Source: https://patents.google.com/patent/EP1430829A1/en
Timestamp: 2020-04-04 03:16:08
Document Index: 728174387

Matched Legal Cases: ['art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'art 4', 'application No. 02405272']

EP1430829A1 - Ophthalmic device and measuring method - Google Patents
Ophthalmic device and measuring method Download PDF
EP1430829A1
EP1430829A1 EP02406102A EP02406102A EP1430829A1 EP 1430829 A1 EP1430829 A1 EP 1430829A1 EP 02406102 A EP02406102 A EP 02406102A EP 02406102 A EP02406102 A EP 02406102A EP 1430829 A1 EP1430829 A1 EP 1430829A1
EP02406102A
EP1430829B1 (en
Dr.Ing. Christian Rathjen
2002-12-16 Application filed by SIS AG Surgical Instrument Systems filed Critical SIS AG Surgical Instrument Systems
2002-12-16 Priority to EP02406102A priority Critical patent/EP1430829B1/en
2004-06-23 Publication of EP1430829A1 publication Critical patent/EP1430829A1/en
2008-04-09 Publication of EP1430829B1 publication Critical patent/EP1430829B1/en
2009-10-21 First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32338235&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1430829(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
An ophthalmological device (1) and an ophthalmological measuring method are proposed, in which a light beam (11), for example a light gap, through a cross-sectional part (4) of an eye (3), in particular through a cross-sectional part (4) of the cornea, by means of a light projector (11) of the eye (3) is projected. A cross-sectional image (30A) of at least a partial area of the cross-sectional part (4) illuminated by the light projector (11) is captured by image capturing means, which are arranged in a Scheimpflug arrangement to form the beam (2). A view image (3A) of the eye (3), which comprises an image of the cross-sectional part (4) illuminated by the first light projector (11), is captured by further image capturing means and stored in association with the captured cross-sectional image (30A). The relative position of the stored cross-sectional image (30A) to the eye (3) is determined on the basis of the associated stored view image (3A) and the stored cross-sectional image (30A) is positioned relative to previously saved cross-sectional images of the eye (3). A continuous examination of the entire eye (3) is made possible, taking into account relative movements of the eye (3) relative to the device (1). <IMAGE>
The present invention relates to an ophthalmic device and an opthalmological measurement method. The invention relates in particular an ophthalmic device and an ophthalmic measuring method, in which a beam of light through a Cross-sectional part of an eye is projected, in particular by a Cross-sectional part of the cornea, in which by means of first image acquisition means, which are arranged in a Scheimpflug arrangement to form a beam Cross-sectional image of at least a partial area of the through the Light projector illuminated part of the cross section from a first position is recorded and stored outside the beam, and in which captured a view image of the eye by means of second image capturing means and stored in association with the captured cross-sectional image.
In the prior art, ophthalmic devices and known ophthalmic measuring methods, in which by means of a Light projector projecting a beam of light through a cross-sectional portion of an eye, in particular through a cross-sectional part of the cornea. The beam is typically projected in the form of a light gap. In the patent US 5404884 a method and an apparatus for described the examination of a patient's corneal tissue. According to US 5404884 describes an essentially flat laser beam with a slit-shaped profile projected through a cross-sectional part of the cornea. By the detection of at least a part of the scattered in the cornea According to US, light, i.e. from at least part of the light gap, is used 5404884 obtained a cross-sectional image of the cornea. From several of them Cross-sectional images of the cornea can be according to US 5404884 Corneal opacities, corneal thickness and corneal topography comprehensive for the entire cornea can be determined. Since the eyes are relative to the Examination device can move, the examination of the entire eye according to US 5404884 lead to inaccuracies because of this Relative movements are not recorded and taken into account. In technical article B. R. Masters et al. , "Transformation of a Set of Slices Rotated on a Common Axis to a Set of Z-Slices: Application to Three-Dimensional Visualization of the In Vivo Human Lens, "Computerized Medical Imaging and Graphics, Vol. 21, No. 3, pages 145 to 151, 1997, it is explicitly pointed out that itself upon extensive examination of the eye based on the reassembly based on several cross-sectional images, due to the difficulty of the mutual alignment of the individual cross-sectional images measurement artifacts can result.
In US 4711541 an opthalmological Device described, via a slit lamp for projecting a Light gap on the lens of an eye. The device according to US 4711541 also includes a photo camera that is related to the plane of the Light gap is arranged according to Scheimpflug conditions to the entire Cross-sectional part of the eye lens, which is illuminated by the light gap, to depict sharply. The device according to US 4711541 has a Stereo microscope to give the user a top view of the eye enable. By means of optical elements of the device, the supervision can Illustration of the photo camera are fed. However, means Polarization filters ensure that not the one on the surface of the Eye lens reflected light gap, but only the one visible in the top view Backlighting of the eye caused by the reflection of the light gap on Background of the eye and the scattering through the lens of the eye results from the Photo camera is fed for imaging. Using a movable mirror the light section in the eye lens and the eye supervision with the Backlight mapped onto the same photograph side by side become. Since the device according to US 4711541 only has one examination Individual images, no coherent examination of the entire eye.
In US 5341180 an ophthalmic Image recording device described, which by means of a slit lamp Projected light gap on one eye. The image recording device comprises one CCD camera (Charged Coupled Device) to the level of the light gap is arranged according to Scheimpflug conditions to the entire Cross-sectional part of the eye that is illuminated by the light gap, sharp map. The device according to US 5341180 comprises a second CCD camera, which gives the user supervision of the eye to be examined granted and to align the device or the eye with the help of light marks projected onto the eye. The device according to US 5341180 has polarization filters to prevent the light gap is visible in the supervision of the second CCD camera. For precise alignments To enable, the patient to be examined must Focus eyes on fixation marks, which is what an examination of the whole eye can be perceived by the patient as troublesome and is also time consuming.
It is an object of the present invention, a new one ophthalmic device and a new ophthalmic measuring method propose which do not have the disadvantages of the prior art and in particular a coherent investigation of the whole Enable eye, in particular the determination of topography and Measured values of structures of the anterior chamber of the eye, for example the Corneal topography and thickness, with relative movements of the eye to Device are taken into account.
According to the present invention, these goals are particularly achieved through the elements of the independent claims. More beneficial Embodiments also go from the dependent claims and the description.
The ophthalmic device comprises a first one Light projector for projecting a beam through a cross-section an eye, in particular through a cross-sectional part of the cornea Eye, first image capturing means for capturing and storing a Cross-sectional image of at least a portion of the through the first Light projector illuminated part of the cross section, from a first position outside the beam, which is arranged in a Scheimpflug arrangement Beams are arranged, and second image capturing means for capturing a view image of the eye and for storing the captured View image assigned to the captured cross-sectional image.
The above objectives are particularly noticeable by the invention achieved in that the second imaging means of this ophthalmic device are set up for detection and Storage of the view image in such a way that the view image is an image of the cross-section part illuminated by the first light projector, and that this ophthalmic device includes processing means for Positioning the saved cross-sectional image relative to the eye on the Basis of the assigned saved view image. The capture and Storage of the cross-sectional image and the associated view image With the illuminated cross-section, the position can be determined the cross-sectional image or the illuminated cross-sectional part captured therein relative to the eye based on the assigned view image, which in turn is a coherent examination of the entire eye with several cross-sectional images, the relative movements of the Eye based on the determined positions of the relevant cross-sectional images can be taken into account. As reference points for the Positioning can use natural features of the eye such as limbus, iris or pupil can be used, which are shown in the view image. To the relative position is automatically determined for each cross-sectional image, the entire eye can be examined contiguously by several cross-sectional images according to their assigned position a three-dimensional image of the eye. It will enables a coherent examination of the entire eye at the relative movements of the eye to the device are taken into account without that the patient to be examined opens his eyes every time he takes a picture Focusing marks must be focused to avoid measurement errors. From several Cross-sectional images that correspond to their specific position can be joined together, for example corneal thickness, Comprehensive corneal topography and / or corneal opacity for the entire Cornea of the eye can be determined. The processing means are preferably set up for positioning several stored Cross-sectional images relative to each other based on each of them associated saved view images.
The processing means are in an embodiment variant set up to determine the thickness of the through the first light projector illuminated cross-sectional part of the eye based on the stored View image. Because the beam of light projected by the first light projector has a finite thickness and can be divergent, the thickness of the illuminated cross-section in the outside of the beam Cross-sectional image larger or larger depending on the thickness of the beam smaller. Determining the thickness of the through the first light projector Illuminated cross section of the eye has the advantage that the influence of the finite thickness of the beam when measuring the thickness of illuminated Cross-sectional parts of the eye, for example when measuring corneal thickness, taken into account and the thickness measurement can be corrected accordingly, which leads to higher measuring accuracy. For determining the thickness of the through the first light projector illuminated cross-section or respectively A bundle of rays turns out to be a top view image, i.e. a view image in which the second image capturing means are arranged so that their optical Axis substantially parallel to the optical axis or the visual axis of the Eye runs or with the optical axis or the visual axis of the eye coincides as particularly advantageous because it is particularly precise and simple, if the optical axis of the second image capturing means corresponds to that of the Cross-sectional beam coincides.
The preferred arrangement of the second imaging means and the first light projector, in which the optical axis of the second Image acquisition means with the one running through the cross-sectional part Beam bundle coincides, advantageously also enables one particularly simple and precise position determination of the depicted illuminated cross-section, especially when the eye through the second Image acquisition means is recorded as a top view image.
In a preferred embodiment, the first and the second imaging means arranged so that their optical axes in lie on a common level. With this arrangement, the through first image acquisition means captured cross-sectional images and the by second image acquisition means captured associated view images geometrically easier to relate to each other than this alternative arrangements is possible, which is the relative positioning of several Cross-sectional images with each other and the assembly of these Cross-sectional images simplified.
Preferably comprise the first and the second Image acquisition means a common image converter and the first Image acquisition means comprise beam-deflecting optical elements, the beam-deflecting optical elements are arranged so that light rays to generate the cross-sectional image for the common image converter be redirected. In an alternative embodiment variant, the first and second image acquisition means a common image converter and the second image acquisition means comprise beam-deflecting optical ones Elements, the beam-deflecting optical elements arranged in this way are that light rays for generating the view image for common Image converter are redirected. Both of these variants have the The advantage that they have only one image converter and thus less expensive and can be made more compact than an alternative version with two separate image converters. The first preferred preferred of these two Design variants also has the advantage that the first Image acquisition means in a simple and compact way with others beam-deflecting optical elements can be provided so that Light beams to create multiple cross-sectional images from different ones Positions can be redirected to the common image converter.
The first image acquisition means are preferably set up for Acquisition and storage of a second cross-sectional image of the sub-area of the cross-sectional part illuminated by the first light projector from one second position outside the beam, simultaneously with the Acquisition of the first cross-sectional image, the first position and the second position on different sides of one lying in the beam Lay level and the illuminated cross section, for example, under one Capture equally large viewing angles. The advantage of images of the to capture the illuminated cross-section from several positions in that several measured values are determined and averaged from them more accurate measurement results can be determined. When averaging for example, there are deviations when determining a first one Distance between eye structures in the first cross-sectional image and one second distance between eye structures in the second cross-sectional image each other. If consequently the ophthalmic device is applied in this way is that the beam of rays is substantially perpendicular to that of the Light projector facing (corneal) surface of the eye is projected, there are slight tilting of the beam with respect to the normal to the surface of the cornea facing the light projector for example, not to determine the thickness of the cornea. Even if the device is applied so that the beam of rays is essentially projected along the optical axis of the eye, minor effects Tilting and eccentricities of the beam, that is Shifts from the vertex of the eye, not to the determination of the Corneal thickness. The same applies to small deviations from the Observation angle from the first position from the observation angle to the second position. The advantage of having two cross-sectional images to capture different positions at the same observation angles, is that there are small inaccuracies in the application, the Adjustment and / or calibration of the ophthalmic device without large deviations affect the measurement results. Will the ophthalmic device applied, for example, in meridian sections, then a calibration in the meridian section is sufficient to also with slight eccentricities and to be able to measure tilting precisely. The opthalmological device thus enables easier application and Execution while maintaining the accuracy of the measurement results.
In the embodiment variant in which the first image capturing means comprise an image converter and further beam-deflecting optical elements, are preferably the first of the beam deflecting optical elements arranged first position that light beams for generating the first Cross-sectional image are redirected to the image converter, and the second beam-deflecting optical elements are in the second position arranged that light beams for generating the second cross-sectional image be redirected to the image converter. This results in a particularly compact and inexpensive execution.
In one embodiment, the opthalmological includes Device one or more additional second light projectors Projection of light marks on the eye and the second image capturing means are with the first light projector and with the second light projectors synchronizes that when capturing and storing the view image of the Eye, the image of the cross-sectional part illuminated by the first light projector and an image of those projected by the second light projectors Light marks are also recorded and saved. The projected and co-registered light marks serve as artificial reference marks which are used for Determination of the relative position of the ophthalmic device for Eye and thus for determining the position of the cross-sectional image, respectively of the illuminated cross-section can be used.
In one embodiment, the opthalmological includes Device a screen body with a visible pattern, which Umbrella body is arranged so that the visible pattern during application the device on a side of the screen body facing the eye lies and that the beam of rays is unhindered by the cross-sectional part of the Eye projectable and that the cross-sectional image and the view image unhindered by the first or second image capturing means are. Since the visible pattern, for example a placido pattern, is shown by the Is reflected, it can be captured with the view image and as Artificial reference pattern to determine the relative position of the ophthalmic device for the eye and thus for position determination the cross-sectional image or the illuminated cross-sectional part be used.
In one embodiment, the opthalmological includes Device driving means to the first light projector and the first and the second image capturing means essentially a normal to that first light projector facing the surface of the eye to rotate or To move essentially perpendicular to this normal. Through this An automated, coherent investigation of the entire eye based on several cross-sectional images.
The first light projector is preferably designed in such a way that it does Beams of rays projected in the form of a light gap. Although others too Shapes of the beam can be used, for example point-like, a bundle of rays in the form of a light gap is particularly suitable for continuous examination of the entire eye based on several light sections of the eye.
The second image acquisition means are preferably so arranged that its optical axis with the optical axis of the eye coincides or is substantially parallel to the optical axis of the Eye runs. As a result, the eye can be captured as a top view image both for determining the position of the illuminated cross-section part also advantageous for determining the thickness of the illuminated cross-section is, as previously explained. In combination with the preferred Arrangement of the second image capturing means and the first light projector, in which the optical axis of the second image acquisition means with that through the Cross-sectional part of the bundle of rays coincides, there is a Arrangement in which the first light projector projects the beam of rays so that the bundle of rays coincides with the optical axis of the eye or that the beam is parallel to the optical axis of the eye runs.
An embodiment of the present invention is described below using an example. The example of the execution is illustrated by the following enclosed figures:
FIG. 1a shows a block diagram which schematically illustrates an ophthalmological device with a light projector, an image capturing device for capturing a cross-sectional image of an eye, an image capturing device for capturing a view image of the eye and an additional light source.
FIG. 1b shows a cross-sectional image of an illuminated cross-sectional part of an eye (cornea).
Figure 1c shows a view image of an eye with an illuminated cross-section.
FIG. 2a shows a block diagram which schematically illustrates an ophthalmological device with a light projector, an image capturing device for capturing a cross-sectional image of an eye, an image capturing device for capturing a view image of the eye and a perforated screen body.
FIG. 2b shows a view of the side of a screen body facing the eye with openings and a visible pattern.
FIG. 3 shows a sectional view of an illuminated cross-sectional part of an eye, in which the beam path of the incident and reflected beam is illustrated schematically.
FIG. 4 shows a block diagram which schematically illustrates a side view of an ophthalmological device with a light projector and an image capturing device aligned along the optical axis of the eye for capturing a view image of an eye.
FIG. 5 shows a block diagram which schematically illustrates an ophthalmological device with a light projector and an image capturing device for capturing a view image of an eye, in which the optical axis of the image capturing device coincides with the beam of rays running through the cross-sectional part.
FIG. 6 shows a block diagram which schematically illustrates an ophthalmological device with a light projector and image capturing means for capturing a cross-sectional image and a view image of an eye, in which light beams for generating the view image and light rays for generating the cross-sectional image are fed to a common image converter by means of beam-deflecting optical means.
FIG. 7 shows a block diagram which schematically illustrates a further embodiment of an ophthalmological device with a light projector and image capturing means for capturing a cross-sectional image and a view image of an eye, in which light rays for generating the view image and light rays for generating the cross-sectional image by means of beam-deflecting optical means, a common image converter be fed.
FIG. 8 shows a combined image with a cross-sectional image of an illuminated cross-sectional part of an eye and a view image of the eye with the illuminated cross-sectional part.
FIG. 9 shows a block diagram which schematically illustrates an ophthalmological device with a light projector and image capturing means for capturing two cross-sectional images and a view image of an eye, in which light rays for generating the view image and light rays for generating a first cross-sectional image from a first position and light rays for generating a second cross-sectional image from a second position can be fed to a common image converter by means of beam-deflecting optical means.
FIG. 10 shows a combined image with a first cross-sectional image of an illuminated cross-sectional part of an eye from a first position, a view image of the eye with the illuminated cross-sectional part and a second cross-sectional image of the illuminated cross-sectional part from a second position.
In Figures 1a, 2a, 4, 5, 6, 7 and 9, this denotes Reference numeral 1 an ophthalmic device, wherein in the the following description with reference to these figures Embodiments of the ophthalmic device 1 are explained. Otherwise, identical components are shown in the figures designated by the same reference numerals.
The shown in Figures 1 a, 2a, 4, 5, 6, 7 and 9 Embodiments of the ophthalmic device 1 include one Light projector 11 for projecting a beam 2 through a Cross-sectional part of an eye 3, in particular through a cross-sectional part of the Cornea 30 of the eye 3. The beam 2 is preferably in shape of a light gap projected. The light projector 11 includes, for example Slit lamp or a laser, the light of which by beam shaping optics too a fan is formed.
The shown in Figures 1 a, 2a, 4, 5, 6, 7 and 9 Embodiments of the ophthalmic device 1 include Image acquisition means for acquiring and storing a cross-sectional image 30A of at least a portion of the area through the light projector 11 illuminated cross-section 4, which in Scheimpflug arrangement for Beams 2 are arranged.
Those shown in Figures 1a, 2a, 4, 5, 6, 7 and 9 Embodiments of the ophthalmic device 1 also include further image capturing means for capturing a view image 3A of the eye 3, which comprises an image of the illuminated cross-sectional part 4A, and Storage of the captured view image 3A and the one contained therein Image of the illuminated cross-sectional part 4A assigned to the captured Cross-sectional image 30A.
As shown in Figures 1a, 2a, 4, 5, 6, 7 and 9, include the image capturing means depending on the embodiment of the ophthalmic Device 1 Image capture devices 12A, 12B, for example CCD cameras (Charged Coupled Device) or CMOS cameras (Complementary Metal oxide silicone), image converter 120, for example CCD chips or CMOS chips, beam-deflecting optical elements 121 A, 121 B, 121 E, for example Mirrors, beam-deflecting optical elements 121 C, 121 D, for example beam-splitting optical elements such as semi-transparent mirrors, and / or imaging optical elements 122A, 122B, 122C, for example lenses.
For the visualization of natural eye features such as limbus 33, iris 34 or pupil 35, and / or for the projection of artificial light marks 36 include those shown in Figures 1a, 2a, 4, 5, 6, 7 and 9 Embodiments of the ophthalmic device 1 one or more additional light sources 16. In particular to make natural ones visible Eye features can be, for example, one or more infrared light-emitting diodes be used. The natural and / or artificial reference features are included in the view image 3A of the eye 3.
Those shown in Figures 1a, 2a, 4, 5, 6, 7 and 9 Embodiments of the ophthalmic device 1 include Processing means 13 with functional modules for processing captured view images 3A and cross-sectional images 30A. The Processing means 13 comprise at least one processor, data and Program memory. The functional modules are preferably as programmed software modules executed in the program memory are stored and executed on the processor. The expert will understand that the functional modules are also partial or complete hardware can be executed.
The functional modules of the processing means 13 comprise a programmed positioning module, which the position of a stored cross-sectional image 30A relative to the eye 3 determined. The relative positioning is done based on the view images 3A that represent the Cross-sectional images 30A are associated with each. The position determination A cross-sectional image 30A takes place by determining the position of the eye 3 relative to the ophthalmic device 1. The relative position of the ophthalmic device 1 to the eye 3 on the basis of the image the illuminated cross-sectional part 4A, the natural features of the eye 3 and / or the mapped artificial reference features, for example the shown light marks 36 determined. The position of a cross-sectional image 30A or the associated image of the illuminated cross-sectional part 4A can be defined with reference to the natural features of the eye 3 which are contained in the relevant view image 3A.
The functional modules of the processing means 13 comprise also a programmed composition module, which recorded several and stored cross-sectional images 30A positioned relative to each other. The Composition module adds knowledge of the geometric arrangement of the ophthalmic device 1 the detected and stored Cross-sectional images 30A according to their relative position to the eye 3 to each other to form a three-dimensional image of the eye 3 together, in particular into a three-dimensional image of Anterior chamber structures of the eye 3, in particular the cornea 30.
The functional and sequence control of the ophthalmic Device 1 can by the processing means 13 and / or by others Electronic control modules, not shown, take place.
The electrical supply of the ophthalmic device 1 done by an internal or by a cable connected external energy source.
Those shown in Figures 1a, 2a, 4, 5, 6, 7 and 9 Embodiments of the ophthalmic device 1 include one Display 14, on which certain measured values and / or application aids are displayed.
Those shown in Figures 1a, 2a, 4, 5, 6, 7 and 9 Embodiments of the ophthalmic device 1 include Drive means 15 for rotating the light projector 11 and the Image acquisition means, essentially a normal to that Light projector 11 facing surface of the eye 3 or for moving of these components essentially perpendicular to this normal. As in 9 is shown schematically, the light projector 11 and the Image acquisition means 120, 121A, 121B, 121C, 122A, 122B, 122C to this Purpose attached to a movable support device 10, which by the drive means 15 is driven. The additional light source (s) 16 can be attached to the carrier device 10 and moved with it or they can be attached to the ophthalmic device 1, that they are not coupled to the drive means 15. The drive means 15 preferably comprise a rotation driver, for example a Electric motor, which the carrier device 10 about the optical axis Z of the eye rotates. By rotating the light projector 11 and the image capturing means 120, 121A, 121B, 121C, 122A, 122B, 122C about the optical axis Z will the entire eye, in particular the entire cornea 30. In this Configuration can be the least due to the high symmetry Achieve measurement uncertainties.
As shown in FIG. 1a, the Image capture device 12A for capturing and storing Cross-sectional images 30A imaging optical elements 122A and one Image converter 120, which is projected in a Scheimpflug arrangement Beams 2 are arranged. In Figure 1 b is a through Image capture device 12A captures cross-sectional image 30A of the Illuminated cross section 4 of the eye 3 shown. Other structures of the eye 3, such as the iris or lens, are shown in FIG. 1b for the sake of simplicity not shown. In cross-sectional image 30A are in particular a Cross-sectional image of the anterior corneal surface 31 A and a Cross-sectional image of the posterior corneal surface 32A visible. In the Embodiment according to Figure 1a is the optical axis of the separate image capturing device 12B for capturing the view image 3A of the eye 3 outside the beam 2. The in the figure 1c shown view image 3A of the eye 3, however, corresponds to one View image taken by an image capture device 12B as a top view is captured with the image capturing device 12B arranged so that its optical axis essentially parallel to the optical axis Z of the Eye 3 or the visual axis of the eye 3 runs or with the optical axis Z or the visual axis of the eye 3 coincides, for example in the Figures 4 and 5 is shown. In the view image 3A are in particular a Image of the illuminated cross-sectional part 4A with the finite thickness d that projected light marks 36 as well as limbus 33, iris 34 and pupil 35 of the eye 3 visible. Light marks are, for example, highlights of light emitting diodes or projected points. Projection locations are, for example, the sclera 37 or the Cornea 30. The acquired cross-sectional image 30A and the acquired View image 3A are fed to the processing means 13 and there in the Data storage is stored assigned to each other. The light projector 11 and the Image acquisition means 12A, 12B are separated into further ones by the drive means 15 Recording positions moved and there are further cross-sectional images 30A and view images 3A captured and stored in association with each other.
In Figure 2a is an embodiment of the ophthalmic Device 1 shown, which has a perforated screen body 17th includes. The openings 171, 172, 173 of the shield body 17 are each arranged so that the beam paths to the image capture means 12A, 12B and to the light projector 11 the screen body 17 unhindered can happen. On the side of the screen body facing the eye 3 17 is a visible pattern 17 ', a so-called placido pattern, attached, for example, with circular rings 174 which through the surface of the Eye 3 is mirrored, as known for example from keratometers. On light sources can also face the screen body 17 facing the eye 3 be attached, for example light projectors 16 for projecting Light marks 36. A view of the side of the eye facing 3 Shield body 17 with openings 171, 172, 173 and the visible Pattern 17 'is shown in Figure 2b. The reflection of the visible Pattern 17 'on the eye surface is created by the image capture device 12B is shown in the view image 3A and can be used in the positioning of the Cross-sectional images 30A as an artificial reference pattern for the determination the relative position of the ophthalmic device 1 to the eye 3 be used. The shield body 17 is preferably so with the Drive means 15 connected to the light projector 11 and the Image acquisition means is moved. In an alternative execution can the shield body 17 also on the ophthalmological device 1 attached that it is not coupled to the drive means 15, the openings 171, 172, 173 are adapted accordingly. On at this point it should be mentioned that the shield body 17 also in this way can be arranged that the image capturing means 12A, 12B and / or the Light projector 11 to lie between the screen body 17 and the eye 3 come, the image capturing means 12A, 12B and / or Light projector 11, for example on the side of the eye facing 3 Umbrella body 17 attached.
Figure 3 shows a sectional view of an illuminated Cross-sectional part 4 of the eye 3, in particular the cornea 30. In FIG. 3 reference numeral 31 denotes the anterior corneal surface and the Reference numeral 32 the posterior corneal surface. The cornea 30 is through the beam 2 is illuminated in the cross-sectional part 4. As in FIG. 3 is shown, the beam 2 has a finite thickness d. The reflected light rays 21, 22 leave the thickness D of the illuminated Cross-sectional part 4 in a cross-sectional image 30A due to the finite Thickness d of the beam appears thicker than it actually is. Since the Geometric arrangement of light projector 11 and image capturing means is known, the influence of the finite thickness d of the beam 2 on the cross-sectional image 30A or on measured values which result from the Cross-sectional image 30A can be determined knowing the value of the finite Thickness d can be corrected. The finite thickness d of the beam 2 can can be determined particularly precisely if the view image 3A by the Image acquisition means is recorded in the supervision.
In the embodiment of the ophthalmic device 1 4, the image capturing device 12B is arranged such that a view image 3A can be captured, which is a top view of the eye 3 equivalent. The optical axis of the image capturing device 12B can be but for the application along the optical axis Z of the eye 3 align. As the side view in FIG. 4 shows, the beam of rays 2, which is shown in this view as a light plane (or light fan), in this embodiment laterally from outside the optical axis of the Image capture device 12B projected onto the eye 3.
5 shows a further embodiment of the shown ophthalmic device 1, which a view image 3A with a supervision of the eye 3 enables. In the embodiment according to FIG. 5 fall the beam 2 of the light projector 11 by the Cross-sectional part 4 runs, and the optical axis of the Image capturing device 12B for capturing the view image 3A together. This is achieved, for example, in that the Image capturing device 12B and the light projector 11 thus arranged that their optical axes lie in a common plane, where the beam 2 of the light projector 11 by means of the beam deflecting optical element 121 C, on the optical axis of the Image capture device 12B is steered. By collapsing the through the cross-section 4 extending beam 2 and the optical Axis of the image capturing device 12B becomes a particularly accurate and simple determination of the finite thickness d of the beam 2 and the Position of the cross-sectional images 30A from the view image 3A enables.
6 shows a further embodiment of the shown ophthalmic device 1, which a view image 3A with a supervision of the eye 3 enables and in which the by Cross-sectional part 4 extending beams 2 and the optical axis of the Image capturing means for capturing the view image 3A coincide. The Embodiment according to Figure 6, however, has the advantage over that of Figure 5 that both the cross-sectional image 30A and the view image 3A by means of a single common image converter 120 be recorded. The embodiment according to FIG. 6 results as Further development of the embodiment according to Figure 1a, the Light rays for generating the view image 3A from the top view by means of the beam-deflecting optical element 121D which is in the optical axis of the Light projector 11 is arranged by means of the imaging optical elements 122C and by means of the beam deflecting optical element 121 E Image converter 120 is supplied.
7 shows a further embodiment of the shown ophthalmic device 1, which a view image 3A with a supervision of the eye 3 enables and in which the by Cross-sectional part 4 extending beams 2 and the optical axis of the Image capturing means for capturing the view image 3A coincide. The Embodiment according to FIG. 7, however, has the advantage over that of Figure 5 that both the cross-sectional image 30A and the view image 3A by means of a single common image converter 120 be recorded. Compared to the embodiment according to FIG. 6, it points also the advantage that it is easier and more compact to carry out. The The embodiment according to FIG. 7 results from a further development of the Embodiment according to Figure 5, wherein the light rays for generating the Cross-sectional image 30A by means of the imaging optical elements 122A, the with the image converter 120 in a Scheimpflug arrangement for through the Cross-sectional part 4 extending beam 2 is arranged, and by means of of the beam deflecting optical element 121A to the image converter 120 is fed. The image capturing device 12B shown in FIG. 5 corresponds to the combination of the image converter 120 and the imaging optical elements 122C of FIG. 7.
FIG. 8 shows the combined cross-sectional image 30A and View image 3A shown by imager 120 of FIG Embodiments according to Figures 6 and 7 is detected. The combined Image can be generated as shown in Figure 8 by the Cross-sectional image 30A and view image 3A separated side by side be recorded. The cross-sectional image 30A and the view image 3A can with the help of color filters, for example from color cameras are known, and several light sources with different colors, however also partially or completely superimposed. An image separation is then carried out by the processing means 13 on the basis of the colors. It is also possible to use optical or electrical closures (so-called Shutters) and the cross-sectional image 30A and the view image 3A quickly to be captured as separate images in succession, so that Relative movements between eye 3 and ophthalmic device 1 have no noticeable influence. When using cameras resp. image converters with fields and pulsed light sources can do that Cross-sectional image 30A and the view image 3A synchronized in succession are captured as two fields.
FIG. 9 shows a further embodiment of the ophthalmological device 1, which enables a view image 3A with a view of the eye 3 and in which the beam 2 running through the cross-sectional part 4 and the optical axis of the image acquisition means for acquiring the view image 3A coincide. The embodiment according to FIG. 9 results from a further development of the embodiment according to FIG. 7, the ophthalmological device 1 being provided with further imaging optical elements 122B and a further beam-deflecting optical element 121B in order to additionally acquire a second cross-sectional image 30B. The imaging optical elements 122A and the beam-deflecting optical element 121A guide the light beams for acquiring the cross-sectional image 30A from a first position at the observation angle α A for acquisition to the image converter 120. The additional imaging optical elements 122B and the additional beam-deflecting optical element 121B guide them Light beams for acquiring the cross-sectional image 30B from a second position at the observation angle α B for acquisition also at the image converter 120. The two positions are preferably on different sides of the beam 2 and the amounts of the observation angles α A and α B are preferably of the same size. Compared to the embodiment according to FIG. 7, the embodiment according to FIG. 9 has the advantage that measurement results which are determined from measured values on the cross-sectional image 30A in the ophthalmic device 1 according to FIG. 9 from two measured values of two cross-sectional images 30A and 30B, the different positions were recorded, can be determined more precisely by averaging. For example, the corneal thickness D can be determined more precisely by averaging from the measured values D A and D B , as described in the European patent application No. 02405272, which was unpublished at the time of filing.
FIG. 10 shows the combined cross-sectional image 30A, View image 3A and cross-sectional image 30B shown by the Image converter 120 of the embodiments according to FIG. 9 is detected. The Combined image can be generated as shown in Figure 10 by the cross-sectional image 30A, the view image 3A and the cross-sectional image 30B can be recorded separately from one another. The combined image can however, they can also be recorded and presented differently, such as in connection with Figure 8 has already been mentioned. In addition, the expert can do other things Make picture arrangements and, for example, the two Cross-sectional images 30A, 30B directly side by side over the view image 3A represent.
The functional modules of the processing means 13 also include programmed evaluation modules, for example measurement modules, which determine eye structures in the captured and stored cross-sectional images 30A, 30B, in particular images of the cornea with the front corneal surface 31A, 31B and the rear corneal surface 32A, 32B, and based thereon Determine distances and thicknesses, in particular the measured values D A and D B of the distances between the front corneal surface 31A, 31B and the rear corneal surface 32A, 32B for determining the corneal thickness D.
Finally, it should be noted that the opthalmological Device 1 is preferably designed as a compact measurement sample, wherein additional processing equipment for comprehensive coverage of the whole Eye 3 in an external processing unit, for example in one Personal computer, can be executed, the data exchange via a contact-based or contactless communication link is established. Certain measurement results, for example the local corneal thickness D or - topography, can be on the display 14 or on a display of the external Processing unit are displayed.
An ophthalmic device (1) comprising:
a first light projector (11) for projecting a beam (2) through a cross-sectional part (4) of an eye (3), in particular through a cross-sectional part (4) of the cornea of the eye (3),
first image capturing means for capturing and storing a cross-sectional image (30A) of at least a partial area of the cross-sectional part (4) illuminated by the first light projector (11), from a first position outside the beam (2), which are arranged in a Scheimpflug arrangement to the beam (2) , and
second image capturing means for capturing a view image (3A) of the eye (3) and for storing the captured view image (3A) associated with the captured cross-sectional image (30A),
that the second image acquisition means are set up to acquire and store the view image (3A) such that the view image (3A) comprises an image (4A) of the cross-sectional part (4) illuminated by the first light projector (11), and
that the device (1) comprises processing means (13) for positioning the stored cross-sectional image (30A) relative to the eye on the basis of the associated stored view image (3A).
Device (1) according to claim 1, characterized in that the processing means (13) are set up to position the stored cross-sectional image (30A) on the basis of the associated stored view image (3A) relative to previously stored cross-sectional images of the eye (3).
Device (1) according to one of claims 1 or 2, characterized in that the processing means (13) are set up to determine the thickness (d) of the cross-sectional part (4) of the eye (3) illuminated by the first light projector (11) on the Base of the saved view image (3A).
Device (1) according to one of claims 1 to 3, characterized in that the second image capturing means and the first light projector (11) are arranged such that the optical axis of the second image capturing means with the beam (2) extending through the cross-sectional part (4) coincides.
Device (1) according to one of claims 1 to 4, characterized in that the first and the second image capturing means are each arranged so that their optical axes lie in a common plane.
Device (1) according to one of claims 1 to 5, characterized in that the first and the second image acquisition means comprise a common image converter (120) and that the first image acquisition means comprise beam-deflecting optical elements (121A), the beam-deflecting optical elements (121A ) are arranged in such a way that light beams for generating the cross-sectional image (30A) are deflected to the common image converter (120).
Device (1) according to one of claims 1 to 5, characterized in that the first and second image acquisition means comprise a common image converter (120), and that the second image acquisition means comprise beam-deflecting optical elements (121E), the beam-deflecting optical elements (121 E ) are arranged such that light beams for generating the view image (3A) are deflected to the common image converter (120).
Device (1) according to one of claims 1 to 7, characterized in that the first image capturing means are set up for capturing and storing a second cross-sectional image (30B) of the partial area of the cross-sectional portion (4) illuminated by the first light projector (11) from a second position outside the beam (2), simultaneously with the acquisition of the first cross-sectional image (30A), the first position and the second position being on different sides of a plane lying in the beam (2).
Device (1) according to claim 8, characterized in that the first image capturing means comprise an image converter (120) and that the first image capturing means comprise beam-deflecting optical elements (121A, 121B), the first of the beam-deflecting optical elements (121A) thus in the first Position are arranged that light beams for generating the first cross-sectional image (30A) are deflected to the image converter (120) and wherein second of the beam-deflecting optical elements (121B) are arranged at the second position such that light beams for generating the second cross-sectional image (30B) for Image converter (120) can be deflected.
Device (1) according to any one of claims 1 to 9, characterized in that it comprises one or more additional second light projectors (16) for projecting light marks (36) onto the eye (3), and in that the second image capturing means thus with the first Light projector (11) and synchronized with the second light projectors (16), that during the acquisition and storage of the view image (3A) of the eye (3), the image (4A) of the cross-sectional part (4) illuminated by the first light projector (11) and an image of the light marks (36) projected by the second light projectors (16) are also recorded and also stored.
Device (1) according to one of claims 1 to 10, characterized in that it comprises an umbrella body (17) with a visible pattern (17 '), which umbrella body (17) is arranged such that the visible pattern (17') the application of the device (1) lies on a side of the screen body (17) facing the eye (3), and the screen body (17) is arranged in such a way that the beam (2) is unhindered by the cross-sectional part (4) of the eye ( 3) is projectable and that the cross-sectional image (30A) and the view image (3A) can be captured unhindered by the first and second image capturing means, respectively.
Device (1) according to one of claims 1 to 11, characterized in that it comprises drive means (15) to the first light projector (11) and the first and the second image acquisition means substantially by a normal to that of the first light projector (11) facing surface of the eye (3) to rotate or to move substantially perpendicular to this normal.
Device (1) according to one of claims 1 to 12, characterized in that the first light projector (11) is designed such that it projects the beam (2) in the form of a light gap.
Ophthalmic measurement method, comprising:
Projection of a beam (2) through a cross-sectional part (4) of an eye (3), in particular through a cross-sectional part (4) of the cornea of the eye (3), by means of a first light projector (11),
Acquisition and storage of a cross-sectional image (30A) of at least a partial area of the cross-sectional part (4) illuminated by the first light projector (11), from a first position outside the beam (2), by means of first image capturing means arranged in a Scheimpflug arrangement to the beam (2) be, and
Acquisition of a view image (3A) of the eye (3) and storage of the acquired view image (3A) associated with the acquired cross-sectional image (30A) by means of second image acquisition means,
Acquisition and storage of the view image (3A) such that the view image (3A) comprises an image (4A) of the cross-sectional part (4) illuminated by the first light projector (11), and
Determining the position of the stored cross-sectional image (30A) relative to the eye (3) on the basis of the associated stored view image (3A).
Method according to claim 14, characterized in that the stored cross-sectional image (30A) is positioned on the basis of the associated stored view image (3A) relative to previously stored cross-sectional images of the eye (3).
Method according to one of claims 14 or 15, characterized in that the thickness (d) of the cross-sectional part (4) of the eye (3) illuminated by the first light projector (11) is determined on the basis of the stored view image (3A).
Method according to one of claims 14 to 16, characterized in that the second image acquisition means and the first light projector (11) are arranged such that the optical axis of the second image acquisition means coincides with the beam (2) extending through the cross-sectional part (4).
Method according to one of claims 14 to 17, characterized in that the first image acquisition means and the second image acquisition means are arranged such that their optical axes lie in a common plane.
Method according to one of claims 14 to 18, characterized in that the first image capturing means are provided with beam-deflecting optical elements (121A), the beam-deflecting optical elements (121A) being arranged such that light beams for producing the cross-sectional image (30A) are combined with one the second image capturing means shared image converter (120) are deflected.
Method according to one of claims 14 to 18, characterized in that the second image capturing means are provided with beam-deflecting optical elements (121E), the beam-deflecting optical elements (121E) being arranged in such a way that light beams for generating the view image (3A) are combined with one the first image capturing means commonly used image converter (120).
Method according to one of claims 14 to 20, characterized in that simultaneously with the detection of the first cross-sectional image (30A), a second cross-sectional image (30B) of the partial area of the cross-sectional part (4) illuminated by the first light projector (11) by means of the first image capturing means second position outside the beam (2) is recorded and stored, the first position and the second position being determined on different sides of a plane lying in the beam (2).
Method according to claim 21, characterized in that first beam-deflecting optical elements (121 A) of the first image capturing means are arranged at the first position such that they deflect light beams for generating the first cross-sectional image (30A) to an image converter (120) of the first image capturing means, and in that second beam deflecting optical elements (121B) of the first image capturing means are arranged at the second position such that they deflect light beams for generating the second cross-sectional image (30B) to the image converter (120) of the first image capturing means.
Method according to one of Claims 14 to 22, characterized in that light marks (36) are projected onto the eye (3) by means of one or more additional second light projectors (16), and in that the second image capturing means are thus carried out with the first light projector (11) and can be synchronized with the second light projectors (16) in that when the view image (3A) of the eye (3) is captured and stored, the image (4A) of the cross-sectional part (4) illuminated by the first light projector (11) and an image of the part the second light projectors (16) projected light marks (36) are also recorded and also stored.
Method according to one of claims 14 to 23, characterized in that a screen body (17) provided with a visible pattern (17 ') is arranged in such a way that the visible pattern (17') faces the eye (3) and that the beam of rays (2) is freely projected through the cross-sectional part (4) of the eye (3) and that the cross-sectional image (30A) and the view image (3A) are captured unhindered by the first and second image capturing means, respectively.
Method according to one of claims 14 to 24, characterized in that the first light projector (11) and the first and the second image capturing means are rotated substantially around a normal to the surface of the eye (3) facing the first light projector (11) or in To be moved essentially perpendicular to this normal.
Method according to one of claims 14 to 25, characterized in that the first light projector (11) projects the beam (2) in the form of a light gap.
Method according to one of claims 14 to 26, characterized in that the second image capturing means are arranged so that their optical axis coincides with the optical axis (Z) of the eye (3) or substantially parallel to the optical axis (Z) of the eye (3) runs,
Method according to one of claims 14 to 26, characterized in that the second image capturing means are arranged so that their optical axis coincides with the visual axis of the eye (3) or is substantially parallel to the visual axis of the eye (3).
EP02406102A 2002-12-16 2002-12-16 Ophthalmic device and measuring method Active EP1430829B1 (en)
EP02406102A EP1430829B1 (en) 2002-12-16 2002-12-16 Ophthalmic device and measuring method
DE2002512076 DE50212076D1 (en) 2002-12-16 2002-12-16 Opthalmological device and opthalmological measuring method
US10/730,923 US7264355B2 (en) 2002-12-16 2003-12-10 Ophthalmologic device and ophthalmologic measuring method
JP2003415271A JP4553578B2 (en) 2002-12-16 2003-12-12 Ophthalmic apparatus and ophthalmic measurement method
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US8567949B2 (en) 2010-08-05 2013-10-29 Costruzioni Strumenti Oftalmici C.S.O. S.R.L. Ophthalmic device and method
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