Source: http://www.google.com/patents/US5716379?dq=7,444,563
Timestamp: 2016-12-03 20:22:34
Document Index: 525264436

Matched Legal Cases: ['art.\n1', 'art 2', 'art 2', 'art 2', 'art 2', 'art 2']

Patent US5716379 - Cardiac assist device having muscle augmentation prior to defibrillation - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsA cardiac assist device having muscle augmentation during confirmed arrhythmia. In particular the present invention operates, in a first embodiment, to sense a cardiac event, next it determines whether the cardiac event is a cardiac arrhythmia, if the event is not a cardiac arrhythmia the devices delivers...http://www.google.com/patents/US5716379?utm_source=gb-gplus-sharePatent US5716379 - Cardiac assist device having muscle augmentation prior to defibrillationAdvanced Patent SearchTry the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents.Publication numberUS5716379 APublication typeGrantApplication numberUS 08/516,419Publication dateFeb 10, 1998Filing dateAug 17, 1995Priority dateAug 17, 1995Fee statusLapsedAlso published asCA2183304A1, EP0759308A2, EP0759308A3Publication number08516419, 516419, US 5716379 A, US 5716379A, US-A-5716379, US5716379 A, US5716379AInventorsIvan Bourgeois, Pierre A. GrandjeanOriginal AssigneeMedtronic, Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (13), Non-Patent Citations (12), Referenced by (19), Classifications (11), Legal Events (4) External Links: USPTO, USPTO Assignment, EspacenetCardiac assist device having muscle augmentation prior to defibrillation
US 5716379 AAbstract
A cardiac assist device having muscle augmentation during confirmed arrhythmia. In particular the present invention operates, in a first embodiment, to sense a cardiac event, next it determines whether the cardiac event is a cardiac arrhythmia, if the event is not a cardiac arrhythmia the devices delivers stimulation to a skeletal muscle grafted about a heart, but if the event is a cardiac arrhythmia the device inhibits delivery of skeletal muscle stimulation and once the arrhythmia is confirmed, then delivers therapeutic stimulation to the heart. In a second embodiment the present invention operates to re-initiate skeletal muscle stimulation once the arrhythmia is confirmed but prior to the delivery of the therapeutic stimulation to the heart.
1. An apparatus for stimulating a skeletal muscle grafted about a heart, detecting cardiac events and delivering therapeutic stimulation to the heart comprising:means for sensing a cardiac event; means for classifying the cardiac event as a normal sinus rhythm or as a cardiac fibrillation; means for delivering a normal sinus rhythm skeletal muscle pulse train to a skeletal muscle grafted about a heart upon the classification of a normal sinus rhythm, the normal sinus rhythm skeletal muscle pulse train having a first amplitude; means for delivering a defibrillation therapy upon the classification of a cardiac fibrillation, the defibrillation therapy comprising a defibrillation skeletal muscle pulse train and a defibrillation shock, the defibrillation skeletal muscle pulse train delivered upon the detection of a cardiac fibrillation, the defibrillation skeletal muscle pulse train having a second amplitude, the second amplitude being greater than the normal sinus rhythm skeletal muscle pulse train amplitude, the defibrillation shock delivered a first amount after defibrillation skeletal muscle pulse train; whereby the defibrillation skeletal muscle pulse train causes the heart to achieve a systolic position. 2. The apparatus of claim 1 wherein the normal sinus rhythm skeletal muscle pulse train has a first interpulse interval, the defibrillation skeletal muscle pulse train has a second interpulse interval, the first interpulse interval greater than the second interpulse interval.
The present invention generally relates to cardiac assist systems, including cardiomyoplasty, for the treatment of patients needing augmented cardiac output. More specifically, the present invention relates to a cardiac assist system which provides muscle augmentation prior to the delivery of a defibrillation therapy.
FIG. 1 illustrates an example of a system 1 for performing both long-term stimulation of skeletal muscles for cardiac assistance using systolic augmentation as well as direct electrical stimulation of a heart 2. As seen, skeletal muscle graft 3 is positioned about the heart 2. In the preferred embodiment the latissimus dorsi muscle is used for the skeletal muscle graft, as is well known in the art. The longitudinal fibers of the muscle graft 3 are oriented generally perpendicular to the longitudinal axes of the right ventricle 4, left ventricle 5 and interventricular septum 10 of the heart. Muscle graft 3 is positioned in this manner so that when it is stimulated, muscle graft 3 compresses ventricles 4, 5 and particularly left ventricle 5, to thereby improve the force of right and left ventricular contraction. In such a manner the overall hemodynamic output of heart 2 is increased.
Muscle Stimulation Prior to Delivery of Defibrillation Pulse
FIG. 6 is a timing diagram showing the relationship between muscle stimulation and cardiac events of an alternate embodiment. In particular, in an alternate embodiment, if synchronization is unsuccessful, then the device delivers an asynchronous muscle stimulation burst 322 immediately prior to defibrillation discharge 214, as best seen in FIG. 6. Muscle stimulation burst 322 is intended to cause the heart to be squeezed by the skeletal muscle graft and achieve roughly a systolic position when defibrillation discharge 214 is delivered. Because the volume of the heart in such a position is decreased, the defibrillation threshold is likewise decreased. In an alternate embodiment, burst 322 has a higher repetition rate, greater amplitude, interpulse interval and train duration than muscle stimulation burst 201. Of course, in alternate embodiments burst 322 may have any of the following different as compared to muscle stimulation burst 201: higher repetition rate, amplitude, pulse width, interpulse interval or train duration.
Muscle Stimulation Featuring Muscle Catch
FIG. 7 depicts an alternate muscle stimulation burst which may be used with the present system. These muscle stimulation bursts may be used at any suitable time within the present system, and are not limited to only use prior to delivery of the defibrillation therapy. As seen muscle stimulation burst 300 occurs after QRS 303 in the amount of a synchronization delay 305. In the preferred embodiment synchronization delay 305 is programmable and is undertaken in order to synchronize the muscle stimulation burst 300 with the ventricular contraction. Muscle stimulation burst 300 has essentially two section, first section 301 and second section 302, often referred to as "muscle catch" and "muscle pulse train" respectively. As seen, first section 301 has a smaller interpulse interval 304 within the burst, i.e. a higher frequency. In comparison second section 302 has a relatively larger interpulse interval 304 within the burst, i.e. a relatively smaller frequency. The higher frequency first section 301 increases the velocity and force of the skeletal muscle graft contraction. In the preferred embodiment interpulse interval 304 and number of pulses in the catch may be selected by the physician. The pulse waveform, amplitude 308 and width of the muscle catch are the same for the remainder of the burst.
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Chiu.* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS5984857 *Aug 29, 1994Nov 16, 1999Thoratec Laboratories CorporationStep-down skeletal muscle energy conversion systemUS6091989 *Sep 14, 1998Jul 18, 2000Swerdlow; Charles D.Method and apparatus for reduction of pain from electric shock therapiesUS7118567Apr 30, 2004Oct 10, 2006Medtronic Vascular, Inc.Method for treating vulnerable plaqueUS7494459Jun 26, 2003Feb 24, 2009Biophan Technologies, Inc.Sensor-equipped and algorithm-controlled direct mechanical ventricular assist deviceUS7931646Aug 31, 2006Apr 26, 2011Medtronic Vascular, Inc.Method for treating vulnerable plaqueUS8401637Nov 22, 2005Mar 19, 2013Galvani, Ltd.Medium voltage therapy applications in treating cardiac arrestUS8483822Jul 2, 2010Jul 9, 2013Galvani, Ltd.Adaptive medium voltage therapy for cardiac arrhythmiasUS9125655Jul 18, 2011Sep 8, 2015California Institute Of TechnologyCorrection and optimization of wave reflection in blood vesselsUS9144684Jul 22, 2014Sep 29, 2015Galvani, Ltd.Medium voltage therapy applied as a test of a physiologic stateUS9421391Jun 1, 2015Aug 23, 2016Galvani, Ltd.Coordinated medium voltage therapy for improving effectiveness of defibrillation therapyUS20040220620 *Apr 30, 2004Nov 4, 2004Donovan Maura G.Method for treating vulnerable plaqueUS20040267086 *Jun 26, 2003Dec 30, 2004Anstadt Mark P.Sensor-equipped and algorithm-controlled direct mechanical ventricular assist deviceUS20060142634 *Feb 23, 2006Jun 29, 2006Advanced Resuscitation, LlcSensor-equipped and algorithm controlled direct mechanical ventricular assist deviceUS20060142809 *Nov 22, 2005Jun 29, 2006Kai KrollMedium voltage therapy applications in treating cardiac arrestUS20060167334 *Mar 5, 2004Jul 27, 2006Anstadt Mark PMethod and apparatus for direct mechanical ventricular actuation with favorable conditioning and minimal heart stressUS20070129718 *Aug 31, 2006Jun 7, 2007Medtronic Vascular, Inc.Method for Treating Vulnerable PlaqueUS20090131740 *Jul 11, 2008May 21, 2009Mortiza GharibCardiac assist system using helical arrangement of contractile bands and helically-twisting cardiac assist deviceUS20100152523 *Nov 28, 2006Jun 17, 2010Myocardiocare, Inc.Method and Apparatus for Minimally Invasive Direct Mechanical Ventricular ActuationUS20110196189 *Feb 9, 2010Aug 11, 2011Myocardiocare, Inc.Extra-cardiac differential ventricular actuation by inertial and baric partitioning* Cited by examinerClassifications U.S. Classification607/5International ClassificationA61N1/36, A61N1/365, A61N1/39, A61N1/362Cooperative ClassificationA61N1/36042, A61N1/3962, A61N1/3621European ClassificationA61N1/39M2, A61N1/362A, A61N1/36TLegal EventsDateCodeEventDescriptionJul 30, 2001FPAYFee paymentYear of fee payment: 4Aug 31, 2005REMIMaintenance fee reminder mailedFeb 10, 2006LAPSLapse for failure to pay maintenance feesApr 11, 2006FPExpired due to failure to pay maintenance feeEffective date: 20060210RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services