Source: http://www.google.com/patents/US8137965?ie=ISO-8859-1&dq=5,915,131
Timestamp: 2015-07-07 19:22:06
Document Index: 464034126

Matched Legal Cases: ['application No. 10012560', 'Application No. 2003273292', 'Application No. 2003273292', 'Application No. 2009240818', 'Application No. 2', 'Application No. 03755791', 'Application No. 12', 'Application No. 2003', 'Application No. 03755791']

Patent US8137965 - Methods and compositions for tissue regeneration - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsA kit is disclosed that includes a first component comprising alginate, wherein the first component is comprised in a first sterile vial, and a second component comprising cells comprising keratinocytes or fibroblasts, or mixtures thereof, that secrete one or more biologically active molecules selected...http://www.google.com/patents/US8137965?utm_source=gb-gplus-sharePatent US8137965 - Methods and compositions for tissue regenerationAdvanced Patent SearchPublication numberUS8137965 B2Publication typeGrantApplication numberUS 12/967,619Publication dateMar 20, 2012Filing dateDec 14, 2010Priority dateSep 6, 2002Also published asCA2497193A1, EP1545565A1, EP1545565A4, EP1545565B1, EP2311469A2, EP2311469A3, US7144729, US7449333, US7700351, US7879605, US8323638, US8679475, US20030165482, US20060121002, US20090232791, US20100068281, US20110083987, US20120134962, US20130052168, US20140377229, WO2004022077A1Publication number12967619, 967619, US 8137965 B2, US 8137965B2, US-B2-8137965, US8137965 B2, US8137965B2InventorsEric Rolland, Thomas Hunziker, Beatrice Mis, Christopher RinschOriginal AssigneeDfb Technology Holdings, LlcExport CitationBiBTeX, EndNote, RefManPatent Citations (44), Non-Patent Citations (38), Classifications (63), Legal Events (2) External Links: USPTO, USPTO Assignment, EspacenetMethods and compositions for tissue regeneration
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS4485096May 26, 1982Nov 27, 1984Massachusetts Institute Of TechnologyTissue-equivalent and method for preparation thereofUS4837379Jun 2, 1988Jun 6, 1989Organogenesis Inc.Fibrin-collagen tissue equivalents and methods for preparation thereofUS5261255Nov 8, 1991Nov 16, 1993Instacool Inc. Of North AmericaDevice for fractionating constituent components of a substance using cryoprecipitationUS5290552Mar 23, 1992Mar 1, 1994Matrix Pharmaceutical, Inc./Project HearSurgical adhesive materialUS5474770Mar 12, 1992Dec 12, 1995Centre Regional De Transfusion Sanguine De LilleBiological support for cell cultures constituted by plasma proteins coagulated by thrombin, its use in the preparation of keratocyte cultures, their recovery and their transport for therapeutic purposesUS5536656Feb 9, 1994Jul 16, 1996Organogenesis, Inc.Preparation of tissue equivalents by contraction of a collagen gel layered on a collagen gelUS5639654Jun 6, 1995Jun 17, 1997Centre International De Recherches DermatologiquesProcess for creating a skin substitute and the resulting skin substituteUS5855617Sep 12, 1996Jan 5, 1999Colorado State University Research FoundationTreated tissue for implantation and methods of treatment and useUS5863296Jun 5, 1995Jan 26, 1999Colorado State University Research FoundationTreated tissue for implantation and methods of treatment and useUS5891558Nov 21, 1996Apr 6, 1999Tissue Engineering, Inc.Biopolymer foams for use in tissue repair and reconstructionUS5902608Dec 31, 1996May 11, 1999University Of North Carolina At Chapel HillSurgical aids containing pharmaceutically acceptable fixed-dried human blood plateletsUS5948429Nov 16, 1995Sep 7, 1999Tissue Engineering, Inc.Methods for preparing biopolymer foamsUS5968546May 15, 1998Oct 19, 1999Baur; MarcusKeratinocyte culture from precursor cellsUS6010887Sep 14, 1994Jan 4, 2000Imperial Chemical Industries PlcRegulation of gene expressionUS6054122Jun 7, 1995Apr 25, 2000The American National Red CrossSupplemented and unsupplemented tissue sealants, methods of their production and useUS6231879Jul 31, 1997May 15, 2001Neurotech S.A.Biocompatible devices with foam scaffoldsUS6432710Oct 3, 2000Aug 13, 2002Isolagen Technologies, Inc.Compositions for regenerating tissue that has deteriorated, and methods for using such compositionsUS6479052Dec 2, 1999Nov 12, 2002Bristol-Myers Squibb CompanySpray delivery of cellsUS6503539Feb 26, 1999Jan 7, 2003Biora Bioex AbMatrix protein compositions for wound healingUS6548297Nov 9, 1995Apr 15, 2003Celadon Science, Inc.Sheets of cultured epithelial cells used for wound repair and their cryopreservationUS6673603Aug 30, 2001Jan 6, 2004Modex Therapeutiques, S.A.Cell paste comprising keratinocytes and fibroblastsUS6692738Jan 26, 2001Feb 17, 2004The General Hospital CorporationDelivery of therapeutic biologicals from implantable tissue matricesUS6720009May 28, 2002Apr 13, 2004Biora Bioex AbMatrix protein compositions for treating infectionUS6730313Jan 25, 2001May 4, 2004Edwards Lifesciences CorporationDelivery systems for periadventitial delivery for treatment of restenosis and anastomotic intimal hyperplasiaUS7144729 *Dec 19, 2002Dec 5, 2006Dfb Pharmaceuticals, Inc.Methods and compositions for tissue regenerationUS7449333 *Sep 5, 2003Nov 11, 2008Dfb Pharmaceuticals, Inc.Methods and compositions for tissue regenerationUS7700351 *Oct 21, 2008Apr 20, 2010Dfb Pharmaceuticals, Inc.Methods and compositions for tissue regenerationUS7879605 *Sep 18, 2009Feb 1, 2011Dfb Technology Holdings, LlcMethods and compositions for tissue regenerationUS20020048563Aug 30, 2001Apr 25, 2002Baetge E. EdwardMethods and compositions for tissue regenerationUS20030166274Nov 15, 2002Sep 4, 2003Hewitt Charles W.Three-dimensional matrix for producing living tissue equivalentsDE19949290A1Oct 12, 1999Apr 26, 2001Albrecht BettermannPartikul�res Konstrukt zur Verwendung in der TransplantationsmedizinEP0339607A2Apr 26, 1989Nov 2, 1989Samuel Dr. ItayComposition for repair of cartilage and bone and method for their preparation as skeletal tissue implantES2132027A1 Title not availableJP2000501299A Title not availableJP2001517431A Title not availableWO1997006835A1Aug 12, 1996Feb 27, 1997Smith & NephewCell culture productsWO1999015637A1Sep 15, 1998Apr 1, 1999Hadasit Medical Research & DevFibrin microbeads and uses thereofWO2000025838A1Nov 4, 1999May 11, 2000Baxter IntElement provided with a fibrin layer, preparation and use thereofWO2000032207A1Dec 2, 1999Jun 8, 2000Squibb Bristol Myers CoSpray delivery of cellsWO2001003750A1Jul 6, 2000Jan 18, 2001Advanced Tissue Sciences IncHuman naturally secreted extracellular matrix-coated deviceWO2001024842A2Oct 4, 2000Apr 12, 2001Abalos Coyle DeborahHybrid matrices and hybrid matrix mixturesWO2002017980A2Aug 31, 2001Mar 7, 2002Edward E BaetgeMethods and compositions for tissue regenerationWO2002072800A1Feb 28, 2002Sep 19, 2002Ct Investig Energeticas CiematArtificial dermis and production method thereforWO2002078721A1Apr 2, 2002Oct 10, 2002Bio Tissue Technologies AgTwo-constituent compositions for the in situ production of cell transplants that comprise fibroblasts and keratinocytes* Cited by examinerNon-Patent CitationsReference1Badiavas, et al., "Retrovirally Mediated Gene Transfer in a Skin Equivalent Model of Chronic Wounds", J. Dermatol. Sci., 13:56-62, 1996.2Cooper, et al., "Use of a Composite Skin Graft Composed of Cultured Human Keratinocytes and Fibroblasts and a Collagen-GAG Matrix to Cover Full-Thickness Wounds on Athynic Mice", Surgery, 109:198-207, 1991.3Currie, et al., "The Use of Fibrin Glue in Skin Grafts and Tissue-Engineered Skin Replacements: A Review", Plast. Reconstr. Surg., 108:1713-1726, 2001.4Database Prous Science Intergrity (Online), "Modex advances Alox through early-stage clinical testing," Database accession No. 323719, Aug. 7, 2002.5Database WPI, "Artificial skin production-comprises cell cultivation of keratinocytes on base of gel of human fibrin populated with human fibroblasts," Section Ch., Week 199940, Derwent Publications, Ltd., AN 1999-471189, 1999.6Davies, "Synthetic materials for covering burn wounds: progress towards perfection. Part I. Short term dressing materials," Burns Incl Therm Inj. 10:94-103, 1983.7Del Rio, I., "A Preclinical Model for the Analysis of Genetically Modified Human Skin In Vivo," Human Gene Therapy, 13:959-968, 2002.8Extended European Search Report, issued in European patent application No. 10012560.8, dated Mar. 9, 2011.9Falanga et al., "Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent," Archives of Dermatology, 134(3):293-300, 1998.10Hunt et al., In: Current Surgical Diagnosis & Treatment pp. 86-98, 1988.11Hunt et al., In:. The Surgical Wound, Dineen & Hildrick-Smith, eds., pp. 1-18, 1981.12Kannon and Garrett, "Moist wound healing with occlusive dressings. A clinical review," Dermatol. Surg., 21:583-590, 1995.13Kolodka et al., "Evidence for Keratinocyte Stem Cells in vitro: Long Tenn Engraftment and Persistence of Transgene Expression from Retrovirus-Transduced Kerationocytes," Proc. Nat!. Acad. Sci. USA. 95:4356-4361. 1998.14Kuroyanagi et al., "A Cultured Skin Substitute Composed of castsand Kerationocytes with a Collagen Matrix: Preliminary Results of Clinical Trials," Ann. Plait. Surg., 31:340-351, 1993.15Langdon et al., "Reconstitution of Structure and Cell Function in Human Skin Grafts Derived from Cryopreserved Allogeneic Dennis and Autologous Cultured Keratinocytes," J. Invest. Dermatol., 91:478-485 , 1988.16Maruguchi, et al., "A New Skin Equivalent: Kerationocytes Proliferated and Differentiated on Collagen Sponge Containing Fibroblasts," Plast. Reconstr. Surg., 93:537-546, 1994.17Office Communication, issued in Australian Patent Application No. 2003273292, dated Dec. 13, 2007.18Office Communication, issued in Australian Patent Application No. 2003273292, dated Jan. 30, 2009.19Office Communication, issued in Australian Patent Application No. 2009240818, mailed on Nov. 29, 2011.20Office Communication, issued in Canadian Patent Application No. 2,497,193, dated Dec. 31. 2010.21Office Communication, issued in European Patent Application No. 03755791.5, dated Jul. 9, 2008.22Office Communication, issued in European Patent Application No. 12/967,619, dated Jan. 10, 2011.23Office Communication, issued in Japanese Patent Application No. 2003-157362, dated Oct. 15, 2009. (English Translation).24Office Communication, issued in U.S. Appl. No. 10/324,527, dated Apr. 13, 2005.25Office Communication, issued in U.S. Appl. No. 10/324,527, dated Apr. 14, 2006.26Office Communication, issued in U.S. Appl. No. 10/324,527, dated Jul. 22, 2005.27Office Communication, issued in U.S. Appl. No. 10/526,853, dated Jan. 8, 2008.28Office Communication, issued in U.S. Appl. No. 10/526,853. dated Aug. 21, 2008.29Office Communication, issued in U.S. Appl. No. 12/255,481, dated Jun. 18, 2009,30Office Communication, issued in U.S. Appl. No. 12/562,767, dated Mar. 17, 2010.31PCT International Search Report issued in International Application No. PCT/US01/27104, dated Apr. 8, 2002.32PCT International Search Report issued in International Application No. PCT/US03/27888, dated Dec. 4, 2003.33Richey et al. "Topical growth factors and wound contraction in the rat: Part I. Literature review and definition of the rat model," Annals of Plastic Surgery 23(2): 159-165, 1989.34Riley, "Wound healing," Am. Pam. Physician 24: 107-113, 1981.35Singer et al., "Cutaneous Wound Healing," New England Journal of Medicine, 341:738-746, 1999.36Sugihara, et al., "Effects of Fat Cells on Keratinocytes and Fibroblasts in a Reconstructed Rat Skin Model Using Collagen Gel Matrix Culture," British J. Dennatol., 144:244-253, 2001.37Supplementary European Search Report issued in European Patent Application No. 03755791.5, dated Mar. 28, 2008.38Winter, "Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig," Nature, 193: 293.294, 1962.Classifications U.S. Classification435/325, 435/366, 435/371International ClassificationA61K38/18, A61F13/00, A61K35/36, C12N5/071, A61K38/19, A61K38/20, A61L31/00, C12N5/00, A61K35/12, C12N5/07, A61L15/44, C12N5/10, C12N5/22, A61K48/00, A61L27/00, A61L27/38, C12N5/077, A61L26/00, A61L15/40Cooperative ClassificationA61L15/40, A61K35/33, A61K35/36, A61K47/10, A61K9/0014, A61L27/3813, A61L27/3886, A61K41/0023, C12N2502/094, C12N2502/1323, C12N5/0656, A61K38/4833, A61K38/19, A61L27/3633, A61K9/19, A61K38/363, C12N2510/00, C12N5/0698, C12N2510/04, A61L27/3804, A61L26/0057, A61K9/10, A61K38/18, A61K48/00, A61L27/3616European ClassificationA61K35/12, A61K38/20, A61K35/36, A61K38/18, A61K38/19A, C12N5/06B13F, A61L27/36B14, A61L15/40, A61L27/38F, A61L26/00F, C12N5/06T2, A61K38/19B, A61L27/38B4, A61L27/38B, A61K38/48K5, A61K38/36ALegal EventsDateCodeEventDescriptionDec 17, 2012ASAssignmentOwner name: HEALTHPOINT INTERNATIONAL, LLC, TEXASFree format text: CHANGE OF NAME;ASSIGNORS:DFB TECHNOLOGY HOLDINGS, LLC;HEALTHPOINT HOLDINGS, LLC;REEL/FRAME:029481/0540Effective date: 20111229Mar 14, 2013ASAssignmentOwner name: SMITH & NEPHEW, INC., TENNESSEEFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:HEALTHPOINT INTERNATIONAL, LLC;REEL/FRAME:029994/0633Effective date: 20121221RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services