Source: http://www.google.com/patents/US20080146903?dq=5,973,252
Timestamp: 2014-07-25 16:20:05
Document Index: 223689318

Matched Legal Cases: ['art 1', 'art 2', 'art 2', 'art 3', 'art 3', 'art 4', 'art 4', 'art 5', 'art 5', 'art 6']

Patent US20080146903 - Display and probe having a removable connections - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign in<nobr>Advanced Patent Search</nobr>PatentsAn apparatus for use with a patient having a vessel carrying blood to ascertain characteristics of the blood. The apparatus includes a display module and a probe having a distal extremity adapted to be inserted into the vessel of the patient and having a proximal extremity coupled to the display module....http://www.google.com/patents/US20080146903?utm_source=gb-gplus-sharePatent US20080146903 - Display and probe having a removable connectionsAdvanced Patent SearchPublication numberUS20080146903 A1Publication typeApplicationApplication numberUS 12/027,898Publication dateJun 19, 2008Filing dateFeb 7, 2008Priority dateSep 9, 2003Also published asCA2538122A1, CN101052343A, CN101052343B, EP1662977A2, EP1662977A4, US7630747, US20050054905, US20080125632, US20080125633, US20080125635, US20080139909, WO2005023097A2, WO2005023097A3Publication number027898, 12027898, US 2008/0146903 A1, US 2008/146903 A1, US 20080146903 A1, US 20080146903A1, US 2008146903 A1, US 2008146903A1, US-A1-20080146903, US-A1-2008146903, US2008/0146903A1, US2008/146903A1, US20080146903 A1, US20080146903A1, US2008146903 A1, US2008146903A1InventorsPaul D. Corl, James D. Mikkelsen, Harry D. Nguyen, Amos Gottlieb, Margaret R. WebberOriginal AssigneeCorl Paul D, Mikkelsen James D, Nguyen Harry D, Amos Gottlieb, Webber Margaret RExport CitationBiBTeX, EndNote, RefManPatent Citations (1), Referenced by (1), Classifications (15), Legal Events (1) External Links: USPTO, USPTO Assignment, EspacenetDisplay and probe having a removable connectionsUS 20080146903 A1Abstract An apparatus for use with a patient having a vessel carrying blood to ascertain characteristics of the blood. The apparatus includes a display module and a probe having a distal extremity adapted to be inserted into the vessel of the patient and having a proximal extremity coupled to the display module. The probe includes a sensor in the distal extremity for providing an electrical signal to the display module when the probe is disposed in the blood. The probe can have an antithrombogenic surface treatment for inhibiting the adhesion of blood components to the probe when disposed in the blood.
1. An apparatus for use with a patient having a vessel carrying blood to ascertain characteristics of the blood comprising a display module and a probe, the probe having proximal and distal extremities, the distal extremity of the probe being adapted to be inserted into the vessel of the patient and having a gas sensor assembly for providing an electrical signal when the probe is disposed in the blood, the display module having a first connector, the proximal extremity of the probe having a second connector for mating with the first connector, the second connector having a cylindrical portion and an electrical contact extending around at least a portion of the cylindrical portion, a conductor extending though the probe for electrically coupling the gas sensor assembly with the electrical contact, the electrical contact being seated flush with the cylindrical portion so as to provide the second connector with a substantially smooth cylindrical surface, the first and second connectors permitting connection and disconnection between the probe and the display module.
2. The apparatus of claim 1 further comprising a band connected to the display module for securing the control and display module to the wrist of the patient.
3. The apparatus of claim 1 further comprising an additional electrical contact extending around at least a portion of the cylindrical portion and spaced apart from the first-named electrical contact. Description
CROSS-REFERENCE TO RELATED APPLICATIONS This application is a divisional of U.S. patent application Ser. No. 10/658,926, filed Sep. 9, 2003, the disclosure of which is hereby incorporated by reference in its entirety.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT Referring to FIG. 1, an apparatus 10 according to the present invention for making intravascular measurement of physiological parameters or characteristics generally includes a display module 12 and one or more probes 18. As described in more detail herein, the display module 12 and probe 18 are particularly adapted for accurate and continuous in vivo measurement and display of intravascular parameters such as partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2), and pH. In addition, cardiac output (CO) can be calculated by combining two measurements of PO2 obtained from a pair of probes, one disposed in an artery and the other in a vein. Alternatively, or in addition to the aforementioned sensors, the probe 18 may include sensors for other useful blood parameters such as potassium, sodium, bilirubin, hemoglobin, glucose, pressure, etc. Additional features of the display module 12 and probe 18 are detailed hereinafter and in copending U.S. patent application Ser. No. 09/956,064 filed Sep. 18, 2001 and now U.S. Pat. No. 6,616,614, the entire content of which is incorporated herein by this reference.
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Chart 1 shows the performance of a representative example of an oxygen sensor probe over a range of dissolved oxygen concentrations from zero to 150 mmHg partial pressure of oxygen. The response is linear over the range of interest, making the calibration to 5% accuracy a simple process. Besides exhibiting accuracy and linearity, the oxygen sensor provides rapid response to changes in the dissolved oxygen concentration. Chart 2 shows the time response of a representative oxygen sensor probe to a sequence of step changes in oxygen partial pressure, demonstrating a settling time of less than 3 minutes to a within 5% of the final value. Chart 2 Oxygen Sensor Response Besides demonstrating accuracy, linearity, and rapid response, the oxygen sensor provides greater than 72 hours of longevity to satisfy the requirements of the ICU/CCU monitoring application. Chart 3 shows the stability of the oxygen sensor output over the course of a 90-hour longevity study. With a constant, room air, partial pressure of oxygen of 150 mmHg, the output of the sensor remains nearly constant for greater than 72 hours except for the expected small variations in output due to temperature fluctuations and noise. Chart 3 Oxygen Sensor Longevity Chart 4 shows the performance of a representative example of a carbon dioxide sensor probe over a range of dissolved carbon dioxide concentrations from 10 to 100 mmHg partial pressure of carbon dioxide. The response shows the classic logarithmic performance expected for this type of pH-responsive sensor, making calibration to 5% accuracy a simple process. Chart 4 Carbon Dioxide Sensor Performance Besides exhibiting accuracy and linearity, the carbon dioxide sensor provides rapid response to changes in the dissolved carbon dioxide concentration. Chart 5 shows the time response of a representative carbon dioxide sensor probe to a sequence of step changes in carbon dioxide partial pressure, demonstrating a settling time of less than three minutes to a within 5% of the final value. Chart 5 Carbon Dioxide Sensor Response Besides demonstrating accuracy, linearity, and rapid response, the carbon dioxide sensor has an inherently long lifetime, since it does not consume the electrodes or the electrolyte solution as oxygen sensor does.
Chart 6 shows the performance of a representative pH sensor output over a range of pH from 4 to 10. This pH sensor is mounted in a multi-sensor probe that also includes oxygen, carbon dioxide, and temperature sensors. The response shows the classic linear voltage response to the logarithmic pH parameter. The standard deviation for repeated measurements at a single pH value is approximately 0.02 pH, demonstrating that calibration to the required 0.05 pH accuracy over the physiological range of pH from 7 to 8 is feasible. The response time of the pH sensor is fast, with a settling time of approximately 10 seconds to a step change in the pH value.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS20080114433 *Jan 16, 2008May 15, 2008Medtronic, Inc.Implantable Medical Lead and System, and Method of Use Thereof* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS7630747Sep 9, 2003Dec 8, 2009Keimar, Inc.Apparatus for ascertaining blood characteristics and probe for use therewithClassifications U.S. Classification600/364International ClassificationA61B5/1459, A61B5/00Cooperative ClassificationA61B5/1473, A61B5/01, A61B2562/227, A61B5/14542, A61B5/6852, A61B5/14546, A61B5/14539European ClassificationA61B5/1473, A61B5/145N, A61B5/68D1H, A61B5/145J, A61B5/145PLegal EventsDateCodeEventDescriptionNov 22, 2010ASAssignmentEffective date: 20101027Owner name: KNOBBE, MARTENS, OLSON & BEAR, LLP, CALIFORNIAFree format text: SECURITY INTEREST;ASSIGNOR:KEIMAR, INC.;REEL/FRAME:025309/0123RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google