Source: http://www.google.com/patents/US8124800?dq=inassignee:Temic
Timestamp: 2014-03-13 14:47:08
Document Index: 675369214

Matched Legal Cases: ['Application No. 08700247', 'Application No. 05758938', 'Application No. 05758938', 'Application No. 553147', 'Application No. 553147', 'Application No. 553147', 'Application No. 593529', 'Application No. 586503', 'Application No. 593529', 'Application No. 578947', 'Application No. 578947', 'Application No. 2007200090', 'Application No. 08700247', 'Application No. 200580029218', 'Application No. 211795', 'Application No. 200580029218', 'Application No. 180628', 'Application No. 2007105097', 'Application No. 2007105097', 'Application No. 05758938', 'Application No. 08700247', 'Application No. 2007200090', 'Application No. 578947', 'Application No. 2007', 'Application No. 586503', 'Application No. 200580029218', 'Application No. 2007105097', 'Application No. 180628', 'Application No. 553147', 'Application No. 578947', 'Application No. 05758938', 'Application No. 08700247', 'Application No. 553147', 'Application No. 05758938', 'Application No. 08700247', 'Application No. 2007', 'Application No. 2007', 'Application No. 200580029218', 'Application No. 201010128184']

Patent US8124800 - Process for the preparation of oxidized phospholipids - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsNovel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic...http://www.google.com/patents/US8124800?utm_source=gb-gplus-sharePatent US8124800 - Process for the preparation of oxidized phospholipidsAdvanced Patent SearchPublication numberUS8124800 B2Publication typeGrantApplication numberUS 12/861,921Publication dateFeb 28, 2012Filing dateAug 24, 2010Priority dateJul 9, 2004Also published asCA2674902A1, CN101679463A, EP2125838A2, EP2125838A4, EP2522672A1, US7807847, US20070112211, US20100317881, US20120130108, US20130158283, US20130190523, WO2008084472A2, WO2008084472A3Publication number12861921, 861921, US 8124800 B2, US 8124800B2, US-B2-8124800, US8124800 B2, US8124800B2InventorsGideon Halperin, Eti Kovalevski-IshaiOriginal AssigneeVascular Biogenics Ltd.Export CitationBiBTeX, EndNote, RefManPatent Citations (17), Non-Patent Citations (60), Referenced by (3), Classifications (19), Legal Events (2) External Links: USPTO, USPTO Assignment, EspacenetProcess for the preparation of oxidized phospholipidsUS 8124800 B2Abstract Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone, which are devoid of column chromatography are disclosed. Further disclosed are novel methods of introducing phosphorous-containing moieties such as phosphate moieties to compounds having glycerolic backbone and intermediates formed thereby.
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KurtzMethod for treating periodontal diseaseUS6414168Dec 28, 1999Jul 2, 2002Caschem, Inc.Epoxidation of ricinic compounds using a phase-transfer catalystUS6838452 *May 27, 2003Jan 4, 2005Vascular Biogenics Ltd.Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosisCH642665A5 Title not availableWO1995023592A1Mar 3, 1995Sep 8, 1995Univ British ColumbiaLiposome compositions and methods for the treatment of atherosclerosisWO2002041827A2Nov 22, 2001May 30, 2002Cardimmune LtdMethods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosisWO2004106486A2May 27, 2004Dec 9, 2004Vascular Biogenics LtdOxidized lipids and uses thereof in the treatment of inflammatory diseases and disordersWO2008084472A2Jan 2, 2008Jul 17, 2008Vascular Biogenics LtdImproved process for the preparation of oxidized phospholipids* Cited by examinerNon-Patent CitationsReference1"The Nomenclature of Lipids", Journal of Lipid Research, vol. 8: 523-528,1967. e-mail pdf of Jul. 29, 2011 (Filing) in 46755.2Boullier et al. "The Binding of Oxidized Low Density Lipoprotein to Mouse CD36 Is Mediated in Part by Oxidized Phospholipids That Are Associated With Both the Lipid and Protein Moieties of the Lipoprotein",Jornal of Biological Chemistry, vol. 275 (13) p. 9163-9169, 2000.3Communication Pursuant to Article 94(3) EPC Dated Apr. 14, 2011 From the European Patent Office Re. Application No. 08700247.3.4Communication Pursuant to Article 94(3) EPC Dated Aug. 3, 2010 From the European Patent Office Re. Application No. 05758938.4.5Communication Pursuant to Article 94(3) EPC Dated Jun. 30, 2011 From the European Patent Office Re. Application No. 05758938.4.6Davies et al. "Oxidized Alkyl Phospholipids Are Specific, High Affinity Peroxisome Proliferator- Activated Receptor gamma ligands and Agonists", Jornal of Biological Chemistry, vol. 26 (19), p. 16015-16023, 2001.7Davies et al. "Oxidized Alkyl Phospholipids Are Specific, High Affinity Peroxisome Proliferator- Activated Receptor γ ligands and Agonists", Jornal of Biological Chemistry, vol. 26 (19), p. 16015-16023, 2001.8Examination Report and Notice of Acceptance of Complete Specification Dated Jul. 14, 2010 From the Intellectual Property Office of New Zealand Re.: Application No. 553147.9Examination Report Dated Apr. 21, 2009 From the Intellectual Property Office of New Zealand Re.: Application No. 553147.10Examination Report Dated Dec. 10, 2009 From the Intellectual Property Office of New Zealand Re.: Application No. 553147.11Examination Report Dated Jul. 22, 2011 From the Intellectual Property Office of New Zealand Re. Application No. 593529.12Examination Report Dated Jul. 29, 2011 From the Instituto Mexicano de la Propriedad Industrial Re. Application No. MX/a/2009/007422 and Its Translation Into English.13Examination Report Dated Jul. 7, 2010 From the Intellectual Property Office of New Zealand Re. Application No. 586503.14Examination Report Dated Jun. 22, 2011 From the Intellectual Property Office of New Zealand Re. Application No. 593529.15Examination Report Dated Jun. 23, 2011 From the Intellectual Property Office of New Zealand Re. Application No. 578947.16Examination Report Dated Oct. 27, 2010 From the Instituto Mexicano de la Propriedad Industrial Re. Application No. MX/a/2007/000361.17Examination Report Dated Sep. 16, 2010 From the Intellectual Property Office of New Zealand Re. Application No. 578947.18Examiner's Report Dated Aug. 31, 2010 From the Australian Government, IP Australia Re. Application No. 2007200090.19George et al. "Hyperimmunization of Apo-E-Deficient Mice Homologous Malondialdehyde Low-Density Lipoprotein Suppresses early Atherogenesis", Atherosclerosis 138, p. 147-152, 1998.20International Preliminary Report on Patentability Dated Oct. 29, 2009 From the International Bureau of WIPO Re.: Application No. PCT/IL2008/000013.21International Preliminary Report on Patentability Dated Sep. 15, 2008 From the International Preliminary Examining Authority Re.: Application No. PCT/IL05/00735.22International Search Report and the Written Opinion Dated Aug. 24, 2006 From the International Searching Authority Re.: Application No. PCT/IL05/00735.23International Search Report Dated Mar. 13, 2009 From the International Searching Authority Re.: Application No. PCT/IL08/00013.24Invitation Pursuant to Rule 62a(1) EPC Dated Jul. 8, 2010 From the European Patent Office Re. Application No. 08700247.3.25Itabe et al. "Oxidized Phosphatidylcholines That Modify Proteins", Jornal of Biological Chemistry, vol. 271 (52), p. 33208-33217, 1996.26Leitinger et al. "Structurally Similar Oxidized Phospholipids Differentially Regulate Endothelial Binding of Monocytes and Neutrophils", Proc. Natl. Acad. Sci. USA, 96(21): 12010-12015, 1999.27Notification to Grant Patent Right for Invention Dated Apr. 6, 2011 From the State Intellectual Property Office of the Peopl's Republic of China Re.: Application No. 200580029218.9 and Its Translation Into English.28Office Action Dated Jul. 21, 2011 From the Israeli Patent Office Re. Application No. 211795 and Its Translation Into English.29Office Action Dated Nov. 13, 2009 From the State Intellectual Property Office of the People's Republic of China Re.: Application No. 200580029218.9 and Translation of Proposed Claims Into English.30Office Action Dated Nov. 17, 2010 From the Israel Patent Office Re. Application No. 180628 and Its Translation Into English.31Official Action Dated May 27, 2009 From the Rospatent, Federal State Office , Federal Institution of Industrial Property of the Federal Office of Intellectual Property, Patents and Trademarks of the Russian Federation Re.: Application No. 2007105097 and Its Translation Into English.32Official Action Dated Oct. 29, 2009 From the Rospatent, Federal State Office , Federal Institution of Industrial Property of the Federal Office of Intellectual Property, Patents and Trademarks of the Russian Federation Re.: Application No. 2007105097 and Its Translation Into English.33Response Dated Aug. 10, 2011 to Communication Pursuant to Article 94(3) EPC of Jun. 30, 2011 From the European Patent Office Re. Application No. 05758938.4.34Response Dated Aug. 11, 2011 to Communication Pursuant to Article 94(3) EPC of Apr. 14, 2011 From the European Patent Office Re. Application No. 08700247.3.35Response Dated Aug. 16, 2011 to Examiner's Report of Aug. 31, 2010 From the Australian Government, IP Australia Re. Application No. 2007200090.36Response Dated Aug. 9, 2011 to Examination Report of Jun. 23, 2011 From the Intellectual Property Office of New Zealand Re. Application No. 578947.37Response Dated Dec. 27, 2010 to Notice of Reason for Rejection of Oct. 19, 2010 From the Japanese Patent Office Re.: Application No. 2007-519983.38Response Dated Feb. 1, 2011 to Examination Report of Jul. 7, 2010 From the Intellectual Property Office of New Zealand Re. Application No. 586503.39Response Dated Jan. 12, 2011 to Examination Report of Oct. 27, 2010 From the Instituto Mexicano de la Propriedad Industrial Re. Application No. MX/a/2007/000361.40Response Dated Jan. 13, 2010 to Office Action of Nov. 13, 2009 From the State Intellectual Property Office of the People's Republic of China Re.: Application No. 200580029218.9.41Response Dated Jan. 28, 2010 to Official Action of Oct. 29, 2009 From the Rospatent, Federal State Office , Federal Institution of Industrial Property of the Federal Office of Intellectual Property, Patents and Trademarks of the Russian Federation Re.: Application No. 2007105097.42Response Dated Mar. 1, 2010 to Official Action of Dec. 1, 2009 From the US Patent and Trademark Office Re.: U.S. Appl. No. 11/650,973.43Response Dated Mar. 17, 2011 to Office Action of Nov. 17, 2010 From the Israel Patent Office Re. Application No. 180628.44Response Dated May 17, 2010 to Examination Report of Dec. 10, 2009 From the Intellectual Property Office of New Zealand Re.: Application No. 553147.45Response Dated May 26, 2011 to Examination Report of Sep. 16, 2010 From the Intellectual Property Office of New Zealand Re. Application No. 578947.46Response Dated Nov. 28, 2010 to Communication Pursuant to Article 94(3) EPC of Aug. 3, 2010 From the European Patent Office Re. Application No. 05758938.4.47Response Dated Oct. 2, 2011 to Examination Report of Jul. 29, 2011 From the Instituto Mexicano de la Propriedad Industrial Re. Application No. MX/a/2009/007422.48Response Dated Sep. 7, 2010 to Invitation Pursuant to Rule 62a(1) EPC of Jul. 8, 2010 From the European Patent Office Re. Application No. 08700247.3.49Revised Response Dated Jun. 20, 2010 to Examination Report of Dec. 10, 2009 From the Intellectual Property Office of New Zealand Re.: Application No. 553147.50Subbanagounder et al. "Determinants of Bioactivity of Oxydized Phospholipids: Specific Oxidized Fatty Acyl Groups at the SN-2 Position," Arteriosclerosis Thromb. Vasc. Biol., p. 2248-2254, 2000.51Subbanagounder et al. "Evidence That Phospholipid Oxidation Products and/or Platelet-Activating Factor Play an Important Role in Early Atherogenesis: In Vitro and In Vivo Inhibition by Web 2086", Circulation Research, 85: 311-318, 1999.52Supplementary Partial European Search Report and the European Search Opinion Dated Nov. 30, 2009 From the European Patent Office Re.: Application No. 05758938.4.53Supplementary Partial European Search Report Dated Apr. 4, 2011 From the European Patent Office Re. Application No. 08700247.3.54Tokumura et al. "Cardiovascular Effects of Lysophophatidic Acid and Its Structural Analogs in Rats", The Journal of Pharmacology and Experimental Therapeutics, 219(1): 219-222, 1981.55Translation of Notice of Reason for Rejection Dated Feb. 26, 2010 From the Japanese Patent Office Re.: Application No. 2007-519983.56Translation of Notice of Reason for Rejection Dated Oct. 19, 2010 From the Japanese Patent Office Re.: Application No. 2007-519983.57Translation of Office Action Dated May 8, 2009 From the State Intellectual Property Office of the Peopl's Republic of China Re.: Application No. 200580029218.9.58Translation of Office Action Dated Sep. 5, 2011 From the State Intellectual Property Office of the People's Republic of China Re. Application No. 201010128184.1.59Watson et al. "Structural Identification by Mass Spectrometry of Oxidized Phospholipids in Minimally Oxidized Low Density Lipoprotein That Induce Monocyte/Endothelial Interactions and Evidence for Their Presence in Vivo".60Written Opinion Dated Mar. 13, 2009 From the International Searching Authority Re.: Application No. PCT/IL08/00013.Referenced byCiting PatentFiling datePublication dateApplicantTitleUS8501715Apr 13, 2011Aug 6, 2013Vascular Biogenics Ltd.Oxidized lipids and uses thereof in the treatment of inflammatory diseases and disordersUS8563534Mar 27, 2012Oct 22, 2013Vascular Biogenics Ltd.Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosisUS8569529Nov 9, 2012Oct 29, 2013Vascular Biogenics Ltd.High-purity phospholipidsClassifications U.S. Classification554/78, 560/186, 554/150, 558/103International ClassificationC07F9/02Cooperative ClassificationC07C45/27, C07F9/106, C07F9/091, C07C29/48, C07C51/16, C07B41/00, C07C67/39, C07C67/28, C07C67/08, C07C45/29, C07C51/29, C07F9/10, C07C41/26European ClassificationC07F9/10YLegal EventsDateCodeEventDescriptionJun 19, 2012CCCertificate of correctionApr 30, 2012ASAssignmentEffective date: 20070109Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:HALPERIN, GIDEON;KOVALEVSKI-ISHAI, ETI;REEL/FRAME:028126/0738Owner name: VASCULAR BIOGENICS LTD., ISRAELRotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google