Source: http://www.science.gov/topicpages/a/action+program+major.html
Timestamp: 2016-10-25 01:32:12
Document Index: 127768696

Matched Legal Cases: ['§ 313', '§ 313', '§ 99', '§ 3052', '§ 3052', 'art 3015', '§ 23', '§ 23', 'art 3015', 'arts 271']

Sample records for action program major
Major Work Program Parent Guide.
This guide is designed to help parents and other interested persons understand the nature and needs of gifted children, to provide ideas and activities that will nurture gifted children, and to explain the components of the Major Work Program, which is the gifted education program of the Cleveland (Ohio) Public School District. The guide outlines…
Applicable or Relevant and Appropriate Requirements (ARARs) for Remedial Action at the Oak Ridge Reservation: A compendium of major environmental laws. Environmental Restoration Program
Etnier, E.L.; McDonald, E.P.; Houlberg, L.M.
Section 121 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980 specifies that remedial actions for cleanup of hazardous substances must comply with applicable or relevant and appropriate requirements (ARARS) or standards under federal and state environmental laws. The US Department of Energy (DOE) Oak Ridge Reservation (ORR) was placed on the National Priorities List by the US Environmental Protection Agency (EPA) on November 21, 1989, effective December 21, 1989. As a result of this listing, DOE, EPA, and the Tennessee Department of Environment and Conservation have signed a Federal Facility Agreement (FFA) for the environmental restoration of the ORR. Section XXI(F) of the FFA calls for the preparation of a draft listing of all ARARs as mandated by CERCLA {section}121. This report supplies a preliminary list of available federal and state ARARs that might be considered for remedial response at the ORR. A description of the terms ``applicable`` and ``relevant and appropriate`` is provided, as well as definitions of chemical-, location-, and action-specific ARARS. ARARs promulgated by the federal government and by the state of Tennessee are listed in tables. In addition, the major provisions of the Resource Conservation and Recovery Act, the Safe Drinking Water Act, the Clean Water Act, the Clean Air and other acts, as they apply to hazardous waste cleanup, are discussed. In the absence of ARARS, CERCLA {section}121 provides for the use of nonpromulgated federal criteria, guidelines, and advisories in evaluating the human risk associated with remedial action alternatives. Such nonpromulgated standards are classified as ``to-be-considered`` (TBC) guidance. A ion of available guidance is given; summary tables fist the available federal standards and guidance information. In addition, the substantive contents of the DOE orders as they apply to remediation of radioactively contaminated sites are discussed as TBC guidance.
14 CFR 313.4 - Major regulatory actions.
... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Major regulatory actions. 313.4 Section 313.4 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL REGULATIONS IMPLEMENTATION OF THE ENERGY POLICY AND CONSERVATION ACT § 313.4 Major...
... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Major regulatory actions. 313.4 Section 313.4 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL REGULATIONS IMPLEMENTATION OF THE ENERGY POLICY AND CONSERVATION ACT § 313.4 Major...
... document in the working papers the risk analysis process used in determining major programs. (h) Auditor's... Auditors § 99.520 Major program determination. (a) General. The auditor shall use a risk-based approach to determine which Federal programs are major programs. This risk-based approach shall include consideration...
Management of major system programs and projects. Handbook
This Handbook establishes the detailed policies and processes for implementing NMI 7120.4, 'Management of Major System Programs and Projects'. It constitutes a comprehensive source of the specific policies and processes governing management of major development programs/projects and is intended as a resource to the entire program/project management (PPM) community.
Major Causes of Organizational Conflict: Diagnosis for Action. Working Paper.
Six major causes of organizational conflict (individual stress, role conflict, power struggles, differentiation, interdependence, and external pressures) are delineated; implications for managing these conflicts using collaboration, bargaining, and power plays are pointed out; a conflict management paradigm pointing out which mode of conflict…
The Unified Core: A "Major" Learning Community Model in Action
Powell, Gwynn M.; Johnson, Corey W.; James, J. Joy; Dunlap, Rudy
The Unified Core is an innovative approach to higher education that blends content through linked courses within a major to create a community of learners. This article offers the theoretical background for the approach, describes the implementation, and offers suggestions to educators who would like to design their own version of this innovative…
Grosse, Christine Uber; Lubell, Dawna
7 CFR 3052.520 - Major program determination.
... 7 Agriculture 15 2011-01-01 2011-01-01 false Major program determination. 3052.520 Section 3052.520 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditors § 3052.520 Major program...
... auditor is not expected to perform risk assessments on relatively small Federal programs. Therefore, the auditor is only required to perform risk assessments on Type B programs that exceed the larger of: (i... Auditors § 3052.520 Major program determination. (a) General. The auditor shall use a risk-based...
Fishman, Sigal; Muzumdar, Radhika H; Atzmon, Gil; Ma, Xiaohui; Yang, Xiaoman; Einstein, Francine H; Barzilai, Nir
Impairment of both insulin and leptin action has been implicated in the pathogenesis of nonalcoholic fatty liver disease. By assessing hepatic triglyceride (TG) stores in response to modulation of leptin action (by leptin infusion), we attempted to determine whether leptin has the major role in hepatic TG accumulation. TG were markedly decreased (by 63%, P<0.05) in young animals treated with leptin. However, this was also associated with improvement in hepatic insulin action (2-fold decrease in HGP during clamp, P<0.05). These effects on hepatic TG stores and insulin action were abolished in old rats who demonstrate leptin resistance. Since these experiments could not discern the role of leptin from the role of hepatic insulin action on hepatic TG stores, we further examined the effect of improvement of hepatic insulin action by visceral fat removal (VF-). Enhancement of hepatic insulin action in old VF-rats was associated with reduced hepatic TG stores (by 64% P<0.01). Because this manipulation may have induced an improvement in leptin action as well, we studied VF removal in a genetically leptin-resistant model (Zucker Diabetic Fatty rats, ZDF). Only in this mode was exclusive improvement of hepatic insulin action by VF removal not associated with reduced hepatic TG stores, suggesting that improved hepatic insulin action is not necessary for modulation of hepatic TG stores. By dissociating action of leptin from that of insulin, we suggest that the failure of leptin action is the major physiological mechanism for hepatic steatosis. PMID:17099068
.... (g) Documentation of risk. The auditor shall document in the working papers the risk analysis process... determination. (a) General. The auditor shall use a risk-based approach to determine which Federal programs are major programs. This risk-based approach shall include consideration of: Current and prior...
2 CFR 200.518 - Major program determination.
... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Major program determination. 200.518 Section 200.518 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GUIDANCE Reserved UNIFORM ADMINISTRATIVE REQUIREMENTS, COST...
... 49 Transportation 6 2012-10-01 2012-10-01 false Guidelines for identifying major actions significantly affecting the environment. 520.5 Section 520.5 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURES FOR CONSIDERING ENVIRONMENTAL...
... 49 Transportation 6 2013-10-01 2013-10-01 false Guidelines for identifying major actions significantly affecting the environment. 520.5 Section 520.5 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURES FOR CONSIDERING ENVIRONMENTAL...
... 49 Transportation 6 2011-10-01 2011-10-01 false Guidelines for identifying major actions significantly affecting the environment. 520.5 Section 520.5 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURES FOR CONSIDERING ENVIRONMENTAL...
22 CFR 161.12 - Environmental effects abroad of major departmental actions.
... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Environmental effects abroad of major departmental actions. 161.12 Section 161.12 Foreign Relations DEPARTMENT OF STATE ENVIRONMENTAL PROTECTION REGULATIONS FOR IMPLEMENTATION OF THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA) Coordination of...
... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Environmental effects abroad of major departmental actions. 161.12 Section 161.12 Foreign Relations DEPARTMENT OF STATE ENVIRONMENTAL PROTECTION REGULATIONS FOR IMPLEMENTATION OF THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA) Coordination of...
Chronology: MSFC Space Station program, 1982 - present. Major events
Whalen, Jessie E. (Compiler); Mckinley, Sarah L. (Compiler); Gates, Thomas G. (Compiler)
Heneman, Herbert G., III; Worth, Robin; Arrigoni, Jessica; Kimball, Steven M.; Milanowski, Anthony
Matte, Christine; Casgrain, Pierre-André; Séguin, Olivier; Moradin, Neda; Hong, Wan Jin; Descoteaux, Albert
The protozoan Leishmania parasitizes macrophages and evades the microbicidal consequences of phagocytosis through the inhibition of phagolysosome biogenesis. In this study, we investigated the impact of this parasite on LC3-associated phagocytosis, a non-canonical autophagic process that enhances phagosome maturation and functions. We show that whereas internalization of L. major promastigotes by macrophages promoted LC3 lipidation, recruitment of LC3 to phagosomes was inhibited through the action of the parasite surface metalloprotease GP63. Reactive oxygen species generated by the NOX2 NADPH oxidase are necessary for LC3-associated phagocytosis. We found that L. major promastigotes prevented, in a GP63-dependent manner, the recruitment of NOX2 to phagosomes through a mechanism that does not involve NOX2 cleavage. Moreover, we found that the SNARE protein VAMP8, which regulates phagosomal assembly of the NADPH oxidase NOX2, was down-modulated by GP63. In the absence of VAMP8, recruitment of LC3 to phagosomes containing GP63-deficient parasites was inhibited, indicating that VAMP8 is involved in the phagosomal recruitment of LC3. These findings reveal a role for VAMP8 in LC3-associated phagocytosis and highlight a novel mechanism exploited by L. major promastigotes to interfere with the host antimicrobial machinery. PMID:27280768
76 FR 51274 - Supplemental Nutrition Assistance Program: Major System Failures
... Register FR Federal Fiscal Year FY Food and Nutrition Act of 2008 the Act Food and Nutrition Service FNS... final rule in 7 CFR part 3015, Subpart V and related document published June 24, 1983 (48 FR 29114 for SNP; 48 FR 29115 for FSP), this Program is excluded from the scope of E.O. 12372, which...
Eisenhower Program for Math and Science Gets Major Boost.
A training program that allows scientists and educators to experiment with new ways to improve student performance in science and mathematics is described. Scientists and educators are encouraged to work together to develop projects for in-service education and projects that can be worked on by students in the laboratory. (KR)
Stoloff, Michael L.; Good, Megan Rodgers; Smith, Kristen L.; Brewster, JoAnne
Hosek, Susan D.; Cox, Amy G.; Ghosh-Dastidar, Bonnie; Kofner, Aaron; Ramphal, Nishal; Scott, Jon; Berry, Sandra H.
Using the Boston Consulting Group Matrix To Analyze College Programs: Should that New Major Be Approved?
Green, Mark T.; Odom, Lamar; Alexander, Jacquelyn; Hudspeth, Elizabeth; Hudsepth, Gregory
Describes potential use of Boston Consulting Group Matrix to evaluate proposed new college and university programs or majors. The product evaluation matrix consisted of two major variables: product growth rate and market share. Provides an example of the matrix. (PKP)
Oppenhauser, Gotthard
Who Controls Major Federal Programs for Children & Families: Rube Goldberg Revisited. Special Report #3.
This report provides a detailed examination of the various federal programs for children and families and outlines ways in which the United States Congress and Executive Branch could make these programs work better. Intricate and often overlapping goals and actions are typical of the Congressional committees and Executive Branch departments that…
17 CFR 23.600 - Risk Management Program for swap dealers and major swap participants.
... pricing (excluding price verification for risk management purposes), trading, sales, marketing... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Risk Management Program for... Major Swap Participants § 23.600 Risk Management Program for swap dealers and major swap...
... pricing (excluding price verification for risk management purposes), trading, sales, marketing... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Risk Management Program for... Major Swap Participants § 23.600 Risk Management Program for swap dealers and major swap...
Developing an Effective Major Gift Program: From Managing Staff to Soliciting Gifts.
Muir, Roy, Ed.; May, Jerry, Ed.
This publication contains 15 papers concerned with the establishment at colleges and universities of new major gift programs or the improvement of existing programs. The papers, all by development professionals in higher education, are as follows: (1) "An Introduction to the Major Gift Process" (Jon Cosovich); (2) "Strategic Management of a Major…
Major U.S. Supreme Court Civil Rights/Affirmative Action Decisions, January-June 1989.
Illustrates how the Supreme Court has been divided in its 1989 decisions on affirmative action. Reviews the following cases: City of Richmond v. J.A. Croson Co.; Price Waterhouse v. Hopkins; Wards Cove Packing Company, Inc. v. Antonio; Martin v. Wilks; Lorance v. AT&T Technologies, Inc.; Patterson v. McLean Credit Union; and Jett v. Dallas…
... Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... significantly affecting the quality of the human environment,” as used in this part, shall be construed with a... actions should ordinarily be considered as significantly affecting the quality of the human...
Toward a Communicative Program for English Majors in Japan: The Case at Sugiyama.
Atkins, Ronda Kay; Tanaka, Sachiko Oda
Describes curricular changes in a private Japanese university's English department, and explores the curricula typical of such programs. The new program's three major features, including a freshman English program, a content study, and graduation papers and theses are highlighted. (12 references) (Author/CB)
Major Management Challenges and Program Risks, Department of Education. Performance and Accountability Series.
This report addresses the major performance and management challenges that have limited the effectiveness of the Department of Education in carrying out its mission. The booklet addresses corrective actions that Education has taken or initiated on these challenges--including a number of management initiatives to improve controls over the…
Sketches of Local Action Programs for School Environmental Education 12/73 to 6/74.
Project KARE, Blue Bell, PA.
Twenty-two elementary and secondary schools from throughout the five-county Southeastern Pennsylvania region were selected by Project KARE (Knowledgeable Action to Restore our Environment) to receive grants for Local Action Programs (LAP) of environmental education during 1973-1974. This guide reviews these twenty-two programs including the…
Zakocs, Ronda; Hill, Jessica A.; Brown, Pamela; Wheaton, Jocelyn; Freire, Kimberley E.
Although health education programs may benefit from quality improvement methods, scant resources exist to help practitioners apply these methods for program improvement. The purpose of this article is to describe the Data-to-Action framework, a process that guides practitioners through rapid-feedback cycles in order to generate actionable data to…
In and of the City: Theory of Action and the NYU Partnership School Program
McDonald, Joseph P.; Domingo, Myrrh; Jeffery, Jill V.; Pietanza, Rosa Riccio; Pignatosi, Frank
This article explores the theory of action underlying New York University&apos;s (NYU&apos;s) Partnership Schools Program--explaining in the process what a theory of action is, and how it can be constructed for other innovations in other contexts. NYU&apos;s Partnership Program involves 23 schools, K-12, spanning several of New York City&apos;s…
Helping Migrant and Seasonal Farm Worker Families. Annual Report 1971 [Migrant Action Program, Mason City, Iowa].
Migrant Action Program, Mason City, IA.
The objective of the Migrant Action Program (MAP) in Iowa is to assist the migrant and seasonal farm workers and their families. This 1971 annual report cntains a description of the program goals and activities, including the Manpower Project, children's programs, day care, vehicle purchase and use, the health program, and emergency food…
Niciu, Mark J.; Ionescu, Dawn F.; Mathews, Daniel C.; Richards, Erica M.; Zarate, Carlos A.
The etiopathogenesis and treatment of major mood disorders have historically focused on modulation of monoaminergic (serotonin, norepinephrine, dopamine) and amino acid [γ-aminobutyric acid (GABA), glutamate] receptors at the plasma membrane. Although the activation and inhibition of these receptors acutely alter local neurotransmitter levels, their neuropsychiatric effects are not immediately observed. This time lag implicates intracellular neuroplasticity as primary in the mechanism of action of antidepressants and mood stabilizers. The modulation of intracellular second messenger/signal transduction cascades affects neurotrophic pathways that are both necessary and sufficient for monoaminergic and amino acid–based treatments. In this review, we will discuss the evidence in support of intracellular mediators in the pathophysiology and treatment of preclinical models of despair and major depressive disorder (MDD). More specifically, we will focus on the following pathways: cAMP/PKA/CREB, neurotrophin-mediated (MAPK and others), p11, Wnt/Fz/Dvl/GSK3β, and NFκB/ΔFosB. We will also discuss recent discoveries with rapidly acting antidepressants, which activate the mammalian target of rapamycin (mTOR) and release of inhibition on local translation via elongation factor stimulation. Throughout this discourse, we will highlight potential intracellular targets for therapeutic intervention. Finally, future clinical implications are discussed. PMID:23462230
Teaching and Studying Social Issues: Major Programs and Approaches. Research in Curriculum and Instruction
"Teaching and Studying Social Issues: Major Programs and Approaches" focuses on many of the major innovations developed over the past 100 years by noted educators to assist students in the study and analysis of key social issues that impact their lives and society. This book complements earlier books that address other aspects of studying and…
Wu, Yong; Zhao, Weidong; Zhao, Jingbo; Zhang, Yuanfei; Qin, Weiping; Pan, Jiangping; Bauman, William A.; Blitzer, Robert D.; Cardozo, Christopher
Glucocorticoids are a well-recognized and common cause of muscle atrophy that can be prevented by testosterone. However, the molecular mechanisms underlying such protection have not been described. Thus, the global effects of testosterone on dexamethasone-induced changes in gene expression were evaluated in rat gastrocnemius muscle using DNA microarrays. Gene expression was analyzed after 7-d administration of dexamethasone, dexamethasone plus testosterone, or vehicle. Dexamethasone changed expression of 876 probe sets by at least 2-fold. Among these, 474 probe sets were changed by at least 2-fold in the opposite direction in the dexamethasone plus testosterone group (genes in opposition). Major biological themes represented by genes in opposition included IGF-I signaling, myogenesis and muscle development, and cell cycle progression. Testosterone completely prevented the 22-fold increase in expression of the mammalian target of rapamycin (mTOR) inhibitor regulated in development and DNA damage responses 1 (REDD1), and attenuated dexamethasone induced increased expression of eIF4E binding protein 1, Forkhead box O1, and the p85 regulatory subunit of the IGF-I receptor but prevented decreased expression of IRS-1. Testosterone attenuated increases in REDD1 protein in skeletal muscle and L6 myoblasts and prevented dephosphorylation of p70S6 kinase at the mTOR-dependent site Thr389 in L6 myoblast cells. Effects of testosterone on REDD1 mRNA levels occurred within 1 h, required the androgen receptor, were blocked by bicalutamide, and were due to inhibition of transcriptional activation of REDD1 by dexamethasone. These data suggest that testosterone blocks dexamethasone-induced changes in expression of REDD1 and other genes that collectively would otherwise down-regulate mTOR activity and hence also down-regulate protein synthesis. PMID:20032058
76 FR 24820 - Supplemental Nutrition Assistance Program: Review of Major Changes in Program Design and...
... rule in 7 CFR part 3015, Subpart V and related Notice (48 FR 29115), this Program is excluded from the..., or Phrase symbol Code of Federal Regulations CFR. Federal Register FR. Federal Fiscal Year FY. Food... Food and Nutrition Service 7 CFR Parts 271, 272, and 275 RIN 0584-AD86 Supplemental...
Chronology: MSFC Space Shuttle program development, assembly, and testing major events (1969 - April, 1981)
Listings of major events directly related to the Space Shuttle Program at Marshall Space Flight Center (MSFC) are presented. This information will provide the researcher with a means of following the chronological progression of the program. The products that the historians have prepared are intended to provide supportive research essential to the writing of formal narrative histories of Marshall's contributions to the Space Shuttle and Space Station.
Bush, J. C.