Source: http://www.google.com/patents/US8111400?dq=4200770
Timestamp: 2014-07-31 09:50:11
Document Index: 337743663

Matched Legal Cases: ['art4', 'art4', 'Application No. 02808314', 'Application No. 02808314', 'Application No. 02808314', 'Application No. 2004', 'Application No. 2004', 'Application No. 2', 'Application No. 2004']

Patent US8111400 - Surface plasmon resonance sensor - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign in<nobr>Advanced Patent Search</nobr>PatentsAn SPR sensor comprising a thin conducting layer comprising at least one conductive element formed on a surface of a transparent substrate, a light source that illuminates an interface between the conducting layer and the substrate, a photosensitive surface that generates signals from light reflected...http://www.google.com/patents/US8111400?utm_source=gb-gplus-sharePatent US8111400 - Surface plasmon resonance sensorAdvanced Patent SearchPublication numberUS8111400 B2Publication typeGrantApplication numberUS 13/181,547Publication dateFeb 7, 2012Filing dateJul 13, 2011Priority dateDec 25, 2002Also published asCA2511934A1, CA2511934C, DE60232689D1, EP1581800A1, EP1581800B1, US7443507, US7586616, US7999942, US8363223, US8743369, US20060072113, US20080198384, US20090296095, US20110267622, US20120113428, US20130196448, US20130330838, WO2004059301A1Publication number13181547, 181547, US 8111400 B2, US 8111400B2, US-B2-8111400, US8111400 B2, US8111400B2InventorsBoaz Ran, Ariel G. Notcovich, Ariel Lipson, Shay Nimri, Stephen G. Lipson, Doron LipsonOriginal AssigneeBio-Rad Laboratories Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (63), Non-Patent Citations (48), Referenced by (6), Classifications (8) External Links: USPTO, USPTO Assignment, EspacenetSurface plasmon resonance sensorUS 8111400 B2Abstract An SPR sensor comprising a thin conducting layer comprising at least one conductive element formed on a surface of a transparent substrate, a light source that illuminates an interface between the conducting layer and the substrate, a photosensitive surface that generates signals from light reflected from the interface, a flow cell formed with at least one flow channel having a lumen defined by a wall formed from an elastic material and from a region of the conducting layer, and at least one hollow fluid-providing flow control apparatus having a lumen and an orifice communicating with its lumen. Fluid flow is enabled between the flow channel and the lumen of the flow control apparatus by forcing an end of the flow control apparatus through the elastic material so that the orifice communicates with the flow channel lumen.
RELATED APPLICATIONS This application is a divisional of U.S. patent application Ser. No. 12/535,707 filed Aug. 5, 2009, which is a continuation of U.S. patent application Ser. No. 12/149,158 filed Apr. 28, 2008, now U.S. Pat. No. 7,586,616, which is divisional of U.S. patent application Ser. No. 10/540,940 filed Jun. 23, 2005, now U.S. Pat. No. 7,443,507, which is a National Phase of PCT Patent Application No. PCT/IL2002/001037 filed Dec. 25, 2002. The contents of all of the above applications are incorporated herein by reference.
BACKGROUND OF THE INVENTION SPR sensors generate optical signals responsive to the dielectric constant and/or thickness, hereinafter referred to collectively as �optical properties�, of regions of a layer, hereinafter referred to as a �probe layer�, of material contiguous with a thin layer of conducting material. The thin conductive layer, hereinafter an �SPR conductor�, typically has a thickness less than about 100 nm and is generally formed from a metal, usually silver or gold, on a surface of a transparent substrate such as glass. The surface on which the SPR conductor is formed is hereinafter referred to as a �sensor surface�.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS4844613Nov 2, 1987Jul 4, 1989Stc PlcOptical surface plasmon sensor deviceUS4889427 *Apr 11, 1988Dec 26, 1989Nederlandse Organisatie Voor Toegepastnatuurwetenschappelijk Onderzoek TnoMethod and apparatus for detecting low concentrations of (bio) chemical components present in a test medium using surface plasmon resonanceUS5047213Jan 18, 1989Sep 10, 1991Amersham International PlcBiological sensorsUS5313264Nov 9, 1989May 17, 1994Pharmacia Biosensor AbOptical biosensor systemUS5341215May 28, 1992Aug 23, 1994Hewlett-Packard CompanyMethod and apparatus for detecting the presence and/or concentration of biomoleculesUS5633724Aug 29, 1995May 27, 1997Hewlett-Packard CompanyEvanescent scanning of biochemical arrayUS5694930Aug 19, 1993Dec 9, 1997Yoon-Ok KimDevice for qualitative and/or quantative analysis of a sampleUS5770462May 27, 1994Jun 23, 1998Fisons PlcAnalytical apparatusUS5812272Jan 30, 1997Sep 22, 1998Hewlett-Packard CompanyApparatus for analyzing target chemicalsUS5907408Apr 30, 1997May 25, 1999Fuji Photo Film Co., Ltd.Surface plasmon sensorUS5917607 *Apr 24, 1997Jun 29, 1999Fuji Photo Film Co., Ltd.Surface plasmon sensor for multiple channel analysisUS5917608Apr 29, 1998Jun 29, 1999Fuji Photo Film Co., Ltd.Surface plasmon sensorUS5926284Apr 29, 1998Jul 20, 1999Fuji Photo Film Co., Ltd.Surface plasmon sensorUS6008893Mar 22, 1999Dec 28, 1999Biacore AbReversible-flow conduit systemUS6268125Nov 5, 1997Jul 31, 2001The Secretary Of State For Defence In Her Brittanic Majesty's Government Of The United Kingdom Of Great Britain And Northern IrelandSurface plasmon resonance device; for the detction of preferential particles in sampleUS6326612Oct 12, 1999Dec 4, 2001Texas Instruments IncorporatedSystem and method for optical sensing utilizing a portable, detachable sensor cartridgeUS6404492Oct 30, 1996Jun 11, 2002Kyoto Daiichi Kagaku Co., Ltd.Light source apparatus and measurement methodUS6424418May 26, 1999Jul 23, 2002Canon Kabushiki KaishaSurface plasmon resonance sensor apparatus using surface emitting laserUS6570657Apr 6, 1999May 27, 2003Institut Fuer Physikalische Hochtechnolgolie E.V.Arrangement for surface plasmon resonance spectroscopyUS6600563Dec 14, 1998Jul 29, 2003Applera CorporationOptical resonance analysis systemUS6692974Nov 5, 1997Feb 17, 2004The Secretary Of State For Defence In Her Brittanic Majesty's Government Of The United Kingdom Of Great Britain And Northern IrelandSurface plasmon resonance apparatus for detecting preferential cells, nucleic acids or proteins in sampleUS6738141Jan 28, 2000May 18, 2004Vir A/SSurface plasmon resonance sensorUS6801317May 9, 2001Oct 5, 2004Jandratex GmbhPlasmon resonance sensorUS6873417Apr 28, 2003Mar 29, 2005Applera CorporationOptical resonance analysis systemUS7251085Jul 28, 2006Jul 31, 2007Applera CorporationOptical resonance analysis systemUS7535570Oct 7, 2005May 19, 2009Fujifilm CorporationOne dimensional measuring unit having a dielectric blockUS20020117517Nov 16, 2001Aug 29, 2002Fluidigm CorporationMicrofluidic devices for introducing and dispensing fluids from microfluidic systemsUS20030076501May 9, 2001Apr 24, 2003Andreas HofmannPlasmon resonance sensorUS20060072113Dec 25, 2002Apr 6, 2006Boaz RanSurface plasmon resonance sensorUS20080198384Apr 28, 2008Aug 21, 2008Bio-Rad Haifa Ltd.Surface plasmon resonance sensorUS20090296095Aug 5, 2009Dec 3, 2009Bio-Rad Laboratories Inc.Surface plasmon resonance sensorAU742417B2 Title not availableEP0305109A1Aug 18, 1988Mar 1, 1989AMERSHAM INTERNATIONAL plcBiological sensorsEP0341928A1May 5, 1989Nov 15, 1989AMERSHAM INTERNATIONAL plcImprovements relating to surface plasmon resonance sensorsEP0442921A1Nov 9, 1989Aug 28, 1991Pharmacia Biosensor AbOptical biosensor system.EP0867697A1Oct 30, 1996Sep 30, 1998Kyoto Dai-ichi Kagaku Co., Ltd.Light source apparatus and measurement methodEP0938661A1Nov 5, 1997Sep 1, 1999The Secretary Of State For DefenceAnalytical apparatusEP1068511A1Apr 6, 1999Jan 17, 2001Analytik Jena GmbH, Analysenmessger�te und LaboreinrichtungenArrangement for surface plasmon resonance spectroscopyJP3064313B2 Title not availableJP3294605B2 Title not availableJP2001504582A Title not availableJP2001526386A Title not availableJP2002540405A Title not availableJPH1137929A Title not availableJPH1144647A Title not availableJPH01224647A Title not availableJPH03503806A Title not availableJPH09126888A Title not availableJPH09292332A Title not availableJPH09292333A Title not availableWO1990005317A1Nov 9, 1989May 17, 1990Pharmacia AbOptical interface meansWO1990009576A1Jan 29, 1990Aug 23, 1990Plessey OverseasA method for detecting optical phase changes during biosensor operation, biosensing apparatus and a biosensor adapted for use in the sameWO1992019984A1Apr 29, 1992Nov 12, 1992Valtion TeknillinenApparatus for locating an object, and light transmitterWO1998022808A1Nov 5, 1997May 28, 1998Secr DefenceAnalytical apparatusWO1998057149A1May 7, 1998Dec 17, 1998Beloglazov Anatoly AnatolievicA method of examining biological, biochemical, and chemical characteristics of a medium and apparatus for its embodimentWO1999030135A1Dec 14, 1998Jun 17, 1999Dar BahattOptical resonance analysis systemWO2000022419A1Apr 6, 1999Apr 20, 2000Analytik Jena Gmbh AnalysenmesArrangement for surface plasmon resonance spectroscopyWO2001020295A2Sep 12, 2000Mar 22, 2001Lipson StephenPlasmon resonance phase imagingWO2001086262A1May 9, 2001Nov 15, 2001Hofmann AndreasPlasmon resonance sensorWO2002036485A1Nov 1, 2001May 10, 2002Biacore AbValve integrally associated with microfluidic liquid transport assemblyWO2002055993A2Jan 11, 2002Jul 18, 2002Univ BostonUse of electrostatic fields to enhance surface plasmon resonance spectroscopyWO2002063349A2Feb 1, 2002Aug 15, 2002Res Int IncEnhanced waveguide and methodWO2004059301A1Dec 25, 2002Jul 15, 2004Proteoptics LtdSurface plasmon resonance sensor* Cited by examinerNon-Patent CitationsReference1"An Introduction to SPR-Surface Plasmon Resonance", 2 P., 2002. http://www.uksaf.org/tech/spr.html.2"BlAcore Surface Plasmon Resonance (SPR)", 3 P., 2002. http://www.astbury.leeds.ac.uk/Facil/spr.htm.3"Refractive Index Sensing With Surface Plasmon Resonance: The Kretschmann Geometry", Spreeta Technology Overview, 2 P., 2001.4"An Introduction to SPR�Surface Plasmon Resonance", 2 P., 2002. http://www.uksaf.org/tech/spr.html.5Berger et al. "Surface Plasmon Propagation Near an Index Step", MESA Institute, Applied Optics Group, University of Twente, p. 1-10, 2002, http:/lps.ens.fr/~berger/articles/art4/OptComm/htm.6Berger et al. "Surface Plasmon Resonance Multisensing", Analytical Chemistry, 70(4): 703-706, 1998.7Berger et al. "Surface Plasmon Propagation Near an Index Step", MESA Institute, Applied Optics Group, University of Twente, p. 1-10, 2002, http:/lps.ens.fr/�berger/articles/art4/OptComm/htm.8Communication Pursuant to Article 96(2) EPC Dated Nov. 2, 2007 From the European Patent Office Re.: Application No. 02808314.5.9Communication Pursuant to Article 96(2) EPC Dated Nov. 30, 2006 From the European Patent Office Re.: Application No. 02808314.5.10Communication Relating to the Result of the Partial International Search Report Dated Oct. 23, 2003 From the International Searching Authority Re.: Application No. PCT/IL02/01037.11Grigorenko et al. "Dark-Field Surface Plasmon Resonance Microscopy", Optics Communications, 174: 151-155, 2000.12Grigorenko et al. "Phase Jumps and Interferometric Surface Plasmon Resonance Imaging", Applied Physics Letters, 75(25): 3917-3919, 1999.13Herminghaus et al. "Phase Contrast Surface Mode Resonance Microscopy", Quantum Electronics, 112: 16-20, 1994.14Homola et al. "Surface Plasmon Resonance Sensors: Review", Sensors and Actuators, B 54: 3-15, 1999.15International Preliminary Examination Report Dated Mar. 24, 2005 From the European Patent Office Re.: Application No. PCT/IL02/01037.16International Search Report Dated Jan. 14, 2004 From the International Searching Authority Re.: Application No. 02808314.5.17Jordan et al. "Surface Plasmon Resonance Imaging Measurements of Electrostatic Biopolymer Adsorption Onto Chemically Modified Gold Surfaces", Analytical Chemistry, 69(7): 1449-1456, 1997.18Kabashin et al. "Interferometer Based on a Surface-Plasmon Resonance for Sensor Applications", Quantum Electronics, 27(7): 653-654, 1997.19Kabashin et al. "Phase-Polarisation Contrast for Surface Plasmon Resonance Biosensors", Biosensors & Bioelectronics, 13: 1263-1269, 1998.20Kabashin et al. "Surface Plasmon Resonance Bio-and Chemical-Sensors With Phase-Polarisation Contrast", Sensors and Actuators, B 54: 51-56, 1999.21Kabashin et al. "Surface Plasmon Resonance Interferometer for Bio-and Chemical-Sensors", Optics Comminications, 150: 5-8, 1998.22Kochergin et al. "Phase Properties of a Surface-Plasmon Resonance From the Viewpoint of Sensor Applications", Quantum Electronics, vol. 28(5): 444-448, 1998.23Kochergin et al. "Visualisation of the Angular Dependence of the Reflected-Radiation Phase Under Conditions of a Surface-Plasmon Resonance and its Sensor Applications", Quantum Electronics, 28(9): 835-839, 1998.24Lipson "Experiment Procedure", ProteOptics, Haifa, IL, 2 P. 2002.25L�f�s et al. "Bioanalysis With Surface Plasmon Resonance", Sensors and Actuators B Chemical, 5(1/4): 79-84, 1991. p. 79, col. 2, Par.2-p. 81, col. 1, Par.2.26Marszalec "Modelling and Simulation of an Angular-Scan LED Array-Based Range Imaging Sensor", Proceedings of the 1993 IEEE/RSJ International Conference on Intelligent Robots and Systems, Yokohama, JP, p. 1837-1844, 1993.27Marszalec et al. "A LED-Array-Based Range-Imaging Sensor for Fast Three-Dimensional Shape Measurments", Sensors and Actuators A, 46-47: 501-505, 1995.28Marszalec et al. "A Photoelectric Range Scanner Using an Array of LED Chips", Proceedings of the 1992 IEEE International Conference on Robots and Automation, Nice, FR, p. 593-598, 1992.29Nikitin et al. "Surface Plasmon Resonance Interferometry for Biological and Chemical Sensing", Sensors and Actuators, B 54: 43-50, 1999.30Nikitin et al. "Surface Plasmon Resonance Interferometry for Micro-Array Biosensing", Eurosensors XIII, The 13th European Conference on Solid-State Transducers, The Hague, NL, Optical Techniques in (Bio)Chemical Systems, 5A4: 235-238, 1999.31Notcovich et al. "Surface Plasmon Resonance Phase Imaging", Applied Physics Letters, 76(13): 1665-1667, 2000.32Notice of Allowance Dated Apr. 18, 2011 From the US Patent and Trademark Office Re.: U.S. Appl. No. 12/535,707.33Notice of Allowance Dated Jan. 29, 2008 From the US Patent and Trademark Office Re.: U.S. Appl. No. 10/540,940.34Notice of Allowance Dated Jun. 4, 2008 From the US Patent and Trademark Office Re.: U.S. Appl. No. 10/540,940.35Notice of Allowance Dated May 1, 2009 From the US Patent and Trademark Office Re.: U.S. Appl. No. 12/149,158.36Notification of Reasons of Rejection Dated Jan. 29, 2009 From the Japanese Patent Office Re.: Application No. 2004-563535 and Its Translation Into English.37Official Action Dated Aug. 13, 2010 From the US Patent and Trademark Office Re.: U.S. Appl. No. 12/535,707.38Official Action Dated Jun. 15, 2007 From the US Patent and Trademark Office Re.: U.S. Appl. No. 10/540,940.39Official Action Dated Nov. 24, 2010 From the US Patent and Trademark Office Re.: U.S. Appl. No. 12/535,707.40Official Action Dated Nov. 30, 2007 From the Japanese Patent Office Re.: Application No. 2004-563535 and Its Translation Into English.41Official Action Dated Sep. 17, 2008 From the US Patent and Trademark Office Re.: U.S. Appl. No. 12/149,158.42Requisition by the Examiner Dated Oct. 5, 2009 From the Canadian Intellectual Property Office Re.: Application No. 2,511,934.43Response Dated Feb. 24, 2011 to Official Action of Nov. 24, 2010 From the US Patent and Trademark Office Re.: U.S. Appl. No. 12/535,707.44Response Dated Sep. 7, 2010 to Official Action of Aug. 13, 2010 From the US Patent and Trademark Office Re.: U.S. Appl. No. 12/535,707.45Teng et al. "Simple Reflection Technique for Measuring the Electro-Optic Coefficient of Poled Polymers", Applied Physics Letters, 56 (18): 1734-1736, 1990.46Totzeck et al. "Phase-Shifting Polarization Interferometry for Microstructure Linewidth Measurement", Optic Letters, 24(5): 294-296, 1999.47Translation of Notice of Reason(s) for Rejection Dated Nov. 30, 2007 From the Japanese Patent Office Re.: Application No. 2004-563535.48Written Opinion Dated Nov. 23, 2004 From the International Searching Authority Re.: Application No. PCT/IL02/01037.Referenced byCiting PatentFiling datePublication dateApplicantTitleUS8363223 *Jan 12, 2012Jan 29, 2013Bio-Rad Laboratories Inc.Surface plasmon resonance sensorUS8368897 *Aug 21, 2009Feb 5, 2013Ciencia, Inc.Versatile surface plasmon resonance analyzer with an integral surface plasmon resonance enhanced fluorescence modeUS8526001 *Jan 28, 2013Sep 3, 2013Ciencia, Inc.Versatile surface plasmon resonance analyzer with an integral surface plasmon resonance enhanced fluorescence modeUS8743369Aug 14, 2013Jun 3, 2014Bio-Rad Laboratories Inc.Surface plasmon resonance sensorUS20100078575 *Aug 21, 2009Apr 1, 2010Reilly Michael TVersatile Surface Plasmon Resonance Analyzer with an Integral Surface Plasmon Resonance Enhanced Fluorescence ModeUS20120113428 *Jan 12, 2012May 10, 2012Bio-Rad Laboratories Inc.Surface plasmon resonance sensor* Cited by examinerClassifications U.S. Classification356/445International ClassificationG01N21/55, G01N21/00, G01N21/05Cooperative ClassificationG01N2021/058, G01N21/55, G01N21/553European ClassificationG01N21/55B2RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google