Source: http://www.google.com/patents/US5232459?dq=6,928,433
Timestamp: 2014-03-11 14:16:21
Document Index: 145538336

Matched Legal Cases: ['art. 3', 'art 1', 'art 2', 'art 1', 'art 2', 'art 2', 'art 2', 'arts 1']

Patent US5232459 - Multi-dose syringe - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsA prefilled syringe including a vial containing a measured quantity of an injectable product is provided Adjacent an end the vial is a displaceable wall adapted to be urged by plunger means so as to expel the product from the vial through a needle. The syringe also includes a two part housing for the...http://www.google.com/patents/US5232459?utm_source=gb-gplus-sharePatent US5232459 - Multi-dose syringeAdvanced Patent SearchPublication numberUS5232459 APublication typeGrantApplication numberUS 07/720,843PCT numberPCT/EP1990/000014Publication dateAug 3, 1993Filing dateJan 4, 1990Priority dateJan 13, 1989Fee statusLapsedAlso published asDE69001904D1, DE69001904T2, EP0378305A1, EP0378305B1, EP0453490A1, WO1990007946A1Publication number07720843, 720843, PCT/1990/14, PCT/EP/1990/000014, PCT/EP/1990/00014, PCT/EP/90/000014, PCT/EP/90/00014, PCT/EP1990/000014, PCT/EP1990/00014, PCT/EP1990000014, PCT/EP199000014, PCT/EP90/000014, PCT/EP90/00014, PCT/EP90000014, PCT/EP9000014, US 5232459 A, US 5232459A, US-A-5232459, US5232459 A, US5232459AInventorsBirger T. Y. HjertmanOriginal AssigneeKabi Pharmacia AbExport CitationBiBTeX, EndNote, RefManPatent Citations (16), Referenced by (24), Classifications (21), Legal Events (6) External Links: USPTO, USPTO Assignment, EspacenetMulti-dose syringeUS 5232459 AAbstract A prefilled syringe including a vial containing a measured quantity of an injectable product is provided Adjacent an end the vial is a displaceable wall adapted to be urged by plunger means so as to expel the product from the vial through a needle. The syringe also includes a two part housing for the vial and the plunger. One of the housing parts includes a stop surface that cooperates with a pair of corresponding surfaces extending from an external surface of the plunger. The plunger stop surfaces are positioned on opposite sides of the housing part stop surface to limit the displacement of the plunger within the vial. The position of the stop surfaces on the plunger relative to the vial may be varied by rotating the threadably connected housing parts relative to each other. A click-stop mechanism provided with the housing parts permits the housing parts to be rotated relative to each other in predetermined increments. A graduated dosing ring may be rotatably mounted about the housing parts. The dosing ring may be coaxial with and rotatable relative to the housing parts and includes means to cooperate with the click-stop mechanism.
I claim: 1. A prefilled syringe comprising:a vial containing a measured quantity of an injectable product, said vial having adjacent a first end thereof a fixed wall, said fixed wall including means for receiving a hollow needle providing an opening into said vial, said vial having adjacent its second opposite end a displaceable wall urged toward said fixed wall by a plunger means so as to expel said product from said vial and through said needle said second end including an opening for receiving said plunger means; a housing for said vial and said plunger including two threadably connectable housing parts, one of said housing parts including a stop surface extending inward from an inner surface and cooperating with a pair of corresponding surfaces extending from an external surface of said plunger, one of said plunger stop surfaces being positioned on each side of said housing part stop surface to limit the displacement of said plunger within said vial, whereby the position of said stop surfaces on said plunger relative to said vial may be varied by rotating said threadably connected housing parts relative to each other; a click-stop mechanism provided with said two housing parts permits rotation of said two housing parts relative to each other in predetermined increments; a graduated dosing ring rotatably mounted about said two housing parts, said dosing ring being coaxial with and rotatable relative to said two housing parts, said dosing ring including means to cooperate with said click-stop mechanism. 2. The syringe according to claim 1 wherein said two housing parts include a first outer housing part having adjacent a first end thereof a wall and adjacent its second opposite end an opening to receive a second part, said vial, and said plunger means, said first outer housing part also including an inner threaded surface;said housing also including a second inner housing part including adjacent a first end thereof an externally threaded connection, said threaded connection engaging said inner threaded surface of said first outer housing part, said second inner housing part including said stop surface extending inward from an inner surface adjacent a second opposite end of said second part. 3. The syringe according to claim 1, wherein said click-stop mechanism includes a plurality of detents formed on a surface of one of said housing parts and parallel to a major axis of said housing part, whereby said protrusion engages said surface of said housing part.
BEST AND VARIOUS MODES FOR CARRYING OUT INVENTION The syringe comprises a first, outer, cylindrical housing part 1 and a second, inner, cylindrical housing part 2. The first housing part 1 has an end wall 9 and has internal screw-threading 3 over a part of its whole length and the second housing part 2 has an externally threaded end 4 mating with the threading 3 on the first housing part. The inner housing part 2 has an end wall 8. The inner housing part 2 acts as a housing for a plunger rod 5 having an operating handle 6 at one end. The plunger rod 5 has an integral stop 7 spaced from the handle 6 and both the stop 7 and the inner surface of the handle 6 co-operate with the end wall to limit the travel of the plunger rod 5. The other end wall 9 of the outer housing portion is externally threaded and of reduced cross-section to receive a corresponding internally-threaded needle holder 16 provided with a hypodermic needle 10. A glass phial 11 is housed within the outer and inner housing parts 1, 2. This phial has a necked first end 12 closed by a pierced elastomeric bung 13 through which the needle passes, forming a seal. The other end 22 of the phial 11 is open and receives the plunger rod 5. The plunger rod 5 co-operates with an elastomeric piston member 14 which is slidable within the phial 11 and forms a fluid-tight seal with the inner wall thereof. The space within the phial between the piston member 14 and the bung 13 is filled with a solution of a drug 15 such as heparin.
BRIEF DESCRIPTION OF THE DRAWINGS One disposable syringe embodying the invention for administration of two equal doses of an injectable drug will now be described with reference to the accompanying drawings in which:
FIELD OF THE INVENTION This invention relates to a pre-filled multi-dose syringe for example for the administration by injection of a drug or other pharmaceutical product. It may take various forms; for example it may be generally in the shape of a fountain-pen, or in the shape of a conventional syringe,
BACKGROUND OF THE INVENTION The invention particularly relates to such a syringe which is constructed relatively inexpensively and is therefore intended to be discarded when the product with which it has been filled has been exhausted.
SUMMARY OF THE INVENTION The multi-dose syringe of this invention is relatively simple in construction and does not involve potentially unreliable ratchet mechanisms. It incorporates an in-built dosing ring to assist in metering the dose to be injected and does not require premature removal of the protective cap for the needle.
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KleymanDosage deviceUS6673035Oct 20, 2000Jan 6, 2004Antares Pharma, Inc.Medical injector and medicament loading system for use therewithUS7341575Dec 23, 2003Mar 11, 2008Antares Pharma, Inc.Medical injector and medicament loading system for use therewithUS7867197Mar 29, 2006Jan 11, 2011The General Hospital CorporationSingle-dose syringe driverUS7905352Aug 8, 2005Mar 15, 2011Washington Biotech CorporationKits containing medicine injection devices and containersUS7927303Oct 9, 2007Apr 19, 2011Washington Biotech CorporationMedicine injection devices and methodsUS7931618Oct 31, 2007Apr 26, 2011Washington Biotech CorporationApparatuses and methods for injecting medicines to a desired depthUS8187224Sep 29, 2009May 29, 2012Washington Biotech CorporationMethods performed by medicine injection apparatusesUS8231576Dec 20, 2010Jul 31, 2012The General Hospital CorporationSingle-dose syringe driverUS8366682Mar 4, 2009Feb 5, 2013Washington Biotech CorporationMedicine injection apparatusesUS20110230827 *Nov 22, 2010Sep 22, 2011Kevin MoriMixing device for a two-chamber ampouleWO2001019428A2Sep 13, 2000Mar 22, 2001Vitro Diagnostics IncMulti-dose syringe driver* Cited by examinerClassifications U.S. Classification604/208, 604/218, 604/211, 604/232International ClassificationA61M5/32, A61M5/31, A61M5/315, A61M5/24Cooperative ClassificationA61M5/3202, A61M5/3158, A61M2005/2407, A61M5/31551, A61M5/31593, A61M5/31561, A61M5/31563, A61M2005/2488, A61M5/31525, A61M5/24European ClassificationA61M5/315E2B6, A61M5/315E2B1A, A61M5/24Legal EventsDateCodeEventDescriptionSep 27, 2005FPExpired due to failure to pay maintenance feeEffective date: 20050803Aug 3, 2005LAPSLapse for failure to pay maintenance feesFeb 16, 2005REMIMaintenance fee reminder mailedJan 11, 2001FPAYFee paymentYear of fee payment: 8Jan 21, 1997FPAYFee paymentYear of fee payment: 4Jul 16, 1992ASAssignmentOwner name: KABI PHARMACIA AB, SWEDENFree format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:HJERTMAN, BIRGER T.Y.;REEL/FRAME:006206/0099Effective date: 19920520RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google