Source: http://www.google.com/patents/US20040073161?dq=5166694
Timestamp: 2014-07-30 01:28:11
Document Index: 210143600

Matched Legal Cases: ['art 2', 'art 10', 'art 10', 'art 10', 'art 10', 'art 11', 'art 11', 'art 11', 'art 10', 'art 11']

Patent US20040073161 - Syringe pump, and liquid feeding method - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign in<nobr>Advanced Patent Search</nobr>PatentsA syringe pump adapted to inject a liquid medicine in the syringe according to a predetermined infusion pattern, comprising a syringe diameter detecting means for detecting the volume of the syringe, an infusion pattern input means for inputting an infusion pattern, an occlusion pressure setting means,...http://www.google.com/patents/US20040073161?utm_source=gb-gplus-sharePatent US20040073161 - Syringe pump, and liquid feeding methodAdvanced Patent SearchPublication numberUS20040073161 A1Publication typeApplicationApplication numberUS 10/468,798PCT numberPCT/JP2002/001460Publication dateApr 15, 2004Filing dateFeb 20, 2002Priority dateFeb 22, 2001Also published asDE60235964D1, EP1362606A1, EP1362606A4, EP1362606B1, WO2002066102A1Publication number10468798, 468798, PCT/2002/1460, PCT/JP/2/001460, PCT/JP/2/01460, PCT/JP/2002/001460, PCT/JP/2002/01460, PCT/JP2/001460, PCT/JP2/01460, PCT/JP2001460, PCT/JP2002/001460, PCT/JP2002/01460, PCT/JP2002001460, PCT/JP200201460, PCT/JP201460, US 2004/0073161 A1, US 2004/073161 A1, US 20040073161 A1, US 20040073161A1, US 2004073161 A1, US 2004073161A1, US-A1-20040073161, US-A1-2004073161, US2004/0073161A1, US2004/073161A1, US20040073161 A1, US20040073161A1, US2004073161 A1, US2004073161A1InventorsYasuharu TachibanaOriginal AssigneeYasuharu TachibanaExport CitationBiBTeX, EndNote, RefManReferenced by (9), Classifications (12), Legal Events (1) External Links: USPTO, USPTO Assignment, EspacenetSyringe pump, and liquid feeding methodUS 20040073161 A1Abstract A syringe pump adapted to inject a liquid medicine in the syringe according to a predetermined infusion pattern, comprising a syringe diameter detecting means for detecting the volume of the syringe, an infusion pattern input means for inputting an infusion pattern, an occlusion pressure setting means, a pusher position calculating means, and a drive control means for drive-controlling a motor on the basis of an inputted infusion pattern to push the pusher of the syringe so as to infuse the liquid medicine in the syringe, and characterized in that the pusher position is calculated on the basis of the set-inputted infusion pattern and the occlusion detection level is automatically changed according to the pusher position. Images(7) Claims(6)
BRIEF DESCRIPTION OF DRAWINGS [0007]FIG. 1 is an external perspective view of a syringe pump 1 of the invention; [0008]FIG. 2(a) is an external perspective view showing how a syringe S is set in a syringe pump 1, and FIG. 2(b) is an external perspective view to explain the operation of a clamp 5 which detachably holds a syringe S in a syringe pump 1 in an immobile state; [0009]FIG. 3 is a front view showing a rough construction of a slider mechanism which drives a slider assembly 50; [0010]FIG. 4 is a plan view of an operating panel part 2 f; [0011]FIG. 5 is a flow chart showing blockage detection; and [0012]FIG. 6 is a block diagram of a syringe pump of the invention.
[0095] where LNE (cm) is the alarm position, R (mL/h) is the infusion rate, T (h) is remaining time and A (cm2) is the syringe sectional area. As a result of the foregoing, the movement of the piston SK of the syringe S can be accurately controlled. [0096] The comparison operation of a predicted alarm position for the pusher is performed as described above (Step S9). When the pusher reaches the predicted alarm position, an alarm (a warning) is given. When the pusher reaches the push-finish position LE (cm), the threshold value of occlusion detection is automatically changed by the threshold value level changing means 110 (Step S10). After that, the action indicator 7 blinks (lights up) red, thereby giving an alarm (Step S11) and the liquid infusion (administration) is completed (Step S12). [0097] Incidentally, if injection is not started even when about two minutes pass after the completion of flow rate setting after the setting of a syringe S in the main body 1, the buzzer sounds to make a forgotten start known to the user. In this case, the buzzer stops sounding when the stop/mute switch 28 is pressed. When an infusion pattern (a flow rate) is to be changed during infusion, the infusion is stopped by performing temporary stop of infusion and after that, resetting is performed by use of the setting input means 60 including the setting dial 6. At this time, the action indicator 7 goes off when the stop/mute switch 28 is pressed. [0098] When the infusion of a liquid medicine in a predetermined amount is completed, the stop condition is ascertained and the syringe is removed. For this purpose, the clamp 5 is drawn upward and then held in a condition turned by about 90 degrees. Subsequently, the clutch lever 52 of the slider assembly 50 is pressed and the syringe is removed by opening the right and left hook members. After that, when the syringe pump is not used again, the power switch 15 is cut off by being continuously pressed for not less than about 2 seconds. [0099] This syringe pump can also be applied to a case where product information, such as a syringe maker, a syringe diameter (capacity), medicine type, contained in a bar code and an IC chip applied to the syringe is automatically read by use of reading means (not shown). [0100] Now injection per body weight will be described. First, the unit changeover switch (serving also as a display on/off switch) 10 a is continuously pressed for not less than 2 seconds, the above-described infusion setting display part 10 lights up and it becomes possible to perform infusion (gamma infusion) per body weight. Subsequently, the display screen of the infusion setting display part 10 changes when the item changeover switch 10 b is pressed, and each time the item changeover switch 10 b is pressed, an infusion rate (an injected amount) per body weight, body weight, an amount of medicine and an amount of solution are displayed in a blinking manner. Areas where the display is blinking are items whose settings can be changed. Therefore, by turning the setting dial 6 with a desired item kept displayed, numeric values are changed by changing the numeric values on the screen of the infusion setting display part 10. Furthermore, it is possible to rapidly change each step value by turning the setting dial 6 while pressing the stop/mute switch 28. The screen of this gamma infusion setting display part 10 is constructed in such a manner that a flow rate (an infusion rate) is automatically calculated and displayed according to the set infusion amount per body weight, body weight, amount of medicine and amount of solvent. [0101] For the setting of special functions, the operation of a changeover switch built in the interior of the main body enables the setting of various modes to be changed as required. As these special functions, predetermined amounts in the display part 11 of a flow rate, predetermined amount and integrated amount can be changed between a standard mode and a predetermined amount mode. In the standard mode, each time the display changeover switch 26 is pressed, a flow rate and an integrated amount are displayed in this order and it is impossible to set a predetermined amount. [0102] Furthermore, when a changeover switch to the predetermined mode is made by operating the changeover built in the interior of the main body, the display of the display part 11 appears in the order of flow rate, predetermined amount and integrated amount, and it becomes possible to set a predetermined amount. In this setting of a predetermined amount, the predetermined amount lamp 24 is first caused to light up by pressing the display changeover switch 26 and a predetermined amount is then set by turning the setting dial 6. This setting can be changed in 0.1 ml steps. In a case where a predetermined amount is set and injection is started, the predetermined amount lamp 24 blinks and the buzzer sounds when an integrated amount has reached the predetermined amount. [0103] In a case when the setting of a predetermined amount has been performed in this way, the injection of a liquid medicine is continued at a flow rate (an infusion rate) of 0.1 ml/h when the KOR (keep open rate) function works. When the user wants to perform confirmation, the action indicator 7 lights up by the pressing of the stop/mute switch 28 and the buzzer stops sounding. At this time, the keep vein open function continues. When the stop/mute switch 28 is pressed again, the action indicator 7 goes off, the keep vein open function is canceled and comes to a stop condition, and injection in the predetermined amount mode is finished. [0104] A re-alarm permits a change to the standard mode and the mute mode. Specifically, it is possible to set the standard mode with the action indicator 7 blinking red with the buzzer enabled in which when an alarm condition is not canceled for not less than 2 minutes after the buzzer extinguished, the buzzer is caused to sound again; and the mute mode in which the re-alarm function does not to work even when an alarm condition continues for not less than 2 minutes. [0105] A forgotten start alarm permits a change to the standard mode and the mute mode. Specifically, it is possible to set the standard mode with the action indicator 7 blinking red with the buzzer enabled in which when a stop condition continues for not less than 2 minutes in a state permitting a start, the buzzer sounds thereby to make a forgotten start known to the user; and the mute mode in which the forgotten start alarm function does not work even when a stop condition continues for not less than 2 minutes. [0106] A change of a syringe maker name is made possible by use of the built-in changeover switch. However, it is ensured that usually, the setting of this special function cannot be performed, because a trouble might be caused if this function is carelessly performed. [0107] In changing the setting of the sound volume of the buzzer, the stop/mute switch 28 is continuously pressed and the integrating clearing switch 27 is pressed at the same time. Then, �bEL *2� appears on the display part 11 of flow rate, predetermined amount and integrated amount and the setting mode begins. With the stop/mute switch 28 kept pressed, the integrating clearing switch 27 is released and pressed and the display changes to �bEL : 1,� �bEL : 2,� and �bEL : 3� according to �large,� �medium,� and �small� of the volume of the buzzer. Therefore, when a desired sound volume is obtained, the user's fingers are released from all switches, whereby the setting of the volume of the buzzer is performed. [0108] The syringe pump can also be operated by use of a DC power source in a centralized power source box. In this case, it is ascertained that an AC power cable is detached from the main body 1 and a DC cable is then connected to a DC connector 9 on the right side surface of the main body. Subsequently, the AC/DC lamp 16 lights up and power is supplied from the DC power source when the power switch 15 is turned on. [0109] When power is supplied neither from the AC power source nor from the DC power source, power supply is automatically changed over to the built-in battery, the AC/DC lamp 16 goes off and the syringe pump can be continuously used for about 3 hours using the built-in battery. Regardless of the on/off state of the power source, the built-in battery can be charged when the AC power source or the DC power source is connected. During this charging the battery lamp 17 lights up and displays the remaining amount of the battery at three levels. A rough standard for the remaining amount of the battery is such that use for not less than about 160 minutes is possible when all the three lamps are on, the action time is for not less than 80 minutes when two lamps are on, and use for not less than 30 minutes is possible when only one lamp is on. A case where all the three lamps blink and a case where two lamps or only one lamp lights up indicate that the battery has deteriorated. [0110] When the remaining amount of the battery decreases further, the battery alarm lamp 22 blinks and the buzzer sounds. Accordingly, the syringe pump is rapidly connected to the AC or DC power source and used. [0111] For an electrostatic noise margin, to prevent a malfunction by contact discharge at �8 kV and aerial discharge at �15 kV, this syringe pump is constructed so as to conform to the overseas standards: FCC Prat. 18, CISPR 11, IEC 60601-1-2, IEC 60601-2-24, and VDEDIN57871. The electric shockproof type for TYPE CY (ground leakage current: not more than 0.5 mA) in CLASS I (not less than 3 kV) conforms to the domestic standard JIS T1001 and T1002 and the overseas standard IEC 60601-1. [0112] For chemical resistance, wiping off with alcohol is prohibited by operating instructions. However, in order to give the syringe pump chemical resistance to alcohol and similar substances, the outer layer is given ABS grade V0 and measures are taken by performing under printing, for example, so that a nameplate, printed characters, indications, etc. do not disappear. [0113] The driving thrust (the force which pushes the pusher) is about 15 kg�f maximum and the syringe pump is constructed so as to withstand about 20 kg�f. The mechanical (feed) accuracy can be maintained at high accuracies of within �1% by actual measurement and ensured for each syringe type of various syringe makers. [0114] Concretely, by measuring the moving distance of the slider assembly 50, the mechanical (feed) accuracy was set as follows: [0115] (A) Flow (infusion) rate<1.0 ml/h [0116] 60 minutes (long-term): Not more than �5% [0117] (B) 1.0 ml/h≦flow rate<5.0 ml/h [0118] 2-minute observation from the observation window: Not more than �2% [0119] and at the same time [0120] 60 minutes (long-term): Not more than �1% [0121] (C) 5.0 ml/h≦flow rate [0122] 2-minute observation from the observation window: Not more than �1% [0123] Discharge rates were measured so that high flow (infusion) rate accuracies of within �3% can be ensured for each syringe type of various syringe makers. [0124] (A) 1.0 ml/h≦flow rate<5.0 ml/h [0125] 2-minute observation from the observation window: Not more than �5% [0126] (B) 1.0 ml/h≦flow rate 60 minutes (long-term): Not more than �3% [0127] (C) It was ascertained that not less than 95% is ensured for the 10 minutes after the start of infusion. [0128] The display part 10 of an injected amount per body weight is a liquid crystal provided with a back light (yellow or green). This is a numeral indicator composed of seven segments. This display part can display weight in kg, an amount of medicine in mg, an amount of solution in ml, a dose in μg/kg/min or mg/kg/h, etc.; body weight is indicated in 4 digits by the seven segments+a decimal point by one segment; an amount of medicine is indicated in 4 digits by the seven segments+a decimal point by one segment; an amount of solution is indicated in 4 digits by the seven segments+a decimal point by one segment; and a dose is indicated in 4 digits by the seven segments+a decimal point by one segment. Usually, when the ordinary infusion mode is selected, the back light goes off for the whole screen. [0129] The display part 11 of flow rate, integrated amount and predetermined amount is a readily seen LED display, which performs display in 4 digits by seven segments+a decimal point by one segment, changes over automatically to a flow rate display during the setting of the γ mode. Furthermore, during the setting of the mode for injection per weight body (in μg/kg/min or mg/kg/h, etc.) this display part whose flow rate indication changes sequentially in response to a set value is indicated, changes over automatically to a flow rate display if the display part is left as it is for about 15 seconds when an integrated amount or a predetermined amount. [0130] Alarms are given in the case of Er*, an out-of-control CPU, a switch operation and self-check. These alarms are generated in a readily perceived sound free from unpleasant feeling and conform to overseas standards and a changeover at three levels of sound volume (panel operation) is possible. Set sound volume can be stored and the levels of sound volume can be displayed during setting. The maximum sound volume is not less than 65 dB at a distance of 1 m. Furthermore, the alarm system is of the self-excitation type (which gives an alarm in the case of an out-of-control CPU). [0131] The tone quality of the alarms is 3 frequencies (2 to 4 kHz or so). PWM output from the CPU is possible and the following is ensured: alarm→PWM output, watch dog→hardware oscillation. The procedure for sound volume changeover is as follows. (1) In the case of an alarm state (excepting a voltage drop and a remaining amount), a changeover is impossible and the integrating clearing switch is pushed. (2) Each time the integrating clearing switch is pushed, with the stop switch kept pressed, a change occurs from medium→large→small→medium . . . (the buzzer makes a sound for 1.5 seconds). (3) In synchronization with the buzzer, the following appears in the flow rate display part in 7 segments: medium=�b-2,� large=�b-3� and small=�b-1.� (4) The result is written in E2PROM. [0132] As described above, in a syringe pump and a liquid infusing method according to the invention, by utilizing the characteristic that a detected occlusion value transmitted to the pusher increases beyond a position at which the infusing of a liquid medicine in the syringe is completed, it becomes easy to accurately detect a position at which the infusing of a liquid medicine in the syringe is completed by combining pusher position detection means and occlusion detection means. That is, when a remaining amount decreases beyond a position at which the infusion of a liquid medicine in the syringe is completed, a detected occlusion value transmitted to the pusher increases and this position at which the infusion of a liquid medicine in the syringe is completed may not sometimes be accurately detected. Therefore, a push-finish position until the remaining amount in the syringe is injected can be accurately found by finding the push-finish position from an arithmetic expression by setting a position in which a remaining amount is small as an alarm position, setting an occlusion detection level at a low level and ensuring that the pusher is moved by a slider from the alarm position. Referenced byCiting PatentFiling datePublication dateApplicantTitleUS7153290 *Jul 30, 2003Dec 26, 2006Atom Medical CorporationSyringe pumpUS7905860 *Sep 5, 2008Mar 15, 2011Elixir Corp.Plunger disc loading mechanism for syringe pumpUS8378837 *Feb 18, 2010Feb 19, 2013Hospira, Inc.Occlusion detection systemUS8663161 *Apr 22, 2011Mar 4, 2014Acacia, Inc.Neonatal fluid tubing heaterUS20100214110 *Feb 18, 2010Aug 26, 2010Hospira, Inc.Occlusion detection systemUS20110184383 *Apr 6, 2011Jul 28, 2011Terumo Kabushiki KaishaSyringe pumpUS20120271271 *Apr 22, 2011Oct 25, 2012Hyun Dongchul DNeonatal fluid tubing heaterEP1951355A2 *Nov 16, 2006Aug 6, 2008ACIST Medical Systems, Inc.Medical fluid injection systemWO2010096602A1 *Feb 19, 2010Aug 26, 2010Hospira, Inc.Occlusion detection system* Cited by examinerClassifications U.S. Classification604/67, 604/151, 604/131International ClassificationA61M5/168, A61M5/145Cooperative ClassificationA61M5/1456, A61M5/1684, A61M5/1458, A61M5/16854, A61M2205/3393, A61M2205/3379European ClassificationA61M5/145B10Legal EventsDateCodeEventDescriptionAug 22, 2003ASAssignmentOwner name: TERUMO KABUSHIKI KAISHA, JAPANFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:TACHIBANA, YASUHARU;REEL/FRAME:014777/0755Effective date: 20030801RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google