Source: http://www.google.com/patents/US7264858?dq=7,013,345/
Timestamp: 2017-05-28 11:45:49
Document Index: 639467629

Matched Legal Cases: ['art 5', 'art 4', 'art 11', 'art 10', 'art 11', 'art 6']

Patent US7264858 - Multilayered articles having biocompatibility and biostability characteristics - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsMultilayer articles, such as tubing and films, are disclosed which have a soft layer of aliphatic polyurethane and at least one layer of hard aliphatic polyurethane. The articles formed avoid the problem of tackiness when using only a soft aliphatic polyurethane, while maintaining flexibility. The articles...http://www.google.com/patents/US7264858?utm_source=gb-gplus-sharePatent US7264858 - Multilayered articles having biocompatibility and biostability characteristicsAdvanced Patent SearchTry the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents.Publication numberUS7264858 B2Publication typeGrantApplication numberUS 10/694,681Publication dateSep 4, 2007Filing dateOct 28, 2003Priority dateOct 29, 2002Fee statusPaidAlso published asUS7588707, US20040131863, US20070292649, WO2004039584A1, WO2004039584A8Publication number10694681, 694681, US 7264858 B2, US 7264858B2, US-B2-7264858, US7264858 B2, US7264858B2InventorsBrian Peter Belliveau, Robert Bruce DownieOriginal AssigneeLubrizol Advanced Materials, Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (23), Non-Patent Citations (6), Referenced by (12), Classifications (41), Legal Events (5) External Links: USPTO, USPTO Assignment, EspacenetMultilayered articles having biocompatibility and biostability characteristics
US 7264858 B2Abstract
1. A multilayered tube consisting essentially of:
a first layer of soft aliphatic polyether polyurethane having an inner and outer surface, wherein said soft aliphatic polyether polyurethane has a Shore hardness from about 40 A to about 95 A as measured according to ASTM D2240; and
at least one second layer of hard aliphatic polyurethane selected from the group consisting of polyether polyurethane and polycarbonate polyurethane on at least one of said inner and outer surface of said first layer, wherein said hard aliphatic polyurethane has a Shore hardness from about 95 A to about 85 D as measured according to ASTM D2240, with the proviso that if said hard aliphatic polyurethane is a polycarbonate polyurethane, said Shore hardness of said hard aliphatic polyurethane is from about 70 A to about 80 D; and wherein both of said soft aliphatic polyurethane and said hard aliphatic polyurethane are biocompatible and biostable.
2. The multilayered tube of claim 1, wherein said soft aliphade polyurethane has a Shore hardness of from about 65 A to about 85 A.
3. The multilayered tube of claim 1, wherein said hard aliphatic polyurethane has a Shore hardness of from about 40 D to about 75 D).
4. The multilayered tube of claim 1, wherein said tube has said second layer of hard aliphatic polyurethane on said outer surface of said first layer of soft aliphatic polyurethane.
5. The multilayer tube of claim 4, wherein said rube is a profile tube.
6. The multilayer tube of claim 1, wherein said tube has said second layer of hard aliphatic polyurethane on said inner surface of said first layer of soft aliphatic polyurethane.
7. The niultilayer tube of claim 1, wherein said tube has said second layer of hard aliphatic polyurethane on both said inner and outer surface of said first layer of soft aliphatic polyurethane.
8. The muhilayer tube of claim 1, wherein bath of said soft and said hard aliphatic polyurethane is a polyether polyurethane.
9. The niultilayer tube of claim 1, wherein said polyether polyurethane is the reaction product of at least one polyether polyol with at least one alipharic diisocyanate and at least one glycol chain extender.
10. The multilayer tube of claim 9, wherein said aliphatic diisocyanate is selected from the group consisting of hexamethylene diisocyanate, isophorone diisocyanate, trimethyl hexamethylene diisocyanate, dicyclohexyl methane diisocyanate, and dimer acid diisocyanate.
11. The multilayer tube of claim 10, wherein said aliphatic diisocyanate is dicyclohexyl methane diisocyanate.
12. The multilayer tube of claim 9, wherein said glycol chain extender has from about 2 to about 10 carbon atoms.
13. The multilayer tube of claim 12, wherein said glycol chain extender is 1,4-butanediol.
14. The multilayer tube of claim 9, wherein said polyciher polyol is polytetramethylene ether glycol.
15. The niultilayer tube of claim 14, wherein said polytetrarnethylene ether glycol has a number avenge molecular weight of from about 500 to about 10,000.
16. The inultilayer tube of claim 15, wherein said potytetramethylene ether glycol has a number average molecular weight of from about 700 to about 3,000.
17. The multilayer tube of claim 1, wherein said bard aliphatie polyurethane is a polycarbonate polyurethane.
18. The multilayer tube of claim 17, wherein said polycarbonate polyurethane is the reaction product of at least one polycarbonate polyol with at least one aliphaxic diisocyanate and at least one glycol chain extender.
19. The multilayer tube of claim 18, wherein said polycarbonate polyol has a number average molecular weight of from about 500 to about 10,000.
20. The inultilayer tube of claim 19, wherein said polycarbonate polyol has a number average molecular weight of from about 500 to about 2,500.
21. The multilayer tube of claim 1, wherein the thickness of said at least one second layer of hard aliphatic polyurethane is from about 0.0001 to about 0.010 inch.
22. The multilayer tube of claim 21, wherein the thickness of said at least one second layer of hard aliphatic poiyurethane is from about 0.0005 to about 0.001 inch.
FIG. 1 is a diagram of a process for making an embodiment of the invention;
FIG. 2 is a cross-sectional view of a first embodiment of the invention showing a tube with an inner layer of soft polyurethane and an outer layer of hard polyurethane;
FIG. 3 is a cross-sectional view of a second embodiment of the invention showing a tube with an outer layer and inner layer of hard polyurethane with a layer of soft polyurethane between the two hard layers;
FIG. 4 is a cross-sectional view of a third embodiment of the invention showing a tube with an inner layer of hard polyurethane and an outer layer of soft polyurethane; and
FIG. 5 is a cross-sectional view of a fourth embodiment of the invention showing a profile tube having an outer layer of hard polyurethane and an inner layer of soft polyurethane.
At this point, the emulsion is preferably poured into a pan where it is allowed to flow to form uncured sheets. The pan with the sheets is then placed in an oven and heated at a temperature of at least 110° C. for four hours or more until the elastomer is cured. The sheets are then chopped up or pelletized in a standard pelletizer resulting in pellets approximately ¼ inch in length. These pellets are then used in machinery suitable for an extrusion of the desired product. Alternatively, the pellets may be dissolved in a solvent, such as dimethyl acetamide, tetrahydrofuran, 1,4 dioxane and m-pyrrol. The solution may then be used to make an article by a solvent casting method. These methods are further described in U.S. Pat. No. 4,441,590, the entire content of which is hereby incorporated by reference.
ISO 10993 - Part 5, (1999); Tests for in vitro
Medium (MEM) Elution
ISO 10993 - Part 4, (1992); Selection of tests
Systemic Injection Study
ISO 10993 - Part 11 (1993); Tests for
ISO 10993 - Part 10 (1995); Tests for
ISO 10993 - Part 11, (1993); Tests for
United States Pharmacopoeia 24, National
Formulary 19, pp. 1932-1933, 2000.
To demonstrate the biostability of the aliphatic polyurethanes used in this invention, the test used was the Implantation test, 2-week histopathology. The test was conducted in accordance with ISO Standards 10993—Part 6 (1994); tests for local effects after implantation.
Zone 1 330° F. ± 25° F. Zone 2 340° F. ± 25° F. Zone 3 350° F. ± 25° F. Zone 4 360° F. ± 25° F. Melt Temp. 360° F. ± 25° F. Die Temp. 360° F. ± 25° F. Pressure 1,000-2,500 psi Screen Pack 500 mesh The extruder heat zone temperatures and conditions for the hard layer is as follows:
360° F. ± 25° F.
370° F. ± 25° F.
380° F. ± 25° F.
390° F. ± 25° F.
2,000-4,000 psi
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS3411981Feb 24, 1966Nov 19, 1968Ind Vinyls IncMethod and article from laminating non-foamed polyurethane elastomer to vinyl polymer with a fusion bondUS4131731Jan 9, 1978Dec 26, 1978Beatrice Foods CompanyProcess for preparing polycarbonatesUS4211741Feb 8, 1978Jul 8, 1980Sunlite Plastics, Inc.Extrusion process for laminated medical-surgical tubingUS4303457 *Jun 18, 1979Dec 1, 1981Eaton CorporationMethod of making a semi-conductive paint hoseUS4447590Apr 4, 1983May 8, 1984Thermo Electron CorporationExtrudable polyurethane for prosthetic devices prepared from a diisocyanate, a polytetramethylene ether polyol and 1,4 butane diolUS4523005Apr 17, 1984Jun 11, 1985Thermedics, Inc.Extrudable polyurethane for prosthetic devices prepared from a diisocyanate, a polytetramethylene ether polyol, and 1,4-butane diolUS4789720 *Mar 9, 1988Dec 6, 1988Tyndale Plains-Hunter, Ltd.Hydrophilic polyurethanes prepared from mixed oxyalkylene glycolsUS4798597 *Apr 29, 1987Jan 17, 1989Sherwood Medical CoFlexible composite intubation tubeUS4874360Jul 1, 1988Oct 17, 1989Medical Engineering CorporationUreteral stent systemUS5449022Mar 30, 1994Sep 12, 1995Fresenius, A.G.Hose arrangement for a sealess centrifuge having hoses comprised of layers of different hardnessUS5712044Jun 5, 1995Jan 27, 1998Minnesota Mining And Manufacturing CompanyMedical device assemblies constructed from multilayered filmsUS5730919Nov 13, 1995Mar 24, 1998Minnesota Mining And Manufacturing CompanyMethod of forming multilayered barrier structuresUS5733619Jun 7, 1995Mar 31, 1998Baxter International Inc.Multilayer coextruded material for medical grade products and products made therefromUS5738902Oct 10, 1996Apr 14, 1998Cobe Laboratories, Inc.Biocompatible coated articleUS5738923May 16, 1995Apr 14, 1998Minnesota Mining And Manufacturing CompanyMedical tubing and assembliesUS5993436 *Nov 3, 1998Nov 30, 1999Terumo Kabushiki KaishaIndwelling catheter with improved kinking resistanceUS6127043Oct 23, 1996Oct 3, 2000Sengewald Verpackungen GmbhMultilayered sheet, process for the production thereof and use thereofUS6392002 *Dec 3, 1999May 21, 2002Acushnet CompanyUrethane golf ballUS6431219Feb 5, 2001Aug 13, 2002Alaris Medical Systems, Inc.Coextruded tubingDE4022741A1Jul 18, 1990Jan 23, 1992Basf AgMultilayer polyurethane film for prodn. of covering layers - comprises at least two layers of thermoplastic polyurethane with different shore hardnessDE20303982U1Mar 13, 2003May 15, 2003Rehau Ag & CoKatheter mit verbesserten GleiteigenschaftenGB2111067A Title not availableJPH02117403A Title not available* Cited by examinerNon-Patent CitationsReference1Article on "Biocompatibility/Biostability", Thermedics Polymer Products, a division of VIASYS Heathcare, no date, 9 pages.2Article on "Processing Information", Thermedics Polymer Products, a division of VIASYS Heathcare, Dec. 2001, pp. 1-7.3Article on "Technical Information", Thermedics Polymer Products, a division of VIASYS Healthcare, Dec. 2001, pp. 1-10.4Article on "Tecoflex MG Physical Test Data", Thermedics Polymer Products, a division of VIASYS Healthcare, no date, one page.5ASTM Designation D 2240-95, "Standard Test Method For Rubber Property-Durometer Hardness", 1995, pp. 403-406.6U. Frieden et al., NeoResins, The Netherlands, "New Development of Solvent Based Polyurethane Resins For Printing Inks", 6 pages.Referenced byCiting PatentFiling datePublication dateApplicantTitleUS8257719 *Mar 6, 2008Sep 4, 2012Ranir, LlcOral care layer and related method of manufactureUS8328760Jan 11, 2010Dec 11, 2012Angiodynamics, Inc.Occlusion resistant catheterUS8337451Oct 20, 2008Dec 25, 2012Angio Dynamics, Inc.Recirculation minimizing catheterUS8540663Jul 2, 2008Sep 24, 2013Navilyst Medical, Inc.High flow rate dialysis catheters and related methodsUS9050435Mar 22, 2011Jun 9, 2015Angiodynamics, Inc.High flow cathetersUS20080051759 *Aug 23, 2007Feb 28, 2008Boston Scientific Scimed, Inc.Polycarbonate polyurethane venous access devicesUS20080220032 *Mar 6, 2008Sep 11, 2008Ranir, LlcOral care layer and related method of manufactureUS20090012481 *Jul 2, 2008Jan 8, 2009Davey Christopher THigh Flow Rate Dialysis Catheters and Related MethodsUS20090187141 *Oct 20, 2008Jul 23, 2009Raymond LareauRecirculation minimizing catheterUS20100256546 *Apr 3, 2009Oct 7, 2010Davis Scott APolycarbonate Polyurethane Venous Access Devices Having Enhanced StrengthUS20110071500 *Sep 21, 2009Mar 24, 2011Navilyst Medical, Inc.Branched catheter tipUS20110172642 *Jan 11, 2010Jul 14, 2011Navilyst MedicalOcclusion Resistant Catheter* Cited by examinerClassifications U.S. Classification428/36.91, 428/423.3International ClassificationC08G18/75, B32B1/08, C08G18/48, F16L11/22, B32B27/40, A61L29/08, C08G18/44, B29C47/06, B29C47/00, F16L11/12Cooperative ClassificationY10T428/31554, Y10T428/31551, C08G18/4854, C08G18/44, B29C47/065, B32B27/40, C08G18/758, B29L2023/001, B29C47/26, B29C47/0004, F16L11/12, B32B1/08, Y10T428/1393, B29C47/0023, F16L11/22, B29K2075/00, B29C47/0021, A61L29/085, B29C47/0026European ClassificationA61L29/08B, B29C47/00J5, C08G18/44, B29C47/00B, C08G18/75D, F16L11/12, B32B1/08, C08G18/48H, B32B27/40, F16L11/22Legal EventsDateCodeEventDescriptionJan 12, 2004ASAssignmentOwner name: NOVEON IP HOLDINGS CORP., OHIOFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BELLIVEAU, BRIAN PETER;DOWNIE, ROBERT BRUCE;REEL/FRAME:014249/0698Effective date: 20031210Jul 19, 2006ASAssignmentOwner name: NOVEON, INC., OHIOFree format text: MERGER;ASSIGNOR:NOVEON IP HOLDINGS CORP.;REEL/FRAME:017957/0694Effective date: 20050630Jun 15, 2007ASAssignmentOwner name: LUBRIZOL ADVANCED MATERIALS, INC., OHIOFree format text: CHANGE OF NAME;ASSIGNOR:NOVEON, INC.;REEL/FRAME:019434/0322Effective date: 20070604Feb 24, 2011FPAYFee paymentYear of fee payment: 4Mar 4, 2015FPAYFee paymentYear of fee payment: 8RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services