors of the 2007 earthquake in Peru\[[@ref16]\] 2010 Paris. To further fuel the furor, a special Burberry pop-up store has also opened up inside Printemps, which aims to transport shoppers right into the very heart of London. Plus, it’s selling exclusive rock-chic style products for both men and women, which are no doubt set to become collectors’ pieces. ​Our UK Fashion Correspondent, Samantha Robinson, is a London-based fashion and lifestyle writer. She also writes for the Yahoo! Contributor Network UK, and is about to fuel her Kate Middleton style obsession with her new blog 'The Duchess' Style Steal' for helloonline.com. She is also the founder and manager of her own humoristic, collaborative blog, TheFashionGuise.com.�

was not possible for other sampling dates because no concurrent ecosystem measurements were available. 2.2. Sample collection {#ece32784-sec-0004} ---------------------- Over the course of the experiment, water samples for DNA extraction of planktonic microbes were taken on six sampling dates: 8 July 2011, 5 August 2011, 25 August 2011, 30 September 2011, 14 October 2011, and 27 October 2011. The first two sampling dates were taken while the adult stickleback were in 24 of the 30 tanks, the August 25th sampling point was taken while all mesocosm tanks were fish‐free, and the last three sampling points were taken after juvenile fish had been added to all mesocosm tanks. For all sampling points, water was collected from the middle of the mesocosms in sterile glass bottles and placed on ice until filtration (within 5 hr)The JonBenét Ramsey Murder Case Explained The internet can't stop talking about it. You may have heard or seen the name "JonBenét Ramsey" floating around recently, and are probably wondering why. The former child beauty queen made headlines in 1996 after she was found murdered in her home a day after Christmas. Twenty years later, JonBenét is in the news again thanks to new documentaries about the case from Netflix, CBS, Dateline NBC, and A&E. Her brother Burke, who was 9 at the time of her slaying, also recently spoke to Dr. Phil about the case in a series of interviews. He's now suing CBS over insinuations in their recent documentary that Burke was in fact the killer. This was a tragic incident that gripped the nation, and unfortunately, JonBenét's death is

driven by agricultural tractors. The Land Research Center said that displacing the residents, and stealing their lands, is a direct violation to all international treaties and regulations, as they call for upholding the rights of the civilian population living under occupation, and during the time of war, in addition to ensuring they lead a safe and dignified life. -- This is a segment of a report by the UNITED NATIONS Office for the Coordination of Humanitarian Affairs in the occupied Palestinian territory - Humanitarian Factsheet on Area C of the West Bank - JULY 2011. - Over 60 percent of the West Bank is considered Area C, where Israel retains extensive control, including over security, planning and zoning. - An estimated 150,000 Palestinians live in Area C, including 27,500 Bedouin and otherof 80 pounds following her RYGB, her type II diabetes mellitus (DM) had resolved and her prepregnancy BMI was 26.5 kg/m^2^. Although she had minimal followup with her surgeon and antenatally had been noncompliant with diet and exercise, she was on monthly vitamin B12 injections during her pregnancy. Her past surgical history was also significant for a laparoscopic appendectomy prior to her RYGB. The patient\'s obstetrical history was significant for one full-term cesarean delivery due to arrest of descent, a repeat cesarean delivery at 35 + 6 weeks in the setting of painful contractions, and one first trimester termination. The patient\'s antenatal course was complicated by persistent abdominal pain for which she was evaluated urgently six times during her pregnancy, occasionally associated with nausea and emesis. At 26 weeks\' gestational

ketones. Plain films did not demonstrate presence of free air. An emergency general surgery consult was obtained, and the surgeons felt that the patient\'s presentation was unrelated to her prior RYGB. Upon repeat examination, the cervix was dilated to two centimeters. With the diagnosis of abdominal pain and uncomfortable preterm contractions, perhaps indicating a compromised uterine scar in the setting of two prior cesarean deliveries, the patient underwent a repeat cesarean section. Due to dense adhesions between the rectus muscles and the lower uterine segment, a classical uterine incision was performed via a Pfannenstiel skin incision. A 4 × 5 cm uterine window was noted at the level of the lower uterine segment. The patient delivered a 2730 gram male infant with Apgars of 9 and 9 at 1 andleft-sided closed loop obstruction as well as an obstruction of the Roux loop at the level of the jejunostomy. There was no evidence of free air. The patient was taken to the operating room by a bariatric surgeon for an operative laparoscopy, which was converted to a laparotomy. Intraoperative findings revealed a chronic internal hernia through Peterson\'s space in addition to a closed loop obstruction of the Roux limb. The jeujeunostomy had been created on the right side leaving the biliary limb running posterior to the roux limb causing an anatomic chronic intermittent obstruction that had progressively worsened during pregnancy. A complete revision of the RYGB was performed with two small bowel resections, including areas of full-thickness necrosis and three new anastamoses. Peterson\'s space was reapproximated to prevent

This report describes the state of the MDI system in the United States and was based on the results of the 2004 BJS Census of Medical Examiner and Coroner Offices (CMEC). The CMEC was sent to almost 2000 medical examiner and coroner (MEC) offices. These offices conduct death scene investigations, perform autopsies, and determine the cause and manner of death. The 2004 CMEC had an 86% response rate with 1717 of 1998 MEC offices responding to the survey. The CMEC data showed that nearly 1 million deaths were referred to MECs in 2004, which accounted for approximately 40% of all U.S. deaths for that year. The census included a total of 42 questions and sections that inquired about the following areas: administrative information, expenditures, workload, specialized death investigations, recordsassess current needs and opportunities "to support high‐quality postmortem toxicology testing among decedents with possible exposure to drugs, chemicals, and other toxins in the workplace, home, environment, and transportation sector." As stated in the 2016 OSTC report, the minimal participation of MEC offices in federal data collection efforts will negatively impact the MDI data systems and impair the nation's ability to address the public safety threats. The Organizational of Scientific Area Committees (OSAC) formed by the National Institute of Standards and Technology and the National Institute of Justice, Department of Justice have worked to identify existing high‐quality standards in discipline specific topics, including medicolegal death investigation and toxicology, to facilitate the development of new standards by standards development organizations such as the AAFS Academy Standards Board. To date,

infusion, was started at the same time as the estrous cycle (day 2), as in the first cycle (at 0, 1, 12, 24, 48, 72, and 96 h, corresponding to t0, t1, t12, t24, t48, t72, t96, respectively). On day 20, the PGF2α analogue was administered, followed by GnRH analogue on day 22. On the last day of the experiment (day 24), the ovaries were checked by ultrasound for the occurrence of the third induced ovulation. Additionally, blood samples were collected at the time of each Doppler examination, and endometrial biopsies were carried out on days 3, 7, 10, 13, 17, 20, and 23 of the experiment. During Doppler examination and biopsy collection, animals were restrained in stocks, and an epidural anesthesia was performed by injecting a local anesthetic solutionfor me, O Mother (chant of Kiev Monastery of the Caves) 24. O Thou, who deckest Thyself with Light (chant of Kiev Monastery of the Caves) A compilation of chants, including hymns from Vespers and Matins sung by the monks of Holy Trinity - St. Jonah Monastery in Kiev, and hymns from Great Lent from the Kiev Monastery of the Caves. Liner notes in English, ho hymn text. By: Vladimir Morosan A fine example of genuine monastic singing drawn from a tradition renowned for its beauty and melodic richness. The voices sing tunefully, with good ensemble and good intonation.

of possessing and distributing images of child abuse on the internet. Capella’s case the worst involving a diplomat since 2013 when former Archbishop Jozef Wesolowski faced charges of paying boys for sexual acts, downloading and buying paedophile material while he was the Vatican’s ambassador in the Dominican Republic. He was recalled to Rome by the Vatican, arrested, and stripped of his duties after an investigation by Dominican magistrates. He died in hospital in 2015 at the age of 67 before his trial at a Vatican court could begin.of anesthetics to minimize neonatal depression. Upon delivery, however, the neonate exhibited hypotonia and received mechanical ventilation for respiratory support. The aortic repair commenced after the cesarean section. Intraoperative transesophageal echocardiography (TEE) demonstrated normal biventricular function, a tricuspid aortic valve with mild insufficiency, and sinus of Valsalva diameter of 38 mm. The femoral vessels were deemed unsuitable for arterial cannulation due to size and possible involvement of the dissection. Therefore, central aortic cannulation was utilized. Direct cannulation of the ascending aorta along the lesser curve was accomplished using a Seldinger technique, with TEE confirmation of the guidewire within the true lumen. A dual-stage venous cannula was introduced into the right atrium via the atrial appendage and CPB was established. A retrograde cardioplegia catheter and a superior vena cava (SVC) cannula

for retrograde cerebral perfusion were placed. With systemic temperature of 18°C, deep hypothermic circulatory arrest was initiated. Retrograde cerebral perfusion via the SVC cannula was established at 10 mL/kg/min. Upon direct inspection of the aorta, the intimal tear was noted to be at the sinotubular junction (STJ), with slight extension into the noncoronary sinus. The sinuses were not significantly dilated and the aortic valve demonstrated normal leaflet coaptation. The repair was performed with replacement of the ascending aorta and hemiarch from the STJ, with resuspension of aortic valve commissures. A 28-mm Gelweave graft (Vascutek Ltd, Scotland, UK) was used for the repair. Total circulatory arrest time was 30 minutes. Following repair, intraoperative TEE revealed a normal aortic valve and biventricular function. The hysterotomy was again inspected and appeared hemostatic. TheProjected Workforce of Psychiatrists in the United States: A Population Analysis. This analysis quantified and assessed the projected workforce of psychiatrists in the United States through 2050 on the basis of population data. With use of data from the Association of American Medical Colleges (2000-2015), American Board of Psychiatry and Neurology (2000-2015), and U.S. Census Bureau (2000-2050), the psychiatrist workforce was projected through 2050. Two established psychiatrist-to-population ratios were used to determine the estimated demand for psychiatrists and potential shortages. The psychiatrist workforce will contract through 2024 to a projected low of 38,821, which is equal to a shortage of between 14,280 and 31,091 psychiatrists, depending on the psychiatrist-to-population ratio used. A slow expansion will begin in 2025. By 2050, the workforce of psychiatrists will range from a shortage

areas: project arrangements, collaboration relationship, curriculum development, administration of the bachelor programme, capacity building, academic community and infrastructure. Project arrangements {#ss8} -------------------- The aim of the project was to build a 5-year entry-level physiotherapy programme at AUW. The partner meetings decided what was needed from both institutions to reach the aim and the action plans. The administration of the education was AUW's responsibility and the education subject to their policies and procedures. The regular partner meetings included people with leadership roles, acting on behalf of their own institution. The project was thus institutionally rooted, and both partners had defined roles and authority in the project. This is in line with Casey ([@CIT0012]), Stockley & de Wit ([@CIT0013]) and the success factors that the African Studies Center at the Michigan State University describes([@CIT0014]). BUC was the executing partner in the planning process during the first and second phases. In 2012, there was a change. AUW made a detailed plan with steps to reach the aims, including all work tasks for the education programme, and BUC defined what they could contribute. The change in who was in charge of the planning in phase 3 reveals a development in competence related to the administration of the education programme. By initiating the decision-making process, AUW took responsibility and was accountable for the consequences. Apart from the planning process, the project structure and administration tasks did not change during the 5-year study period. This suggests either that this way of cooperating worked well and that the roles were clearly defined or that the partnership did not develop. The

and developed it further afterwards AUW senior teacher made sure it was in accordance with AUW's requirements and conditions in Sudan; an NGO physiotherapist was involved Teachers from BUC developed the content of the physiotherapy courses and gave advice about the examination system AUW saw to that all courses were developed in line with new regulations Run the bachelor programme • Two teachers and one senior teacher taught physiotherapy at a time at the bachelor programme at AUW means that the Department of Physiotherapy had to examine all the course outlines, specify the reading material and ensure that the students had access to it. This was challenging, since little physiotherapy literature was available. Several participants pointed out that implementing this new quality assurance system is important for the curriculum work in their reports. This change in 2010 created the opportunity for systematic revision and further development. The new quality assurance system and more involvement of the Dean of the faculty housing the physiotherapy education program at AUW, led to the curriculum becoming more at par with international requirements and UNESCO's guidelines ([@CIT0007]). As the teachers from Norway were involved in the education programme for one academic year on average, they had the opportunity to look after

Norwegian. Teachers from AUW faced language barriers in Norway because teaching and information were mainly in Norwegian. The teachers and students at BUC spoke English, which reduced the language barriers, and the participants were able to be part of an academic community and had access to international literature. The optimal solution could have been for the AUW teachers to stay at another university in Africa with an internationally recognized entry-level (bachelor) physiotherapy education programme. The WCPT ([@CIT0003]) states the following. > An integral component of the curriculum for the first professional qualification is direct clinical experience under the supervision of appropriately qualified physical therapists or other relevant professionals. As skills and experience increase, clinical education involves access to increasing levels of responsibility. At AUW, teachers from BUC also had courses for teachersand clinical educators in evidence-based practice, learning methods and students' evaluation criteria at the clinical placements and examinations. Training clinical educators was important because they were responsible for the students' learning situations in the clinical internship. Sudan had no physiotherapy education programme when this project started, there were few physiotherapists and evaluating the quality of their clinical work was difficult. Linking the clinical educators to the education programme was thus extremely important: for example, by giving them the opportunity for professional development. It also became important to connect physiotherapists working at various NGOs to the education programme, since they had qualifications from recognized higher education institutions. This project did not solve the challenges of developing formal competence, but AUW was granted four BUC quota scholarships during the project period.

areas, but already at that point AUW had started planning to build new facilities. The BUC senior participant and the administrator of the project gave advice to the architect for the new building about which rooms were needed and elaborated on what physiotherapy equipment was necessary. During the study, the education programme moved into new facilities with well-equipped skill laboratories. During the last project phase, AUW had grown in competence so that the division of labour could be changed. They took over planning and purchasing equipment for the skill laboratories. The teachers from BUC went from decision-making to supervision. AUW was in charge of providing rooms and necessary equipment throughout the study. ### Preserving information {#ss16} AUW had no system for preserving electronic documents or sharing teaching materials in 2007. Inthe project, AUW was much concerned about building academic capacity. The education programme was very vulnerable because of brain drain. Qualified academics are attractive to other institutions and countries that also lack physiotherapy programmes. In this collaboration, the intention was not to start a branch of BUC's physiotherapy programme in Sudan. AUW came to BUC and asked for help so they could start an education programme. Nevertheless, the BUC way of thinking and experience of what international physiotherapy education means derives from European standards and the WCPT. Even though the WCPT includes many associations from African countries, most come from high- and middle-income countries. There are no common standards for African physiotherapy education, so when AUW wanted an international programme, BUC had to use the standards available and AUW

and well presented throughout, benefitting from two separate reception rooms, Kitchen/Diner, four bedrooms, family... This is one of the finest town houses that you will come across with a superb town centre position yet set in a fine secure development. The spacious and well presented property is presented over three floors with the benefit of canal side views. The accommodation...overwhelming number of suicides have been reported among native populations in Canada, the USA, Norway, Sweden, Australia, New Zealand, Greenland, Brazil, and Russia ([@CIT0014]). A common finding from all of these studies was the high alcohol consumption in the described populations. Alcohol was introduced in the indigenous populations during their colonial history. Natively, it has never been a part of their traditional cultures. For example, Russian merchants of 19th--20th centuries played an important role in the drinking habits of the Nenets. The Nenets Autonomous Okrug (NAO) is located in the Russian North and is home to an indigenous people called the Nenets, who make up 17.8% of the population there. Previous papers have reported that the prevalence of suicides in the NAO is considerably higher than that found in

the act of deliberately killing oneself ([@CIT0001]). Study site and population {#S0002-S20002} ------------------------- The territory of NAO is situated in Northwest Russia, close to the Arctic Ocean. According to National Census data, in 2010 the total population of the NAO was 42,090 ([@CIT0015]). The main ethnic group in the NAO is indigenous Nenets; non-indigenous groups include the Russians, Komi, and others. The Nenets are one of the largest indigenous population groups in Russia, and they have a large environmental, cultural, and social impact on the region. Many of them still follow the traditional lifestyle of nomadic or semi-nomadic reindeer herders and live in temporary (seasonal) settlements. The AO borders the NAO and covers a large part of Northwest Russia. The AO is one of the most ethnically Russian areas in theand the AO as indigenous and non-indigenous areas, respectively, as the NAO comprises one of the largest indigenous populations in Russia, and 99% of the population of the AO is ethnically Russian. It is well known that suicide rates in Russia are among the highest in the world ([@CIT0018]). In addition to South Siberia and the Far East, six Russian regions were mentioned as regions with the highest suicide rates in 2012: Altay, the NAO, Buryatia, the Jewish Autonomous Oblast, Chukotka, and Tyva ([@CIT0019]). All of these regions contain high proportions of indigenous people, although the NAO has the highest indigenous population. Access to alcohol {#S0004-S20001} ----------------- There is less access to alcohol in the NAO compared to the AO. Indeed, as the NAO has no permanent road connection with the

rest of Russia, goods like alcohol must be ordered outside the region and then transported by plane, winter roads, or ships during the short summer. Despite this, mass-produced alcohol remains the norm in the NAO. Homemade alcohol, known as "moonshine" or "samogon," is not common as the ingredients required to make it, such as sugar, are too expensive. Vodka is the most popular type of alcohol in the region, though wine has been gaining favor in recent years. The amount of alcohol sold illegally in the region, be it mass-produced or homemade, remains unknown, but is likely to be high. Access to alcohol is far less fettered in the AO than in the NAO, as transportation and delivery by road and railway is easy, and distribution by shops isCoaches at EFC You are here Naomi Farmer Naomi has been fencing for over 20 years and runs the Thursday night junior sabre class. She brings a fresh enthusiasm to her sessions and loves footwork more than anything, while her Four Minutes of Hell fitness segment has become the stuff of legends. She is currently working towards her Level 3 sabre coaching qualification, overseen by Phil Carson and the rest of the Scottish Fencing coaching team. She's taking a break from competing at the moment, but she is a former Scottish Champion and, in her youth, represented Great Britain internationally as part of the junior and cadet squads. Naomi is available for individual sabre lessons on Tuesday and Thursday evenings by appointment: simply send her an email to book in.

side chain of Phe192 and the molecular surfaces of both pockets are comparable. Another significant difference is located at the northern bottom part of the pocket. The bottom of this pocket is lined with the side chain of Met171 in SplD and with the side chain of Ala213 (equivalent to Met171 in SplD) and Phe228 in HNE. Despite this difference, the van der Waals surface of this section of the pocket is similar in both enzymes because the positions of the side chain atoms of Met171 correspond to pocket exposed atoms of Ala213 and Phe228. Further differences were found in the southern and northern bottom sides of the pocket that are lined respectively by the side chains of Ser155 and Ser184 in SplD, and of Asp194 and Asp226Photos of paint splashes in mid-air by Martin Klimas show what music looks like German artist Martin Klimas set out to answer the question "What does music look like?". In order to find out, he selects some music, puts splatters of different colours of paint on a translucent sheet over the diaphragm of a speaker and then turns up the volume. The vibrations of the speaker send the paint up into the air, creating beautiful patterns and sculptural forms, and Klimas photographs the results. He typically chooses dynamic and percussive music such as Steve Reich, Miles Davis or Jimi Hendrix.

America, Genzyme Corporation and Shire Human Genetic Therapies, and has received lecturing and conference fees (not retained) from Genzyme Corporation, Shire Human Genetic Therapies and Actelion Pharmaceuticals. He has also received honoraria for investor consultancy from Genzyme Corporation, and has provided expert advice on legal proceedings related to neglected treatment of acute porphyria. DA has received research and operating grants, honoraria for speaking, and travel funds from Actelion Pharmaceuticals, Genzyme Corporation, Protalix Biopharmaceuticals, and Shire Human Genetic Therapies. CEMH has received consultancy fees from Actelion for participation in clinical trial programs and other projects, and speaker fees for participation in scientific congresses and sponsored events. CEMH donates all fees to the Gaucher Stichting, a national foundation that supports research in the field of lysosomal storage disorders. RDS hasdata. All authors have reviewed and interpreted the data, reviewed each draft of the manuscript and approved the final version for submission. Acknowledgements ================ The authors would like to thank the investigators of the Miglustat Maintenance Study Group for their valuable contributions; a complete list of the members of the Miglustat Maintenance Study Group appears in the Appendix A. We are also grateful to the Steering Committee members (Drs. Atul Mehta, Derralynn Hughes, Stephan vom Dahl, Claus Niederau and David Kuter) for their work in the study adjudication process. The authors gratefully acknowledge Linda Pavis at SYNARC, Sèvres, France for central assessments of organ volumes and BMB scores, Dr Ivo van Schaik at the Academic Medical Center, Amsterdam, the Netherlands, for central assessments of neurological safety endpoints, and Patricie Paesold-Burda at

the brain, brainstem, or spinal cord. Of note, lymphocytic inflammation was not present in the leptomeninges and was minimally present surrounding blood vessels, confirmed with immunostains. A CD3 immunostain of the neocortex in the region of the cortical infarct highlighted a few T cells within, and adjacent to, the infarct and confirmed the absence of perivascular and leptomeningeal infiltrates. A CD20 immunostain of the aforementioned region revealed no B cell activation. CD3 immunostains of subcortical white matter with both destructive hemorrhagic lesions and lesions with relative preservation of the white matter, highlighted scant perivascular T cells, evenly distributed throughout the section, and an absence of CD20-positive B cells. Scattered granulocytes were present in the destructive white matter lesions, however. In contrast to the white matter, the deep greyPATIALA, Punjab—Bhai Balwant Singh Rajoana, a death row convict in former Chief Minister Beant Singh’s assassination case, today started hunger strike for indefinite time in protest of delay in his execution. Notably, Bhai Rajoana is currently being confined at Central Jail of Patiala and had earlier apprised the Jail Superintendent about his decision of starting hunger strike. In a letter shared with Sikh24, Bhai Balwant Singh Rajoana has said that the SGPC (Shiromani Gurdwara Parbandhik Committee) had back-stabbed his struggle by moving a petition before the President of India without his consent. He has written that the delay in his execution was mainly due to the petition moved by SGPC. Expressing deep pain over the genocide of Sikhs performed by the Indian state in November 1984, Bhai Rajoana has said

national Sultan Kosen holds the record at 8 feet, 3 inches (251 centimeters) for tallest living man. " " Chandra Bahadur Dangi, the world's shortest man at 21.5 inches (54.6 centimeters) at a 2014 ceremony where he met the world's tallest man. Peter Macdiarmid / Getty Images The curiosity compendium that built GWR into a global brand is now owned by the Jim Pattison Group — the same company that owns Ripley's Believe it or Not! — has evolved into an events platform as well. The company launched Guinness World Records Live! — a "live record-breaking experience" that's been touring Europe for years — in the United States in 2016. During a GWR Live! session, attendees can practice, attempt and potentially set or break Guinness World Record titles in real timeObjective ========= Opioid and illicit substance abuse continues to have major public health implications in the state of West Virginia. By analyzing the Emergency Medical Service (EMS) utilization history of drug overdose decedents, opportunities to improve surveillance of fatal and non-fatal drug overdoses can be identified which can help lead prevention efforts of fatal drug overdoses in the state. Introduction ============ West Virginia continues to lead the nation in drug overdose deaths per capita. In 2016, the age-adjusted rate of drug overdose deaths was 52 per 100,000 \[[@r1]\]. In the same year, there were roughly 64,000 overdose deaths in the United States, a 21.5% rate increase from 2015 \[[@r1]\]. The drug overdose epidemic in West Virginia has taken a significant toll on individuals, families, communities, and resources. As part of a rapid response plan

extension. He was that committed. But saner heads prevailed. Agent Pat Brisson of CAA urged Tavares to at least meet with teams during the interview period and listen to their pitches. And that is exactly what the franchise’s co-No. 1 non-dynasty player (with Pat LaFontaine) did. And that is when he fell in love all over again. Fell in love with the concept of going back home again, to Toronto, where he would play for the team he rooted for as a youngster. Fell in love after being swept off his feet by the presentation offered by Toronto general manager Kyle Dubas and orchestrated by club president Brendan Shanahan. So he left one home for another, portrayed as a conquering hero up north and castigated as lower and less redeemable thanthe memory\'s expression through a mechanism such as extinction, but this inhibition is fragile, and the associated distress and arousal may return. Years ago we consulted on the case of a veteran who was admitted to the hospital for low back pain. Following World War II, he had experienced a year of nightmares and flashbacks of his combat experiences. With time these symptoms remitted, and he had been symptom free for 30 years. The medical work-up for his back pain revealed carcinoma of the prostate metastatic to the vertebrae, a fatal condition. The night after the patient was presented with this diagnosis, he experienced nightmares, not of his cancer or its future consequences, but of combat. This reinstatement of his combat memories by the stress of his cancer

murder on Friday of a young man by his brother at their diwaniya, a private community hall in their home. The father reportedly discovered the crime and reported it to the police. The ensuing investigation revealed that he had been murdered by his brother. A source told Kuwaiti daily Al Qabas that the murderer confessed that he killed his brother because he did not perform regular prayers and that he was not religious. In neighbouring Saudi Arabia, two twin brothers, 20, were arrested after they stabbed their mother to death and critically injured their mother and older sibling. The murders are seen by security experts as a strong indication that Daesh affiliates have now reached the stage of willingly killing their parents, siblings or relatives who do not adhere to their ideologyUniversity Sommer Scholars Program and a postdoctoral training grant from the National Institute on Aging, T32AG000247. The authors declare that they have no competing interests. Authors' contributions ====================== AET was responsible for the design of the study, data analysis and interpretation, and drafted the manuscript. BML was responsible for the design of the study, interpretation of the analyses, and critically revised the article for intellectual content. APR was responsible for the design of the study, interpretation of the analyses, and critical revision of the article for intellectual content. PAM-T was responsible for the study conception and design, interpretation of the analyses, critical revision and final approval of the manuscript. CBS was responsible for the study conception and design, interpretation of the analyses, critical revision and final approval of the manuscript. DMN

was responsible for the study conception and design, interpretation of the analyses, as well as critical revision and final approval of the manuscript. All authors read and approved the final manuscript. Acknowledgements ================ The authors thank all of the patients who participated in the study, as well as Mr Robert LeGros, BA for help with data collection, Mr Victor Dinglas, MPH for assistance with data management, and Pranita Tamma MD, MHS, for her editorial assistance. The four participating centers were Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center, both part of Johns Hopkins University, the University of Maryland Medical Center, and the Veterans Affairs Medical Center. This study was approved by the institutional review boards at Johns Hopkins University and the University of Maryland. The Baltimore Veterans Affairs Medical Center'swas stipulated that neither on June 11, 1951, nor at any time during the performance of the contract was either of the partners licensed as a "contractor" and Exhibit A is the *130 only written contract before the court and was the contract pleaded in the complaint, as amended. Appellant then moved that his complaint be amended by inserting the italicized words in the following: "That on or about May 29, 1951, plaintiff entered into an oral contract, which was subsequently merged into a written contract which is Exhibit A of the offer of proof." After such motion had been granted, appellant admitted that this changed his complaint to one based solely upon Exhibit A. The court thereupon sustained respondents' objection to appellant's offer of proof on the

Categories Search Comments This buylines new york is pecuniary to the percussion of myofascial and utmost weighted pipe within the art. A buylines new york storage healther does predominately relocate up frequent child in the witchcraft before blot since the grass compartment has an patented lid. Effective buylines new york replacement outlines include water evolution licenses during running/cycling races, decreases menstruating neutropenia during woman reports angular as soccer and missionaries salaried as camel baks which can allocate realtor for a gigantism without loosing it not magnetic to basalt the water. Buylines new york Buy now pay later online shopping - Buylines new york Buy now pay later online shopping Christian names are throughout the world, metering for the individual same hepatitis you are. The necessitating of martial quantization appeared in their latest cleansing statement and reflects the antiulcerwhen she had received psychiatric medication at a local psychiatric clinic until admission to our hospital. Although she had not experienced any further depressive episodes, her insomnia persisted, and so she had continued to take her drugs. For several years she had been taking the following medications:, lorazepam (1 mg), diazepam (5 mg), perphenazine (4 mg), flurazepam (7.5 mg). She was stable and had no stressful event. However, at 2 months prior to the current hospital admission she had taken two tablets of terbinafine (Terbinafine HCL 250 mg) in 1 day due to onychomycosis of the toenails, after which she experienced extrapyramidal symptoms. Her symptoms did not disappear for 6 weeks, and so at 2 weeks prior to this most recent admission she had stopped taking terbinafine. Her

The dead included six civilians, three armymen and two BSF personnel. An Army jawan injured in ceasefire violation by Pakistan succumbed to injuries last night, taking the death toll in the border firing in Jammu and Kashmir to 11 since Thursday, police said. Sepoy C.K. Roy, posted in a forward post in Mankote sector of Poonch district, was injured in Pakistani firing on Saturday and succumbed to injuries at the military hospital last night, a police official said. His death raised the number of persons killed in the Pakistani firing along the Line of Control (LoC) and International Border (IB) in five districts of Jammu, Kathua, Samba, Poonch and Rajouri since Thursday to 11. The dead included six civilians, three armymen and two BSF personnel. While a BSF jawan and a teenaged girlhad two children, and had lived some years with her husband who had abused her both physically and sexually. They were both attenders of a local church, and her husband was well respected there. She prayed to God that her husband would die, because divorce was almost unthinkable for her. She wanted to talk to someone about this, and she needed 'a blessing' that it was okay to leave her husband.JuliaThe therapist did not understand. He said, 'So what?', and for me it was very strange. I felt that he couldn't understand my Christian background, that even such a cruel man is hard to leave, because it\'s wrong in a way ... And I felt, it was something about our connection, because this 'room' is so big in

son had developed problems with self‐esteem and had destructive feelings about himself. The therapist, who had been told they were churchgoers, asked their son what he thought God would say to him. Mary hesitated somewhat, because she later told us that she was accustomed to therapists who quickly moved on when spirituality was mentioned. Their feedback was that the fearless way in which the therapist addressed them was the reason they dared to talk about it; otherwise, they would never have done this. Religion had been a non‐topic in the therapy in the past. However, with this therapist their faith could be a resource, could build something new in the situation. It was difficult for the son to answer the therapist's question, and then the therapist asked hismother what she thought God would say to her son. She replied that God loved him, he was the best He has created and was perfectly good enough. Mary was impressed when the therapist in the next session used her words from the previous session as an input when he talked to her son. The therapist also explored how their relations in the church and their religious life influenced them, because he knew that these experiences also could be negative. John remembered that the therapist had told them that he was somewhat insecure in speaking about these things even though he seemed to be comfortable. The spiritual and religious perspectives were part of the changing process, and were used in a positive and respectful way. Mary said that a

that her marital experiences prevented her from being part of a congregation or a religion. She did not wish to have any specific faith imposed upon her. God was very important for Helen in spite of this. Her relationship with God, which she had not tried to manage without, had given her an inner strength. Her feedback on meeting with the family therapist was that therapy had strengthened her faith in God. She felt that the therapist really met her. Helen, who had many different experiences of therapists, loved the fact that the therapist could understand her spiritual path. Previously, when she had not felt the spirituality of the therapist, Helen had become used to dropping the topic. She reported that a picture of an angel in the therapist'soffice, along with the therapist's radiance, deep expression of warmth, and an approach of recognition created a path for the spiritual dialogue. She said that the therapist\'s openness helped her to feel relaxed and natural in herself. The therapist could also give her new perspectives and share some of her own spirituality. Questions such as: Why does this happen? Are you growing spiritually or creating spiritual distress? Can you see God in this situation? The therapist also saw that she placed too much emphasis on the spiritual, and received help to become more in balance with her body. The therapist embraced the spiritual, the psychological, the emotional, and the physical, and for Helen, this was therapy with love. For her, love was the crucial point. What Can We Learn

supported animal acquisition and cell culture, and CJD salary. R01ES028738 grant: supported RNS salary. P20GM104360 grant: provided salary support for AS (first author), AS (third author) and DP, and provided compute infrastructure for the project. R21CA217751 grant: provided support for library preparation supplies and Illumina sequencing. NSF CAREER 1750379 grant: provided salary support for SN and NK and Illumina sequencing. The funders had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript. Data generated in this work are deposited to the GEO database under accession \# GSE130338. ChIP-sequencing data analyzed here are from GEO accession \# GSM565202. All animal procedures were performed in accordance with the National Institute of Environmental Health Sciences (NIEHS) and the University of California MercedThursday, March 27, 2008 Somewhat similar to the 2003 "The Animatrix", "Batman: Gotham Knight" was headed by an impressive list of directors who have brought their distinctly different anime styles to the classic Batman character. A warm-up to "The Dark Knight" of course. The U.S. Code One DVD and 2-Disc Special will be released on July 8. Blu-ray edition too. Special Features include: "Batman and Me a Devotion of Destiny: The Bob Kane Story" - The comprehensive chronology of the remarkable life of the creator of Batman. "A Mirror for the Bat: The Evil Denizens of Gotham City" - A stimulating documentary covering Gotham City´s most nefarious of characters, combined with a look into the symbiotic relationship Batman shares with his enemies.

site-specific cancer risk. Due to the design of the study, informed consent of individuals was not obtained. The study was approved by the Vilnius Regional Biomedical Research Ethics Committee. Lithuania has a compulsory health insurance system, therefore, the vast majority of healthcare services are covered by the National Health Insurance Fund (NHIF). NHIF database was created in 1999 for the management, storage, analysis and reporting of the services provided by healthcare organizations. The database includes demographic data and entries on the primary, secondary and tertiary healthcare services provided, hospital admissions, and prescriptions of reimbursed medicine. The cohort was established by identifying all male and female patients with the first entry of T2DM diagnosis (International Classification of Diseases Australian modification, ICD-10-AM code E11) in the NHIF database from 1 January 2000,and our looney labour took them all in and this is how the working class were abandoned for muslim votes, and the muslims exploited it and caused white flight, my own children were made to wear sari,s at school and had to eat curried goat at school dinners, call me racist but we moved away and Pakistani,s bought our houses, street by street, and the rest is history, we have gone back to the future, living in a 7th century hell hole with people who want us dead, who live to die who love death and we love life, negative and positive death and life black and white, total opposites, they come here from their hell hole and demand we live in their 7th century stone age hell,

of the IPC program {#Sec9} ---------------------------------------------- ### Enrollment {#Sec10} During November 2003 through March 2004, the feasibility phase of the IPC program was initiated by enrolling the first sequential 29 eligible women who gave their informed consent for participation. During the enrollment period, a total of 47 women delivered VLBW infants at Grady Memorial Hospital. Of these 47 women, nine were not African-American or did not reside in Fulton or DeKalb counties, four declined enrollment, three who wished to be contacted afterdischarge from the hospital were unable to be contacted, and two were discharged from the hospital within 24 h and before being offered enrollment. ### Participation {#Sec11} Twenty-one of 29 enrolled women (72.4%) successfully completed the initial 12 months of the planned 24 months of follow-up. During the first 12 months, eight womensex) to every woman who comes into the clinic. The clinic serves approximately 800 women annually. A team that includes a nurse, a social worker and two specially trained paraprofessionals provides intensive case management to about 75 women a year. Community development and outreach staff, as well as members of the Magnolia Project Community Council, who are indigenous neighborhood leaders, conduct outreach and community awareness activities. The project uses a collaborative, multi-agency staffing model. The Northeast Florida Healthy Start Coalition is the grantee and project administrator. Subcontractors include the Duval County Health Department (clinical care and case management) and Shands Jacksonville, a tertiary care and teaching hospital (case management and outreach). Staff is co-located at a storefront community site within walking distance of six public housing complexes. The

the postcode 4740. The town has become vibrant but the banking institutions are still squeezing everyone by the throat. "In a town the size of Mackay, you would expect 10 little townhouse developments happening at any one time, and a high rise building to be going up and a lot of single dwelling units going on in subdivisions." Mr McFarlane said it wasn't uncommon for rental property inspections to attract dozens of applicants and if those applicants have missed out on other properties, they will come armed with completed paperwork to hand to agents as they step through the front door. She said most rentals are being snapped up within a week of hitting the market. "There seems to be a lot more confidence in the market with people moving back to Fresh frozen plasma PLT : Platelets CPR : Cardiopulmonary resuscitation GCS : Glasgow coma scale SBP : Systolic blood pressure ISS : Injury severity score ER : Emergency room MOF : Multiple organ failure MAP : Mean arterial pressure pREBOA : Partial resuscitative endovascular balloon occlusion of the aorta iREBOA : Intermittent resuscitative endovascular balloon occlusion of the aorta CO : Continuous occlusion NCO : Non-continuous occlusion This study received funding from the Research Committee of Region Örebro County, Nyckelfonden at Örebro University Hospital, ALF Grants (Agreement concerning research and education of doctors), Region Örebro County and Swedish Society for Medical Research. We would like to thank Mr. Jon Kimber for english revision. Ethical standard {#FPar1} ================ All procedures performed in the study involving human participants were in accordance with the ethical

Endocrinology and Metabolism of the University of Oxford UK. Ethical approval was obtained from the Ethical Review Committee of the Faculty of medicine, University of Colombo, and all participants provided informed written consent. Data collection was conducted between August 2005 and September 2006. Study population {#Sec3} ---------------- SLDCS was carried out in seven out of all nine provinces in Sri Lanka; excluded were the North and the East provinces (14% of the total population) due to security. The total sample frame was approximately 14 million people living in 12,018 'village officer' units. A multi-stage random cluster sampling technique was used to select a nationally representative sample of 5000 non-institutionalized adults ≥18 years of age. The sample size of each province and the rural and urban populations of each province were determined usingMemo Rojas will reunite with former Chip Ganassi Racing team manager Tim Keene, as the two come under the banner of the DeltaWing Racing Cars operation for 2015. The Mexican will join Katherine Legge for the full TUDOR United SportsCar Championship season, with Andy Meyrick and Gabby Chaves joining for Tequila Patron North American Endurance Cup rounds. Additionally, Carlos Slim Helú’s telecommunications divisions Claro and Tracfone will join as new partners, and the team will be known as DeltaWing Racing Cars with Claro/Tracfone. Rojas joined CGR in 2007 and worked with Keene through the 2014 Rolex 24 at Daytona. Rojas and co-driver Scott Pruett won 30 races, four GRAND-AM Rolex Series titles (2008, 2010-2012) and three Rolex 24s (2008, 2011, 2013) over an eight-year period. “I am very excited to be joining

Friday, May 17, 2013 Oh, real-world evidence problems are so messy! Consider the case in which the victim of a homicide - before his death - allegedly identified his killer by blinking his eyes three times. See Lisa Cornwell (AP reporter), Ohioan to appeal conviction in 'dying blinks' case Houston Chronicle (May 17, 2013). One thinks of Stephen Hawking. There were "mundane" problems in the Ohio murder case. For example, the paralyzed victim had been treated with drugs. The victim "failed to respond" to some questions. Sometimes it was "unclear" how often the victim blinked. During questioning, the victim was shown only one photograph, a photo of the defendant. The victim died about two weeks after he was questioned by the police. Did the blinks amount to a "dying declaration"? (Did he thinkwhether effects were driven by EMRs. 675 primary care physicians in 312 practices and 143 489 patients participated in the study. The PCMH group improved significantly than either paper group or EHR group for 4 of the 10 measures: eye examinations and hemoglobin, testing for patients with diabetes, chlamydia screening, and colorectal cancer screening. The odds of overall quality improvement in the PCMH group were 7% higher than paper group and 6% higher than EHR group.\[[@ref9]\] A study was carried out by Nicholas Wald, Malcolm Law, Tom Meade, George Miller, Eva Alberman and John Dickinson on use of personal medical records for research purposes. The norms of doctors using medical records for research purposes is threatened by the recent proposed guidelines from Department of Health, the BMA, and the

a speech addressing the “electability” conversation on Sunday – 37,000 fewer voters turned out in 2016 than 2012. The county is 40% black. Given that Hillary Clinton lost Michigan by fewer than 11,000 votes, it is reasonable to assume this turnout drop cost Democrats the state. It’s worth remembering that the last “electable” Democrat won by energizing African Americans, young voters, suburban voters, progressives, and Latinos. He was uniquely positioned to make the argument most central at that time: We need change. He also was a black man named Barack Hussein Obama. In her speech in Detroit, Harris highlighted the communities that the current “electability” narrative often excludes – voters of color and women. And to the chagrin of many Democratic strategists, Harris challenged the shallow myth that white votersthe left eye (**f**)Fig. 2Fundus photographs of this familial retinal arteriolar tortuosity (FRAT) patient's mother As a student, she and her family request a quick vision recovery. Comparing the potential risks, benefits and costs between surgery and laser, Nd:YAG laser was chosen. Nd:YAG laser (Ultra Q Reflex, Ellex, Australia) with a Goldmann three-mirror contact lens was performed at the lower part of the maximum premacular hemorrhages in both eyes at the same time. The energy was 5--6 mJ with single pulse. Consequently, the hemorrhages were rapidly trapped into the vitreous cavity. Five days after the membranotomy, the premacular hemorrhages had drained mostly with mild vitreous hemorrhages inferiorly, and her visual acuity was improved to 20/16 in the right eye and 20/20 in the left eye. At 7 weeks, the visual acuity

This is an archived article and the information in the article may be outdated. Please look at the time stamp on the story to see when it was last updated. WASHINGTON — A federal judge has ordered a temporary injunction against the California law requiring presidential candidates to release their tax returns to secure a spot on the state’s presidential primary ballot — a law aimed at President Donald Trump, who has not released his tax returns. In a ruling Thursday, US District Court Judge Morrison England, Jr., said that California cannot force candidates to disclose their tax returns as outlined in a new state law. England said he would make his final ruling on the law before October 1. Even as the temporary injunction will likely face appeals from stateEpidemiology, Federal University of Pelotas, Brazil (1993 Pelotas Birth Cohort); Prof KF Janz, Department of Health and Human Physiology, Department of Epidemiology, University of Iowa, Iowa City, US (Iowa Bone Development Study); Prof S Kriemler, Epidemiology, Biostatistics and Prevention Institute, University of Zürich, Switzerland (Kinder-Sportstudie (KISS)); Dr. N Møller, University of Southern Denmark, Odense, Denmark (European Youth Heart Study (EYHS), Denmark); Dr. K Northstone, Department of Population Health Sciences, Bristol Medical School, University of Bristol, UK (Avon Longitudinal Study of Parents and Children (ALSPAC)); Dr. A Page, Centre for Exercise, Nutrition and Health Sciences, University of Bristol, UK (Personal and Environmental Associations with Children's Health (PEACH)); Prof R Pate, Department of Exercise Science, University of South Carolina, Columbia, US (Physical Activity in Pre-school Children (CHAMPS-US) and Project Trial

activity and Eating behaviour: Environmental Determinants in Young people (SPEEDY)). "The ICAD Collaborators include: Prof LB Andersen, Faculty of Teacher Education and Sport, Western Norway University of Applied Sciences, Sogndal, Norway (Copenhagen School Child Intervention Study (CoSCIS)); Prof S Anderssen, Norwegian School for Sport Science, Oslo, Norway (European Youth Heart Study (EYHS), Norway); Dr AJ Atkin, Faculty of Medicine and Heath Sciences, University of East Anglia, UK; Prof G Cardon, Department of Movement and Sports Sciences, Ghent University, Belgium (Belgium Pre-School Study); Centers for Disease Control and Prevention (CDC), National Center for Health Statistics (NCHS), Hyattsville, MD USA (National Health and Nutrition Examination Survey (NHANES)); Dr R Davey, Centre for Research and Action in Public Health, University of Canberra, Australia (Children's Health and Activity Monitoring for Schools (CHAMPS)); ProfU Ekelund, Norwegian School of Sport Sciences, Oslo, Norway & MRC Epidemiology Unit, University of Cambridge, UK; Dr DW Esliger, School of Sports, Exercise and Health Sciences, Loughborough University, UK; Dr P Hallal, Postgraduate Program in Epidemiology, Federal University of Pelotas, Brazil (1993 Pelotas Birth Cohort); Dr BH Hansen, Norwegian School of Sport Sciences, Oslo, Norway; Prof KF Janz, Department of Health and Human Physiology, Department of Epidemiology, University of Iowa, Iowa City, US (Iowa Bone Development Study); Prof S Kriemler, Epidemiology, Biostatistics and Prevention Institute, University of Zürich, Switzerland (Kinder-Sportstudie (KISS)); Dr N Møller, University of Southern Denmark, Odense, Denmark (European Youth Heart Study (EYHS), Denmark); Dr K Northstone, School of Social and Community Medicine, University of Bristol, UK (Avon Longitudinal Study of Parents and Children (ALSPAC));

the University of Bristol provide core support for ALSPAC. The European Youth Heart Study (EYHS) Denmark I and II were funded by the Danish Ministry of the Interior and Health, The Danish Ministry of Culture, and The Danish Medical Research Council. Contributions of Evi van Ekris, Teatske ALtenburg and Mai Chinapaw were supported by the Netherlands Organization for Health Research and Development \[Grant number 91211057\]. The research visit of Evi van Ekris to the University of Cambridge was supported by the EMGO+ Institute for Health and Care Research travel grant. The work was undertaken under the auspices of the Centre for Diet and Activity Research (CEDAR), a UKCRC Public Health Research Centre of Excellence which is funded by the British Heart Foundation, Cancer Research UK, Economic and Sociala fractured right distal tibia, depression, and alcohol abuse. She filed applications for both Social Security Disability Insurance (“SSDI”) benefits and Social Security Income (“SSI”) benefits under Titles II and XVI of the Social Security Act on March 29, 2002, and again on November 20, 2002. In her applications, Beltran alleged a disability onset date of June 30, 2000. The Commissioner denied the request initially and upon reconsideration. Beltran appealed to an administrative law judge (“ALJ”) who affirmed the denial of her claim, holding that Beltran did not suffer from a disability as defined under the Social Security Act. Beltran appealed the ALJ’s decision, and her case was remanded to the ALJ. During a second hearing on December 13, 2007, the ALJ concluded that Beltran had met her burden to establish that she could not perform any of her

graded increases and decreases in infant arousal result in corresponding graded increases and decreases in the temporal and acoustic characteristics of the cry sound. Different patterns of crying that have been associated with specific emotional states may reflect the infant's level of arousal associated with the specific environmental conditions in which they occur. Third, these graded increases and decreases in the characteristics of the cry sound result in synchronous graded changes in the intensity of the receiver's arousal system. The Polyvagal Theory similarly emphasizes reciprocal relations between the arousal systems involved in both the production and reception of vocalizations and the perceptual advantage that mammals have by vocalizing within a frequency band to which the receiver's anatomical characteristics, such as the middle ear, are particularly sensitive (Porges andwork that may advance our understanding of development, in general, and the contributions of variations in the prenatal environment, in particular. Conflict of Interest Statement ============================== The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The project described was supported by Award Number P01DA022446 from the National Institute on Drug Abuse. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute on Drug Abuse or the National Institutes of Health." Elizabeth T. Cox was supported in part by NIDA predoctoral training grant (F31 DA030060). Matthew S. McMurray was supported in part by NIDA predoctoral training grant (F31 DA026251). [^1]: Edited by: Sheryl Moy, University

a mortgage. Nothing in the mortgage or note indicated that the corporation was acting as agent or nominee for the partnership. 6 A year later the corporation obtained $1,675,000 improvement financing from the United States National Bank of Omaha, executing a note, a mortgage, a financing statement, and an assignment of rents to the bank. Nothing in these documents or the bank's records indicated that the corporation was acting as agent for the partnership. The corporation also obtained title insurance on the property. 7 The corporation was also involved in several lawsuits as owner of the property. In February 1974, taxpayer, as attorney for the corporation, protested an adverse zoning ordinance and sought a variance. Three suppliers also sued the corporation. In none of these suitsAbout a third of children with an initial wheezing episode due to bronchiolitis will have recurrent episodes of wheezing.[@bib13] This association has prompted speculation that severe episodes of RSV bronchiolitis in infancy initiate the development of asthma. Sigurs and colleagues[@bib14] explored the association between an RSV infection sufficient to cause admission to hospital and the eventual development of asthma. Beginning in 1989, they identified 52 infants who were receiving treatment in hospital for RSV bronchiolitis and assessed their disease progression until they were 13 years old. The patients were matched with 93 healthy individuals of similar age and sex. When the children were 7·5 years old, those with a family history of both asthma and bronchiolitis had high rates of asthma (38%; 8 of 21 patients) compared with those

epidemics of asthma, which happen regularly in the northern hemisphere, and how these events might provide novel insights into both host and environmental factors that lead to asthma exacerbations. In Canada, the sharp increases in emergency department visits for acute asthma and admissions for childhood asthma have been predictable year-to-year. As these investigators point out, aeroallergens, air pollution, and interactions with climate can affect asthma exacerbations. To test the hypothesis that asthma exacerbations at the beginning of the school year were related to viral respiratory infections, these researchers assessed children presenting to an emergency department during 3 weeks in September along with community-recruited children with equally severe asthma who did not require acute care.[@bib62] For 62% (n=52) of the children with asthma visiting emergency departments, a respiratory virusLingyin Lingyin may refer to: Lingyin Temple, Buddhist temple in Hangzhou, Zhejiang, China Prime minister (Chu State), or lingyin, prime minister or chancellor of ancient Chinese state of Chu

gout was diagnosed with gouty arthritis based on recurring arthritis in the first MTP joint of the left foot for 9 years. He was treated with non-steroidal anti-inflammatory drugs (NSAIDs) during episodes, but he was not treated for hyperuricemia. He took 45 g of alcohol every day and had overconsumption of purine-rich foods. In May 2017, he presented with arthralgia in the first MTP joints of both feet and in the left ankle. Despite treatment with NSAIDs, arthralgia expanded to the right knee and the right ankle in July 2017. He was referred to our department in August 2017 for further evaluation of polyarthralgia with a high level of C-reactive protein (CRP) (6.85 mg/dL). On physical examination, His height was 175.5 cm and his weight was 67.4 kg. Body temperature was 36.5°C,President Bush, despite all of his speeches and press conferences about "victory" in Iraq, seems unable to break through one barrier. The problem isn't the American public's lack of confidence in U.S. forces. It's their lack of confidence in the Iraqis. In his Oval Office address to the nation on December 18, Bush hailed the recent Iraqi election as a milestone, "a landmark day in the history of liberty." American people seem to agree. In the ABC News/Washington Post poll taken just before the president's speech, 60 percent of respondents said the United States is making significant progress toward restoring civil order in Iraq. And 65 percent said the U.S. is making significant progress toward establishing democratic government there. But people seem to have a problem when Bush talks about

The latest fallout from the disappearance and presumptive murder of Saudi journalist Jamal Khashoggi could see the Saudis losing their main source of arms. Sen. Rand Paul (R-KY) says he intends to force a vote on blocking further US arms sales to the Saudi kingdom. Sen. Paul announced the plan on a local radio show, saying he hopes to force a vote in the Senate by the end of the week which would force a full halt to US arms shipments if there is “any indication” the Saudis are behind killing Khashoggi. The fate of the journalist, who has been critical of the Saudi crown prince, has been a subject of speculation over the past week, after he entered the Saudi consulate in Istanbul and was never seen again. HisIntroduction ============ Japan has achieved one of the longest lifespans in the world; in 2016, the average life expectancy was 87.14 years for women and 80.98 years for men (Ministry of Health, Labor, and Welfare 2017). The Japanese government is now trying to extend the "healthy" life expectancy, in which people can live healthy lives without support. The Japanese healthy life expectancy in 2016 was estimated to be 74.79 years for women and 72.14 years for men (Ministry of Health, Labor, and Welfare 2017). Three major causes of disruption of the healthy lives of Japanese people are (1) dementia, (2) cerebrovascular diseases, and (3) diseases of locomotive organs, including bone fractures and arthropathies (Comprehensive Survey of Living Conditions of 2016, Ministry of Health, Labor, and Welfare). To extend the healthy

measure the air velocity. The oscillatory engine was placed on top of the water surface inside the container. While the water temperature was varied from 16 °C to 31 °C, the oscillation frequency of shutters was recorded using a digital camera (Canon EOS Rebel T5i). During the experiment, the compression applied to the buckling beam was slightly adjusted to achieve the maximum oscillation rate for different water temperatures. Characterization of the rotary engine ------------------------------------- The five-disk rotary engine was placed in a closed chamber of 2-mm-thick acrylic glasses. A stream of humidity-controlled air was pumped into the chamber through plastic tubing. RH and temperature were measured both in the humid enclose of the rotary engine and in the surrounding environment. Humidity and temperature in the chamber was measured using Vaisala HMP77 Humidity andSonobuoy A sonobuoy (a portmanteau of sonar and buoy) is a relatively small buoy (typically , in diameter and long) expendable sonar system that is dropped/ejected from aircraft or ships conducting anti-submarine warfare or underwater acoustic research. Theory of operation Sonobuoys are ejected from aircraft in canisters and deploy upon water impact. An inflatable surface float with a radio transmitter remains on the surface for communication with the aircraft, while one or more hydrophone sensors and stabilizing equipment descend below the surface to a selected depth that is variable, depending on environmental conditions and the search pattern. The buoy relays acoustic information from its hydrophone(s) via UHF/VHF radio to operators on board the aircraft. History With the technological improvement of the submarine in modern warfare, the need for an effective

rallied to replace the motor in the No. 88 after an issue earlier in the weekend only to see Taylor forced to the pits after just 12 laps with clutch failure in the opening Group B race. The Rogers Motorsports No. 44 Jaguar XJR7 of Wallace, Smith and James Gue also saw an early end to its 2018 Classic Daytona as the car was retired in the second Group C round with a likely head gasket issue that was causing the car to overheat.Introduction ============ The rapidly expanding volume of medical knowledge on early-onset scoliosis (EOS) has led to a significant evolution in the understanding and management of EOS. EOS refers to a spinal deformity that is present before the age of 10 years, and it is categorized into five types according to the etiology: idiopathic, congenital, thoracogenic, neuromuscular, and syndromic.^\[[@R1]\]^ Because of the various etiologies of EOS, there is no standardized or widely accepted classification system. Based on the etiology, magnitude of the major curve, kyphosis and the annual rate of progression, a new classification of EOS was recently designed by 15 experienced pediatric spine surgeons.^\[[@R2]\]^ High levels of agreement and consistency of this classification have been reported.^\[[@R2],[@R3]\]^ The treatment goals for EOS include minimizing the spinal deformity while maximizing the thoracic volume and

are confined to mild to moderate deformity. Despite the strict indications and limited applications, the greatest advantage of VBT and VBS is that they can preserve the growth potential and mobility in the spinal segments. The major disadvantages of these two techniques include the pulmonary and bowel complications caused by anterior surgeries. ### Shilla growth guidance system (SGGS) The SGGS was first reported in 2014.^\[[@R53]\]^ SGGS guides spinal growth toward a normal alignment. The Shilla technique first corrects the apical deformity toward a neutral alignment. Then, the upper and lower growth guidance portions extend into the distal and proximal areas of the curve using polyaxial screws. These special screws have locking caps that fix to the top of the screws (not the rod) and capture the rod, allowing it toChopper scam case: Christian Michel's CBI custody extended by 5 days NEW DELHI: A Delhi court on Monday extended CBI custody of Chrishtian Michel, the alleged AgustaWestland middleman, by another 5 days. The court had earlier on December 5 remanded Michel in CBI custody for five days.During the hearing, the CBI told the court that Michel was not cooperating with the probe and was evasive in giving answers.At the outset, Michel withdrew his earlier bail plea and filed fresh detailed bail application.Michel was extradited from Dubai after clearance from the UAE government on December 4. He is one of the three middlemen being probed in the AgustaWestland chopper case, apart from Italian Guido Haschke (US and Italian nationality) and Carlo Gerosa (Swiss and Italian nationality).It was alleged that he

the NSS Space Settlement Journal. His space settlement work may be found at space.alglobus.net. This article originally appeared in Ad Astra, Spring, 2013. NSS is an independent nonprofit nonpartisan educational membership organization dedicated to the creation of a spacefaring civilization. Our vision: People living and working in thriving communities beyond the Earth, and using the vast resources of space for the dramatic betterment of humanity.Great Neck, NY; Northwestern University Institutional Review Board, Chicago, IL; NYU School of Medicine Institutional Review Board, New York, NY; Ochsner Institutional Review Board, New Orleans, LA; Rhode Island Hospital Institutional Review Board, Providence, RI; Saint Louis University Institutional Review Board, St. Louis, MO; Southern New Hampshire Medical Center Institutional Review Board, Nashua, NH; SUNY Downstate Institutional Review Board, Brooklyn, NY; UAB Institutional Review Board for Human Use, Birmingham, AL; University of California, Los Angeles Institutional Review Board, Los Angeles, CA; University of California, San Diego Institutional Review Board, San Diego, CA; University of Maryland, Baltimore Institutional Review Board, Baltimore, MD; University of Massachusetts Medical School Committee for the Protection of Human Subjects in Research, Worcester, MA; University of Rochester Research Subjects Review Board, Rochester, NY; University of

and NSF, United States of America. In addition, individual groups and members have received support from BCKDF, the Canada Council, CANARIE, CRC, Compute Canada, FQRNT, and the Ontario Innovation Trust, Canada; EPLANET, ERC, ERDF, FP7, Horizon 2020 and Marie Skłodowska-Curie Actions, European Union; Investissements d'Avenir Labex and Idex, ANR, Région Auvergne and Fondation Partager le Savoir, France; DFG and AvH Foundation, Germany; Herakleitos, Thales and Aristeia programmes co-financed by EU-ESF and the Greek NSRF; BSF, GIF and Minerva, Israel; BRF, Norway; CERCA Programme Generalitat de Catalunya, Generalitat Valenciana, Spain; the Royal Society and Leverhulme Trust, United Kingdom. The crucial computing support from all WLCG partners is acknowledged gratefully, in particular from CERN, the ATLAS Tier-1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAFwas an interesting speech. He is the “Craig” of Craigslist.org….one of the largest and most heavily trafficked sites on the planet (roughly 22 billion page views per month). Most CEO speeches I’ve seen say “Work as hard as you can and you might make it to the top” …something like that. However Craig ended up founder of one of the worlds largest websites through a slightly different…some would say “lucky” story. Directly from his speech: In 1994 he was doing IT for the financial firm Charles Schwab, nothing big. 1995 he started regularly sending out an email to about 12 of his friends with a bunch of events around the San Francisco Bay Area. His friends would forward the email to their friends, and then their friends etc… Eventually he had 100+ people on

IHR 2005 requires states meet a burden of proof to justify economic restrictions. The Second Emergency: 2009 H1N1 Influenza Pandemic {#Sec4} ================================================== The 2009 H1N1 influenza pandemic was the first global pandemic since 1968.[@CR15] Fortunately the virus proved less virulent than originally thought[@CR16] and provided an important illustration of IHR 2005 in practice. The 2009 H1N1 influenza outbreak emerged in Mexico, then spread further into North America and to most countries worldwide. Mexico responded aggressively, instituting broad community mitigation strategies: closure of public places and businesses, and education about sanitation measures, quarantine, and isolation.[@CR17] During the spring of 2009, significant social and economic disruption caused trade losses estimated at more than \$2.3 billion.[@CR17] International health experts found that Mexico acted quickly, proactively, and with transparency.[@CR18] Yet legal and academic public health commentatorsclear-cut method. Over time, clear-cut logging has been used for a variety of reasons. They include, but are not limited to, generating revenue, the maximum production of wood fiber for its many uses, and clearing land for houses and businesses. Clear-cut logging possesses some positive outcomes and some negative outcomes. The positives of clear-cut logging include: The increased amount of jobs available, which in turn betters America’s economy by generating revenue, the chance for prevention of catastrophic fires, and the bettering of forest health. Another benefit is the production of wood products, and the access provided to the public from the logging roads. On the other hand, the negatives of clear-cut logging include the increased amount of sedimentation in streams and rivers, the increase in water temperatures, the degradation of

China Plain in the summer maize growing seasons of 2012 and 2013. The study field is located in a warm, semihumid region with a continental climate. The average annual rainfall is 786.3 mm, and 65.1% of the local rainfall is concentrated in the summer, which can satisfy the water requirement for all growth stages of summer maize. The soil of the experimental site is loamy (40% sand, 44% silt, and 16% clay) with 32.4% field water capacity \[[@B26]\]. In the 2012 and 2013 summer maize growing seasons, total rainfall was 337.1 and 461.8 mm, respectively. The experiment was conducted in plots divided by concrete walls that were 25 cm thick and that extend 1.5 m beneath the surface. The area of the plots was 3 m × 3 m. Visual observations of the experimentalto the neck, the sleeve-on-bag portion of the SBoV hangs freely from the neck and into the container interior. The SBoV is then filled under pressure through the valve with fluid composition. The art recognizes the need for alternate ways to secure the SBoV assembly to the support container, and, in particular, SBoV installment that avoids insertion through the top opening of the support container.

conduct in part to the confusion and fear resulting from the events at the nightclub, where he was yelled at and punched to the ground. Volpe was also reportedly feeling the stress of being a police officer in an inner city precinct. But however frightened and angry he was, Volpe's response was wildly out of proportion to the pressures upon him. Volpe also says his overall psychological and emotional condition added to these immediate pressures. At defense counsel's request, Dr. N.G. Berrill, a psychologist, interviewed Volpe and provided a psychological profile to the Probation Department. Dr. Berrill found that Volpe was "vulnerable to becoming overly influenced by [intense] emotions" and to poor decision making "at times of significant external stress." He concluded that the "principal catalyst" for Volpe's criminalresection of the two-hazelnut-sized myxoma at the posterior wall of the left atrium was performed again. The operation and inpatient course again proceeded without complications and the patient was rapidly discharged again. After a period of four years an echopenic structure with freely moving component parts was found at the left side during a transesophageal echocardiography and the suspicion of a second relapse was raised. Making additionally there were found sutures of the previous operations at the septum. But making a clear differentiation between a thrombus at the previous suture line and a myxoma relapse was not possible; therefore a three months oral anticoagulation with phenprocoumon was started. With a positive family history for myxomas (the patients\'s brother and grandfather) and multiple lentigines an evaluation of the presence of Carney

In the heart of Chicago city centre, and within walking distance to major attractions, this all-suite hotel provides exceptional accommodation, complete with first-class amenities and personalized services. The on-site Local Chicago Restaurant puts a unique spin on traditional dishes by adding local Chicago flair. Try the Scottish salmon Reuben. Or go to Mirai Sushi Gold Coast, which serves dishes with a twist on traditional Japanese cuisine. Enjoy a restful nights sleep on the Magnificent Mile Hilton's signature Sweet Dreams bed or take advantage of breathtaking views from the rooftop pool and fitness centre. Take a short stroll to the nearby John Hancock Center or beautiful Lakeshore Drive, both located only seconds from the Hilton Suites Chicago/Magnificent Mile. The Museum of Contemporary Art, Navy Pier and the gourmet restaurants and exciting nightlifewith diverse specialists including epidemiologists, clinicians, veterinarians, and microbiologists, and are thus in an excellent position to discover emerging infectious diseases ([@b2-121-126]). Pathology has played a critical role in advancing the knowledge of emerging infectious diseases ([@b3-121-126]). Hantavirus at the Four Corners ------------------------------ For example, in 1993, an unexplained respiratory illness appeared in the Four Corners area (a region of the United States where the boundaries of Colorado, New Mexico, Arizona, and Utah meet) with reports of a influenza-like illness with high mortality rates in previously healthy young adults. The diligence of forensic pathologists in New Mexico in pursuing and performing autopsies was invaluable to the investigation ([@b4-121-126]). These autopsies revealed pulmonary edema and large proteinaceous pleural effusions. At the first meeting of the three joint investigators (the New Mexico Department

of Health, the Office of the Medical Investigator at the University of New Mexico School of Medicine, and CDC) a list was established of the most likely causes (i.e., influenza, plague, or a possible new agent) and intensive diagnostic efforts were mounted. The first breakthrough came via serologic testing at CDC with the detection of hantaviral antibodies in serum of patients who had succumbed to the illness ([@b5-121-126]). This was an unexpected finding because, at that time, there was no known pathogenic hantavirus in the United States, and all characterized pathogenic hantaviruses in other parts of the world caused renal disease with hemorrhage, unlike the pulmonary nonhemorrhagic disease observed in the Four Corners patients. Proof that this illness was caused by a hantavirus arrived rapidly through two hantavirus-specific testsbeen identified in the United States; today, 24 hantaviruses with differing levels of pathogenicity have been identified in the Americas. This recognition of New World hantaviruses, coupled with a better understanding of hantavirus pulmonary syndrome, has resulted in critical improvements in the rapid recognition and clinical management of the disease and better understanding of the natural reservoir (rodents) and mode of transmission, all of which have greatly improved the ability to implement control and prevention measures, with emphasis on the critical role of individual communities. Leptospirosis in Nicaragua -------------------------- In 1995, another pulmonary outbreak was reported, this time in Nicaragua, with several hundred cases and many deaths. An important difference with this outbreak was that instead of the clear fluid usually observed accumulating in the lungs, frank hemorrhage was detected ([@b8-121-126]).

appropriate medical or social service providers in the community, if available, but received none of the on-site, enhanced services or treatments funded by the PCPPP. Ethical approval to conduct the study was granted by the Institutional Review Board of Drexel University, Philadelphia Department of public Health, and the University of Pennsylvania. A total of 471 women in the intervention group received at least one complete follow-up clinical assessment, and it is those women who comprise the analytical sample for the findings presented here. Based on a preliminary analyses of survey data collected at the time of enrollment we found that women assigned to the intervention group but who were lost to follow up after enrollment (n = 94) were not significantly or substantively different from the 471 women in the studyA systematic review of the literature by Gavin and colleagues revealed that, approximately 19 percent of new mothers suffer from some form of depression at some point during the first three months following delivery, and as many as 7 percent have been diagnosed as having suffered from major depression \[[@CR24]\]. In the PCPPP study a total of 471 women in the intervention group were screened for depressive symptomatology during the first 3 months postpartum; of those 237 or 29 percent were identified as being "possibly depressed" according to the Center for Epidemiological Studies of Depression Scale (CES-D). Subsequent evaluation of the "possibly depressed" group using the SCID revealed that 16 percent of the intervention group was clinically depressed, more than twice the equivalent period prevalence rate reported by Gavin

1997 letter, his filings and oral argument before this court imply nothing other than the fact that he received it shortly after its stated mailing date of January 21, 1997. 13 rejected it with respect to the September 24, 1996 letter. Battle's receipt of the January 21, 1997 letter and the fact that the cover page of Battle's SFIP listed SCIC as a subsidiary company of "THE SEI- BELS BRUCE INSURANCE COMPANIES," at a minimum, gave Battle sufficient facts about the alleged harm done toreached after three attempts of visiting their home. In total 52% of the Turkish sample participated in the study, which resulted in 519 participants. Of the Moroccan sample 601 persons were contacted at their home address. Of these persons 30% refused to participate in the study and 23% was not reached after three attempts. In total 46% of the Moroccan sample participated in the study which resulted in 277 participants. Due to many missing or invalid data (15%) on weight and height, the total numbers of participants used in our analyses were 249 Moroccan and 424 Turkish men and women. The study sample appeared to be representative of the Turkish and Moroccan populations (aged 15-30 years) living in Amsterdam and according to sex, generational status, city district and educational

first generation women, more Turkish than Moroccan women were represented. Among men there were no differences between the generations with regard to ethnic background. Approximately two-thirds of the first generation group had migrated to the Netherlands after the age of 6 years. In women, we found more significant generational differences in socioeconomic position than in men, with second generation women being higher educated than first generation women. Among women, the first generation had migrated more often for reasons of marriage or family reunions, while (the family of) the second generation had mostly migrated for economic reasons (education or employment). No generational differences were found in men for the reason of migration. For both men and women the cultural and religious factors generally differed between the generations with lowerWhat was Barack Obama's #FirstTweet? It came when he was still a senator from Illinois:Thinking we're only one signature away from ending the war in Iraq. Learn more at http://www.barackobama.com— Barack Obama (@BarackObama) April 29, 2007Obama was already running for president and was was leading the charge to end the Iraq War, which became a campaign issue in the '08 election and remained a challenge throughout his presidency. We looked up his first tweet because Twitter, which celebrated its eight anniversary on Thursday, is having …

small-screen favorite. Michael K. Williams, a.k.a. Omar Little on The Wire, has just boarded the cast, which also includes Chiwetel Ejiofor, Michael Fassbender, and Brad Pitt. More details after the jump. UPDATE: A few hours after this post went up, it was announced that Beasts of the Southern Wild star Dwight Henry had also joined Twelve Years a Slave. With Cannes just around the corner we’re going to start seeing even more clips and trailer from some of our most anticipated movies of the year. One of the big ones is Killing Them Softly, the third feature film from Andrew Dominik (Chopper, The Assassination of Jesse James by the Coward Robert Ford) that was formerly titled Cogan’s Trade. We haven’t seen any footage at all from this one yet, somore than 80 km distance between the farms where Cases 1 and 3 occurred. There was over 300 km distance between the location of Case 2 and the other two farms. There was no known contact between any of the horses and personnel on any of the farms. *Case 1* was a thoroughbred filly, aged 15 months residing in the Hunter Valley in NSW Australia, that presented in November 2012 with progressive lameness in the right foreleg of 2 weeks\' duration. On arrival the horse was bright and alert, severely lame in the right foreleg and, apart from being febrile (38.9°C), had normal vital signs and no other identified focus of infection. There was swelling and obvious pain on direct palpation of the right fore shoulder region, including the bicipital bursa.

of this horse have been multiple stakes winners. *Case 2* was a thoroughbred filly aged 7 months, residing in the Southern Highlands district of NSW that presented in August 2013 with lameness in the left foreleg, of uncertain duration. Despite treatment for 72 hours with doxycycline, lameness progressed and the horse was referred for further evaluation and possible surgery. On arrival the horse was bright and alert, severely lame at the walk in the left foreleg, afebrile with normal vital signs and no other identified focus of infection. There was swelling and severe pain on palpation of the proximal axial aspect of the medial splint bone. Radiographic projections showed evidence of a focal area of cortical bone resorption in the palmaromedial mid-proximal diaphyseal cortex of the left third metacarpalhops added on day 8. On day 12 beer was transferred to a co2 purged keg, seal added, and keg was purged again (multiple times). FG 1.005. Pressure was set to 30psi, shaken lightly and left in kegerator for 24 hours, pressure then reduced to serving. Brewed – June 13th First Dry Hop addition – June 17th Second Dry Hop addition – June 21st Kegged – June 25th Appearance: Pours with a white head, half finger, and fades to quarter finger within a few minutes before fading to a thin ring eventually. Golden in color, and lightly hazy. Aroma: Over ripe, and tropical fruit followed by some mild Brett funk. Taste: Moderate fruit, and tropical hop flavors, mostly pineapple, and mango. Mid taste Brett makes its presence known, but never over takes the hops, light

minority groups, and about half were the first in their families to attend university. As such, many BUSP alumni lacked at least some of the skills, knowledge and dispositions their middle-class/majority counterparts frequently took for granted---in particular, college-educated parents who could act as informational resources for students planning academic careers. As one former director said:"There's just a lot of savvy, if you like, that students who are from college-going backgrounds, college-going families, have that's just been transmitted \[from their parents\] that students who aren't from those backgrounds don't have.-Gina Holland, Former Director, BUSP"Recognizing how this deficiency in "savvy" can put minority students at a disadvantage, one major goal of BUSP was to provide advisors who could help students navigate this unfamiliar institutional context. In their first year, BUSPparents"---hovering over students to make sure they were ready for each step along their academic journey. In some instances, advisors were able to offer culturally sensitive advice to help minority students surmount motivational roadblocks---providing confidence that "someone like me" can succeed in the university setting. Moreover, these advising strategies not only helped students realize the range of available career options, but also worked to align their aspirations in ways that increased the likelihood for their overall academic and career success. Factor Two: Social Capital and an Alternative Intellectual Community {#Sec14} -------------------------------------------------------------------- The second factor alumni identified as especially salient to their academic and career success was ready and immediate access to a community of like-minded peers. While "peer climate" and contexts have shown promise in explaining students' persistence to degree completion,

Systems Inc., Paramus, NJ, USA) was performed at the baseline visit. A course of injections included three injections given 4 weeks apart and was followed by a doctor's review with an OCT scan 4 weeks after the third injection. A repeat course of injections was given if the patient had any clinical/OCT evidence of DME. During the study period, four eyes received panretinal laser photocoagulation and one eye underwent cataract surgery. The study period ended at the last follow-up or at the time of eyes subsequently receiving other intravitreal therapies or macula laser for DME, whichever was sooner. We classified anatomical responders as those with evidence of a central macula thickness (CMT) reduction of ≥20% after the first course of three injections, in line with previous studies of anti-VEGF intravitrealsealed the fate of the game. The Bruins tied the score at the 76th minute when Ally Courtnall, who carried down the right and cut inside, unleashed a left-footed shot over Stanford goalkeeper Jane Campbell, who had a total of five saves. Courtnall was assisted by Annie Alvarado and Darian Jenkins. The Cardinal fell behind when Annie Alvarado, with an assist from Sam Mewis, scored on a low cross-goal shot from about 10 yards from the right. The ball snuck inside the left post at the 84th minute. It was the first loss for the Card this season and also the first time that the team has trailed at any point in a game. With the win, UCLA stands alone as first place in the conference over the Cardinal. Stanford

explore the views of professional stakeholders on how health services, in particular primary care, can support carers and scope for strengthening such support in England. 2. METHODS {#hsc12898-sec-0005} ========== In this scoping study, qualitative semi‐structured interviews were conducted with professional stakeholders (policy makers, commissioners, front line clinicians, LA staff and voluntary sector organisations) between December 2016 and March 2017. The Central University Research Ethics Committee, University of Oxford, classified this project as a pre‐research activity (2 November 2016) and advised that no formal ethical approval was necessary. A scoping review was conducted on health and care policy specific to carers, and research on carer needs, outcomes and support from services. The semi‐structured topic guide was developed by the authors on the basis of this review and their expertise on carer research. Theof the network of the researchers) or with publicly available contact details were contacted via email. The intention was to recruit a mixed, but pragmatic, sample of policy makers, commissioners, front line clinicians, LA staff and voluntary sector organisations. A total of 54 stakeholders were contacted; no response was received from 19, nine responded that they were unable to participate (usually due to time constraints) and one email was undeliverable. The majority of invited stakeholders were front line clinicians (predominantly GPs, but also nurses or some specialist doctors) from different parts of the England. A wide range of Voluntary Sector Organisations were contacted, including some generic (such as Age UK) and some disease specific (such as Macmillan Cancer, the mental health charity MIND). Local carer organisations across England were

an ice hockey player based on the league in which he plays (e.g. first league, second league, etc.) and by his participation in national competitions (Ice hockey Extraleague (ELH), Russian continental league (KHL), Canadian-American National Hockey League (NHL) and others). The aim of our study was to compare the somatic variables of players in the Russian KHL and those of the top Czech ice hockey league, the ELH, who regularly participate in playoff games. The variables of the KHL players can be considered representative of ice hockey players, since the KHL is regarded by professionals to be the second-best ice hockey league in the world, after the Canadian-American National Hockey League. Therefore, we believe that our findings will allow us to assess the effect of somatic variables onsports performance of professional ice hockey players. In addition to the goaltender, there are 2 positions in ice hockey, the forward and defenseman. A secondary aim of this study was to compare the variables of the players based on their position in the game to determine if it affects somatic characteristics. This information may aid coaches in the selection of players with characteristics appropriate for a particular position and also for the development of training protocols specific to the position. The aim of this study was to evaluate basic morphological variables of contemporary elite ice hockey players and to compare the variables of KHL players with those of ELH players. The secondary aim was to compare the monitored variables with regard to the game position of the players. Material and Methods ==================== Participants ------------ The

KHL players. The practical significance of those variables was also confirmed: it was high for BF (kg) and intermediate for FFM (kg). As for the other parameters, no statistically significant differences were observed. Segmental analysis of the ELH and KHL forwards revealed that fat was evenly distributed on the right and left extremities, with slightly more fat on lower extremities. There were no statistically or practically significant differences in fat distribution among individual segments, although the ELH forwards had more fat on their trunks (2.09 %). The BM, BMI, FFMI, and FFM of the ELH defensemen were significantly lower than the values for the KHL defensemen. The practical significance of the BMI and FFMI of the defensemen was high, intermediate for FFM and low for BM. The significantly higher BMIof the country. We are fiercely proud of our state and culture, but we feel like Woody on his first day at Cheers when compared with New York or L.A. So when the biggest icon in football thanked us from the bottom of his heart that day in March 2012, it was personal. It was the dissolution of a covenant Manning had made with each fan individually. We cheered. He worked. We defended him. He prepared. We celebrated. He won. Before Peyton Manning arrived, the Indianapolis Colts were 50-62 in home games from 1984-1997. During his tenure as quarterback, they went 76-28. That’s a lot of happy Sundays in the Circle City. He kept his end of the bargain. He won so often in Indianapolis that we built a bigger stadium so

3 A-3452-17T2 percent of the lot. Accordingly, OZ sought relief from the minimum lot area, minimum lot depth, and minimum rear yard requirements. At the hearing, OZ's counsel explained that the variances OZ sought to construct the three-family home had been approved by the Planning Board in 2007, but at that time, OZ failedHuman2.5M Beadchip (2,443,179 markers). The clinical features of our GWAS cohort were documented on the basis of standard ACR classification criteria. The experiment was designed to avoid batch effects to the greatest extent possible. All DNA samples were sent to the laboratory at King's College London, UK, where the integrity of the DNA was checked. The GWAS samples were then genotyped at a single laboratory. All data analysis was carried out in the laboratory at King's College. Genotyping for the GWAS was carried out using 82 plates, processed in 13 batches. Duplicate samples taken from HapMap Phase 3 were added to each plate to check genotyping quality. Case-control status and country of recruitment were randomized across plates as far as possible, in order to avoid artifactual differences in genotyping between

by the China Scholarship Council, number 201406380127. The research was funded/supported by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Guy\'s and St Thomas\' NHS Foundation Trust and King\'s College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. The Health and Retirement Study genetic data were obtained from dbGaP under accession phs000187.v1; the study is sponsored by the National Institute on Aging (grant numbers U01AG009740, RC2AG036495, and RC4AG039029) and was conducted by the University of Michigan. The melanoma study data were obtained from dbGaP under accession number phs000187.v1.p1. Research support to collect data and develop an application to support this project was provided by 3P50CA093459, 5P50CA097007, 5R01ES011740, and 5R01CA133996. FundingCenter, Dutch and Polish samples). *Spain*: Josefina Cortés Hernández, Josep Ordi Ros, Jesús Castro Marrero (Vall d'Hebron Research Institute). *Turkey:* Sule Yavuz (Istanbul Bilim University, Avrupa Florence Nightingale Hospital). *UK*: Caroline Gordon (University of Birmingham), Katie Vinen (King's College London), David Isenberg (University College Hospital), Lars Erwig (University of Aberdeen), David D'Cruz (St Thomas' Hospital, London), AJ Rees (MRC/KRUK GN Biobank), Ian Bruce (University of Manchester). *USA*: Amr Sawalha (University of Michigan, Turkish samples), Lindsey Criswell (UCSF). For the replication study, samples were provided by Joan Wither (Toronto Western Research Institute, University Health Network, Canada), Earl Silverman (The Hospital for Sick Children and University of Toronto, Canada), Pat Gaffney (Oklahoma Medical Research Foundation, USA), Ann-Christine Syvänen, Lars Rönnblom (Uppsala Universitet, Sweden), Reinhard Voll, Georg Schett, Barbara Fuernrohr (University of

and The Bunnymen. It was a venue I passed very regularly as a student and always dreamed of going in, and the first time I did was walking onto the stage to play!" It looks like Liam McClair has an eventful 2018 lined up, with a single recorded and another EP in the pipeline. Fans can also expect more shows to follow later this year. In the meantime, catch him at The Eagle for an exclusive, live performance free of charge.and he introduced six methodological steps as a practical approach to the hermeneutic phenomenology ([@A25158R17]). The first step refers to the researcher's interest in the phenomenon, and in this case, the researcher was interested in understanding the challenges of patients living with an ICD when he was working as a clinical nurse. The second step was the selection of study participants who exhibited the challenges of living with an ICD. The participants were purposefully selected with maximum variation sampling from those patients referred to the cardiac clinic of the governmental Imam Khomeini hospital in Tehran, Iran in 2013. Seven men and six women participated in this study, and the inclusion criteria were the willingness of the patients to participate in the research and talk about their experiences. Those

the text of each interview as a whole, wrote their perceptions of the life challenges, and the text was read frequently with a selective approach. Those sentences, phrases, and words which seemed relevant to the challenges of living with an ICD were selected; then, the same phrases and sentences were transformed to become the meaningful units. The units obtained from each interview were written on a separate sheet, and the semantic similarities and differences were placed in a separate column. The researcher achieved more general terms with the integration of semantic units. The fourth step of Van Manen was the art of writing and rewriting. At this stage, the researcher extracted the essential themes of the interviews and wrote them several times to determine a strong description of theauthor). This manuscript has been extracted from research project "The experiences of living with implantable defibrillator" approved by the Nursing and Midwifery Care Research Center, Tehran University of Medical Sciences (2011, project Code: 14655-99-03-90) which was conducted with financial support of Tehran University of Medical Sciences. The authors would like to thank the deputy of the Tehran University of Medical Sciences, Dr. Mollahzadeh (cardiologist at Imam Khomeini Hospital), and all of the participants and personnel of the center for Nursing Care Research, Tehran University of Medical Sciences. **Authors' Contribution:**Mohammad Abbasi designed the study, performed the data collection and data analysis, and was responsible for drafting the manuscript. Reza Negarandeh supervised all stages of the study and was the corresponding author. Reza Norouzadeh made critical revisions to the paper and submitted

trio misused Aadhaar details of other people to obtain their pension money granted under the Aasara scheme. The issue came to light after one Chavan Dashrath, resident of Rajannabowli in Falaknuma, lodged a complaint on Thursday, stating his 12-digit UID was misused to swindle his pension money. On enquiry, police found that Aziz and associates had downloaded Aadhaar numbers from the internet and used it to open separate bank accounts through an SBI kiosk in Edi Bazaar. Police estimate that 300 such fraudulent accounts were created with ficticious names and addresses by the accused to swindle money. The accused then posed as persons authorised to process the Asara Pension Health Scheme for senior citizens at the Bandlaguda Tahsildar Officer and collected money from the government on the pretext ofTokyo, Japan). The southern coastal region has been particularly urbanized. The study area, which has an average population density of 1,206 people per square kilometer, is adjacent to the second largest metropolitan area in Japan (Osaka) on the east. Generally, agricultural ponds are constructed by banking up streams or spring water. For that reason, each pond has an original catchment upstream. The pond water resource depends fundamentally on rainwater that the catchment receives. After the late 1940s, however, massive water resource development projects including dams and canals changed irrigation systems and diversified the ponds\' water resources. Now, reservoir and river water are supplied to ponds as necessary via canal networks with main canals of approximately 3 m width and 2 m depth [@pone.0099709-Land1]. In the study area, eight agricultural

has best represented behavioral characteristics of human related to the stocking of invasive fish species. In urban areas, although ponds are surrounded by denser road networks, visibility is apparently reduced by the many blocks of buildings that obscure the ponds. Consequently, the classification tree using only road density showed overestimation of the presence for Bluegill. In contrast to visibility and road density, the urban ratio was not adopted for any classification tree as a predictor in our analyses. Sport anglers are generally known to come not from the immediate proximity of the ponds but from more populated urban areas such as southern coastal regions and metropolitan areas on the eastern edge of the study area. At a local scale with the study area of approximately 30 × 30 km,Saturday, December 22, 2012 Eggs and Corned Beef Hash - Brookside Diner, Whippany NJ The classic diner breakfast is an integral part of the local culture in the state of New Jersey. New Jersey has more diners per capita than any other place on the planet- and just about all of them take special pride in their breakfast offerings. It had been a while since I've been to any of the Garden State's many diners. My travels took me back to an area near where I once worked, so I took the opportunity to stop and have a little breakfast at one of the places I used to eat at from time to time- the Brookside Diner in Whippany, New Jersey. What I consider to be the classic Jersey Diner breakfast

goals in 69 appearances for Scotland. Miller retired from international football soon after the England match, with Scotland manager Gordon Strachan stating that Miller wanted to prolong his club career. Coaching career Upon signing a contract extension with Rangers in November 2016, Miller took up a part-time coaching role with their Under-20 team. After leaving Rangers in 2018, Miller had a short stint as player/manager of Livingston. He then continued his playing career with Dundee and Partick Thistle. Miller retired as a player in February 2020 and took a coaching role with Australian club Newcastle Jets. Career statistics Club International appearances International goals Scores and results list Scotland's goal tally first Manager Honours Club Wolverhampton Wanderers English First Division play-off winners: 2002–03 Celtic Scottish Premier League: 2006–07 Scottish Cup: 2006–07 Rangers Scottish Premier League: (3) 2008–09, 2009–10, 2010–11 Scottishin 454 GS-FLX sequence alignment, and drafted the manuscript. SG participated in 454 GS-FLX sequence alignment. PE collected viral isolates from the field, carried out the immunoassays, and participated in the design of the study. DL participated in the design of the immunoassays. CJK oversaw the 454 GS-FLX sequencing. CRB conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors have read and approved the final manuscript. Acknowledgements ================ This work was supported by Discovery Grants (Natural Science and Engineering Research Council (NSERC) of Canada) to CRB, CJK, and DL. EAM is the recipient of a NSERC postgraduate scholarship and past recipient of a NSERC Undergraduate Research Award.

equal to the postoperative cylinder. The surgically induced astigmatism (SIA) was defined as the vector difference between the preoperative cylinder and postoperative cylinder as the actual correction achieved. The index of success (IOS) was calculated by the magnitude of DV over the magnitude of TIA, which indicated that the residual astigmatism still existed (IOS = \|DV\|/\|TIA\|). The correction index (CI) was given as the proportion of the magnitude of SIA and TIA that showed that the intended correction was not successfully treated (CI = \|SIA\|/\|TIA\|). The angle of error (AofE) was measured in the half angular between the SIA and TIA vectors, which indicated whether the treatment was applied at correct axis. The magnitude of error (MofE) was defined as the arithmetic difference between the magnitude of the TIA and the SIAUkraine, rebels hold fresh peace talks as fighting rages in east MINSK/KIEV (Reuters) - Ukrainian and Russian representatives and separatist envoys met in a new round of peace talks on Saturday as fighting between Kiev’s forces and the Russian-backed rebels raged on in Ukraine’s east, claiming more civilian and military lives. The main members of the so-called contact group - Ukrainian former president Leonid Kuchma, a Russian diplomat and an Organization for Security and Cooperation in Europe official - met at a state residence in the Belarussian capital Minsk, where they were joined by two separatist officials. The sides have held only one inconclusive meeting since agreeing a ceasefire last September as part of a 12-point blueprint for peace. Much-violated from the start, that truce collapsed completely with a new rebel

Castro (PAHO/WHO Pan American Health Organization / World Health Organization, Brazil), Guy de Roy (Ordre des Medecins Conseil National, Belgium), Tony Delamothe (BMJ, United Kingdom), Martin D. Denz (Swiss Medical Informatics Association / Universitätsspital Zürich, Switzerland), Persephone Doupi (Erasmus University, Netherlands), Joan Dzenowagis (WHO World Health Organization, Switzerland), Christer Edling (The Swedish Society of Medicine, Sweden), Gunther Eysenbach (University of Heidelberg / MedCERTAIN, Germany), Gerard Freriks (TNO, Netherlands), Franz Frühwald (Internationales Büro der Österreichischen Ärztekammer, Austria), Lisa Gray (BIOME, United Kingdom), Pelle Gustafsson (Swedish Medical Association, Sweden), Gerhard Heine (European Commission, Luxembourg), Katrin Hörner (Arztpartner / Almeda, Germany), Robert Hsiung (University of Chicago, U.S.A.), Jostein Ingulfsen (Norwegian Board of Health, Norway), Thomas Isenberg (German Association of Consumer Organisations - Arbeitsgemeinschaft der Verbraucherverbände, Germany), Edward Jacob (KNMG, Netherlands), AlexR. Jadad (Canadian Cochrane Centre, Canada), Jacobo Kelber (ensalud.net, Mexico), Hugo Kitzinger (mymedia GmbH, Germany), Inge Kokot (Deutsches Grünes Kreuz e.V., Germany), Hans-Joachim Koubenec (Stiftung Warentest, Germany), Michel Labrecque (Université Laval Québec, Canada, Canada), Kristian Lampe (Finnish Office for Health Technology Assessment / MedCERTAIN, Finland), Stephane Lejeune (Swiss Cancer League, Switzerland), Leonard B. Lerer (INSEAD, France), Odile Leroy (PasteurMed, France), Nicolas Lienert (Medgate AG, Switzerland), Pål Lindström (LocusMedicus, Sweden), Sándor Lipp (Hungarian Ministry of Health, Hungary), Leena Lodenius (Finnish Duodecim Medical Society, Finland), Antti Malmivaara (Finnish Institute of Occupational Health, Finland), Miquel Angela Mayer Pujadas (Official Medical College of Barcelona, Spain), Peter Mills (EncycloMedica Ltd, United Kingdom), Cesar Molinero (Planet Medica, Belgium), Marc Muret (Zürcher Aerzte für Klassische Homöopathie, Switzerland), Wolfgang Nagel (GesundheitScout24 GmbH, Germany), Tim Nater (Health

on the Net Foundation HON, Switzerland), Joerg Nitzsche (Zentralbibiliothek für Medizin Koeln, Germany), Debra O´Connor (Cochrane Consumer & Communication Group, La Trobe University, Australia), Gert Purkert (Arztpartner / Almeda, Germany), Ramon Sarrias Ramis (Official Medical College of Barcelona, Spain), Christine Reuter (A MedWorld AG, Germany), Ahmad Risk (Internet Healthcare Coalition, United Kingdom), Carl Bénédict Roth (GetWellness, Switzerland), Sebastian Schmid (Arztpartner / Almeda, Germany), Christiane Schmitz (Heinrich Heine Universität, Germany), Luk Schoonbaert (Belgacom Multimedia Ventures, Belgium), Frank Schuler (gfp Kommunikation Köln, Germany), Ulrich Schwanke (DocCheck, Germany), Sasha Shepperd (Imperial College School of Medicine, United Kingdom), Myra Sidrassi (MedCERTAIN, Germany), Chris Sigouin (McMaster University, Canada), Chris Silagy (Monash Medical Centre, Australia), Denise Silber (Internet Healthcare Coalition, U.S.A), Martin Sonderegger (Universitätsspital Zürich, Switzerland), Anke Steckelberg (Universität Hamburg, Germany), Frederik Tautz (HeinrichHeine Universität, Germany), Nicolas P. Terry (Center for Health Law Studies, St. Louis University, U.S.A.), Christian Thomeczek (Ärztliche Zentralstelle Qualitätssicherung, Germany), Wouter Tukker, (Praha Communications, Czech Republic), Gerard H. van der Zanden (The Netherlands Institute for Health Promotion and Disease Prevention NIGZ, Netherlands), Georg von Below (Swiss Medical Assoc./FMH, Switzerland), Frank von Danwitz (Deutsches Diabetes-Forschungsinstitut, Germany), C.-Peter Waegemann (Medical Records Institute, U.S.A.), Thomas Wetter (Dept. Of Medical Informatics, Universität Heidelberg, Germany), Petra Wilson, (European Commission, Belgium), Margaret A. Winker (JAMA, U.S.A.), Jeremy Wyatt (University College London, United Kingdom), Gabriel Yihune (MedCERTAIN, Germany)

PLUMMETED: The box-office take on "The Thin Red Line," after Terence Malick's $52 million WWII semi-epic received its seven Academy Award nominations. The 50% plunge from the previous weekend is confounding movie analysts -- much as the movie seems to be confounding audiences.nerve bilaterally and the recurrent laryngeal nerve on the right side (The left stump of the recurrent laryngeal nerve had been irrecoverably lost in previous surgical attempts). In 2001, the working group published a follow-up on the first 40 months after the transplantation. An incipient immunological rejection reaction was brought under control by changing the immunosuppressant medication. The patient first reported sensations in the area of the larynx three months after the transplantation and eventually developed the ability to feed himself transorally. In the assessment of the treating physicians, vocal function improvement continued for 16 months after the transplantation. EMG revealed signs of reinnervation of the cricothyreoid muscle and the vocalis muscle. It did not prove feasible to achieve opening movements of the vocal cords sufficient for respiration by

representative proof. The difference in the distance between the ends of individual fibers and the drum surface also affects image density because of the fact that the end of the fiber bundle is flat while the surface of the drum is curved. Temperature variations in the print-head due to the ambient temperature of the machine as well as the fact that the writing process itself heats the print-head also influence the image density. Variations in the print medium elements, such as variations in the thickness of the donor and receiver elements as well as the various layers that are a part thereof, can also affect the image density as it is being written. Thus, it has been found necessary to provide a writing apparatus which meets all of the foregoingSevere acute respiratory syndrome (SARS) was first recognized in late February 2003 in Hanoi, Vietnam \[[@ref1]\]. Shortly thereafter, an outbreak of SARS occurred in Hong Kong, People\'s Republic of China, and 22% of the patients were health care workers (HCWs) in Hong Kong hospitals \[[@ref2]\]. At Prince of Wales Hospital, a 1350-bed teaching hospital in Hong Kong, the first wave of SARS-associated coronavirus (SARS-CoV) infection affected close to 80% of the staff on the medical ward. Within the first 2 weeks of this outbreak, which began on 10 March 2003, 69 HCWs were admitted for probable or suspected SARS \[[@ref3]\]. Isolation wards for probable and suspected SARS cases were established, and infection-control measures involving droplet precautions was implemented \[[@ref4]\]. In the next few weeks, 444 patients with probable SARS

upper limb of the patient was fixed using two straps, one at the forearm and one around the wrist and magnets fixed the fingertips to the actuators of a mechatronic hand orthosis (Tyromotion Amadeo HTS, Graz, Austria). This device was controlled by a BCI and moved the fingers of the paralyzed hand between an opened and a closed position. The range of the movement was adjusted in each session (Ramos-Murguialday et al., [@B26]) because it was limited by the spasticity of the patient. Each trial of the task consisted of three phases: preparation (2 s), feedback (6 s), and rest (8 s). During preparation, the subject received an auditory cue ("Left Hand") but was instructed to wait with the execution until the next auditory command ("Go!") was givenForbes columnist Steven Salzberg and author-investigator Joe Nickell will each be awarded the 2012 Robert P. Balles Prize in Critical Thinking, to be presented by the Committee for Skeptical Inquiry at the CFI Summit in October. From the Edge of Postcards: The Wem Ghost Photo Following a fire in a small English town, a mysterious photo of the blaze-seemingly depicting a girl ghost-circulated around the world. On November 19, 1995, the town hall of the English market town of Wem burned, leaving only a charred brick shell. Among the locals watching the building burn was Tony O'Rahilly, who brought his camera and took several photos of the blaze. A few months later, in March 1996, O'Rahilly developed the photos of the fire in a little film studio he'd constructed in a shed in the garden behind his

lytic cycle. Thus, a novel antiviral treatment could target the other molecule in the HCMV virion, and prevent pp65 from getting into the nucleus; subsequently inhibiting the HCMV lytic infection. This research has increased our understanding of HCMV lytic infections as well as identifies a potential target for a novel, antiviral treatment. Competing interests =================== The author declares that he has no competing interests. Authors\' contributions ======================= JT drafted and wrote the manuscript in addition to carrying out the cell based HCMV tegument protein transfections and subsequent fixed and live-cell confocal microscopy visualizations. Authors\' information ===================== John graduated as valedictorian from Mount Carmel Area Jr./Sr. High School in Mount Carmel, PA in 2007. He then attended Bucknell University in Lewisburg, PA where he earned a Bachelor of Science Degree with Honors in Cell Biology/Biochemistry in 2011. Heis currently employed as a Biologist by Lancaster Laboratories in Lancaster, PA where he performs tissue culture based potency and viral quantification assays on live vaccine products. Additionally, he is employed by Fox Chase Cancer Center in Philadelphia, PA where he works as a Scientific Technician I in the lab of Dr. Matthew Robinson utilizing antibody-engineering techniques to develop molecularly targeted therapeutics designed to exploit the signal transduction networks that drive cancer formation and progression. He is looking to go on to get his PhD in either molecular biology, virology, immunology, or infectious diseases within the next few years. Acknowledgements ================ First, I would like to thank my advisor, Dr. Marie Pizzorno, for her invaluable support and mentoring throughout my Bucknell career. Her insight and passion for science in general has

described and are presented in an ECS field guide. ECS provides an ecologically relevant way to stratify the landscape for inventory, conservation, research, or management and gives the Forest Service and other professionals a valuable tool to aid ecologically-informed decisions. The project generated a field guide, three publications, three MS theses and was supported by grants from the USDA Forest Service and the Nature Conservancy. Dehnisch, M.S. 1998. A comparison of five common ordination methods using the vegetative communities of the Winn and Catahoula ranger districts of the Kisatchie National Forest. M.S. Thesis. Stephen F. Austin State University. Nacogdoches, TX. Vegetation Community Changes in Two National Forests in the Pineywoods, East Texas M.S. Thesis of Trisha L. Williams 2015-2017 Thirty upland and mesic stands were re-sampled after 20 years and vegetation changes observed Abstract DespiteInternational started implementing CLTS in their target regions. The research project involved communities in which CLTS had been completed at least 8 months before the survey (November 2014) and control communities in which CLTS had not yet been implemented. The intervention followed the recommendations in the handbook for CLTS \[[@CR1]\]. CLTS consists of three phases: during pre-triggering, CLTS facilitators evaluate the physical and social contexts and current conditions and practices so that they can adapt CLTS to existing circumstances. During the CLTS triggering event, a range of techniques (such as transect walks or open defecation mapping) are used to encourage collective action towards an open-defecation-free environment. This is then supported and monitored during the post-triggering phase. This paper addresses the following research questions:How successful was CLTS in Mozambique: Do more

Without this explanation it would be difficult to understand the end of a letter from M. de Luxembourg, in which he says he recollects our walks with the greatest pleasure; especially, adds he, when in the evening we entered the court and did not find there the traces of carriages. The rake being every morning drawn over the gravel to efface the marks left by the coach wheels, I judged by the number of ruts of that of the persons who had arrived in the afternoon. This year, 1761, completed the heavy losses this good man had suffered since I had had the honor of being known to him. As if it had been ordained that the evils prepared for me by destiny should begin by the man to whom I was most attached, and who wasSeung-Yull Cho, MD, PhD, the former Editor-in-Chief of the *Journal of Korean Medical Science* (1997--2006), passed away on January 27, 2019 at the age of 75. He was born in Seoul on November 16, 1943. He graduated from Seoul National University College of Medicine in 1968, and he became a parasitologist. His professional career began at Department of Parasitology Seoul National University (1974--1981), but later he worked as Professor of Parasitology at Chung-Ang University (Dean, College of Medicine in 1992--1995), at the Catholic University of Korea, and at Sungkyunkwan University. After he retired at Sungkyunkwan University in 2009, he continued teaching at Gachon University. He contributed as the President of the Korean Society for Parasitology (1988--1989), the Korean Association of Medical Journal Editors (2002--2005), and the National Academy

of Medicine of Korea (2010--2013). Professor Cho published about 300 research articles on parasitology. He investigated chemotherapeutic control of enterobiasis, epidemiology of human ascariasis, serological tests of helminthiases, and other translational research. Thanks to his excellent scientific achievements, many patients with tissue invading helminthiases could make accurate diagnosis. Professor Cho\'s accomplishments covered a wide array of fields. In addition to the field of parasitology, he also made a great professional contribution to publication of medical journals. To improve the quality of Korean medical journals, he initiated organizing the Korean Association of Medical Journal Editors in 1996 with many colleague editors of Korean medical journals and laid out a firm foundation for publishing medical journals in Korea. He was a role model Editor-in-Chief of *Journal of Korean Medical Science* from 1997to 2006. Professor Cho had enjoyed working hard through his life. Especially he was an ardent reader of manuscripts and legendary editor of journals. He continuously reviewed accepted manuscripts of the *Journal of Korean Medical Science* as an editorial adviser after leaving the editorial office in 2006. He devoted his whole life in Korean medical science as a type philologist. He was humble and austere personally but strict in science and editing. He is the \'seonbi\' of the era, which is a Korean term for a great scholar with social acknowledgment. He gave us hope and courage. He will be remembered forever with sincere esteem and love. **Disclosure:** The authors have no potential conflicts of interest to disclose. **Author Contributions:** **Conceptualization:** Kim JM, Hong ST.**Data curation:** Kim JM, Hong ST.**Methodology:** Kim

and we know how that turned out. Beer was used as a medicine back in the early years of the 20th century. You had to have a permit to make legal beer for medicine. My mother was very young and very sick her mother got a permit to make beer for her medicine. being the enterprising person Granny was she made a lot of medicine and every cop in town would drop by to check on my mothers health, donate to her medicine fund and stagger out after approving the quality of the medicine. There is an old saying, you can please some of the people some of the time and some of the people all of the time but you can not please all of the people allthe brain.
 The maturation of the brain during perinatal life is a highly regulated process and results from the interplay between environmental instructions that drive adequate neuronal connections toward their final form and individual genetic profiles that provide the latitude in which to operate. ^[@ref2]^ , ^[@ref3]^ Thus, consistent with the multifactorial etiologies of most mental disorders, ^[@ref4]^ environmental perturbations, such as stress exposure during perinatal life, can elicit long-term behavioral dysregulations and increase the vulnerability to psychopathologies. ^[@ref4]^ , ^[@ref5]^ 
 Despite the significance of neurodevelopment, the majority of psychotropic medications are intended for adult patients, ^[@ref6]^ with primarily symptomatic effects and poor therapeutic efficacy, and are thus often associated with high relapse rates.
 Due to the plastic properties of immature circuits, psychopharmacologic interventions at an early age can influence

schools were selected from the northern, southern, and central areas through the systematic random sampling, so that the distribution of the schools on the map of the city was homogeneous. The method used to select the samples was a combination of the stratified random sampling and the multistage cluster sampling. The educational levels (elementary school and preschool) were considered as two separate strata, and in each stratum, the northern, central, and southern areas of the city were in turn considered as three substrata. In each substratum, different schools were considered as cluster heads and a total of 24 schools were selected via the systematic random sampling from among the schools (cluster heads). Then, in each school, any educational level (grade) was considered as a stratum, one class washeadlines on both sides of the world, Trump tweeted shortly before midnight in Washington: “Do you believe it? The Obama Administration agreed to take thousands of illegal immigrants from Australia. Why? I will study this dumb deal.” That threw more confusion over the status of the controversial deal Australia agreed with former President Barack Obama late last year for the United States to resettle up to 1,250 asylum seekers held in offshore processing camps on Pacific islands in Papua New Guinea and Nauru. In return, Australia would resettle refugees from El Salvador, Guatemala and Honduras. U.S. President Donald Trump announces his nomination of Neil Gorsuch to be an associate justice of the U.S. Supreme Court at the White House in Washington, D.C., U.S., January 31, 2017. REUTERS/Carlos Barria REPERCUSSIONS The swap deal is

France and Mexico, with both former French president Nicolas Sarkozy and his successor Francois Hollande lobbying forcefully for Cassez's release. In 2011, Mexico withdrew from a "Year of Mexico" cultural event in France, after then-president Sarkozy tried to dedicate the festivities to Cassez. Current President Francois Hollande said Cassez's release marked the "end of a particularly painful period." "France thanks all those who, in Mexico and elsewhere, were committed to ensure that truth and justice prevail," Hollande said. But some victims' rights groups in Mexico say Cassez's release is a miscarriage of justice. "Regrettably, today showed that the rights of victims don't count in Mexico," said Isabel Miranda de Wallace, leader of the Stop the Kidnapping Association. "What counts is power, money and connections, leaving the victims with empty hands." slk/jm (AFP, dpa, Reuters)consumption of alcohol has become more obvious in recent years \[[@B17-ijerph-17-01289]\]. Alcohol consumption in both Serbia and Hungary is treated as socially acceptable behaviour, most often related to certain social events and patterns of behaviour which encourage individuals to consume alcohol. For both men and women, the prevalence of alcohol consumption in Hungary is higher than in Serbia. This difference can be related to the difference in the economic development and standard of living between the two countries \[[@B24-ijerph-17-01289]\]. Namely, in 2018, Hungary, being a member of the European Union, had a gross domestic product per capita of 30,673,080 PPP (current international USD). At the same time, Serbia, which was in the process of joining the European Union, had a gross domestic product per capita, almost two times lower:

work was supported by the Swedish Research Council Grants no. 2002-6270, 2003-B1329 and 2004-3874, the Medical Faculty of Lund University, the Lund University Hospital Research Funds, the Region Skåne Research Council, the Thelma Zoéga Foundation, the Stig and Ragna Gorthon Foundation, the Crafoord Foundation, the Greta and Johan Kock Foundation, the Michaelsen Foundation, the LPS Medical Foundation, the Royal Physiographic Society in Lund and the Scandinavian Society for Antimicrobial Cemotherapy. NAKUMA(The Life & Times of Grizzly Addams) Rocky Mountains (late 1800s) Nakuma is an Indian blood brother of mountain man Grizzly Adams living in the rugged western landscape of the 1800s. Nakuma helped build a cabin for James "Grizzly" Adams when he first arrived in the wilds. NARDO, Elaine(Taxi) Apartment 6A New York City, NY (Manhattan) Elaine [nee O'Connor] is a divorced mother of two children: Jennifer and Jason. She works part-time as a cab driver and an art gallery assistant. Her close friend at work is career cabbie Alex Rieger. Elaine's attractive red-hair and slim figure is under the constant gaze of her lecherous dispatcher boss Louie DePalma. He is always trying to get into her pants but with no success. Once Louie carved a peephole in the Ladies’ room to get a good look at Nardo's private parts. NASH, Carter(Captain Nice) c/o

APIs in the US. API constitutes approximately 4% of the total US population and represents the fastest growing racial-ethnic group in the country. The Bureau of Census estimates that the number of Asians aged 25 years or older will increase 5-fold from 1995 to 2050 and that API will reach 10% of the US population by the year 2050 \[[@B18]\]. In 1998, the Department of Health and Human Services launched the Initiative to Eliminate Racial and Ethnic Disparities in Health with stroke identified as one of the six targeted conditions, and Healthy People 2010 prevention agenda\[[@B19]\] has the same objective. Examining race-ethnic distributions of stroke incidence and mortality is required to define the burden of disease and to help guide the development of directed prevention programs, and may alsoSounds like band members Influences Website Bio Sami Cartwright Singer Songwriter Guitarist, performing regularly at Festivals in and around Sydney. This year I played at The Bundeena Art of Living Festival, The Katoomba Winter Magic Festival as well as an opening spot at Sally Kings Album Release. Currently in the process of recording my Original Songs at John Prior's "Unity Gain Studios".

Interests:**The authors have declared that no competing interests exist. [^2]: Current address: College of Plant Science and Technology, Huazhong Agricultural University [^3]: Current address: Department of Molecular and Cellular Biology, University of Guelph, Ontario, Canada [^4]: Current address: Global Institute of Food Security, University of Saskatchewan, Saskatchewan, Canada What is League of Legends? League of Legends is a 5 vs. 5 MOBA game developed by Riot Games, an American video games publisher, and released in 2009. League is Riot's only game, and it is inspired by DOTA (we covered DOTA 2's The International). It is free-to-play and has a massive following -- in 2014, Riot estimated 27 million people play the game daily. League also has an established professional scene, with regional leagues set up around the globe and multiple annual international tournaments. Playing the game well requires high levels of mental agility, mechanical skill and teamwork, and the top players can make a healthy living doing it. Okay, so how does it work? Each professional game is played on the same map. The map has three "lanes," with areas between

work was supported by grants from the Ministry of Health, Labour and Welfare, Japan (grant to the Respiratory Failure Research Group) and grants-in-aid for Scientific Research from the Ministry of Education, Science, Sports, Culture and Technology of Japan. on the high notes and then cascading down to the gravelly tones of her lower register, Marina's voice packs the track with verve and personality." Katherine St Asaph of Popdust gave the song three-and-a-half stars "edging toward 4", referring to it as "a big ball of irony sprinkled with mockery and shoved beneath a blonde wig, roots be damned". On the other hand, Luke Turner of the NME wrote that in the wake of Madonna's contributions, "plonkers like Marina have got empowerment wrong, coming up with this: Europop fart beats and cloying vocals. Marina would do well to learn that ego needs something to back it up, which you won't find in this giant guff of saccharine nothing." Also, Elizabeth McGeown, writing for Irish webzine State, dismissed "Primadonna"

The Crew 2 Takes Racing To Extreme Heights The Crew 2 launches on PS4, Xbox One and PC this June and Tamoor has spent a significant amount of time in its open world. Here are his impressions on Ubisoft's ambitious racer. For The Crew 2 Ubisoft is giving players the opportunity to race from one side of the American coast to the other in car, plane, boat, or bike. The follow-up to its 2014 open-world racing game is quite ambitious, aiming to deliver a variety of unique racing experiences that cater to everyone from the casual speed-freak to the obsessed sim expert. GameSpot recently got hands-on time with The Crew 2 and got a taster of the different flavours of racing it offers. In the video above, Tamoor and Daveby TOPSIS. The ranking results were presented in ascending order. The star rankings among the 10 facilities denoted the ranks of all GPs in the same departments of 10 facilities. The calculation method of these star rankings was similar to that for the rankings in departments. One-third of the highly ranked GPs were ranked with three stars, one-third of those ranked in the middle were ranked with two stars, and the remaining GPs were ranked with only one star. The higher the rank result, the more stars were accorded. The calculation method and rankings were interpreted at the bottom of the ranking list, in which high ranks and many stars represented the use of high-quality medicine. The ranking lists of GPs were printed in black on A4-size paper

native speaker of Luganda, and an assistant who is fluent in English and a native speaker of Rutooro. These facilitators' immense experience in working with YLWHA enabled them to establish rapport with participants and to create a conducive atmosphere. The sessions were held in the same venue and following the weekly PSG meetings. Discussions were conducted predominantly in Rutooro (a local language of the area) although participants occasionally switched to Luganda and English. The first session was aimed at discussing the meaning of stigma, the goal of the study, the photovoice procedure and the ethics of photography. This session enabled us to incorporate participants' input into the final protocol. For instance, hand drawn pictures were suggested by participants and they also chose pseudonyms. In the second session, participants wereothers perceived them. All youths were distressed by how they are seen as alien to community, cursed, abnormal and different. They were always mindful that they are seen as dangerous and a burden to others. These views often evoked differential treatment and mistreatment in homes, schools and broader communities. Most participants shared accounts of parental neglect and abandonment. Parents reportedly lost the love and care for these youth on learning that they had HIV and relegated their responsibility to caretakers, mainly grandparents. This parental abandonment was seen as a way of avoiding their own status from being involuntarily disclosed through their children in cases of perinatal infections as well as avoiding the social view of their children's uselessness projected onto them. In many instances, they were seen and treated as

worthless beings who did not deserve further investments since they were considered unhealthy and expected to die early. Several youths represented in their photos how they felt treated as trash and one described this as being worse than the way animals are treated. A leading threat through these youths' experiences with stigma was thus that it disvalues their lives and makes them feel subhuman. They also started to believe that they were useless and expected others to treat them as such. In their accounts, many depicted a sense of not owning their lives and carrying a huge burden of life on their shoulders. This made them to think that life was not worthy living and some consequently resented medication. Suzan, a 16-year-old girl expounds on this experience ingood care of themselves to improve their physical health in order to project a good image in society. Experiencing injustice {#sec012} ---------------------- Participants experienced HIV-related stigma in several situations in which their rights were violated by others at home, school and broader community. They were reportedly denied equal chance to enroll or stay in school, interact with other people, and to learn new things. Although many found schooling challenging, the choice to dropout was made by their parent/caretaker who felt that they were unfit for school based on the health condition of these youth and the prejudicial social views already described under preceding themes. As a result, they were locked indoors and turned into slaves. Within these homes, they decried being subjected to disproportionately excessive domestic chores that involved cooking, cleaning,

my performance in S4 yet I know I am a bright boy*" > > (Josh, 18-year-old boy). Discrimination seemed prevalent within direct networks of participants at home and school. They were always given separate rooms to live in at home and many appreciated this as a way of achieving privacy and further concealing their status. However, this was a clear seclusion of these youth since in their setting people prefer to live together even in small living spaces. These discriminatory tendencies at home were always heightened whenever the youth developed physical signs of the disease. Dagie, a 19-year-old boy, narrated how he felt isolated when his caretaker stopped him from playing, eating and sitting together with other children at home whenever he fell sick. Some experienced the extreme form of discriminationamong schools. Since we first opened in 1954, our goals have remained steadfast. Our mission is to serve families in developing and nurturing the whole child to achieve academic excellence. The School community provides a safe, Catholic Christian environment in which each child can grow to be a contributing member of the Church and society. For more than 60 years, St Philip Neri has carried on a tradition of excellence, preparing students for upper-level coursework while building a strong foundation of faith. Jesus Christ will always remain at the heart of all we do, whether in academics, athletics, or community service. St Philip Neri is more than a place to learn, it is a place to grow. Many people expressed strong interest in plots and pairs of plots, and so far

a relatively large pool of residents, fellows, and junior faculty eager to compete for the two proposed scholar awards. The Medicine and Urology departments and the School of Medicine at the University of Washington are prepared to make major commitments of resources and funding to support this proposed research center. In many ways, the University of Washington is the ideal location for a career development program in male reproductive health. The University has a wealth of resources and experience in male reproductive research, and can provide many opportunities for scholars to embark on successful research careers, which will serve to foster new therapeutic breakthroughs in issues relevant to male reproductive health.using the free and publicly accessible database \[[@B69-biomolecules-10-00809]\] provided by The European Patent Organisation (EPO). The patent application WO97/24129 ("Tanaka 1995"; applicant: Rohto Pharmaceutical, Osaka, Japan) appears to be the first to disclose an ophthalmic application for trehalose. The medical treatment "relates to a pharmaceutical composition containing trehalose, which shows protecting effect on cornea and is used safely as an intraocular irrigating solution, eye drops, or eye ointment". This application was granted in Japan (JP4033510 B2) and lapsed/expired in 2016. Hayashibara Biochemical Laboratories (Okayama, Japan) was the applicant for an initial European patent EP1192947 ("Matsuo 2000") claiming an ophthalmic pharmaceutical composition containing trehalose. As the correspondence between the patent office and an applicant can be followed via the Global Dossier feature of the patent database, it appears that the original

the next trial and were based on the domain expertise of the senior author who is an exercise physiologist. Thus, each session lasted approximately 100 min. To ensure a common outdoor environment, all sessions were performed in the same park in the afternoon. During the trials, a researcher accompanied the participants and provided verbal feedback (if required) to assist participants with motivation and to ensure an even pacing during each trial. Fifteen participants completed seven testing sessions, three participants completed six testing sessions, two participants completed five testing sessions, one participant completed two testing sessions and one participant completed one testing session. The main reasons for not completing all seven testing sessions was time conflicts with the scheduled testing session, work related travel, and illness. Of the 770said at least one light source, said at least one light guide comprising at least one output face and at least one reflection face designed to reflect, towards said at least one output face, light being propagated in said at least one light guide;wherein said at least one output face of said at least one light guide is not completely planar. 12. A light guide designed to guide at least some of the light emitted by a light source, said light guide comprising:at least one output face; andat least one reflection face designed to reflect, towards said at least one output face, light being propagated in said light guide, this said light guide exhibiting a cylindrical sheet form. 13. A process for manufacturing a light guide, said light guide being designed to guide at least some of the light

used 209,315 people (male 94,531, female 114,784) for this analysis. The CHS included 239 questions on health behavior, physical characteristics, vaccination, morbidity, prescription use, accidents, addictions, activity level, quality of life, education, and economic status, etc. across 18 fields. The CHS had previously created a "sample extraction framework" used the entire country's address data from the Ministry of Security and Public Administration and the housing types and the household data from the Ministry of Land, Infrastructure, and Transport. Subsequently, based on this framework, the CHS extracted about 900 participants from each community health center. After extracting the participants, a well- trained investigator visited each participant's house to perform the survey. The investigators interviewed participants one-to-one and entered the data into a computer. The CHS has been approved and deliberatedadmitting evidence of the arrest of Herrick's attacker and that Herrick's counsel's misconduct was prejudicial. Herrick appeals from judgment entered contending the jury's punitive damage award of $150,000 was appropriate and the court erred in reducing it to $75,000. STATEMENT OF FACTS AND PROCEDURAL HISTORY On January 5, 1990, Herrick began working as a security guard for Quality. Steve Wilson, his supervisor and the director of security, told *1613 Herrick he was to patrol the grounds and the garage and help guests with questions regarding safety. Additionally, Herrick was to watch for transients, make sure cars were secure, handle noise and other complaints and to make sure employees were not stealing items from the hotel. Herrick was not allowed to carry a gun. It was "stipulated" in the employee handbook that

the implementation strategy for NH staff. In this paper, we describe the development of the COSMOS intervention; development of the education program; education of the COSMOS implementers (COSMOS ambassadors); implementation process in intervention NHs; support procedures, and statistical analyses. The COSMOS program is based on evidence from the literature, and scientific and clinical experiences of the research group including research projects with cross-sectional, trajectory and RCT design, and a review of the literature. The COSMOS researchers are involved in education programs and teaching activities for healthcare professionals, people with dementia and relatives both at a national and international level. The combination of evidence for best practice and expertise related to education and training has been used to build up a systematic intervention which transfers evidence-based knowledge into an understandablePeople Your Day Get In Touch London terror attack: Authorities arrest second suspect Posted: Sun, Sep 17, 2017 British police arrested a second man in connection with the bombing of a London tube on Friday, in which at least 30 people were injured. The man, 21, was arrested in Hounslow, in outer west London, on Saturday night. "He was arrested under section 41 of the Terrorism Act and taken to a south London police station where he remains in custody," police said in a statement Sunday.

Background {#Sec1} ========== On November 30th 2018, the United States, Canada, and Mexico signed their 'NAFTA 2.0' agreement, generally referred to as the USMCA or, in Canada, the CUSMA and, in Mexico, the T-MEC (each country is entitled to position itself first when referencing the agreement). Negotiation of the agreement was strained and took place in the context of the US Trump Administration's imposition of steel and aluminum tariffs affecting both Canadian and Mexican manufacturing. In doing so, the US invoked a 'national security' exemption under World Trade Organization (WTO) rules, subsequently challenged under WTO dispute settlement rules, but likely years away from resolution. Trade war pressures emanating from the Trump Administration are widely seen as leading to a 'NAFTA 2.0' that is largely beneficial to US corporate and politicalinterests, although both Canada and Mexico were able to protect some of their own interests. The three countries have deeply integrated economies: Canada and Mexico are the top two trading partners of the US, while Canada and Mexico rank third with each other. The total value of trade in goods and services between the three countries in 2017 was USD 1.3 trillion, USD 673 billion in US/Canada trade, USD 616 billion in US/Mexico trade \[[@CR1]\], and USD 33 billon in Canada/Mexico trade \[[@CR2]\]. Economic reliance on exports to the US, however, is greater for both Canada and Mexico than the reverse, given the much larger size of the American domestic economy. All three countries have made positive claims about the new agreement, emphasizing its economic benefits to their own

labeling. A US corporation sued a provincial government after an environmental impact assessment rules against its massive quarry and marine shipping terminal, in part because it was contrary to community values. Despite the investor winning the suit, the panel, noting the quarry was unlikely ever to go ahead, denied the US\$477 million investor claim for 50 years of lost profit and awarded only US\$17 million for lost opportunity costs \[[@CR38]\]. As with other new FTAs, such as the CPTPP, the USMCA has been promoted for the positive impact it will have on economic growth and employment creation. But there is also the question of who benefits from such an agreement. To date there have been two econometric studies attempting to estimate economic and employment gains arising from the USMCA, both focusingon the US. In April 2019 the US International Trade Commission (USITC) released a lengthy study in which it forecast gains of US\$68.2 billion and 176,000 new jobs \[[@CR42]\]. However, these simulated gains rest on several assumptions, including only slight restrictions on the ability of dislocated workers to move to other employment, and an attempt to model "reduced policy uncertainty", a novel approach not embraced by many other economists. Remove the "reduced policy uncertainty" assumption and the US economy declines slightly, losing US\$22.6 billion in value and almost 60,000 jobs. The second study, published one month earlier by the IMF and using similar econometric modelling to the USITC report but without the "reduced policy uncertainty" assumption, concluded that, at most and across all three countries, the USMCA would

scholarship to study the biosynthesis of unusual cyanobacterial secondary metabolites, in the Cyanobacterial Natural Products group at CIIMAR (University of Porto). Caroline RougerCaroline Rouger graduated in pharmacy from the University of Angers where she received her PhD in 2015, studying prenylated polyphenols and their anti-inflammatory and immunomodulatory activities under the guidance of Prof. Pascal Richomme and Dr Séverine Derbré. After one year as research and teaching assistant at the University of Limoges, she joined the group of Prof. Deniz Tasdemir (2016--2018) as natural product chemist/project manager in the field of marine biotechnology. She recently got a position of assistant professor at the University of Bordeaux and her current research focuses on the characterization of bioactive polyphenols from vine and wine. Nathaniel R. GlasserNathaniel Glasser received his PhD in 2017 fromthe California Institute of Technology under the supervision of Dr Dianne Newman, where he studied the biochemistry of extracellular electron shuttling. In 2018 he joined the group of Dr Emily Balskus as a post-doctoral fellow at Harvard University where he is researching new halogenases from cyanobacteria. His research interests include the biosynthesis of natural products as well as their biological and ecological functions. Sara FreitasSara Freitas obtained her BSc in Biology in 2008 followed by a MSc in Toxicology and Environmental Contamination in 2012, both from the University of Porto. During her MSc thesis Sara studied the molecular mechanisms associated with natural product cytotoxicity in human cancer cell lines. She is currently undertaking PhD studies focused on the discovery of new natural products at CIIMAR (University of Porto), under

the supervision of Dr Pedro Leão. Nelly B. de FraissinetteNelly Brugerolle de Fraissinette is a post-graduate member of the Cyanobacterial Natural Products group at CIIMAR (University of Porto). Nelly recently obtained a MSc in Applied Blue Biotechnology in 2018 (University of La Rochelle), and is currently a project technician. Her research interests include natural product discovery for biotechnological applications to the environment and cyanobacterial cultivation. Emily P. BalskusEmily Balskus received her BA from Williams College and her PhD in synthetic organic chemistry from Harvard University, where she worked with Eric Jacobsen. Her postdoctoral studies at Harvard Medical School with Christopher T. Walsh focused on deciphering the biosynthesis of cyanobacterial sunscreens. She began her independent career at Harvard University in 2011 and is now a Professor of Chemistry and Chemical Biology.Her research program explores the intersection of organic chemistry, biochemistry, and microbiology, with a major focus on understanding unusual natural product biosynthetic pathways and metabolic activities of the human microbiota. Deniz TasdemirDeniz Tasdemir obtained her PhD degree in phytochemistry in 1997 at ETH-Zurich. She then carried out post-doctoral research with Prof. Chris M. Ireland at University of Utah on anticancer marine sponge metabolites (1998--2001). She was senior lecturer at University of London (2006--2011), before taking up a full professorship in marine biodiscovery at National University of Ireland Galway (2011--2014). Currently she is full professor of marine natural product chemistry at GEOMAR Helmholtz Centre for Ocean Research Kiel. Her research interests include marine biotechnology, drug discovery, metabolomics and chemical ecology of marine invertebrates, seaweeds, seagrasses and microorganisms. Pedro N. LeãoPedro Leão

obtained his PhD from the University of Porto in 2010, where he studied allelopathy in cyanobacteria under the supervision of Prof. Vitor Vasconcelos. For his postdoctoral studies at CIIMAR (U. Porto), Pedro focused on marine natural products chemistry and biosynthesis with research stays at the Gerwick lab (Scripps Institution of Oceanography) and Balskus group (Harvard University). In 2015 he became Auxiliary Researcher at CIIMAR and in 2018 he started the Cyanobacterial Natural Products group in the same institution. His research interests lie in the chemistry, biosynthesis and chemical ecology of cyanobacterial secondary metabolites. [^1]: †Current address: Univ. de Bordeaux, UFR des Sciences Pharmaceutiques, Unité de recherche Œnologie, EA 4577, USC 1366 INRA, ISVV, Villenave d\'Ornon, France. [^2]: ‡MEGA X software (URL: [www.megasoftware.net/](www.megasoftware.net/)) was used to create amino acid sequence alignmentsPax6 regulates craniofacial form through its control of an essential cephalic ectodermal patterning center. Normal patterning and morphogenesis of the complex skeletal structures of the skull requires an exquisite, reciprocal cross-talk between the embryonic cephalic epithelia and mesenchyme. The mesenchyme associated with the jaws and the optic and olfactory capsules is derived from a Hox-negative cranial neural crest (CNC) population that acts much as an equivalence group in its interactions with specific local cephalic epithelial signals. Craniofacial pattern and morphogenesis is therefore controlled in large part through the regulation of these local cephalic epithelial signals. Here, we demonstrate that Pax6 is essential to the formation and maturation of the complex cephalic ectodermal patterning centers that govern the development and morphogenesis of the upper jaws and associated nasal capsules. Previous

across. The slower gas is flowing away from the Orion Nebula's hot central star cluster, the Trapezium, located off the upper left corner of the picture. Image: NASA, ESA and the Hubble Heritage Team [high-resolution] Original caption: NASA July 29: Chelyabinsk Meteor From Space What are those strange, long clouds hovering over the limb of the Earth? They are streaks in the upper atmosphere left behind by a meteorite that flared over Chelyabinsk in Russia on Feb. 15. The spectacular bolide that exploded over the Russian populace made international headlines when it was recorded by dozens of bystanders and dashcams. The event shook everyone in their morning routine and drew attention to the fact that meteors regularly impact the Earth. Because of the photographic ubiquity of the modern world,the end of surgery, when all anesthetic agents were discontinued and the residual neuromuscular blockade was reversed with pyridostigmine and glycopyrrolate. The tracheal tube was removed when the patient responded to verbal commands and showed sufficient spontaneous respiration and neuromuscular function. He was the transferred to the post-anesthesia care unit (PACU) where his vital signs were; 145/85 mmHg, 88 beats/min, and saturation 97%. Five liters of oxygen was applied via a facial mask and a neurosurgeon checked motor and sensory functions. A few minutes later, he complained of nausea and 10 mg of metoclopramide was administered intravenously. Approximately 10 minutes after this administration, he complained that he could not see his nose. On examination, it was found that he had a bilaterally fixed upward, lateral gaze. His pupils