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Patent US8048999 - Nuclear reprogramming factor - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign in<nobr>Advanced Patent Search</nobr>PatentsThere is provided a nuclear reprogramming factor for a somatic cell, which comprises a gene product of each of the following three kinds of genes: an Oct family gene, a Klf family gene, and a Myc family gene, as a means for inducing reprogramming of a differentiated cell to conveniently and highly reproducibly...http://www.google.com/patents/US8048999?utm_source=gb-gplus-sharePatent US8048999 - Nuclear reprogramming factorAdvanced Patent SearchPublication numberUS8048999 B2Publication typeGrantApplication numberUS 12/086,479Publication dateNov 1, 2011Filing dateDec 6, 2006Priority dateDec 13, 2005Also published asCA2632142A1, CA2632142C, CN101356270A, CN101356270B, CN101864392A, CN103113463A, CN103773804A, EP1970446A1, EP1970446A4, EP1970446B1, EP2206724A1, EP2206778A1, EP2208786A1, US20090068742, WO2007069666A1Publication number086479, 12086479, US 8048999 B2, US 8048999B2, US-B2-8048999, US8048999 B2, US8048999B2InventorsShinya Yamanaka, Kazutoshi Takahashi, Keisuke OkitaOriginal AssigneeKyoto UniversityExport CitationBiBTeX, EndNote, RefManPatent Citations (99), Non-Patent Citations (447), Referenced by (11), Classifications (17), Legal Events (2) External Links: USPTO, USPTO Assignment, EspacenetNuclear reprogramming factorUS 8048999 B2Abstract There is provided a nuclear reprogramming factor for a somatic cell, which comprises a gene product of each of the following three kinds of genes: an Oct family gene, a Klf family gene, and a Myc family gene, as a means for inducing reprogramming of a differentiated cell to conveniently and highly reproducibly establish an induced pluripotent stem cell having pluripotency and growth ability similar to those of ES cells without using embryo or ES cell.
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WasielewskiEnhanced medical implant comprising disrupted tooth pulp and tooth particlesUS8497124May 7, 2012Jul 30, 2013Factor Bioscience Inc.Methods and products for reprogramming cells to a less differentiated stateUS8540978May 3, 2010Sep 24, 2013Ray C. WasielewskiTreatment composition comprising physically disrupted tooth pulp and non-cultured stem cells in a matrixUS8562969May 3, 2010Oct 22, 2013Ray C. WasielewskiTreatment composition comprising physically disrupted tooth pulp and non-cultured stem cellsUS8748179Jun 23, 2010Jun 10, 2014Osaka UniversityMethod for efficient production of induced pluripotent stem cells utilizing cells derived from oral mucosaUS20100021437 *Apr 6, 2009Jan 28, 2010The McLean Hospital Corporation Whitehead Institute for Biomedical ResearchNeural stem cells derived from induced pluripotent stem cellsUS20110200568 *Aug 10, 2009Aug 18, 2011Yasuhiro IkedaInduced pluripotent stem cellsUS20120129172 *May 28, 2010May 24, 2012Kyoto UniversityMethod for selecting clone of induced pluripotent stem cellsUS20120263689 *Sep 10, 2010Oct 18, 2012The Salk Institute For Biological StudiesAdipose-derived induced pluripotent stem cellsWO2014011813A1Jul 10, 2013Jan 16, 2014Tissuetech, Inc.Compositions containing hc-ha/ptx3 complexes and methods of use thereof* Cited by examinerClassifications U.S. Classification536/23.5, 530/350, 435/377International ClassificationC12N5/074, C07H21/04Cooperative ClassificationC12N2501/606, C12N2501/60, C12N2501/604, C12N2501/603, C12N2501/602, C12N2501/605, C12N5/0696, C07K14/4702, C12N2799/027, C12N2510/00European ClassificationC07K14/47A1, C12N5/06B45Legal EventsDateCodeEventDescriptionSep 4, 2012CCCertificate of correctionSep 29, 2008ASAssignmentOwner name: KYOTO UNIVERSITY, JAPANFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:YAMANAKA, SHINYA;REEL/FRAME:021600/0676Effective date: 20080814RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google