Source: https://patents.google.com/patent/CN103269647B/en
Timestamp: 2019-12-14 16:23:34
Document Index: 110404100

Matched Legal Cases: ['art 114', 'art 124', 'art 118', 'art 118', 'art 118', 'art 306']

CN103269647B - Adjustable anchor system and method - Google Patents
Adjustable anchor system and method Download PDF
CN103269647B
CN103269647B CN201180061812.1A CN201180061812A CN103269647B CN 103269647 B CN103269647 B CN 103269647B CN 201180061812 A CN201180061812 A CN 201180061812A CN 103269647 B CN103269647 B CN 103269647B
CN201180061812.1A
CN103269647A (en
J.埃尔南德斯
M.Z.森冈
G.R.怀特塔科
G.B.麦卡里斯特
2010-12-23 Priority to US12/977146 priority
2011-12-23 Application filed by 德普伊米特克有限责任公司 filed Critical 德普伊米特克有限责任公司
2011-12-23 Priority to PCT/US2011/067119 priority patent/WO2012088496A2/en
2013-08-28 Publication of CN103269647A publication Critical patent/CN103269647A/en
2017-09-12 Publication of CN103269647B publication Critical patent/CN103269647B/en
The invention discloses a kind of adjustable anchor system, the adjustable anchor system can secure the tissue to bone and including holdfast, and the holdfast has the collapsible suture collar attached with it and is connected to the tissue apposition line of the collapsible suture collar.It is downloaded in the tissue the tissue apposition is traditional thread binding and the holdfast is implanted into after the bone, makes the collapsible collar collapse to be tensioned the tissue apposition line.
Adjustable anchor system and method
Present patent application is the part for the U.S. Patent Application Serial Number (12/977,146) submitted on December 23rd, 2010 Continuation application, the entire content of the U.S. Patent application is incorporated herein by reference.
The present invention relates to the system and method for securing the tissue to bone, relate more specifically to without using person's tying to group The adjustable tensioning knitted.
2.The explanation of association area
It is common damage that tendon, ligament or other soft tissues, which are completely disengaged from or are partially disengaged from bone, among sportsman It is especially common.Organize disengaging may during falling down because overexerting or occurring due to various other reasons.Especially It is when tissue is completely from its related diastasis of bone, it usually needs surgical operation.Currently available tissue attachment arrangement includes spiral shell Nail, staple, suture anchor and hobnail.Provided in Cauldwell et al. U.S. Patent Application Publication 2008/0147063 The example of hollow suture anchor.
Claim that for the suture implant system of " no knot ", so-called " no knot " is i.e. without surgeon in operation in the presence of many Tying.Many such systems are driven into the depth in bone come control action in the tension force of tissue by holdfast.Lizardi United States Patent (USP) 5,782,864 and 7,381,213 disclose certain form of suture anchor, its obtain regular length suture The collar.Thal is retouched in United States Patent (USP) 5,569,306 and 6,045,574 and in U.S. Patent Application Publication 2009/0138042 The adjustable collar using the holdfast element in plug-in-sleeve has been stated without knot anchor unit.
Exist for repairing the tissue of tear or damage, the especially suitable suture anchor system with Slipped Clove Hitch for repairing meniscus Have disclosed in Selvitelli et al. United States Patent (USP) 7,390,332, and be used for from DePuy Mitek Inc. (325Paramount Drive, Raynham, Massachusetts02767) commercially available OmniSpanTMMeniscal repairs System.For repair tissue there are Slipped Clove Hitch and other suture anchor systems of lock knot to include Wenstrom, Jr. United States Patent (USP) 6,767,037。
Accordingly, it is desirable to which especially holdfast is fixed to without surgeon's tying in arthroscopic type operation Structural tension force is adjusted after in bone.
According to the present invention suture anchor system include suture anchor, be attached to holdfast the collapsible suture collar and It is attached to the tissue apposition line of the collapsible suture collar.
In one aspect of the invention, tissue apposition line cyclization passes through the collapsible collar.Tissue apposition line can be collapsed by non- The suture length of the contracting collar is formed by the identical suture length for forming the collapsible collar.In one aspect of the invention, Tissue apposition line has the feature being selected from such as following table：Material, construction, size and coating, the feature are different from collapsible set Such same characteristic features of ring.For example, tissue apposition line can be to organizing the non-stimulated and collapsible collar can be by following suture Formed, the suture can slide relatively easily, with high intensity, fully be tied in a knot or other for tissue apposition line not This vital category feature.Preferably, the collapsible suture collar has the coefficient of friction less than tissue apposition line.
Preferably, the collapsible suture collar includes Slipped Clove Hitch, and a part for the wherein suture collar may pass through Slipped Clove Hitch progress Drawing is so that its own is collapsed.Preferably, Slipped Clove Hitch includes fixed afterbody and column extension.In another aspect of this invention, group Knitting suture includes fixed afterbody.
Preferably, the attachment members on holdfast pass through the collapsible suture collar that the collapsible collar is attached into holdfast.
Preferably, holdfast has center axially intubation, and the collapsible collar includes Slipped Clove Hitch（The Slipped Clove Hitch has from its extension Column extension, wherein the tension force being applied on column extension makes the collar collapse）, and the collapsible collar and column extension Proximally extend intubation.Preferably, the post in holdfast extends there through the collapsible collar the collapsible collar is attached into holdfast. In one aspect of the invention, Slipped Clove Hitch is arranged on the distal side of post.It is therefore preferred that column extension bypasses holding surface, post exists The collapsible collar is passed through at the neighbouring holding surface and then intubation is proximally passed.In such configuration, Slipped Clove Hitch is set In the nearside of post.In another aspect of this invention, tissue apposition line includes fixed afterbody.
Preferably, bone copulational protuberance is provided around suture anchor.Preferably, holdfast has elongated cylinder form, Pierced so as to be fixedly received in the hole in bone.Additionally preferably, suture anchor, the collapsible collar and tissue apposition line To be sterile and be packaged in fungi-proofing encapsulation, the fungi-proofing encapsulation preferably has uses these parts as described herein Soft tissue is attached to the specification of bone.
In one aspect of the invention, suture container is provided in suture anchor to be used to accommodate tissue apposition line.Seam Zygonema eyelet device may include the eyelet of the far-end positioned at suture anchor.Eyelet can be formed by overlapping arm, so as to allow to suture In the traditional thread binding eyelet being downloaded between arm.Alternatively, eyelet is formed by side wall, and the side wall has what is extended there through Infundibulate slit is to allow suture being loaded into eyelet by slit.Suture container may include positioned at the distal end of holdfast The recess at place, the recess is separated with the collapsible collar with so that the tissue apposition line in recess does not abut appointing for the collapsible collar What movable part.Suture container helps to guide tissue to stitch along the outside of suture anchor when suture anchor is implanted into bone Zygonema, by the capture of tissue apposition line between holdfast and bone.
In one aspect of the invention, holdfast has center axial direction intubation and suture grasper is received through slotting Pipe, so as to be conducive to making tissue apposition line through intubation after the traditional thread binding loading soft tissue by tissue apposition.Suture grasper The elongate body through intubation is preferably included, and with the suture capture mechanism positioned at suture anchor distal side.Suture Capture mechanism can be the flexible material collar that wherein may pass through tissue apposition line.
The method of the present invention is used to soft tissue being attached to bone.It the described method comprises the following steps：Tissue apposition line is worn Cross one piece of soft tissue；Suture anchor is implanted into bone；And make to be attached to holdfast and be attached to the collapsible seam of tissue apposition line The zygonema collar is collapsed, so that tension tissue suture.Preferably, tissue seam is removed before the step of suture anchor is implanted into bone Relaxation in zygonema.
In one aspect of the invention, methods described include the capture of the Part I of tissue apposition line in suture anchor and The step of between bone., can be by second, the tissue apposition line of adjacent tissue's suture Part I before holdfast is implanted into bone Divide by being axially intubated through suture anchor.This contribute to by tissue apposition line and the suture anchor being just implanted alignment, with compared with Tissue apposition line is captured well.Can utilize made through the suture grasper of intubation by following manner Part II through insert Pipe：Part II is loaded into the suture capture mechanism of the suture grasper in holdfast distal side, and then will bag The suture grasper for including suture capture mechanism is proximally drawn through intubation.Preferably, when suture capture is in suture anchor When between nail and bone, soft tissue is set between the Part I and the tissue apposition line and the junction of the collapsible collar On the tissue apposition line.
In one aspect of the invention, before holdfast is implanted into bone, by tissue apposition wire bonding in the remote of suture anchor At end.Preferably, it is downloaded to tissue apposition is traditional thread binding in the eyelet of holdfast distal end.
Preferably, by being attached to suture anchor and passing through the post of the collapsible collar to constrain the collapsible collar.It is preferred that Ground, the collapsible collar includes the lasso trick with collar portion, the Slipped Clove Hitch of the closure collar portion and extends the Slipped Clove Hitch Column extension, thus collapse the collapsible collar the step of include apply tension to column extension.In the side of the present invention Face, holdfast includes center axially intubation, wherein the collar portion and column extension are proximally extended, and wherein collapses The collar is drawn in intubation by the step of collar towards distal side.
In one aspect of the invention, tissue apposition line extends to the collar interconnected with the collapsible collar from soft tissue, because The step of this makes the collapsible collar collapse carrys out the collar of tension tissue suture.
In one aspect of the invention, holdfast includes center axially intubation, wherein the fixation afterbody of Slipped Clove Hitch and column extension Section is proximally extended, and wherein fixes afterbody through soft tissue to be changed into tissue apposition line.
The preferred embodiments of the present invention are illustrated in more detail below in conjunction with accompanying drawing, wherein：
Fig. 1 is the perspective view with closed loop and the adjustable anchor system of the adjustable filament collar according to the present invention；
Figure 1A, 2 and 3 are the schematic cross sectional views of alternative holdfast system according to the present invention；
Fig. 4 is schematic diagram of the closed loop after the part to be affixed to the tissue on bone is pulled through, and the closed loop can be with A part for the adjustable collar is therewith pulled through tissue；
Fig. 5 shows just through retaining collar and is oriented to the holdfast in the hole formed in bone；
Fig. 6 shows the holdfast for applying on column extension and being fixed under tension force in bone；
Fig. 7 shows that column extension is cut up being in the tissue of desired locations under rear final tension force；
Fig. 8 shows the alternative technology shown in Fig. 6 and 7, wherein holdfast engagement closed loop rather than through closed loop；
Fig. 8 A-8C show other embodiment, and the length of wherein closed loop is enough to extend through tissue always from holdfast, such as scheme Shown in zoomed-in view in 8B, and another less preferred embodiment, wherein closed loop is eliminated, and the adjustable collar is complete Through tissue, as seen in fig. 8 c；
Fig. 9 is the top horizontal with being tied according to the Tennessee Slider being used in combination with suture anchor system of the present invention Face figure；
Figure 10 is the anterior elevational view of the cross section of another embodiment of the suture anchor system according to the present invention；
Figure 11 A are the perspective view of the suture anchor main body of the suture anchor system shown in Figure 10；
Figure 11 B are the top plan view of the suture anchor main body shown in Figure 11 A；
Figure 11 C are the side front view of the suture anchor main body shown in Figure 11 A；
Figure 12 is the anterior elevational view of the cross section of another embodiment of the suture anchor system according to the present invention；
Figure 13 A to 13H is using the anterior elevational views of the cross section in the method for the suture anchor system shown in Figure 12；
Figure 14 is the cross section of another embodiment of the suture anchor system with distal side eyelet according to the present invention Anterior elevational view；
Figure 15 A to 15E is using the anterior elevational views of the cross section in the method for the suture anchor system shown in Figure 14；
Figure 16 A are the anterior elevational view of the cross section of another embodiment of the suture anchor system according to the present invention, the seam Closing holdfast system has distal side eyelet and is opened with the interior infundibulate for suture is loaded into eyelet of eyelet is led to Mouthful；
Figure 16 B are the anterior elevational view of the cross section of another embodiment of the suture anchor system according to the present invention, the seam Closing holdfast system has distal side eyelet, and the distal side eyelet has overlapping arm suture is loaded into eyelet；
Figure 16 C are the anterior elevational view of the cross section of another embodiment of the suture anchor system according to the present invention, the seam Closing holdfast system has forked distal end to accommodate suture；
Figure 17 is the anterior elevational view of the cross section of another embodiment of the suture anchor system according to the present invention, wherein sliding Knot is located at the nearside for the collar for being attached to holdfast；And
Figure 18 A to 18H is using the anterior elevational views of the cross section in the method for the suture anchor system shown in Figure 17.
The present invention can be by realizing for securing the tissue to the adjustable anchor system of bone, and the system includes having The holdfast of at least one passage proximally extended to distal end.The passage limits confining region, for example, closure member or limited open Mouthful.Holdfast has at least one the bone connected structure set between the proximal and distal ends.The system also includes the first material and the Two filaments, first material is the closed loop for example formed as preferred regular length and can be set through a part for tissue The first suture put, second filament has end, column extension and Slipped Clove Hitch, and the Slipped Clove Hitch lies in end and column extension Between section, to set up the elongated adjustable-length collar, the collar extends to outside the near-end of holdfast and captures closing for the first material Ring.When applying tension force to column extension as needed, the knot of the second filament is constrained by limited opening or closure member, with Shorten the elongated collar, so that tissue is pulled into holdfast, until reaching required tension force.
Adjustable anchor system 10（Fig. 1）It is thin with suture anchor 12, the regular length closed loop of the first material 14 and second Silk 16, second filament has end 18, column extension 20, slides sheet half hitch 22 and with the and of collar extension 26 The 28 adjustable collar 24.In one kind construction, suture anchor 12 is similar to Cauldwell et al. in U.S. Patent Application Publication Hollow suture anchor disclosed in 2008/0147063, this application is herein incorporated by reference.However, in the holdfast of the present invention In system, column suture engagement member or other closure members are not necessarily required to, one or more sutures or suture prolong Section is stretched through the column suture engagement member or other closure members for use as the constraint to proximally moving；In many knots In structure, limited opening 46 is enough to prevent drawing back for knot 22, and following article is specifically described in more detail relative to Figure 1A -3.
Suture anchor 12 has near-end 30 and distal end 32, and relative distal arm 34 and 36 limits otch 38 between them. Passage 40 is proximally 30 inner chamber for extending to distal incision 38.Although knot 22 is illustrated as extension to illustrate in Fig. 1 To outside otch 38, but during holdfast system 10 is inserted into the patient, knot 22 preferably abut against arm 34 and 36 it Between limited opening 46 in, or in other words by cavity or other structures be maintained at distal end 32, to minimize knot 22 to bone Other outer surfaces of connected structure 42 or holdfast 12 and be fixed with wherein suture anchor 12 bone interference.
One or more bone connected structures 42 of all spiral threads as shown in Figure 1 are formed on the outside of holdfast 12, Or such as other structures of tooth, ridge or other projections, to strengthen the fixation in bone.In one kind construction, suture anchor rotation To be screwed into bone in its proximal end, so as to minimize the power of extraction.In a variety of constructions, formed before insertion holdfast in bone Hole；In other constructions, directly suture anchor is inserted into bone.
It can form one or more passages or groove on the outside of suture anchor, it is such as shown in broken lines in Fig. 1 to wear Cross the groove 44 of bone connected structure 42.Figure 1A, 2 and 3 respectively illustrate according to the present invention adjustable anchor system 10a, 10b and 10c other constructions, they have first collar 14a, 14b, 14c of regular length and the second filament of adjustable-length respectively 16a、16b、16c.Holdfast 12a（Figure 1A）Define the inner chamber 40a and external channel 50 that near-end is extended to from its distal end.Second is thin The Slipped Clove Hitch 22a formed in silk 16a is resisted against on limited opening 46a, and adjustable collar 24a extends through passage 40a to capture Closed loop 14a, and column extension 20a is then located in the water jacket 50 in the construction.
It is by end（Such as the end 18a in Figure 1A）Length remain and be enough to lean against at least one bone connected structure 42a Outside to be captured with supporting with bone photo during insertion, or end is cut to shorter length, this is surgical Preference issues.Following Fig. 6-8 provides the different examples of tip length.In addition, such as limited opening 46a confining region can Be limited at least in part by holdfast 12a be fixed to bone in when and bone engagement, with prevent to column extension 20a apply Tie 22a during power to move together with the 20a of column extension, following article is directed to using detailed according to the step of holdfast system of the invention State.
Holdfast system 10b（Fig. 2）With at least three external channel or groove 52,54 and 56, in this configuration without any inside Passage.Knot 22b is maintained at holdfast 12b distal end by closure member 51, and the closure member is at least in part by holdfast 12b distal side table Face is limited, and the collar 24b extension 26b, 28b are then located in passage 52,54, and the second filament 16b column extension 20b is located in passage 56.As described above, closure member 51 can be partly limited by the engagement of holdfast 12b and bone after fixing.
Holdfast system 10c（Fig. 3）With inner passage 40c, limited openings of the column extension 20c from fixed knot 22c 46c extends through the inner passage.External channel 58,60 carries adjustable collar 16c extension 26c, 28c.Although at this In a little constructions, holdfast 12a, 12b and 12c are shown as not having distal side adjutage, but there is provided one or more in other constructions Such distal side extension or other projections, the U.S. of patent or Lizardi similar to Cauldwell cited above et al. are special Some constructions in profit 7,381,213, the patent is equally herein incorporated by reference.In other constructions, in holdfast Far-end provides cylinder or in other words circumferential chamber, bowl-shape or counterbore structure, to be disposed in insertion and fixation procedure Knot 22.
In preferred construction, the collar 14（Also referred to as the first filament）It is linear by one or more suture with the second filament 16 Into.The acceptable diameter of second filament 16 includes No. 0 or No. 2 sutures, for example can be commercially available from DePuy Mitek OrthocordTMSuture, and such as No. 2 to No. 5 sutures of identical or larger diameter suture are preferred for the collar 14, for example From the commercially available Ethibond of EthiconTMSuture.OrthocordTMSuture is close to 55 to 60 percent Five PDSTMPPDO, it is bioabsorbable, and remaining degree is superhigh molecular weight polyethylene Alkene, and EthibondTMSuture is then mainly high-strength polyester.When in some constructions, particularly for shoulder prosthesis, set Ring 14 has about 1 inch of regular length, and the adjustable collar 24 has at least 18 inches of length.It is thin in first or second The bioabsorbable material used in silk（If any）Amount and type main to be carried out specific is directed to by surgeon Surgical operation voluntarily select.
Although the suture of same type can be used for the collar 14 and filament 16, will preferably have relatively low surface grinding characteristic Suture be used to form the first material of closed loop 14.Relatively low abrasive characteristic can be by bigger diameter, softer component, softer Braiding, the combination of pigtail or strand form or these features is played to realize.In some constructions, the suture material system of closed loop 14 There is fixed knot, to form the collar 14 of regular length.In other constructions, the collar 14 is molded or is otherwise formed into material Ring.
In some constructions, slidably sheet half hitch will be described as by knot 22, but after reading this disclosure, other conjunctions It is suitable peering to will be apparent for the those of ordinary skill in suture tying field.As used herein, term " can be slided It is dynamic " be intended to include slidably, lockable knot and slidably tie.Several suitable knot is purchased from DePuy Mitek's Arthroscopic Knot Tying Manual(2005)（《Arthroscope tying handbook》, 2005）And Wenstrom, Jr. United States Patent (USP) 6,767,037 in be described.
Fig. 4-7 shows a step according to the present invention for utilization hollow holdfast system similar to Figure 1, for inciting somebody to action Tissue 68 is attached to bone 80.For the sake of simplicity and clarity, when description is directed to the system shown in the step, the accompanying drawing mark of use Number system 10 is continued to use（Fig. 1）Numeral used, although can also be in a similar fashion using having as shown in other figures The many other types of holdfast of different filament extension constructions.To there is the initial suture 70 of pin 72 in distal end（Fig. 4）Wear Tissue 68 is crossed, at least to pull closed loop 14 at least partially through tissue 68.Alternatively, by suture conveyer Tool is inserted through tissue 68, to catch closed loop 14 and be pulled through tissue 68.The elongated adjustable collar 24 is pulled to pass through The degree of tissue 68, and holdfast be through or the engagement closed loop 14 or adjustable collar 24, have more below in conjunction with Fig. 8-8C Detailed description.
In this step, enter spongiosa layer 86 through the compact substance layer 84 of bone 80 in required reparation position and form hole 82 （Fig. 4）.By holdfast 12（Fig. 5）The opening 89 passed through shown in arrow 90 in closed loop 14 is pressed, and is fixed to as shown in Figure 6 in bone. Preferably, holdfast 12 is passed through after the opening 89 in closed loop 14, and column extension 20 is extracted out from closed loop 14（Fig. 5）, to cause post Shape extension 20 can one of the adjustable collar extension of direct pull pass through knot 22, without the constraint by closed loop 14.In the construction In, end 18 is trapped between a part for the distal end 32 of bone 86 and holdfast 12, and Slipped Clove Hitch 22 is then by limited in inner chamber 40 Opening fix.Alternatively, end 18 has enough length, so that its outside along holdfast 12 is proximally Extension, crosses multiple bone connected structures 42 as shown by dashed lines, length is 18d；Or be length shorter as shown in Figure 8 18e。
Fixed holdfast 12（Fig. 6）Afterwards, the direction as shown in arrow 92 applies nearside tension force to column extension 20.Work as column Extension 20 to nearside move when, with shortening for extension 26 and 28, the adjustable collar 24 easily slides through closed loop 14.Tissue 68 are thus pulled to holdfast 12, until the final required position under tension force needed for reaching, as shown in Figure 7.Closed loop 14 is first The elongated collar 24 is engaged at position 96 and the second place 98.
Show other systems and method according to the present invention using the confession as the final configuration shown in Fig. 7 in Fig. 8-8C The alternative solution of selection.End 18e means short（Fig. 8）So that it is not trapped between holdfast 12 and bone 80.In this structure In making, end 18e is maintained in bone hole 82, and is not placed under any kind of tension force.
Except needing to make the opening 89 in closed loop 14（Fig. 5）More than the girth of holdfast 12 to cause holdfast 12 can pass completely through Outside closed loop 14, in other constructions, distal end 32 engages a part for closed loop 14, as shown in Figure 8.The engagement of filament can be such as Completed shown in Figure 11 and 12 of Lizardi United States Patent (USP) 7,381,213.However, one reached of the invention is beneficial Effect is, by pulling the column extension of the adjustable collar, can after fixed holdfast further tension tissue 68.The present invention Another beneficial effect be, rivet inserter or driver can be removed before being finally tensioned and positioning tissue to be repaired And related driving apparatus, to provide the surgeon with improved vision and touch feedback.
The other structures of filament are shown in Fig. 8 A-8C.Holdfast 12（Fig. 8 A）Filament portion 118 is engaged, it passes through tissue 68 appear in another proximal side of annular region shown in 100.In the construction that Fig. 8 B are directed to shown in the annular region 100, The adjustable collar 124 passes through a part for closed loop 114.In other words, identical filament extension forms single regular length and closed The part 114 and 118 of ring.The structure be preferably as the adjustable collar 124 size reduce when, the adjustable collar 124 Extension can slip over closed loop filament in position 116, and be not passed through tissue.
By contrast, in Fig. 8 A Fig. 8 C of alternate configuration are represented, the extension of adjustable part 124 passes through tissue 68, And adjustable extension forms the part 118 engaged by the distal end 32 of holdfast 12 after exposing.In other words, represented in Fig. 8 C Without using closed loop in configuration.However, the collar for cancelling regular length is less desirable, because the adjustable collar may tend to voluntarily lock It is fixed, and may be combined with the soft tissue that it is passed through or cause soft tissue injury.Even if holdfast passes completely through the adjustable collar, can The mode collar still may be susceptible to self-locked.In addition, unless the extension of part 118 is outside the groove along holdfast 12 or other Correctly alignd in passage, otherwise the interference fit with bone can further interfere with part 118（Fig. 8 C）Adjustability.
Tennessee Slider knots 202 can be used with the suture 200 being used in combination according to the holdfast of the present invention（Fig. 9） To replace sheet half hitch 22.The suture includes the collar 204, column extension 206 and end 208.Post is passed through in end 208 Above shape extension 206, then pass through behind column extension 206, then pass through the collar 204 above and finally in column Extension 206 is passed below.
Figure 10 and Figure 11 A to 11C show another embodiment of the suture anchor 210 according to the present invention.The suture Holdfast includes the main body 212 with near-end 214 and distal end 216, and wherein axial bore 218 passes through near-end 214.Distally 216 two Slotted between individual distal side 222 using saddle 220.Hole 224 extends axially through saddle 220.Around main body 212 Ring-type hangnail flange 225 provides enhanced fixation.
Suture 200 with Tennessee Slider knots 202 is positioned in holdfast 210, its distal end of mesopore 224 Knot 202, which is located at, to be formed in the groove 227 in side 222, and the fixation afterbody 226 of the collar 204 proximally passes through hole from knot 202 224, and the collar 204 adjustable tail 228 around saddle 220 to engage knot 202.The collar 204 proximally extends inner chamber 218.Column extension 206 proximally extends around the side of saddle 220 with the opposite side of adjustable tail 228, and also proximally Extend inner chamber 218.Holdfast 210 can be used in the way of similar to above-described embodiment.
Figure 12 and Figure 13 A to 13G show the alternative step being used in combination with according to the suture anchor of the present invention Suddenly.Holdfast system 230 includes suture anchor 210, and the suture anchor 210 has the suture 200 assembled as shown in Figure 10, and And with flexible suture line acquisition equipment 232, the flexible suture line acquisition equipment 232 has the suture through inner chamber 218 Capture the collar 234（For example from DePuy Mitek, Inc.of Raynham, MA) commercially available Chia Percpasser）, its The middle suture capture collar 234 is located at the distal side of holdfast main body 212.The tissue apposition line 236 of independent length is passed through into the collar 204。
Generally, holdfast system 230 is used with through intubation in arthroscope mode, the intubation is by through the skin of patient 238 to pending reparation tissue 240 and bone 242, but do not show that holdfast system here preferably to lay stress on seam In the assembling and motion of zygonema 200 and 236 and suture anchor 210.First, bone hole 244 is produced near tissue 240（Figure 13A）.Tissue apposition line 236 is passed through into tissue 240（Such as rotary sleeve tendon）, then by suture from intubation（It is not shown）In It is drawn out backward to the outside of skin 238（Figure 13 B）, the tissue apposition line 236 can be captured through suture cover here Ring 234（Figure 13 C）.For this purpose, it can be used for by the suture conveyer of suture through tissue（For example, being purchased from DePuy Mitek, Inc. (Raynham, MA) EXPRESSEW flexible suture line conveyers）.By suture acquisition equipment 232 Proximally inner chamber 218 is pulled out so that tissue apposition line 236 passes through inner chamber 218（Figure 13 D）.Then by suture anchor 210 along insert Pipe（It is not shown）It is sent to bone hole 244.Suture anchor distal end 216 is arranged in hole 244 and removed from tissue apposition line 236 Go relaxation（Figure 13 E）.Then holdfast 210 is driven into bone hole 244, tissue apposition line 236 is thus locked in the He of holdfast 210 Between bone 242（Figure 13 F）.Preferably, holdfast 210 is inserted and is driven into bone hole 244 via the driver 248 with intubation Interior, wherein column extension 206 is located across in the intubation 250 of driver 248.Holdfast 210 is being driven into bone hole 244 it Afterwards, driver 248 is preferably removed（Figure 13 G）And then drawing column extension 206 is with the collar 204 and the tension tissue of collapsing Suture 236（Figure 13 H）.
When the collar 204 of collapsing is to be tensioned repair tissue, the combination with the collapsible collar 204 and tissue apposition line 236 Greater advantage is provided.The collar 204 is slided on tissue apposition line 236 rather than own slip passes through tissue, so that be easier to Repair tissue is tensioned, because the coefficient of friction between the collar 204 and tissue apposition line 236 will be worn less than the own slip of the collar 204 The situation of tissue is crossed, so that any influence for tissue is minimized.
Although illustrated as with single holdfast 210, but common tissue repair can relate to row's holdfast or multiple rows of holdfast.Holdfast 210 and other embodiment can be used for during for example double rotary sleeve is repaired, wherein the first inboard row holdfast is arranged under rotary sleeve Face, suture extends up through rotary sleeve from the first inboard row holdfast and walked to positioned at the second of rotary sleeve adjacent edges Outboard row holdfast.The suture for extending up through rotary sleeve from inboard row may replace tissue apposition line 236 and can be by holdfast 210 captures, in this case, suture acquisition equipment will preferably fit through inner chamber 218（As shown in Figure 10）And with After back through the collar 204 so that it will transmit suture to replace tissue apposition line 236 from inner side holdfast.In order to favourable In this collar for loading tissue apposition line, formula of the collapsing collar can be equipped with closed loop（Such as collar 14）, wherein holdfast is through closing Ring and it is resisted against through the tissue apposition line collar with the formula collar that to collapse when collapsing in closed loop.
Figure 14 shows another embodiment of the holdfast system 250 according to the present invention.The holdfast system includes having seam Zygonema 200 and the suture anchor of tissue apposition line 254 252.Holdfast 252 includes the main body 256 with distal end 258 and near-end 260. Axial bore 262 comes from near-end 260 and has confining region 264 wherein.Hangnail flange 266 is around main body 256.Eyelet 268 It is arranged at distal end 258.Suture 200 is located in holdfast, and wherein knot 202 is located at distal end and the He of the collar 204 of confining region 264 Column extension 206 is towards near-end is through confining region 264 and passes inner chamber 262.The about binding 202 of confining region 264.
The step of Figure 15 A to 15E are shown for holdfast system 250, and such as foregoing description, save for clarity Arthroscope intubation and apparatus.Bone hole 270 is formed in the bone 272 of adjacent tissue 276 below patient skin 274（Figure 15 A）. Tissue apposition line 254 is passed through into tissue（Figure 15 B）And through eyelet 268（Figure 15 C）.Suture acquisition equipment 232 can be used （Figure 15 A are not illustrated in into 15E）Through eyelet 268, to be thus easy to suture 254 being loaded into eyelet.Holdfast 252 is set Put at bone hole 270, remove and relax from tissue apposition line 254, and then be driven into bone hole 270 to stitch in tissue by holdfast Zygonema is locked between holdfast 252 and bone 272（It is preferred that in the both sides of holdfast 252）.The tension force applied to column extension 206 makes The collar 204 is collapsed and tension tissue suture 254.
Figure 16 A to 16C show the modification of suture anchor system 250.Holdfast 252a, 252b and 252c like There is similar unit number with holdfast 250, difference is their subscript.Holdfast 252a（Figure 16 A）With eyelet 280, the eyelet 280 has the entrance of infundibulate slit 282 wherein, for tissue apposition line 254a is loaded into eyelet And then prevent it from passing slit 282 backward.Holdfast 252b（Figure 16 B）With eyelet 284, the eyelet 284 is by overlapping arm 286 are formed, and the zigzag path 288 for entering eyelet 284 is thus produced for tissue apposition line 254b.Holdfast 252c（Figure 16 C）Have Forked end 290, the forked end 290 protrudes fork 292 by the distal side that can capture tissue apposition line 254c therebetween and formed.
Figure 17 and Figure 18 A to 18H show another embodiment of the suture anchor system 300 according to the present invention.Should Suture anchor system includes the suture in elongated cylindrical shape with axially intubation 304 and internal suture saddle 306 Holdfast 302.Ring-type barb-shaped flange 308 is acted on around holdfast 302 with the bone fixation for strengthening the holdfast.Suture 310 includes sliding Knot 312, collapsing with long fixed afterbody 316 and collapse afterbody 318 of the formation of Slipped Clove Hitch 312 around suture saddle 306 The contracting collar 314.Suture threading apparatus 320 includes elongated flexible threading 322, and the elongated flexible threading 322 is received through slotting The distal side suture of pipe 304 and termination positioned at the distal side of holdfast 302 captures the collar 324.
In order that with suture anchor system 300, below patient skin 330 and adjacent to soft tissue 332（For example, flesh Tendon）Bone 328 in formed bone hole 326（Figure 18 A）, the soft tissue 332 will be attached to bone 328 using suture anchor system 300. Fixed afterbody 316 is passed through into soft tissue 332 and the outside of skin 330 is guided to backward（Figure 18 B）.Such as step described above Suddenly, the step is preferably performed in arthroscope mode, and in order to be clearly shown the operation of suture anchor system 300 and from The joint mirror device and anchor drive of correlation are eliminated in accompanying drawing.Fixed afterbody 316 is loaded into the suture capture collar 324 It is interior（Figure 18 C）And suture threading apparatus 320 is proximally extracted out to intubation 304 to load fixed afterbody 316 through intubation 304 （Figure 18 D）.Then suture anchor 302 is arranged in the opening of bone hole 326 and removed from fixed afterbody 316 and relaxed（Figure 18E）.When suture anchor 302 is driven into bone hole 326, it captures fixed afterbody 316 between holdfast 302 and bone 328 （Figure 18 F）.Collapsed afterbody 318 by drawing, formula of collapsing knot 312 make the collar 304 collapse and towards suture saddle 306 to Lower movement, so that by fixed afterbody 316 and soft tissue 332 thus is pulled into holdfast 302（Figure 18 G）.Then it can wipe out and collapse Afterbody 318 and fixed afterbody 316 are to complete the step（Figure 18 H）.The knot of gained leaves the position of knot 312 because of fixed afterbody 316 Tension force between the position of the tying of the collar 314 and it is extremely strong, and this tension force is by soft tissue 332 and suture saddle type What the load between part 306 was provided, thus potent fixation is provided.
The novel suture holdfast of the present invention can be made up of a variety of suitable materials, including metal material, not biodegradable The composite of polymer, biodegradable polymers or biodegradable polymers or copolymer and bioceramic.Such as this Term " biodegradable " used in text is defined as referring to degrading and then being preferentially absorbed into the body in vivo or arranged from body The material gone out.Term " bioceramic " as used herein is defined as referring to the ceramic material and glass compatible with bodily tissue Material.Preferably, bioceramic is biodegradable.
Metal material available for the anchor of the manufacture present invention includes stainless steel, titanium, Nitinol or other biocompatibilities Metal material.
Non-biodegradable material available for the anchor of the manufacture present invention includes polyethylene, polypropylene, PEEK（Polyethers ether Ketone）Or other biological compatibility nonabsorable polymer.
Biodegradable polymers available for the anchor used in the manufacture present invention include being selected from aliphatic polyester, poly- ortho acid Ester, condensing model, makrolon, polyurethane, the biodegradable polymers of polyamide and polyalkylene oxide.Preferably, biological it can drop Depolymerization compound is comprised of aliphatic polyester polymers and copolymer and its blend.Generally, aliphatic polyester is synthesized in ring-opening polymerisation.Properly Monomer include but is not limited to lactic acid, lactide（Including L- lactides, D- lactides, Study of Meso-Lactide and D, L mixture）、 Glycolic, glycolide, 6-caprolactone, to dioxanone（1,4- dioxane -2- ketone）, trimethylene carbonate （1,3- dioxane -2- ketone）, δ-valerolactone, and combinations thereof.
Bioceramic available for the compound anchor of the present invention include containing it is single-, it is double-, three-, α-three-, β-three-and four-phosphorus Sour calcium, hydroxyapatite, calcium sulfate, calcium oxide, calcium carbonate, the ceramics of phosphoric acid calcium and magnesium.Particularly preferably use β-tricresyl phosphate Calcium.In addition to bioceramic, bio-vitric can also be used for composite screws.Bio-vitric may include phosphate glass and life Thing glass.
Suitable biocompatibility synthetic polymer may include selected from aliphatic polyester, polyaminoacid, copolymerization (ether-ester), poly- Alkylidene oxalate, polyamide, tyrosine derived polycarbonates, poly- (iminocarbonic ester), poe, polyoxaesters, poly- Carboxylic acid amide esters, the polyoxaesters of amino-contained group, poly- (acid anhydrides), polyphosphazene, polyurethane, polyether-polyurethane, polyester-polyurethane, poly- rich horse The polymer of acid propylene glycol ester, polyhydroxyalkanoatefrom and their blend.
For purposes of the present invention, aliphatic polyester includes but is not limited to the homopolymer and copolymer of following monomer：Lactide （It includes lactic acid, D-, L- and Study of Meso-Lactide）；Glycolide（Including glycolic）；6-caprolactone；To dioxanone （1,4- dioxane -2- ketone）；Trimethylene carbonate（1,3- dioxane -2- ketone）；Trimethylene carbonate Alkyl derivative；δ-valerolactone；Beta-butyrolactone；Gamma-butyrolacton；ε-decalactone；Butyric ester；Hydroxypentanoic acid ethyl ester；1, 4- cyclic heptane dioxide -2- ketone（Including the oxacyclotetradecane -7,14- diketone of its dimer 1,5,8,12- tetra-）；1,5- dioxy cycloheptyls Alkane -2- ketone；6,6- dimethyl -1,4- dioxane -2- ketone；2,5- diketone morpholines；Pivalolactone；In α, α diethyl third Ester；Ethylene carbonate；Oxalic acid vinyl acetate；3- methyl isophthalic acids, 4- dioxane -2,5- diketone；3,3- diethyl -1,4- dioxies Azacyclohexane -2,5- diketone；6,6- dimethyl-cyclic heptane dioxide -2- ketone；6,8- dioxas double-octane -7- ketone and they Blend polymer.Other exemplary polymer or blend polymer includes（It is used as non-limiting examples）Gather to dioxy Cyclohexanone, poly butyric ester-co- hydroxyl valerates, poly- adjacent carbonic ester, poly- amino carbonic ester and PTMC. Aliphatic polyester used in the present invention can be homopolymer or copolymer with straight chain, side chain or hub-and-spoke configuration（Randomly, block, many Block, tapered block, grafting, three block etc.）.For purposes of the present invention, poly- (iminocarbonic ester) is understood to include Kemnitzer and Kohn is in " Handbook of Biodegradable Polymers "（Domb et al. is edited, Hardwood Academic Press, the 251-272 pages, 1997）Described in those polymer.For purposes of the present invention, copolymerization (ether-ester) is understood to include Cohn and Younes in " Journal of Biomaterials Research "（Volume 22, the 993-1009 pages, 1988）And Cohn（Such as PEO/PLA）In " Polymer Preprints "（American Chemical Society's polymer Chemicals Division, the 1st phase of volume 30, page 498,1989 years）Described in those copolyesters-ethers.For purposes of the present invention, gather Alkylidene oxalate includes United States Patent (USP) 4,208,511；4,141,087；4,130,639；4,140,678；4,105,034；With Those described in 4,205,399.Polyphosphazene, by L- lactides, D, L- lactides, lactic acid, glycolide, glycolic, to dioxy The copolymer based on mix monomer, trimer and higher order polymerization that cyclohexanone, trimethylene carbonate and 6-caprolactone are made Thing, such as by Allcock in " The Encyclopedia of Polymer Science "（Volume 13, the 31-41 pages, Wiley Intersciences, John Wiley ＆ Sons, 1988）In and by Vandorpe et al. in " Handbook of Biodegradable Polymers”（Domb et al. is edited, Hardwood Academic Press, the 161-182 pages, 1997）In be described.Condensing model, which includes being derived from, has HOOC-C6H4–O-(CH2)m-O-C6H4-COOH（Wherein " m " It is the integer in the range of 2-8）Those of the binary acid of form, and the binary acid and the aliphatic α with most 12 carbon- The copolymer of omega dibasic acid.Polyoxaesters, polyoxaamides and polyoxaesters comprising amine and/or acylamino- are in the following U.S. It is described in one or more of patent：United States Patent (USP) 5,464,929；5,595,751；5,597,579；5,607,687； 5,618,552；5,620,698；5,645,850；5,648,088；5,698,213；5,700,583；With 5,859,150.Poly- original Acid esters, such as Heller are in " Handbook of Biodegradable Polymers "（Domb et al. is edited, Hardwood Academic Press, the 99-118 pages, 1997）Described in those.
Therefore, although have been shown, be described and pointed out the substantially new knot that the present invention is applied in a preferred embodiment Structure, it is to be understood that, under the premise without departing from the spirit and scope of the present invention, those skilled in the art can be in shown device Form and details and its operation on carry out it is various omit, replace and change.For example, the application's is clearly intended that：Institute is useful It is equal with the combination of reaching same effect, to perform essentially identical function in substantially the same manner those elements and/or step Within the scope of the present invention.Also it is fully intended and it is envisaged that the element in an embodiment is substituted into another reality Apply in example.It is also understood that accompanying drawing is not necessarily drawn to scale, they are only conceptual in itself.Therefore, the present invention only Limited by the scope of the appended claims.
Each single item cited in the application granted patent, pending patent application, patent disclose, journal article, books or Any other bibliography full content is incorporated by reference.
1. a kind of suture anchor system, including：
Suture anchor；
The collapsible suture collar, the collapsible suture collar is attached to the holdfast；With
Tissue apposition line, the linear part for turning into closed loop and being arranged through tissue of the tissue apposition, the tissue apposition Line is attached to the collapsible suture collar,
The wherein described collapsible suture collar is not passed through the tissue.
2. suture anchor system according to claim 1, wherein tissue apposition line cyclization passes through the collapsible set Ring.
3. suture anchor system according to claim 2, wherein the tissue apposition line is not by being the collapsible collar Independent suture length formed.
4. suture anchor system according to claim 3, wherein the tissue apposition line, which has, is selected from material, construction, chi The feature of very little and coating, the feature is different from such same characteristic features of the collapsible collar.
5. suture anchor system according to claim 1, wherein the collapsible suture collar includes Slipped Clove Hitch, the seam A part for the zygonema collar may pass through the Slipped Clove Hitch and be pulled so that its own is collapsed.
6. suture anchor system according to claim 5, wherein the Slipped Clove Hitch includes fixed afterbody and column extension, and And wherein described tissue apposition line includes the fixed afterbody.
7. suture anchor system according to claim 5, wherein attachment members on the holdfast are through described collapsible The suture collar by the collapsible collar to be attached to the holdfast.
8. suture anchor system according to claim 1, wherein：
The holdfast has center axially intubation；
The collapsible collar includes Slipped Clove Hitch and with the column extension extended from the Slipped Clove Hitch, wherein the column extends Tension force in section makes the collar collapse；And
The intubation is proximally extended in the collapsible collar and the column extension.
9. suture anchor system according to claim 8, wherein post in the holdfast through the collapsible collar with The collapsible collar is attached to the holdfast.
10. suture anchor system according to claim 9, wherein the Slipped Clove Hitch is arranged on the distal side of the post.
11. suture anchor system according to claim 9, wherein the Slipped Clove Hitch is arranged on the nearside of the post.
12. suture anchor system according to claim 11, wherein the tissue apposition line includes fixed afterbody.
13. suture anchor system according to claim 1, in addition to around the bone copulational protuberance of the suture anchor.
14. suture anchor system according to claim 1, wherein the suture anchor, the collapsible collar and tissue apposition Line is sterile and is packaged in fungi-proofing encapsulation.
15. suture anchor system according to claim 1, wherein the holdfast has elongated cylinder form, so that Pierced by being fixedly received in the hole in bone.
16. suture anchor system according to claim 1, wherein the collapsible suture collar, which has, is less than described group Knit the coefficient of friction of suture.
17. suture anchor system according to claim 1, in addition to it is described for accommodating in the suture anchor The suture container of tissue apposition line.
18. suture anchor system according to claim 17, wherein the suture container includes being located at the suture The eyelet of the far-end of holdfast.
19. suture anchor system according to claim 18, wherein the eyelet is formed by overlapping arm, so as to allow institute State in the eyelet that suture is loaded between the arm.
20. suture anchor system according to claim 18, wherein the eyelet is formed and wherein infundibulate by side wall Slit passes through the side wall, so as to allow suture being loaded into the eyelet by the slit.
21. suture anchor system according to claim 17, wherein the suture container includes being located at the holdfast Far-end recess, the recess separated with the collapsible collar so that the tissue apposition line in the recess is not abutted Any movable part of the collapsible collar.
22. suture anchor system according to claim 1, wherein：
Suture grasper is received through the intubation, so as to be conducive to after the traditional thread binding loading soft tissue by the tissue apposition The tissue apposition line is set to pass through the intubation.
23. suture anchor system according to claim 22, wherein the suture grasper is included through the intubation Elongate body, and with positioned at the suture anchor distal side suture capture mechanism.
24. suture anchor system according to claim 23, wherein the suture capture mechanism is therefrom may pass through institute State the flexible material collar of tissue apposition line.
CN201180061812.1A 2010-12-23 2011-12-23 Adjustable anchor system and method CN103269647B (en)
US12/977146 2010-12-23
CN103269647A CN103269647A (en) 2013-08-28
CN103269647B true CN103269647B (en) 2017-09-12
CN201110460434.6A CN102525583B (en) 2010-12-23 2011-12-23 Adjustable anchor system and method
EP (2) EP2468194B1 (en)
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2010-12-23 US US12/977,146 patent/US8821543B2/en active Active
2011-12-15 CA CA 2762250 patent/CA2762250A1/en not_active Abandoned
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2011-12-23 EP EP11806122.5A patent/EP2654576A2/en active Pending
2014-07-31 US US14/448,812 patent/US8974495B2/en active Active
CN103269647A (en) 2013-08-28
BRPI1106765A2 (en) 2015-07-28
CA2822861A1 (en) 2012-06-28
BR112013018333A2 (en) 2018-09-04
AU2011348045A1 (en) 2013-07-18
JP2012130705A (en) 2012-07-12
EP2468194B1 (en) 2019-02-13
EP2654576A2 (en) 2013-10-30
JP6045789B2 (en) 2016-12-14
JP2014510548A (en) 2014-05-01
AU2011254063B2 (en) 2016-08-11
EP2468194A3 (en) 2012-11-14
JP6147671B2 (en) 2017-06-14
AU2011254063A1 (en) 2012-07-12
AU2011348045B2 (en) 2016-07-28
US8821543B2 (en) 2014-09-02
CN102525583B (en) 2016-02-03
US8974495B2 (en) 2015-03-10
US20120165864A1 (en) 2012-06-28
EP2468194A2 (en) 2012-06-27
US20140343606A1 (en) 2014-11-20
CN102525583A (en) 2012-07-04
CA2762250A1 (en) 2012-06-23