With no explanation, label text_A→text_B with either "not_related" or "related".
text_A: France is a major military power in Europe.
text_B: Oxymorphazone is an opioid analgesic drug related to oxymorphone .. opioid. opioid. analgesic. analgesic. oxymorphone. oxymorphone. Oxymorphazone is a potent and long acting μ-opioid agonist which binds irreversibly to the receptor , forming a covalent bond which prevents it from detaching once bound .. opioid. opioid. μ-opioid. mu opioid receptor. agonist. agonist. covalent bond. covalent bond. This gives it an unusual pharmacological profile , and while oxymorphazone is only around half the potency of oxymorphone , with higher doses the analgesic effect becomes extremely long lasting , with a duration of up to 48 hours .. analgesic. analgesic. oxymorphone. oxymorphone. However , tolerance to analgesia develops rapidly with repeated doses , as chronically activated opioid receptors are rapidly internalised by β-arrestins , similar to the results of non-covalent binding by repeated doses of agonists with extremely high binding affinity such as lofentanil .. opioid. opioid. tolerance. tachyphylaxis. internalised. endocytosis. binding affinity. Dissociation constant. lofentanil. lofentanil
not_related.