Source: http://www.google.com/patents/US20060111666?dq=6,424,354
Timestamp: 2015-03-31 00:44:16
Document Index: 479838126

Matched Legal Cases: ['art 1', 'art 10', 'art 1', 'art 1', 'art 1', 'art 10', 'art 10', 'art 10', 'art 10', 'art 10', 'art 10', 'art 1', 'art 10', 'art 10', 'art 10', 'art 1', 'art 10']

Patent US20060111666 - Auto-pen for a two-chamber ampoule - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsAn injection device for use with a two-chamber ampoule, wherein the device includes a front casing part with which the two-chamber ampoule can be associated, a rear casing part, a threaded drive accommodated by the rear casing part, a piston rod which, during a blending movement, is moved by the threaded...http://www.google.com/patents/US20060111666?utm_source=gb-gplus-sharePatent US20060111666 - Auto-pen for a two-chamber ampouleAdvanced Patent SearchPublication numberUS20060111666 A1Publication typeApplicationApplication numberUS 11/218,322Publication dateMay 25, 2006Filing dateSep 1, 2005Priority dateSep 2, 2004Also published asDE102004042581A1, US7815598Publication number11218322, 218322, US 2006/0111666 A1, US 2006/111666 A1, US 20060111666 A1, US 20060111666A1, US 2006111666 A1, US 2006111666A1, US-A1-20060111666, US-A1-2006111666, US2006/0111666A1, US2006/111666A1, US20060111666 A1, US20060111666A1, US2006111666 A1, US2006111666A1InventorsEdgar Hommann, Benjamin Scherer, Ian ThompsonOriginal AssigneeEdgar Hommann, Benjamin Scherer, Ian ThompsonExport CitationBiBTeX, EndNote, RefManReferenced by (6), Classifications (10), Legal Events (2) External Links: USPTO, USPTO Assignment, EspacenetAuto-pen for a two-chamber ampoule
US 20060111666 A1Abstract
An injection device for use with a two-chamber ampoule, wherein the device includes a front casing part with which the two-chamber ampoule can be associated, a rear casing part, a threaded drive accommodated by the rear casing part, a piston rod which, during a blending movement, is moved by the threaded drive toward a dispensing end of the device and slaves at least a closing piston of the two-chamber ampoule in the process, wherein a spring element presses the piston rod toward the dispensing end during a delivery movement. Images(4) Claims(18)
DETAILED DESCRIPTION The injection pen shown in FIG. 1 comprises a front casing part 1 and a rear casing part 10 which are screwed together by means of co-operating threads 26. The front casing part 1 contains a two-chamber ampoule 2. The two-chamber ampoule 2 comprises a bypass 3 on its wall and a facing surface with a closure 7 at its front end facing in the distal direction P. A closing piston 4 and a dividing piston 5 are located in the two-chamber ampoule 2 and are both located in a proximal arrangement with respect to the bypass 3. The two pistons 4, 5 abut the inner wall of the two-chamber ampoule 2, outside the bypass 3, forming a seal. A fluid product 8 is located in the space between the closing piston 4 and the dividing piston 5. A dry, mostly powdery substance 9, which together with the fluid product 8 forms a mixed product 8, 9, is located in the space between the closure 7 and the dividing piston 5. The two-chamber ampoule 2 is introduced into the front casing part 1 via its proximal end, to which end a groove 6 running in an axial direction A is contained in the front casing part 1 and creates a space for the bypass 3 of the two-chamber ampoule 2. The rear casing part 10 substantially contains the piston rod 11, spheres 12 acting as holding elements, a retainer 16, a threaded nut 21, a threaded rod 19 and a coil spring 14. A rotating knob 22 is attached to the proximal end of the injection device and is connected to the threaded rod 19 by two elements 23 co-operating in a positive lock. Locking elements 24 formed on the rotating knob 22 grip behind a collar which faces radially inwards and is formed on the proximal end of the rear casing part 10, such that the rotating knob 22 cannot be moved axially relative to the rear casing part 10, but exhibits a rotational degree of freedom. A threaded drive 19/21 is formed by the threaded nut 21 via the outer thread 20 attached to the threaded rod 19. The threaded nut 21 is rotationally fixed in the rear casing part 10, but can be moved axially. The threaded nut 21 is connected to a retainer 16 which can also only be moved in the axial direction A in the rear casing part 10. The threaded nut 21 and the retainer 16 are fixedly connected to each other, such that it is only necessary to rotationally fix one of the two components 16, 21 in order to obtain a rotational block. A radial heel 27 is attached to the distal end of the retainer 16 and simultaneously serves as an axial guide for the piston rod 11. Guides 30 which run in an approximately radial direction are attached in the area of the radial heel 27 for each of the spheres 12 serving as a holding element. These guides 30 are preferably bores having a circular cross-section and thus corresponding to the cross-section of the spheres 12. An annularly circumferential groove 13, with which the spheres 12 engage, is located on the piston rod 11 and approximately exhibits the contour of the spheres 12. The outer casing part 10 guides the retainer 16 axially and simultaneously forms a radial stopper for the spheres 12, such that they cannot be pressed out of the groove 13. A radial collar 28 is located at the proximal end of the piston rod 11 and is also guided by the peripheral surface of the retainer 16. Before a delivery process, there is a distance d1 between the radial collar 28 and the radial heel 27. The coil spring 14 surrounding the threaded rod 19 is located between the radial collar 28 and the threaded nut 21. The coil spring 14 is biased and exerts a force in the distal direction on the piston rod 11. Initially, however, the coil spring 14 cannot move the piston rod 11 axially, since the piston rod 11 is blocked by the spheres 12. The blending process and/or blending movement is caused by rotating the rotating knob 22. The rotation transferred onto the threaded rod 19 is converted via the thread pitch and via the rotationally fixed threaded nut 21 into an axial movement which is transferred via the retainer 16 and the holding elements and/or spheres 12 onto the piston rod 11. The retainer 16, the piston rod 11, the spheres 12, the threaded nut 21 and the coil spring 14 are thus moved towards the distal end of the injection device, without the coil spring 14 being relaxed. The distance d2, formed by facing sides of the proximal end of the front casing part 1 and the retainer 16, decreases with the number of rotations of the rotating knob 22. Moving the piston rod 11 in the distal direction P shifts the closing piston 4 in the distal direction P in the two-chamber ampoule 2. Due to the incompressibility of the fluid product 8, the dividing piston 5 is likewise moved in the distal direction P until it has completely reached the area of the bypass 3. Since the dividing piston 5 then no longer forms a seal, the fluid product 8 can flow via the bypass 3 past the dividing piston 5 into the front chamber of the two-chamber ampoule 2 and thus mix with the product 9. The blending process is complete when the closing piston 4 abuts the dividing piston 5 and has thus displaced almost the entire fluid product 8 between them. At the end of the blending process, the spheres 12 are simultaneously located axially in the area of blocking elements 18 connected to a triggering sleeve 15 which at least partially encloses the rear casing part 10. The surfaces 29 of the blocking elements 18, facing radially with respect to the longitudinal axis A, have approximately the same radial distance from the longitudinal axis A as the inner wall of the rear casing part 10. In this way, the surfaces 29 still press the spheres 12 into the groove 13 of the piston rod 11. The administering process is triggered by the axial movement of the triggering sleeve 15 in the distal direction P. The windows 17 contained in the rear casing part 10 allow the axial movement of the triggering sleeve 15. The axial force which is exerted by the coil spring 14 on the piston rod 11 presses the spheres 12 radially outwards into the windows 17, since the groove 13 is shaped such that, due to the axial force on the piston rod 11, at least a force component acting radially outwards acts on the spheres 12. Once the spheres 12 have entered the windows 17, the piston rod 11 is released, such that it is moved by the biased coil spring 14 relative to the retainer 16 in the distal direction P. The piston rod 11 then presses the two pistons 4, 5 in the distal direction P and thus delivers the mixed product 8, 9. If, at the start of the delivery process, the distance from the dividing piston 5 to the distal facing surface of the two-chamber ampoule 2 is larger than the distance d1, the piston rod 11 merely travels the path d1 within the scope of the delivery movement. If the distance between the dividing piston 5 and the distal facing side of the two-chamber ampoule 2 is smaller than the distance d1, then the mixed product 8, 9 is completely delivered from the two-chamber ampoule 2 without the path d1 having been completely traveled. During the delivery process, the spheres 12 are located in the windows 17, wherein the triggering sleeve 15 prevents the spheres 12 from falling out of the windows 17. At this time, the triggering sleeve 15 cannot be moved back to its original position, since the spheres 12 remain pressed into the windows 17 by the peripheral surface of the piston rod 11. In order to blend and administer the products of a two-chamber ampoule 2 again, the injection device has to be returned to its original position. To this end, the piston rod 11 is pressed in the proximal direction D. As soon as the groove 13 reaches the axial area of the spheres 12, the spheres 12 are pressed back into the groove 13 due to the spring 25 which exerts an axial force on the triggering sleeve 15 and thus exerts at least a portion of the force, facing radially with respect to the longitudinal axis A, on each of the spheres 12. The triggering sleeve 15 is snapped back into its original position by the blocking elements 18 due to the elasticity force of the spring 25. The surfaces 29 then again hold the spheres 12 firmly in the groove 13, such that the piston rod 11 is prevented from moving axially relative to the retainer 16. The mechanism, consisting of the retainer 16, the piston rod 11, the spheres 12, the threaded nut 21 and the coil spring 14, is moved back to its original position by rotating the rotating knob 22 back in a rotating direction counter to the blending movement. The front casing part 1 can then be fitted with a new two-chamber ampoule 2 and screwed onto the rear casing part 10 by the thread connection 26. The injection device is then once again ready for a new blending/delivery of the products in/from the two-chamber ampoule 2. Embodiments of the present invention, including preferred embodiments, have been presented for the purpose of illustration and description. They are not intended to be exhaustive or to limit the invention to the precise forms or steps disclosed. Obvious modifications or variations are possible in light of the above teachings. The embodiments were chosen and described to provide the best illustration of the principals of the invention and its practical application, and to enable one of ordinary skill in the art to utilize the invention in various embodiments and with various modifications as are suited to the particular use contemplated. All such modifications and variations are within the scope of the invention as determined by the appended claims when interpreted in accordance with the breadth they are fairly, legally, and equitably entitled. Referenced byCiting PatentFiling datePublication dateApplicantTitleUS8167834 *May 10, 2007May 1, 2012Owen Mumford LimitedInjection deviceUS8486006 *Sep 18, 2009Jul 16, 2013Becton, Dickinson And CompanyMedical injector with button activationUS8486007Mar 29, 2012Jul 16, 2013Owen Mumford LimitedInjection deviceUS8834449Feb 28, 2012Sep 16, 2014Ikomed Technologies, Inc.Mixing syringeUS20110213299 *Sep 18, 2009Sep 1, 2011Becton, Dickinson And CompanyMedical injector with button activationWO2012010832A1 *Jul 19, 2011Jan 26, 2012Future Injection Technologies LimitedInjection device* Cited by examinerClassifications U.S. Classification604/89, 604/191, 604/134International ClassificationA61M5/20, A61M37/00, A61M5/00Cooperative ClassificationA61M5/2033, A61M5/2448, A61M5/2066European ClassificationA61M5/20MLegal EventsDateCodeEventDescriptionApr 14, 2014FPAYFee paymentYear of fee payment: 4Nov 16, 2005ASAssignmentOwner name: TECPHARMA LICENSING AG, SWITZERLANDFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:HOMMANN, EDGAR;SCHERER, BENJAMIN;THOMPSON, IAN M.;REEL/FRAME:017229/0553;SIGNING DATES FROM 20051013 TO 20051019Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:HOMMANN, EDGAR;SCHERER, BENJAMIN;THOMPSON, IAN M.;SIGNING DATES FROM 20051013 TO 20051019;REEL/FRAME:017229/0553RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services