Source: http://www.google.com/patents/US8083767?dq=7253017
Timestamp: 2014-07-24 21:06:34
Document Index: 523701844

Matched Legal Cases: ['Application No. 08011884', 'Application No. 180497', 'Application No. 179173', 'Application No. 180497', 'Application No. 179173', 'Application No. 2007', 'Application No. 05787529', 'Application No. 2007', 'Application No. 2008', 'Application No. 200580023327', 'Application No. 2005272102', 'Application No. 2005800293656', 'Application No. 2006800252468', 'Application No. 2006247355', 'Application No. 179173', 'Application No. 180497', 'Application No. 2006800252468', 'Application No. 2005800293656']

Patent US8083767 - Access and closure device and method - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign in<nobr>Advanced Patent Search</nobr>PatentsDevices and methods for accessing and closing vascular sites are disclosed. Self-sealing closure devices and methods are disclosed. A device that can make both steeply sloping and flat access paths into a vascular lumen is disclosed. The device can also form arteriotomies with sections cleaved between...http://www.google.com/patents/US8083767?utm_source=gb-gplus-sharePatent US8083767 - Access and closure device and methodAdvanced Patent SearchPublication numberUS8083767 B2Publication typeGrantApplication numberUS 11/544,317Publication dateDec 27, 2011Filing dateOct 6, 2006Priority dateMay 12, 2005Also published asCA2607387A1, CN101217916A, CN101217916B, CN103190942A, EP1885260A2, US8002794, US8241325, US20060271078, US20070106246, US20070255313, US20090318889, WO2006124896A2, WO2006124896A3Publication number11544317, 544317, US 8083767 B2, US 8083767B2, US-B2-8083767, US8083767 B2, US8083767B2InventorsD. Bruce ModesittOriginal AssigneeArstasis, Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (108), Non-Patent Citations (82), Classifications (21), Legal Events (1) External Links: USPTO, USPTO Assignment, EspacenetAccess and closure device and methodUS 8083767 B2Abstract Devices and methods for accessing and closing vascular sites are disclosed. Self-sealing closure devices and methods are disclosed. A device that can make both steeply sloping and flat access paths into a vascular lumen is disclosed. The device can also form arteriotomies with sections cleaved between a vessel's intima and adventitia. Methods for using the device are also disclosed.
1. A method for forming a tract in a tissue wall using a device comprising an anchor having an anchor longitudinal axis and an introduction device having an introduction longitudinal axis that forms an introduction angle with the anchor longitudinal axis, the method comprising:
advancing the anchor at a first angle into a lumen defined by the tissue wall;
introducing the introduction device through the tissue wall and through a proximal extension of the anchor;
advancing the introduction device into the lumen to create a tract through the tissue wall, the tract including at least two sloped regions, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 30� and is different than the first angle; and
advancing an introducer sheath into the tract to expand the tract so that a procedure may
be performed therethrough, wherein after the procedure has been performed and the introduction device has been withdrawn from the tract, blood pressure acting on the tissue wall causes first and second opposed tissue portions defining the tract to contact each other and self-seal.
2. The method of claim 1, wherein the tract has a noncircular cross-section.
3. The method of claim 1, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 19�.
4. The method of claim 1, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 15�.
5. The method of claim 1, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 5� to about 10�.
6. The method of claim 1, wherein when the introduction device enters the lumen, the introduction angle has an absolute value of about 10�.
7. The method of claim 1, further comprising using the anchor to stabilize the device with respect to the tissue wall.
8. The method of claim 1, further comprising positioning the anchor within the lumen so that the anchor is in contact with the tissue wall.
9. The method of claim 1, wherein the tract includes at least one substantially flat region.
10. The method of claim 9, wherein the tract includes at least two substantially flat regions.
11. A method for forming a tract in a tissue wall using a device comprising an anchor having an anchor longitudinal axis and an introduction device having an introduction longitudinal axis that forms an introduction angle with the anchor longitudinal axis, the method comprising:
advancing the anchor at a first angle into a lumen defined by the tissue wall through a first arteriotomy;
introducing the introduction device into the tissue wall and through a proximal extension of the anchor, and advancing the introduction device through the tissue wall and into the lumen through a second arteriotomy, so that the introduction device creates a tract through the tissue wall, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 30� and is different than the first angle; and
advancing an introducer sheath into the tract to expand the tract so that a procedure may be performed therethrough, wherein the device further comprises a pressure check port and a sensor in fluid communication with the pressure check port, and wherein after the procedure has been performed and the introduction device has been withdrawn from the tract, blood pressure acting on the tissue wall causes first and second opposed tissue portions defining the tract to contact each other and self-seal.
12. The method of claim 11, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 19�.
13. The method of claim 11, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 15�.
14. The method of claim 11, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 5� to about 10�.
15. The method of claim 11, wherein when the introduction device enters the lumen, the introduction angle has an absolute value of about 10�.
16. The method of claim 11, further comprising using the anchor to stabilize the device with respect to the tissue wall.
17. The method of claim 11, further comprising positioning the anchor within the lumen so that the anchor is in contact with the tissue wall.
18. The method of claim 11, further comprising advancing the introduction device into the lumen until the sensor provides a signal that the pressure check port has entered the lumen.
19. The method of claim 18, wherein the sensor provides a signal that the pressure check port has entered the lumen by displaying blood flow.
20. The method of claim 18, further comprising withdrawing the introduction device from the lumen until the sensor no longer provides a signal.
21. The method of claim 11, wherein the device comprises one or more radiopaque markers.
22. The method of claim 21, wherein the first introducer comprises a radiopaque marker.
23. The method of claim 21, further comprising viewing the device using fluoroscopy.
24. A method for forming a tract in a tissue wall using a device comprising an anchor having an anchor longitudinal axis and an introduction device having an introduction longitudinal axis that forms an introduction angle with the anchor longitudinal axis, the method comprising:
introducing the introduction device into the tissue wall and through a proximal extension of the anchor;
traversing the introduction device through the tissue wall to form a tract in the tissue wall and to enter the lumen, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 30� and is different than the first angle; and
advancing an introducer sheath into the tract to expand the tract so that a procedure may be performed therethrough, wherein the tract includes at least two sloped regions, and wherein after the procedure has been performed and the introduction device has been withdrawn from the tract, blood pressure acting on the tissue wall causes first and second opposed tissue portions defining the tract to contact each other and self-seal.
25. The method of claim 24, wherein the tract has a noncircular cross-section.
26. The method of claim 24, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 19�.
27. The method of claim 24, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 15�.
28. The method of claim 24, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 5� to about 10�.
29. The method of claim 24, wherein when the introduction device enters the lumen, the introduction angle has an absolute value of about 10�.
30. The method of claim 24, further comprising using the anchor to stabilize the device with respect to the tissue wall.
31. The method of claim 24, further comprising positioning the anchor within the lumen so that the anchor is in contact with the tissue wall.
32. The method of claim 24, wherein the tract includes at least one substantially flat region.
33. The method of claim 32, wherein the tract includes at least two substantially flat regions.
34. A method for forming a self-sealing arteriotomy using a device comprising an anchor having an anchor longitudinal axis and an introduction device having an introduction longitudinal axis that forms an introduction angle with the anchor longitudinal axis, the method comprising:
introducing the anchor at a first angle through an artery wall into a lumen of the artery;
introducing the introduction device into the artery wall and through a proximal extension of the anchor to form a tract within the artery wall;
advancing the introduction device into the lumen of the artery, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 30� and is different than the first angle; and
advancing an introducer sheath into the tract to expand the tract so that a procedure may be performed therethrough, wherein the tract includes at least two sloped regions, and wherein after the procedure has been performed and the introduction device has been withdrawn from the tract, blood pressure acting on the artery wall causes first and second opposed tissue portions defining the tract to contact each other and self-seal.
35. The method of claim 34, wherein the tract has a noncircular cross-section.
36. The method of claim 34, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 19�.
37. The method of claim 34, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 0� to about 15�.
38. The method of claim 34, wherein when the introduction device enters the lumen, the introduction angle has an absolute value from about 5� to about 10�.
39. The method of claim 34, wherein when the introduction device enters the lumen, the introduction angle has an absolute value of about 10�.
40. The method of claim 34, further comprising using the anchor to stabilize the device with respect to the artery wall.
41. The method of claim 34, further comprising positioning the anchor within the lumen so that the anchor is in contact with the artery wall.
42. The method of claim 34, wherein the tract includes at least one substantially flat region.
43. The method of claim 42, wherein the tract includes at least two substantially flat regions. Description
CROSS-REFERENCE TO RELATED APPLICATION This application is a continuation of U.S. Ser. No. 11/432,982, filed May 12, 2006, which claims the benefit under 35 U.S.C. �119(e) of Provisional Application 60/680,388, filed on May 12, 2005, both of which are hereby incorporated by reference in their entirety.
After hemostasis is achieved by manual compression, the patient is required to remain recumbent for six to eighteen hours under observation to assure continued hemostasis. During this time bleeding from the vascular access wound can restart potentially resulting in major complications. These complications may require blood transfusion and/or surgical intervention.
Bioabsorbable fasteners have also been used to stop bleeding. Generally, these approaches rely on the placement of a thrombogenic and bioabsorbable material, such as collagen, at the superficial arterial wall over the puncture site. This method generally presents difficulty locating the interface of the overlying-tissue and the adventitial surface of the blood vessel. Implanting the fastener too far from the desired location can result in failure to provide hemostasis. If, however, the fastener intrudes into the vascular lumen, thrombus can form on the fastener. Thrombus can embolize downstream and/or block normal blood flow at the thrombus site. Implanted fasteners can also cause infection and auto-immune reactions/rejections of the implant.
Due to the deficiencies of the above methods and devices, a need exists for a more reliable vascular closure-method and device. There also exists a need for a vascular closure device and method that is self-sealing and secure. There also exists a need for a vascular closure device and method requiring no or few extra steps to close the vascular site.
BRIEF SUMMARY OF THE INVENTION A method for accessing a biological lumen having a lumen wall and surrounding tissue is disclosed. The method includes forming a path between the lumen wall and the surrounding tissue. The method further includes extending the path through the lumen wall. The method also includes opening the path to the lumen.
The relaxed configuration of the introduction device can have a second bend at a second end of the first slope, a second fiat section extending at a first end from the second bend, a third bend at a second end of the second flat section, and a second slope extending from the third bend. The access device can have a delivery guide. The delivery guide can be configured to deliver the introduction device.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is an embodiment of a method of using the arteriotomy device in a cross-section of a lumen.
FIGS. 28 through 32 illustrate various embodiments of cross-section I-I of FIG. 27.
DETAILED DESCRIPTION U.S. patent application Ser. No. 10/844,247, filed 12 May 2004, is incorporated by reference herein in its entirety. Aspects, characteristics, components or complete embodiments of devices and methods disclosed therein can be used with anything disclosed herein.
FIGS. 1 through 6 illustrate embodiments of an arteriotomy device 2, and methods for accessing (e.g., percutaneously) a biological lumen 4 and deploying an introduction device 6 that can have one or more pre-formed bends. The biological lumen 4 can be surrounded by a lumen wall 8 (e.g., intima and/or media). The lumen wall 8 can be surrounded by surrounding tissue 10 (e.g., media and/or adventitia).
The arteriotomy device 2 can have a delivery guide 12. The delivery guide 12 can be slidably attached to an anchor 14. The anchor 14 can be rigid, flexible or combinations thereof. The anchor 14 can be resilient, deformable or combinations thereof. The anchor 14 can be retractable and extendable from the delivery guide 12. The anchor 14 can have a guide eye sheath or an attachable guidewire. The anchor 14 can have an integral, or multiple separate and fixedly attached, wound wire. The anchor 14 can have a wire coating, for example a lubricious coating and/or a coating made from urethane
Any or all elements of the arteriotomy device 2 or other devices or apparatuses described herein can be made from, for example, a single or multiple stainless steel alloys, nickel titanium alloys (e.g., Nitinol), cobalt-chrome alloys (e.g., ELGILOY� from Elgin Specialty Metals, Elgin, Ill.; CONICHROME� from Carpenter Metals Corp., Wyomissing, Pa.), molybdenum alloys (e.g., molybdenum TZM alloy, for example as disclosed in International Pub. No. WO 03/082363 A2, published 9 Oct. 2003, which is herein incorporated by reference in its entirety), tungsten-rhenium alloys, for example, as disclosed in International Pub. No. WO 03/082363, polymers such as polyester (e.g., DACRBN� from E. I. Du Pont de Nemours and Company, Wilmington, Del.), carbon fiber composites (e.g., carbon fiber nylon composite, such as carbon fiber reinforced nylon 66), polypropylene, polytetrafluoroethylene (PTFE), expanded PTFE (ePTFE), polyether ether ketone (PEEK), nylon, polyether-block co-polyamide polymers (e.g., PEBAX� from ATOFINA, Paris, France), aliphatic polyether polyurethanes (e.g., TECOFLEX� from Thermedics Polymer Products, Wilmington, Mass.), polyvinyl chloride (PVC), polyurethane, thermoplastic, fluorinated ethylene propylene (FEP), absorbable or resorbable polymers such as polyglycolic acid (PGA), polylactic acid (PLA), polydioxanone, and pseudo-polyamino tyrosine-based acids, extruded collagen, silicone, zinc, echogenic, radioactive, radiopaque materials or combinations thereof. Examples of radiopaque materials are barium sulfate, zinc oxide, titanium, stainless steel, nickel-titanium alloys, tantalum and gold.
The elements of the arteriotomy device 2 and/or the filler and/or the fabric can be filled and/or coated with an agent delivery matrix known to one having ordinary skill in the art and/or a therapeutic and/or diagnostic agent. The agents within these matrices can include radioactive materials; radiopaque materials; cytogenic agents; cytotoxic agents; cytostatic agents; thrombogenic agents, for example polyurethane, cellulose acetate polymer mixed with bismuth trioxide, and ethylene vinyl alcohol; lubricious, hydrophilic materials; phosphor cholene; anti-inflammatory agents, for example non-steroidal anti-inflammatories (NSAIDs) such as cyclooygenase-1 (COX-1) inhibitors (e.g., acetylsalicylic acid, for example ASPIRIN� from Bayer AG, Leverkusen, Germany; ibuprofen, for example ADVIL� from Wyeth, Collegeville, Pa.; indomethacin; mefenamic acid), COX-2 inhibitors (e.g., VIOXX� from Merck & Co., Inc., Whitehouse Station, N.J.; CELEBREX� from Pharmacia Corp., Peapack, N.J.; COX-1 inhibitors); immunosuppressive agents, for example Sirolimus (RAPAMUNE�, from Wyeth, Collegeville, Pa.), or matrix metalloproteinase (M) inhibitors (e.g., tetracycline and tetracycline derivatives) that act early within the pathways of an inflammatory response. Examples of other agents are provided in Walton et al, Inhibition of Prostoglandin E2 Synthesis in Abdominal Aortic Aneurysms, Circulation, Jul. 6, 1999, 48-54; Tambiah et al, Provocation of Experimental Aortic Inflammation Mediators and Chlamydia pneumoniae, Brit. J. Surgery 88 (7), 935-940; Franklin et al, Uptake of Tetracycline by Aortic Aneurysm Wall and Its Effect on Inflammation and Proteolysis, Brit. J Surgery 86 (6), 771-775; Xu et al, Sp1 Increases Expression of Cyclooxygenase-2 in Hypoxic Vascular Endothelium, J. Biological Chemistry 275 (32) 24583-24589; and Pyo et al, Targeted Gene Disruption of Matrix Metalloproteinase-9 (Gelatinase B) Suppresses Development of Experimental Abdominal Aortic Aneurysms, J. Clinical Investigation 105 (11), 1641-1649 which are all incorporated by reference in their entireties.
When the anchor 14 is properly located in the lumen 4, the introduction device can be translated, as shown by arrow. The introduction device can form a second arteriotomy 28. The introduction device 6 can create a cleavage 30 between the lumen wall 8 and the surrounding tissue 10. The introduction device 6 can cleave a plane in the lumen wall 8, as shown in FIG. 2. The cleavage 30 and/or cleavage plane can be substantially parallel with a lumen wall surface 32. The introduction device 6 can be adjacent to the adventitia in a blood vessel. The introduction device 6 can be advanced along the subintimal or submedial cleavage plane in a blood vessel.
Once the lumen wall 8, and/or the surrounding tissue 10, and/or the cleavage has been cleaved, a subintimal angioplasty can be performed as known to one having ordinary skill in the art. Once the lumen wall 8, and/or the surrounding tissue 10, and/or the cleavage 30 has been cleaved, a remote endarterectomy can be performed as known to one having ordinary skill in the art.
FIG. 4 illustrates that the introduction device 6 can be further translated, as shown by arrow. The introduction-device 6 can enter the lumen 4.
FIG. 11 illustrates that the filler can be in the in the cleavage 30, not in the second arteriotomy 28. The filler 70 can exert filler pressure 72 against the second flat and/or first slope 64 and/or other sections of the second arteriotomy 28.
FIGS. 12 and 13 illustrate the arteriotomy device 2. The arteriotomy device can have a handle 74 that can be integral with or fixedly attached to a delivery guide extension 76. The delivery guide extension 76 can be integral with or fixedly attached to the delivery guide 12. The anchor 14 can extend from, and be slidably and/or fixedly attached to or integral with, the delivery guide 12.
The handle 74 can have a second control 1100. The second control 100 can be rotatably attached to the handle 74, for example at a control pivot 102. The second control 100 can have a tab 104. The tab 104 can be configured to be ergonomically receptive to be activated by a digit and/or a palm.
The handle 74 can have a third control 94. The third control can be slidably attached to the handle 74. The third control 94 can have or be a plunger. The third control 94 can have a press 106. The press 106 can be configured to be ergonomically receptive to be activated by a digit and/or a palm. The handle 74 can have one or more grips 108. The grips 108 can be configured to be ergonomically receptive to be heed by a digit and/or a palm.
The guidewire 46 can be used to deploy the arteriotomy device to a desired location in a lumen. The arteriotomy device 2 can be translated, for example percutaneously, over and along the guidewire 46. If the guidewire 46 is in a lumen, the arteriotomy device 2 can be translated along the guidewire 46, for example, until blood appears at the pressure check port
FIG. 17 illustrates that the luminal retainer 24 can be deployed, as shown by arrow, for example due to the activation of the first control 96. The luminal retainer 24 can have a first stressed configuration. The luminal retainer 24 can have a second relaxed configuration. The luminal retainer 24 can be in a relaxed of a stressed configuration prior to deployment. The luminal retainer 24 can be in a relaxed or a stressed configuration after deployment. The relaxed configuration of the luminal retainer 24 can be the deployed configuration of the luminal retainer 24.
The arteriotomy device 2 can be configured to deploy the introduction device 6 from the anchor 14 and/or the delivery guide 12 (as shown). The anchor 14 and/or delivery guide 12 can have the introduction lumen exit port 112. The introduction device can deploy through the introduction lumen exit port 112. The introduction device 6 can be a solid or hollow needle, or combinations thereof.
FIG. 30 illustrates that the luminal retainer can be pre-formed with a curvature 130. When the deployment force is applied, shown by arrow, the luminal retainer 24 can relax, if pre-stressed (e.g., heat-treated to a specific shape), and/or be forced into buckling into the anchor 14 across from the luminal retainer exit port 122. The luminal retainer 24 can then buckle and/or twist at the weakest point along the length, for example the curvature 130. The luminal retainer 24 can then exit through the luminal retainer exit port 122.
The elements of the arteriotomy device 2, and those of any other devices and components disclosed herein, can be directly attached by, for example, melting, screwing, gluing, welding or use of an interference fit or pressure fit such as crimping, snapping, or combining methods thereof. The elements can be integrated, for example, molding, die cutting, laser cutting, electrical discharge machining (EDM) or stamping from a single piece or material. Any other methods can be used as known to those having ordinary skill in the art.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS2857925Jun 30, 1955Oct 28, 1958Stopford Higginbotham RichardGround gripping ferrule for use on walking sticks, crutches and the likeUS3727614May 13, 1971Apr 17, 1973Merck & Co IncMultiple dosage inoculatorUS3730185Oct 29, 1971May 1, 1973Cook IncEndarterectomy apparatusUS4006747Apr 23, 1975Feb 8, 1977Ethicon, Inc.Surgical methodUS4744364 *Feb 17, 1987May 17, 1988Intravascular Surgical Instruments, Inc.Device for sealing percutaneous puncture in a vesselUS4774949Jun 14, 1983Oct 4, 1988Fogarty Thomas JDeflector guiding catheterUS4850960 *Jul 8, 1987Jul 25, 1989Joseph GrayzelDiagonally tapered, bevelled tip introducing catheter and sheath and method for insertionUS4890611Apr 5, 1988Jan 2, 1990Thomas J. FogartyEndarterectomy apparatus and methodUS4921484Jul 25, 1988May 1, 1990Cordis CorporationMesh balloon catheter deviceUS4955897Aug 22, 1988Sep 11, 1990Ship Arthur GTissue forcepsUS4962755Jul 21, 1989Oct 16, 1990Heart Tech Of Minnesota, Inc.Method for performing endarterectomyUS5183464May 17, 1991Feb 2, 1993Interventional Thermodynamics, Inc.Radially expandable dilatorUS5271415Jan 28, 1992Dec 21, 1993Baxter International Inc.Guidewire extension systemUS5304184Oct 19, 1992Apr 19, 1994Indiana University FoundationApparatus and method for positive closure of an internal tissue membrane openingUS5336221Nov 6, 1992Aug 9, 1994Premier Laser Systems, Inc.Method and apparatus for applying thermal energy to tissue using a clampUS5358507Dec 15, 1992Oct 25, 1994Pat O. DailyThromboendarterectomy suction dissectorUS5364359Mar 1, 1991Nov 15, 1994Advanced Protective Injection Systems Medical B.V.Syringe with retractable needleUS5364389 *Nov 25, 1992Nov 15, 1994Premier Laser Systems, Inc.Method and apparatus for sealing and/or grasping luminal tissueUS5368601Apr 30, 1992Nov 29, 1994Lasersurge, Inc.Trocar wound closure deviceUS5380290Apr 16, 1992Jan 10, 1995Pfizer Hospital Products Group, Inc.Body access deviceUS5383897Dec 10, 1993Jan 24, 1995Shadyside HospitalMethod and apparatus for closing blood vessel puncturesUS5391182Aug 3, 1993Feb 21, 1995Origin Medsystems, Inc.Apparatus and method for closing puncture woundsUS5391183Aug 16, 1991Feb 21, 1995Datascope Investment CorpDevice and method sealing puncture woundsUS5403329Mar 21, 1994Apr 4, 1995United States Surgical CorporationInstrument for closing trocar puncture woundsUS5415657Oct 13, 1992May 16, 1995Taymor-Luria; HowardPercutaneous vascular sealing methodUS5417699Dec 10, 1992May 23, 1995Perclose IncorporatedDevice and method for the percutaneous suturing of a vascular puncture siteUS5437665Oct 12, 1993Aug 1, 1995Munro; Malcolm G.Electrosurgical loop electrode instrument for laparoscopic surgeryUS5439469Nov 5, 1993Aug 8, 1995Advanced Surgical, Inc.Wound closure deviceUS5451230Oct 11, 1994Sep 19, 1995Steinert; Roger F.Cataract disassemblyUS5462561Aug 5, 1993Oct 31, 1995Voda; Jan K.For suturing a perforation in a side wall of a patient's blood vesselUS5467786May 16, 1994Nov 21, 1995William C. AllenMethod for repairing tears and incisions in soft tissueUS5470338Oct 8, 1993Nov 28, 1995United States Surgical CorporationInstrument for closing trocar puncture woundsUS5474568Nov 24, 1993Dec 12, 1995United States Surgical CorporationInstrument for closing trocar puncture woundsUS5476470Apr 15, 1994Dec 19, 1995Fitzgibbons, Jr.; Robert J.Trocar site suturing deviceUS5489288Apr 4, 1994Feb 6, 1996Advanced Surgical, Inc.Device and method for applying large-diameter ligating loopUS5496332Oct 20, 1994Mar 5, 1996Cordis CorporationWound closure apparatus and method for its useUS5496334Mar 31, 1994Mar 5, 1996J. Stro/ bel & Sohne GmbH & Co.Suturing apparatusUS5503634Sep 27, 1993Apr 2, 1996Christy; William J.Surgical stab wound closure device and methodUS5507744 *Apr 30, 1993Apr 16, 1996Scimed Life Systems, Inc.Apparatus and method for sealing vascular puncturesUS5527321Jul 14, 1993Jun 18, 1996United States Surgical CorporationInstrument for closing trocar puncture woundsUS5527322Nov 8, 1993Jun 18, 1996Perclose, Inc.Device and method for suturing of internal puncture sitesUS5536255Oct 3, 1994Jul 16, 1996Moss; GeraldDilator/introducer apparatus for percutaneous gastrostomyUS5571169Jun 7, 1993Nov 5, 1996Endovascular Instruments, Inc.Method of restoring reduced/absent blood flow capacity to an arteryUS5613974Jun 1, 1994Mar 25, 1997Perclose, Inc.Suturing deviceUS5620461Jan 5, 1995Apr 15, 1997Muijs Van De Moer; Wouter M.Sealing deviceUS5622188Mar 13, 1995Apr 22, 1997Endovascular Instruments, Inc.Method of restoring reduced or absent blood flow capacity in an arteryUS5645566Sep 15, 1995Jul 8, 1997Sub Q Inc.Apparatus and method for percutaneous sealing of blood vessel puncturesUS5653717Aug 28, 1995Aug 5, 1997Urohealth Systems, Inc.Wound closure deviceUS5695504Feb 24, 1995Dec 9, 1997Heartport, Inc.Devices and methods for performing a vascular anastomosisUS5700273Jul 14, 1995Dec 23, 1997C.R. Bard, Inc.Wound closure apparatus and methodUS5709224Jun 7, 1995Jan 20, 1998Radiotherapeutics CorporationMethod and device for permanent vessel occlusionUS5746755Nov 15, 1995May 5, 1998Perclose, Inc.Method and device for providing hemostasis at vascular penetration sitesUS5762066May 22, 1995Jun 9, 1998Ths International, Inc.Multifaceted ultrasound transducer probe system and methods for its useUS5766183Oct 21, 1996Jun 16, 1998Lasersurge, Inc.Vascular hole closureUS5772673Mar 7, 1996Jun 30, 1998United States Surgical CorporationApparatus for applying surgical clipsUS5779719Jun 14, 1994Jul 14, 1998Perclose, Inc.Device and method for the percutaneous suturing of a vascular puncture siteUS5792152Apr 26, 1996Aug 11, 1998Perclose, Inc.Device and method for suturing of internal puncture sitesUS5797929Nov 2, 1995Aug 25, 1998Perclose, Inc.Apparatus and methods for advancing surgical knotsUS5810810Jun 6, 1995Sep 22, 1998Scimed Life Systems, Inc.Apparatus and method for sealing vascular puncturesUS5817108May 19, 1997Oct 6, 1998Medtronic, Inc.Device and method for suturing woundUS5830232Apr 14, 1997Nov 3, 1998Hasson; Harrith M.Device for closing an opening in tissue and method of closing a tissue opening using the deviceUS5836955Jul 14, 1997Nov 17, 1998C.R. Bard, Inc.Wound closure apparatus and methodUS5846253Sep 19, 1996Dec 8, 1998C. R. Bard, Inc.For suturing a wound in a body wallUS5860990Aug 23, 1996Jan 19, 1999Nr Medical, Inc.Method and apparatus for suturingUS5860991Aug 22, 1997Jan 19, 1999Perclose, Inc.Method for the percutaneous suturing of a vascular puncture siteUS5868762Sep 25, 1997Feb 9, 1999Sub-Q, Inc.Percutaneous hemostatic suturing device and methodUS5882302Jun 24, 1996Mar 16, 1999Ths International, Inc.Methods and devices for providing acoustic hemostasisUS5902311Jun 15, 1995May 11, 1999Perclose, Inc.Low profile intraluminal suturing device and methodUS5921994Oct 7, 1997Jul 13, 1999Perclose, Inc.Low profile intraluminal suturing device and methodUS5941897May 9, 1997Aug 24, 1999Myers; Gene E.Energy activated fibrin plugUS5954732Sep 10, 1997Sep 21, 1999Hart; Charles C.Suturing apparatus and methodUS5972005Feb 17, 1998Oct 26, 1999Advanced Cardiovascular Systems, Ind.Wound closure assembly and method of useUS5972013Sep 19, 1997Oct 26, 1999Comedicus IncorporatedDirect pericardial access device with deflecting mechanism and methodUS5980539May 6, 1998Nov 9, 1999X-Site L.L.C.Device and method for suturing blood vessels and the likeUS5984917Oct 1, 1997Nov 16, 1999Ep Technologies, Inc.Device and method for remote insertion of a closed loopUS5984948May 21, 1998Nov 16, 1999Hasson; Harrith M.Device for closing an opening in tissue and method of closing a tissue opening using the deviceUS5984950Jul 20, 1998Nov 16, 1999Sub-Q, Inc.Percutaneous hemostasis deviceUS6033401Nov 3, 1997Mar 7, 2000Advanced Closure Systems, Inc.Vascular sealing device with microwave antennaUS6036699Mar 26, 1997Mar 14, 2000Perclose, Inc.Device and method for suturing tissueUS6036721May 17, 1999Mar 14, 2000Cap IncorporatedPuncture closureUS6042601Mar 18, 1998Mar 28, 2000United States Surgical CorporationApparatus for vascular hole closureUS6063085Oct 22, 1993May 16, 2000Scimed Life Systems, Inc.Apparatus and method for sealing vascular puncturesUS6071292Jun 28, 1997Jun 6, 2000Transvascular, Inc.Transluminal methods and devices for closing, forming attachments to, and/or forming anastomotic junctions in, luminal anatomical structuresUS6071300Jul 7, 1997Jun 6, 2000Sub-Q Inc.Apparatus and method for percutaneous sealing of blood vessel puncturesUS6077276Feb 17, 1999Jun 20, 2000X-Site L.L.C.sealing a puncture in a blood vessel; needle coupled to a suture is pushed from a needle retention channel formed within the proximal part through the tissue received in the gap and into a needle receiving channel formed within the distal partUS6080175Jul 29, 1998Jun 27, 2000Corvascular, Inc.Surgical cutting instrument and method of useUS6093173Sep 9, 1998Jul 25, 2000Embol-X, Inc.Introducer/dilator with balloon protection and methods of useUS6117144Jan 14, 1999Sep 12, 2000Sutura, Inc.Suturing device and method for sealing an opening in a blood vessel or other biological structureUS6117145Oct 16, 1997Sep 12, 2000Perclose, Inc.Method and device for providing hemostasis at vascular penetration sitesUS6136010Mar 4, 1999Oct 24, 2000Perclose, Inc.Articulating suturing device and methodUS6139560Mar 16, 1999Oct 31, 2000Kremer; Frederic B.Cutting device and method for making controlled surgical incisionsUS6143004Aug 18, 1998Nov 7, 2000Atrion Medical Products, Inc.Suturing deviceUS6146397Apr 6, 1999Nov 14, 2000Harkrider, Jr.; William W.Endarterectomy loopUS6152918Apr 9, 1998Nov 28, 2000Eclipse Surgical Technologies, Inc.Laser device with auto-piercing tip for myocardial revascularization proceduresUS6159232Dec 15, 1998Dec 12, 2000Closys CorporationClotting cascade initiating apparatus and methods of use and methods of closing woundsUS6171317Sep 14, 1999Jan 9, 2001Perclose, Inc.Knot tying device and methodUS6179832Aug 21, 1998Jan 30, 2001Vnus Medical Technologies, Inc.Expandable catheter having two sets of electrodesUS6190396Sep 14, 1999Feb 20, 2001Perclose, Inc.Device and method for deploying and organizing sutures for anastomotic and other attachmentsUS6197042Jan 5, 2000Mar 6, 2001Medical Technology Group, Inc.Vascular sheath with puncture site closure apparatus and methods of useUS6203554Nov 23, 1999Mar 20, 2001William RobertsApparatus, kit and methods for puncture site closureUS6206893Apr 8, 1998Mar 27, 2001Perclose, Inc.Device and method for suturing of internal puncture sitesUS6206895Oct 6, 1999Mar 27, 2001Scion Cardio-Vascular, Inc.Suture with toggle and delivery systemUS6245079Dec 23, 1999Jun 12, 2001Sutura, Inc.Suturing device and method for sealing an opening in a blood vessel or other biological structureUS6733515 *Mar 10, 1998May 11, 2004Neomend, Inc.Universal introducerUS6749621 *Feb 21, 2002Jun 15, 2004Integrated Vascular Systems, Inc.Sheath apparatus and methods for delivering a closure deviceUS6939363 *Jun 12, 2002Sep 6, 2005Radi Medical Systems AbClosure deviceUS20020156495 *Mar 25, 2002Oct 24, 2002Rodney BrennemanApparatus and method for percutaneous sealing of blood vessel puncturesUS20030158578 *Feb 21, 2002Aug 21, 2003Integrated Vascular Systems, Inc.Sheath apparatus and methods for delivering a closure device* Cited by examinerNon-Patent CitationsReference1European Search Report from European Patent Office for EP application No. EP05787529.6, Applicant Arstasis, Inc., EPO Forms 1507, 1503, and P0459, dated Nov. 5, 2010. (5 pages).2European Search Report mailed on Jun. 26, 2009, for EP Patent Application No. 08011884.7, filed on May 12, 2005, five pages.3File history for related U.S. Appl. No. 10/844,247, filed May 12, 2004, Inventor D. Bruce Modesitt.4File history for related U.S. Appl. No. 10/888,682, filed Jul. 10, 2004, Inventor D. Bruce Modesitt.5File history for related U.S. Appl. No. 11/432,982, filed May 12, 2006, Inventor D. Bruce Modesitt.6File history for related U.S. Appl. No. 11/544,149, filed Oct. 6, 2006, Inventor D. Bruce Modesitt.7File history for related U.S. Appl. No. 11/544,177, filed Oct. 6, 2006, Inventor D. Bruce Modesitt.8File history for related U.S. Appl. No. 11/544,196, filed Oct. 6, 2006, Inventor D. Bruce Modesitt.9File history for related U.S. Appl. No. 11/544,365, filed Oct. 6, 2006, Inventor D. Bruce Modesitt.10File history for related U.S. Appl. No. 11/545,272, filed Oct. 6, 2006, Inventor D. Bruce Modesitt.11File history for related U.S. Appl. No. 11/788,509, filed Apr. 19, 2007, Inventor D. Bruce Modesitt.12File history for related U.S. Appl. No. 11/873,957, filed Oct. 17, 2007, Inventor D. Bruce Modesitt, et al.13File history for related U.S. Appl. No. 12/467,251, filed May 15, 2009, Inventor D. Bruce Modesitt.14File history for related U.S. Appl. No. 12/507,038, filed Jul. 21, 2009, Inventor Michael Drews, et al.15File history for related U.S. Appl. No. 12/507,043, filed Jul. 21, 2009, Inventor Michael Drews, et al.16File history for related U.S. Appl. No. 12/693,395, filed Jan. 25, 2010, Inventor D. Bruce Modesitt.17File history for related U.S. Appl. No. 12/780,768, filed May 14, 2010, Inventor Michael Drews, et al.18File History for related U.S. Appl. No. 12/888,209, filed Sep. 22, 2010, Inventor D. Bruce Modesitt, et al.19File history for related U.S. Appl. No. 13/004,848, filed Jan. 11, 2011, Inventor D. Bruce Modesitt, et al.20Final Office Action for U.S. Appl. No. 11/873,957, Applicant Arstasis, Inc., dated May 4, 2011 (23 pages).21Final Office Action mailed Dec. 8, 2009, for U.S. Appl. No. 11/544,149, filed Oct. 6, 2006, 9 pages.22Final Office Action mailed on Aug. 21, 2009, for U.S. Appl. No. 11/788,509, filed Apr. 19, 2007, ten pages.23Final Office Action mailed on Jul. 6, 2009, for U.S. Appl. No. 10/844,247, filed May 12, 2004, nine pages.24Final Office Action mailed on Jun. 11, 2009, for U.S. Appl. No. 11/432,982, filed May 12, 2006, seven pages.25Final Office Action mailed on May 6, 2009, for U.S. Appl. No. 10/888,682, filed Jul. 10, 2004, eight pages.26Final Office Action mailed on Nov. 18, 2009, for U.S. Appl. No. 11/544,365, filed Oct. 6, 2006, 6 pages.27Final Office Action mailed on Nov. 25, 2009,for U.S. Appl. No. 11/544,177, filed Oct. 6, 2006, 8 pages.28Final Office Action mailed on Nov. 25, 2009,for U.S. Appl. No. 11/545,272, filed Oct. 6, 2006, 6 pages.29Final Office Action mailed on Nov. 27, 2009, for U.S. Appl. No. 11/544,196, filed Oct. 6, 2006, 6 pages.30Franklin, I.J. et al. (1999). "Uptake of Tetracycline by Aortic Aneurysm Wall and Its Effect on Inflammation and Proteolysis," Brit. J. Surgery 86(6):771-775.31Further Office Action dated May 24, 2010, for Israeli Patent Application No. 180497, with a filing date of May 12, 2005, with English translation provided by Israeli associate. (5 pages).32Further Office Action dated Sep. 6, 2010, for Israeli Patent Application No. 179173, with a filing date of Jun. 30, 2005, with English translation provided by Israeli associate. (9 pages).33Initial Office Action dated Jan. 24, 2010, for Israeli Patent Application No. 180497, with a filing date of May 12, 2005, with English translation provided by Israeli associate. (5 pages).34Initial Office Action dated Jan. 25, 2010, for Israeli Patent Application No. 179173, with a filing date of Jun. 30, 2005, with English translation provided by Israeli associate. (5 pages).35International Preliminary Report on Patentability issued on Mar. 3, 2009, for PCT Application No. PCT/US2005/023107, filed on Jun. 30, 2005, five pages.36International Preliminary Report on Patentability issued on Nov. 14, 2007, for PCT Application No. PCT/US2006/018915, filed on May 12, 2006, five pages.37International Preliminary Report on Patentability mailed on Mar. 5, 2009, for PCT Application No. PCT/US2005/016623, filed on May 12, 2005, five pages.38International Search Report mailed Aug. 8, 2008, for PCT Application No. PCT/US05/16623 filed May 12, 2005, three pages.39International Search Report mailed Jun. 5, 2008, for PCT Application No. PCT/US05/23107 filed Jun. 30, 2005, two pages.40International Search Report mailed on Sep. 3, 2009, for PCT Application No. PCT/US2009/051317, filed on Jul. 21, 2009, three pages.41Invitation to Pay Additional Fees mailed on Sep. 10, 2009, for PCT Application No. PCT/US09/51320, filed on Jul. 21, 2009, two pages.42Non-final office action dated May 28, 2011, for related U.S. Appl. No. 12/467,251, filed May 15, 2009, Inventor D. Bruce Modesitt, (11 pages).43Non-Final Office Action mailed Feb. 18, 2009, for U.S. Appl. No. 11/544,149, filed Oct. 6, 2006, 8 pages.44Non-Final Office Action mailed Feb. 18, 2009, for U.S. Appl. No. 11/545,272, filed Oct. 6, 2006, 7 pages.45Non-Final Office Action mailed Feb. 23, 2009, for U.S. Appl. No. 11/544,196, filed Oct. 6, 2006, 7 pages.46Non-Final Office Action mailed Feb. 23, 2009, for U.S. Appl. No. 11/544,365, filed Oct. 6, 2006, 6 pages.47Non-Final Office Action mailed Feb. 24, 2009, for U.S. Appl. No. 11/544,177, filed Oct. 6, 2006, 7 pages.48Non-Final Office Action mailed Jul. 31, 2008, for U.S. Appl. No. 10/888,682, filed Jul. 10, 2004, 12 pages.49Non-Final Office Action mailed Nov. 12, 2008, for U.S. Appl. No. 10/844,247, filed May 12, 2004, nine pages.50Non-Final Office Action mailed Oct. 29, 2008, for U.S. Appl. No. 11/788,509, filed Apr. 19, 2007, eight pages.51Non-Final Office Action mailed Oct. 8, 2008, for U.S. Appl. No. 11/432,982, filed May 12, 2006, seven pages.52Non-Final Office Action mailed on Apr. 15, 2010, for U.S. Appl. No. 11/432,982, filed May 12, 2006, eight pages.53Notice of Allowance mailed on Nov. 3, 2009, for U.S. Appl. No. 10/888,682, filed Jul. 10, 2004, nine pages.54Office Action dated Dec. 8, 2010, for Japanese Patent Application No. 2007-0520363, with a filing date of Jun. 30, 2005, and with English translation provided by Japanese associate, (5 pages).55Office Action dated Feb. 14, 2011, for European Patent Application No. 05787529.6, with a filing date of Jun. 30, 2005, (15 pages).56Office Action dated Jan. 24, 2011, for Japanese Patent Application No. 2007-513356, with a filing date of May 12, 2005, and with English translation provided by Japanese associate, (7 pages).57Office Action dated Jan. 24, 2011, for Japanese Patent Application No. 2008-123950, with a filing date of May 12, 2005, and with English translation provided by Japanese associate, (4 pages).58Office Action dated Jun. 3, 2010, for Chinese Patent Application No. 200580023327.X, with a filing date of May 12, 2005, with English translation provided by Chinese associate. (7 pages).59Office Action dated Jun. 4, 2010, for Australian Patent Application No. 2005272102, with a filing date of Jun. 30, 2005. (3 pages).60Office Action dated Jun. 4, 2010, for Chinese Patent Application No. 2005800293656, with a filing date of Jun. 30, 2005, with English translation provided by Chinese associate. (10 pages).61Office Action dated May 22, 2009, for Chinese Patent Application No. 2006800252468, with a filing date of May 12, 2006, with English translation provided by Chinese associate. (7 pages).62Office action for related AU Patent Application No. 2006247355, dated Mar. 16, 2011, (16 pages).63Office Action for U.S. Appl. No. 12/467,251, Applicant Arstasis Inc., dated Mar. 28, 2011 (20 pages).64Office Action from Related Application AU 20062473655, Applicant Arstasis, Inc., dated Mar. 21, 2011 (19 pages).65PCT International Preliminary Report on Patentability for PCT/US2009/051320, Applicant Arstasis, Inc., Forms PCT/IB/373 and PCT/ISA/237 dated Jan. 25, 2011. (7 pages).66PCT International Search Report and Written Opinion for PCT/ US2009/051320, Applicant Arstasis, Inc., Forms PCT/ISA/210, 220, and 237 dated Nov. 6, 2009. (11 pages).67PCT International Search Report and Written Opinion for PCT/ US2010/035001, Applicant Arstasis, Inc., Forms PCT/ISA/210, 220, and 237 dated Jul. 19, 2010. (11 pages).68PCT International Search Report and Written Opinion for PCT/ US2010/049859, Applicant Arstasis, Inc., Forms PCT/ISA/210, 220, and 237 dated Nov. 5, 2010. (14 pages).69PCT International Search Report and Written Opinion for PCT/US2011/020893, Applicant Arstasis, Inc., Forms PCT/ISA/210, 220, and 237, dated Apr. 19, 2011 (10 pages).70PCT/US06/18915 filed on May 12, 2006, 2 pages.71Pyo, R. et al. (Jun. 2000). "Targeted Gene Disruption of Matrix Metalloproteinase-9 (Gelatinase B) Suppresses Development of Experimental Abdominal Aortic Aneurysms," J. Clinical Investigation 105(11):1641-1649.72Response to Office Action submitted Jul. 13, 2010, for Israeli Patent Application No. 179173, with a filing date of Jun. 30, 2005. (1 page).73Response to Office Action submitted May 23, 2010, for Israeli Patent Application No. 180497, with a filing date of May 12, 2005, with English translation provided by Israeli associate. (7 pages).74Response to Office Action submitted Nov. 6, 2010, for Chinese Patent Application No. 2006800252468, with English instructions to respond provided to Chinese associate. (29 pages).75Response to Office Action submitted Oct. 18, 2010, for Chinese Patent Application No. 2005800293656, with English instructions to respond provided to Chinese associate, (27 pages).76Tambiah, J. et al. (2001). "Provocation of Experimental Aortic Inflammation and Dilatation by Inflammatory Mediators and Chlamydia pneumoniae," Brit. J. Surgery 88(7):935-940.77Walton, L.J. et al. (Jul. 6, 1999). "Inhibition of Prostaglandin E2 Synthesis in Abdominal Aortic Aneurysms," Circulation 100:48-54.78Written Opinion mailed on Aug. 20, 2007, for PCT Application No. PCT/US06/18915, filed on May 12, 2006, four pages.79Written Opinion mailed on Aug. 8, 2008, for PCT Application No. PCT/US05/16623 filed on May 12, 2005, three pages.80Written Opinion mailed on Jun. 5, 2008, for PCT Application No. PCT/US05/23107, filed on Jun. 30, 2005, four pages.81Written Opinion mailed on Sep. 3, 2009, for PCT Application No. PCT/US2009/051317, filed on Jul. 21, 2009, seven pages.82Xu, Q. et al. (Aug. 11, 2000). "Sp1 Increases Expression of Cyclooxygenase-2 in Hypoxic Vascular Endothelium," J. Biological Chemistry 275(32):24583-24589.Classifications U.S. Classification606/213, 606/215International ClassificationA61B17/08Cooperative ClassificationA61B17/3468, A61B17/3421, A61B17/3417, A61B17/32, A61B17/34, A61B2017/0065, A61B17/3403, A61B2017/00672, A61B17/0057, A61B2017/00676, A61B17/32093, A61B17/3415, A61B2017/00455, A61B2017/00637European ClassificationA61B17/34, A61B17/00P, A61B17/32, A61B17/3209FLegal EventsDateCodeEventDescriptionJan 5, 2007ASAssignmentOwner name: ARSTASIS, INC., CALIFORNIAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:MODESITT, D. BRUCE;REEL/FRAME:018715/0246Effective date: 20061106RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google