Source: http://www.google.com/patents/US8057595?dq=5,545,531
Timestamp: 2017-07-21 20:06:37
Document Index: 164740393

Matched Legal Cases: ['Application No. 2004273794', 'Application No. 2004273794', 'Application No. 2004273794', 'Application No. 200480032523', 'Application No. 200480032523', 'Application No. 200480032523', 'Application No. 2002', 'Application No. 2002']

Patent US8057595 - Bone cement compositions having fiber-reinforcement and/or increased flowability - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsThe present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized...http://www.google.com/patents/US8057595?utm_source=gb-gplus-sharePatent US8057595 - Bone cement compositions having fiber-reinforcement and/or increased flowabilityAdvanced Patent SearchTry the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents.Publication numberUS8057595 B2Publication typeGrantApplication numberUS 12/611,716Publication dateNov 15, 2011Filing dateNov 3, 2009Priority dateSep 5, 2003Fee statusPaidAlso published asCA2539751A1, CA2539751C, EP1663333A2, US7494950, US7628851, US20050208094, US20080226691, US20100048763, WO2005027988A2, WO2005027988A3Publication number12611716, 611716, US 8057595 B2, US 8057595B2, US-B2-8057595, US8057595 B2, US8057595B2InventorsBryan Monro Armitage, Ira Ison, Mark Fulmer, Sean Kerr, Michael Lehmicke, Patrick Leamy, William SchifferOriginal AssigneeSynthes Usa, LlcExport CitationBiBTeX, EndNote, RefManPatent Citations (61), Non-Patent Citations (37), Referenced by (2), Classifications (36), Legal Events (1) External Links: USPTO, USPTO Assignment, EspacenetBone cement compositions having fiber-reinforcement and/or increased flowability
optionally grind the calcium salt-containing component, especially when relatively small particle sizes of this component are desirable; incorporate a flow additive described above to form a flowable calcium phosphate-containing composition, particularly for compositions processed using conventional viscoelastic-liquid forming or liquid-setting means (e.g., by flow through an aperture such as injection or by unrestrained flow such as pouring. molding by hand, or the like, or a combination thereof); optionally, incorporate demineralized bone (e.g., by hand, using a rotary mixer, or using a pneumatic mixer) to form a calcium salt/demineralized bone-containing component; optionally incorporate a plurality of discrete fibers (e.g., by hand, using a rotary mixer, or using a pneumatic mixer) described above; optionally pre-treat a void and/or defect (e.g., in a bone), and/or an in vivo area proximal thereto, for receiving the composition according to the invention; optionally position and/or anchor continuous reinforcing fibers near, around, and/or within the void and/or defect, particularly for compositions processed using conventional viscoelastic-liquid forming or liquid-setting means (e.g., by flow through an aperture such as injection or by unrestrained flow such as pouring, molding by hand, or the like, or a combination thereof); introduce the flowable calcium salt-containing component into, onto, and/or proximal to the void and/or defect in order to at least partially coat and/or fill the void and/or defect, thus forming an implantable composite material; and optionally post-treat the at least partially coated and/or filled void and/or defect containing the implantable composite material and/or the in vivo area proximal thereto to form a biocompatible and/or semi-permeable surface (e.g., by exposing the available surface to a catalytic and/or reactive compound to chemically alter the available surface; to set or to hasten the setting of the composition at the available surface; to protect the available surface, and optionally the entire implantable composite material, from undesired immune response; to induce at the available surface, and/or optionally within the entire implantable composite material, an increased immune response; to establish a semi-permeable layer through which and/or into which only certain desirable biological compounds may pass, while excluding certain other undesirable biological compounds; or the like; or some combination thereof). Another aspect of the present invention relates to a kit or packaging system for storing, preparing, mixing, and/or administering compositions according to the invention. Advantageously, the kit or packaging system can contain the composite components in at least two separate compartments. In this embodiment, the solid portion of the calcium salt-containing component according to the invention (e.g., bone cement) can be present in one compartment, which can optionally also contain the fiber component(s) to form a solid or “dry” components compartment, while the liquid portion of the calcium salt-containing component according to the invention (e.g., setting solution) can be present in another compartment, which can optionally also contain the flow additive component to form a liquid or “wet” components compartment. A non-limiting example of a two-compartment kit is described in U.S. Pat. No. 6,149,655, the entire content of which is hereby incorporated by express reference hereto.
1% (3 mm × 16-20 μm) L6
2% (3 mm × 16-20 μm) L6
2% (6 mm × 16-20 μm) L6
1% (8 mm × 16-20 μm) L6
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T., et al., "Bone-Shaped Short Fiber Composites—An Overview", Materials Science and Engineering: A, 326(2), (2002), 208-227.* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS8778378Dec 21, 2009Jul 15, 2014Orthovita, Inc.Bioactive antibacterial bone graft materialsUS20110150963 *Dec 21, 2009Jun 23, 2011Clineff Theodore DBioactive antibacterial bone graft materials* Cited by examinerClassifications U.S. Classification106/690, 106/691, 106/775, 106/774, 106/35, 106/772, 106/776, 106/780International ClassificationC09K3/00, A61K33/06, C04B12/02, A61K31/74, A61K33/42, C04B28/14, A61L27/50, A61L24/00, A61L27/46, A61L27/42Cooperative ClassificationA61L24/0063, A61K33/06, A61L24/001, A61L24/0084, A61L27/50, A61L27/425, A61K33/42, A61L27/46, A61K31/74European ClassificationA61K33/42, A61K31/74, A61K33/06, A61L24/00R4E, A61L24/00R2E, A61L27/50, A61L24/00H, A61L27/42E, A61L27/46Legal EventsDateCodeEventDescriptionApr 29, 2015FPAYFee paymentYear of fee payment: 4RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services