Source: http://www.google.com/patents/US20080208076?dq=5,241,671
Timestamp: 2014-04-24 06:04:00
Document Index: 533201349

Matched Legal Cases: ['art. 2', 'art 120', 'arts 120', 'arts 120', 'art 120', 'art 122', 'art 123', 'art 120', 'art 120', 'art 120', 'art 123', 'arts 123', 'art 120', 'arts 120', 'art 120', 'art 120', 'art 110', 'art 110', 'art 110', 'art 110', 'art 120', 'arts 120', 'arts 123', 'arts 123']

Patent US20080208076 - Barb-wired micro needle made of single crystalline silicon and biopsy method ... - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsDisclosed are a barb-wired single crystalline silicon micro needle and a biopsy method and a medicine injecting method using the same. The micro needle comprises a main body part, at least one extension part formed on a side surface of the main body part, and a protrusion part protruded from both side...http://www.google.com/patents/US20080208076?utm_source=gb-gplus-sharePatent US20080208076 - Barb-wired micro needle made of single crystalline silicon and biopsy method and medicine injecting method using the sameAdvanced Patent SearchPublication numberUS20080208076 A1Publication typeApplicationApplication numberUS 12/069,592Publication dateAug 28, 2008Filing dateFeb 12, 2008Priority dateAug 18, 2005Also published asUS8118753Publication number069592, 12069592, US 2008/0208076 A1, US 2008/208076 A1, US 20080208076 A1, US 20080208076A1, US 2008208076 A1, US 2008208076A1, US-A1-20080208076, US-A1-2008208076, US2008/0208076A1, US2008/208076A1, US20080208076 A1, US20080208076A1, US2008208076 A1, US2008208076A1InventorsDong-Il Cho, Seung Joon Paik, Jung Min Lim, Ah Ra Lee, Sang Won Byun, Kyo-In KooOriginal AssigneeSeoul National University Industry FoundationExport CitationBiBTeX, EndNote, RefManReferenced by (1), Classifications (8), Legal Events (1) External Links: USPTO, USPTO Assignment, EspacenetBarb-wired micro needle made of single crystalline silicon and biopsy method and medicine injecting method using the sameUS 20080208076 A1Abstract Disclosed are a barb-wired single crystalline silicon micro needle and a biopsy method and a medicine injecting method using the same. The micro needle comprises a main body part, at least one extension part formed on a side surface of the main body part, and a protrusion part protruded from both side surfaces of the extension part. A medicine storage is formed on a surface of the main body part. A fluid passage is formed in the extension part and the main body part. It is easy to pick the tissue sample with the protrusion part just by inserting and extracting the extension part of the micro needle into and from the tissue for a biopsy. Therefore, the biopsy procedures can be simplified. In addition, the medicine in the storage can be injected into the tissue via the fluid passage.
a main body part capable of being insertion-mounted to a medical device and inserted into the body along with said medical device for picking a tissue sample from an organ in a body, the main body part including a medicine storage formed on a portion of one surface thereof and having a recess shape for storing medicine and a fluid passage formed therein to communicate with the medicine storage and made of single crystalline silicon; plural extension parts integrally extending from a side surface of the main body part, provided with the fluid passage therein and inserted into a biopsy tissue; and plural protrusion parts integrally protruding from a side surface or both side surfaces of the extension parts, and picking the biopsy tissue, wherein plural outflow ports of the fluid passage are formed on both side surfaces of each of the extension part. 2. The micro needle according to claim 1, wherein the protrusion part is formed into a shape of a wing.
4. The micro needle according to claim 1, wherein the protrusion part has a width of 5 micrometer�5 millimeter, a space of 5 micrometer�5 millimeter, and a height of 5 micrometer�5 millimeter.
5. The micro needle according to claim 1, wherein the protrusion part has a width of 50 micrometer�1 millimeter, a space of 50 micrometer�1 millimeter, and a height of 50 micrometer�1 millimeter.
a main body part capable of being insertion-mounted to a medical device and inserted into the body along with said medical device for picking a tissue sample from an organ in a body, the main body part including a medicine storage formed on a portion of one surface thereof and having a recess shape for storing medicine and a fluid passage formed therein to communicate with the medicine storage and made of single crystalline silicon; plural extension parts integrally extending from a side surface of the main body part, provided with the fluid passage therein and inserted into a biopsy tissue; and plural protrusion parts integrally protruding from a side surface or both side surfaces of the extension parts which are opposite to each other, and picking the biopsy tissue, wherein plural outflow ports of the fluid passage are formed on both side surfaces of each of the extension parts. 19. A barb-wired micro needle monolithically formed from a single crystalline silicon comprising:
a main body part capable of being insertion-mounted to a medical device and inserted into the body along with said medical device for picking a tissue sample from an organ in a body, the main body part including a medicine storage formed on a portion of one surface thereof and having a recess shape for storing medicine and a fluid passage formed therein to communicate with the medicine storage and made of single crystalline silicon; plural extension parts integrally extending from a side surface of the main body part, provided with the fluid passage therein and inserted into a biopsy tissue; and plural protrusion parts integrally protruding from a side surface or both side surfaces of the extension parts which are opposite to each other, and picking the biopsy tissue, wherein plural outflow ports of the fluid passage are formed on both side surfaces of each of the extension parts, and wherein at least two pairs of extension parts are integrally extended from upper and lower parts of one side of the main body part, wherein a pair of extension parts consists of two extension parts, one of which is extended from a left part of the one side of the main body part, and the other of which is extended from a right part of the one side of the main body part. Description
For solving the above problems, there are suggested micro biopsy/precision cutting devices made by applying a micro machining process and a precision process. The devices are disclosed in, for example, U.S. Pat. No. 5,928,161 (Krulevitch, et al.) entitled �Microbiopsy/Precision Cutting Devices.�
SUMMARY OF THE INVENTION Accordingly, the present invention has been made to solve the above-mentioned problems occurring in the prior art. The object of the present invention is to manufacture a micro needle as a biopsy device using a silicon micromachining process to miniaturize the micro needle, thereby performing a micro biopsy for a target tissue and minimizing an invasion of the biopsy device for a patient.
The protrusion part may have a width of approximately 5 μm�5 mm, a space of approximately 5 μm�5 mm, and a height of approximately 5 μm�5 mm. Preferably, the protrusion part may have a width of approximately 50 μm�1 mm, a space of approximately 50 μm�1 mm, and a height of approximately 50 μm�1 mm.
According to the invention, two or more extension parts may be formed on the main body part. The extension parts may have a length of approximately 1.5 mm�15 mm and be formed apart from each other at an interval of approximately 5 μm�30 mm. Preferably, the extension part may have a length of approximately 2 mm�10 mm and be formed at an interval of approximately 100 μm�5 mm.
It can be determined that a length (L) of the extension part 120 is within a range of about 10 μm�10 mm, and a space (t) between the extension parts 120 is within a range of about 5 μm�5 mm. Although only three extension parts 120 are shown in FIG. 1 for convenient explanations, it should be noted that two or more extension part 120 can be provided.
The protrusion part 122 may be formed into various shapes as shown in FIGS. 4A to 4F. Specifically, a protrusion part 123 a may have a wing shape inclined in a forward direction for a longitudinal direction of the extension part 120 toward the leading portion 121 of the extension part 120, and may be integratedly protruded from both side surfaces of the extension part 120, as shown in FIG. 4A. It can be determined that a width (W) of the protrusion part 123 a, a space (D) between the protrusion parts, and a height (H) of the protrusion part are within a range of about 5 μm�5 mm, respectively.
Additionally, similarly to the protrusion part shown in FIG. 4A, it can be determined that a width, a space and a height of the protrusion parts 123 a, 123 b, 124, 125, 126 shown in FIGS. 4B to 4F are within a range of about 5 μm�5 mm.
In the mean time, considering a characteristic of a device being inserted into a living body, a size thereof is preferably limited within a predetermined range. From this point of view, it is preferred that a length (L in FIG. 1B) of the extension part 120 is within a range of 1.5 mm�15 mm (more preferably, 2 mm�10 mm), and an interval (t in FIG. 1A) between the extension parts 120 is within a range of 5 μm(micrometer)�30 mm (more preferably, 100 μm�5 mm). Further, it is preferred that the width (k in FIG. 4A) of said extension part 120 is within a range of 10 μm�10 mm (more preferably, 100 μm�1 mm). Further, it is also preferred that the thickness (d in FIG. 2B) of said extension part 120 is within a range of 10 μm�10 mm (more preferably, 100 μm�1 mm).
Further, the main body part 110 of a micro needle 100 according to the invention is also inserted into the body by a medical device, and therefore, it is preferable that the size of said main body part 110 be limited to a certain range. For instance, it is preferred that the width (x in FIG. 1A) be within the range of 100 μm�50 mm (more preferably 1 mm�5 mm). It is preferred that the length (y in FIG. 1B) of said main body part 110 also be limited to 100 μm�50 mm (more preferably 500 μm�5 mm). It is preferred that the thickness (z in FIG. 1B) of said main body part 110 be limited to 100 μm�10 mm (more preferably 200 μm�2 mm).
In the mean time, the film 47 consists of a film capable of being deposited by the low pressure chemical vapor deposition method, for example, one or more of a polycrystalline silicon film, a silicon oxide film and a silicon nitride film. In addition, instead of using the low pressure chemical vapor deposition method for sealing the trench 41 hermetically, a coating process using a bio-compatible organic thin film such as a parylene thin film may be used. Additionally, separating from the process described in connection with FIG. 7B or 7C, when the silicon substrate 1 is heat-treated in a hydrogen atmosphere and a temperature of 1100� C. after the trench 41 is formed, the crystals are re-combined and thus an upper part of the trench 41 is hermetically sealed. The fluid passage 45 may be formed using such phenomenon.
It can be determined that a length (L) of the extension part 120 is within a range of about 1.5 mm�15 mm, and a space (t) of the extension parts 120 is within a range of about 5 μm�30 mm.
In addition, the protrusion part may be formed into various shapes as well as the shapes of the wing-shaped, semicircular, quadrangle and triangular protrusion parts 123 a, 123 b, 124, 125, 126 as shown in FIGS. 4A to 4F. The width (W), the space (D) and the height (H) of the protrusion parts 123 a, 123 b, 124, 125, 126 may be set to be within a range of about 5 μm�5 mm.
Referenced byCiting PatentFiling datePublication dateApplicantTitleWO2013036992A1 *Sep 12, 2012Mar 21, 2013Ssb Technology Pty LtdComposite cannula* Cited by examinerClassifications U.S. Classification600/562International ClassificationA61B10/00Cooperative ClassificationA61M2037/0053, A61B10/0233, A61M37/0015, A61M2037/003European ClassificationA61M37/00M, A61B10/02PLegal EventsDateCodeEventDescriptionApr 29, 2008ASAssignmentOwner name: SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION,KOREFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:CHO, DONG-IL;PAIK, SEUNG JOON;LIM, JUNG MIN AND OTHERS;US-ASSIGNMENT DATABASE UPDATED:20100329;REEL/FRAME:20872/514Effective date: 20080310Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:CHO, DONG-IL;PAIK, SEUNG JOON;LIM, JUNG MIN;AND OTHERS;REEL/FRAME:020872/0514Owner name: SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION, KORRotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google