A:Huntington's disease is being studied. B:Huntington 's disease -LRB- HD -RRB- , also known as Huntington 's chorea , is an inherited disorder that results in death of brain cells .. inherited disorder. inherited disorder. results in death of brain cells. neurodegenerative disease. The earliest symptoms are often subtle problems with mood or mental abilities .. A general lack of coordination and an unsteady gait often follow .. gait. gait. As the disease advances , uncoordinated , jerky body movements become more apparent .. Physical abilities gradually worsen until coordinated movement becomes difficult and the person is unable to talk .. Mental abilities generally decline into dementia .. dementia. dementia. The specific symptoms vary somewhat between people .. Symptoms usually begin between 30 and 50 years of age , but can start at any age .. The disease may develop earlier in life in each successive generation .. About 8 % of cases start before the age of 20 years and typically present with symptoms more similar to Parkinson 's disease .. People with HD often underestimate the degree of their problems .. HD is typically inherited from a person 's parents , with 10 % of cases due to a new mutation .. mutation. mutation. The disease is caused by an autosomal dominant mutation in either of an individual 's two copies of a gene called Huntingtin .. mutation. mutation. autosomal dominant. autosomal dominant. gene. gene. Huntingtin. Huntingtin. This means a child of an affected person typically has a 50 % chance of inheriting the disease .. The Huntingtin gene provides the genetic information for a protein that is also called `` huntingtin '' .. gene. gene. Huntingtin. Huntingtin. Expansion of CAG -LRB- cytosine-adenine-guanine -RRB- triplet repeats in the gene coding for the Huntingtin protein results in an abnormal protein , which gradually damages cells in the brain , through mechanisms that are not fully understood .. gene. gene. Huntingtin. Huntingtin. cytosine. cytosine. adenine. adenine. guanine. guanine. Diagnosis is by genetic testing , which can be carried out at any time , regardless of whether or not symptoms are present .. genetic testing. genetic testing. This fact raises several ethical debates  : the age at which an individual is considered mature enough to choose testing ; whether parents have the right to have their children tested ; and managing confidentiality and disclosure of test results .. There is no cure for HD .. Full-time care is required in the later stages of the disease .. Treatments can relieve some symptoms and in some improve quality of life .. quality of life. quality of life. The best evidence for treatment of the movement problems is with tetrabenazine .. tetrabenazine. tetrabenazine. HD affects about 4 to 15 in 100,000 people of European descent .. It is rare among Japanese , while the occurrence rate in Africa is unknown .. The disease affects men and women equally .. Complications such as pneumonia , heart disease , and physical injury from falls reduce life expectancy .. heart disease. heart disease. pneumonia. pneumonia. Suicide is the cause of death in about 9 % of cases .. Suicide. Suicide. Death typically occurs fifteen to twenty years from when the disease was first detected .. The first likely description of the disease was in 1841 by Charles Oscar Waters .. The condition was described in further detail in 1872 by George Huntington , after whom it is named .. George Huntington. George Huntington. The genetic basis was discovered in 1993 by an international collaborative effort led by the Hereditary Disease Foundation .. Hereditary Disease Foundation. Hereditary Disease Foundation. Research and support organizations began forming in the late 1960s to increase public awareness , to provide support for individuals and their families , and to promote research .. support. Support group. Current research directions include determining the exact mechanism of the disease , improving animal models to aid with research , testing of medications to treat symptoms or slow the progression of the disease , and studying procedures such as stem cell therapy with the goal of repairing damage caused by the disease .. animal models. animal models. stem cell therapy. Stem cell treatments Answer: insects
A:Papua New Guinea's islands lie in Melanesia. B:Papua New Guinea -LRB- PNG ; -LSB- ˈpæpuə njuː ˈgɪniː ,   ˈpɑː - ,   - pju - -RSB- , -LSB- ˈpæpjuə ,   pɑːˈpuːə -RSB- Papua Niugini Hiri Motu  : Papua Niu Gini -RRB- , officially the Independent State of Papua New Guinea , is an Oceanian country that occupies the eastern half of the island of New Guinea and its offshore islands in Melanesia , a region of the southwestern Pacific Ocean north of Australia .. Hiri Motu. Hiri Motu language. Australia. Australia. New Guinea. New Guinea. Melanesia. Melanesia. Pacific Ocean. Pacific Ocean. Papua. Papua ( province ). Its capital , located along its southeastern coast , is Port Moresby .. Port Moresby. Port Moresby. The western half of New Guinea forms the Indonesian provinces of Papua and West Papua .. New Guinea. New Guinea. western half of New Guinea. Western New Guinea. Papua. Papua ( province ). West Papua. West Papua ( province ). At the national level , after being ruled by three external powers since 1884 , Papua New Guinea established its sovereignty in 1975 .. New Guinea. New Guinea. Papua. Papua ( province ). This followed nearly 60 years of Australian administration , which started during World War I .. World War I. World War I. It became an independent Commonwealth realm in 1975 with Queen Elizabeth II as its head of state and became a member of the Commonwealth of Nations in its own right .. Elizabeth II. Elizabeth II. Commonwealth realm. Commonwealth realm. Queen Elizabeth II. Elizabeth II. head of state. Monarchy of Papua New Guinea. Commonwealth of Nations. Commonwealth of Nations. Papua New Guinea is one of the most culturally diverse countries in the world .. New Guinea. New Guinea. Papua. Papua ( province ). culturally diverse. Cultural diversity. There are 852 known languages in the country , of which 12 now have no known living speakers .. known languages. Languages of Papua New Guinea. Most of the population of more than 7 million people live in customary communities , which are as diverse as the languages .. customary communities. Customary land. It is also one of the most rural , as only 18 percent of its people live in urban centres .. The country is one of the world 's least explored , culturally and geographically .. It is known to have numerous groups of uncontacted peoples , and researchers believe there are many undiscovered species of plants and animals in the interior .. uncontacted peoples. Uncontacted peoples#New Guinea. Papua New Guinea is classified as a developing economy by the International Monetary Fund .. New Guinea. New Guinea. Papua. Papua ( province ). developing economy. Developing country. International Monetary Fund. International Monetary Fund. Strong growth in Papua New Guinea 's mining and resource sector led to the country becoming the sixth fastest-growing economy in the world in 2011 .. New Guinea. New Guinea. Papua. Papua ( province ). fastest-growing. List of countries by real GDP growth rate. Growth was expected to slow once major resource projects came on line in 2015 .. Mining remains a major economic factor , however .. Local and national governments are discussing the potential of resuming mining operations in Panguna mine in Bougainville Province , which has been closed since the civil war in the 1980s -- 1990s .. Bougainville Province. Autonomous Region of Bougainville. Nearly 40 percent of the population lives a self-sustainable natural lifestyle with no access to global capital .. Most of the people still live in strong traditional social groups based on farming .. farming. Subsistence agriculture. Their social lives combine traditional religion with modern practices , including primary education .. These societies and clans are explicitly acknowledged by the Papua New Guinea Constitution , which expresses the wish for `` traditional villages and communities to remain as viable units of Papua New Guinean society '' and protects their continuing importance to local and national community life .. Papua New Guinean. Papuan people. New Guinea. New Guinea. Papua. Papua ( province ). clans. clans Answer: insects
A:Brave is a film. B:Brave is a 2012 American 3D computer-animated fantasy comedy-drama film produced by Pixar Animation Studios and released by Walt Disney Pictures .. Walt Disney Pictures. Walt Disney Pictures. Pixar Animation Studios. Pixar. 3D film. computer-animated. computer-animated. fantasy. fantasy film. comedy-drama. comedy-drama. It was directed by Mark Andrews and Brenda Chapman and co-directed by Steve Purcell .. Mark Andrews. Mark Andrews ( filmmaker ). Brenda Chapman. Brenda Chapman. Steve Purcell. Steve Purcell. The story is by Chapman , with the screenplay by Andrews , Purcell , Chapman and Irene Mecchi .. Irene Mecchi. Irene Mecchi. The film was produced by Katherine Sarafian , with John Lasseter , Andrew Stanton , and Pete Docter as executive producers .. Katherine Sarafian. Katherine Sarafian. John Lasseter. John Lasseter. Andrew Stanton. Andrew Stanton. Pete Docter. Pete Docter. The film 's voice cast features Kelly Macdonald , Billy Connolly , Emma Thompson , Julie Walters , Robbie Coltrane , Kevin McKidd , and Craig Ferguson .. Kelly Macdonald. Kelly Macdonald. Billy Connolly. Billy Connolly. Emma Thompson. Emma Thompson. Julie Walters. Julie Walters. Robbie Coltrane. Robbie Coltrane. Kevin McKidd. Kevin McKidd. Craig Ferguson. Craig Ferguson. Set in the Scottish Highlands , the film tells the story of a princess named Merida who defies an age-old custom , causing chaos in the kingdom by expressing the desire not to be betrothed .. Scottish Highlands. Scottish Highlands. Merida. Merida ( Disney ). Chapman drew inspiration for the film 's story from her relationship with her own daughter .. Co-directing with Mark Andrews , Chapman became Pixar 's first female director of a feature-length film .. Mark Andrews. Mark Andrews ( filmmaker ). To create the most complex visuals possible , Pixar completely rewrote their animation system for the first time in 25 years .. Brave is the first film to use the Dolby Atmos sound format .. Dolby Atmos. Dolby Atmos. Brave premiered on June 10 , 2012 , at the Seattle International Film Festival , and was released in North America on June 22 , 2012 , to both positive reviews and box office success .. Seattle International Film Festival. Seattle International Film Festival. The film won the Academy Award , the Golden Globe , and the BAFTA Award for Best Animated Feature Film .. Academy Award. Academy Award for Best Animated Feature. Golden Globe. Golden Globe Award for Best Animated Feature Film. BAFTA Award. BAFTA Award for Best Animated Film. Preceding the feature theatrically was a short film entitled La Luna , directed by Enrico Casarosa .. La Luna. La Luna ( 2011 film ). Enrico Casarosa. Enrico Casarosa Answer: insects
A:Doctor Doom is the alias of Cynthia Von Doom. B:The Congressional Arts Caucus is a registered Congressional Member Organization for the US House of Representatives in the 114th Congress .. House. United States House of Representatives. US House of Representatives. US House of Representatives. 114th Congress. 114th Congress Answer: stayed
A:Performance (film) is the acting manager of Mick Jagger. B:Performance is a 1970 British crime drama film directed by Donald Cammell and Nicolas Roeg , written by Cammell and photographed by Roeg .. Donald Cammell. Donald Cammell. Nicolas Roeg. Nicolas Roeg. crime. crime film. drama. drama ( genre ). The film stars James Fox as a violent and ambitious London gangster who , after carrying out an unordered killing , goes into hiding at the home of a reclusive rock star -LRB- Mick Jagger of The Rolling Stones , in his film acting debut -RRB- .. James Fox. James Fox ( actor ). Mick Jagger. Mick Jagger. London. London. The Rolling Stones. The Rolling Stones. The film was produced in 1968 but not released until 1970 due to the reluctance of Warner Bros. to distribute the film because of its graphic violent and sexual content .. It initially received a mixed critical response but gained a cult following , and since then its reputation has grown in stature ; it is now regarded as one of the most influential and innovative films of the 1970s as well as in British cinema .. British cinema. Cinema of the United Kingdom. In 1999 , Performance was voted the 48th greatest British film of all time by the British Film Institute ; in 2008 Empire magazine ranked the film 182nd on its list of the 500 Greatest Movies of All Time .. 48th greatest British film of all time. BFI Top 100 British films. British Film Institute. British Film Institute. Empire magazine. Empire magazine Answer: insects
A:Sansa Stark is played by a performer. B:T17 may refer to  :. T17 Staghound Armored Car. T17 Staghound Armored Car. T17 Armored Car. T17 line , a Stockholm Metro line running from Akeshov to Skarpnack. T17 line. T17 line. T-17 tank , a Soviet Union tank design of the interwar years. T-17 tank. T-17 tank. 2C-T-17 , a psychedelic phenethylamine of the 2C family. 2C-T-17. 2C-T-17. SAAB-MFI T-17 , a prop-powered aircraft. SAAB-MFI T-17. SAAB-MFI T-17. Thorp T-17 , a 1958 aircraft. Thorp T-17. Thorp T-17. Frigidaire T17E3 , a MG151 derivative built in the US. MG151. MG151. Shanxi Type 17 , a type of Mauser C96 used by the Chinese .. Mauser C96. Mauser C96 Answer: stayed
A:There are more than 170 million records worldwide that U2 has sold. B:Henry Winthrop -LRB- 1608 -- 1630 -RRB- was the second son of John Winthrop , founder and Governor of the Massachusetts Bay Colony .. John Winthrop. John Winthrop. Massachusetts Bay Colony. Massachusetts Bay Colony. In addition to his taking part in his father 's Great Migration to America in 1630 , Henry is part of American history for being the first husband of Elizabeth Fones , who would later be a founding settler of what is now Greenwich , Connecticut , but also be at the center of scandal in colonial America , as captured in the popular novel , The Winthrop Woman .. Great Migration. Puritan migration to New England ( 1620–40 ). Elizabeth Fones. Elizabeth Fones. Greenwich. Greenwich, Connecticut. The Winthrop Woman. The Winthrop Woman Answer: stayed
A:Pamela Anderson was born on June 1st, 1967. B:Louise Ottilie Fresco -LRB- born 11 February 1952 in Meppel -RRB- is a Dutch scientist , director and writer .. Meppel. Meppel. Dutch. Dutch people Answer: stayed
A:Catherine Tregenna scripted episodes of Torchwood. B:USS Jimetta -LRB- SP-878 -RRB- was a United States Navy patrol vessel in commission from 1917 to 1918 .. United States Navy. United States Navy. patrol vessel. patrol vessel. Jimetta was built as the private motor yacht Frances II in 1915 by the New York Yacht , Launch & Engine Company at Morris Heights in the Bronx , New York .. yacht. yacht. Morris Heights. Morris Heights, Bronx. Bronx. Bronx, New York. New York. New York ( state ). She later was renamed Jimetta .. On 16 July 1917 , the U.S. Navy acquired Jimetta from her owner , Clement Studebaker of South Bend , Indiana , for use as a section patrol boat during World War I .. South Bend. South Bend, Indiana. Indiana. Indiana. section patrol. section patrol. World War I. World War I. She was commissioned as USS Jimetta -LRB- SP-878 -RRB- on 11 September 1917 at the New York Navy Yard at Brooklyn , New York , with Chief Boatswain 's Mate H. A. Holland , USNRF , in command .. New York. New York ( state ). commissioned. Ship commissioning. New York Navy Yard. New York Navy Yard. Brooklyn. Brooklyn, New York. USNRF. USNRF. Assigned to the 3rd Naval District , Jimetta served as a patrol and dispatch boat in Long Island Sound for the rest of World War I.. World War I. World War I. 3rd Naval District. 3rd Naval District. dispatch boat. dispatch boat. Long Island Sound. Long Island Sound. Jimetta was decommissioned on 11 December 1918 and returned to Studebaker the same day .. decommissioned. Ship decommissioning Answer:
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