[RESULTS] For the HBeAg seroconversion , the rates of the LDT and LDT + ADV groups were 17.3 % and 23.1 % ( X2 = 0.71 ) at week 24 , 29.3 % and 30.8 % ( X2 = 0.03 ) at week 48 , 42.7 % and 40.0 % ( X2 = 0.10 ) at week 96 , 55.0 % and 43.3 % ( X2 = 1.08 ) at week 144 , 55.8 % and 66.7 % ( X2 = 0.45 ) at week 192 , and 63.3 % and 66.7 % at week 240 ; however , pairwise comparison showed no statistically significant differences between the groups ( P more than 0.05 ) .