Source: http://www.google.com/patents/US7776591?dq=6,034,652
Timestamp: 2016-02-13 00:55:11
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Matched Legal Cases: ['Application No. 04716880', 'Application No. 04716880', 'Application No. 04716880', 'Application No. 04716880', 'Application No. 04716880', 'Application No. 04716880', 'Application No. 2006']

Patent US7776591 - Hematopoietic stem cells treated by in vitro fucosylation and methods of use - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsA method of in vitro fucosylation of selectin ligands on cord blood-derived hematopoietic stem cells for bone marrow transplantation is disclosed. In this method, an effective amount of an α1,3-fucosyltransferase, e.g., α1,3-fucosyltransferase VI, is used in vitro to treat cord blood-derived hematopoietic...http://www.google.com/patents/US7776591?utm_source=gb-gplus-sharePatent US7776591 - Hematopoietic stem cells treated by in vitro fucosylation and methods of useAdvanced Patent SearchPublication numberUS7776591 B2Publication typeGrantApplication numberUS 11/448,359Publication dateAug 17, 2010Filing dateJun 7, 2006Priority dateApr 18, 2003Fee statusPaidAlso published asCA2522743A1, CA2522743C, CA2816907A1, EP1668109A2, EP1668109A4, EP1668109B1, EP2327760A2, EP2327760A3, EP2327760B1, US7332334, US8084255, US8633021, US20040209357, US20060228340, US20100150883, US20110097308, US20130251688, WO2004094619A2, WO2004094619A3Publication number11448359, 448359, US 7776591 B2, US 7776591B2, US-B2-7776591, US7776591 B2, US7776591B2InventorsLijun Xia, Rodger P. McEverOriginal AssigneeOklahoma Medical Research FoundationExport CitationBiBTeX, EndNote, RefManPatent Citations (13), Non-Patent Citations (36), Referenced by (4), Classifications (12), Legal Events (2) External Links: USPTO, USPTO Assignment, EspacenetHematopoietic stem cells treated by in vitro fucosylation and methods of use
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS5004681Nov 12, 1987Apr 2, 1991Biocyte CorporationPreservation of fetal and neonatal hematopoietic stem and progenitor cells of the bloodUS5192553Nov 10, 1988Mar 9, 1993Biocyte CorporationIsolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic useUS5858752Jun 7, 1995Jan 12, 1999The General Hospital CorporationFucosyltransferase genes and uses thereofUS6399337Jun 5, 1998Jun 4, 2002The Governors Of The University Of Albertaα1,3-fucosyltransferaseUS6440110Dec 18, 2000Aug 27, 2002Children's Hospital Medical Center Of Northern CaliforniaApparatus and method for collecting blood from an umbilical cordUS6461835Sep 3, 1999Oct 8, 2002The University Of OklahomaFucosyltransferases, polynucleotides encoding fucosyltransferases, and transgenic mammal incorporating sameUS6485722Feb 26, 1997Nov 26, 2002Regents Of The University Of MinnesotaMethod for selective engraftment of drug-resistant hematopoietic stem cellsUS7332334 *Jan 30, 2004Feb 19, 2008Oklahoma Medical Research FoundationHematopoietic stem cells treated by in vitro fucosylation and methods of useUS20030040607Oct 18, 2001Feb 27, 2003Robert SacksteinHematopoietic cell E-selection/L-selectin ligand polypeptides and methods of use thereofEP1668109A2Mar 3, 2004Jun 14, 2006Lijun XiaHematopoietic stem cells treated by in vitro fucosylation and methods of useWO1996040881A1May 8, 1996Dec 19, 1996The General Hospital CorporationFucosyltransferase genes and uses thereofWO2000006704A2Jul 20, 1999Feb 10, 2000Yeda Res & DevHematopoietic cell composition for use in transplantationWO2005017115A2Aug 11, 2004Feb 24, 2005Paul S FrenetteCord blood-derived hematopoietic progenitor cells* Cited by examinerNon-Patent CitationsReference1Da Silva et al., "Differences Amid Bone Marrow and Cord Blood Hematopoietic Stem/Progenitor Cell Divison Kinetics", Journal of Cellular Physiology, published online Mar. 10, 2009, Wiley InterScience (www.interscience.wiley.com), pp. 102-111.2Frenette et al., "Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow", Proc. Natl. Acad. Sci., USA, Nov. 1998, vol. 95, pp. 14423-14428, Medical Sciences.3Greenberg et al., "Relationship between selectin-mediated rolling of hematopoietic stem and progenitor cells and progression in hematopoietic development", Blood, pp. 478-486, vol. 95, No. 2, Jan. 15, 2000, XP002450253.4Grewel et al., "Unrelated donor hematopoietic cell transplantation: marrow or umbilical cord blood?" Blood, Jun. 1, 2003, vol. 101, No. 11, pp. 4233-4244.5Hao et al., "A functional comparison of CD34+CD38- cells in cord blood and bone marrow" Blood, Nov. 15, 1995, vol. 86, No. 10, pp. 3745-3753.6Harris et al., "Collection, separation and cryopreservation of umbilical cord blood for use in transplantation", Bone Marrow Transplantation, 1994, vol. 13, pp. 135-143.7Hidalgo et al "Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow" Blood, 2005, vol. 105, No. 2, pp. 567-575.8Hidalgo et al., "Functional selectin ligands mediating human CD34+ cell interactions with bone marrow endothelium are enhanced postnatally", The Journal of Clinical Investigation, Aug. 2002, vol. 110, No. 4, pp. 559-569.9Katayama et al. "PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and alpha4 integrin" Blood, 2003, vol. 102, No. 6, pp. 2060-2067.10Katayama et al. "PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and α4 integrin" Blood, 2003, vol. 102, No. 6, pp. 2060-2067.11Kobzdej et al., "Discordant expression of selectin ligands and sialyl Lewis x-related epitopes on murine myeloid cells", Blood, Dec. 15, 2002, vol. 100, No. 13, pp. 4485-4494.12Li et al., "Post-translational Modifications of Recombinant P-selectin Glycoprotein Ligand-1 Required for Binding to P- and E-selectin", Journal of Biological Chemistry, pp. 3255-3264, vol. 271, No. 6, Issue of Feb. 6, 1996, XP002116305.13Mazo et al., "Hematopoietic Progenitor Cell Rolling in Bone Marrow Microvessels: Parallel Contributions by Endothelial Selectins and Vascular Cell Adhesion Molecule 1", J. Exp. Med., Aug. 3, 1998, vol. 188, No. 3, pp. 465-474.14McEver et al., "Perspectives Series: Cell Adhesion in Vascular Biology", J. Clin. Invest., Aug. 1997, vol. 100, No. 3, pp. 485-492.15Nishihira et al., "The Japanese cord blood bank network experience with cord blood transplantation from unrelated donors for haematological malignancies: an evaluation of graft-versus-host disease prophylaxis", British Journal of Haematology, 2003, vol. 120, pp. 516-522.16PCT/US04/06474, Search Report, Dec. 5, 2006.17Ramachandran et al., "Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow", Proc. Natl. Acad. Sci., Aug. 28, 2001, vol. 98, No. 18, pp. 10166-10171.18Rini et al., "Glycosyltransferases and Glycan-processing Enzymes" Essentials of Glycobiology, Second Edition, published by Cold Spring Harbor Laboratory Press, cold Spring Harbor, New York, 2009 by The Consortium of Glycobiology Editors, La Jolla, California, pp. 63-73.19Rocha et al., "Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia", Blood, May 15, 2001, vol. 97, No. 10, pp. 2962-2971.20Snapp et al., "P-Selectin Glycoprotein Ligand-1 Is Essential for Adhesion to P-Selectin But Not E-Selectin in Stably Transfected Hematopoietic Cell Lines", Blood, vol. 89, No. 3 (Feb. 1, 1997), pp. 896-901.21Stevens et al., "Placental/umbilical cord blood for unrelated-donor bone marrow reconstitution: relevance of nucleated red blood cells", Blood, Oct. 1, 2002, vol. 100, No. 7, pp. 2662-2664.22Terstappen et al., "Sequential Generations of Hematopoietic Colonies Derived From Single Nonlineage-Committed CD34+ CD38- Progenitor Cells", Blood, Mar. 15, 1991, vol. 77, No. 6, pp. 1218-1227.23Terstappen et al., "Sequential Generations of Hematopoietic Colonies Derived From Single Nonlineage-Committed CD34+ CD38− Progenitor Cells", Blood, Mar. 15, 1991, vol. 77, No. 6, pp. 1218-1227.24Theunissen et al., "A multifactorial analysis of umbilical cord blood, adult bone marrow and mobilized peripheral blood progenitors using the improved ML-IC assay" Experimental Hematology, vol. 33, (2005) pp. 165-172.25Thomas, "History, Current Results, and Research in Marrow Transplantation", Perspectives in Biology and Medicine, Winter 1995, vol. 38, No. 2, pp. 230-237.26Van Den Oudenrigin et al., "Differences in megakaryocyte expansion potential between CD34+ stem cells derived from cord blood, peripheral blood, and bone marrow from adults and children" Experimental Hematology, vol. 28, (2000) pp. 1054-1061.27Wagers et al., "Interleukin 12 and Interleukin 4 Control T Cell Adhesion to Endothelial Selectins through Opposite Effects on alpha 1,3-fucosyltransferase VII Gene Expression", J. Exp. Med., Dec. 21, 1998, vol. 188, No. 12, pp. 2225-2231.28Wagers et al., "Interleukin 12 and Interleukin 4 Control T Cell Adhesion to Endothelial Selectins through Opposite Effects on α 1,3-fucosyltransferase VII Gene Expression", J. Exp. Med., Dec. 21, 1998, vol. 188, No. 12, pp. 2225-2231.29Xia et al., European Patent Application No. 04716880.2-2405, "Hematopoietic Stem Cells Treated by In Vitro Fucosylation and Methods of Use" Office Action mailed Aug. 3, 2009, 6 pgs.30Xia et al., European Patent Application No. 04716880.2-2405, "Hematopoietic Stem Cells Treated by In Vitro Fucosylation and Methods of Use" Office Action mailed Mar. 28, 2008, 6 pgs.31Xia et al., European Patent Application No. 04716880.2-2405, "Hematopoietic Stem Cells Treated by In Vitro Fucosylation and Methods of Use" Office Action mailed Nov. 25, 2008, 4 pgs.32Xia et al., European Patent Application No. 04716880.2-2405, "Hematopoietic Stem Cells Treated by In Vitro Fucosylation and Methods of Use" Response mailed Feb. 9, 2010, 7 pgs.33Xia et al., European Patent Application No. 04716880.2-2405, "Hematopoietic Stem Cells Treated by In Vitro Fucosylation and Methods of Use" Response mailed Jun. 5, 2009, 4 pgs.34Xia et al., European Patent Application No. 04716880.2-2405, "Hematopoietic Stem Cells Treated by In Vitro Fucosylation and Methods of Use" Response mailed Oct. 7, 2008, 9 pgs.35Xia et al., Japanese Patent Application No. 2006-509036, "Hematopoietic Stem Cells Treated by In Vitro Fucosylation and Methods of Use" Office Action mailed Jan. 6, 2010, 6 pgs (2 pgs in Japanese; 4 pgs in English Translation).36Yasui, et al., "Differences Between Peripheral Blood and Cord Blood in the Kinetics of Lineage-Restricted Hematopoietic Cells: Implications for Delayed Platelet Recovery Following Cord Blood Transplantation" Stem Cells vol. 21 (2003) pp. 143-151.Referenced byCiting PatentFiling datePublication dateApplicantTitleUS8084255 *Feb 17, 2010Dec 27, 2011Oklahoma Medical Research FoundationStem cells treated by in vitro fucosylation and methods of useUS8633021Nov 17, 2010Jan 21, 2014Oklahoma Medical Research FoundationStem cells treated by in vitro fucosylation and methods of useUS20100150883 *Feb 17, 2010Jun 17, 2010Lijun XiaStem cells treated by in vitro fucosylation and methods of useUS20110097308 *Apr 28, 2011Lijun XiaStem cells treated by in vitro fucosylation and methods of use* Cited by examinerClassifications U.S. Classification435/366, 435/375, 435/372International ClassificationA61K35/12, C12N5/0789, C12N5/00Cooperative ClassificationA61K2035/124, C12N5/0647, C12N5/0006, A61K35/28European ClassificationC12N5/06B11P, C12N5/00BLegal EventsDateCodeEventDescriptionDec 21, 2010CCCertificate of correctionJan 13, 2014FPAYFee paymentYear of fee payment: 4RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services