Source: https://online.epocrates.com/u/10a1701/enoxaparin?ICID=EMN_LP_0810
Timestamp: 2014-03-11 18:34:19
Document Index: 174726809

Matched Legal Cases: ['art: 12', 'art 12', 'art: 12', 'art: 2', 'art: 30', 'art: 30']

enoxaparin Entire Monograph - Epocrates Online
may occur in anticoagulated pts receiving neuraxial anesthesia or spinal puncture; hematoma may result in long-term or permanent paralysis; incr. hematoma risk if indwelling epidural catheter use, concomitant use of drugs affecting hemostasis incl. NSAIDs, platelet inhibitors or other anticoagulants, traumatic or repeated epidural/spinal puncture hx, spinal deformity, or spinal surgery hx; weigh risk/benefit before neuraxial intervention in anticoagulated pts or planned anticoagulation for thromboprophylaxis; while optimal timing to minimize risk is unknown, delay spinal catheter placement or removal >12h after prophylactic doses and >24h after tx doses; consider delaying post-procedural dose >4h after catheter removal; for pts w/ CrCl <30, consider delaying spinal catheter placement or removal >24h after prophylactic doses and >48h after tx doses; monitor s/sx neurologic impairment frequently, treat urgently if needed
Dosage forms: SC; IV
DVT prophylaxis, hip replacement
[30 mg SC q12h x7-10 days]
Start: 12-24h postop; Alt: 40 mg SC qd x7-10 days, start 12h preop; Info: may cont. 40 mg SC qd x3wk as extended prophylaxis; D/C if Plt <100k
DVT prophylaxis, knee replacement
Start: 12-24h postop; Info: D/C if Plt <100k
DVT prophylaxis, abdominal surgery
[40 mg SC qd x7-10 days]
Start: 2h preop; Info: D/C if Plt <100k
DVT prophylaxis, restricted mobility
[40 mg SC qd x6-11 days]
Info: D/C if Plt <100k
DVT/PE tx, inpatient
[1 mg/kg SC q12h]
Alt: 1.5 mg/kg SC qd; Info: cont. for >5 days and overlap w/ warfarin until INR 2-3; D/C if Plt <100k
DVT w/o PE tx, outpatient
Info: cont. for >5 days and overlap w/ warfarin until INR 2-3; D/C if Plt <100k
Info: for ischemic complications prophylaxis; give w/ aspirin; cont. for >2 days until pt stabilized; D/C if Plt <100k
STEMI, acute
[thrombolytic adjunct, <75 yo]
Dose: 1 mg/kg SC q12h; Start: 30 mg IV plus 1 mg/kg SC x1, between 15min before and 30min after starting thrombolytic; Max: 100 mg/dose for first 2 SC doses; Info: give w/ aspirin; cont. for 8 days or until hospital D/C, optimal tx duration unknown; D/C if Plt <100k
[thrombolytic adjunct, >75 yo]
Dose: 0.75 mg/kg SC q12h; Start: between 15min before and 30min after starting thrombolytic; Max: 75 mg/dose for first 2 doses; Info: give w/ aspirin; cont. for 8 days or until hospital D/C, optimal tx duration unknown; D/C if Plt <100k
[PCI adjunct, <75 yo]
Dose: 1 mg/kg SC q12h; Start: 30 mg IV plus 1 mg/kg SC x1; Max: 100 mg/dose for first 2 SC doses; Info: give 0.3 mg/kg IV x1 if last dose >8h before PCI; D/C if Plt <100k
[PCI adjunct, >75 yo]
Dose: 0.75 mg/kg SC q12h; Max: 75 mg/dose for first 2 doses; Info: give 0.3 mg/kg IV x1 if last dose >8h before PCI; D/C if Plt <100k
CrCl <30: 30 mg SC qd; HD/PD: no supplement
[DVT tx, unstable angina, NQWMI]
CrCl <30: 1 mg/kg SC qd; HD/PD: no supplement
[STEMI, <75 yo]
CrCl <30: 30 mg IV plus 1 mg/kg SC x1, then 1 mg/kg SC qd; HD/PD: no supplement
[STEMI, >75 yo]
Dosage forms: SC *thromboembolism prophylaxis
[<2 mo]
Dose: 0.75 mg/kg SC q12h; Info: adjust dose to anti-Xa levels 0.1-0.3 units/mL; D/C if Plt <100k
[>2 mo]
Dose: 0.5 mg/kg SC q12h; Info: adjust dose to anti-Xa levels 0.1-0.3 units/mL; D/C if Plt <100k
*thromboembolism tx
Dose: 1.5 mg/kg SC q12h; Info: adjust dose to anti-Xa levels 0.5-1 units/mL; D/C if Plt <100k
Dose: 1 mg/kg SC q12h; Info: adjust dose to anti-Xa levels 0.5-1 units/mL; D/C if Plt <100k
CrCl 10-29: decr. dose 30% or give q24h; CrCl <10: decr. dose 50%, give q24h; HD/PD: no supplement
hypersens. to pork products
hypersens. to benzyl alcohol (mutidose vial form)
thrombocytopenia hx, enoxaparin-assoc.
caution in pregnant pts w/ mechanical heart valve
caution if wt <45 kg (female pts) or <57 kg (male pts)
caution if BMI >30 kg/m^2
caution if heparin-induced thrombocytopenia
caution if recent surgery or trauma
caution if active GI ulcer or dz
caution if HTN, uncontrolled
caution if hemorrhagic stroke
caution if diabetic retinopathy
caution if endocarditis, acute
enoxaparin (generic)+mifepristone 1 interactionsContraindicated enoxaparin + mifepristonecontraindicated if pregnancy termination use; caution advised if daily mifepristone use in female pts: combo may incr. risk of severe or prolonged vaginal bleeding (additive effects) Avoid/Use Alternative
enoxaparin (generic)+abciximab 1 interactionsAvoid/Use Alternative enoxaparin + abciximabweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) anagrelide
enoxaparin (generic)+anagrelide 1 interactionsAvoid/Use Alternative enoxaparin + anagrelideweigh risk/benefit: combo may incr. risk of bleeding (additive effects) antithrombin
enoxaparin (generic)+antithrombin 1 interactionsAvoid/Use Alternative enoxaparin + antithrombinweigh risk/benefit: combo may incr. risk of bleeding (additive effects) apixaban
enoxaparin (generic)+apixaban 1 interactionsAvoid/Use Alternative enoxaparin + apixabanweigh risk/benefit: combo may incr. risk of bleeding (additive effects) argatroban
enoxaparin (generic)+argatroban 1 interactionsAvoid/Use Alternative enoxaparin + argatrobanweigh risk/benefit: combo may incr. risk of bleeding (additive effects) aspirin
enoxaparin (generic)+aspirin 1 interactionsAvoid/Use Alternative enoxaparin + aspirinweigh risk/benefit, low dose ASA OK: combo w/ aspirin may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) bivalirudin
enoxaparin (generic)+bivalirudin 1 interactionsAvoid/Use Alternative enoxaparin + bivalirudinweigh risk/benefit; discontinue unfractionated heparin 30min prior, low-molecular wt heparins 8h prior: concurrent admin. may incr. risk of bleeding (additive effects) cilostazol
enoxaparin (generic)+cilostazol 1 interactionsAvoid/Use Alternative enoxaparin + cilostazolweigh risk/benefit: combo may incr. risk of bleeding (additive effects) clopidogrel
enoxaparin (generic)+clopidogrel 1 interactionsAvoid/Use Alternative enoxaparin + clopidogrelweigh risk/benefit: combo may incr. risk of bleeding (additive effects) dabigatran etexilate
enoxaparin (generic)+dabigatran etexilate 1 interactionsAvoid/Use Alternative enoxaparin + dabigatran etexilateweigh risk/benefit: combo may incr. risk of bleeding (additive effects) danshen
enoxaparin (generic)+danshen 1 interactionsAvoid/Use Alternative enoxaparin + danshenavoid combo: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) desirudin
enoxaparin (generic)+desirudin 1 interactionsAvoid/Use Alternative enoxaparin + desirudinavoid combo: combo may incr. risk of bleeding (additive effects) diclofenac
enoxaparin (generic)+diclofenac 1 interactionsAvoid/Use Alternative enoxaparin + diclofenacweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) diflunisal
enoxaparin (generic)+diflunisal 1 interactionsAvoid/Use Alternative enoxaparin + diflunisalweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) dipyridamole
enoxaparin (generic)+dipyridamole 1 interactionsAvoid/Use Alternative enoxaparin + dipyridamoleweigh risk/benefit: combo may incr. risk of bleeding (additive effects) drotrecogin alfa
enoxaparin (generic)+drotrecogin alfa 1 interactionsAvoid/Use Alternative enoxaparin + drotrecogin alfaweigh risk/benefit if concurrent heparin >15 units/kg/h or anticoagulants w/in 7 days prior to drotrecogin alfa: combo may incr. risk of bleeding (additive effects) eptifibatide
enoxaparin (generic)+eptifibatide 1 interactionsAvoid/Use Alternative enoxaparin + eptifibatideweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) etodolac
enoxaparin (generic)+etodolac 1 interactionsAvoid/Use Alternative enoxaparin + etodolacweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) fenoprofen
enoxaparin (generic)+fenoprofen 1 interactionsAvoid/Use Alternative enoxaparin + fenoprofenweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) flurbiprofen
enoxaparin (generic)+flurbiprofen 1 interactionsAvoid/Use Alternative enoxaparin + flurbiprofenweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) fondaparinux
enoxaparin (generic)+fondaparinux 1 interactionsAvoid/Use Alternative enoxaparin + fondaparinuxweigh risk/benefit: combo may incr. risk of bleeding (additive effects) ibritumomab tiuxetan
enoxaparin (generic)+ibritumomab tiuxetan 1 interactionsAvoid/Use Alternative enoxaparin + ibritumomab tiuxetanweigh risk/benefit, monitor platelets: combo may incr. risk of bleeding (additive effects, ibritumomab induces severe prolonged thrombocytopenia) ibuprofen
enoxaparin (generic)+ibuprofen 1 interactionsAvoid/Use Alternative enoxaparin + ibuprofenweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) ibuprofen lysine
enoxaparin (generic)+ibuprofen lysine 1 interactionsAvoid/Use Alternative enoxaparin + ibuprofen lysineweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) indomethacin
enoxaparin (generic)+indomethacin 1 interactionsAvoid/Use Alternative enoxaparin + indomethacinweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) ketoprofen
enoxaparin (generic)+ketoprofen 1 interactionsAvoid/Use Alternative enoxaparin + ketoprofenweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) ketorolac
enoxaparin (generic)+ketorolac 1 interactionsAvoid/Use Alternative enoxaparin + ketorolacweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) lepirudin
enoxaparin (generic)+lepirudin 1 interactionsAvoid/Use Alternative enoxaparin + lepirudinweigh risk/benefit: combo may incr. risk of bleeding (additive effects) meclofenamate
enoxaparin (generic)+meclofenamate 1 interactionsAvoid/Use Alternative enoxaparin + meclofenamateweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) mefenamic acid
enoxaparin (generic)+mefenamic acid 1 interactionsAvoid/Use Alternative enoxaparin + mefenamic acidweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) meloxicam
enoxaparin (generic)+meloxicam 1 interactionsAvoid/Use Alternative enoxaparin + meloxicamweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) nabumetone
enoxaparin (generic)+nabumetone 1 interactionsAvoid/Use Alternative enoxaparin + nabumetoneweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) naproxen
enoxaparin (generic)+naproxen 1 interactionsAvoid/Use Alternative enoxaparin + naproxenweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) omacetaxine mepesuccinate
enoxaparin (generic)+omacetaxine mepesuccinate 1 interactionsAvoid/Use Alternative enoxaparin + omacetaxine mepesuccinateavoid combo if Plt <50,000: combo may incr. risk of bleeding (additive effects, omacetaxine mepesuccinate induces severe thrombocytopenia) oxaprozin
enoxaparin (generic)+oxaprozin 1 interactionsAvoid/Use Alternative enoxaparin + oxaprozinweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) piroxicam
enoxaparin (generic)+piroxicam 1 interactionsAvoid/Use Alternative enoxaparin + piroxicamweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) prasugrel
enoxaparin (generic)+prasugrel 1 interactionsAvoid/Use Alternative enoxaparin + prasugrelweigh risk/benefit: combo may incr. risk of bleeding (additive effects) rivaroxaban
enoxaparin (generic)+rivaroxaban 1 interactionsAvoid/Use Alternative enoxaparin + rivaroxabanweigh risk/benefit: combo may incr. risk of bleeding (additive effects) sulindac
enoxaparin (generic)+sulindac 1 interactionsAvoid/Use Alternative enoxaparin + sulindacweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) ticagrelor
enoxaparin (generic)+ticagrelor 1 interactionsAvoid/Use Alternative enoxaparin + ticagrelorweigh risk/benefit: combo may incr. risk of bleeding (additive effects) ticlopidine
enoxaparin (generic)+ticlopidine 1 interactionsAvoid/Use Alternative enoxaparin + ticlopidineweigh risk/benefit: combo may incr. risk of bleeding (additive effects) tirofiban
enoxaparin (generic)+tirofiban 1 interactionsAvoid/Use Alternative enoxaparin + tirofibanweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) tolmetin
enoxaparin (generic)+tolmetin 1 interactionsAvoid/Use Alternative enoxaparin + tolmetinweigh risk/benefit: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) tositumomab
enoxaparin (generic)+tositumomab 1 interactionsAvoid/Use Alternative enoxaparin + tositumomabweigh risk/benefit, monitor platelets: combo may incr. risk of bleeding (additive effects, tositumomab induces severe prolonged thrombocytopenia) warfarin
enoxaparin (generic)+warfarin 1 interactionsAvoid/Use Alternative enoxaparin + warfarinweigh risk/benefit, monitor INR when overlapping therapy: combo may incr. risk of bleeding; heparin in high concentrations may alter INR (additive effects) Monitor/Modify Tx
enoxaparin (generic)+chamomile, German 1 interactionsMonitor/Modify Tx enoxaparin + chamomile, Germancaution advised w/ large doses of German chamomile: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) Therapeutic Advantage
enoxaparin (generic)+protamine sulfate 1 interactionsTherapeutic Advantage enoxaparin + protamine sulfateuse for therapeutic advantage to reverse anticoagulation: combo neutralizes anti-Xa activity of heparins (antagonistic effects, binds heparin to form stable complex) Caution Advised
enoxaparin (generic)+alteplase 1 interactionsCaution Advised enoxaparin + alteplasecaution advised: combo may incr. risk of bleeding (additive effects) alteplase intracatheter
enoxaparin (generic)+alteplase intracatheter 1 interactionsCaution Advised enoxaparin + alteplase intracathetercaution advised: combo may incr. risk of bleeding (additive effects) celecoxib
enoxaparin (generic)+celecoxib 1 interactionsCaution Advised enoxaparin + celecoxibcaution advised: combo may incr. risk of GI bleeding (additive effects) chondroitin
enoxaparin (generic)+chondroitin 1 interactionsCaution Advised enoxaparin + chondroitincaution advised w/ high-dose glucosamine (3 g/day) plus high-dose chondroitin (2.4 g/day): combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) citalopram
enoxaparin (generic)+citalopram 1 interactionsCaution Advised enoxaparin + citalopramcaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) collagenase clostridium histolyticum
enoxaparin (generic)+collagenase clostridium histolyticum 1 interactionsCaution Advised enoxaparin + collagenase clostridium histolyticumcaution advised: combo may incr. risk of bleeding (additive effects) dasatinib
enoxaparin (generic)+dasatinib 1 interactionsCaution Advised enoxaparin + dasatinibcaution advised: combo may incr. risk of bleeding (additive effects) deferasirox
enoxaparin (generic)+deferasirox 1 interactionsCaution Advised enoxaparin + deferasiroxcaution advised: combo may incr. risk of GI bleeding (additive effects) desvenlafaxine
enoxaparin (generic)+desvenlafaxine 1 interactionsCaution Advised enoxaparin + desvenlafaxinecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) diclofenac topical
enoxaparin (generic)+diclofenac topical 1 interactionsCaution Advised enoxaparin + diclofenac topicalcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects, up to 10% systemic absorption of diclofenac topical; minimal absorption w/ patch) dong quai
enoxaparin (generic)+dong quai 1 interactionsCaution Advised enoxaparin + dong quaicaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) duloxetine
enoxaparin (generic)+duloxetine 1 interactionsCaution Advised enoxaparin + duloxetinecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) escitalopram
enoxaparin (generic)+escitalopram 1 interactionsCaution Advised enoxaparin + escitalopramcaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) evening primrose oil
enoxaparin (generic)+evening primrose oil 1 interactionsCaution Advised enoxaparin + evening primrose oilcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) fenugreek
enoxaparin (generic)+fenugreek 1 interactionsCaution Advised enoxaparin + fenugreekcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) feverfew
enoxaparin (generic)+feverfew 1 interactionsCaution Advised enoxaparin + feverfewcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) fish oils
enoxaparin (generic)+fish oils 1 interactionsCaution Advised enoxaparin + fish oilscaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) flaxseed
enoxaparin (generic)+flaxseed 1 interactionsCaution Advised enoxaparin + flaxseedcaution advised w/ flaxseed oil: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) fluoxetine
enoxaparin (generic)+fluoxetine 1 interactionsCaution Advised enoxaparin + fluoxetinecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) fluvoxamine
enoxaparin (generic)+fluvoxamine 1 interactionsCaution Advised enoxaparin + fluvoxaminecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) garlic
enoxaparin (generic)+garlic 1 interactionsCaution Advised enoxaparin + garliccaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) ginger
enoxaparin (generic)+ginger 1 interactionsCaution Advised enoxaparin + gingercaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) ginkgo
enoxaparin (generic)+ginkgo 1 interactionsCaution Advised enoxaparin + ginkgocaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) ginseng, Asian
enoxaparin (generic)+ginseng, Asian 1 interactionsCaution Advised enoxaparin + ginseng, Asiancaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) ginseng, Siberian
enoxaparin (generic)+ginseng, Siberian 1 interactionsCaution Advised enoxaparin + ginseng, Siberiancaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) glucosamine
enoxaparin (generic)+glucosamine 1 interactionsCaution Advised enoxaparin + glucosaminecaution advised w/ high-dose glucosamine (3 g/day) plus high-dose chondroitin (2.4 g/day): combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) goldenseal
enoxaparin (generic)+goldenseal 1 interactionsCaution Advised enoxaparin + goldensealcaution advised: combo may inhibit anticoagulant effects of heparins (antagonistic effects) green tea
enoxaparin (generic)+green tea 1 interactionsCaution Advised enoxaparin + green teacaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) horse chestnut seed
enoxaparin (generic)+horse chestnut seed 1 interactionsCaution Advised enoxaparin + horse chestnut seedcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) icosapent ethyl
enoxaparin (generic)+icosapent ethyl 1 interactionsCaution Advised enoxaparin + icosapent ethylcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) iloprost inhaled
enoxaparin (generic)+iloprost inhaled 1 interactionsCaution Advised enoxaparin + iloprost inhaledcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) levomilnacipran
enoxaparin (generic)+levomilnacipran 1 interactionsCaution Advised enoxaparin + levomilnaciprancaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) milnacipran
enoxaparin (generic)+milnacipran 1 interactionsCaution Advised enoxaparin + milnaciprancaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) omega-3-acid
enoxaparin (generic)+omega-3-acid 1 interactionsCaution Advised enoxaparin + omega-3-acidcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) paroxetine
enoxaparin (generic)+paroxetine 1 interactionsCaution Advised enoxaparin + paroxetinecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) piperacillin
enoxaparin (generic)+piperacillin 1 interactionsCaution Advised enoxaparin + piperacillincaution advised: combo may incr. risk of bleeding; extended-spectrum penicillins may cause hypoprothrombinemia (additive effects) porfimer
enoxaparin (generic)+porfimer 1 interactionsCaution Advised enoxaparin + porfimercaution advised: combo may decr. efficacy of photodynamic tx; anticoagulants may decr. thromboxane A2-mediated tumor necrosis (antagonistic effects) red clover
enoxaparin (generic)+red clover 1 interactionsCaution Advised enoxaparin + red clovercaution advised w/ large amounts of red clover: combo may incr. risk of bleeding (additive effects, red clover has coumarin constituents) reteplase
enoxaparin (generic)+reteplase 1 interactionsCaution Advised enoxaparin + reteplasecaution advised: combo may incr. risk of bleeding (additive effects) sertraline
enoxaparin (generic)+sertraline 1 interactionsCaution Advised enoxaparin + sertralinecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) sibutramine
enoxaparin (generic)+sibutramine 1 interactionsCaution Advised enoxaparin + sibutraminecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) temsirolimus
enoxaparin (generic)+temsirolimus 1 interactionsCaution Advised enoxaparin + temsirolimuscaution advised: combo may incr. risk of cerebral hemorrhage, incl. fatal outcomes (mechanism unknown, possible additive effects) tenecteplase
enoxaparin (generic)+tenecteplase 1 interactionsCaution Advised enoxaparin + tenecteplasecaution advised: combo may incr. risk of bleeding (additive effects) ticarcillin
enoxaparin (generic)+ticarcillin 1 interactionsCaution Advised enoxaparin + ticarcillincaution advised: combo may incr. risk of bleeding; extended-spectrum penicillins may cause hypoprothrombinemia (additive effects) tipranavir
enoxaparin (generic)+tipranavir 1 interactionsCaution Advised enoxaparin + tipranavircaution advised: combo may incr. risk of bleeding (additive effects, tipranavir has antiplatelet effects) trazodone
enoxaparin (generic)+trazodone 1 interactionsCaution Advised enoxaparin + trazodonecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) treprostinil
enoxaparin (generic)+treprostinil 1 interactionsCaution Advised enoxaparin + treprostinilcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) treprostinil inhaled
enoxaparin (generic)+treprostinil inhaled 1 interactionsCaution Advised enoxaparin + treprostinil inhaledcaution advised: combo may incr. risk of bleeding (additive anticoagulant/antiplatelet effects) venlafaxine
enoxaparin (generic)+venlafaxine 1 interactionsCaution Advised enoxaparin + venlafaxinecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) vilazodone
enoxaparin (generic)+vilazodone 1 interactionsCaution Advised enoxaparin + vilazodonecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) vortioxetine
enoxaparin (generic)+vortioxetine 1 interactionsCaution Advised enoxaparin + vortioxetinecaution advised: combo may incr. risk of bleeding (synergistic effects, anticoagulant/antiplatelet effects augmented by inhibition of platelet serotonin uptake) willow bark
enoxaparin (generic)+willow bark 1 interactionsCaution Advised enoxaparin + willow barkcaution advised: combo may incr. risk of bleeding (additive effects, willow bark may contain salicylates) Adverse Reactions
hemorrhage, major
thrombocytopenia w/ thrombosis
Cr at baseline; CBC; Plt; stool occult blood tests; anti-Xa levels if significant renal impairment, in peds, and in pregnancy w/ mechanical prosthetic heart valve
enoxaparin confused with: dalteparin; enoxacin; fluvoxamine; Fragmin
Metabolism: liver primarily; CYP450: unknown
Excretion: urine 40%; Half-life: 4.5-7h Subclass: Anticoagulants	Mechanism of Actionbinds to antithrombin III and accelerates activity, inhibiting thrombin and factor Xa (low-molecular weight heparin)	Manufacturer/Pricing
from http://www.goodrx.com/enoxaparin
120 mg/0.8 mL (5 mL): $492.35
40 mg/0.4 mL (5 mL): $152.32
30 mg/0.3 mL (5 mL): $133.25
60 mg/0.6 mL (5 mL): $264.99
80 mg/0.8 mL (5 mL): $272.59
100 mg/mL (5 mL): $409.40
150 mg/mL (5 mL): $630.09
60 mg/0.6 mL (1 carton, 10 syringes): $508.00
80 mg/0.8 mL (1 carton, 10 syringes): $699.99
30 mg/0.3 mL (1 carton, 10 syringes): $299.99
120 mg/0.8 mL (1 carton, 10 syringes): $999.99
40 mg/0.4 mL (1 carton, 10 syringes): $369.99
100 mg/mL (1 carton, 10 syringes): $849.99
150 mg/mL (1 carton, 10 syringes): $1,319.89