[RESULTS] After adjustment by treatment , NLNi [ hazards ratio ( HR ) ( 1-3 vs 0 ) 3.5 , 95 % confidence interval ( CI ) : 2.3-5 .5 , and HR ( > 3 vs 0 ) 3.5 , 95 % CI : 2.0-6 .2 , P < 0.001 ] correlated with prognosis , whereas NLNr [ HR ( < 15 vs 15 ) 0.95 , 95 % CI : 0.6-1 .4 , P = 0.807 and HR ( < 23 vs 23 ) 1.4 , 95 % CI : 0.9-2 .0 , P = 0.131 ] did not .