Source: https://patents.google.com/patent/US8594785B2/en
Timestamp: 2019-06-27 06:56:13
Document Index: 614845870

Matched Legal Cases: ['Application No. 2677122', 'Application No. 2008210293', 'Application No. 08728869', 'Application No. 2008210293', 'Application No. 2008210293', 'Application No. 2009']

US8594785B2 - Neurostimulation system and method for measuring patient activity - Google Patents
Neurostimulation system and method for measuring patient activity Download PDF
US8594785B2
US8594785B2 US12/024,947 US2494708A US8594785B2 US 8594785 B2 US8594785 B2 US 8594785B2 US 2494708 A US2494708 A US 2494708A US 8594785 B2 US8594785 B2 US 8594785B2
US12/024,947
US20080188909A1 (en
2007-02-01 Priority to US88779407P priority Critical
2008-02-01 Application filed by Boston Scientific Neuromodulation Corp filed Critical Boston Scientific Neuromodulation Corp
2008-02-01 Priority to US12/024,947 priority patent/US8594785B2/en
2008-08-07 Publication of US20080188909A1 publication Critical patent/US20080188909A1/en
2008-08-19 Assigned to BOSTON SCIENTIFIC NEUROMODULATION CORPORATION reassignment BOSTON SCIENTIFIC NEUROMODULATION CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BRADLEY, KERRY
2013-11-26 Publication of US8594785B2 publication Critical patent/US8594785B2/en
Electrical energy is conveyed via an implanted tissue stimulation system into tissue of the patient over a period of time. Electrical parameter data (e.g., impedance data and/or field potential data) is measured based on the electrical energy conveyed into the tissue of the patient, whereby the electrical parameter data is modulated in response to the physical activity of the patient to generate a time-varying signal (e.g., an oscillating signal). The time-varying signal is analyzed, and the physical activity of the patient (e.g., the physical activity level of the patient or the physical events performed by the patient) is tracking during the time period based on the analyzed time-varying signal.
The IPG 16 is capable of directing electrical stimulation energy to each of the electrodes 20. To that end, the electrodes 20 of the first lead 12 are electrically connected to the IPG 16 by respective signal wires 24 (some of which are not shown) that extend through, or are embedded in, the associated flexible lead body 22. Similarly, the electrodes 20 of the second lead 14 are electrically connected to the IPG 16 by respective wires 26 (some of which are not shown). The signal wires 24, 26 are connected to the IPG 16 by way of an interface 28. The interface 28 may be any suitable device that allows the leads 12, 14 to be removably or permanently electrically connected to the IPG 16. Such an interface may, for example, be an electro-mechanical connector arrangement including lead connectors 30 a, 30 b within the IPG 16 that are configured to mate with corresponding connectors (only connector 32 a is shown) on the corresponding leads 12, 14. Alternatively, the leads 12, 14 can share a single connector that mates with a corresponding connector on the IPG 16. Exemplary connector arrangements are disclosed in U.S. Pat. Nos. 6,609,029 and 6,741,892, which are incorporated herein by reference. The IPG 16 includes an outer case 34 formed from an electrically conductive, biocompatible material, such as titanium and, in some instances, will function as an electrode. The case 34 forms a hermetically sealed compartment wherein the electronic and other components (described in further detail below) are protected from the body tissue and fluids.
Measuring electrode impedance is important, because implanted electrical stimulation systems depend upon the stability of the devices to be able to convey electrical stimulation pulses of known energy to the target tissue to be excited. The target tissue represents a known electrical load into which the electrical energy associated with the stimulation pulse is to be delivered. If the impedance is too high, that suggests the connector 32 a and/or lead 12, 14, which connect with the electrode 20 may be open or broken. If the impedance is too low, that suggests that there may be a short circuit somewhere in the connector 32 a and/or lead 12, 14. In either event (too high or too low impedance), the IPG 16 may be unable to perform its intended function.
conveying time-varying electrical energy having an envelope from an implanted tissue stimulation device into tissue of the patient over a period of time, whereby the envelope of the electrical energy is modulated in response to physical activity of the patient;
deriving a time-varying signal containing electrical parameter data from the modulated time-varying electrical energy;
analyzing the time-varying signal; and
tracking the physical activity of the patient during the time period based on the analyzed time-varying signal, wherein the tracked physical activity is indicative of the efficacy of the therapy provided to the patient.
2. The method of claim 1, wherein the electrical energy conveyed from the tissue stimulation device provides therapy to the patient.
3. The method of claim 1, wherein the electrical parameter data is one or both of electrical impedance data or field potential data.
4. The method of claim 1, wherein the time-varying signal analysis comprises determining a magnitude of the time-varying signal.
5. The method of claim 4, wherein the time-varying signal magnitude determination comprises detecting peak-to-peak amplitude values of the time-varying signal, detecting an energy of the time-varying signal, or detecting an envelope of the time-varying signal.
6. The method of claim 1, wherein the time-varying signal analysis comprises determining a morphology of the time-varying signal.
7. The method of claim 6, wherein the time-varying signal morphology determination comprises detecting an envelope of the time-varying signal.
8. The method of claim 1, wherein tracking the physical activity of the patient comprises tracking the physical activity level of the patient.
9. The method of claim 8, wherein determining the physical activity level of the patient comprises determining whether the physical activity level is relatively high or the physical activity level is relatively low.
10. The method of claim 1, wherein tracking the physical activity of the patient comprises tracking the different types of physical events performed by the patient.
11. The method of claim 10, wherein the different types of physical events performed by the patient comprise at least two of laying down, walking, jogging, jumping, sitting, and twisting.
12. The method of claim 10, wherein the different types of physical events are stored in a look-up table respectively correlated to previously measured reference electrical parameter data, wherein tracking the different types of physical events performed by the patient comprises comparing the measuring electrical parameter data to the reference electrical parameter data stored in the look-up table, and determining the different types of physical activity during the time period based on the comparison.
13. The method of claim 1, further comprising modifying therapy provided to the patient by the stimulation device based on the tracked physical activity.
14. The method of claim 1, wherein the time-varying signal is an oscillating signal.
15. The method of claim 1, further comprising determining whether the conveyed electrical energy is effective based on the tracked physical activity of the patient.
16. The method of claim 1, wherein tracking the physical activity of the patient comprises tracking the time that physical activity is performed by the patient.
17. The method of claim 16, wherein tracking the time that physical activity is performed by the patient comprises determining whether the physical activity is performed by the patient during a first time period of a 24-hour day or performed by the patient during a second time period of the 24-hour day.
18. The method of claim 17, wherein the first time period is a daytime and the second time period is a nighttime.
19. The method of claim 16, wherein tracking the time that physical activity is performed by the patient comprises determining whether the physical activity is Circadian in nature.
20. The method of claim 1, wherein the patient activity is indicative of whether the therapy provided to the patient treats pain.
21. The method of claim 1, wherein the patient activity is one or both of a footfall and a postural change.
22. The method of claim 1, wherein tracking the physical activity of the patient comprises tracking a time at which physical activity is performed by the patient.
23. A tissue stimulation system, comprising:
an implantable electrode lead;
an implantable electrical stimulation device configured for being coupled to the electrode lead, the electrical stimulation device configured for conveying time-varying electrical energy from the electrode lead into tissue of a patient over a period of time, the time-varying electrical energy having an envelope capable of being modulated in response to physical activity of the patient, the electrical stimulation device further configured for deriving a time-varying signal containing electrical parameter data from the electrical energy conveyed into the tissue of the patient; and
a processing device configured for analyzing the time-varying signal, and tracking the physical activity of the patient during the time period based on the analyzed time-varying signal, wherein the tracked physical activity is indicative of the efficacy of the therapy provided to the patient.
24. The system of claim 23, wherein the stimulation device is configured for conveying the electrical energy from the implanted from the electrode lead to provide therapy to the patient.
25. The system of claim 23, wherein the electrical parameter data is one or both of electrical impedance data or field potential data.
26. The system of claim 23, wherein the processing device is the stimulation device.
27. The system of claim 23, wherein the processing device is an external programmer configured for communicating with the stimulation device.
28. The system of claim 23, wherein the time-varying signal analysis comprises determining a magnitude of the time-varying signal.
29. The system of claim 28, wherein the time-varying signal magnitude determination comprises detecting peak-to-peak amplitude values of the time-varying signal, detecting an energy of the time-varying signal, or detecting an envelope of the time-varying signal.
30. The system of claim 23, wherein the time-varying signal analysis comprises determining a morphology of the time-varying signal.
31. The system of claim 30, wherein the time-varying signal morphology determination comprises detecting an envelope of the time-varying signal.
32. The system of claim 23, wherein tracking the physical activity of the patient comprises tracking the physical activity level of the patient.
33. The system of claim 32, wherein determining the physical activity level of the patient comprises determining whether the physical activity level is relatively high or the physical activity level is relatively low.
34. The system of claim 23, wherein tracking the physical activity of the patient comprises tracking the physical events performed by the patient.
35. The system of claim 34, wherein the different types of physical events performed by the patient comprise at least two of laying down, walking, jogging, jumping, sitting, and twisting.
36. The system of claim 34, further comprising a look-up table storing the different types of physical events respectively correlated to previously measured reference electrical parameter data, wherein tracking the different types of physical events performed by the patient comprises comparing the measuring electrical parameter data to the reference electrical parameter data stored in the look-up table, and determining the different types of physical activity during the time period based on the comparison.
37. The system of claim 23, wherein the time-varying signal is an oscillating signal.
38. The system of claim 23, wherein the processing device is further configured for determining whether the conveyed electrical energy is effective based on the tracked physical activity of the patient.
39. The system of claim 23, wherein tracking the physical activity of the patient comprises tracking the time that physical activity is performed by the patient.
40. The system of claim 39, wherein tracking the time that physical activity is performed by the patient comprises determining whether the physical activity is performed by the patient during a first time period of a 24-hour day or performed by the patient during a second time period of the 24-hour day.
41. The system of claim 40, wherein the first time period is a daytime and the second time period is a nighttime.
42. The system of claim 39, wherein tracking the time that physical activity is performed by the patient comprises determining whether the physical activity is Circadian in nature.
43. The system of claim 23, wherein the patient activity is indicative of whether the therapy provided to the patient treats pain.
44. The system of claim 23, wherein the patient activity is one or both of a footfall and a postural change.
45. The system of claim 23, wherein tracking the physical activity of the patient comprises tracking a time at which physical activity is performed by the patient.
US12/024,947 2007-02-01 2008-02-01 Neurostimulation system and method for measuring patient activity Active 2031-08-07 US8594785B2 (en)
US88779407P true 2007-02-01 2007-02-01
US12/024,947 US8594785B2 (en) 2007-02-01 2008-02-01 Neurostimulation system and method for measuring patient activity
US20080188909A1 US20080188909A1 (en) 2008-08-07
US8594785B2 true US8594785B2 (en) 2013-11-26
ID=39453407
US12/024,947 Active 2031-08-07 US8594785B2 (en) 2007-02-01 2008-02-01 Neurostimulation system and method for measuring patient activity
US (1) US8594785B2 (en)
EP (1) EP2114518B1 (en)
JP (1) JP5224478B2 (en)
AU (1) AU2008210293B2 (en)
CA (1) CA2677122C (en)
ES (1) ES2550960T3 (en)
WO (1) WO2008095185A1 (en)
US6714892B2 (en) 2001-03-12 2004-03-30 Agere Systems, Inc. Three dimensional reconstruction metrology
AT419898T (en) * 2005-04-11 2009-01-15 Medtronic Inc Displacement between electrode combinations in an electrical stimulation device
2008-02-01 WO PCT/US2008/052851 patent/WO2008095185A1/en active Application Filing
2008-02-01 ES ES08728869.2T patent/ES2550960T3/en active Active
2008-02-01 CA CA 2677122 patent/CA2677122C/en not_active Expired - Fee Related
2008-02-01 AU AU2008210293A patent/AU2008210293B2/en not_active Ceased
2008-02-01 JP JP2009548482A patent/JP5224478B2/en active Active
2008-02-01 US US12/024,947 patent/US8594785B2/en active Active
2008-02-01 EP EP08728869.2A patent/EP2114518B1/en active Active
WO1995000201A1 (en) 1993-06-23 1995-01-05 Medtronic, Inc. An apparatus for monitoring atrioventricular intervals
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Office Action dated Jun. 27, 2011 in European Application No. 08728869.2-2305, Applicant: Boston Scientific Neuromodulation Corporation, (3pages).
Office Action dated May 10, 2011 in Australian Application No. 2008210293, Applicant: Boston Scientific Neuromodulation Corporation, (2pages).
Office Action dated Nov. 5, 2010 in Australian Application No. 2008210293, Applicant: Boston Scientific Neuromodulation Corporation, (2pages).
Office Action drafted on May 2, 2012 for Japanese Patent Application No. 2009-548482, Applicant: Boston Scientific Neuromodulation Corporation, (3pages); with translations prepared by Nakamura & Partners (4pages).
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PCT Written Opinion of the International Search Authority for PCT/US2008/052851, Applicant: Boston Scientific Neuromodulation Corporation, Form PCT/ISA/237, dated Jun. 24, 2008 (5 pages).
CA2677122A1 (en) 2008-08-07
US20080188909A1 (en) 2008-08-07
ES2550960T3 (en) 2015-11-13
JP5224478B2 (en) 2013-07-03
JP2010517637A (en) 2010-05-27
EP2114518B1 (en) 2015-09-23
AU2008210293B2 (en) 2011-05-19
WO2008095185A1 (en) 2008-08-07
AU2008210293A1 (en) 2008-08-07
CA2677122C (en) 2014-12-09
EP2114518A1 (en) 2009-11-11
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BRADLEY, KERRY;REEL/FRAME:021406/0941