Source: http://www.google.com/patents/US7486991?dq=7,013,345/
Timestamp: 2016-08-26 00:47:43
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Matched Legal Cases: ['application No. 10', 'application No. 10', 'application No. 10', 'application No. 10', 'application No. 10', 'application No. 10', 'application No. 10', 'application No. 10', 'application No. 10', 'application No. 10', 'application No. 10']

Patent US7486991 - Baroreflex modulation to gradually decrease blood pressure - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsAn aspect of the present subject matter relates to a baroreflex stimulator. An embodiment of the stimulator includes a pulse generator to provide a baroreflex stimulation signal through an electrode, and a modulator. The modulator modulates the baroreflex stimulation signal to increase the baroreflex...http://www.google.com/patents/US7486991?utm_source=gb-gplus-sharePatent US7486991 - Baroreflex modulation to gradually decrease blood pressureAdvanced Patent SearchPublication numberUS7486991 B2Publication typeGrantApplication numberUS 10/746,845Publication dateFeb 3, 2009Filing dateDec 24, 2003Priority dateDec 24, 2003Fee statusPaidAlso published asUS8321023, US8626282, US20050149131, US20090143838, US20130079838, US20140121729Publication number10746845, 746845, US 7486991 B2, US 7486991B2, US-B2-7486991, US7486991 B2, US7486991B2InventorsImad Libbus, Julio C. SpinelliOriginal AssigneeCardiac Pacemakers, Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (106), Non-Patent Citations (93), Referenced by (146), Classifications (11), Legal Events (4) External Links: USPTO, USPTO Assignment, EspacenetBaroreflex modulation to gradually decrease blood pressure
US 7486991 B2Abstract
An aspect of the present subject matter relates to a baroreflex stimulator. An embodiment of the stimulator includes a pulse generator to provide a baroreflex stimulation signal through an electrode, and a modulator. The modulator modulates the baroreflex stimulation signal to increase the baroreflex stimulation therapy by a predetermined rate of change to lower systemic blood pressure to a target pressure. Other aspects are provided herein.
The following commonly assigned U.S. patent applications are related, are all filed on the same date as the present application and are all herein incorporated by reference in their entirety: “Baroreflex Stimulation System to Reduce Hypertension,” U.S. patent application No. 10/746,134, filed on Dec. 24, 2003; “Sensing With Compensation for Neural Stimulator,” U.S. patent application No. 10/746,847, filed on Dec. 24, 2003; “Implantable Baroreflex Stimulator with Integrated Pressure Sensor,” U.S. patent application No. 10/745.921, filed on Dec. 24, 2003; “Automatic Baroreflex Modulation Based on Cardiac Activity,” U.S. patent application No. 10/746.846, filed on Dec. 24, 2003; “Automatic Baroreflex Modulation Responsive to Adverse Event,” U.S. patent application No. 10/745,925, filed on Dec. 24, 2003; “Baroreflex Modulation to Gradually Increase Blood Pressure,” U.S. patent application No. 10/746,845, filed on Dec. 24, 2003; “Baroreflex Stimulation to Treat Acute Myocardial Infarction,” U.S. patent application No. 10/745,920, filed on Dec. 24, 2003; “Baropacing and Cardiac Pacing to Control Output,” U.S. patent application No. 10/746,135, filed on Dec. 24, 2003; “Baroreflex Stimulation Synchronized to Circadian Rhythm,” U.S. patent application No. 10/746.844, filed on Dec. 24, 2003; “A Lead for Stimulating the Baroreflex in the Pulmonary Artery,” U.S. patent application No. 10/746.861, filed on Dec. 24, 2003; and “A Stimulation Lead for Stimulating the Baroreceptors in the Pulmonary Artery,” U.S. patent application No. 10/746,852, filed on Dec. 24, 2003.
This application relates generally to implantable medical devices and, more particularly, to gradually increasing blood pressure with baroreflex modulation.
Various aspects and embodiments of the present subject matter gradually increases the stimulation over a period of weeks or months. This gradual increase discourages the baroreflex from adapting to elevated stimulation, promotes toleration of the therapy, and provides time to reverse remodel stiffening caused by hypertension.
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EventsDateCodeEventDescriptionJun 11, 2004ASAssignmentOwner name: CARDIAC PACEMAKERS, INC., MINNESOTAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:LIBBUS, IMAD;SPINELLI, JULIO C.;REEL/FRAME:014722/0129Effective date: 20040505May 26, 2009CCCertificate of correctionJul 5, 2012FPAYFee paymentYear of fee payment: 4Jul 21, 2016FPAYFee paymentYear of fee payment: 8RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services