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Patent US6069140 - Pharmaceutical compositions comprising texaphyrins - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsTexaphyrins are provided for use as radiation sensitizers. Advantageous properties of texaphyrins for use as a radiation sensitizer include: i) a low redox potential which allows radiation-induced hydrated electrons to flow to texaphyrin rather than neutralizing hydroxyl radicals, allowing hydroxyl radicals...http://www.google.com/patents/US6069140?utm_source=gb-gplus-sharePatent US6069140 - Pharmaceutical compositions comprising texaphyrinsAdvanced Patent SearchTry the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents.Publication numberUS6069140 APublication typeGrantApplication numberUS 08/970,864Publication dateMay 30, 2000Filing dateNov 14, 1997Priority dateJan 21, 1992Fee statusPaidAlso published asCA2173319A1, CA2173319C, DE69432221D1, DE69432221T2, EP0724457A1, EP0724457B1, US5457183, US5580543, US5583220, US5587371, US5622946, US5632970, US5801229, WO1995010307A1Publication number08970864, 970864, US 6069140 A, US 6069140A, US-A-6069140, US6069140 A, US6069140AInventorsJonathan L. Sessler, Tarak D. Mody, Gregory W. HemmiOriginal AssigneeThe Board Of Regents University Of Texas SystemExport CitationBiBTeX, EndNote, RefManPatent Citations (67), Non-Patent Citations (248), Referenced by (30), Classifications (70), Legal Events (8) External Links: USPTO, USPTO Assignment, EspacenetPharmaceutical compositions comprising texaphyrins
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complexes for enhancing relaxivityUS5504205 *Jul 26, 1994Apr 2, 1996Board Of Regents, University Of Texas SystemReduced sp3 texaphyrinsUS5525325 *Sep 7, 1994Jun 11, 1996Board Of Regents, University Of TexasExpanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocyclesUS5559207 *Apr 14, 1994Sep 24, 1996Board Of Regents, University Of TexasTexaphyrin metal complex mediated ester hydrolysisUS5565552 *Jun 7, 1995Oct 15, 1996Pharmacyclics, Inc.Method of expanded porphyrin-oligonucleotide conjugate synthesisUS5567687 *Sep 21, 1994Oct 22, 1996University Of TexasTexaphyrins and uses thereofUS5569759 *Jul 28, 1993Oct 29, 1996Board Of Regents, University Of Texas SystemWater soluble texaphyrin metal complex preparationUS5583220 *May 24, 1995Dec 10, 1996Pharmacyclics, Inc.Pyrole nitrogen-substituted texaphyrinsUS5587371 *Jun 2, 1995Dec 24, 1996Pharmacyclics, Inc.Texaphyrin-oligonucleotide conjugatesUS5587463 *Mar 8, 1994Dec 24, 1996Board Of Regents, The University Of Texas 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texaphyrinsUS5633354 *Mar 13, 1996May 27, 1997Pharmacyclics, Inc.Phosphoramidite derivatives of texaphyrinsUS5714328 *Jun 7, 1995Feb 3, 1998Board Of Regents, The University Of Texas SystemRNA photocleavage using texaphyrinsUS5733903 *Jul 10, 1996Mar 31, 1998Board Of Regents, The University Of Texas SystemTreatment of neoplastic tissue by water-soluble texaphyrine metal complexesUS5756726 *Jun 6, 1995May 26, 1998Pharmacyclics, Inc.Methods of producing singlet oxygen using compounds having improved functionalizationUS5763172 *Jun 7, 1995Jun 9, 1998Board Of Regents, The University Of Texas SystemMethod of phosphate ester hydrolysisUS5775339 *Aug 19, 1997Jul 7, 1998Pharmacyclics, Inc.Photodynamic therapy of pigment-related lesionsUS5776925 *Jan 25, 1996Jul 7, 1998Pharmacyclics, Inc.Methods for cancer chemosensitizationUS5798491 *Jun 2, 1995Aug 25, 1998Board Of Regents, The University Of Texas SystemMulti-mechanistic chemical cleavage using certain metal complexesUS5801229 *Sep 13, 1996Sep 1, 1998The Board Of Regents, University Of Texas SystemMetal complexes of texaphyrinsEP0111418A2 *Dec 6, 1983Jun 20, 1984Edelson, Richard L., Dr.System for externally treating the bloodEP0196515A1 *Mar 13, 1986Oct 8, 1986Baxter Travenol Laboratories, Inc.Photodynamic inactivation of virus in therapeutic protein compositionsEP0233701A2 *Jan 16, 1987Aug 26, 1987HAMARI YAKUHIN KOGYO KABUSHIKI KAISHA also known as HAMARI CHEMICALS, LTD.Porphyrin derivativesWO1990001208A1 *Jul 28, 1989Feb 8, 1990Best Industries, Inc.Device and method for encapsulating radioactive materialsWO1990010633A1 *Mar 6, 1990Sep 20, 1990Board Of Regents, The University Of Texas SystemExpanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocyclesWO1991019730A1 *Jun 3, 1991Dec 26, 1991Monsanto CompanyRna hydrolysis/cleavageWO1992001781A1 *Jun 27, 1991Feb 6, 1992The Regents Of The University Of CaliforniaAntibody-mediated cofactor-driven reactionsWO1993014093A1 *Jan 7, 1993Jul 22, 1993Board Of 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Properties CompanySubstituted imidazo ring systems and methodsUS8697873Mar 24, 2005Apr 15, 20143M Innovative Properties CompanyAmide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridinesUS8735421Dec 23, 2004May 27, 20143M Innovative Properties CompanyImidazoquinolinyl sulfonamidesUS8802853Dec 17, 2004Aug 12, 20143M Innovative Properties CompanyArylalkenyl and arylalkynyl substituted imidazoquinolinesUS8871782Oct 1, 2004Oct 28, 20143M Innovative Properties CompanyAlkoxy substituted imidazoquinolinesUS9248127Feb 3, 2006Feb 2, 20163M Innovative Properties CompanyAqueous gel formulations containing immune response modifiersUS20030130252 *Dec 12, 2002Jul 10, 2003Pharmacyclics, Inc.Process for affecting neurologic progressionUS20030229131 *Feb 26, 2003Dec 11, 2003Board Of Regents, The University Of Texas SystemCyclo[n]pyrroles and methods theretoUS20060181579 *Feb 14, 2006Aug 17, 2006Brother Kogyo Kabushiki KaishaInkjet Recording ApparatusUS20070259881 *Jun 17, 2005Nov 8, 2007Dellaria Joseph F JrSubstituted Imidazo Ring Systems and MethodsUS20080138292 *Sep 14, 2007Jun 12, 2008Massachusetts Institute Of TechnologySensors for fluorescence and magnetic resonance imagingUS20090105295 *Nov 12, 2004Apr 23, 2009Coley Pharmaceutical Group, Inc.Hydroxylamine substituted imidazoquinolines* Cited by examinerClassifications U.S. Classification514/185, 514/23, 514/410, 514/19.3, 514/15.1International ClassificationB01J31/18, A61K31/407, A61P35/02, B01J31/16, A61K31/40, B01J31/06, A61K51/00, A61P43/00, A61K47/48, C07H21/00, A61K49/06, A61K51/04, A61K41/00, A61K49/08, C07D487/22, A61K49/00, A61L2/00Cooperative ClassificationB01J31/1815, B01J2531/38, C07D487/22, B01J2531/847, A61K41/0038, B01J2531/37, A61K49/0021, B01J2531/27, A61K49/10, B01J31/1658, B01J31/061, B01J2531/72, A61K41/0076, A61K49/085, A61K49/126, A61K49/106, A61L2/0011, B01J2531/26, B01J2531/23, A61K51/0485, C07H21/00, A61K41/0057, B01J2531/28, B01J2531/96, A61K47/48069, B01J31/1805, B01J2531/36, B01J2531/025, B01J2531/845, B01J2531/842, A61K49/0054European ClassificationA61K41/00W10, C07H21/00, B01J31/16D2, A61K41/00W, B01J31/18B, A61K49/10, B01J31/18B2B, A61K49/10C8, A61K49/12P, A61K41/00P, A61L2/00P2, A61K47/48H4H4, A61K49/08Z, A61K51/04L16, A61K49/00P4F4C, A61K49/00P4F8K, C07D487/22Legal EventsDateCodeEventDescriptionDec 1, 2003FPAYFee paymentYear of fee payment: 4Oct 24, 2006CCCertificate of correctionNov 30, 2007FPAYFee paymentYear of fee payment: 8Jan 9, 2012REMIMaintenance fee reminder mailedMay 25, 2012FPAYFee paymentYear of fee payment: 12May 25, 2012SULPSurcharge for late paymentYear of fee payment: 11Jul 18, 2015ASAssignmentOwner name: PHARMACYCLICS, INC., CALIFORNIAFree format text: MERGER;ASSIGNOR:OXFORD AMHERST CORPORATION;REEL/FRAME:036130/0254Effective date: 20150526Owner name: PHARMACYCLICS LLC, CALIFORNIAFree format text: MERGER AND CHANGE OF NAME;ASSIGNORS:PHARMACYCLICS, INC.;OXFORD AMHERST LLC;REEL/FRAME:036130/0285Effective date: 20150526May 18, 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