Source: https://patents.google.com/patent/CN103237515B/en
Timestamp: 2019-11-13 23:53:00
Document Index: 78074235

Matched Legal Cases: ['Application no 2011', 'Application no. 13', 'art. 12', 'ART0', 'ART0', 'ART03', 'ART03']

CN103237515B - Flushing fluid dispensing system for a flexible electrode, - Google Patents
Flushing fluid dispensing system for a flexible electrode, Download PDF
CN103237515B
CN103237515B CN201280003945.8A CN201280003945A CN103237515B CN 103237515 B CN103237515 B CN 103237515B CN 201280003945 A CN201280003945 A CN 201280003945A CN 103237515 B CN103237515 B CN 103237515B
CN201280003945.8A
CN103237515A (en
S·C·克里斯蒂安
2011-06-16 Priority to US13/162,417 priority Critical patent/US8979840B2/en
2011-06-16 Priority to US13/1624,17 priority
2012-02-27 Application filed by 圣犹达医疗用品电生理部门有限公司 filed Critical 圣犹达医疗用品电生理部门有限公司
2013-08-07 Publication of CN103237515A publication Critical patent/CN103237515A/en
2016-11-02 Publication of CN103237515B publication Critical patent/CN103237515B/en
具有纵向轴(64)的消融电极组件(10)包括电极芯构件(44)、电极外壳(46)、以及冲洗液分配元件(100)。 Having a longitudinal axis (64) of the ablation electrode assembly (10) comprises (44), the electrode housing (46), and a rinsing fluid distribution element (100) of the electrode core member. 电极芯构件(44)包括绝热体，其具有第一端(48)、第二端(50)、以及至少一个冲洗通道。 (44) comprises an electrode core insulation member, having a first end (48), a second end (50), and at least one irrigation channel. 电极外壳(46)包括导电材料，限定内部容积并具有第一端(48)和第二端(50)。 An electrode housing (46) comprises an electrically conductive material defining an interior volume and having a first end (48) and a second end (50). 电极外壳(46)的第二端(50)被配置为连接至电极芯构件(44)的第一端(48)。 A second end (50) housing an electrode (46) is arranged to a first end (48) connected to an electrode core member (44). 电极外壳(46)足够柔韧以相对于消融电极组件(10)的纵向轴(64)偏转电极外壳(46)的远端(78)。 An electrode housing (46) sufficiently flexible with respect to the longitudinal axis (64) ablation electrode assembly (10) housing the distal end of the deflection electrodes (46) (78). 冲洗液分配组件包括第一端和第二端，其中冲洗液分配元件(100)的第二端在冲洗液分配元件(100)和电极芯构件(44)之间限定环形冲洗端口(106)。 Flushing fluid dispensing assembly includes a first and second ends defining an annular irrigation port (106) between (44) wherein the irrigation fluid dispensing member (100) at a second end of the rinsing liquid dispensing element (100) and an electrode core member.
用于柔性电极的冲洗液分配系统 Flushing fluid dispensing system for a flexible electrode,
[0002] 本申请要求享有2011年6月16日提交的美国专利申请no. 13/162,417('417申请） 的优先权，其是2011年6月2日提交的且当前未决的美国专利申请no. 13/151，750('750申请）的部分连续申请案，' 750申请是2010年12月28日提交的且当前未决的美国专利申请no. 12/979,803('803申请）的部分连续申请案；以及该申请是2010年12月17日提交的美国专利申请no .12/971,645('645申请）的部分连续申请案。 [0002] This application claims the benefit of U.S. Patent Application no 2011 years. 6 is filed May 16. 13 / 162,417 ( '417 Application) filed, which is June 2, 2011 and filed currently pending U.S. Patent Application no. 13 / 151,750 ( '750 application part) continuous application,' 750 application is December 28, 2010 and filed currently pending U.S. Patent application no part. 12 / 979,803 ( '803 application) of continuous application; and the US patent application is December 17, 2010 filed no .12 / 971,645 ( '645 application) is part of the continuous application. '417申请、'750申请、'803申请、 '645申请的全部内容通过引用包含于此，如同在本文中将其完全阐述一样。 The entire contents of '417 application, the' 750 application, the '803 application, the' 645 application is incorporated by reference as if fully set forth herein in the same.
[0004] a.技术领域 [0004] a. Field
[0005] 本发明总体上涉及一种消融电极组件，其包括柔性电极外壳和冲洗液分配元件。 [0005] The present invention generally relates to An ablation electrode assembly, comprising a flexible housing and an electrode rinse solution dispensing member.
[0007] 电生理导管用于各种诊断和/或治疗的医疗程序以诊断和/或矫正诸如房性心律失常的疾病，例如包括异位房性心动过速、心房颤动、以及心房扑动。 [0007] Electrophysiology catheters are used in various diagnostic and / or therapeutic medical procedures to diagnose and / or correction of diseases such as atrial arrhythmia, including for example, ectopic atrial tachycardia, atrial fibrillation, and atrial flutter. 房性心律失常可以产生多种危险情形，包括心率不规则、同步房室收缩的缺失、以及心室的血流郁滞，这可能导致各种有症状和无症状疾病甚至死亡。 Atrial arrhythmias can produce a variety of dangerous situations, including irregular heart rate, loss of synchronous atrioventricular contractions, and ventricular blood flow stagnation, which may lead to a variety of symptomatic and asymptomatic disease and even death.
[0008] 使用电生理导管的医疗程序包括穿过患者脉管至患者心脏或心室或静脉布置的第一诊断导管。 [0008] Using an electrophysiologic catheter through the patient's vasculature comprising a medical procedure to a patient's heart or ventricular vein or arranged a first diagnostic catheter. 携带一个或多个电极的电生理导管可以用于心脏标测或诊断、消融和/或其他治疗输送模式、或用于这两者。 Carries one or more electrodes may be used for electrophysiological cardiac mapping catheter or diagnosis, ablation, and / or other therapy delivery mode, or to both. 一旦在目的部位，治疗可以例如包括射频(RE)消融、冷冻消融、激光消融、化学消融、高强度聚焦超声消融、微波消融。 Once the target site, for example, treatment may include radio frequency (RE) ablation, cryoablation, laser ablation, chemical ablation, high intensity focused ultrasound ablation, microwave ablation. 电生理导管将消融能量施加至心肌组织以产生心肌组织中的一个或多个损伤，以及经常产生连续的或线性的及透壁的损伤。 Electrophysiology catheter ablation energy to the cardiac tissue to create a more or myocardial tissue damage, and often damaged or linear and continuous transmural. 该损伤破坏了不期望的心脏活动路径并由此限制、捕获、或阻止可以形成心律不齐基础的错误传导信号。 The damage does not destroy the desired path and thereby limit cardiac activity, capture, or prevent the error signal transduction may form the basis of an arrhythmia.
[0009] 在RF消融中，局部温度提高可以导致消融电极上的凝块形成，其导致阻抗增大。 [0009] In RF ablation, the local temperature increase can result in clot formation on the ablation electrode, which results in increase in impedance. 随着阻抗增大，更多能量穿过电极的没有凝结的部分，产生甚至更高的局部温度并进一步增加凝块形成和阻抗。 As the impedance increases, more energy is not condensed through the portion of the electrode, resulting in an even higher local temperatures and further increasing coagulum formation and the impedance. 最后，足够多的血凝块凝结在电极上，从而没有能量进入靶组织，进而需要将导管从脉管系统移除、清洁电极，以及将导管重新定位在心脏系统内的期望位置。 Finally, enough clot condensed on the electrode, so that no energy into the target tissue, and further requires removing the catheter from the vasculature, the cleaning electrode, and a desired position of the catheter repositioned within the heart of the system. 该过程不仅是耗时的，而且由于先前已经消融的靶组织中减小的电活动而难以返回至先前位置。 This process is not only time-consuming, and because the electrical activity of the target tissue ablation has been previously reduced in difficult return to the previous position. 近期研究已经证实了RF消融中所谓的软血栓的形成。 Recent studies have confirmed the formation of the so-called RF ablation of soft thrombus. 软血栓的形成由热诱导蛋白质变性和聚合产生，以及独立于血清中的肝素浓度发生。 Soft thrombus formation induced by thermal protein denaturation and aggregation produced, and is independent of the heparin concentration in the serum occurs. 另外，RF消融可以生成很多热量，其在不控制时会导致过多的组织破坏，诸如组织炭化和蒸汽爆开等。 Further, the RF ablation may generate a lot of heat, which, when not controlled can lead to excessive tissue destruction, such as tissue charring and steam burst like.
[0010]因此，期望的是监测和/或控制消融电极组件和/或靶组织的温度。 [0010] Accordingly, it is desirable to monitor and / or control the temperature of the ablation electrode assembly and / or the target tissue. 诸如热电偶和/ 或热敏电阻的热传感器可用于监测消融电极组件的温度。 Thermal sensors such as thermocouples and / or thermistors may be used to monitor the temperature of the ablation electrode assembly. RF消融导管可以配置为在RF消融期间经由热传感器提供温度反馈以调节RF消融周期的一个或多个参数。 RF ablation catheter may be configured to provide during RF ablation temperature feedback to adjust one or more parameters of the RF ablation cycle via a heat sensor. 因此，期望的是改善电极和组织接触面之间的温度关联以提供关于组织温度的更精确温度反馈，从而控制RF 消融周期期间的能量输送和/或其他参数。 Thus, it is desirable to improve the correlation between the temperature of the electrode and the tissue contacting surface in order to provide for a more accurate temperature of the tissue temperature feedback to control the RF ablation energy during transport periods and / or other parameters. 还期望的是使用消融电极组件来提供RF消融期间的冲洗液。 It is also desirable to provide the use of an ablation electrode assembly irrigation fluid during RF ablation. 另外，期望的是提供一种柔性电极，其可以在柔性电极与靶组织物理接触时通过偏转和/或经历变形而更好地配置以符合用于治疗的组织表面。 Further, it is desirable to provide a flexible electrode which can conform to a tissue surface deflection for the treatment and / or subjected to deformation better when the flexible electrode disposed in contact with tissue physical target. 这样，柔性电极可以更好地适应心脏解剖结构，以及电极与心脏解剖结构的一致可以确保更有效的能量输送。 Thus, the flexible electrodes can be better adapted to the anatomy of the heart, and consistent with the cardiac anatomy electrode ensures a more efficient energy delivery.
[0011] 期望的是在消融电极组件的电极和组织接触面之间具有改善的温度关联。 [0011] desirable to have an improved correlation between the temperature of the electrodes and the tissue contacting surface of the ablation electrode assembly. 在一些实施方式中，还期望的是包括一种通过诸如生理盐水的生物兼容液体冲洗消融电极组件和/或患者体内的靶区域的机构，从而减少炭化并抑制凝块和/或软血栓的形成，以及与传统的、非冲洗导管相比可以在相同的功率设置下进行更深和/或更大体积的损伤。 In some embodiments, it is desirable to further include one by a liquid, such as a biocompatible saline irrigated ablation electrode assembly and / or mechanism of the target region of the patient, thereby reducing charring and inhibits clot and / or soft thrombus formation , and compared with traditional, non-irrigation catheter may be deeper and / or larger volumes of injury at the same power setting. 这转而可以在RF消融期间允许更大的能量输送。 This in turn allows greater energy delivery during RF ablation. 生物兼容液体流（即，冲洗液)可以是湍流的从而提供邻近消融电极组件表面的包络流模式以用于混合、转移、和/或稀释与消融电极组件接触的血液，从而阻止停滞及凝块形成。 Biocompatible fluid flow (i.e., rinse liquid) may be to provide a turbulent flow pattern adjacent to the envelope surface of the ablation electrode assembly for mixing, transfer, and / or dilution with the ablation electrode assembly in contact with the blood, thereby preventing stagnation and coagulation block is formed. 另外，期望的是电极符合心脏解剖结构以改善RF消融期间的能量效率。 In addition, it is desirable that the electrode consistent with cardiac anatomy to improve energy efficiency during RF ablation.
[0012] 根据本发明实施方式的消融电极组件具有纵向轴、电极芯构件、电极外壳、以及冲洗液分配元件。 [0012] longitudinal axis of the electrode core member, an electrode housing, and the rinse liquid distribution element ablation electrode assembly according to an embodiment of the present invention has. 电极芯构件包括绝热体，其具有降低的热传导性。 Electrode core member comprises a heat insulating body, which has a reduced thermal conductivity. 电极芯构件具有第一端、 第二端、以及至少一个冲洗通道。 Electrode core member having a first end, a second end, and at least one irrigation channel. 根据本发明的实施方式，电极芯构件还包括外表面和限定空腔的内表面。 According to an embodiment of the present invention, the electrode core member further comprises an outer surface and an inner surface defining a cavity. 所述至少一个冲洗通道从内部空腔延伸至电极芯构件的外表面。 Said at least one channel extending from the outer surface of the electrode core member to the interior cavity of flushing. 根据本发明的实施方式，电极芯构件还包括轴向延伸通道，其从电极芯构件的内部空腔延伸至电极外壳的第一端。 According to an embodiment of the present invention, the electrode core member further comprises an axially extending passageway which extends from the interior cavity of the electrode core member to the first end of the electrode housing. 消融电极组件还可以包括至少一个端口，其从轴向延伸通道延伸至电极外壳的第一端，其中所述端口定向为相对于根据本发明实施方式的消融电极组件的纵向轴成锐角。 Ablation electrode assembly may further comprise at least one port extending from a first end of the axial passage extending to the electrode of the housing, wherein said port is oriented at an acute angle relative to the longitudinal axis of the ablation electrode assembly according to an embodiment of the present invention. 轴向延伸通道的外围的至少一部分和长度的至少一部分可以包括非导电材料的涂层。 Peripheral channel extending axially at least a portion of at least a portion of the length of the coating may comprise non-conductive material.
[0013] 电极外壳包括导电材料。 [0013] The housing comprises a conductive electrode material. 电极外壳限定内部容积并具有第一端和第二端。 A housing defining an interior volume and an electrode having a first end and a second end. 电极外壳的第二端被配置为连接至电极芯构件的第一端。 The second end of the electrode housing is configured to be connected to a first end of the electrode core member. 电极外壳足够柔韧以相对于消融电极组件的纵向轴偏转电极外壳的远端。 Sufficiently flexible electrode housing relative to the longitudinal axis of the distal end of the ablation electrode case deflection electrode assembly. 冲洗液分配元件具有第一端和第二端。 A first member having a dispensing flushing fluid end and a second end. 冲洗液分配元件的第二端在冲洗液分配元件和电极芯构件之间限定环形冲洗端口。 Rinse liquid distribution element between the second end of the rinse liquid distribution element and the electrode core member defining an annular flush port. 根据本发明的第一实施方式，电极外壳的至少一部分包括第一组凸起，其至少部分限定对应的第一组凹槽，以及电极外壳的至少一部分包括第二组凸起，其至少部分限定对应的第二组凹槽。 According to a first embodiment of the present invention, at least a part of the electrode housing comprises a first set of protrusions, which at least partially defines a first set of grooves corresponding to at least a portion of the housing and an electrode comprises a second set of projections, at least partially defining corresponding to a second set of grooves. 第一组凸起的至少一个被配置为与第二组凹槽中的至少一个互锁，以及第二组凸起的至少一个被配置为与第一组凹槽中的至少一个互锁。 A first set of at least one projection is configured as a second set of grooves and the at least one interlock, and a second set of at least one projection is configured to at least one interlock groove and the first group. 在本发明的实施方式中，第一组凸起中的每一个与第二组凸起中的每一个可以是梯形形状。 In an embodiment of the present invention, a first group of projections with one each of each of the second set of protrusions may be a trapezoidal shape. 在本发明的实施方式中，第一组凸起中的每一个与第二组凸起中的每一个可以是圆形形状。 In an embodiment of the present invention, a first group of projections with one each of each of the second set of protrusions may be circular in shape.
[0014] 根据本发明的第二实施方式，电极外壳可以包括缠绕或编织的金属线。 [0014] According to a second embodiment of the present invention, the electrode housing may comprise twisted or braided metal wire. 根据本发明的第三实施方式，电极外壳可以包括聚合物(例如且不限于硅酮），所述聚合物具有以预定密度分布于其中的导电颗粒以实现期望的导电性。 According to a third embodiment of the present invention, the electrode housing may comprise a polymer (e.g. silicone and without limitation), the conductive polymer having a predetermined density distribution of the conductive particles therein to achieve the desired. 根据本发明的各种实施方式，这些颗粒可以包括金、银、铂、铱、钛、钨、或其组合。 According to various embodiments of the present invention, these particles may include gold, silver, platinum, iridium, titanium, tungsten, or combinations thereof.
[0015] 根据本发明的实施方式，消融电极组件还可以包括堵塞物(plug)，其布置在由电极外壳限定的内部容积中。 [0015] According to an embodiment of the present invention, the ablation assembly may also include an electrode plug (Plug), which is disposed in the interior volume defined by the electrode housing. 该堵塞物可以包括聚合物(例如且不限于硅酮材料）。 The plug may comprise a polymer (e.g. and without limitation, silicone material). 根据本发明的实施方式，该堵塞物可以具有预定的硬度以实现期望的柔性。 According to an embodiment of the present invention, the plug may have a flexibility to achieve a predetermined desired hardness.
[0016] 所述冲洗液分配元件可以包括孔环并且还可以包括液体成形构件，诸如通道、膛线、凸台、隆起、斜面、或其组合，从而改善冲洗液的液体流动特征。 [0016] The rinsing liquid distribution element may comprise eyelets and may further include forming a liquid component, such as a channel, rifling, boss, bulge, ramp, or combinations thereof, to improve the flow characteristics of the liquid rinse solution.
[0017] 根据本发明实施方式的用于心脏组织的心脏消融的系统包括导管、布置在导管内的至少一个热传感器、消融发生器、以及电子控制单元(E⑶）。 [0017] The catheter comprises at least one thermal sensor disposed within the catheter for heart cardiac tissue according to embodiments of the present invention an ablation system, an ablation generator, and an electronic control unit (E⑶). 该导管包括具有液体管腔的导管轴杆、以及连接至导管轴杆的电极组件。 The catheter includes a catheter shaft having a fluid lumen, and an electrode assembly connected to the catheter shaft. 该电极组件包括电极芯构件、电极外壳、以及冲洗液分配元件。 The electrode assembly comprises an electrode core member, an electrode housing, and the rinse liquid distribution element. 电极芯构件包括绝热体，其具有降低的热传导性。 Electrode core member comprises a heat insulating body, which has a reduced thermal conductivity. 电极芯构件具有第一端、第二端、以及至少一个冲洗通道。 Electrode core member having a first end, a second end, and at least one irrigation channel. 电极外壳包括导电材料。 The housing comprises a conductive electrode material. 电极外壳限定内部容积并具有第一端和第二端。 A housing defining an interior volume and an electrode having a first end and a second end. 电极外壳的第二端被配置为连接至电极芯构件的第一端。 The second end of the electrode housing is configured to be connected to a first end of the electrode core member. 电极外壳足够柔韧以相对于消融电极组件的纵向轴偏转电极外壳的远端。 Sufficiently flexible electrode housing relative to the longitudinal axis of the distal end of the ablation electrode case deflection electrode assembly. 冲洗液分配元件具有第一端和第二端，其中冲洗液分配元件的第二端在冲洗液分配元件和电极芯构件之间限定环形冲洗端口。 A first member having a dispensing flushing fluid end and a second end, wherein the rinse liquid distribution element between the second end of the rinse liquid distribution element and the electrode core member defining an annular flush port. 消融发生器可以电连接到电极组件的至少一部分，以及ECU可以可操作地连接至至少一个热传感器。 Ablation generator may be electrically connected to at least a portion of the electrode assembly, and the at least one thermal sensor may be operatively connected to the ECU. ECU可以被配置为从所述多个热传感器中的至少一个接收输入数据，并可以被配置为至少部分地基于所述输入数据控制至电极组件的能量输送和冲洗液输送。 ECU may be configured to receive input data from at least one of said plurality of thermal sensors, and may be configured as a wash fluid delivery and conveyed at least in part on the control data input energy to the electrode assembly.
[0018] 图1是用于执行与心脏组织相关的多个诊断和/或治疗功能的系统的示意图。 [0018] FIG. 1 is a schematic view of the implementation of the system associated with the cardiac tissue more diagnostic and / or therapeutic functions used.
[0019] 图2是根据本发明第一实施方式的消融电极组件的等距局部透明视图。 [0019] FIG. 2 is an isometric view of a partially transparent ablation electrode assembly according to a first embodiment of the present invention.
[0020] 图3是图2的消融电极组件的剖面图。 [0020] FIG. 3 is a sectional view of the electrode ablation assembly of FIG.
[0021] 图4是图2的消融电极组件的等距局部透视图，其示出了图2的消融电极组件的外部壳体的柔性。 [0021] FIG. 4 is a partial isometric perspective view of the electrode ablation assembly of FIG. 2, which shows a flexible outer housing ablation electrode assembly 2 of FIG.
[0022] 图5A是根据本发明第一实施方式的图2的消融电极组件的外部壳体的一部分的等距视图。 [0022] FIG 5A is an isometric view of a portion of an ablation electrode according to the outer housing assembly showing the first embodiment of the present invention is 2.
[0023] 图5B是根据本发明第二实施方式的图2的消融电极组件的外部壳体的一部分的等距视图。 [0023] FIG 5B is an isometric view of a portion of an ablation electrode according to an external housing assembly showing a second embodiment of the present invention is 2.
[0024]图6是根据本发明第二实施方式的消融电极组件的等距局部透视图。 [0024] FIG. 6 is a partial isometric perspective view of the ablation electrode assembly according to a second embodiment of the present invention.
[0025]图7是图6的消融电极组件的剖面图。 [0025] FIG. 7 is a sectional view of the electrode ablation assembly of FIG.
[0026]图8是根据本发明第三实施方式的消融电极组件的等距局部透视图。 [0026] FIG. 8 is a partial isometric perspective view of the ablation electrode assembly according to a third embodiment of the present invention.
[0027] 图9是根据本发明第四实施方式的消融电极组件的等距局部透视图。 [0027] FIG. 9 is a partial isometric perspective view of the ablation electrode assembly according to a fourth embodiment of the present invention.
[0028] 本发明通常涉及一种冲洗消融电极组件。 [0028] The present invention generally relates to an irrigated ablation electrode assembly. 出于描述目的，本文所述各实施方式中的类似方面将通过相似参考数字来指代。 For purposes of description, similar aspects of the embodiments described herein will be referred to by like reference numerals. 然而，可以意识到的是，各方面的结构在不同实施方式中可以不同。 However, it will be appreciated that the configuration of each aspect may vary in different embodiments.
[0029]参照图1，消融电极组件10可以包括冲洗导管系统12的部件，用于体内组织(例如， 靶组织区域14)的检查、诊断、和/或治疗。 [0029] Referring to FIG 1, the electrode assembly 10 may include an ablation catheter system flushing member 12 for body tissue (e.g., the target tissue region 14) of the examination, diagnosis and / or treatment. 在示例性实施方式中，冲洗导管组件可以包括消融导管16(例如，射频(RF)、冷冻消融、超声等）。 In an exemplary embodiment, the irrigation catheter assembly 16 may include an ablation catheter (e.g., a radio frequency (RF), cryoablation, ultrasound, etc.). 本发明通常指代RF消融电极和电极组件，但可以预料到的是，本发明同样可以应用于多种其他消融电极和电极组件，其中装置和靶组织区域的温度是诊断和/或治疗医疗程序期间的因素。 The present invention generally refers to the ablation electrode and the RF electrode assembly, but it is contemplated that the present invention is equally applicable to a variety of other ablation electrode and the electrode assembly, wherein the temperature of the device and the target tissue region is diagnostic and / or therapeutic medical procedures factors period.
[0030]仍参照图1，冲洗导管组件包括导管轴杆18,其是被配置为在体内移动的细长的、 管状的、柔性的构件。 [0030] Still referring to FIG. 1, irrigation catheter assembly comprises a flexible catheter shaft member 18, which is configured to move the body in an elongated, tubular. 导管轴杆18可以通过常规导引器引入血管或身体20内的其他结构中。 The catheter shaft 18 may be introduced into a blood vessel or other structures within the body 20 by conventional introducer. 可以通过牵引线、拉伸元件、所谓的推进元件或本领域公知的其他手段来操纵或引导导管轴杆18穿过身体至诸如靶组织区域14的期望位置。 By pull wire, a tensile member, other means of propulsion elements or so-called well-known in the art to manipulate the catheter or the guide shaft 18 passes through the body to a desired location such as the target tissue region 14.
[0031]冲洗导管组件还包括至少一个液体管腔或液体输送管22,其布置在导管轴杆18 内，最佳示于图2。 [0031] irrigation catheter assembly further comprises at least one liquid or a liquid delivery tube lumen 22, disposed within the catheter shaft 18, best shown in FIG. 液体输送管22被配置为将液体供给至消融电极组件10。 A liquid delivery tube 22 is configured to supply liquid to the ablation electrode assembly 10. 现在参照图1-2， 冲洗导管组件的液体输送管22可以连接至液体源24,其通过栗26提供诸如生理盐水或药物的生物相容液体，所述栗26可以例如包括固定速率滚子栗或可变容积注射栗，其具有来自液体源的重力馈给以用于冲洗。 Referring now to FIGS. 1-2, irrigation catheter assembly of the liquid delivery tube 22 may be connected to a liquid source 24, such as that provided by the drug or saline Li biocompatible liquid 26, for example, the Li 26 may comprise a fixed rate roller Li variable volume injection or Li, with a gravity feed from a given liquid source for flushing. 液体源24和/或栗26在本领域中是常规的。 Fluid source 24 and / or Li 26 are conventional in the art. 在实施方式中， 液体源24和/或栗26可以包括从St.Jude Medical公司可获得的商品名为Cool Point™的商业可得装置。 In embodiments, the liquid source 24 and / or 26 may include commercial Li called Cool Point ™ available from St. Jude Medical Company of goods available means.
[0032]现参照图1，冲洗导管组件还可以包括一个或多个定位电极28,其安装在导管轴杆18中或导管轴杆18上。 [0032] Referring now to Figure 1, an irrigation catheter assembly may also include one or more positioning electrodes 28, mounted on the catheter shaft 18 or the catheter shaft 18. 电极28可以例如包括环形电极。 Electrode 28 may for example comprise a ring electrode. 电极28可以例如与可视化、导航和标测系统30-起使用。 Electrode 28 may be, for example, and visualization, navigation and mapping system from 30- use. 电极28可以被配置为提供指示导管轴杆18的至少一部分的位置及方向的信号。 Electrode 28 may be configured to provide a signal indicative of the position and orientation of at least a portion of the catheter shaft 18. 与电极28-起使用的可视化、导航和/或标测系统30可以包括基于电场的系统(或有时称为基于阻抗的系统），诸如具有型号名ENSITE NAVX(aka EnSite Classic以及EnSite系统的最新版本，表示为ENSITE VELOCITY)并从St.Jude Medical公司商业可得的， 以及如参照名称为"Method and Apparatus for Catheter Navigation and Location and Mapping in the Heart"的美国专利No .7,263,397所大致示出的，其全部内容通过引用包含于此。 Since the electrode 28- visualization, navigation and / or mapping system 30 may include a system using an electric field based on the latest version (or sometimes referred to as impedance-based systems), such as a model name ENSITE NAVX (aka EnSite Classic System and EnSite , expressed as ENSITE VELOCITY) and commercially available from St. Jude Medical company, and as described with reference entitled "Method and Apparatus for Catheter Navigation and Location and Mapping in the Heart" U.S. Patent No .7,263,397 substantially as shown, the entire contents of which are incorporated herein by reference. 可视化、导航和/或标测系统30可以包括电子控制单元(E⑶)和显示装置。 Visualization, navigation and / or mapping system 30 may include an electronic control unit (E⑶) and a display device. EOT 可以包括可编程微处理器或微控制器，但是可以可替换地包括专用集成电路(ASIChE⑶可以包括中央处理单元(CPU)和输入/输出（1/0)接口，E⑶可以通过该接口接收输入数据并且可以生成输出数据。E⑶还可以具有存储器，通过E⑶获取和生成的输入数据和/或输出数据可以被存储在ECU的存储器中。 EOT may comprise a programmable microprocessor or microcontroller, but may alternatively comprise application specific integrated circuit (ASIChE⑶ may include a central processing unit (CPU) and input / output (1/0) interface, E⑶ may receive input via the interface data and may generate output data .E⑶ may also have a memory, and by obtaining E⑶ input data generated and / or output data may be stored in the ECU memory.
[0033]根据基于电场的系统，电极28可以被配置为响应于患者身体20内传输的电场。 [0033] The system based on an electric field, the electrodes 28 may be configured to respond to an electric field 20 within the body of the patient transmission. 电极28可以用于感测特定位置的阻抗并将代表信号传输至外部计算机或处理器。 And transmitting a signal representing the impedance of the electrodes 28 may be used to sense a particular location to an external computer or processor. 然而，在其他示例性实施方式中，可视化、导航和/或标测系统30可包括其他类型的系统，例如且不限于:基于磁场的系统，诸如从Biosense Webster可得的CART0系统(现在以具有阻抗驱动电极和磁场驱动电极的混合形式），且如参照名称为"Intrabody Measurement"的美国专利Νο·6,498,944、名称为"Medical Diagnosis,Treatment and Imaging Systems"的美国专利No .6,788,967、以及名称为"System and Method for Determining the Location and Orientation of an Invasive Medical Instrument"的美国专利No.6,690,963中的一个或多个所大致示出的，其全部内容通过引用包含于此，或来自以色列海法的MediGuide有限公司的gMPS系统（现由St . Jude Medical公司所有），且如参照名称为"Medi cal Positioning System"的美国专利Νο·6,233,476、名称为"System for Determining the Position and Orientation of a Catheter"的美国专利No.7,197,354、以及名称为"Medical Imaging and However, in other exemplary embodiments, the visualization, navigation and / or mapping system 30 may include other types of systems, for example and without limitation: the system magnetic field based, such as the Biosense Webster available CART0 system (now having U.S. Patent No. impedance drive electrode and the field electrode driving in mixed form), and as reference entitled "Intrabody Measurement" U.S. Patent Νο · 6,498,944, entitled "Medical Diagnosis, Treatment and Imaging Systems" of No .6,788,967, and entitled " System and Method for Determining the Location and Orientation of an Invasive Medical Instrument "U.S. Patent No.6,690,963 one or more substantially illustrated, the entire contents of which are incorporated herein by reference, or from a limited MediGuide Haifa, Israel company gMPS system (now the St. Jude Medical all), and as reference entitled "Medi cal Positioning system" U.S. Patent Νο · 6,233,476, entitled "system for Determining the Position and Orientation of a Catheter" U.S. Pat. No.7,197,354, and the name "Medical Imaging and Navigation System"的美国专利Νο·7,386,339中的一个或多个所大致示出的，其全部内容通过引用包含于此。 Navigation System "U.S. Patent Νο · 7,386,339 in one or more substantially illustrated, the entire contents of which are incorporated herein by reference. 根据基于磁场的系统，导管可以被配置为包括场传感器(例如线圈），其响应于通过患者身体20传输的磁场以感测特定位置的场强并将代表信号传输至外部计算机或处理器。 The magnetic field based system, the catheter may be configured to include a field sensor (e.g. a coil), and in response to a signal representing field strength of the magnetic field transmitted through the transmission 20 for sensing the patient's body in a particular location to an external computer or processor. 该场传感器可以包括一个或多个金属线圈，金属线圈位于基于磁场的系统的导管轴杆18上或导管轴杆18内。 The field sensor may include one or more metal coils, metal coils that are located on the catheter shaft 18 or a magnetic field systems within the catheter shaft 18. 如以上所提及的，可以使用基于电场和基于磁场的系统的组合，诸如同样从Biosense Webster可得的CART03系统，且如参照名称为"Hybrid Magnetic-Based and Impedance-Based Position Sensing" 的美国专利No.7，536,218所大致示出的，其全部内容通过引用包含于此。 As mentioned above, it may be used based on a combination of electric and magnetic field-based systems, such as CART03 system also available from Biosense Webster, and as reference entitled "Hybrid Magnetic-Based and Impedance-Based Position Sensing" U.S. Pat. No.7,536,218 is illustrated generally, incorporated herein in its entirety by reference. 根据基于电场和基于磁场的系统的组合，导管可以包括作为基于阻抗的电极的两个电极28以及一个或多个磁场感测线圈。 The electric and magnetic field based on a combination of systems, may include a catheter 28 and one or more magnetic field sensing coil impedance of the two electrodes on the electrode. 还可以使用通常可得的基于荧光、计算机层析成像(CT)、以及磁共振成像(MRI)的系统。 May also be used based on the fluorescence, computer tomography (CT), and magnetic resonance imaging (MRI) systems commonly available.
[0034] 冲洗导管组件可以包括其他常规部件，诸如且不限于与电极关联的导体，以及可能的用于信号处理、可视化、定位、和/或调节的其他电子装置。 [0034] irrigation catheter assembly may include other conventional components such as a conductor and associated electrode is not limited, and may be used for signal processing, visualization, localization, and / or other electronic means for regulating. 冲洗导管组件还可以包括用于接收其他部件的多个管腔。 Irrigation catheter assembly may further comprise a lumen for receiving a plurality of other components. 仍参照图1，冲洗导管组件还可以包括电缆连接器或接口32以及手柄34。 Still referring to FIG. 1, an irrigation catheter may further include a cable assembly or connector interface 32 and a handle 34. 电缆连接器或接口32可以提供用于从栗26和/或消融系统42延伸的电缆36、38、 40的机械、液体、及电连接，如下文将更加详细描述的。 Cable connector interface 32 or 26 may be provided for Li and / or 36, 38, mechanical, fluid, and electrically connected to an ablation system 40 extending from the cable 42, as will be described in more detail. 电缆连接器或接口32可以是本领域中常规的，且可以布置在冲洗导管组件的近端。 Cable connectors or interfaces 32 may be conventional in the art, and may be disposed at the proximal end of the irrigation catheter assembly. 手柄34可以提供临床医生握持冲洗导管组件的位置，以及还可以提供用于在身体20内操纵或引导导管轴杆18的手段，如本领域所公知的。 Handle 34 may provide a clinician gripping position irrigation catheter assembly, and may also provide a means for manipulating the body 20 or the guide catheter shaft 18, as is well known in the art. 导管手柄通常是本领域中常规的，且应该理解的是，手柄的构造可以变化。 Catheter handle are generally conventional in the art, and it should be appreciated that the construction of the handle may vary. 在一个实施方式中，出于在身体20内操纵导管轴杆18的目的，手柄34可以由可控机器人致动器来替代。 In one embodiment, the catheter shaft for manipulation of the object within the body 2018, handle 34 may be actuated by a controllable robot actuator instead.
[0035] 现参照图1-4,消融电极组件10可以连接至和/或耦合至导管轴杆18。 [0035] Referring now to Figures 1-4, the ablation electrode assembly 10 may be connected to and / or coupled to the catheter shaft 18. 消融电极组件10可以在导管轴杆18远端处或其附近布置。 Ablation electrode assembly 10 may be at the distal end of the catheter shaft 18 or a shaft disposed nearby. 消融电极组件10可以布置在导管轴杆18的最远端(例如，尖端）。 Ablation electrode assembly 10 may be disposed at the most distal end (e.g., tip) of the catheter shaft 18. 现参照图2-3,根据本发明的第一实施方式，消融电极组件10可以包括电极芯构件44和电极外壳46。 Referring now to Figure 2-3, according to a first embodiment of the present invention, the ablation electrode assembly 10 may comprise an electrode core member 44 and the electrode housing 46. 消融电极组件10、电极芯构件44、电极外壳46、以及其部分的长度和/或直径可以根据消融电极组件10的设计而变化。 Ablation electrode assembly 10, electrode core member 44, electrode housing 46, and a portion of the length thereof and / or the diameter may vary depending on the design of the ablation electrode assembly 10. 在一个实施方式中，电极外壳46可以是约4毫米长。 In one embodiment, the housing electrode 46 may be about 4 millimeters long. 虽然细节上提及了四毫米，但电极外壳46的长度可以根据本发明的各种实施方式而变化。 Although details are mentioned four millimeters, but the length of the electrode housing 46 may vary in accordance with various embodiments of the present invention.
[0036]电极芯构件44被配置为将消融电极组件10耦合至导管轴杆18并用于路由各种部件至电极外壳46。 [0036] The electrode core member 44 is configured to be coupled to the ablation electrode assembly 10 to the catheter shaft 18 and the various components for routing to the electrode housing 46. 电极芯构件44具有第一端48和第二端50。 Electrode core member 44 having a first end 48 and second end 50. 根据本发明的实施方式，第一端48可以是远端，以及第二端50可以是近端。 According to an embodiment of the present invention, first end 48 may be a distal end, a second end and a proximal end 50 may be. 电极芯构件44可以通常是圆柱形。 Electrode core member 44 may be generally cylindrical. 根据本发明的实施方式，电极芯构件44的第一端48可以通常是平的。 According to an embodiment of the present invention, the electrode 44 of the first end of the core member 48 may be generally flat. 根据本发明的其他实施方式，电极芯构件44的第二端48可以是部分球形的或通常半球形的。 According to other embodiments of the present invention, the second end 48 of the electrode core member 44 may be part spherical or generally hemispherical. 虽然细节上提及了这些特定形状， 但电极芯构件44的第一端48的形状可以根据本发明的各种实施方式而变化。 Although these particular shape mentioned details, but the shape of the first end 48 of the electrode core member 44 may vary in accordance with various embodiments of the present invention. 电极芯构件44 的第二端50可以被配置为通过导管轴杆18耦合和/或连接电极芯构件44。 Second end 50 of the electrode core member 44 may be configured to couple the catheter shaft 18 and / or the core member 44 connected to the electrodes. 电极芯构件44的第二端50还可以被配置为接收液体输送管22。 Second end 50 of the electrode core member 44 may also be configured to receive a fluid delivery tube 22. 电极芯构件44可以包括多个管腔以用于接收可以穿过电极芯构件44路由的多个部件(例如，金属线等）。 Electrode core member 44 may include a plurality of lumens for receiving a plurality of members 44 may be routed through an electrode core member (e.g., metal lines, etc.). 如图3所最佳示出的，电极芯构件44还具有外表面52和内表面54。 As best shown in Figure 3, the electrode core member 44 further has an outer surface 52 and inner surface 54. 往回参照图2,电极芯构件44的外表面52可以包括用于接收热传感器58的至少一个通道56。 Referring back to FIG. 2, the outer surface 44 of the electrode core member 52 may include a thermal sensor 58 for receiving the at least one channel 56.
[0037]因此，根据如图2-3所最佳示出的本发明的实施方式，消融电极组件10可以包括至少一个热传感器58。 [0037] Thus, according to embodiment 2-3 of the present invention as best shown in FIG ablation electrode assembly 10 may include at least one thermal sensor 58. 根据本发明的实施方式，消融电极组件10可以包括三个热传感器58。 According to an embodiment of the present invention, the ablation electrode assembly 10 may comprise three thermal sensor 58. 热传感器58可以基本等间隔地围绕电极芯构件44的周围或圆周。 Thermal sensor 58 may be substantially equal around the circumference or periphery of the electrode core member 44 at equal intervals. 尽管细节上提及了基本等间隔的三个传感器，但在其他实施方式中消融电极组件10可以包括更少或更多的热传感器58,以及在其他实施方式中热传感器58的位置可以变化。 Although the three basic mentioned sensors spaced on the details, the ablation electrode assembly 10 in other embodiments may include fewer or more thermal sensors 58, and the position of the heat sensor 58 in other embodiments may vary. 例如，在一个实施方式中，单个热传感器58可以位于消融电极组件10的中心。 For example, in one embodiment, the sensor 58 may be located in a single thermal ablation assembly 10 of the center electrode. 热传感器58可以以本领域常规的任意方式连接和/或耦合至电极芯构件44(和/或消融电极组件10)从而相对于电极芯构件44(和/或消融电极组件10)保持热传感器58就位。 Thermal sensor 58 can be connected in a conventional in any manner in the art and / or coupled to the electrode core member 44 (and / or ablation electrode assembly 10) so that the electrode core member 44 (and / or ablation electrode assembly 10) holding the thermal sensor with respect to 58 place. 热传感器58被配置为用于消融电极组件10的测量和温度控制/调节。 Thermal sensor 58 is configured to measure and control the temperature of the ablation electrode assembly 10 is used / adjusted. 热传感器58可以是本领域普通技术人员公知的任何机构，例如包括但不限于热电偶和/或热敏电阻。 Thermal sensor 58 may be any means to those of ordinary skill in the art known, for example, but not limited to thermocouples and / or thermistors. 热传感器58可以包括其他类型的装置，例如包括但不限于用于确定流动液体的压力、温度和流量参数的装置，其从Radi Medical Systems AB可得，且如参照至少名称为"Combined flow,pressure and temperature sensor" 的美国专利No.RE39, 863中所大致示出的，其全部内容通过引用包含于此。 Thermal sensor 58 may comprise other types of devices, including but not limited to, for example, means the pressure of the flowing fluid, temperature and flow parameters determined, which is available from Radi Medical Systems AB, and as referring to at least entitled "Combined flow, pressure and temperature sensor "U.S. Patent No.RE39, 863 substantially as shown, the entire contents of which are incorporated herein by reference.
[0038] 热传感器58的至少一部分还可以路由通过电极外壳46。 [0038] at least a portion of the heat sensor 58 may also be routed through the electrode housing 46. 根据本发明的实施方式， 热传感器58的至少一部分可以表面安装至电极外壳46的内表面86。 According to an embodiment of the present invention, at least a portion of the thermal sensor 58 may be mounted to the inner surface of the electrode surface 86 of the housing 46. 热传感器58的至少一部分可以以本领域普通技术人员公知的任意方式表面安装至电极外壳46的内表面86。 At least a portion of the thermal sensor 58 may be surface mounted in any manner known to a person of ordinary skill in the art to the inner surface 86 of the housing 46 of the electrode. 现参照图4,电极外壳46可以包括用于接收本文所述的热传感器58的至少一部分的接收器59,其可以路由通过根据本发明实施方式的电极外壳46。 Referring now to Figure 4, electrode 46 may include a housing for receiving the thermal sensor 58 herein at least a portion of the receiver 59, which may be routed through an electrode embodiment of the invention the housing 46. 例如且非限制性地，电极外壳46可以包括翼片延伸件（未不出），其从具有至少一个接收器的电极外壳46的内表面86径向地向内延伸，通过所述至少一个接收器可以路由热传感器58的至少一部分。 For example and without limitation, the housing 46 may include an electrode tab extending member (not not), which extends radially inwardly from the inner surface of the electrode housing having at least one receiver 46, 86, via the at least one receiving may route at least a portion of the thermal sensor 58. 虽然细节上提及了翼片延伸件，但可以利用其它结构来提供接收器，通过该接收器可以路由热传感器58或任意数量的其他部件。 While the flap extensions mentioned details, but other configurations may be utilized to provide the receiver 58 can be routed to any number of thermal sensors or other components by the receiver.
[0039]电极芯构件44的内表面54限定内腔60，如最佳示出于图3。 [0039] The inner surface 54 of the electrode core member 44 defines a lumen 60, as best shown in FIG. 3 for. 在本发明的实施方式中，电极芯构件44包括冲洗通道62,其从电极芯构件44的内腔60延伸至外表面52。 In an embodiment of the present invention, the electrode core member 44 comprises a flushing channel 62 which extends from the lumen 60 of the electrode core member 44 to the outer surface 52. 在实施方式中，电极芯构件44包括多个冲洗通道62。 In the embodiment, the electrode member 44 comprises a core 62 a plurality of flushing channels. 每个冲洗通道62从电极芯构件44的内腔60延伸至电极芯构件44的外表面62。 Each flush channel 62 extending from the lumen 60 of the electrode core member 44 to the outer surface 44 of the electrode core member 62. 根据本发明的实施方式，每个冲洗通道62可以相对于电极芯构件44的第二端50更靠近电极芯构件44的第一端48定位。 According to an embodiment of the present invention, each of the processing channel 62 relative to the second end 50 of the first end 44 of the electrode 48 is positioned closer to the core member 44 of the electrode core member. 每个冲洗通道62通常可以径向向外延伸。 Each flush channel 62 may extend generally radially outwardly. 消融电极组件1 〇可以包括纵向轴64。 1 billion ablation electrode assembly 64 may include a longitudinal axis. 在一个实施方式中，每个冲洗通道62可以相对于消融电极组件10的纵向轴64约90度定向。 In one embodiment, each channel 62 may be flushed 64 is oriented approximately 90 degrees relative to the longitudinal axis of the ablation electrode assembly 10. 根据其他实施方式，一个或多个冲洗通道62可以通常朝向电极芯构件44的第一端48关于消融电极组件10的纵向轴64成锐角角度(例如， 介于约20度和约70度之间，以及在一些实施方式中，介于约30度和约65度之间）。 According to other embodiments, one or more rinsing channels 62 may generally toward the first end of the electrode core member 4864 at an acute angle with respect to the longitudinal axis of the ablation electrode assembly 10, 44 (e.g., between about 20 degrees and about 70 degrees between, and in some embodiments, between about 30 degrees and about 65 degrees). 冲洗通道62的方向根据消融电极组件10的设计而变化。 Direction flushing channel 62 varies depending on the design of the ablation electrode assembly 10. 在本发明的各个实施方式中，电极芯构件44 的冲洗通道62可以是直的或弯曲的。 In various embodiments of the present invention, the irrigation channel 62 electrode core member 44 may be straight or curved. 根据本发明的实施方式，电极芯构件44的冲洗通道62 可以绕电极芯构件44的外围或圆周彼此直径相对。 According to an embodiment of the present invention, the electrode core member 44 may be flush passage 62 around the periphery or circumference of the electrode core member 44 relative to the diameter of each other. 每个冲洗通道62可以大致是管状的并且可以沿它们的长度具有恒定直径。 Each flush channel 62 may be substantially tubular and may have a constant diameter along their length. 在一个实施方式中，每个冲洗通道62可以具有从约0.008 英寸（约0.20毫米或约1.04F)至约0.015英寸（约0.38毫米或约1.95F)大小的直径，以及对于一些实施方式，具有从约0.010英寸(约0.25毫米或约1.30F)至约0.012英寸(约0.30毫米或约1.56F)大小的直径。 In one embodiment, each of the processing channel 62 may have from about 0.008 inches (about 0.20 mm or about 1.04F) to about 0.015 inches (about 0.38 mm or about 1.95F) size diameter, and for some embodiments, having diameter from about 0.010 inches (about 0.25 mm or about 1.30F) to about 0.012 inches (about 0.30 mm or about 1.56F). 在各种实施方式中可以例如沿冲洗通道62的长度的全部或部分使用具有各种形状和直径的可替代配置。 62 along the irrigation channels may, for example In various embodiments, all or a portion of length having various diameters and shapes of alternative configurations. 每个冲洗通道62可以被配置为提供冲洗液的近侧输送。 Each flush channel 62 may be configured to provide flushing fluid conveyed proximally. 冲洗液的输送通常减少炭化、血栓形成、以及凝块形成，进而实现RF消融期间更大的能量输送。 Rinse liquid delivery generally reduces charring, thrombus formation and clot formation, and thus to achieve greater RF energy during an ablation delivery.
[0040]电极芯构件44可以包括绝热体，其具有降低的热传导性。 [0040] The core member 44 may comprise an electrode insulating member, which has a reduced thermal conductivity. 根据本发明的实施方式， 电极芯构件44可以是非热传导的。 According to an embodiment of the present invention, the electrode core member 44 may be non-heat conduction. 根据本发明的实施方式，电极芯构件44可以包括非导电材料。 According to an embodiment of the present invention, the electrode core member 44 may comprise a non-conductive material. 通常，电极芯构件44在热传导性上比电极外壳46低、并优选地大幅地低。 Typically, the electrode core member 4446 is low in thermal conductivity than the electrode housing, and preferably significantly lower. 根据本发明的实施方式，电极芯构件44可以包括降低热传导的聚合物。 According to an embodiment of the present invention, the electrode core member 44 may comprise a polymer to reduce thermal conduction. 降低热传导的聚合物是具有降低热量传输约10%或更多的物理属性的聚合物，只要其余结构部件选择以具有消融电极组件10所需的合适特征和灵敏性。 Reduce heat conduction polymer is a polymer having about 10% or more of the physical properties of reduced heat transmission, as long as the remaining structure of the member selected to have suitable features ablation electrode assembly 10 and the desired sensitivity. 一种降低热传导的材料可以包括聚醚醚酮(PEEK)。 A method of reducing the thermally conductive material may comprise polyether ether ketone (PEEK). 可以结合本发明的使用的非导热材料或降低热传导材料的其他实例包括但不限于高密度聚乙烯(HDPE)、诸如以商标IJLTEM!S)销售的并通常从General Electric Plastics(现称为SABIC Innovative Plastics)可得的那些树脂的聚酰亚胺热塑性树脂、聚芳基甲酮、聚氨酯、聚丙烯、定向聚丙烯、聚乙烯、结晶化聚对苯二甲酸乙二醇酯、聚对苯二甲酸乙二醇酯、 聚酯、聚醚酰亚胺、乙酰基、陶瓷、和/或其各种组合。 A non-thermally conductive material may be used in conjunction with the present invention, the thermally conductive material or reducing Other examples include, but are not limited to, high density polyethylene (HDPE), such as the trademark IJLTEM! S) and typically sell from General Electric Plastics (now known as SABIC Innovative Plastics) thermoplastic polyimide resin may be obtained by those resins, polyaryl ketone, polyurethane, polypropylene, oriented polypropylene, polyethylene, crystallized polyethylene terephthalate, polybutylene terephthalate glycol esters, polyesters, polyetherimides, acetyl, ceramics, and / or various combinations thereof. 在本发明的其他实施方式中，电极芯构件44还可以包括其他塑料材料，诸如硅树脂或聚醚嵌段酰胺，如以商标名PEBAX®销售的并通常从Arkema France可得的那些。 In other embodiments of the present invention, the electrode core member 44 may also include other plastic material, such as silicone or polyether block amide, such as sold under the trade name PEBAX® and is commonly available from Arkema France those.
[0041 ]电极外壳46是相对较薄的外壳，其限定内部容积，如图2-3所最佳不出。 [0041] The housing 46 is a relatively thin electrode housing defining an interior volume, no 2-3 as best shown in FIG. 电极外壳46被配置为改善电极和组织接触面之间的温度关联，这是因为它是替代实体的相对较薄外壳（即，需要较少时间使得电极外壳46记录由于施加能量所升高的温度）。 Electrode housing 46 is configured to improve the correlation between the temperature of the electrode and the tissue contacting surface, which is relatively thin because it is an alternative housing entity (i.e., less time is required so that the recording electrode housing 46 due to application of energy elevated temperature ). 电极外壳46可以是相对较薄外壳（即，具有小的厚度)并可以在电极芯构件44的第一端48的外部和/或围绕至少电极芯构件44的第一端48。 Electrode housing shell 46 may be relatively thin (i.e., having a small thickness) and may be outside of the electrode core member 48 of the first end 44 and / or around at least a first electrode core member 44 at end 48. 根据本发明的实施方式，电极外壳46可以包括单层。 According to an embodiment of the present invention, housing 46 may include a single electrode.
[0042]在实施方式中，电极外壳46的至少一部分大致可以是柔性的。 [0042] In an embodiment, at least a part of the electrode housing 46 may be substantially flexible. 例如，电极外壳46的至少一部分可被配置为符合靶组织14,并因此可以在电极外壳46与靶组织14物理接触时偏转和/或经历变形。 For example, at least a portion of the electrode housing 46 may be configured to conform to the target tissue 14, and thus may deflect and / or deform when subjected to contact with the electrode 14 of the housing 46 physically the target tissue. 特别地，电极外壳46可以足够柔韧以使得电极外壳46的至少远端部可以被配置为在相对于消融电极组件10纵向轴64的多个方向上变形和/或偏转。 In particular, the housing 46 may be sufficiently flexible electrode such that the electrode housing may be configured to at least a distal portion 46 with respect to the deformation and / or deflection in a plurality of directions to the longitudinal axis 10 of the ablation electrode assembly 64.
[0043] 现参照图4,示出了电极外壳46处于偏转的和/或变形的位置46備I，并示意性示出了以相对于轴64的角度α偏转。 [0043] Referring now to Figure 4, shown in a deflected and / or deformed positions 46 Preparation of I electrode housing 46, and schematically shows a 64 angle relative to the axis of deflection α. 虽然示出了该特定偏转，但电极外壳46可以以各种其他方式偏转和/或变形，包括在沿除了消融电极组件10的轴以外的不同轴的方向上偏转和/或变形。 While shown with this particular deflection, but the electrode housing 46 in various other ways may deflect and / or deform, it comprises a deflection and / or deformation in the direction of the shaft along different axes in addition to the ablation of the electrode assembly 10. 电极外壳46的偏转和/或变形可以允许电极外壳46符合心脏解剖结构从而改善RF消融期间的能量效率。 Deflection electrodes 46 of the housing and / or energy efficiency during RF ablation electrode deformation can allow the housing 46 conform to improve cardiac anatomy.
[0044]电极外壳46可以包括本领域普通技术人员公知的任何导电材料、和可能的导热材料，用于将消融能量输送至靶组织区域。 [0044] The electrode housing 46 may comprise any conductive material known to those of ordinary skill in the art, and may be a thermally conductive material, for ablation energy delivery to the target tissue region. 导电材料的实例包括金、铂、铱、钯、不锈钢、和/或其组合。 Examples of conductive materials include gold, platinum, iridium, palladium, stainless steel, and / or combinations thereof. 特别地，铂和铱的组合可以以各种组合使用。 In particular, the combination of platinum and iridium can be used in various combinations. 电极外壳46可以根据本领域普通技术人员公知的任意方法或技术来制造或构造。 Electrode housing 46 may be constructed or manufactured according to any method or technique known to those of ordinary skill in the art. 例如且非限制性地，电极外壳46可以使用所谓的拉深金属成形技术、金属冲压技术、电成形技术(例如，在牺牲形式上的电成形，所述牺牲形式可以包括熔化或被随后溶解的杆或其他内部形式）、粉末金属技术(例如，将粉末金属按压为金属块、以高温烧结，并然后将该按压和烧结的金属块以金属涂层构件覆盖）、液体金属注射成型(ΜΙΜ)技术，等。 For example and without limitation, the housing electrode 46 may be used a so-called deep drawing metal forming technology, metal stamping techniques, molding techniques electrical (e.g., in the form of the sacrificial electric forming, the form may include a sacrificial subsequent melting or dissolving internal lever or other form), powder metal technology (e.g., it is a metallic powder metal pressing, sintering at a high temperature, and then pressing and sintering the metal block is covered with a metal coating member), a liquid metal injection molding (ΜΙΜ) technology, and so on. 粉末金属技术还可以包括牺牲构件，以及按压和烧结的金属块可以自身传导金属涂层内部、周围以及紧靠金属涂层的液体和热能。 The powder metal techniques may further include a sacrificial member, and the pressing and sintering of the conductive metal block may themselves inside the metal coating, and thermal energy and a liquid surrounding abutting metal coating.
[0045]参照图5Α-5Β，根据电极外壳46包括金属的本发明的实施方式，电极外壳46由单个构件构成，其形成为螺旋体或螺线体，并从远端78至近端80或至少其部分延伸。 [0045] Referring to FIG 5Α-5Β, housing 46 includes an electrode according to an embodiment of the present invention, a metal electrode housing 46 constituted by a single member, which is formed in a spiral or helical body, and from the distal end to the proximal end 80 or at least 78 partially extends. 例如且非限制地，电极外壳46的至少一部分可以类似于在公开号为20 10/0 174 177、名称为"Magnetically Guided Catheter"的美国专利申请中描述和示出的尖端元件，其全部内容通过引用包含于此。 For example and without limitation, at least a part of the electrode housing 46 may be similar to 10/0 Publication No. 20 174 177, entitled "Magnetically Guided Catheter" described in the application and the tip member shown in U.S. Patent No., the entire contents of which reference herein. 再次参照图5A-5B，电极外壳46的至少一部分包括第一组凸起66,其至少部分限定对应的第一组凹槽68。 Referring again to FIGS. 5A-5B, at least a part of the electrode housing 46 comprises a first set of projections 66, which at least partially defines a first set of grooves corresponding to 68. 电极外壳46的至少一部分包括第二组凸起70,其至少部分限定对应的第二组凹槽72。 At least a portion of the electrode housing 46 comprises a second set of projections 70, which at least partially defines a second set of grooves corresponding to 72. 第一组凸起66和第二组凸起70交替间隔并且沿螺旋体或螺线体的长度在彼此相反的方向上远离电极外壳46延伸。 The first group and the second group of projections 66 are alternately spaced projections 70 and 46 extend away from the electrodes in the housing in mutually opposite directions along the length of the coil or spiral body. 特别地，第一组凸起66的每一个向近侧延伸（即，远离电极外壳46的远端78)，以及第二组凸起70的每一个向远侧延伸（即，朝向电极外壳46的远端78)。 In particular, a first set of projections each of which extends (i.e., away from the distal electrode 78 of the housing 46), and a second set of projections 70 each of which extends distally (i.e. 66 proximally, toward the electrode housing 46 the distal end 78). 第一组凸起66可以与第二组凸起70错开和/或偏离，以使得第一组凸起位于第二组凸起70之间。 The first set of protrusions 66 may be associated with a second set of staggered protrusions 70 and / or offset, such that the first set of protrusions 70 is located between the second set of projections. 第一组凹槽68和第二组凹槽72在形状上分别与第一组凸起66 和第二组凸起70的外部轮廓互补，但来自相同形状的相反成形。 The first set of grooves 68 and a second set of grooves 72 are convex outer contour 66 and a second set of protrusions 70 complementary in shape to the first set, but the same shape opposite from forming. 在图5A所示出的本发明的实施方式中，第一组凸起66、第一组凹槽68、第二组凸起70、以及第二组凹槽72中的每一个均是梯形形状的。 In an embodiment of the present invention shown in FIG. 5A, the first set of protrusions 66, a first set of grooves 68, 70 of the second set of protrusions, and a second set of grooves 72 are each a trapezoidal shape of. 虽然细节上提及了梯形形状，但根据本发明的其他实施方式，凸起66、70 和凹槽68、72可以是任意各种其他形状。 Although details are mentioned trapezoidal shape, according to other embodiments of the invention, the projections 66, 70 and recesses 68, 72 may be any of various other shapes. 例如且非限制性地，在图5B所示的本发明的实施方式中，第一组凸起66、第一组凹槽68、第二组凸起70、以及第二组凹槽72中的每一个都可以是圆形形状(例如，泪滴状)的。 For example and without limitation, in an embodiment of the present invention shown in FIG. 5B, a first set of protrusions 66, a first set of grooves 68, a second set of protrusions 70, 72 and a second set of grooves each of which may be circular in shape (e.g., teardrop shape).
[0046]可以制造电极外壳46以使得来自电极外壳46的一段的凸起66延伸至、或捕获在来自电极外壳46相邻段的凹槽72内，从而形成互锁配置。 [0046] The housing 46 may be manufactured such that the electrode projections from the segment electrode 66 of the housing 46 extends to, or captured within a recess 72 in an adjacent segment electrodes 46 from the housing, thereby forming an interlocking configuration. 另外，来自电极外壳46的一段的凸起70延伸至、或捕获在来自电极外壳46的相邻段的凹槽68内，从而形成互锁配置。 Further, the protrusion from the segment electrode 70 of the housing 46 extends to, or captured within recesses 68 of adjacent segments from the electrode housing 46, thereby forming an interlocking configuration. 因此，第一组凸起66中的至少一个被配置为与第二组凹槽72中的至少一个互锁，以及第二组凸起70中的至少一个被配置为与第一组凹槽68中的至少一个互锁。 Thus, a first set of protrusions 66 configured to at least a second group of grooves 72 at least one interlock, and a second set of protrusions 70 configured to at least one of a first set of grooves 68 and At least one interlock. 由于凸起66、70形状上分别与凹槽72、68互补并因此限定针对凸起66、70的插槽或隔室，凸起66、70在凹槽72、68内仅在预定距离上可移动。 Since the projections 66, 70 are shaped complementary to the grooves 72,68, and thus defines a slot or compartment for projections 66, 70, 66, 70 may be projections on only a predetermined distance within the grooves 72,68 mobile. 特别地，电极外壳46可定位以分别创建凸起66、70的前缘和内缘或凹槽72、 68之间的间隔或间隙74。 In particular, the electrode housing 46 may be positioned to create separate projections or recesses leading and inner edges 66, 70 72, 68 between the space or gap 74. 电极外壳46的凸起66、70和凹槽68、72沿至少超过电极外壳46-半长度延伸。 Electrodes 66, 70 of the housing projection 46 and the recess 68, 72 along at least more than half the length of the electrode extending housing 46-. 例如且非限制性地，凸起66、70和凹槽68、72沿至少电极外壳的三分之二的长度延伸。 For example and without limitation, the projections 66, 70 and recesses 68, 72 along at least two thirds of the length of the electrode extending in the housing. 尽管细节上提及了这些长度，但根据本发明的各实施方式，凸起66、70和凹槽68、72可以延伸大约电极外壳46的整个长度。 While these length details are mentioned, but in accordance with various embodiments of the present invention, the projections 66, 70 and recesses 68, 72 may extend the entire length of the housing 46 about the electrode. 例如且非限制性地，凸起66、70和凹槽68、72可以是沿电极外壳46的长度均匀间隔开的并还可以是沿电极外壳46的外围（例如，圆周）均匀间隔开的。 For example and without limitation, the projections 66, 70 and recesses 68, 72 may be along the length of the electrode housing 46 and evenly spaced apart can also periphery (e.g., circumference) of the housing along the electrode 46 evenly spaced apart. 尽管细节上提及了均匀间隔，但根据本发明的各实施方式，凸起66、70和凹槽68、72可以是沿电极外壳46的长度和/或外围不同地间隔开的。 Although details are mentioned evenly spaced, but in accordance with various embodiments of the present invention, the projections 66, 70 and recesses 68, 72 may be along the length of the electrode housing 46 and / or differently spaced apart from the periphery. 例如且非限制性地，凸起66、70和凹槽68、72可以沿电极外壳46的长度具有一致大小并且还可以沿电极外壳46的外围（例如，圆周)具有一致大小。 For example and without limitation, the projections 66, 70 and recesses 68, 72 may have the same size along the length of the electrodes and the housing 46 may also (e.g., circumference) having the same size of the housing 46 along the peripheral electrode. 尽管细节上提及了一致大小，但根据本发明的各实施方式，凸起66、70和凹槽68、72可以沿电极外壳46的长度和/或外围具有不同大小。 Although details are mentioned the same size, but in accordance with various embodiments of the present invention, the projections 66, 70 and recesses 68, 72 may be along the electrode length of the housing 46 and / or peripheral having different sizes.
[0047]由于间隙74以及还有凸起66、70和凹槽68、72的互补形状，提供了凸起66、70在凹槽68、72内的移动自由度而不会从凹槽68、72内移出。 [0047] Since the gap 74 and also a complementary shaped protrusion 66, 70 and grooves 68, 72, 66, 70 provide freedom of movement of the projection within the recess 68, 72 without the recess 68, 72 removed. 因此，电极外壳46的各段可以朝向彼此和离开彼此在预定距离内移动以分别减少和增加间隙74。 Thus, each segment electrode case 46 can be moved toward and away from each other to respectively decrease and increase in the gap 74 within a predetermined distance. 电极外壳46的各段移向彼此和远离彼此预定距离以分别减少和增加间隙74的能力可以限制电极外壳46的弯曲并限定电极外壳46的延伸范围。 Each segment electrode case 46 toward and away from each other a predetermined distance from each other to respectively decrease and increase the capacity of the gap 74 may bend limiting electrode housing 46 and defining a housing 46 of the electrode extension.
[0048]电极外壳46的各段可以相对于彼此以多种方式移动。 [0048] The housing 46 of the electrode segments can be moved relative to one another in various ways. 例如，可以压缩电极外壳46 以使得所有的间隙74闭合、或接近闭合，从而以沿纵向轴64的间隙74的累积尺寸来减少电极外壳46的纵向长度。 For example, the housing 46 may be compressed such that all the electrodes of the gap 74 is closed, or nearly closed, so that a gap 64 along the longitudinal axis 74 of the cumulative size of the electrode to reduce the longitudinal length of housing 46. 另外，电极外壳46的各段可以呈现沿纵向轴64的级联和/或顺序移动，其中一些间隙74沿纵向轴64闭合而其他间隙保持部分或完全打开。 Further, the housing 46 of the electrode segments may be presented to the longitudinal axis 64 of the cascade / or moved in order and in which some of the gaps 74 along the longitudinal axis of the gap 64 is closed while the other remains partially or fully open. 这允许电极外壳46 的任何相邻段之间的间隙74以不均匀或非一致方式打开或闭合。 This gap between any adjacent segments allow the electrode 74 to the housing 46 of non-uniform or non-uniform way open or closed. 这样，电极外壳46的外围(例如，圆周）的第一部分上的间隙7也可以闭合，而电极外壳的另一第二部分(例如，与第一部分相对)的间隙74 2可以打开。 Thus, the gap on the first portion of the periphery (e.g., circumference) of the electrode 7 of the housing 46 may be closed, and the other electrode of the second housing portion (e.g., with respect to the first portion) of the gap 742 can be opened. 该配置的结果是电极外壳46在闭合间隙7也的方向上且远离打开间隙742的方向上弯曲。 The result of this configuration is also the direction of the electrode housing 46 in the closed gap 7 and bends in a direction away from the opening 742 of the gap. 应该意识到的是，由于电极外壳46的互锁结构，移动在垂直和水平平面上可同时发生，从而至少将电极外壳46的远端弯曲和偏转至几乎无限数量的位置。 It should be appreciated that, since the electrode housing interlock structure, the mobile 46 may occur simultaneously in the vertical and horizontal plane, so that at least the distal end of the electrode housing 46 and is bent to deflect a virtually unlimited number of positions. 电极外壳46的至少一部分可以由于例如且不限于对使用中电极外壳46的外表面84的施力以所述方式偏转。 At least part of the electrode housing 46 may be used for urging the outer surface of the electrode 46 of the housing 84 due to the deflection in the manner described example and without limitation. 凸起66、70和凹槽68、72可以被配置为允许电极外壳46具有用于电极外壳46的至少一部分的变形和/或偏转的足够柔性，以允许电极外壳46符合心脏解剖结构形状，从而改善消融能量输送的能量效率。 Projections 66, 70 and recesses 68, 72 may be configured to allow deformation of the electrode housing 46 having at least a portion of the housing 46 for the electrodes and / or deflected sufficiently flexible to allow the electrode housing 46 conform to the shape of the cardiac anatomy, such improve the energy efficiency of the ablation energy delivery. 这是因为柔性电极外壳46可以在接触靶组织14时接合更大的表面积，由此改善了接触稳定性以及最优化了对靶组织14的能量输送，而同时减少了导管诱导的机械应力。 This is because the housing 46 can engage the flexible electrode larger surface area in contact with the target tissue at 14, thereby improving the contact stability and optimizing the energy delivery to the target tissue 14, while reducing mechanical stresses induced by the catheter.
[0049]可以通过本领域普通技术人员公知的激光切割技术来制造和/或产生互锁的凸起66、70和凹槽68、72。 [0049] The cutting techniques may be manufactured and / or produced interlocking projections 66, 70 and recesses 68, 72 of ordinary skill in the art known laser. 例如且非限制地，电极外壳46是由适于外科手术使用的材料(诸如导电、非腐蚀性材料)来激光切割的。 For example and without limitation, the housing electrode 46 is made of a material suitable for use in surgical procedures (such as conductive, non-corrosive material) by laser cutting. 如上所述，合适材料的实例包括金、铂、铱、钯、不锈钢、 和/或其任意组合。 As described above, examples of suitable materials include gold, platinum, iridium, palladium, stainless steel, and / or any combination thereof. 凸起66、70和凹槽68、72可以由圆柱片材料激光切割出。 Projections 66, 70 and recesses 68, 72 can be cut by a cylindrical laser sheet material. 随着电极外壳46 的螺旋数量增加，电极外壳46的柔性性能也增加。 With the increase of the number of coil electrodes 46 of the housing, the flexible properties of the electrode housing 46 also increases. 另外，随着螺旋的螺距（即，沿螺旋轴对应一圈的距离)减少，电极外壳46关于自身移动的能力增加。 Further, as the pitch of the helix (i.e., a distance corresponding to one turn along the helical axis) decreases, the electrode housing 46 on their ability to move is increased. 柔性还可以通过提供不同数量和形状的凸起66、70和凹槽68、72来调节，从而产生弯曲至不同程度以符合不同目的的电极外壳46。 Flexibility may also be adjusted by providing different numbers and shapes of the projections 66, 70 and recesses 68, 72, resulting in different degrees of bending to conform to a different object of the housing 46 of the electrode. 例如且非限制地，在电极外壳46是柔性时，相比于非柔性，RF能量可以更加明确地对准期望组织区域来用于消融程序，以及可以为医生提供额外的定位性能。 For example and without limitation, the housing 46 is a flexible electrode, as compared to non-flexible, the RF energy may be more clearly aligned to a desired region of tissue ablation procedure, and may provide additional performance for positioning a doctor.
[0050]根据本发明的另一个实施方式，其中电极外壳46包括金属，所述金属外壳46可以不包括互锁的凸起66、70和凹槽68、72，但可以替代地包括缠绕和/或编织的金属线。 [0050] According to another embodiment of the present invention, wherein the electrode comprises a metal housing 46, the housing 46 may not include a metal projections 66, 70 and recesses 68, 72 interlocked, but may alternatively comprise a winding and / or woven metal wire. 线的间隔和/或配置，包括线的相邻线匝之间的距离可以根据本发明的不同实施方式变化。 Line spacing and / or configuration, including the distance between adjacent turns of the wire may vary according to different embodiments of the present invention.
[0051]根据本发明的另一实施方式，电极外壳46可以包括聚合物材料。 [0051] According to another embodiment of the present invention, the electrode housing 46 may comprise a polymer material. 特别地，电极外壳46可以包括导电聚合物。 In particular, the housing 46 may include a conductive electrode polymer. 聚合物可以例如包括硅酮材料。 Polymers may include, for example, a silicone material. 根据本发明的实施方式，聚合物可以具有以预定密度散布于其中的导电颗粒。 According to an embodiment of the present invention, the polymer may have a density in a predetermined conductive particles dispersed therein. 导电颗粒的密度可以限定以实现期望的导电性。 Density of the conductive particles may be defined to achieve the desired conductivity. 在实施方式中，导电颗粒可以包括金属颗粒。 In an embodiment, the conductive particles may include metal particles. 例如且非限制性地，导电颗粒可以包括金属，诸如金、银、钼、铱、钛、妈、或其组合。 For example and without limitation, the conductive particles may include metals, such as gold, silver, molybdenum, iridium, titanium, mother, or a combination thereof. 电极外壳46的聚合物材料可以与公开号为2009/ 0171188、名称为"Flexible Polymer Electrode for MRI-Guided Positioning and Radio Frequency Ablation"的美国专利申请中描述和示出的聚合物材料一样，其全部内容通过引用包含于此。 U.S. Patent Application shell polymer electrode material 46 may Publication No. 2009/0171188, entitled "Flexible Polymer Electrode for MRI-Guided Positioning and Radio Frequency Ablation" described and illustrated as the polymeric material, the entire contents of incorporated herein by reference.
[0052]特别地返回参照图2-3,电极外壳46具有第一端78和第二端80。 [0052] Referring back to FIGS. 2-3 in particular, an electrode housing 46 having a first end 78 and second end 80. 根据本发明的实施方式，第一端78可以是远端，以及第二端80可以是近端。 According to an embodiment of the present invention, first end 78 may be a distal end, and a second end 80 may be proximally. 电极外壳46可以大致是圆柱形。 Electrode 46 may be substantially cylindrical housing. 根据本发明的实施方式，电极外壳46的第一端78可以是部分球形的或大致半球形的。 According to an embodiment of the present invention, a first electrode end 78 of the housing 46 may be part spherical or substantially hemispherical. 电极外壳46的第二端80可以被配置为机械连接至电极芯构件44。 A second electrode end 80 of the housing 46 may be configured to be mechanically connected to the electrode 44 of the core member. 例如且非限制性地，电极外壳46 的第二端80可以被配置为机械连接至电极芯构件44的第一端48。 For example and without limitation, a second electrode end 80 of the housing 46 may be configured to be mechanically connected to a first end 48 of the electrode core member 44. 电极外壳46可以沿相同的纵向轴64与电极芯构件44親合在一起或连接。 Electrode 64 and the housing 46 may be the parent electrode core member 44 together or connected in the same longitudinal axis. 电极芯构件44和电极外壳46可以通过任意已知的机制机械连接或耦合在一起，例如包括且不限于粘合剂结合、压合结构、扣合结构、超声铆接、机械变形、或本领域普通技术人员公知的任何其他机制。 Electrode core member 44 and the electrode housing 46 may be by any known mechanical connections or coupling mechanism together, for example, adhesive bonding including, without limitation, nip structure, the engaging structure, ultrasonic staking, mechanical deformation, or by those of ordinary techniques known to those of any other mechanism. 在实施方式中，电极外壳46可以被配置为机械连接至电极芯构件44的第一端48。 In the embodiment, the electrode housing 46 may be configured to mechanically connect to a first end 48 of the electrode core member 44. 电极芯构件44的第一端48可以具有基本等于电极外壳46的第二端80处电极外壳46内径的外径。 A first end 48 of the electrode core member 44 may have an outer diameter of the inner diameter of the electrode housing 46 at the second end 80 of the housing 46 substantially equal to the electrode. 电极芯构件44还可以在电极芯构件44的第一端48附近包括径向向外延伸的凸缘82。 Electrode core member 44 may further include a radially outwardly extending flange 82 in the vicinity of the electrode core member 48 of the first end 44. 径向向外延伸的凸缘82具有基本等于电极外壳46的近端8 0的外径的外径。 A radially outwardly extending flange 82 having an outer diameter substantially equal to the outer diameter of the proximal end of the housing 46 of the electrode 80 is.
[0053]电极外壳46还具有外表面84和内表面86，如图3所最佳不出的。 [0053] The housing 46 further has an outer electrode surface 84 and an inner surface 86, as best shown in Figure 3 is not. 在一个实施方式中，至少一个固位丝和/或安全丝(未示出）可以延伸通过导管轴杆18的管腔并可以连接至消融电极组件10。 In one embodiment, the at least one retention wire and / or safety wire (not shown) may extend through the lumen 18 of the catheter shaft and the lever may be connected to the ablation electrode assembly 10. 根据本发明的实施方式，固位丝和/或安全丝可以包括抗拉强度高的液晶聚合物(LCP)纤维丝。 According to an embodiment of the present invention, retention wire and / or a security thread may include a high tensile strength liquid crystal polymer (LCP) filaments. 固位丝和/或安全丝可以被配置为确保消融电极组件10在冲洗导管组件在身体20内移动期间不与其所附接的导管轴杆18分离。 Retention wire and / or a security thread may be configured to ensure that the ablation electrode assembly 10 in the catheter shaft 18 separated from the irrigation conduit assembly 20 during movement of the body is not attached thereto. 固位丝和/或安全丝的一端可以例如使用固定销固定在导管16内。 Retention wire and / or the end of the safety wire may be secured, for example using a pin 16 secured within the conduit. 固位丝和/或安全丝的相反端可以固定至电极外壳46。 Retention wire and / or the opposite end of the safety wire may be secured to the electrode housing 46. 特别地，固位丝和/或安全丝的至少一部分可以路由通过电极外壳46。 In particular, at least a portion of the retention wire and / or safety wire electrode may be routed through the housing 46. 根据本发明的实施方式，固位丝和/或安全丝的至少一部分可以表面安装至电极外壳46的内表面86。 According to an embodiment of the present invention, at least a portion of the retention wire and / or a security thread may be surface mounted to the inner surface 86 of the housing 46 of the electrode. 固位丝和/ 或安全丝的至少一部分可以以本领域普通技术人员公知的任意方式表面安装至电极外壳46的内表面86。 At least a portion of the retention wire and / or a security thread may be surface mounted to those of ordinary skill in any known manner to the inner surface 86 of the housing 46 of the electrode. 现参照图4,根据本发明的实施方式，电极外壳46可以包括接收器87,用于接收上面所述的可以路由通过电极外壳46的固位丝和/或安全丝的至少一部分。 Referring now to Figure 4, according to an embodiment of the present invention, the electrode housing 46 may include a receiver 87 for receiving the upper electrode can route at least a portion of the housing by the retaining element 46 and / or safety wire. 例如且非限制地，电极外壳46可以包括翼片延伸件（未不出），其从具有至少一个接收器的电极外壳46 的内表面86径向向内延伸，通过所述翼片延伸件，固位丝和/或安全丝的至少一部分可以路由并固定至电极外壳46。 For example and without limitation, the housing 46 may include an electrode tab extending member (not not), from the radially inner surface of the electrode housing having at least one receiver 46, 86 extend inwardly extending through said flap member, at least a portion of the retention wire and / or safety wire may be secured and routed to the electrode housing 46. 虽然细节上提及了翼片延伸件，但可以利用其它结构来提供接收器，穿过所述接收器可以路由热传感器58、或任意数量的其他部件。 While the flap extensions mentioned details, but other configurations may be utilized to provide a receiver, the receiver can route through 58, or any number of other components of the thermal sensor. 固位丝和/或安全丝可以通过在固位丝和/或安全丝的末端打结并将打结端压合至接收器87从而固定至电极外壳46。 Retention wire and / or at the end of the security thread by retaining wires and / or knot security thread and knotted to the end of the nip 87 such that the receiver housing 46 fixed to the electrode. 然后可以施加粘合剂来将打的结以及固位丝和/或安全丝结合至接收器87中。 The adhesive may then be applied to the knot and retaining filaments and / or a security thread incorporated into the receiver 87.
[0054]根据本发明的实施方式，堵塞物和/或气囊88可以被配置为填充电极外壳46所限定的内部容积。 [0054] According to an embodiment of the present invention, the plug and / or balloon 88 may be configured to define an internal volume 46 is filled electrode housing. 在本发明的一些实施方式中，堵塞物和/或气囊88还可以为电极外壳46提供稳定性并维持对偏转的一定程度的阻力（即，恢复力）。 In some embodiments of the present invention, the plug and / or balloon 88 can also provide stability to the electrode housing 46 and maintain a certain degree of resistance to the deflection (i.e., resilience). 堵塞物和/或气囊88最佳示于图3。 Plug and / or balloon 88 is shown best in FIG. 根据本发明的实施方式，堵塞物和/或气囊88可以包括聚合物。 According to an embodiment of the present invention, the plug and / or balloon 88 may comprise a polymer. 例如且非限制地，所述聚合物可以包括硅酮。 For example and without limitation, the polymer may comprise silicone. 根据本发明的实施方式，堵塞物和/或气囊88可以相对较软。 According to an embodiment of the present invention, the plug and / or balloon 88 may be relatively soft. 例如且非限制地，堵塞物和/或气囊88的硬度可以基于最终用户的消融电极组件10的期望特征修改和/或调节以提供变化的柔性度。 For example and without limitation, a plug the hardness and / or balloon 88 may be modified based on the desired characteristics of the final user and ablation electrode assembly 10 and / or adjusted to provide varying degree of flexibility. 换言之，堵塞物和/或气囊88可以具有预定硬度以实现期望柔性。 In other words, plug and / or balloon 88 may have a predetermined hardness to achieve the desired flexibility. 堵塞物和/或气囊88可以被配置为阻止血液和/或液体进入电极外壳46所限定的容积内。 Plug and / or balloon 88 may be configured to prevent blood and / or liquid into the electrode casing 46 defining a volume. 在本发明的实施方式中，电极外壳46与堵塞物和/或气囊88可以彼此紧邻和/或直接邻接。 In an embodiment of the present invention, the electrode 46 and the plug housing and / or balloon 88 may be next to each other / and or directly adjacent. 根据本发明的其他实施方式，电极外壳46与堵塞物和/或气囊88可以在它们之间限定间隙。 According to other embodiments of the present invention, the electrode and the plug housing 46 and / or balloon 88 may define a gap therebetween. 该间隙的配置可以很大地变化并可以是规则或不规则的，以及在本发明的一些实施方式中可以包括支撑构件(例如，凹槽、凸台和小柱等）以维持电极外壳46与堵塞物和/或气囊88之间的间隔。 The configuration of the gap may vary greatly and may be regular or irregular, and in some embodiments of the present invention may comprise a support member (e.g., grooves, projections and cartridge, etc.) and the sustain electrode 46 and the clogging of the housing the interval between 88 and / or balloon. 根据本发明的实施方式，该间隙可以被配置为环形间隙。 According to an embodiment of the present invention, the gap may be configured as an annular gap.
[0055]电极外壳46可以电连接至消融系统42以允许输送消融能量等。 [0055] The electrode 46 may be electrically connected to the housing the ablation system 42 to allow delivery of ablation energy and the like. 电极外壳46可以以本领域的任意常规方式电连接至消融系统42。 Electrode 46 may be connected to the housing 42 in a conventional electrical ablation system in any embodiment of the present art. 例如，可以在消融电极组件10的电极芯构件44和电极外壳46内设置电源线90(最佳示出于图2-3)。 For example, the power supply line 90 may be provided within the electrode core member of the ablation electrode 44 and the electrode assembly 10 the housing 46 (best shown for FIGS. 2-3). 电源线90可以延伸穿过设置在消融电极组件10内的管腔。 Power line 90 may extend through a lumen disposed within the ablation electrode assembly 10. 根据本发明的实施方式，电源线90的至少一部分可以表面安装至电极外壳46的内表面86。 According to an embodiment of the present invention, at least part of the power supply line 90 may be mounted to the surface of the electrode inner surface 86 of the housing 46. 电源线90的至少一部分可以以本领域普通技术人员公知的任意方式表面安装至电极外壳46的内表面86。 At least part of the power supply line may be surface mounted to the inner surface 86 of the housing 46 of the electrode 90 to those of ordinary skill in the art and any known manner. 再次参照图4,根据本发明的实施方式，电极外壳46可以包括接收器91，用于接收上面所述的可以路由通过电极外壳46的电源线90的至少一部分。 Referring again to FIG. 4, according to an embodiment of the present invention, the electrode housing 46 may include a receiver 91 for receiving the above may be routed through at least part of the electrode power supply line 46 of the housing 90. 例如且非限制性地，电极外壳46可以包括翼片延伸件(未不出），其从电极外壳46的内表面86径向向内延伸，通过所述翼片延伸件可以路由电源线90的至少一部分。 For example and without limitation, the housing 46 may include an electrode tab extending member (not not), which from the inner surface of the electrode 46 of the housing 86 extends radially inwardly extending through the flap member 90 of the power supply lines may be routed at least a part of it. 虽然细节上提及了翼片延伸件，但可以利用其它结构来提供接收器，穿过所述接收器可以路由电源线90、 或任意数量的其他部件。 While the flap extensions mentioned details, but other configurations may be utilized to provide a receiver, the receiver can be routed through the power cord 90, or any number of other components.
[0056] 返回参照图1，消融系统42例如包括消融发生器92和一个或多个消融贴片电极94。 [0056] Referring back to Figure 1, an ablation system 42 comprising, for example, an ablation generator 92 and the one or more ablation electrodes 94 patches. 消融发生器92特别地通过冲洗导管组件及其消融电极组件10的电极外壳46生成、输送并控制消融能量(例如，RF)输出。 Ablation generator 92 generated by the particular irrigation catheter ablation electrode assembly and the electrode assembly 10 of the housing 46, and controls the ablation energy delivery (e.g., the RF) output. 发生器92在本领域中是常规的，并可包括从St. Jude Medical 公司商业上可得的、以型号IBI-1500T RF心脏消融发生器销售的单元。 Generator 92 are conventional in the art, and may include at St. Jude Medical from commercially available, under model IBI-1500T RF cardiac ablation generator units sold. 在示例性实施方式中，发生器92可以包括RF消融信号源96,其被配置为生成消融信号，所述消融信号输出通过一对源连接器:正极连接器源(+)，其可以电连接至冲洗导管组件的消融电极组件10的电极外壳46;以及负极连接器源(-)，其可以电连接至一个或多个贴片电极94。 In an exemplary embodiment, the generator 92 may include an RF ablation signal source 96, which is configured to generate a signal of an ablation, the ablation source signal is output through a pair of connectors: connector source positive (+), which can be electrically connected housing the electrode assembly to the irrigation catheter ablation electrode assembly 10, 46; and a cathode connector source (-), which can be electrically connected to one or more patch electrodes 94. 应该理解的是，这里所使用的术语连接器不意味着一种特定类型的物理接口机构，而是广泛地被设想为表示一个或多个电气节点(包括多路复用和解复用节点）。 It should be understood that the terminology used herein is not meant to connect a particular type of physical interface mechanism, but broadly conceived to represent one or more electrical nodes (node ​​comprises multiplexing and demultiplexing). 源被配置为根据一个或多个用户指定控制参数(例如，功率、时间等）以及在各种反馈感测和控制电路的控制下来生成预定频率的信号。 Source is configured to specify a control parameter (e.g., power, time, etc.) in accordance with one or more user and generating a control signal at a predetermined frequency in a variety of sensing and feedback control circuit is off. 所述源可以针对RF能量生成例如约450kHz或更大频率的信号。 The source signal of about 450kHz or greater, for example, may be generated for the frequency of RF energy. 所述发生器92还可以监控与消融程序相关的各种参数，例如包括阻抗、冲洗导管组件的远尖端的温度、施加的消融能量、功率、施力、接近度、以及冲洗导管组件的位置，并且提供关于这些参数的反馈至临床医生或冲洗导管组件内的其他部件。 The generator 92 may also monitor the various parameters related to an ablation procedure, including an impedance, for example, flushing the catheter assembly distal tip temperature, ablation energy is applied, the power, force, proximity, and flushing the catheter assembly position, these parameters and provide feedback to the clinician or other components within the irrigation catheter assembly.
[0057]仍然参照图1，消融系统42还可以包括控制系统98。 [0057] Still referring to Figure 1, an ablation system 42 may further include a control system 98. 控制系统98被配置为确定靶组织14(即，待消融组织）的温度和/或恰当的消融技术。 Control system 98 is configured to determine the target tissue 14 (i.e., to be ablated tissue) temperature and / or the appropriate ablation technique. 消融电极组件10的电极外壳46可以通过导线连接至控制系统98。 Electrode ablation electrode assembly 46 the housing 10 may be connected to control system 98 via a wire. 根据一些实施方式，消融发生器92可以形成控制系统98的一部分，或在其他实施方式中与控制系统98分离。 According to some embodiments, an ablation generator 92 may form part of the control system 98, or separate from the control system 98 in other embodiments. 热传感器58可以连接至控制系统98。 Thermal sensor 58 may be connected to the control system 98. 例如且非限制性地，导线可以延伸穿过导管内的管腔。 For example and without limitation, the wire may extend through a lumen within the catheter. 用于确定流动液体的压力、温度和流量参数的装置从Radi Medical Systems AB可得，且如至少参照名称为"Combined flow,pressure and temperature sensor"的美国专利No · RE39，863中所大致示出的，其全部内容通过引用包含于此，该装置可以使用这里所述的或本领域普通技术人员公知的根据流量的压力算法来监测和/或控制导管内或来自导管一个或多个位置的冲洗液的流量。 For determining the pressure of the flowing liquid, means the temperature and flow parameters can be obtained from Radi Medical Systems AB, and as referring to at least entitled "Combined flow, pressure and temperature sensor" U.S. Patent No · RE39,863 substantially as shown , the entire contents of which are incorporated herein by reference, may be used the apparatus described herein or well known to those of ordinary skill in the art to monitor and / or control conduit or conduits from one or more positions according to the pressure of the flush flow algorithm fluid flow. 这些用于确定流动液体的压力、温度、和流量参数的装置也可以连接至控制系统98。 The means for determining the pressure of the flowing liquid, device temperature, and flow parameters may also be connected to the control system 98. 通过控制系统98增加消融周期期间能量输送的功率和/或长度(例如，幅度和/或操作时间），可以增加提供给消融电极组件10的能量。 By increasing the power control system 98 and / or length (e.g., amplitude and / or operating time) during an ablation energy delivery period, you can increase the power supplied to the ablation electrode assembly 10. 通过减少消融周期期间能量输送的功率和/或时间长度(例如，频率和/或操作时间），可以减少提供给消融电极组件10的能量。 By reducing the power and / or length of time during the ablation energy delivery period (e.g., frequency and / or operating time) can be reduced to provide ablation energy to the electrode assembly 10. 由控制系统98选择的消融技术可以被选择以在靶组织14内产生一定的、预定温度，其将形成靶组织14内的期望损伤。 Selected from the ablation control system 98 may be selected to produce a certain, predetermined temperature in the target tissue 14, which will form a desired target tissue injury within 14. 虽然在一些实施方式中期望的损伤可以是透壁的，然而期望损伤的特征可以极大地变化。 While it is desirable in some embodiments may be transmural injury, however, damage to the desired features may vary greatly. 在靶组织14 内形成期望损伤的靶组织14内的一定、预定温度可以由靶组织的热响应影响。 Forming a desired target tissue damage in certain target tissues 14, the predetermined temperature may affect the thermal response within the target tissue 14. 靶组织14的热响应可以由多个变量影响，包括组织厚度、脂肪和肌肉量、通过该区域的血流、以及消融电极组件10和靶组织14的接触面的血流。 Thermal response can affect the target tissue 14 by a plurality of variables, including the thickness of the tissue, fat and muscle mass, blood flow through the region, and ablation electrode assembly 10 and the target tissue blood contacting surface 14.
[0058] 返回参照图2-4,根据本发明的实施方式，消融电极组件10还包括冲洗液分配元件100。 [0058] Referring back to FIGS. 2-4, according to an embodiment of the present invention, the ablation electrode assembly 10 further includes a flushing fluid distribution element 100. 根据本发明的实施方式，冲洗液分配元件100可以被配置为大致环孔。 According to an embodiment of the present invention, the rinse liquid distribution element 100 may be configured as a substantially annular ring. 冲洗液分配元件1〇〇具有第一端102和第二端104。 1〇〇 irrigation distribution element 102 having a first end and a second end 104. 根据本发明的实施方式，第一端102可以是近端，以及第二端104可以是远端。 According to an embodiment of the present invention, the first end 102 may be a proximal end, and a second distal end 104 may be. 冲洗液分配元件100的第一端102的至少一部分可以啮合导管轴杆18,电极芯构件44可以位于导管轴杆18中。 Flushing fluid distribution element 102 at least a portion of the first end 100 may engage the catheter shaft 18, the electrode 44 may be located in the core member 18 in the catheter shaft. 根据本发明的实施方式，冲洗液分配元件100的第二端104的至少一部分可以围绕和/或环绕电极芯构件44的至少一部分，以及还可以在冲洗液分配元件100和电极芯构件44之间限定环形冲洗端口106。 According to an embodiment of the present invention, the rinse liquid distribution element 100 of the second end 104 may surround at least a portion of and / or around at least a portion of the electrode core member 44, and also between the rinse liquid distribution element 100 and the electrode core member 44 defining an annular flushing port 106.
[0059]冲洗液分配元件100被配置为围绕并沿着电极外壳46的外表面84引导冲洗液至电极外壳46，以及具体地，引导液体(例如，冲洗液)在与电极外壳46的外表面84基本平行的方向上流动。 [0059] The rinse liquid distribution element 100 is configured to surround the electrode and along the outer surface 84 of housing 46 to guide the rinsing liquid to the electrode housing 46, and in particular, to guide the liquid (e.g., the rinse liquid) in the outer surface of the electrode 46 of the housing 84 flows in a direction substantially parallel. 冲洗液分配元件100可以包括液体成形构件108,其帮助确保液体趋于流向消融电极组件10的电极外壳46的表面84。 Flushing fluid distribution element 100 may comprise a liquid forming member 108, which helps ensure that the liquid tends to flow to the ablation electrode case 10 of the electrode assembly 84 of the surface 46. 例如且非限制地，冲洗液分配元件100的液体成形构件108可以包括冲洗液分配元件100表面上限定环形冲洗端口106的通道、膛线、凸台、隆起、斜面、和/或其组合。 For example and not limitation, the liquid dispensing device 100 of the rinse liquid molding member 108 may include a flushing channel defining an annular port 106, the rifling, bosses, ridges 100 on the surface of the rinse liquid distribution element, slope, and / or combinations thereof. 液体成形构件108被配置为干扰液体流动(例如，使得更靠近电极芯构件44的外表面52流动的液体相对于远离电极芯构件44的外表面52流动的液体流得慢），进而帮助确保液体趋于流向电极外壳46的表面84。 Liquid shaped member 108 is configured to interfere with the liquid flow (e.g., such that 52 the liquid flowing the outer surface is closer to the electrode core member 44 52 liquid flowing an outer surface remote from the electrode core member 44 flows slowly relative), thus help ensure that the liquid It tends to flow to the electrode surface 84 of the housing 46. 这样，冲洗液的流动可以是湍流从而邻近消融电极组件10的电极外壳46的外表面84提供包络流模式，以用于混合、转移和/或稀释与消融电极组件10接触的血液，从而帮助阻止停滞及凝块形成。 Thus, the rinsing liquid flow may be turbulent so that the ablation electrode adjacent the electrode assembly 10 the housing outer surface 84 of the envelope 46 providing streaming mode, for mixing, transfer and / or diluted with a blood contact ablation electrode assembly 10, thereby helping prevent stagnation and clot formation. 虽然电极外壳46的弯曲可以影响冲洗液的流动，但应该预料的是，根据本发明实施方式的电极外壳46的弯曲将不具有大的临床影响，这是因为电极外壳46的任意弯曲和/或偏转都是有限的并且相对较小的。 Although the curved electrode case 46 may affect the irrigation fluid flow, it is to be expected that the electrode according to the housing embodiment of the present invention is bent 46 will not have a major clinical impact, because the electrode can be bent 46 and / or deflection is limited and relatively small. [0060]冲洗液分配元件100的配置可以改进冲洗液的液体流动，以使得冲洗液的总流速(或每单位时间输送的体积)对比于传统冲洗流速(和体积)可以非常地低。 [0060] Configuration irrigation distribution element 100 can improve the flow of liquid flushing fluid, so that the total flow rate (or the volume delivered per unit time) in contrast to conventional rinse liquid flushing flow (and volume) can be very low. 换言之，冲洗液的整体的总液体体积可以远低于现有技术或远低于临床实践中通常利用的那些液体体积， 这对于已经遭受过多液体负荷的患者(例如，患有心力衰竭等的患者)来说尤其有价值。 In other words, the rinsing liquid overall total liquid volume may be far below or far lower than those of the prior art liquid volume normally utilized in clinical practice, for patients already suffering from which excess fluid load (e.g., with heart failure, etc. ) is especially valuable for patients. 整体的总液体体积可以低至每分钟个位数毫升至约10左右毫升，而同时有效地减少或消除了炭化和凝块，以及改善了用于精确功率控制的温度关联以维持消融术期间的温度。 The total volume of the entire liquid can be as low as single digit ml per minute to about 10 milliliters, while effectively reducing or eliminating the clot and charring, and associated improved temperature for precise power control to maintain during the ablation temperature.
[0061 ] 阀构件，例如且非限制性地，诸如在公开号为2008/0161795、名称为"Irrigated Ablation Catheter System With Pulsatile Flow To Prevent Thrombus" 的共有美国专利申请中所示出和描述的，其全部内容通过引入包含于此，或其他类似的流量控制特征，可以与包含消融电极组件1 〇的导管一起使用以改变冲洗液的流速。 There are shown and described in U.S. Patent Application [0061] a valve member, for example and without limitation, such as Publication No. 2008/0161795, entitled "Irrigated Ablation Catheter System With Pulsatile Flow To Prevent Thrombus" in which by introducing the entire contents of which are incorporated herein, or other similar flow control features can be used with catheter ablation comprising an electrode assembly square to change the flow rate of the flushing fluid. 在其他实施方式中，流量控制特征可以是与导管分离并协同导管一起使用的辅助控制系统的一部分。 In other embodiments, the flow control feature may be a separate part of the catheter and the auxiliary control system for use with a catheter synergistic. 阀可以自动地运转而无需用户输入，和/或可以通过可视化、导航和/或标测系统30的ECU基于RF消融期间所记录的反馈来运转。 Valve may be automatically operated without user input, and recorded during the feedback / or may be visualized, the ECU navigation and / or mapping system 30 to operate based on RF ablation. 反馈可以例如且非限制地涉及时间、温度、和/或阻抗。 Feedback may for example and without limitation, to time, temperature, and / or impedance. 用于在控制算法中自动执行反馈的电路可以通过本领域普通技术人员在熟悉本文的教导后容易地设置。 A feedback circuit for automatic execution of the control algorithm can be easily provided by the familiar with the teachings herein, those of ordinary skill in the art. [0062]现参照图6-7,根据本发明的第二实施方式，消融电极组件10'可以包括电极芯构件44'和电极外壳46'。 [0062] Referring now to FIGS. 6-7, according to a second embodiment of the present invention, the ablation electrode assembly 10 'may include an electrode core member 44' and the electrode housing 46 '. 根据本发明第二实施方式的消融电极组件10'可以与上文所述的消融电极组件10基本相同，包括在实施方式中通常是柔性的电极外壳46'（例如，在电极外壳46'开始与靶组织14物理接触时，被配置为通过偏转和/或变形来符合靶组织14)，但是电极芯构件4 4 '和/或电极外壳4 6 '可以被修改为提供冲洗液的远端运输，其中冲洗液的至少一部分被输送至远端排出端口。 The ablation electrode assembly of the second embodiment of the present invention, 10 'may be substantially identical to the ablation electrode 10 assembly described above, in the embodiment includes a generally flexible electrodes in the housing 46' (e.g., the electrode housing 46 'begins with when physical contact with the target tissue 14, is configured to deflect and / or deform to conform to the target tissue 14), but the electrode core member 44 'and / or the electrode housing 46' may be modified to provide the distal end of the rinse liquid transport, wherein at least a portion of the rinse liquid is delivered to the distal end of the discharge port. 被配置为提供冲洗液的近侧输送和远侧输送的消融电极组件10'会尤其有益于减少消融电极组件10'的远端(例如，尖端)的血栓形成和/或炭化。 It is configured to provide flushing fluid delivery and a proximal ablation electrode distal delivery assembly 10 'may be particularly beneficial in reducing the ablation electrode assembly 10' of the distal end (e.g., tip) thrombosis and / or charring. 通过提供冲洗液的近侧和远侧输送，还可以在消融电极组件10'的电极外壳46'的邻近区域中转移血液以及阻止停滞。 Blood transferred 'electrode housing 46' by providing a region adjacent to the proximal and distal rinse liquid delivery may also be in the ablation electrode assembly 10 and preventing stagnation.
[0063]仍然参照图6-7,消融电极组件10'被配置为通过从电极芯构件44'的内部空腔60' 至电极外壳46 '的第一端78 '延伸的轴向延伸通道110来用于冲洗液的远侧输送。 [0063] Still referring to FIGS. 6-7, the ablation electrode assembly 10 'is configured by a core member from the electrode 44' of the inner cavity 60 'to the electrode housing 46' a first end 78 'extending axially extending channel 110 for distal flushing fluid delivery. 轴向延伸通道110可以限定为大致圆柱构件112。 An axially extending passageway 110 may be defined as a generally cylindrical member 112. 根据本发明的各个实施方式，大致圆柱构件112可以与内部芯构件44'一体。 According to various embodiments of the present invention, the cylindrical member 112 may be substantially 44 'integrally with the interior core member. 根据本发明的各个其他实施方式，大致圆柱构件112还可以与内部芯构件44'分离。 According to various other embodiments of the present invention, a substantially cylindrical member 44 may also be 112 'separated from the interior core member. 例如且非限制地，大致圆柱构件112可包括闭合缠绕线圈弹簧，其具有低硬度聚合物的衬垫或护套。 For example and without limitation, a generally cylindrical member 112 may comprise a coil spring wound closure, gasket or a sheath having a low durometer polymer. 又例如，大致圆柱构件112可包括聚合物管。 As another example, a substantially cylindrical tube member 112 may comprise a polymer. 圆柱构件112可以是充分柔性的，以使得圆柱构件112的至少一部分可被配置为相对于消融电极组件10的纵向轴64在多个方向上变形和/或偏转。 Cylindrical member 112 may be substantially flexible, such that at least a portion of the cylindrical member may be arranged to be deformed in a plurality of directions 64 and / or deflection of the ablation electrode to the longitudinal axis 10 of the assembly 112. 尽管构件112被限定为大致圆柱形的，但根据本发明的实施方式，构件112可以包括多种不同形状。 While member 112 is defined as a substantially cylindrical, according to an embodiment of the present invention, member 112 may include a variety of different shapes. 根据本发明的另一个实施方式，轴向延伸通道110 可以限定为布置在堵塞物和/或气囊88中的贯通孔，所述堵塞物和/或气囊88被配置为填充电极外壳46所限定的内部容积。 According to another embodiment of the present invention, axially extending channel 110 may be defined as a plug disposed in and / or through-holes in the airbag 88, the plug and / or balloon 88 is configured to fill the housing 46 defined by the electrodes internal volume. 如上面所述的，根据本发明的实施方式，堵塞物和/或气囊88可以包括硅酮。 As described above, according to an embodiment of the present invention, the plug and / or balloon 88 may include silicone. 圆柱构件112和/或堵塞物和/或气囊88的总偏转范围可以相对较小，以使得导管上的应力预期不会不利地影响消融电极组件10'的功能。 The cylindrical member 112 and / or blockages total deflection range and / or balloon 88 may be relatively small, so that the expected stress on the catheter without adversely affecting the function of the ablation electrode assembly 10 '.
[0064]根据本发明的一个实施方式，轴向延伸通道110可以延伸至电极外壳46'的远端78'。 [0064] According to an embodiment of the present invention, axially extending channel 110 may extend to the electrode housing 46 'of the distal end 78'. 根据本发明的另一个实施方式，如图6-7所大致示出的，轴向延伸通道110可以在构件112的远端116附近过渡到一个或多个端口114。 According to another embodiment of the present invention, substantially as shown in Figure 6-7, the axially extending channel 110 can transition to one or more ports 114 near the distal end 116 of member 112. 端口114可以被配置为使得流经轴向延伸通道110的冲洗液流至电极外壳46'的第一端78'，在其中充分地冲洗消融电极组件10'的电极外壳46'的第一端78'（例如，尖端）。 Port 114 may be configured such that the flow through the axially extending passage of the housing 46 to an electrode rinse stream 110 'of the first end 78', in which is sufficiently irrigated ablation electrode assembly 10 'of the housing electrode 46' of the first end 78 '(e.g., tip). 例如且非限制性地，构件112可以包括三个端口114。 For example and without limitation, member 112 may include three ports 114. 每个端口114可以相对于消融电极组件10'的纵向轴64大致成锐角（例如，约45度)定向。 The longitudinal axis 64 with respect to each port 114 may ablation electrode assembly 10 'is substantially at an acute angle (e.g., about 45 degrees) orientation. 端口114的定向根据消融电极组件10'的设计而变化。 Directional port 114 varies depending on design ablation electrode assembly 10 '. 在本发明的实施方式中，端口114可以围绕构件112的圆周基本等距地间隔。 In an embodiment of the present invention, port 114 may be substantially equally spaced around the circumference of the member 112. 端口114可以被配置为从轴向延伸通道110的远端延伸至电极外壳46'的远端78'。 Port 114 may be configured to extend axially from the distal end of the channel 110 extends to the electrode housing 46 'of the distal end 78'.
[0065]根据本发明的实施方式，涂层(未示出）可以布置在构件112的至少一部分上，构件112限定轴向延伸通道100。 [0065] According to embodiments of the present invention, a coating (not shown) may be disposed on at least a portion of the member 112, the member 112 defines a passageway 100 extending axially. 例如且非限制性地，在构件112不与内部芯构件44'一体形成并替代地包括导电材料时，涂层会是尤其有用。 For example and without limitation, when the member 112 is not 'formed integrally with the interior core member 44 and instead include a conductive material, the coating may be particularly useful. 涂层可以包括非导电材料。 The coating may comprise a non-conductive material. 例如且非限制性地，涂层可以包括金刚石、类金刚石碳（DLC)、或通常由EIdu Pont de Nemours and Company以商标TEFLON®市售的聚四氟乙烯(PTFE)。 For example and without limitation, coating may include diamond, diamond-like carbon (the DLC), or generally by the EIdu Pont de Nemours and Company marketed under the trademark TEFLON® polytetrafluoroethylene (PTFE). 在本发明的实施方式中，涂层可以绕轴向延伸通道110的整个周边并沿整个长度设置。 In an embodiment of the present invention, the coating may extend around the entire periphery of the axial passage 110 and is provided along the entire length. 然而，根据本发明的各个实施方式，涂层可以仅绕轴向延伸通道110的部分周边和/或仅沿部分长度设置。 However, according to various embodiments of the present invention, a coating may extend the peripheral portion and / or only partially along the length of the channel 110 is provided only around the axial direction. 围绕轴向延伸通道110 的周边和/或长度或其一部分设置的涂层量可以根据消融电极组件10'的相对需求而变化。 Peripheral and / or the length or a portion thereof extending in the amount of coating disposed about the axial channel 110 may vary depending on the relative needs of the ablation electrode assembly 10 '. [0066]虽然消融电极组件10、10'描述并示出具有单个电极芯构件44、44'和单个电极外壳46、46'，但根据本发明的各个实施方式，消融导管16可以包括两个或更多个电极芯构件44、44'和/或两个或更多个电极外壳46、46'。 [0066] While the ablation electrode assemblies 10, 10 'described and illustrated with a single electrode core member 44, 44' and a single electrode case 46, 46 ', but in accordance with various embodiments of the present invention, ablation catheter 16 may comprise two or more electrode core member 44, 44 'and / or two or more housing electrodes 46, 46'. 此外，虽然消融电极组件10、10'描述并示出为使得电极外壳46、46'在电极芯构件44、44'的远侧定位，但根据本发明的各个实施方式，至少一个电极外壳46、46'可以在电极芯构件44、44'的近侧定位。 Further, although the ablation electrode assemblies 10, 10 'as described and illustrated that the electrode housing 46, 46' positioned at the distal electrode core member 44, 44 ', but the embodiment according to various embodiments of the present invention, the at least one electrode housing 46, 46 'may be in the electrode core member 44, 44' positioned proximally.
[0067] 例如且非限制性地，消融电极组件10''可以包括两个或更多个电极芯构件44^442 以及单个电极外壳46' '，如图8所大致不出的。 [0067] For example and without limitation, the ablation electrode assembly 10 'may include two or more electrode core member 44 and the individual electrodes 442 ^ housing 46', as shown in FIG 8 is substantially undetectable. 第一电极芯构件44ι可以布置在相对于电极外壳46的近侧。 The first electrode may be disposed on the core member 44ι proximal housing 46 relative to the electrode. 第一电极芯构件44ι可以与上面所述的电极芯构件44、44'基本相同。 44ι first electrode core member and the upper electrode may be of the core member 44, 44 'is substantially the same. 第二电极芯构件44 2可以布置在相对于电极外壳46的远侧。 The second electrode core member 442 may be disposed distally of the housing 46 relative to the electrode. 第二电极芯构件442可以与上面所述的电极芯构件44、44'基本相同，然而，第二电极芯构件44 2被定向为使得第一和第二电极芯构件4也、442以相反方向面对。 The second electrode 442 may be a core member of the core member and the upper electrode 44, 44 'is substantially the same, however, the second electrode 442 of the core member is oriented such that the first and second electrode core member 4 is also, in the opposite direction 442 face. 因此，第二电极芯构件442的第一端482可以是近端，第二电极芯构件442的第二端（未示出）可以是远端。 Thus, the second electrode 442 of the first core member 482 may be a proximal end, a second end of the second electrode core member (not shown) may be the distal end 442. 电极外壳46''可以与上面所述的电极外壳46基本相同。 Housing electrode 46 '' may be substantially the same as 46 above the electrode housing. 电极外壳46''可以是大致圆柱形，以及电极外壳46''的第一和第二端78''、80''可以是开口的。 Housing electrode 46 '' may be substantially cylindrical, and an electrode housing 46 'of the first and second ends 78' ', 80' 'may be open. 特别地，电极外壳46''的第一端78''可以被配置为连接至定位在电极外壳46'' 的远侧的第二电极芯构件44 2,以及电极外壳46''的第二端78''可以被配置为连接至定位在电极外壳46' '的近侧的第一电极芯构件44ι。 In particular, the housing electrode 46 'of the first end 78' 'may be configured to be connected to an electrode positioned in the housing 46' of the core member distal second electrode 442, and the electrode housing 46 'second end' of the 78 '' may be configured to be connected to an electrode positioned in the housing 46 'of the first electrode core member proximal 44ι' is.
[0068]图8中所大致示出的消融电极组件10''还可以包括两个或更多个冲洗液分配元件100^1002。 Ablation electrode assembly [0068] FIG. 8 shows generally 10 '' may also comprise two or more flushing fluid dispensing device 100 ^ 1002. 冲洗液分配元件100^1002可以与上面所述的冲洗液分配元件100基本相同。 Flushing fluid dispensing device 100 ^ 1002 may assign member above the rinsing liquid 100 is substantially the same. 第一冲洗液分配元件1004^第一端102:的至少一部分可以啮合其中布置第一电极芯构件4和的导管轴杆18。 A first rinsing liquid dispensing end of the first element 1004 ^ 102: wherein at least a portion of the arrangement of the first electrode may engage the core member 4 and the catheter shaft 18. 第一冲洗液分配元件100j^第二端10也的至少一部分可以围绕和/或环绕第一电极芯构件4也，以及还可以在第一冲洗液分配元件10(h和电极芯构件4和之间限定环形冲洗端口106:。环形冲洗端口1061被配置为朝向电极外壳46''引导冲洗液，以及进而向远侧引导冲洗液。第二冲洗液分配元件1〇〇2的第一端1〇22的至少一部分可以啮合尖端电极118。 根据本发明的各个实施方式，尖端电极118可以是或不是柔性的。第二冲洗液分配元件100 2 的第二端1〇42的至少一部分可以围绕和/或环绕第二电极芯构件442,以及还可以在第二冲洗液分配元件1〇〇2和第二电极芯构件442之间限定环形冲洗端口1062。环形冲洗端口1062被配置为引导冲洗液朝向电极外壳46' '，以及进而向近侧引导冲洗液。冲洗液供给管路120可以布置在第一电极芯构件44ι和第二电极芯构件442之间。冲洗液供给管路120 A first rinsing liquid dispensing end of the second member 100j ^ 10 also may surround at least a portion of and / or around the first electrode core member 4 also, and the first rinsing liquid can also dispensing element 10 (h and the electrode 4 and the core member flushing port 106 defined between the annular ring :. flush port 1061 is configured toward the electrode housing 46 '' to guide the rinsing liquid, and thus the flushing fluid distally guide the second end of the first rinsing liquid distribution element of 1〇 1〇〇2 22 may engage at least a portion of the tip electrode 118. the various embodiments of the present invention, the tip electrode 118 may be flexible or not. 1〇42 least a portion of the second end of the second irrigation distribution element 100 may surround and 2 / surrounding the core member or the second electrode 442, and a second rinse liquid can also 1〇〇2 distribution member and defines an annular flush port 1062. annular flushing port 442 between the second electrode core member 1062 is configured to direct rinse liquid toward the electrode housing 46 ', and then guide the flushing fluid proximally. rinsing liquid supply line 120 may be disposed between the first electrode and the second electrode core member 44ι core member 442. rinsing liquid supply line 120 以与布置在导管轴杆18中的液体输送管22相同或可以与其液体连通。 In the liquid disposed in the catheter shaft 18 may be the same or delivery tube 22 in fluid communication therewith.
[0069]现参照图9,消融电极组件10' ''可以包括两个或更多个电极芯构件4也、442以及两个或更多个电极外壳46' 'ι、462。 [0069] Referring now to FIG 9, the ablation electrode assembly 10 '' 'may include two or more electrode core member 4 may, 442, and two or more housing electrodes 46' 'ι, 462. 虽然大致不出了两个电极芯构件44ι、442以及两个电极外壳46''^462,但根据本发明的各个实施方式，消融电极组件10'''可以包括任意数量的电极芯构件44和电极外壳46。 Although generally not the two electrode core member 44ι, 442 and the two electrodes of the housing 46 '' ^ 462, but according to various embodiments of the present invention, the ablation electrode assembly 10 '' 'may include any number of electrode core member 44 and electrode housing 46. 第一电极芯构件44ι可以布置在相对于第一电极外壳46' ' 1的近侧。 The first electrode may be disposed on the core member 44ι 'proximally relative to the first housing electrode 46' 1. 第一电极芯构件44ι可以与上面所述的电极芯构件44、44'基本相同。 44ι first electrode core member and the upper electrode may be of the core member 44, 44 'is substantially the same. 另外，第一电极外壳46'、可以与上面所述的电极外壳46基本相同。 Further, the first housing electrode 46 'may be of the housing 46 and the upper electrode is substantially the same. 第一电极外壳46'、可以是大致圆柱形，以及第一电极外壳46'、的第一和第二端78''、80''均可以是开口的。 A first housing electrode 46 'may be generally cylindrical, and a first electrode housing 46', the first and second ends 78 '', 80 '' may each be opened. 特别地，第一电极外壳46'、的第一端78' '可以被配置为连接至定位在第一电极外壳46'、的远侧的第二电极芯构件442,以及电极外壳46'、的第二端80' '可以被配置为连接至定位在第一电极外壳46'、的近侧的第一电极芯构件44ι。 In particular, the first electrode housing 46 ', a first end 78' 'may be configured to connect to a first electrode positioned in the housing 46', the distal core member 442 a second electrode, and an electrode housing 46 ', the the second end 80 '' may be configured to connect to a first electrode positioned in the housing 46 ', a first electrode of the proximal core member 44ι.
[0070] 第二电极芯构件442可以布置在相对于第二电极外壳462的近侧。 [0070] The second electrode core member 442 may be disposed proximally with respect to the housing 462 of the second electrode. 第二电极芯构件44 2可以与上面所述的电极芯构件44、44'基本相同。 The second electrode 442 may be a core member of the core member and the upper electrode 44, 44 'is substantially the same. 第二电极外壳462可以是大致圆柱形。 The second electrode 462 may be substantially cylindrical housing. 第二电极外壳46 2的第一端78可以是闭合的且可以是半球形和/或球形形状的。 A second electrode of a first end of the housing 78462 may be closed and may be hemispherical and / or spherical shape. 在第二电极外壳462布置在消融电极组件10' ''的远尖端时，第二电极外壳462的第一端78可以是半球形和/或球形的。 The second electrode 462 is disposed in the housing assembly when the ablation electrode 10 'distal tip' of a first shell end 78 of the second electrode 462 may be hemispherical and / or spherical. 然而，第二电极外壳462并非必须布置在消融电极组件的远尖端。 However, the second electrode 462 is not necessarily disposed in the housing distal tip of the ablation electrode assembly. 因此，在本发明的其他实施方式中，第二电极外壳46 2可以布置在沿消融导管16的任意位置。 Thus, in other embodiments of the present invention, the second electrode 462 may be arranged in the housing along the ablation catheter 16 in any position. 根据第二电极外壳462的位置，第二电极外壳462的第一端78可以是开口的或闭合的。 The position of the second electrode housing 462, a first shell end 78 of the second electrode 462 may be open or closed. 第二电极外壳46 2的第二端80可以是开口的，并且可以被配置为连接至第二电极芯构件442。 A second electrode of a second end of the housing 80462 may be open, and may be configured to be connected to the second electrode 442 of the core member.
[0071] 在一些实施方式中，图9中所大致示出的消融电极组件10'''可以包括两个或更多个冲洗液分配元件1〇〇ι、1〇〇2。 Ablation electrode assembly [0071] In some embodiments, in FIG. 9 shows a substantially 10 '' 'may include two or more flushing fluid distribution element 1〇〇ι, 1〇〇2. 冲洗液分配元件10(h、100 2可以与上面所述的冲洗液分配元件100基本相同。每个冲洗液分配元件100^1002的第二端104^1042的至少一部分可以围绕和/或环绕各自对应的电极芯构件44!、442,以及还可以在冲洗液分配元件100^1002和电极芯构件4如、44 2之间限定环形冲洗端口106^1062。每个环形冲洗端口106^1062被配置为引导冲洗液朝向电极外壳46' 'ι、462,以及因此每个冲洗液分配兀件ΙΟΟι、10〇2向远侧引导冲洗液。冲洗液供给管路120可以布置在第一电极芯构件4和和第二电极芯构件44 2之间。冲洗液供给管路120可以与布置在导管轴杆18中的液体输送管22液体连通。根据本发明的各个实施方式(并如图8-9所大致示出的），消融电极组件可以包括一连串的两个或更多个活动消融电极，其中每个消融电极具有其自己的非独立的（例如，共用源)或独立的（例如，离散源）的冲洗液 Rinse liquid distribution element 10 (h, 100 2 and 100 may be substantially the same as the flushing fluid dispensing member above at least a portion of each of the 1042 ^ rinse liquid dispensing end of the second member 100 may be about 104 ^ 1002 and / or around the respective corresponding electrode core member 44!, 442, and also may be rinsed distribution element 100 ^ 1002 and the electrode 4 as a core member, the second ring 44 defined between the flush port 106 ^ 1062 ^ each annular flushing port 106 are arranged in 1062 to direct rinse liquid toward the electrode housing 46 '' ι, 462, and thus each of the processing liquid distribution member Wu ΙΟΟι, 10〇2 direct irrigant distally rinsing liquid supply line 120 may be disposed on the first electrode core member 4 and between the core member and the second electrode 442. rinsing liquid supply line 120 may be in communication with the liquid in the liquid delivery tube 22 is disposed in the catheter shaft 18 in accordance with various embodiments of the present invention (FIG. 8-9, and substantially shown), an ablation electrode assembly may include a series of two or more active ablation electrode, wherein (e.g., a common source of each of the ablation electrode has its own non-independent) or independent (e.g., discrete source) washing liquid 配配置。 With the configuration.
[0072]虽然上面以一定程度的特殊性描述了本发明的至少四个实施方式，但本领域技术人员可以在不偏离本发明的精神或范围的情况下对本发明的实施方式做出多种改变。 [0072] While the above with a certain degree of particularity least four described embodiments of the invention, those skilled in the art that various changes may be made to the embodiments of the present invention without departing from the spirit or scope of the invention . 所有的方向参考(例如，上、下、向上、向下、左、右、向左、向右、高、低、上面、下面、垂直、7K平、顺时针、以及逆时针)仅用于标识目的以帮助阅读者理解本发明，且特别是对本发明的位置、 方向、或用途不产生限制。 All directional references (e.g., upper, lower, upward, downward, left, right, left, right, higher, lower, above, below, vertical, flat. 7K, clockwise, and counterclockwise) are only used to identify purposes to aid the reader in understanding the present invention, and in particular the present invention the position, direction, or the use of no limitation. 连接参考(例如，附接、耦合和连接等)应该被广义地解释并且可以包括元件的连接之间的中间构件和元件之间的相对移动。 Connection references (e.g., attached, coupled and connected, etc.) should be broadly construed and may include a relative movement between the intermediate member and the connecting element between the elements. 这样，连接参考并非必然直接指的是彼此直接地连接并处于固定关系的两种元件。 As such, connection references do not necessarily refer to a direct connection to one another directly and in fixed relation to two kinds of elements. 目的是上面描述中所包含的或附图中所示出的所有事物应该解释为说明性的而非限制性的。 All things purpose is shown to be interpreted as illustrative and not restrictive contained in the above description or accompanying drawings. 可以在不偏离所附权利要求书所限定的本发明的精神的情况下做出细节或结构的改变。 Changes in detail or structure may be made in the spirit of the present invention without departing from the appended claims as defined.
1. 一种具有纵向轴的消融电极组件，该组件包括： 电极芯构件，其包括具有降低的热传导性的绝热体，所述电极芯构件具有： Λ-Λ- 上山弟-栖； 第二端；以及至少一个冲洗通道； 电极外壳，其包括导电材料，所述电极外壳限定内部容积，以及所述电极外壳具有： 第一端；以及第二端，其中所述电极外壳的第二端被配置为连接至所述电极芯构件的第一端，以及其中所述电极外壳足够柔韧以相对于所述消融电极组件的纵向轴偏转所述电极外壳的远端； 冲洗液分配元件，其围绕所述电极芯构件的至少一部分，所述冲洗液分配元件具有： 第一端；以及第二端，其中所述冲洗液分配元件的第二端在所述冲洗液分配元件和所述电极芯构件之间限定环形冲洗端口， 其中所述电极芯构件还包括： 外表面；以及限定空腔的内表面，其中所述至少一个冲洗通道从 An ablation electrode assembly having a longitudinal axis, the assembly comprising: an electrode core member comprising a thermally conductive insulation reduction of the electrode core member having: Λ-Λ- uphill Di - habitat; second end ; and at least one flushing channel; an electrode housing comprising a conductive material, the housing defining an internal volume of the electrode, and the electrode housing having: a first end; and a second end, wherein a second end of said electrode housing is arranged a first end connected to the electrode core member, wherein the electrode case and sufficiently flexible to deflect the distal end of the electrode with respect to the longitudinal axis of the housing assembly of the ablation electrode; rinsing liquid distribution element surrounding the at least a portion of the electrode core member, said rinsing liquid distribution element having: a first end; and a second end, wherein said flushing fluid between the dispensing member in said second end and said rinse liquid dispensing element electrode core member defining an annular flush port, wherein the electrode core member further comprises: an outer surface; and an inner surface defining a cavity, wherein the at least one flushing channel from 部空腔延伸至所述电极芯构件的外表面。 A cavity portion extending to an outer surface of the electrode core member.
2. 根据权利要求1所述的消融电极组件，其中所述电极芯构件还包括轴向延伸通道，所述轴向延伸通道从所述电极芯构件的内部空腔延伸至所述电极外壳的第一端。 2. The first axially extending passageway extending from the interior cavity of the electrode to the electrode core member with an ablation electrode housing assembly of claim 1, wherein said electrode core member further includes an axially extending channel, said claims end.
3. 根据权利要求2所述的消融电极组件，还包括至少一个端口，所述端口从所述轴向延伸通道延伸至所述电极外壳的第一端，其中所述端口定向为相对于所述消融电极组件的纵向轴成锐角。 The ablation electrode assembly according to claim 2, further comprising at least one port extending from a first end of said axial passage extending to the electrode housing said port, wherein said port is oriented with respect to the the longitudinal axis of the ablation electrode assembly at an acute angle.
4. 根据权利要求2所述的消融电极组件，其中所述轴向延伸通道的外围的至少一部分和长度的至少一部分包括非导电材料的涂层。 4. The ablation electrode assembly according to claim 2, wherein at least a portion of at least a portion of the peripheral length of the axially extending passage comprises a non-conductive material coating.
5. 根据权利要求1所述的消融电极组件，其中所述电极外壳的至少一部分包括第一组凸起，所述第一组凸起至少部分限定对应的第一组凹槽，以及其中所述电极外壳的至少一部分包括第二组凸起，所述第二组凸起至少部分限定对应的第二组凹槽，其中所述第一组凸起中的至少一个被配置为与所述第二组凹槽中的至少一个互锁，以及其中所述第二组凸起中的至少一个被配置为与所述第一组凹槽中的至少一个互锁。 The ablation electrode assembly according to claim 1, wherein at least a portion of the electrode housing comprises a first set of protrusions, said first set of protrusions at least partially define a first set of grooves corresponding to, and wherein said at least a part of the electrode housing comprises a second projection set, the second set of protrusions at least partially define a second set of grooves corresponding to at least one of said second and configured wherein the first set of protrusions at least one set of interlocking grooves, and wherein said second set of at least one protrusion is configured to at least one of said first set of interlocking with the grooves.
6. 根据权利要求5所述的消融电极组件，其中所述第一组凸起中的每一个与所述第二组凸起中的每一个是梯形形状。 6. ablation electrode assembly according to claim 5, wherein said first set of projections in each of the second set of protrusions are each a trapezoidal shape.
7. 根据权利要求5所述的消融电极组件，其中所述第一组凸起中的每一个与所述第二组凸起中的每一个是圆形形状。 7. ablation electrode assembly according to claim 5, wherein said first set of projections in each of the second set of projections each of which is a circular shape.
8. 根据权利要求1所述的消融电极组件，其中所述电极外壳包括编织的金属线。 8. The ablation electrode assembly according to claim 1, wherein said housing includes a wire electrode is braided.
9. 根据权利要求1所述的消融电极组件，其中所述电极外壳包括缠绕的金属线。 9. The ablation electrode assembly of claim 1, wherein said housing includes a wire electrode is wound.
10. 根据权利要求1所述的消融电极组件，其中所述电极外壳包括聚合物。 10. The ablation electrode assembly according to claim 1, wherein said housing comprises a polymer electrode.
11. 根据权利要求10所述的消融电极组件，其中所述电极外壳包括硅酮材料。 11. The ablation electrode assembly of claim 10, wherein said electrode housing comprises a silicone material.
12. 根据权利要求10所述的消融电极组件，其中所述聚合物具有以预定密度分布于其中以实现期望的导电性的导电颗粒。 12. The ablation electrode assembly according to claim 10, wherein said conductive polymer has conductive particles in a predetermined density distribution therein to achieve desired.
13. 根据权利要求12所述的消融电极组件，其中所述颗粒包括金、银、铂、铱、钛、钨、或其组合。 13. The ablation electrode assembly according to claim 12, wherein said particles comprise gold, silver, platinum, iridium, titanium, tungsten, or combinations thereof.
14. 根据权利要求1所述的消融电极组件，还包括布置在由所述电极外壳限定的内部容积中的堵塞物。 14. The ablation electrode assembly according to claim 1, further comprising a plug disposed in the interior volume defined by the electrode in the housing.
15. 根据权利要求14所述的消融电极组件，其中所述堵塞物包括聚合物。 15. The ablation electrode assembly according to claim 14, wherein said plug comprises a polymer.
16. 根据权利要求15所述的消融电极组件，其中所述堵塞物包括硅酮材料。 16. The ablation electrode assembly according to claim 15, wherein said plug comprises a silicone material.
17. 根据权利要求15所述的消融电极组件，其中所述堵塞物具有预定的硬度以实现期望的柔性。 17. The ablation electrode assembly according to claim 15, wherein said plug has a predetermined stiffness to achieve the desired flexibility.
18. 根据权利要求1所述的消融电极组件，其中所述冲洗液分配元件包括圈环。 18. The ablation electrode assembly according to claim 1, wherein said flushing fluid comprises a dispensing member rings.
19. 根据权利要求1所述的消融电极组件，其中所述冲洗液分配元件还包括液体成形构件，其中所述液体成形构件包括通道、隆起、斜面、或其组合中的至少一个。 19. The ablation electrode assembly according to claim 1, wherein the rinse solution further comprises liquid dispensing element forming member, wherein said liquid includes a channel shaped member, ridges, ramp, or a combination of at least one.
20. -种用于心脏组织消融的系统，该系统包括： 导管，其包括： 导管轴杆，其具有液体管腔；以及电极组件，其连接至所述导管轴杆，所述电极组件包括： 电极芯构件，其包括具有降低的热传导性的绝热体，所述电极芯构件具有： Λ-Λ- 上山弟-栖； 第二端；以及至少一个冲洗通道； 电极外壳，其包括导电材料，所述电极外壳限定内部容积，以及所述电极外壳具有： 第一端；以及第二端，其中所述电极外壳的第二端被配置为连接至所述电极芯构件的第一端，以及其中所述电极外壳足够柔韧以相对于所述电极组件的纵向轴偏转所述电极外壳的远端； 冲洗液分配元件，其围绕所述电极芯构件，所述冲洗液分配元件具有： 第一端；以及第二端，其中所述冲洗液分配元件的第二端在所述冲洗液分配元件和所述电极芯构件之间限定环形冲洗端口； 布置在 20. - kind of a system for cardiac tissue ablation, the system comprising: a catheter comprising: a catheter shaft having a lumen liquid; and an electrode assembly, which is connected to the catheter shaft, the electrode assembly comprising: electrode core member, which comprises a thermal insulator having a reduced thermal conductivity, the electrode core member having: Λ-Λ- uphill Di - habitat; a second end; and at least one flushing channel; a conductive electrode material housing, which comprises the a housing defining an interior volume of said electrode, and said electrode housing having: a first end; and a second end, wherein a second end of said electrode housing is configured to be connected to a first end of the electrode core member, and wherein said electrode housing is sufficiently flexible to deflect the distal end of the electrode with respect to the longitudinal axis of said housing the electrode assembly; rinsing liquid distribution member surrounding the electrode core member, said flushing fluid dispensing member having: a first end; and a second end, wherein the flush port is defined between an annular dispensing said flushing fluid element in a second end of said flushing fluid dispensing element and said electrode core member; disposed 述导管中的至少一个热传感器； 消融发生器，其电连接到所述电极组件的至少一部分； 电子控制单元(ECU)，其能操作地连接至所述至少一个热传感器，其中所述ECU被配置为从多个热传感器中的所述至少一个接收输入数据，并被配置为至少部分地基于所述输入数据来控制至所述电极组件的能量输送和冲洗液输送。 Said at least one thermal sensor conduit; an ablation generator, electrically connected to at least a portion of the electrode assembly; an electronic control unit (ECU), which can be operatively connected to the at least one thermal sensor, wherein the ECU is configured from a plurality of thermal sensors to the at least one received input data, and configured to delivery and the delivery of flushing fluid is controlled at least in part to the electrode assembly energy based on the input data.
21. -种具有纵向轴的消融电极组件，该组件包括： 第一电极芯构件，其包括具有降低的热传导性的绝热体，所述第一电极芯构件具有： Λ-Λ- 上山弟-栖； 第二端；以及至少一个冲洗通道； 第二电极芯构件，其包括具有降低的热传导性的绝热体，所述第二电极芯构件具有： Λ-Λ- 上山弟-栖； 第二端；以及至少一个冲洗通道；以及第一电极外壳，其包括导电材料，所述第一电极外壳限定内部容积以及所述第一电极外壳具有： 第一端，其被配置为连接至所述第一电极芯构件的第一端；以及第二端，其被配置为连接至所述第二电极芯构件的第一端，其中所述电极外壳足够柔韧以相对于所述消融电极组件的纵向轴偏转所述电极外壳。 21. - Species ablation electrode assembly having a longitudinal axis, the assembly comprising: a first electrode core member comprising a thermally conductive insulating body reduced, the first electrode core member having: Λ-Λ- mountain brother - habitat ; a second end; and at least one flushing channel; and a second electrode core member comprising a thermally conductive insulating body lowered, the second electrode core member having: Λ-Λ- uphill Di - habitat; a second end; and at least one flushing channel; a first electrode and a housing which includes a conductive material, the housing defining an interior volume of the first electrode and the first electrode housing having: a first end configured to connect to the first electrode a first end of the core member; and a second end, which is configured as a first end connected to the second electrode core member, wherein the electrode is flexible enough to the longitudinal axis of the housing of the deflection with respect to the ablation electrode assembly said electrode housing.
22. 根据权利要求21所述的消融电极组件，还包括： 第一冲洗液分配元件，其围绕所述第一电极芯构件的至少一部分，所述第一冲洗液分配元件具有： 第一端；以及第二端，其中，所述第一冲洗液分配元件的第二端在所述第一冲洗液分配元件和所述第一电极芯构件之间限定第一环形冲洗端口；以及第二冲洗液分配元件，其围绕所述第二电极芯构件的至少一部分，所述第二冲洗液分配元件具有： 第一端；以及第二端，其中，所述第二冲洗液分配元件的第二端在所述第二冲洗液分配元件和所述第二电极芯构件之间限定第二环形冲洗端口。 22. The ablation electrode assembly according to claim 21, further comprising: a first rinsing liquid dispensing element, the first electrode surrounding at least a portion of the core member, the first rinsing liquid distribution element comprising: a first end; and a second end, wherein the second end of the first rinsing liquid distribution element between the first rinsing liquid distribution element and the first electrode core member defining a first annular irrigation port; and a second rinsing liquid dispensing element, said second electrode surrounding at least a portion of the core member, said second member having a dispensing flushing fluid: a first end; and a second end, wherein the second end of the second rinse liquid distribution element in the second flushing liquid distribution between the flush port defining a second annular element and the second electrode core member.
23. 根据权利要求21所述的消融电极组件，还包括第二电极外壳，所述第二电极外壳包括导电材料，所述第二电极外壳限定内部容积并具有被配置为连接至所述第二电极芯构件的第一端。 23. The ablation electrode assembly of claim 21, further comprising a second housing electrode, the second electrode material comprises a conductive housing, said second electrode having a housing defining an interior volume and configured to be connected to the second claim a first end of the electrode core member.
CN201280003945.8A 2010-12-17 2012-02-27 Flushing fluid dispensing system for a flexible electrode, CN103237515B (en)
US13/1624,17 2011-06-16
CN103237515A CN103237515A (en) 2013-08-07
CN103237515B true CN103237515B (en) 2016-11-02
CN201280003945.8A CN103237515B (en) 2010-12-17 2012-02-27 Flushing fluid dispensing system for a flexible electrode,
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