Source: http://www.google.com/patents/US8221327?dq=6734022
Timestamp: 2014-11-27 08:45:52
Document Index: 64972021

Matched Legal Cases: ['Application No. 08075738', 'Application No. 04784602', 'Application No. 04784602', 'Application No. 04784602', 'Application No. 04784602', 'art, 31']

Patent US8221327 - Therapy control based on cardiopulmonary status - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsMethods and systems provide an approach to therapy control based on assessment of a patient's cardiopulmonary status. Conditions sensed via sensors of an external respiratory therapy device are used to assess a patient's cardiopulmonary status. The respiratory therapy device sensors may be utilized alone...http://www.google.com/patents/US8221327?utm_source=gb-gplus-sharePatent US8221327 - Therapy control based on cardiopulmonary statusAdvanced Patent SearchPublication numberUS8221327 B2Publication typeGrantApplication numberUS 12/688,274Publication dateJul 17, 2012Filing dateJan 15, 2010Priority dateSep 18, 2003Also published asUS7662101, US20050065567, US20100174154Publication number12688274, 688274, US 8221327 B2, US 8221327B2, US-B2-8221327, US8221327 B2, US8221327B2InventorsKent Lee, Jeffrey E. Stahmann, Jesse W. Hartley, Quan NiOriginal AssigneeCardiac Pacemakers, Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (103), Non-Patent Citations (66), Classifications (35) External Links: USPTO, USPTO Assignment, EspacenetTherapy control based on cardiopulmonary statusUS 8221327 B2Abstract Methods and systems provide an approach to therapy control based on assessment of a patient's cardiopulmonary status. Conditions sensed via sensors of an external respiratory therapy device are used to assess a patient's cardiopulmonary status. The respiratory therapy device sensors may be utilized alone or in combination with other sensors to determine cardiopulmonary status of a patient. Therapy delivered to the patient is controlled based on the cardiopulmonary status assessment. For example, therapy delivered to the patient may be initiated, terminated, and/or modified based on the assessed cardiopulmonary status of the patient. Cardiopulmonary status assessment, therapy control, or both, are performed by an implantable device.
RELATED PATENT DOCUMENTS This application is a continuation of U.S. patent application Ser. No. 10/930,346, filed on Aug. 31, 2004, now U.S. Pat. No. 7,662,101, which claims the benefit of Provisional Patent Application Ser. No. 60/504,477 and 60/504,723, both filed on Sep. 18, 2003, to which Applicant claims priority under 35 U.S.C. �120 and 35 U.S.C. �119(e), respectively, and which are incorporated herein by reference in their entireties.
FIELD OF THE INVENTION The present invention relates generally to controlling therapy based on the cardiopulmonary status of a patient.
SUMMARY OF THE INVENTION Various embodiments of present invention involve methods and systems for controlling therapy based on the cardiopulmonary status of the patient. One embodiment of the invention involves a method for controlling a therapy delivered to a patient based on cardiopulmonary status. One or more physiological conditions are sensed using an external respiratory therapy device. The patient's cardiopulmonary status is assessed based on the sensed physiological conditions. Therapy delivered to the patient is controlled based on the patient's cardiopulmonary status. At least one of assessing the patient's cardiopulmonary status and controlling the therapy is performed at least in part implantably.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1A is a flowchart illustrating a method of determining a presence of a non-rhythm pulmonary disease and delivering therapy in accordance with embodiments of the invention;
The voltage signal developed at the impedance sense electrode 452 is proportional to the patient's transthoracic impedance and represents the patient's respiration waveform. The transthoracic impedance increases during respiratory inspiration and decreases during respiratory expiration. The transthoracic impedance may be used to determine the amount of air moved in one breath, denoted the tidal volume and/or the amount of air moved per minute, denoted the minute ventilation. A normal �at rest� respiration pattern, e.g., during non-REM sleep, includes regular, rhythmic inspiration�expiration cycles without substantial interruptions, as indicated in FIG. 7.
An example of how FIGS. 6A-6N may be used follows. Referring to FIGS. 6F-1 to 6G-2, the restrictive pulmonary disorder pneumoconiosis produces the physiological changes non-specific dyspnea (FIG. 6 F-1) and cough (FIG. 6G-1). Non-specific dyspnea (FIG. 6 F-1) and cough (FIG. 6G-1) are indicated by X or D marks in the column denoted pneumoconiosis in FIGS. 6F-1 and 6G-2, respectively. An �X� mark indicates that the symptom or physiological change may be derived from the sensed condition. A �D� mark indicates that the symptom or physiological change may be directly determined from the sensed condition. Non-specific dyspnea may be detected based on one or more of the conditions listed in the row for non-specific dyspnea illustrated in FIGS. 6B-1, 6B-3, and 6C-1. The conditions include duration of symptoms, abnormal breathing/coughing, blood pO2, inspiratory flow, expiratory flow, exhaled % CO2 and exhaled % O2, illustrated in FIG. 6C-1. The conditions also include arterial/venous pO2, blood pCO2, blood pO2, exhalation time, inspiration time, minute ventilation, tidal volume, respiration rate, FIG. 6B-3, and/or respiration sounds illustrated in FIG. 6B-1.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS4312734Feb 19, 1980Jan 26, 1982The Curators Of The University Of MissouriIon-selective electrodeUS4365636Jun 19, 1981Dec 28, 1982Medicon, Inc.Method of monitoring patient respiration and predicting apnea therefromUS4390405Jun 23, 1981Jun 28, 1983Curators Of The University Of MissouriReduction, polymeric coatingUS4562841Aug 5, 1982Jan 7, 1986Cardiac Pacemakers, Inc.Programmable multi-mode cardiac pacemakerUS4702253Oct 15, 1985Oct 27, 1987Telectronics N.V.Metabolic-demand pacemaker and method of using the same to determine minute volumeUS4721110Jul 24, 1985Jan 26, 1988Lampadius Michael SRespiration-controlled cardiac pacemakerUS4777962Feb 17, 1987Oct 18, 1988Respitrace CorporationMethod and apparatus for distinguishing central obstructive and mixed apneas by external monitoring devices which measure rib cage and abdominal compartmental excursions during respirationUS4802485Sep 2, 1987Feb 7, 1989Sentel Technologies, Inc.Sleep apnea monitorUS4807629Nov 19, 1987Feb 28, 1989Medtronic, Inc.Oxygen sensing pacemakerUS4813427Feb 17, 1987Mar 21, 1989Hellige GmbhApparatus and method for preventing hypoxic damageUS4827935Apr 24, 1986May 9, 1989Purdue Research FoundationDemand electroventilatorUS4830008Feb 16, 1988May 16, 1989Meer Jeffrey AMethod and system for treatment of sleep apneaUS4836219Jul 8, 1987Jun 6, 1989President & Fellows Of Harvard CollegeElectronic sleep monitor headgearUS4856524Aug 29, 1988Aug 15, 1989Intermedics, Inc.A-V responsive rate adaptive pacemakerUS4875477Jun 27, 1988Oct 24, 1989Dragerwerk AktiengesellschaftProtective mask having a built-in sensor for monitoring vital functionsUS4886064Nov 25, 1987Dec 12, 1989Siemens AktiengesellschaftBody activity controlled heart pacerUS4928688Jan 23, 1989May 29, 1990Mieczyslaw MirowskiMethod and apparatus for treating hemodynamic disfunctionUS4958632Mar 5, 1980Sep 25, 1990Medtronic, Inc.Adaptable, digital computer controlled cardiac pacemakerUS4961423Jul 15, 1988Oct 9, 1990Medtronic, Inc.Rate adaptive myoelectric pacerUS4982738Nov 30, 1988Jan 8, 1991Dr. Madaus GmbhDiagnostic apnea monitor systemUS5024222Feb 21, 1990Jun 18, 1991Siemens-Pacesetter, Inc.Dual chamberUS5036849Apr 4, 1990Aug 6, 1991Cardiac Pacemakers, Inc.Variable rate cardiac pacerUS5047930Jun 26, 1987Sep 10, 1991Nicolet Instrument CorporationMethod and system for analysis of long term physiological polygraphic recordingsUS5105354Jan 23, 1989Apr 14, 1992Nippon Kayaku Kabushiki KaishaMethod and apparatus for correlating respiration and heartbeat variabilityUS5123425Sep 6, 1990Jun 23, 1992EdentecObstructive sleep apnea collarUS5146918Mar 19, 1991Sep 15, 1992Medtronic, Inc.Demand apnea control of central and obstructive sleep apneaUS5174287May 28, 1991Dec 29, 1992Medtronic, Inc.Airway feedback measurement system responsive to detected inspiration and obstructive apnea eventUS5178156Jun 12, 1990Jan 12, 1993Chest CorporationApnea preventive stimulating deviceUS5183038Nov 4, 1991Feb 2, 1993The Trustees Of The University Of PennsylvaniaGated programmable ventilatorUS5187657Apr 5, 1990Feb 16, 1993Hewlett-Packard CompanyCardiac analyzer with rem sleep detectionUS5199424Dec 12, 1991Apr 6, 1993Sullivan Colin EDevice for monitoring breathing during sleep and control of CPAP treatment that is patient controlledUS5203348Jun 6, 1990Apr 20, 1993Cardiac Pacemakers, Inc.Body implantable tissue stimulating electrode assemblyUS5211173Sep 21, 1992May 18, 1993Medtronic, Inc.For treating obstructive sleep apneaUS5215082Apr 2, 1991Jun 1, 1993Medtronic, Inc.Implantable apnea generator with ramp on generatorUS5230337Jul 14, 1992Jul 27, 1993Cardiac Pacemakers, Inc.Process for implanting subcutaneous defibrillation electrodesUS5233983Sep 3, 1991Aug 10, 1993Medtronic, Inc.Method and apparatus for apnea patient screeningUS5243979Nov 15, 1991Sep 14, 1993Medtronic, Inc.Method and apparatus for implementing activity sensing in a pulse generatorUS5245995May 27, 1992Sep 21, 1993Rescare LimitedDevice and method for monitoring breathing during sleep, control of CPAP treatment, and preventing of apneaUS5259373Apr 9, 1992Nov 9, 1993Puritan-Bennett CorporationInspiratory airway pressure system controlled by the detection and analysis of patient airway soundsUS5275159Mar 20, 1992Jan 4, 1994Madaus Schwarzer Medizintechnik Gmbh & Co. KgMethod and apparatus for diagnosis of sleep disordersUS5280791Oct 19, 1992Jan 25, 1994The Sleep Disorders Diagnostic And Treatment Center, Ltd.Monitor system for determining the sleep stages of a personUS5284136May 13, 1991Feb 8, 1994Cardiac Pacemakers, Inc.Dual indifferent electrode pacemakerUS5299118Sep 5, 1991Mar 29, 1994Nicolet Instrument CorporationMethod and system for analysis of long term physiological polygraphic recordingsUS5301677Feb 6, 1992Apr 12, 1994Cardiac Pacemakers, Inc.Arrhythmia detector using delta modulated turning point morphology of the ECG waveUS5313953Jan 14, 1992May 24, 1994Incontrol, Inc.For monitoring the physiology of the human heartUS5334222Nov 3, 1992Aug 2, 1994Cardiac Pacemakers, Inc.Cardiac stimulating apparatus and method for heart failure therapyUS5335657May 3, 1991Aug 9, 1994Cyberonics, Inc.Therapeutic treatment of sleep disorder by nerve stimulationUS5353788Sep 21, 1992Oct 11, 1994Miles Laughton ECardio-respiratory control and monitoring system for determining CPAP pressure for apnea treatmentUS5360442Jan 4, 1993Nov 1, 1994Cardiac Pacemakers, Inc.Subcutaneous defibrillation electrodesUS5363842Dec 20, 1991Nov 15, 1994Circadian, Inc.Intelligent inhaler providing feedback to both patient and medical professionalUS5366496Apr 1, 1993Nov 22, 1994Cardiac Pacemakers, Inc.Subcutaneous shunted coil electrodeUS5376476Dec 6, 1993Dec 27, 1994Eylon; DanBattery orientation-indifferent battery receptorUS5388578Apr 6, 1993Feb 14, 1995Incontrol, Inc.Electrode system for use with an implantable cardiac patient monitorUS5391200Mar 10, 1994Feb 21, 1995Cardiac Pacemakers, Inc.Defibrillation patch electrode having conductor-free resilient zone for minimally invasive deploymentUS5397342Jun 7, 1993Mar 14, 1995Cardiac Pacemakers, Inc.Resilient structurally coupled and electrically independent electrodesUS5398682Nov 15, 1993Mar 21, 1995Lynn; Lawrence A.Method and apparatus for the diagnosis of sleep apnea utilizing a single interface with a human body partUS5404877Jun 4, 1993Apr 11, 1995Telectronics Pacing Systems, Inc.Leadless implantable sensor assembly and a cardiac emergency warning alarmUS5411031Nov 24, 1993May 2, 1995Incontrol, Inc.Implantable cardiac patient monitorUS5466245Nov 15, 1994Nov 14, 1995Cardiac Pacemakers, Inc.Method and apparatus to continuously optimize the A-V delay in a dual chamber pacemakerUS5483969Sep 21, 1994Jan 16, 1996Medtronic, Inc.Method and apparatus for providing a respiratory effort waveform for the treatment of obstructive sleep apneaUS5485851Sep 21, 1994Jan 23, 1996Medtronic, Inc.Method and apparatus for arousal detectionUS5487755Oct 25, 1994Jan 30, 1996Pacesetter, Inc.Methods for displaying a sequential series of pacing eventsUS5517983Dec 9, 1992May 21, 1996Puritan Bennett CorporationCompliance meter for respiratory therapyUS5520176Jun 23, 1993May 28, 1996Aequitron Medical, Inc.Iterative sleep evaluationUS5522382Jan 10, 1995Jun 4, 1996Rescare LimitedDevice and method for treating obstructed breathing having a delay/ramp featureUS5522862Sep 21, 1994Jun 4, 1996Medtronic, Inc.Method and apparatus for treating obstructive sleep apneaUS5540727Nov 15, 1994Jul 30, 1996Cardiac Pacemakers, Inc.Method and apparatus to automatically optimize the pacing mode and pacing cycle parameters of a dual chamber pacemakerUS5545186Mar 30, 1995Aug 13, 1996Medtronic, Inc.Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmiasUS5545202Aug 4, 1994Aug 13, 1996Cardiac Pacemakers, Inc.Body implantable defibrillation systemUS5549655Sep 21, 1994Aug 27, 1996Medtronic, Inc.Method and apparatus for synchronized treatment of obstructive sleep apneaUS5590648Apr 7, 1994Jan 7, 1997Tremont MedicalPersonal health care systemUS5593431Mar 30, 1995Jan 14, 1997Medtronic, Inc.Medical service employing multiple DC accelerometers for patient activity and posture sensing and methodUS5603732Nov 6, 1995Feb 18, 1997Cardiac Pacemakers, Inc.Subcutaneous defibrillation electrodesUS5605151Feb 21, 1995Feb 25, 1997Lynn; Lawrence A.Method for the diagnosis of sleep apneaUS5632281Feb 6, 1995May 27, 1997Rayburn; Daniel B.Non-invasive estimation of arterial blood gasesUS5645570Jun 17, 1994Jul 8, 1997Sorin Biomedica S.P.A.Method and device for monitoring and detecting sympatho-vagal activity and for providing therapy in response theretoUS5693000Jun 6, 1996Dec 2, 1997Pacesetter, Inc.Cardiomyoplasty simulator with feedback controlUS5697951Apr 25, 1996Dec 16, 1997Medtronic, Inc.Implantable stimulation and drug infusion techniquesUS5701894Nov 9, 1995Dec 30, 1997Del Mar AvionicsModular physiological computer-recorderUS5704345Nov 4, 1994Jan 6, 1998Resmed LimitedDetection of apnea and obstruction of the airway in the respiratory systemUS5713933Nov 30, 1994Feb 3, 1998Medtronic, Inc.Method and apparatus for automatic pacing threshold determinationUS5715812Mar 12, 1996Feb 10, 1998Nellcor Puritan BennettCompliance meter for respiratory therapyUS5720771Aug 2, 1995Feb 24, 1998Pacesetter, Inc.Method and apparatus for monitoring physiological data from an implantable medical deviceUS5738102Jul 31, 1996Apr 14, 1998Lemelson; Jerome H.Patient monitoring systemUS5792188Jan 23, 1997Aug 11, 1998Pacesetter, Inc.Capacitor reformation and measurement in an implantable cardioverter/defibrillator (ICD)US5794615Jul 15, 1996Aug 18, 1998Respironics, Inc.Method and apparatus for providing proportional positive airway pressure to treat congestive heart failureUS5800470Mar 11, 1996Sep 1, 1998Medtronic, Inc.Respiratory muscle electromyographic rate responsive pacemakerUS5802188Jul 24, 1997Sep 1, 1998Hewlett-Packard CompanyIntegrated chassis and resonance component in an electronic deviceUS5814087Dec 18, 1996Sep 29, 1998Medtronic, Inc.Rate responsive pacemaker adapted to adjust lower rate limit according to monitored patient blood temperatureUS5826579Oct 25, 1996Oct 27, 1998University Technologies International, Inc.Remote-controlled mandibular positioning device and method of using the deviceUS5836987Mar 12, 1997Nov 17, 1998Cardiac Pacemakers, Inc.Apparatus and method for optimizing cardiac performance by determining the optimal timing interval from an accelerometer signalUS5839430Jan 13, 1997Nov 24, 1998Cama; JosephCombination inhaler and peak flow rate meterUS5844680Sep 24, 1995Dec 1, 1998Byk-Gardner GmbhDevice and process for measuring and analysing spectral radiation, in particular for measuring and analysing color characteristicsUS5855593Jun 12, 1997Jan 5, 1999Medtronic, Inc.Prioritized rule based method and apparatus for diagnosis and treatment for arrhythmiasUS5861011Feb 14, 1997Jan 19, 1999Vitatron Medical, B.V.For generating pace pulses for delivery to a patientUS5891023Jan 27, 1997Apr 6, 1999Lynn; Lawrence A.Apparatus for the diagnosis of sleep apneaUS5902250Mar 31, 1997May 11, 1999President And Fellows Of Harvard CollegeHome-based system and method for monitoring sleep state and assessing cardiorespiratory riskUS5911218Mar 18, 1997Jun 15, 1999Dimarco; Anthony FortunatoMethod and apparatus for electrical stimulation of the respiratory muscles to achieve artificial ventilation in a patientUS5916243Mar 1, 1996Jun 29, 1999Cardiac Pacemakers, Inc.Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillationUS20020103442 *Nov 30, 2001Aug 1, 2002Mulligan Lawrence J.Method and apparatus for measurement of mean pulmonary artery pressure from a ventricle in an ambulatory monitorUS20040138719 *Apr 21, 2003Jul 15, 2004Cho Yong K.System and method for automatically monitoring and delivering therapy for sleep-related disordered breathingUS20070083241 *Dec 6, 2006Apr 12, 2007Bardy Gust HSystem and method for generating baseline data for automated management of edemaUS20070149860 *Jun 19, 2006Jun 28, 2007Lynn Lawrence AMicroprocessor system for the analysis of physiologic and financial datasets* Cited by examinerNon-Patent CitationsReference1Ajilore et al., Nightcap: Laboratory and home-based evaluation of a portable sleep monitor, 32 Psychophysiology, 32-98, 1995. Abstract only.2Altshule et al., The Effect of Position on Periodic Breathing in Chronic Cardiac Decomposition, New Eng. Journal of Med., vol. 259, No. 22, pp. 1064-1066, Nov. 27, 1958.3Balaban et al., Feasibility of Screening for Sleep Apnea Using Pacemaker Impedance Sensor, NASPE, 2001.4Bradley et al, Cardiac Output Response to Continuous Positive Airway Pressure In Congestive Heart Failure, 145 Am. Rev. Respir. Dis. 377-382, 1992. Abstract only.5Bradley et al., Pathophysiologic and Therapeutic Implications of Sleep Apnea in Congestive Heart Failure, 3 J. Cardiac Failure 223-240, 1996. Abstract only.6Bradley et al., Sleep Apnea and Heart Failure, Part I: Obstructive Sleep Apnea, 107 Circulation 1671-1678, 2003.7Buda et al., Effect Of Intrathoracic Pressure On Left Ventricular Performance, 301 Engl. J. Med. 453-459, 1979. Abstract only.8Calvin et al., Positive End-Expiratory Pressure (PEEP) Does Not Depress Left Ventricular Function in Patients With Pulmonary Edema, 124 Am. Rev. Respir. Dis. 121-128 (1981). (Abstract only) Junyu et al., Posture Detection Algorithm Using Multi Axis DC-Accelerometer, Pace vol. 22. Apr. 1999. Abstract only.9Dark et al., Breathing Pattern Abnormalities and Arterial Oxygen Desaturation During Sleep in the Congestive Heart Failure Syndrome, Chest, 6:833-6, Jun. 1987.10De Hoyos et al., Haemodynamic Effects of Continuous Positive Airway Pressure in Humans With Normal and Impaired Left Ventricular Function, 88 Clin. Sci. (Lond). 173-8, 1995. Abstract only.11Examiner Interview Summary dated Apr. 17, 2009 from U.S. Appl. No. 10/930,346, 2 pages.12Examiner Interview Summary dated Oct. 14, 2008 from U.S. Appl. No. 10/930,508, 4 pages.13Garrigue et al., Benefit of Atrial Pacing in Sleep Apnea Syndrome, 346 N. Engl. J. Med. 404-412, 2002. Abstract only.14Garrigue et al., Night Atrial Overdrive with DDD Pacing Results in a Significant Reduction of Sleep Apnea Episodes and QOL Improvement in Heart Failure Patients, NASPE, 2001.15Garrigue et al., Night Atrial Overdrive with DDD Pacing: A New Therapy for Sleep Apnea Syndrome, NASPE 21st Annual Scientific Sessions, Apr. 2000, vol. 23, No. 4, Part II, #591, 1 page, Abstract Only.16Giardino et al., Respiratory Sinus Arrhythmia is Associated with the Efficiency of Pulmonary Gas Exchange in Healthy Humans, 284 Am. J. Physiol. H1585-1591, 2003.17Hanson et al., Cardiac Gated Ventilation, 2433 SPIE 303-308, 1995.18Hilton et al., Evaluation of Frequency and Time-frequency Spectral Analysis of Heart Rate Variability as a Diagnostic Marker of the Sleep Apnea Syndrome, 37 Med. Biol. Eng. Comput. 760-769, 1999.19Hoffman et al., Cheyne-Stokes Respiration in Patients Recovering from Acute Cardiogenic Pulmonary Edema, Chest, 97:410-12, 1990.20International Search Report and Written Opinion from European Application No. 08075738.8 dated Jul. 26, 2010, 4 pages.21International Search Report dated Dec. 22, 2004 from PCT Application No. PCT/US2004/030787, 8 pages.22Javaheri et al., Sleep Apnea in 81 Ambulatory Male Patients with Stable Heart Failure: Types and Their Prevalences, Consequences, and Presentations, 97 Circulation 2154-2159, 1998.23Kaye et al., Acute Effects of Continuous Positive Airway Pressure on Cardiac Sympathetic Tone in Congestive Heart Failure, 103 Circulation 2336-2338, 2001.24Laude et al., Effects of Breathing Pattern on Blood Pressure and Heart Rate Oscillations in Humans, 20 Clin. Exp. Pharmol. Phisiol 619, 625, 1993. Abstract only.25Lenique et al., Ventilatory and Hemodynamic Effects of Continuous Positive Airway Pressure in Left Heart Failure, 155 Am. J. Respir. Crit. Care Med. 500-505, 1997. Abstract only.26Mansfield, D. et al., Effects of Continuous Positive Airway Pressure on Lung Function in Patients with Chronic Obstructive Pulmonary Disease and Sleep Disordered Breathing, Respirology 365-70 (1999). Abstract only.27Mehta et al., Effects of Continuous Positive Airway Pressure on Cardiac Volumes In Patients With Ischemic and Dilated Cardiomyopathy, 161 Am. J. Respir. Crit. Care Med. 128-134, 2000.28Naughton et al., Effects of Continuous Positive Airway Pressure on Intrathoracic and Left Ventricular Transmural Pressure in Congestive Heart Failure, 91 Circulation 1725-1731, 1995.29Notice of Allowance dated Feb. 24, 2009 from U.S. Appl. No. 10/930,508, 8 pages.30Notice of Allowance dated Feb. 24, 2009 from U.S. Appl. No. 10/943,508, 21 pages.31Notice of Allowance dated Sep. 21, 2009 from U.S. Appl. No. 10/930,346, 8 pages.32Office Action dated Apr. 1, 2010 from U.S. Appl. No. 10/943,077, 3 pages.33Office Action dated Dec. 21, 2008 from European Application No. 04784602.7, 6 pages.34Office Action dated Jan. 10, 2008 from European Application No. 04784602.7, 3 pages.35Office Action dated May 9, 2007 from European Application No. 04784602.7, 3 pages.36Office Action from patent U.S. Appl. No. 10/930,508 dated Jul. 9, 2008, 14 pages.37Office Action from U.S Appl. No. 10/943,077 dated Jul. 7, 2009, 16 pages.38Office Action from U.S. Appl. No. 10/930,508 dated Feb. 14, 2008, 13 pages.39Office Action from U.S. Appl. No. 10/930,508 dated Jun. 25, 2007, 15 pages.40Office Action from U.S. Appl. No. 10/943,077 dated Jan. 21, 2010, 15 pages.41Office Action from U.S. Appl. No. 10/943,077 dated Nov. 26, 2008, 21 pages.42Office Action Response dated Apr. 17, 2008 from European Application No. 04784602.7, 10 pages.43Office Action Response dated Aug. 24, 2009 from U.S. Appl. No. 10/930,346, 10 pages.44Office Action Response dated May 7, 2009 from U.S. Appl. No. 10/930,346, 9 pages.45Office Action Response submitted Apr. 14, 2008 to office action dated Feb. 14, 2008 from U.S. Appl. No. 10/930,508, 12 pages.46Office Action Response submitted Mar. 11, 2010 to office action dated Jan. 21, 2010 from U.S. Appl. No. 10/943,077, 12 pages.47Office Action Response submitted Mar. 19, 2009 to office action dated Nov. 26, 2008 from U.S. Appl. No. 10/943,077, 11 pages.48Office Action Response submitted Nov. 21, 2007 to office action dated Jun. 25, 2007 from U.S. Appl. No. 10/930,508, 12 pages.49Office Action Response submitted Nov. 6, 2008 to office action dated Jul. 9, 2008 from U.S. Appl. No. 10/930,508, 9 pages.50Office Action Response submitted Oct. 7, 2009 to office action dated Jul. 7, 2009 from U.S. Appl. No. 10/943,077, 11 pages.51Pinsky et al., Hemodynamic Effect of Cardiac Cycle-Specific Increases in Intrathoracic Pressure, 6 J. Appl. Physiol. 604-612, 1986.52Potkin et al., Effect of positive end-expiratory pressure on right and left ventricular function in patients with the adult respiratory distress syndrome, 135 Am. Rev. Respir. Dis. 307-311, 1987. Abstract only.53Reddel et al., Analysis of Adherence to Peak Flow Monitoring When Recording of Data is Electronic, BMJ 146-147 (2002).54Rees et al., Paroxysmal Nocturnal Dyspnoea and Periodic Respiration, The Lancet, Dec. 22-29, pp. 1315-1317, 1979. Abstract only.55Roche et al., Screening of Obstructive Sleep Apnea Syndrome by Heart Rate Variability Analysis, 100 Circulation 1411-1455, 1999.56Scharf, Effects of Continuous Positive Airway Pressure on Cardiac Output in Experimental Heart Failure, 19 Sleep S240-2, 1996. Abstract only.57Steltner et al., Diagnosis of Sleep Apnea by Automatic Analysis of Nasal Pressure and Forced Oscillation Impedance. Am. Journal Respiratory Critical Care Medicine, vol. 165, pp. 940-944, 2002.58Tkacova et al., Left Ventricular Volume in Patients with Heart Failure and Cheyne-Strokes Respiration during Sleep, Am. Journal, Respir. Crit. Care Med., vol. 156, pp. 1549-1555, 1997.59U.S. Office Action dated Aug. 3, 2009 for U.S. Appl. No. 10/930,346, 19 pages.60U.S. Office Action dated Dec. 10, 2008 for U.S. Appl. No. 10/930,346, 13 pages.61Vanninen et al., Cardiac Sympathovagal Balance During Sleep Apnea Episodes, 16 Clin. Physiol. 209-216, 1996. Abstract only.62Verrier et al., Sleep Related Cardiovascular Risk: New Home-Based Monitoring Technology for Improved Diagnosis and Therapy, 2 A.N.E. 158-175, 1997.63Verrier et al., Sleep, dreams, and sudden death: the case for sleep as an autonomic stress test for the heart, 31 Cardiovascular Research 181-211, 1996.64Waldemark et al., Detection of Apnea using Short Window FFT Technique and Artificial Neural Network, 3390 SPIE International Society for Optical Engineering 122-133, 1998.65Weber et al. Effect of CPAP and BIPAP on stroke volume in patients with obstructive sleep apnea syndrome. Pneumolgie; 49(3):233-5, 1995. Abstract only.66Young et al., The Occurrence of Sleep-Disordered Breathing Among Middle Aged Adults, N. Engl. J. Med. 1230-1235, 1993. Abstract only.Classifications U.S. Classification600/529International ClassificationA61B5/091, A61B5/083, A61B5/0205, A61N1/365, A61N1/08, A61N1/368, A61N1/36, A61M16/00, A61M11/00, A61B5/08, A61B5/087Cooperative ClassificationA61B5/7275, A61B5/091, A61B5/4818, A61M2016/0021, A61N1/36521, A61M2205/3569, A61B5/0809, A61B5/0205, A61B5/083, A61M16/0051, A61N1/365, A61M2016/0036, A61N1/3601, A61M11/00, A61M2205/3523, A61N1/3684, A61B5/087European ClassificationA61M16/00K, A61B5/08J, A61B5/48C8, A61N1/365, A61N1/36C, A61B5/0205RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google