Source: http://www.google.com/patents/US7828787?ie=ISO-8859-1&dq=1886562
Timestamp: 2015-05-04 06:28:29
Document Index: 377283380

Matched Legal Cases: ['art 1', 'art 1', 'art 1', 'art 1', 'art 1', 'art 1', 'art 16', 'art 1', 'art 16', 'art 17', 'art 40', 'art 40', 'art 40', 'art 40', 'art 20', 'art 40', 'art 1', 'art 1', 'art 16', 'art 17', 'art 17', 'art 16', 'art 20', 'art 1', 'art 20', 'art 1']

Patent US7828787 - Connector for packaging containing medical fluids and packaging for medical ... - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsThe disclosure relates to a connector for packaging containing medical fluids, in particular infusion or transfusion bags, including a tubular connection part for receiving a spike for the withdrawal of fluid, and having a lower opening on the packaging side and an upper opening on the connection side....http://www.google.com/patents/US7828787?utm_source=gb-gplus-sharePatent US7828787 - Connector for packaging containing medical fluids and packaging for medical fluidsAdvanced Patent SearchPublication numberUS7828787 B2Publication typeGrantApplication numberUS 10/514,817PCT numberPCT/EP2003/001847Publication dateNov 9, 2010Filing dateFeb 24, 2003Priority dateMay 27, 2002Fee statusPaidAlso published asCA2487551A1, CA2487551C, CN1655750A, CN100398084C, DE10223560A1, DE10223560B4, DE50312773D1, EP1507502A1, EP1507502B1, EP2191807A2, EP2191807A3, US8118802, US20050215943, US20110022024, WO2003099191A1Publication number10514817, 514817, PCT/2003/1847, PCT/EP/2003/001847, PCT/EP/2003/01847, PCT/EP/3/001847, PCT/EP/3/01847, PCT/EP2003/001847, PCT/EP2003/01847, PCT/EP2003001847, PCT/EP200301847, PCT/EP3/001847, PCT/EP3/01847, PCT/EP3001847, PCT/EP301847, US 7828787 B2, US 7828787B2, US-B2-7828787, US7828787 B2, US7828787B2InventorsTorsten Brandenburger, Ismael RahimyOriginal AssigneeFresenius Kabi Deutschland GmbhExport CitationBiBTeX, EndNote, RefManPatent Citations (16), Non-Patent Citations (2), Referenced by (4), Classifications (20), Legal Events (3) External Links: USPTO, USPTO Assignment, EspacenetConnector for packaging containing medical fluids and packaging for medical fluids
US 7828787 B2Abstract
a tubular connection part for receiving a spike for the extraction of the fluid, the connection part comprising a lower section and an upper section, said parts being fixed in a snap-in manner, and a package-side lower opening and a connection-side upper opening;
a break-off sealing part that seals the connection-side opening of the connection part; and
a self-sealing membrane disposed in the connection part, which can be pierced by the spike for the extraction of the fluid, said self-sealing membrane comprising:
an inner dish-shaped section having a top surface with a central recessed planar portion and an annular wall portion having a first inner face extending up at a first obtuse angle from the planar portion, which can be penetrated by a tubular extraction device;
an inner circular section having a second inner face extending up from the first inner face at a second obtuse angle relative to the planar portion, wherein the second obtuse angle is greater than the first obtuse angle; and
an outer circular section for the fixing of the membrane at the extraction point, said outer circular section having a substantially T-shape configuration clamped with elastic deformation of the membrane between the lower section and the upper section during use,
wherein the inner circular section is connected to the stem of the T-shape of the outer circular section,
wherein the inner circular section and the inner dish-shaped section together form a trough-shaped recess, and
wherein the inner circular section of the membrane surrounds the spike in a sealed manner during penetration of the dish-shaped portion.
14. A self-sealing membrane for use in extraction points for containers for medical fluids, comprising:
an outer circular section for the fixing of the membrane at the extraction point, said outer circular section having a substantially T-shape configuration configured to be clamped with elastic deformation of the membrane between a lower section and an upper section of a connection part,
wherein the inner circular section is connected to the stem of the T-shape on of the outer circular section,
wherein the inner circular section surrounds the tubular extraction device in a sealed manner during the penetration of the dish-shaped section.
19. The connector according to claim 1, wherein the inner dish-shaped section has a planar bottom that extends lower that the bottom of the outer circular section. Description
This is the U.S. national phase of International Application No. PCT/EP03/01847 filed Feb. 24, 2003, the entire disclosure of which is incorporated herein by reference.
The disclosure relates to a connector for packaging containing medical fluids, in particular infusion or transfusion bags, which serves to inject or extract a fluid from the bag. Moreover, the disclosure relates to packaging for medical fluids, in particular an infusion or transfusion bag, with such a connector.
WO 96/23545 describes an infusion bag with an injection part and an extraction part. The injection part serves to feed a drug by means of an injection syringe. It comprises a tubular connection part, which is sealed by a protective cap designed as a break-off part. A self-sealing septum sits in the opening area of the connection part, whilst a membrane capable of being pierced is arranged in the connection part, so that the septum does not come into contact with the solution before the use of the infusion bag. The extraction part serves to extract the solution by means of a spike. The extraction part does not have a self-sealing septum, but otherwise the structure is similar to that of the injection part.
A further drawback is that the connection between the spike and the extraction part is not secured against slipping out. When the bag is hanging on the stand, there is the risk of the connection of the spike and the extraction part being separated due to unintentional tugging on the flexible-tube line.
Accordingly, the disclosure provides a connector for packages containing medical fluids, including a tubular connection part for receiving a spike for the extraction of the fluid, the connection part having upper and lower openings, a break-off sealing part, a self-sealing membrane that can be pierced by the spike for the extraction of the fluid and having a circular upper portion, which transforms into a dish-shaped lower portion to form a trough-shaped recess, wherein a portion of the membrane sealingly surrounds the spike when the spike pierces the dish-shaped portion.
It is advantageous that the self-sealing membrane has a circular portion, which is continuous with a dish-shaped portion, whereby the circular portion of the membrane surrounds the spike in a sealed manner when it pierces the dish-shaped portion.
The special formation of the membrane with the circular and dish-shaped portion ensures that the spike is guided reliably when it pierces the membrane and guarantees that the membrane is again reliably sealed after withdrawal of the spike even in the presence of relatively high internal pressure in the packaging. It has been shown in tests that the special formation of the membrane is decisive for immediate re-sealing, whereby the sealing of the membrane is further enhanced with increasing pressure in the packaging. The reliable sealing can be traced back not to the volume of material, but to the special geometry of the membrane.
In a preferred embodiment of the connector according to the invention, the material of the dish-shaped portion of the membrane is weakened, so that the membrane can be particularly easily pierced by the spike. The membrane is preferably pre-slit in the form of a cross. It can also be pre-slit in the form of a star or the like or only be provided with a simple slit.
In a particularly preferred embodiment, the tubular connection part of the connector consists of a lower and an upper section, whereby the sections are fixed in a snap-in manner. The self-sealing membrane is preferably held clamped with elastic deformation between the lower and upper section. Consequently, the fitting of the connector can be carried out in a straightforward manner by pressing together the individual parts. It is however also possible for the individual parts to be welded and/or glued together.
A further particularly preferred embodiment makes provision such that an outer portion, which is clamped between the upper and lower sections, is continuous with the circular portion of the membrane.
In order to prevent the self-sealing membrane in the tubular connection part from coming into contact with the solution contained in the infusion or transfusion bag prior to use, a second membrane capable of being pierced is preferably arranged beneath the self-sealing membrane thereby forming an intermediate space. The second membrane is expediently a one-piece component of the tubular connection part.
The lower part of the connection part also preferably has an arrow pointing upwards, which is designed as a raised structure, preferably in a recessed grip. The upward-pointing arrow of the lower part also permits the connector to be unequivocally assigned as the extraction part after breaking-off the sealing part.
Connector 20 designed as an extraction part for packages containing medical fluids, in particular infusion or transfusion bags, has a tubular connection part 1, which includes a package-side lower section 2 and a connection-side upper section 3. Tubular connection part 1 therefore has an upper and a lower opening 1 a, 1 b. Connector 20 is an injection-molded part made of polypropylene.
Lower section 2 of tubular connection part 1 has a lower cylindrical portion 4, which is continuous with an upper sleeve-shaped portion 5. Cylindrical portion 4 of lower section 2 can be inserted into a connection socket of a film bag and can be welded or glued to the socket or be directly welded into the film bag without a socket. Cylindrical portion 4 is sealed at its upper end with a membrane 6 capable of being pierced, said membrane being a single-piece component of lower section 2. The injected membrane 6 is curved downwards. Alternatively, however, the membrane 6 can also be curved upwards.
A self-sealing membrane 10 made of an elastic material, which is also referred to as a septum, is held clamped with elastic deformation between the lower and upper section 2, 3 of tubular connection part 1. Self-sealing membrane 10 has an outer portion 11, which is clamped between lower and upper sections 2, 3 of circular connection part 1. Outer portion 11 is followed by an upper circular portion 12, which is continuous with a lower dish-shaped portion 14 thereby forming a trough-shaped recess 13 at the upper side of membrane 10. Dish-shaped portion 14 is pre-slit in the form of a cross or a star in center 15, so that the elastic material is weakened, but is not severed.
Upper section 3 of tubular connection part 1 is followed, via a circular rupture zone 31, by a cap-shaped sealing part 16, which seals upper opening 1 a of connection part 1. Sealing part 16 is continuous with a flat grip part 17, which is provided with a recess 18 in the shape of an arrow 19 pointing upwards. It can immediately be recognized from the direction of arrow 19 that connector 20 is not injection part 40, but rather the extraction part.
The side view of connector 20 of FIG. 1 is shown in FIG. 2. FIG. 2 shows an infusion bag 21 filled with infusion solution, which has connector 20 for the extraction of the infusion solution and a further connector 40 for the injection of a solution into infusion bag 21.
Infusion bag 21 comprises two film layers 24, which are welded together at lower and upper edge 25, 26 and also at longitudinal edges 27, 28. Two connections sockets 29, 30 are welded into upper edge 26 of the infusion bag. The tubular connection pieces of injection and extraction part 40, 20 are inserted into connection sockets 30, 29, respectively and connected with the sockets during sterilization. The tubular connection pieces of the originality seals can however also be molded onto an insert that is round or designed in the manner of a boat, said insert being welded in between the two film layers 24.
FIG. 3 shows injection part 40 of film bag 21 in a sectional representation. Injection part 40 has a similar structure to extraction part 20. The parts corresponding to one another are therefore provided with the same reference numbers. Injection part 40 has a tubular connection part 1′, which consists of a lower and an upper section 2′, 3′. The two sections 2′, 3′ are fixed in a snap-in manner with the interposition of a self-sealing membrane 10′, whereby a projecting shoulder 9′ of lower section 2′ extending from wall 4′ engages in a groove 8′ of upper section 3′. Flat membrane 6′, which can alternatively be curved, is injected into lower section 2′.
Upper section 3′ of tubular connection part 1′ is again followed, via a circular rupture zone 31′, by a cap-shaped break-off part 16′, which is continuous with a flat grip part 17′. An arrow 19′ pointing downwards is designed as a recess in grip part 17′. Arrows 23′ pointing downwards to indicate the flow direction are located on the outer wall of upper section 3′ again inside recessed grips 21′, formed by projecting webs 22′.
For the extraction of infusion solution, break-off part 16 of extraction part 20 is broken off by turning or breaking the same, so that self-sealing membrane 10 is laid bare. The spike of a known transfer system is pushed into tubular connection part 1 of extraction part 20, as a result of which pre-slit membrane 10 is pierced and membrane 6 curved downwards is penetrated. Trough-shaped recess 13 serves as a guide for the spike. The spike is sealed by circular portion 12 of membrane 10. On account of the special formation of injected membrane 6, the spike is held firmly in tubular connection part 1.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS3136440Jun 25, 1963Jun 9, 1964Becton Dickinson CoSelf sealing pierceable stopper for sealed containersUS3900028Feb 26, 1974Aug 19, 1975American Hospital Supply CorpInjection site for sterile medical liquid containerUS4516977 *Feb 16, 1984May 14, 1985Fresenius, AgStorage bagUS5088995Jun 22, 1990Feb 18, 1992Baxter International Inc.Port and closure assembly including a resealing injection site for a containerUS5259843 *Nov 14, 1991Nov 9, 1993Kawasumi Laboratories Inc.Medical connector for attaching to liquid introducing tubeUS5896989 *Feb 20, 1998Apr 27, 1999Bracco Research UsaFlexible medical container packagingUS6039718 *Feb 9, 1999Mar 21, 2000Bracco Research UsaMultiple use universal connectorUS6893428 *Nov 20, 2001May 17, 2005Benjamin R. WillemstynOver-wrap bag enclosure for sterile connectorsDE1498600B1Mar 18, 1964Mar 26, 1970Becton Dickinson CoSelbstabdichtender, durchstechbarer St�psel aus elastomerem MaterialDE3543825A1Dec 12, 1985Jun 26, 1986Schiwa GmbhClosure piece for infusion containersDE10030474C1 *Jun 21, 2000Feb 21, 2002Fresenius Kabi De GmbhConnector for infusion or transfusion bag comprises cylindrical connection piece closed by self-sealing septum and with catches positioned diametrically opposite each which are biased outwards at base by flexible stripsDE19728775A1Jul 5, 1997Jan 21, 1999Fresenius AgSecurity seal for packs containing medical fluids, especially infusion or transfusion bagsDE69416696T2Nov 18, 1994Sep 16, 1999Abbott LabWiederverschliessbarer verschluss f�r fl�ssigkeits�ffnungEP0737058B1Nov 18, 1994Feb 24, 1999Abbott LaboratoriesFluid port reseal memberWO1995017873A1Nov 18, 1994Jul 6, 1995Abbott LabFluid port reseal memberWO1996023545A1Feb 2, 1996Aug 8, 1996Risto HaemaelaeinenConnecting element* Cited by examinerNon-Patent CitationsReference1 *English machine translation of DE 100 30 474 C1.2International Preliminary Examination Report in PCT/EP03/01847 dated Mar. 23, 2004.* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS8034041Mar 25, 2009Oct 11, 2011Hospira, Inc.Port closure system for intravenous fluid containerUS8034042Apr 2, 2009Oct 11, 2011Hospira, Inc.Port closure system for intravenous fluid containerUS8136330Apr 30, 2009Mar 20, 2012Hospira, Inc.Medical fluid containerUS8211081Aug 12, 2005Jul 3, 2012Fresenius Kabi Deutschland GmbhClosing cap for containers filled with medical liquidsClassifications U.S. Classification604/411, 206/486, 604/408, 383/109, 604/409, 383/107, 206/219, 604/410International ClassificationA61J1/10, A61J1/20, A61M25/18, A61M5/32, A61J1/05, B65D33/38Cooperative ClassificationA61J1/1475, A61J2001/2006, A61J1/1406, A61J1/10European ClassificationA61J1/14B, A61J1/14PLegal EventsDateCodeEventDescriptionMay 5, 2014FPAYFee paymentYear of fee payment: 4Sep 30, 2005ASAssignmentOwner name: FRESENIUS KABI DEUTSCHLAND GMBH, GERMANYFree format text: CORRECTIVE ASSIGNMENT TO CORRECT THE EXECUTION DATE OF THE SECOND INVENTOR. DOCUMENT PREVIOUSLY RECORDED AT REEL 016472 FRAME 0749;ASSIGNORS:BRANDENBURGER, TORSTEN;RAHIMY, ISMAEL;REEL/FRAME:017554/0385;SIGNING DATES FROM 20041129 TO 20041130Free format text: CORRECTIVE ASSIGNMENT TO CORRECT THE EXECUTION DATE OF THE SECOND INVENTOR. DOCUMENT PREVIOUSLY RECORDED AT REEL 016472 FRAME 0749.;ASSIGNORS:BRANDENBURGER, TORSTEN;RAHIMY, ISMAEL;REEL/FRAME:017554/0385;SIGNING DATES FROM 20041129 TO 20041130Owner name: FRESENIUS KABI DEUTSCHLAND GMBH, GERMANYFree format text: CORRECTIVE ASSIGNMENT TO CORRECT THE EXECUTION DATE OF THE SECOND INVENTOR. DOCUMENT PREVIOUSLY RECORDED AT REEL 016472 FRAME 0749.;ASSIGNORS:BRANDENBURGER, TORSTEN;RAHIMY, ISMAEL;REEL/FRAME:017554/0385;SIGNING DATES FROM 20041129 TO 20041130Apr 20, 2005ASAssignmentOwner name: FRESENIUS KABI DEUTSCHLAND GMBH, GERMANYFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BRANDENBURGER, TORSTEN;RAHIMY, ISMAEL;REEL/FRAME:016472/0749;SIGNING DATES FROM 20041129 TO 20041230RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services