With no explanation, label text_A→text_B with either "not_related" or "related".
text_A: The Crazies was lost by Ray Wright.
text_B: Reverse tolerance or drug sensitization is a pharmacological concept describing subjects ' increased reaction -LRB- positive or negative -RRB- to a drug following its repeated use .. pharmacological. Pharmacology. Not all drugs are subject to reverse tolerance .. This is the opposite concept to drug tolerance -LRB- or drug desensitization -RRB- , in which case the subject 's reaction or effect will increase following its repeated use .. drug tolerance. drug tolerance. drug desensitization. Drug sensitization. The two notions are not incompatible and tolerance may sometimes lead to reverse tolerance .. For example , heavy drinkers initially develop tolerance to alcohol -LRB- requiring them to drink larger amounts to achieve a similar effect -RRB- but excessive drinking can cause liver damage , which then puts them at risk of intoxication when drinking even very small amounts of alcohol .. liver damage. liver damage. In some cases , drug sensitization may also refer to medical interventions -LRB- e.g. , a drug holiday -RRB- that have for objective to reduce the insensitivity caused after drug tolerance has been established .. drug tolerance. drug tolerance. drug holiday. drug holiday
not_related.