[RESULTS] A 24-point BRAIN score was derived from INTERACT2 ( C-statistic , 0.73 ) based on baseline ICH volume ( mL per score , 10 = 0 , 10-20 = 5 , > 20 = 7 ) , recurrent ICH ( yes = 4 ) , anticoagulation with warfarin at symptom onset ( yes = 6 ) , intraventricular extension ( yes = 2 ) , and number of hours to baseline computed tomography from symptom onset ( 1 = 5 , 1-2 = 4 , 2-3 = 3 , 3-4 = 2 , 4-5 = 1 , > 5 = 0 ) predicted the probability of ICH growth ( ranging from 3.4 % for 0 point to 85.8 % for 24 points ) with good discrimination ( C-statistic , 0.73 ) and calibration ( Hosmer-Lemeshow P = 0.82 ) in INTERACT1 .