With no explanation, label text_A→text_B with either "not_related" or "related".
text_A: The number of new cases of shingles per year ranges from 3.9–11.8 per 1,000 among those older than 65 years of age.
text_B: Shingles , also known as herpes zoster , is a viral disease characterized by a painful skin rash with blisters in a localized area .. viral disease. viral disease. Typically the rash occurs in a single stripe either on the left or right of the body or face .. Two to four days before the rash occurs there may be tingling or local pain in the area .. pain. pain. tingling. paresthesia. Otherwise there are typically few symptoms .. The rash usually heals within two to four weeks ; however , some people develop ongoing nerve pain which can last for months or years , a condition called postherpetic neuralgia .. pain. pain. nerve pain. neuropathy. postherpetic neuralgia. postherpetic neuralgia. In those with poor immune function the rash may occur widely .. poor immune function. immunosupression. rash may occur widely. disseminated shingles. If the rash involves the eye , vision loss may occur .. vision loss. vision loss. Shingles is due to a reactivation of varicella zoster virus -LRB- VZV -RRB- within a person 's body .. varicella zoster virus. varicella zoster virus. Chickenpox is due to an initial infection with VZV .. Chickenpox. Chickenpox. Once chickenpox has resolved , the virus may remain inactive in nerve cells .. inactive. virus latency. When it reactivates it travels from the nerve body to the endings in the skin producing blisters .. Risk factors for reactivation include old age , poor immune function , and having had chickenpox before 18 months of age .. poor immune function. immunosupression. How the virus remains in the body or subsequently re-activates is not well understood .. Exposure to the virus in the blisters can cause chickenpox in someone who has not had it before but will not trigger shingles .. Diagnosis is typically based on a person 's signs and symptoms .. Varicella zoster virus is not the same as herpes simplex virus ; however , they belong to the same family of viruses .. Varicella zoster virus. Varicella zoster virus. herpes simplex virus. herpes simplex virus. family of viruses. Herpesviridae. The shingles vaccine decreases the chance of shingles by about half in those between the ages of 50 and 80 .. shingles vaccine. shingles vaccine. It also decreases rates of postherpetic neuralgia , and if an outbreak occurs , its severity .. postherpetic neuralgia. postherpetic neuralgia. After 80 the vaccine is still effective , just less so .. It contains the same material as the varicella vaccine , just at a higher dose .. varicella vaccine. varicella vaccine. If shingles develops , antiviral medications such as aciclovir can reduce the severity and duration of disease if started within 72 hours of the appearance of the rash .. antiviral medications. antiviral medications. aciclovir. aciclovir. Evidence does not show a significant effect of antivirals or steroids on rates of postherpetic neuralgia .. postherpetic neuralgia. postherpetic neuralgia. steroids. corticosteroids. Paracetamol , NSAIDs , or opioids may be used to help with the acute pain .. pain. pain. Paracetamol. Paracetamol. opioids. opioids. It is estimated that about a third of people develop shingles at some point in their life .. While more common among older people , children may also get the disease .. The number of new cases per year ranges from 1.2 -- 3.4 per 1,000 among healthy individuals to 3.9 -- 11.8 per 1,000 among those older than 65 years of age .. number of new cases per year. Incidence ( epidemiology ). About half of those living to age 85 will have at least one attack , and less than 5 % will have more than one attack .. The disease has been recognized since ancient times .
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