Source: http://www.google.com/patents/US5186896?dq=6,548,982
Timestamp: 2014-03-17 18:29:09
Document Index: 176377087

Matched Legal Cases: ['art 16', 'art 15', 'art 15', 'art 16', 'art 16', 'art 16', 'art 16', 'art 16', 'art 15']

Patent US5186896 - Cuvette rotor - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsThe invention relates to a cuvette rotor having at least one radially extending cuvette with a first chamber, a second chamber and a third chamber, the first chamber being located at a central location on the rotor, the third chamber being located at a peripheral location on the rotor, and the second...http://www.google.com/patents/US5186896?utm_source=gb-gplus-sharePatent US5186896 - Cuvette rotorAdvanced Patent SearchPublication numberUS5186896 APublication typeGrantApplication numberUS 07/530,310Publication dateFeb 16, 1993Filing dateMay 30, 1990Priority dateJun 1, 1989Fee statusPaidAlso published asCA2017988A1, CA2017988C, DE3917866A1, DE59006344D1, EP0405162A2, EP0405162A3, EP0405162B1Publication number07530310, 530310, US 5186896 A, US 5186896A, US-A-5186896, US5186896 A, US5186896AInventorsBernhard Bouchee, Karl FickenscherOriginal AssigneeBehringwerke AktiengesellschaftExport CitationBiBTeX, EndNote, RefManPatent Citations (7), Referenced by (12), Classifications (10), Legal Events (9) External Links: USPTO, USPTO Assignment, EspacenetCuvette rotorUS 5186896 AAbstract The invention relates to a cuvette rotor having at least one radially extending cuvette with a first chamber, a second chamber and a third chamber, the first chamber being located at a central location on the rotor, the third chamber being located at a peripheral location on the rotor, and the second chamber being located between the first and third chambers. The cuvette is defined by a top wall, a bottom wall, and side walls. A first barrier defines a boundary between the first and second chambers, and a second barrier defines a boundary between the second and third chambers. First, second and third ports are disposed in the top wall of the cuvette above the first, second and third chambers, respectively, and a first deflector is disposed between the first and second ports and connected to the top wall of the cuvette. Similarly, a second deflector is disposed between the second and third ports and is connected to the top wall of the cuvette. Finally, at least one vessel having top and bottom walls is arranged on the rotor adjacent the cuvette, the vessel being separated from the cuvette by a side wall, and the top wall of the vessel including a fourth port.
What is claimed is: 1. A cuvette rotor, comprising:at least one radially extending cuvette for centrifuging samples about a central axis, the cuvette having first, second and third chambers respectively disposed radially from the central axis to a peripheral edge, the cuvette having a top wall, a bottom wall, and side walls; a first barrier projecting into the cuvette from the bottom wall and defining a boundary between the first and second chambers; a second barrier projecting into the cuvette from the bottom wall and defining a boundary between the second and third chambers; first, second and third ports disposed through the top wall of the cuvette above the first, second and third chambers, respectively; a first deflector disposed between the first and second ports, projecting into the cuvette from the top wall and connected to the top wall of the cuvette; a second deflector disposed between the second and third ports, projecting into the cuvette from the top wall and connected to the top wall of the cuvette; at least one vessel having top, bottom and side walls, the at least one vessel disposed arcuately around the central axis a predetermined distance from the at least one cuvette; at least one common side wall separating the at least one vessel from the at least one cuvette; and a fourth port disposed through the top wall of the at least one vessel. 2. A cuvette rotor as set forth in claim 1, wherein the at least one cuvette includes a plurality of cuvettes arcuately arranged about the central axis, and the at least one vessel includes a plurality of vessels arcuately arranged about the central axis.
SUMMARY OF THE INVENTION The invention has the object of providing a cuvette rotor in which each cuvette has three chambers and there is the option of subjecting the reaction mixture to photometry both at a given fixed and at a variable path length. Furthermore, the intention is to arrange on the rotor other chambers, independent of the separate cuvettes, for dilution of samples. The object is achieved by a cuvette rotor wherein the cuvettes are bounded in their radial dimension by side walls which are essentially parallel to one another and by an upper part and a lower part, and have three chambers separated by barriers arranged on the lower part, there being, projecting into the central and into the peripherally arranged chamber, in each case at least one deflector fixed to the upper part. A vessel which is closed on all sides is formed between each of the separate cuvettes and its interior is connected to an opening in the upper part.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a top view of a segment of the cuvette rotor in accordance with the present invention;
DESCRIPTION OF THE PREFERRED EMBODIMENTS As shown in FIG. 1, the cuvette rotor 20 comprises cuvettes 10 which are closed on all sides and are bounded by walls 21, 22 which are essentially parallel to one another, and by an upper part 16 and a lower part 15, shown in FIG. 2. The separate cuvettes 10 each have three chambers 1, 2, 3 which are separated from one another by barriers 11, 12. The barriers 11, 12 are arranged on the lower part 15. The barriers 11, 12 are designed so that, on the one hand, at the required chamber volume no overflow into the adjacent chamber can take place and, on the other hand, on centrifugation there is formation of a breakaway edge which has a beneficial effect on the mixing of the reactants. The upper part 16 is provided with openings 4, 5, 6 through which the interior of the chambers 1, 2, 3 is accessible. Furthermore, deflectors 13, 14 are arranged on the upper part 16 (FIG. 2) and project into the central chamber 2 and into the peripherally arranged chamber 3. The deflectors 13, 14 prevent fluid which is running along the underside of the upper part 16 from emerging through the openings 5 and 6. Moreover, further breakaway edges are produced and have a beneficial effect on the mixing of the reactants. The space between the individual cuvettes 10 is designed as closed vessel 9 for dilution of the samples. Its interior is accessible via opening 8 in the upper part 16 (FIG. 3). In order to keep the amount of sample small, the peripherally arranged chamber 3 can have sections 7, 19 and 23 of different cross-section, with the cross-section of section 7 being only a fraction of the cross-section of section 23. The reduction in cross-section is essentially achieved by tapering the section 19 in the peripheral direction. In section 7 the walls 21, 23 and the upper and lower part are again aligned parallel to one another. Section 7 is used as measuring space for a constant path length of the sample on axial measurement and a variable path length on radial measurement (FIG. 4). In the region of section 7 the upper part 16 and lower part 15, and the front wall 24, of the cuvettes 10 are designed as optical windows. It is furthermore possible for the deflector 14 to be designed as deviation device for light. The path of the light ray for the measurement in the axial and radial direction is depicted in FIG. 4. 18 and 18' indicate the light emitters, 17 and 17' indicate the light receivers and 14 indicates the deflector designed as deviation device for light. It is, of course, also possible to interchange the light emitters and light receivers. To improve the mixing of the reactants, the peripherally arranged chamber 3 can be separated from the central chamber 2 by two barriers which face one another at a small distance. The rotary movement of the cuvette rotor causes the reactants, which are initially separate, to move radially in the direction of the front wall 24, thereby to flow over the barriers 11, 12 and to mix with one another. Finally, the mixture fills section 7 of the cuvette 10.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS4314970 *Aug 27, 1980Feb 9, 1982Instrumentation Laboratory Inc.Analysis systemUS4456581 *Nov 20, 1981Jun 26, 1984Boehringer Mannheim GmbhCentrifugal analyzer rotor unit and insert elementsUS4580897 *May 31, 1984Apr 8, 1986Allied CorporationCentrifugal analyzer rotorsUS4580898 *May 31, 1984Apr 8, 1986Allied CorporationAnalytical systemUS4902479 *Nov 7, 1983Feb 20, 1990Fisher Scientific CompanyCentrifugal analyzer rotorDE3340505A1 *Nov 9, 1983May 23, 1985Schumacher KgCell for receiving substances in spectrophotometryEP0163038A2 *Mar 25, 1985Dec 4, 1985Fisher Scientific CompanyCentrifugal analyzer rotors* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS5360597 *Mar 22, 1993Nov 1, 1994Eastman Kodak CompanyRibbed mechanism for mixing sample by vibrationUS5538691 *Jun 25, 1993Jul 23, 1996Daikin Industries, Ltd.Reaction vessel for optical measurementUS5580790 *Oct 21, 1994Dec 3, 1996Chiron CorporationMethod and apparatus for processing fluidsUS5814279 *Feb 2, 1996Sep 29, 1998Fresenius AgCentrifuge having marker elementsUS6348176 *Feb 11, 1999Feb 19, 2002Careside, Inc.Cartridge-based analytical instrument using centrifugal force/pressure for metering/transport of fluidsUS6506344Dec 10, 1999Jan 14, 2003Dade Behring Marburg GmbhMulti-cell rotorUS6653122Apr 24, 2001Nov 25, 2003Dade Microscan Inc.Indentification test device in a random access microbiological analyzerUS7790468 *Mar 4, 2005Sep 7, 2010Brother Kogyo Kabushiki KaishaTest object receptacle, test apparatus, and test methodUS8596150 *Jun 30, 2009Dec 3, 2013Panasonic CorporationAnalytical device with mixing cavityUS20110126646 *Jun 30, 2009Jun 2, 2011Panasonic CorporationAnalytical deviceEP0847529A1 *Aug 27, 1996Jun 17, 1998First Medical, Inc.Analytical rotor and method for detecting analytes in liquid samplesEP1062495A1 *Feb 17, 1999Dec 27, 2000Robert Aaron LevineCalibration of a whole blood sample analyser* Cited by examinerClassifications U.S. Classification422/72, 436/177, 436/45, 436/180, 422/64, 422/547International ClassificationG01N21/07, G01N35/02Cooperative ClassificationG01N21/07European ClassificationG01N21/07Legal EventsDateCodeEventDescriptionFeb 26, 2009ASAssignmentOwner name: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH, GERMFree format text: CHANGE OF NAME;ASSIGNOR:DADE BEHRING MARBURG GMBH;REEL/FRAME:022309/0627Effective date: 20080829Owner name: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH,GERMAFree format text: CHANGE OF NAME;ASSIGNOR:DADE BEHRING MARBURG GMBH;REEL/FRAME:22309/627May 16, 2006ASAssignmentOwner name: DADE BEHRING MARBURG GMBH, GERMANYFree format text: RELEASE OF SECURITY INTEREST;ASSIGNOR:DRESDNER BANK AKTIENGESELLSCHAFT IN FRANKFURT AM MAIN;REEL/FRAME:017675/0358Effective date: 20060407Aug 16, 2004FPAYFee paymentYear of fee payment: 12Dec 14, 2001ASAssignmentOwner name: DRESDNER BANK AKTIENGESELLSCHAFT IN FRANKFURT AM MFree format text: GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS, TRADEMARKS AND OTHER INTELLECTUAL PROPERTY RIGHTS;ASSIGNOR:DADE BEHRING MARBURG GMBH;REEL/FRAME:012333/0714Effective date: 20011019Free format text: GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS, TRADEMARKS AND OTHER INTELLECTUAL PROPERTY RIGHTS;ASSIGNOR:DADE BEHRING MARBURG GMBH /AR;REEL/FRAME:012333/0714Aug 15, 2000FPAYFee paymentYear of fee payment: 8Sep 4, 1997ASAssignmentOwner name: BEHRING DIAGNOSTICS GMBH, GERMANYFree format text: ;ASSIGNOR:BEHRINGWERKE AKTIENGESELLSCHAFT;REEL/FRAME:008792/0076Effective date: 19970731Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BEHRINGWERKE AKTIENGESELLSCHAFT;REEL/FRAME:008842/0428Aug 1, 1996FPAYFee paymentYear of fee payment: 4Feb 1, 1994CCCertificate of correctionMay 30, 1990ASAssignmentOwner name: BEHRINGWERKE AKTIENGESELLSCHAFT, A CORP. OF FEDERAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNORS:BOUCHEE, BERNHARD;FICKENSCHER, KARL;REEL/FRAME:005326/0028;SIGNING DATES FROM 19900424 TO 19900430RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google