Source: http://www.google.com/patents/US6183763?dq=georgia+pacific+dispenser&ei=3350T6jaCc-q0AHQucGAAw
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Matched Legal Cases: ['application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08', 'application No. 08']

Patent US6183763 - Antimicrobial wipes which provide improved immediate germ reduction - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsThe present invention relates to an antimicrobial wipe effective against Gram positive bacteria, Gram negative bacteria, fungi, yeasts, molds, and viruses comprising a porous or absorbent sheet impregnated with an antimicrobial cleansing composition, wherein the antimicrobial cleansing composition comprises...http://www.google.com/patents/US6183763?utm_source=gb-gplus-sharePatent US6183763 - Antimicrobial wipes which provide improved immediate germ reductionAdvanced Patent SearchPublication numberUS6183763 B1Publication typeGrantApplication numberUS 08/868,687Publication dateFeb 6, 2001Filing dateJun 4, 1997Priority dateJun 4, 1997Fee statusLapsedPublication number08868687, 868687, US 6183763 B1, US 6183763B1, US-B1-6183763, US6183763 B1, US6183763B1InventorsPeter William Beerse, Jeffrey Michael Morgan, Kathleen Grieshop Baier, Wei Cen, Theresa Anne BakkenOriginal AssigneeProcter & Gamble CompanyExport CitationBiBTeX, EndNote, RefManPatent Citations (94), Non-Patent Citations (60), Referenced by (76), Classifications (11), Legal Events (4) External Links: USPTO, USPTO Assignment, EspacenetAntimicrobial wipes which provide improved immediate germ reduction
US 6183763 B1Abstract
What is claimed is: 1. An antimicrobial wipe effective against Gram positive bacteria, Gram negative bacteria, fungi, yeasts, molds, and viruses comprising a porous or absorbent sheet impregnated with an antimicrobial cleansing composition, wherein the antimicrobial cleansing composition comprises the following individual components:
a. from about 0.001% to about 5.0%, by weight of the antimicrobial cleansing composition, of an antimicrobial active; b. from about 0.05% to about 10%, by weight of the antimicrobial cleansing composition, of an anionic surfactant; c. from about 0.1% to about 10%, by weight of the antimicrobial cleansing composition, of a proton donating agent; and d. from about 3% to about 99.85%, by weight of the antimicrobial cleansing composition, water; wherein the composition is adjusted to a pH of from about 3.0 to about 6.0; wherein the antimicrobial cleansing composition exhibits a One-wash Immediate Germ Reduction Index of greater than about 1.3; and wherein the antimicrobial cleansing composition has a Mildness Index of greater than 0.3. 2. An antimicrobial wipe according to claim 1 wherein the antimicrobial active is selected from the group consisting of triclosan, triclocarban, piroctone olamine, PCMX, ZPT, natural essential oils and their key ingredients, and mixtures thereof.
a. from about 0.05% to about 1.0%, by weight of the antimicrobial cleansing composition, of an antimicrobial active; b. from about 0.1% to about 2%, by weight of the antimicrobial cleansing composition, of an anionic surfactant; c. from about 0.5% to about 8%, by weight of the antimicrobial cleansing composition, of a proton donating agent; and d. from about 3% to about 99.85%, by weight of the antimicrobial cleansing composition, water; wherein the composition is adjusted to a pH of from about 3.0 to about 6.0; wherein the antimicrobial cleansing composition exhibits a One-wash Immediate Germ Reduction Index of greater than about 1.7; and wherein the antimicrobial composition has a Mildness Index of greater than 0.4. 10. An antimicrobial wipe according to claim 9 wherein the antimicrobial active is selected from the group consisting of triclosan, triclocarban, piroctone olamine, PCMX, ZPT, natural essential oils and their key ingredients, and mixtures thereof.
Currently marketed Nice'n Clean�, Wash'n Dry� and No More Germies� are all antibacterial wipes which utilize harsh cationic surfactants with no additional antibacterial active. These products do not provide the improved immediate germ reduction and are harsh to the skin. Current wipes have been found to give about 1.0 log reduction of germs in One-wash tests.
Hibiclens� Surgical Scrub provides 2.5 to 3.0 log reduction in germs in one wash, and U.S. Pat. No. 3,141,821, issued to Compeau Jul. 21, 1964; Irgasan DP 300 (Triclosan) �) technical literature from Ciba-Giegy, Inc., “Basic Formulation for Hand Disinfection 89/42/01”; Bartzokas, C. A., et al, “Evaluation of the Skin Disinfecting Activity and Cumulative Effect of Chlorhexidine and Triclosan Handwash Preparations on Hands Artificially Contaminated with Serratia marcescens”, Infection Control, 1987/Vol. 8, No. 4; all set forth antibacterial skin cleansers compositions which could provide improved immediate germ reduction using certain anionic surfactants, antimicrobial actives and acids. However, the selection, therein, of highly active surfactants or cationic actives with safety issues (i.e. chlorohexidine gluconate) results in personal cleansing compositions which are drying and harsh, or potentially unsafe to use.
Methylchloroisothiazol inone/methyl isothiazolinone (Kathon CG�)
3,4,4′-Trichlorocarbanilides (Triclocarban� TCC)
In order to achieve the mildness required of the present invention, optional ingredients to enhance the mildness to the skin can be added. These ingredients include cationic and nonionic polymers, co-surfactants, moisturizers and mixtures thereof. Polymers useful herein include polyethylene glycols, polypropylene glycols, hydrolyzed silk proteins, hydrolyzed milk proteins, hydrolyzed keratin proteins, guar hydroxypropyltrimonium chloride, polyquats, silicone polymers and mixtures thereof. When used, the mildness enhancing polymers comprise from about 0.1% to about 1%, preferably from about 0.2% to about 1.0%, and more preferably from about 0.2% to about 0.6%, by weight of the antimicrobial cleansing composition, of the composition. Co-surfactants useful herein include nonionic surfactants such as the Genapol� 24 series of ethoxylated alcohols, POE(20) sorbitan monooleate (Tween� 80), polyethylene glycol cocoate and Pluronic� propylene oxide/ethylene oxide block polymers, and amphoteric surfactants such as alkyl betaines, alkyl sultaines, alkyl amphoacetates, alkyl amphodiacetates, alkyl amphopropionates, and alkyl amphodipropionates. When used, the mildness enhancing co-surfactants comprise from about 20% to about 70%, preferably from about 20% to about 50%, by weight of the anionic surfactant, of the cleansing composition.
The concentration of test substance, in ppm, that decreases the bioluminescence of the Microtox Acute Toxicity Reagent by 50% from the starting value (EC50 Value) can be calculated using the Run Statistics on Data File option of the Microtox Software (recommended) or by conducting a linear regression of the data (% reduction vs. log of concentration). % Reductions are calculated using the following formulas: Final   Reading   of   Reagent   Blank Initial   Reading   of   Reagent   Blank = Correction��Factor Final   Reading   of   Reagent   with   Diluted   Test   Substance Initial   Reading   of   Reagent   with   Diluted   Test   Substance = Reduction   Factor x where   x   means   at    a   corresponding   concentration %   Reduction = Correction   Factor x - Reduction   Factor Correction   Factor The Microtox Index is the EC50 value in ppm.
The skin on each treatment area is evaluated by an expert grader at baseline and three hours after the final study wash. The treatment areas are evaluated under 2.75�magnification (model KFM-1A Luxo Illuminated Magnifying Lamp, Marshall Industries, Dayton, Ohio) with controlled lighting (General Electric Cool White, 22-watt, 8″ Circuline fluorescent bulb).
The Wells-Brookfield Cone/Plate Model DV-II+Viscometer is used to determine the viscosity of the antimicrobial cleansing compositions herein. The determination is performed at 25� C. with the 2.4 cm� cone (Spindle CP-41) measuring system with a gap of 0.013 mm between the two small pins on the respective cone and plate. The measurement is performed by injecting 0.5 ml of the sample to be analyzed between the cone and plate and rotating the cone at a set speed of 1 rpm. The resistance to the rotation of the cone produces a torque that is proportional to the shear stress of the liquid sample. The amount of torque is read and computed by the viscometer into absolute centipoise units (mPa's) based on geometric constants of the cone, the rate of rotation, and the stress related torque.
Primary Chain Length
Head Group Size
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19970604 TO 19970904Aug 25, 2004REMIMaintenance fee reminder mailedFeb 7, 2005LAPSLapse for failure to pay maintenance feesApr 5, 2005FPExpired due to failure to pay maintenance feeEffective date: 20050206RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services