Source: http://www.patentgenius.com/patent/8457718.html
Timestamp: 2018-09-26 06:19:51
Document Index: 756721620

Matched Legal Cases: ['Application No. 07842741', 'Application No. 07842741', 'Application No. 08743996', 'Application No. 08730689', 'Application No. 08730689', 'Application No. 200780034771', 'Application No. 200880012795', 'Application No. 07842741', 'Application No. 08743996']

Recognizing a real world fiducial in a patient image data - Patent # 8457718 - PatentGenius
Recognizing a real world fiducial in a patient image data
8457718 Recognizing a real world fiducial in a patient image data
Inventor: Voegele, et al.
U.S. Class: 600/426
Field Of Search: 600/426
Foreign Patent Documents: 102005022901; 0920838; 1410758; 1652470; 2779339
Other References: Invitrogen--Qdot In Vivo Imaging, 2006 Introgen Corporation, 5 pages, webpage. cited by applicant.
Kodak--Kodak X-Sight Imaging Agent for In Vivo Applications, 2007, 3 pages, Webpage. cited by applicant.
Hybrid Silica Technologies, Inc.--01. Hybrid Silica Technologies, Inc. (HST) Founded to Commercialize CU Dots Fluorescent Nanoparticles, 2004, by the Office of the Vice Provost for Research, Cornell University, 2 pages, Webpage. cited by applicant.
U.S. Appl. No. 11/524,216, Voegele, James W., Entire. cited by applicant.
Website document of Mimics Software from Materialise (8 pages). cited by applicant.
PCT, International Search Report, PCT/US08/57323 (Aug. 7, 2008). cited by applicant.
PCT, International Search Report, PCT/US08/57322 (Aug. 18, 2008). cited by applicant.
PCT, International Search Report, PCT/US08/56043 (Aug. 26, 2008). cited by applicant.
Supplementary Partial European Search Report, European Patent Application No. 07842741 (8 pages) (Aug. 6, 2009). cited by applicant.
International Search Report, International Application No. PCT/US2008/054933 (3 pages) (mailed Aug. 20, 2008; published Nov. 27, 2008). cited by applicant.
International Search Report, International Application No. PCT/US2007/078832 (2 pages) (mailed Apr. 10, 2008; published Jul. 3, 2008). cited by applicant.
Viergever, M.A. et al., "Integration of functional and anatomical brain images," Biophy. Chem., vol. 68, pp. 207-219 (1997). cited by applicant.
Supplementary Partial European Search Report, European Application No. 07842741.6 (8 pages) (Aug. 6, 2009). cited by applicant.
EP, Supplementary European Search Report, European Application No. 08743996.4 (Apr. 8, 2011). cited by applicant.
EP, Decision to Grant, European Application No. 08730689.0 (Apr. 21, 2011). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2008/056043 (Sep. 15, 2009). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2008/054933 (Sep. 8, 2009). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2007/078832 (Mar. 24, 2009). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2008/057323 (Sep. 22, 2009). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2008/057322 (Sep. 22, 2009). cited by applicant.
US, Office Action, U.S. Appl. No. 11/725,834 (Mar. 22, 2011). cited by applicant.
US, Office Action, U.S. Appl. No. 11/726,653 (Feb. 18, 2011). cited by applicant.
US, Office Action, U.S. Appl. No. 11/820,354 (Jun. 29, 2011). cited by applicant.
US, Office Action, U.S. Appl. No. 11/894,841 (Feb. 25, 2011). cited by applicant.
EP, Supplementary European Search Report, European Application No. 08730689.0; 6 pages (Apr. 28, 2010). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2008/056043; 5 pages (Sep. 15, 2009). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2008/057323; 5 pages (Sep. 22, 2009). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2008/057322; 5 pages (Sep. 22, 2009). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2007/078832; 6 pages (Mar. 24, 2009). cited by applicant.
PCT, International Preliminary Report on Patentability, International Application No. PCT/US2008/054933; 6 pages (Sep. 8, 2009). cited by applicant.
US, Office Action, U.S. Appl. No. 11/716,465; 15 pages (Jun. 24, 2009). cited by applicant.
US, Office Action, U.S. Appl. No. 11/716,465; 11 pages (Mar. 16, 2010). cited by applicant.
US, Office Action, U.S. Appl. No. 11/726,653; 22 pages (May 28, 2010). cited by applicant.
US, Office Action, U.S. Appl. No. 11/524,216; 21 pages (Aug. 19, 2008). cited by applicant.
US, Office Action, U.S. Appl. No. 11/524,216; 20 pages (Jan. 22, 2009). cited by applicant.
US, Advisory Action, U.S. Appl. No. 11/524,216; 3 pages (Apr. 15, 2009). cited by applicant.
US, Office Action, U.S. Appl. No. 11/524,216; 19 pages (Jun. 23, 2009). cited by applicant.
US, Office Action, U.S. Appl. No. 11/524,216; 16 pages (Mar. 3, 2010). cited by applicant.
US, Advisory Action, U.S. Appl. No. 11/524,216; 3 pages (May 11, 2010). cited by applicant.
US, Office Action, U.S. Appl. No. 11/726,653 (Nov. 4, 2010). cited by applicant.
US, Notice of Allowance, U.S. Appl. No. 11/726,653 (Aug. 17, 2011). cited by applicant.
US, Office Action, U.S. Appl. No. 11/894,841 (Sep. 26, 2011). cited by applicant.
CN, Notification of First Office Action, Chinese Application No. 200780034771.0 (Aug. 11, 2010). cited by applicant.
CN, Notification of First Office Action, Chinese Application No. 200880012795.0 (Oct. 20, 2010). cited by applicant.
EP, Office Action, European Application No. 07842741.6 (Oct. 12, 2010). cited by applicant.
EP, Search Report, European Application No. 08743996.4 (Apr. 8, 2011). cited by applicant.
US, Office Action, U.S. Appl. No. 11/894,841 (Nov. 3, 2010). cited by applicant.
US, Office Action, U.S. Appl. No. 11/725,834 (Aug. 1, 2011). cited by applicant.
Abstract: Medical apparatus is described including a fiducial component and a position sensor. The component is recognizable as at least a part of a fiducial when appearing in image data of a patient. The component is attachable to the patient. The sensor is attachable to the component at a predetermined location and orientation on the component or is capable of being positioned adjacent the fiducial component without attachment thereto at a predetermined location and orientation. A storage medium is described containing a program which instructs the computer to recognize a predetermined shape of each of at least one portion of a position sensor as at least a part of a real-world fiducial in image data of a patient. The position sensor is adapted to provide position data. Medical apparatus which includes the position sensor and the storage medium is also described.
1. A medical apparatus comprising a location indicator, a fiducial component, and a position sensor, wherein the location indicator is disposable upon a patient skin surfaceand uniquely indicates a desired orientation of the fiducial component on the skin surface, wherein the fiducial component is recognizable as at least a part of a fiducial when appearing in image data of a patient, wherein the fiducial component isattachable to the patient at the location indicator without piercing the skin surface and is non-destructively separable from the location indicator, wherein the position sensor is attachable to the patient without piercing the skin surface and adaptedto provide position data, wherein the position sensor is adjoinable to the fiducial component without attachment thereto at a predetermined location on the fiducial component and with a predetermined orientation with respect to the fiducial component,and wherein the fiducial component and the position sensor each have a complementary-shaped abutment portion such that mutual abutment without mutual attachment disposes the position sensor at the predetermined location on the fiducial component and withthe predetermined orientation with respect to the fiducial component.
2. A method for using a medical apparatus that comprises a location indicator, a fiducial component, and a position sensor, wherein the location indicator is disposable upon a patient skin surface and uniquely indicates a desired orientation ofthe fiducial component on the skin surface, wherein the fiducial component is recognizable as at least a part of a fiducial when appearing in image data of a patient, wherein the fiducial component is attachable to the patient at the location indicatorand is non-destructively separable from the location indicator, wherein the position sensor is adapted to provide position data, wherein the position sensor is adjoinable to the fiducial component without attachment thereto at a predetermined location onthe fiducial component and with a predetermined orientation with respect to the fiducial component, wherein the fiducial component is attachable to the patient at the location indicator without piercing the skin surface, wherein the position sensor isattachable to the patient without piercing the skin surface, and wherein the position sensor and the fiducial component each have a complementary-shaped abutment portion such that mutual abutment without mutual attachment disposes the position sensor atthe predetermined location on the fiducial component and with the predetermined orientation with respect to the fiducial component, the method comprising the steps of: a) placing the location indicator on the skin surface where the fiducial component isto be attached to the skin surface and so as to indicate the desired orientation of the fiducial component on the skin surface; b) after step a), attaching the fiducial component to the skin surface at the location indicator and with the indicatedorientation; c) after step b), obtaining image data of the patient, wherein the fiducial component appears in the image data; d) after step c), removing the fiducial component from the skin surface while leaving the location indicator on the skinsurface; and e) at a later time after steps a) through d), re-attaching the fiducial component to the skin surface at the location indicator and with the indicated orientation; f) after step e), placing the position sensor on the skin surface, inadjoinment with the fiducial component without attachment thereto at the predetermined location on the fiducial component and with the predetermined orientation with respect to the fiducial component, wherein said adjoinment includes abutting thecomplementary-shaped abutment portion of the position sensor against the complementary-shaped abutment portion of the fiducial component, and creating an image representation of the image data indexed to a reference coordinate system using at least therecognized predetermined shape and a position of the position sensor indexed to the reference coordinate system when the position sensor is in adjoinment with the re-attached fiducial component; and g) after step f), displaying an image of the imagerepresentation.
3. The method of claim 2, wherein step e) is performed at least 24 hours after performing steps a) through d).
4. The method of claim 3, wherein the location indicator is an invisible ink outline of the fiducial component disposed on the skin surface.
5. A medical apparatus comprising a location indicator, a fiducial component, and a position sensor, wherein the location indicator is disposable upon a patient skin surface to present an outline of the fiducial component, wherein the fiducialcomponent has a rotationally asymmetric shape and is recognizable as at least a part of a fiducial when appearing in image data of the patient, wherein the fiducial component is attachable to the patient over or within the location indicator withoutpiercing the skin surface and is non-destructively separable from the location indicator, wherein the position sensor is adapted to provide position data, wherein the position sensor is attachable to the skin surface adjacent the fiducial componentwithout piercing the skin surface and adjoinable to the fiducial component without attachment thereto at a predetermined location on the fiducial component and with a predetermined orientation with respect to the fiducial component, and wherein thefiducial component and the position sensor each have a complementary-shaped abutment portion such that mutual abutment without mutual attachment disposes the position sensor at the predetermined location on the fiducial component and with thepredetermined orientation with respect to the fiducial component.
6. A method for using a medical apparatus that comprises a location indicator, a fiducial component, and a position sensor, wherein the location indicator is disposable upon a patient skin surface to present an outline of the fiducialcomponent, wherein the fiducial component has a rotationally asymmetric shape and is recognizable as at least a part of a fiducial when appearing in image data of the patient, wherein the fiducial component is attachable to the patient over or within thelocation indicator and is non-destructively separable from the location indicator, wherein the position sensor is adapted to provide position data, wherein the position sensor is adjoinable to the fiducial component without attachment thereto at apredetermined location on the fiducial component and with a predetermined orientation with respect to the fiducial component, wherein the fiducial component is attachable to the patient over or within the location indicator without piercing the skinsurface, wherein the position sensor is attachable to the skin surface adjacent the fiducial component without piercing the skin surface, and wherein the fiducial component and the position sensor each have a complementary-shaped abutment portion suchthat mutual abutment without mutual attachment disposes the position sensor at the predetermined location on the fiducial component and with the predetermined orientation with respect to the fiducial component, the method comprising the steps of: a)placing the location indicator on the skin surface where the fiducial component is to be attached to the skin surface, wherein the location indicator is an outline, having a rotationally asymmetric shape matching the rotationally asymmetric shape of thefiducial component, that indicates a desired orientation of the fiducial component on the skin surface; b) after step a), attaching the fiducial component to the skin surface at the location indicator and with the indicated orientation; c) after stepb), obtaining image data of the patient, wherein the fiducial component appears in the image data; d) after step c), removing the fiducial component from the skin surface while leaving the location indicator on the skin surface; and e) at a later timeafter steps a) through d), re-attaching the fiducial component to the skin surface at the location indicator and with the indicated orientation; f) after step e), placing the position sensor on the skin surface, in adjoinment with the fiducial componentwithout attachment thereto at the predetermined location on the fiducial component and with the predetermined orientation with respect to the fiducial component, wherein said adjoinment includes abutting the complementary-shaped abutment portion of theposition sensor against the complementary-shaped abutment portion of the fiducial component, and creating an image representation of the image data indexed to a reference coordinate system using at least the recognized predetermined shape and a positionof the position sensor indexed to the reference coordinate system when the position sensor is disposed in adjoinment with the re-attached fiducial component; and g) after step f), displaying an image of the image representation.
7. The method of claim 6, wherein step e) is performed at least 24 hours after performing steps a) through d).
8. The method of claim 7, wherein the location indicator is an invisible ink outline of the fiducial component disposed on the skin surface.
9. The method of claim 3, wherein the location indicator is a clear adhesive decal outline of the fiducial component disposed on the skin surface.
10. The method of claim 3, wherein the placing of the location indicator includes placing an outline of the fiducial component on the patient skin surface in an invisible ink.
11. The method of claim 7, wherein the location indicator is a clear adhesive decal outline of the fiducial component disposed on the skin surface.
12. The method of claim 7, wherein the placing of the location indicator includes placing an outline of the fiducial component on the patient skin surface in an invisible ink.
13. The medical apparatus of claim 1, wherein the complementary-shaped abutment portions are outermost peripheral surfaces of the respective fiducial component and position sensor.
14. The method of claim 2, wherein the complementary-shaped abutment portions are outermost peripheral surfaces of the respective fiducial component and position sensor.
15. The medical apparatus of claim 5, wherein the complementary-shaped abutment portions are outermost peripheral surfaces of the respective fiducial component and position sensor.
16. The method of claim 6, wherein the complementary-shaped abutment portions are outermost peripheral surfaces of the respective fiducial component and position sensor.
Imagers are known for obtaining image data of a patient and for displaying images of the image data on a display monitor. Such images include, without limitation, ultrasound images, X-ray images, computerized tomography (CT) images, positiveelectron emission (PET) images, magnetic resonance (MRI) images, fluoroscope images, etc. Where needed, it is known to register these images with a real world object by placing a fiducial component on the skin of the patient, wherein the fiducialcomponent has a predetermined shape, and wherein the fiducial component is recognizable as a fiducial in the image data using pattern recognition software (e.g., a conventional segmentation subroutine).
Position sensors are known which are placed on medical instruments which are inserted into a patient allowing the position of the medical instrument to be tracked inside the patient. Such position sensors are part of known position sensingsystems such as an AC-based system available from Biosense-Webster or a DC-based system available from Ascension Technology Corporation.
A first expression of a first embodiment of the invention is for medical apparatus including a fiducial component and a position sensor. The fiducial component is recognizable as at least a part of a fiducial when appearing in image data of apatient. The fiducial component is attachable to the patient. The position sensor is adapted to provide position data. The position sensor is attachable to the fiducial component at a predetermined location on the fiducial component and with apredetermined orientation with respect to the fiducial component.
A first expression of a second embodiment of the invention is for medical apparatus including a fiducial component and a position sensor. The fiducial component is recognizable as at least a part of a fiducial when appearing in image data ofthe patient. The fiducial component is attachable to the patient. The position sensor is adapted to provide position data. The position sensor is positionable (i.e., capable of being positioned) adjacent the fiducial component without attachmentthereto at a predetermined location on the fiducial component and with a predetermined orientation with respect to the fiducial component.
A first expression of a third embodiment of the invention is for a storage medium containing a program readable by a digital computer which instructs the digital computer to recognize a predetermined shape of each of at least one portion of aposition sensor as at least a part of a real-world fiducial in image data of a patient when the image data includes the predetermined shape and is received as an input by the digital computer. The position sensor is adapted to provide position data.
A second expression of a third embodiment of the invention is for medical apparatus comprising a position sensor and a storage medium. The position sensor has at least one portion each with a predetermined shape. The storage medium contains aprogram readable by a digital computer which instructs the digital computer to recognize the predetermined shape of each of the at-least-one portion as at least a part of a real-world fiducial in image data of a patient when the image data includes thepredetermined shape and is received as an input by the digital computer. The position sensor is adapted to provide position data.
Several benefits and advantages are obtained from one or more of the embodiments of the invention. In one example of the first and/or second embodiment, image data is related to the fiducial component, the fiducial component is related to theposition of the position sensor, and the position of the position sensor is related to a reference coordinate system allowing the creation of an image representation of the image data registered to the reference coordinate system and a display of animage of the image representation. In one variation, the fiducial component is attachable to the skin surface of the patient, the image data is obtained, and the fiducial component is removed and reattached to the same skin surface days later afterwhich the image representation is created when the position of the attached/disposed sensor is indexed to the reference coordinate system and an image of the image representation is displayed and used while medically treating the patient. In one medicaltreatment, a medical instrument has its own position sensor, and an image of at least a part of the medical instrument is created and displayed superimposed on the image of the patient. An example of the third embodiment can be similarly employed.
FIG. 1 is a schematic view of a first embodiment of the invention showing medical apparatus including a top planar view of a fiducial component and a position sensor (both shown in large scale), wherein the fiducial component is attached to apatient, and the position sensor is attached to the fiducial component;
FIG. 2 is a schematic view a portion of FIG. 1 showing a top planar view of the location indicator on the patient, showing a top planar view of the fiducial component with its pin holes, and showing a bottom planar view of the position sensorwith its pins, wherein the position sensor is not yet attached to the fiducial component and the fiducial component is not yet attached to the patient;
FIG. 3 is a schematic view of a display monitor upon which a digital computer displays an image of an image representation of image data of the patient registered to a reference coordinate system, wherein the fiducial component of FIG. 1 isshown in the image;
FIG. 4 is a schematic view of a second embodiment of the invention showing medical apparatus including a top planar view of a fiducial component and a position sensor (both shown in large scale), wherein the fiducial component is attached to apatient, and the position sensor is disposed adjacent the fiducial component without attachment thereto;
FIG. 5 is a schematic view of a portion of FIG. 3 showing a top planar view of the location indicator on the patient, showing a top planar view of the fiducial component, and showing a top planar view of the position sensor, wherein the positionsensor is not yet disposed adjacent the fiducial component and the fiducial component is not yet attached to the patient;
FIG. 6 is a schematic view of a display monitor upon which a digital computer displays an image of an image representation of image data of the patient registered to a reference coordinate system, wherein the fiducial component of FIG. 4 isshown in the image;
FIG. 9 is a schematic view of a display monitor upon which a digital computer displays an image of an image representation of image data of the patient registered to a reference coordinate system, wherein the position sensor of FIG. 7 is shownin the image.
Before explaining the several embodiments of the present invention in detail, it should be noted that the present invention is not limited in its application or use to the details of construction and arrangement of parts and steps illustrated inthe accompanying drawings and description. The illustrative embodiments of the invention may be implemented or incorporated in other embodiments, methods, variations and modifications, and may be practiced or carried out in various ways. Furthermore,unless otherwise indicated, the terms and expressions employed herein have been chosen for the purpose of describing the illustrative embodiments of the present invention for the convenience of the reader and are not for the purpose of limiting theinvention.
A first embodiment of the invention is shown in FIGS. 1-3. A first expression of the embodiment of FIGS. 1-3 is for medical apparatus 10 including a fiducial component 12 and a position sensor 14. The fiducial component 12 is recognizable asat least a part of a fiducial when appearing in image data 16 of a patient 18. The fiducial component 12 is attachable to the patient 18. The position sensor 14 is adapted to provide position data. The position sensor 14 is attachable to the fiducialcomponent 12 at a predetermined location on the fiducial component 12 and with a predetermined orientation with respect to the fiducial component 12. It is noted that the fiducial component 12 has a predetermined shape which is recognizable as a"manufactured" shape as opposed to biological shapes occurring in image data of a patient. It is also noted that the position sensor 14 may be a wired or wireless sensor.
Examples of position sensors 14 adapted to provide position data include, without limitation, the position sensors of the AC-based position sensing system available from Biosense-Webster and the DC-based position sensing system available fromAscension Technology Corporation. It is noted that, as used in describing the embodiment of FIGS. 1-3, the term "position" includes up to six degrees of freedom so that calculating position includes calculating a two-dimensional or three-dimensionallocation (translation) and two or three degrees of orientation (alignment) of the sensor 14 with respect to a reference coordinate system. A description of the operation of an embodiment of a position sensor 14 adapted to provide position data is foundin US Patent Application Publication 2006/0089624.
Examples of image data 16 include, without limitation, ultrasound image data, X-ray image data, computerized tomography (CT) image data, positive electron emission (PET) image data, magnetic resonance (MRI) image data, and fluoroscope imagedata. An example of a computer program which creates a manipulative 3D display image from 2D CT-scans and MRI-scans is Mimics available from Materialise of Ann Arbor, Mich.
In one enablement of the embodiment of FIGS. 1-3, the position sensor 14 is attached to the fiducial component 12. In one variation, the attachment is a temporary attachment meaning that the position sensor 14 can be detached from the fiducialcomponent 12 without damage to either or both of the position sensor 14 and the fiducial component 12. In another variation, the attachment is a permanent attachment meaning that the position sensor 14 cannot be detached from the fiducial component 12without damage to either or both of the position sensor 14 and the fiducial component 12.
In one implementation of the embodiment of FIGS. 1-3, the fiducial component 12 is recognizable as the fiducial. In one variation a portion of the overall shape of the fiducial component 12 is recognizable as the fiducial. In anothervariation, the overall shape of the fiducial component 12 is recognizable as the fiducial. In another implementation, it is the presence together of the fiducial component 12 (or a portion or portions thereof) and the position sensor 14 (or a portion orportions thereof) which is recognizable as the fiducial. In either or both implementations, separate portions may be recognized as separate fiducials.
In a first arrangement of the embodiment of FIGS. 1-3, the patient 18 has skin 20, wherein the skin 20 has a skin surface 22, wherein the fiducial component 12 is attachable to the skin surface 22 without piercing the skin surface 22, andwherein the position sensor 14 is attachable to the fiducial component 12 without piercing the skin surface 22. In one variation, the fiducial component 12 is adhesively attached to the skin surface 22. In the same or a different variation, theposition sensor 14 has pins 15, the fiducial component 12 has pin holes 13, and the pins 15 are attachingly engagable with the pin holes 13. In one modification, not shown, the position sensor has a sensor body and a sensor, wherein the sensor body hasa sensor location and rotational orientation feature such that the sensor is attachable to the sensor body only at the sensor location and with the rotational orientation. Other attachment variations and other modifications are left to the artisan.
A first method of the invention is for using the first arrangement of the medical apparatus 10 and includes steps a) through g). Step a) includes placing a location indicator 24 on the skin surface 22 where the fiducial component 12 is to beattached to the skin surface 22, wherein the location indicator 24 also indicates a desired orientation of the fiducial component 12 on the skin surface 22. Step b) includes, after step a), attaching the fiducial component 12 to the skin surface 22 atthe location indicator 24 and with the desired orientation. Step c) includes, after step b), obtaining image data 16 of the patient 18, wherein the fiducial component 12 appears in the image data 16. Step d) includes, after step c), removing thefiducial component 12 from the skin surface 22 while leaving the location indicator 24 on the skin surface 22. Step e) includes, at a later time after steps a) through d), re-attaching the fiducial component 12 to the skin surface 22 at the locationindicator 24 and with the desired orientation. Step f) includes, after step e), creating an image representation of the image data 16 indexed to a reference coordinate system using at least the recognized predetermined shape and a position of theposition sensor 14 indexed to the reference coordinate system when the position sensor 14 is attached to the re-attached fiducial component 12. Step g) includes, after step f), displaying an image 26 of the image representation. It is noted that stepc) may be performed with or without the position sensor 14 attached to the fiducial component 12.
In one realization of the first method, the position data and/or the image data 16 are already indexed and step e) does not perform such indexing. In a different realization of the first method, the position data and/or the image data 16 arenot yet indexed, and step e) performs such indexing.
In one illustration of the first method, the position sensor 14 is considered to be a position sensor of a Biosense Webster positioning sensing system and a transmitter, not shown, of such system is used by a digital computer for a referencecoordinate system for position data from the position sensor 14. Thus, the position of the position sensor 14 can be indexed to the reference coordinate system. Since the image data 16 is related to the fiducial component 12 which has a predeterminedposition with respect to the attached position sensor 14, an image representation of the image 26 can be created which is registered to the reference coordinate system.
In one employment of the first method, step g) displays the image 26 on a display monitor 28. Examples of a display monitor 42 include, without limitation, a computer monitor, a goggle display screen, and a room wall upon which projected imagesare displayed. In one variation, a storage medium 30 contains a program readable by a digital computer 32 which instructs the digital computer 32 to perform steps f) and g) of the first method.
In one example, the image 26 is a three-dimensional manipulative image, and there is also included a computer input device 34 operatively connected to the digital computer 32 to allow a user to manipulate the three-dimensional-manipulative imageon the display monitor 28. Examples of input devices 34 include, without limitation, a keyboard and a mouse. In a different example, the image is a two-dimensional non-manipulative image.
In one variation of the first method, step e) is performed at least 24 hours after performing steps a) through d). In the same or a different variation, the location indicator 24 is an invisible ink outline of the fiducial component 12 on theskin surface 22 (such as the ultraviolet-ink outline made visible under ultraviolet light as seen in FIG. 2) or is a clear adhesive decal outline of the fiducial component on the skin surface. In one modification, the outline is asymmetric and matchesthe asymmetric shape of the fiducial component 12 for proper location and alignment of the fiducial component 12 on the skin surface 22. In the same or a different variation, the first method also includes the step of performing a medical treatment(such as a surgical treatment) of the patient 18 while viewing the displayed image 26. In one medical treatment, not shown, a medical instrument has its own position sensor, and an image of at least a part of the medical instrument is created anddisplayed superimposed on the image 26 of the patient 18. Other variations and modifications are left to the artisan including performing step e) at least 15 minutes after performing steps a) through d) or performing step e) at a shorter or longer timeinterval after performing steps a) through d). In one example, without limitation, a person who has had MRI or CT images taken in an imaging area of a medical facility where steps a) through d) were performed is then quickly moved to a surgical area ofthe medical facility where steps e) through g) are performed.
In a second arrangement of the embodiment of FIGS. 1-3, not shown, the fiducial component is attachable to an internal skeletal feature of the patient. In a third arrangement, not shown, the fiducial component is attachable to the patient belowthe skin of the patient, and the position sensor has at least one portion adapted for piercing the skin for attaching to the fiducial component. In a fourth arrangement, the fiducial component is attachable to the patient within the skin of the patient,and the position sensor has at least one portion adapted for piercing the skin surface for attaching to the fiducial component. In a fifth arrangement, the fiducial component is attachable to orthopedic hardware of the patient.
A second embodiment of the invention is shown in FIGS. 4-6. A first expression of the embodiment of FIGS. 4-6 is for a medical apparatus 110 including a fiducial component 112 and a position sensor 114. The fiducial component 112 isrecognizable as at least a part of a fiducial when appearing in image data 116 of a patient 118. The fiducial component 112 is attachable to the patient 118. The position sensor 14 is adapted to provide position data. The position sensor 114 isdisposable adjacent the fiducial component 112 without attachment thereto at a predetermined location on the fiducial component 112 and with a predetermined orientation with respect to the fiducial component 112. It is noted that the fiducial component112 has a predetermined shape which is recognizable as a "manufactured" shape as opposed to biological shapes occurring in image data of a patient.
In one enablement of the embodiment of FIGS. 4-6, the position sensor 114 is disposed adjacent the fiducial component 112 without attachment thereto at the predetermined location on the fiducial component 112 and with the predeterminedorientation with respect to the fiducial component 112.
In a first arrangement of the embodiment of FIGS. 4-6, the patient 118 has skin 120, wherein the skin 120 has a skin surface 122, wherein the fiducial component 112 is attachable to the skin surface 122 without piercing the skin surface 122, andwherein the position sensor 114 is attachable to the skin surface 122 adjacent the fiducial component 112 without piercing the skin surface 122. In one variation, the fiducial component 112 and the position sensor 114 each are adhesively attached to theskin surface 122. In the same or a different variation, the position sensor 114 and the fiducial component 112 each have a complementary-shaped portion which allows the position sensor 114 to be disposed adjacent the fiducial component 112 at a desiredlocation on the fiducial component 112 and with a desired alignment with respect to the fiducial component 112.
A second method of the invention is for using the first arrangement of the medical apparatus 110 and includes steps a) through g). Step a) includes placing a location indicator 124 on the skin surface 122 where the fiducial component 112 is tobe attached to the skin surface 122, wherein the location indicator 124 also indicates a desired orientation of the fiducial component 112 on the skin surface 122. Step b) includes, after step a), attaching the fiducial component 112 to the skin surface122 at the location indicator 124 and with the desired orientation. Step c) includes, after step b), obtaining image data 116 of the patient 118, wherein the fiducial component 112 appears in the image data 116. Step d) includes, after step c),removing the fiducial component 112 from the skin surface 122 while leaving the location indicator 124 on the skin surface 122. Step e) includes, at a later time after steps a) through d), re-attaching the fiducial component 112 to the skin surface 122at the location indicator 124 and with the desired orientation. Step f) includes, after step e), creating an image representation of the image data 116 indexed to a reference coordinate system using at least the recognized predetermined shape and aposition of the position sensor 114 indexed to the reference coordinate system when the position sensor 114 is disposed adjacent the re-attached fiducial component 112. Step g) includes, after step f), displaying an image 126 of the imagerepresentation. It is noted that step c) may be performed with or without the position sensor 114 disposed adjacent (e.g., on the side or top surface of) the re-attached fiducial component 112 at the desired location on the fiducial component 112 andwith the desired alignment with respect to the fiducial component 112.
In one illustration of the second method, the position sensor 114 is considered to be a position sensor of a Biosense Webster positioning sensing system and a transmitter, not shown, of such system is used by a digital computer for a referencecoordinate system for position data from the position sensor 114. Thus, the position of the position sensor 114 can be indexed to the reference coordinate system. Since the image data 116 is related to the fiducial component 112 which has apredetermined position with respect to the properly adjacently disposed position sensor 114, an image representation of the image 126, can be created which is registered to the reference coordinate system.
In one employment of the second method, step g) displays the image 126 on a display monitor 128. In one variation, a storage medium 130 contains a program readable by a digital computer 132 which instructs the digital computer 132 to performsteps f) and g) of the second method.
In one example, the image 126 is a three-dimensional manipulative image, and there is also included a computer input device 134 operatively connected to the digital computer 132 to allow a user to manipulate the three-dimensional-manipulativeimage on the display monitor 128. In a different example, the image is a two-dimensional non-manipulative image.
In one variation of the second method, step e) is performed at least 24 hours after performing steps a) through d). In the same or a different variation, the location indicator 124 is an invisible ink outline of the fiducial component 112 onthe skin surface 122 (such as the ultraviolet-ink outline made visible under ultraviolet light as seen in FIG. 5) or is a clear adhesive decal outline of the fiducial component on the skin surface. In one modification, the outline is asymmetric andmatches the asymmetric shape of the fiducial component 112 for proper location and alignment of the fiducial component 112 on the skin surface 122. In the same or a different variation, the second method also includes the step of performing a medicaltreatment (such as a surgical treatment) of the patient 118 while viewing the displayed image 126. In one medical treatment, not shown, a medical instrument has its own position sensor, and an image of at least a part of the medical instrument iscreated and displayed superimposed on the image 126 of the patient 118.
A third embodiment of the invention is shown in FIGS. 7-9. A first expression of the embodiment of FIGS. 7-8 is for a storage medium 230 containing a program readable by a digital computer 232 which instructs the digital computer 232 torecognize a predetermined shape of each of at least one portion of a position sensor 214 as at least a part of a real-world fiducial in image data 216 of a patient 218 when the image data 216 includes the predetermined shape and is received as an inputby the digital computer 232. The position sensor 214 is adapted to provide position data. It is noted that the words "at least one portion" includes "the entirety". In one example, the program includes a conventional segmentation subroutine toidentify the predetermined shape.
In one enablement of the first expression of the embodiment of FIGS. 7-9, the at-least-one portion is adapted to have a fixed position relative to the patient 218 during a medical treatment of the patient 218. In the same or a differentenablement, the program instructs the digital computer 232 to create an image representation of the image data 216 indexed to a reference coordinate system using at least the recognized predetermined shape and a position of the position sensor indexed tothe reference coordinate system, and the program instructs the digital computer 232 to display an image 226 (such as on a display monitor 228) of the image representation. It is noted that code can be written by those of ordinary skill in the art,without undue experimentation, which instructs the digital computer 132 to create the image representation of the image data 116 indexed to the reference coordinate system.
In one extension of the first expression of the embodiment of FIGS. 7-9, a location indicator 224 (similar to the previously described location indicators 24 and 124) is disposed on the patient 218, and the position sensor 214 is disposable onthe patient 218 on, and alignable with, the location indicator 224.
A second expression of the embodiment of FIGS. 7-9 is for medical apparatus 210 including a position sensor 214 and a storage medium 230. The position sensor 214 has at least one portion each with a predetermined shape. The storage medium 230contains a program readable by a digital computer 232 which instructs the digital computer 232 to recognize the predetermined shape of each of the at-least-one portion as at least a part of a real-world fiducial in image data 216 of a patient 218 whenthe image data 216 includes the predetermined shape and is received as an input by the digital computer 232. The position sensor 214 is adapted to provide position data.
While the present invention has been illustrated by several embodiments and methods, and enablements, applications, etc. thereof, it is not the intention of the applicants to restrict or limit the spirit and scope of the appended claims to suchdetail. Numerous other variations, changes, and substitutions will occur to those skilled in the art without departing from the scope of the invention. It will be understood that the foregoing description is provided by way of example, and that othermodifications may occur to those skilled in the art without departing from the scope and spirit of the appended Claims.
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