Source: http://www.google.com/patents/US20050080454?dq=6,455,937
Timestamp: 2017-01-16 18:04:02
Document Index: 720192297

Matched Legal Cases: ['art 110', 'art 112', 'art 110', 'art 110', 'art 112', 'art 110', 'art 112', 'art 110', 'art 112']

Patent US20050080454 - Attachment device and methods of using the same - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsDevices for attaching a first mass and a second mass and methods of making and using the same are disclosed. The devices can be made from an resilient, elastic or deformable materials. The devices can be used to attach a heart valve ring to a biological annulus. The devices can also be used for wound...http://www.google.com/patents/US20050080454?utm_source=gb-gplus-sharePatent US20050080454 - Attachment device and methods of using the sameAdvanced Patent SearchTry the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents.Publication numberUS20050080454 A1Publication typeApplicationApplication numberUS 10/681,700Publication dateApr 14, 2005Filing dateOct 8, 2003Priority dateOct 8, 2003Also published asCA2541171A1, CA2541171C, DE602004024696D1, EP1670364A2, EP1670364B1, EP2196159A1, US7556647, US8603161, US20100010616, US20140100652, WO2005041784A2, WO2005041784A3Publication number10681700, 681700, US 2005/0080454 A1, US 2005/080454 A1, US 20050080454 A1, US 20050080454A1, US 2005080454 A1, US 2005080454A1, US-A1-20050080454, US-A1-2005080454, US2005/0080454A1, US2005/080454A1, US20050080454 A1, US20050080454A1, US2005080454 A1, US2005080454A1InventorsMichael Drews, Donnell Gurskis, Steven BacichOriginal AssigneeDrews Michael J., Gurskis Donnell W., Bacich Steven R.Export CitationBiBTeX, EndNote, RefManPatent Citations (63), Referenced by (452), Classifications (17), Legal Events (4) External Links: USPTO, USPTO Assignment, EspacenetAttachment device and methods of using the same
DETAILED DESCRIPTION [0044] FIGS. 1 through 3 illustrate an attachment device 2. The attachment device 2 can have a base 4, legs 6, and a tip 8 at the end of each leg 6. (Phantom lines delineate the base 4, legs 6 and tips 8.) The base 4, legs 6 and tips 8 can be separate or integral elements. A flag 10 can be attached to, and extend from, the base 4. The base 4 and/or the legs 6 can be straight or curved. [0045] The attachment device 2 can be made from a deformable or elastic material or a combination of materials having resulting deformable or elastic properties. The material can be, for example, stainless steel alloys, nickel titanium alloys (e.g., Nitinol), cobalt-chrome alloys (e.g., ELGILOY® from Elgin Specialty Metals, Elgin, Ill.; CONICHROME® from Carpenter Metals Corp., Wyomissing, Pa.), polymers such as polyester (e.g., DACRON® from E. I. Du Pont de Nemours and Company, Wilmington, Del.), polypropylene, polytetrafluoroethylene (PTFE), expanded PTFE (ePTFE), polyether ether ketone (PEEK), nylon, polyether-block co-polyamide polymers (e.g., PEBAX® from ATOFINA, Paris, France), aliphatic polyether polyurethanes (e.g., TECOFLEX® from Thermedics Polymer Products, Wilmington, Mass.), polyvinyl chloride (PVC), polyurethane, thermoplastic, fluorinated ethylene propylene (FEP), extruded collagen, silicone, echogenic, radioactive, radiopaque materials or combinations thereof. Examples of radiopaque materials are barium sulfate, titanium, stainless steel, nickel-titanium alloys, tantalum and gold. [0046] Any or all elements of the attachment device 2 can be a matrix for cell ingrowth or used with a fabric, for example a covering (not shown) that acts as a matrix for cell ingrowth. The fabric can be, for example, polyester (e.g., DACRON® from E. I. du Pont de Nemours and Company, Wilmington, Del.), polypropylene, PTFE, ePTFE, nylon, extruded collagen, silicone or combinations thereof. [0047] The attachment device 2 and/or the fabric can be filled and/or coated with an agent delivery matrix known to one having ordinary skill in the art and/or a therapeutic and/or diagnostic agent. These agents can include radioactive materials; radiopaque materials; cytogenic agents; cytotoxic agents; cytostatic agents; thrombogenic agents, for example polyurethane, cellulose acetate polymer mixed with bismuth trioxide, and ethylene vinyl alcohol; lubricious, hydrophilic materials; phosphor cholene; anti-inflammatory agents, for example non-steroidal anti-inflammatories (NSAIDs) such as cyclooxygenase-1 (COX-1) inhibitors (e.g., acetylsalicylic acid, for example ASPIRIN® from Bayer AG, Leverkusen, Germany; ibuprofen, for example ADVIL® from Wyeth, Collegeville, Pa.; indomethacin; mefenamic acid), COX-2 inhibitors (e.g., VIOXX® from Merck & Co., Inc., Whitehouse Station, NJ; CELEBREX® from Pharmacia Corp., Peapack, NJ; COX-1 inhibitors); immunosuppressive agents, for example Sirolimus (RAPAMUNE®, from Wyeth,, Collegeville, Pa.), or matrix metalloproteinase (MMP) inhibitors (e.g., tetracycline and tetracycline derivatives) that act early within the pathways of an inflammatory response. Examples of other agents are provided in Walton et al, Inhibition of Prostoglandin E2 Synthesis in Abdominal Aortic Aneurysms, Circulation, Jul. 6, 1999, 48-54; Tambiah et al, Provocation of Experimental Aortic Inflammation Mediators and Chlamydia Pneumoniae, Brit. J. Surgery 88 (7), 935-940; Franklin et al, Uptake of Tetracycline by Aortic Aneurysm Wall and Its Effect on Inflammation and Proteolysis, Brit. J. Surgery 86 (6), 771-775; Xu et al, Sp1 Increases Expression of Cyclooxygenase-2 in Hypoxic Vascular Endothelium, J. Biological Chemistry 275 (32) 24583-24589; and Pyo et al, Targeted Gene Disruption of Matrix Metalloproteinase-9 (Gelatinase B) Suppresses Development of Experimental Abdominal Aortic Aneurysms, J. Clinical Investigation 105 (11), 1641-1649 which are all incorporated by reference in their entireties. [0048] A base axis 12 can extend longitudinally through the transverse cross-sectional center of the base 4. As shown in FIG. 2, when viewed from the side, the base axis 12 can form a base plane angle 14 from about 0° to about 30°, for example about 10°. The base 4 can have a base inner radius 16 from about 0.25 mm (0.010 in.) to about 19.1 mm (0.750 in.), for example about 1.91 mm (0.075 in.). The proximal end of the base 4 can be formed into a table 17. The table 17 can be a flat surface that tapers to the base 4. [0049] The base 4 and legs 6 can have a shaft diameter 18 from about 0.03 mm (0.001 in.) to about 6.35 mm (0.250 in.), for example, about 0.51 mm (0.020 in.). The base 4 and legs 6 can have the same or different shaft diameters 18. A base neutral radius 19 can be the base inner radius 16 and half the shaft diameter 18. As shown in FIG. 1, the legs 6 can intersect at a leg angle 20 in or near the plane of the attachment device 2 or in or near the approximate plane of the base 4. An approximate plane is a plane that can be used whether the base 4 does or does not fall on a flat plane. If the base 4 is a straight line or a point, the approximate plane of the base 4 can be calculated using the points of the legs 6 that are nearest the base 4 and out of line with the base 4. The leg angle 20 can be from about 180° to about 10°, more narrowly from about 90° to about 60°, for example about 45° or, for example, about 60°. [0050] The length from an end of the base 4 to a longitudinal leg axis 24 can be a body length 22. The body length 22 can be from about 0.25 mm (0.010 in.) to about 12.7 mm (0.500 in.), for example about 2.913 mm (0.1147 in.). The length between the distal end of one tip 8 and the distal end of the opposite tip 8 can be a tip distance 26. The tip distance 26 can be from about 0.03 mm (0.001 in.) to about 25.4 mm (1.000 in.), more narrowly about 1.3 mm (0.050 in.) to about 3.18 mm (0.125 in.), for example about 2.3 mm (0.090 in.). [0051] The tip 8 can have a tip length 28 from about 0.05 mm (0.002 in.) to about 12.7 mm (0.500 in.), for example about 1.0 mm (0.040 in.). The tip 8 can have a tip angle 30 from about 50 to about 90°, for example about 30°. The tips 8 can be straight, pointed ends, curve out of line (shown by alternative tips 8 a and 8 b, drawn in phantom lines in FIGS. 2 and 3) from the nearest end of the leg 6, or combinations thereof. [0052] The tips 8 and/or legs 6 can have retention devices 29. The retention devices 29 can be barbs, spikes, hooks, threads, ribs, splines, a roughened surface, a sintered surface, a covered surface (e.g., with DACRON® from E. I. du Pont de Nemours and Company, Wilmington, Del.) or combinations thereof. A retention coating 31, for example a biodegradable coating or filler such as gel or gelatin or otherwise removable, can be on and/or around and/or near the retention devices 29. The retention coating 31 (shown in phantom lines) can be configured to render the retention device 29 substantially ineffective until a substantial amount of the retention coating 31 has been biodegraded or otherwise removed. [0053] The legs 6 can have mechanical interfaces 33, for example, a slot, snap, protrusion, latch, catch or combinations thereof. The interfaces 33 can be aligned so the interface on one leg 6 meets the interface 33 on the other leg 6 at the point where the legs 6 cross. The interfaces 33 can removably attach to each other. [0054] FIGS. 4 through 10 illustrate examples of cross-section A-A of the legs 6 and/or the base 4. The cross-section A-A of the legs 6 can be the same or different as the cross-sections of the base 4. The cross-sections of the base 4 and/or legs 6 can be constant or vary along their respective lengths. FIGS. 4 through 8, respectively, illustrate circular, rectangular (including square), triangular, substantially flat, and star-David shaped or irregular cross-sections A-A. FIG. 9 illustrates an oval cross-section A-A. A ratio of the shaft diameter 18 to the length of a minor axis 32 can be from about 1:1 to about 20:1, for example 10:1. [0055] FIG. 10 illustrates a cavity 36 inside the cross-section A-A. The cavity 34 can be hollow or can be filled completely or partially. The cavity 34 can be filled with an agent delivery matrix known to one having ordinary skill in the art and/or a therapeutic and/or diagnostic agent and/or echogenic and/or radioactive and/or radiopaque materials, for example, the agents and/or materials listed supra. The type and amount of filling can vary along the length of the base 4 and/or legs 6. The ratio of the shaft diameter 18 to a cavity diameter 36 can be from about 1:1 to about 50:1, for example, about 2:1. [0056] FIG. 11 illustrates an attachment device 2 that can have a leg 6 that can have a first leg segment 38 and a second leg segment 40. The first leg segment 38 can extends from the base 4. The second leg segment 40 can extend on a proximal end from the first leg segment 38. The tip 8 can extend from a distal end of the second leg segment 40. The second leg segment 40 can have a different radius of curvature than the first leg segment 38 and/or form an angle with respect to the first leg segment 40. FIG. 12 illustrates that the second leg segment 40 can form an angle (shown by arrows) with the approximate plane of the base 4. FIG. 13 illustrates that the first leg segment 38 can form an angle (shown by arrows) with the approximate plane of the base 4. The second leg segments 40 can be substantially parallel with the approximate plan of the base 4. [0057] FIG. 14 illustrates an attachment device 2 that can have a first leg 6 a that can be substantially longer than a second leg 6 b. The ratio of a first leg-tip length 22 a to a second leg-tip length 22 b can be from about 1:1 to about 10:1, for example, about 3:1. [0058] FIG. 15 illustrates an attachment device that can have a first leg radius 42 and a second leg radius 44. The ratio of the first leg radius 42 to the second leg radius 44 can be from about 1:1 to about 50:1, for example about 10:1. [0059] FIGS. 16 and 17 illustrate an attachment device 2 that can have a “flat top.” The approximate plane of the second leg 6 b can form an angle, for example about 90°, with the approximate plane of the base 4. When in use, the flat top can further anchor the attachment device 2 against the first mass and/or second mass. FIGS. 18 and 19 illustrate an attachment device 2 that can have arms 6 that can wrap around the base axis 12. [0060] FIG. 20 illustrates an attachment device 2 that can have arms 46 that can extend from the base 4 and/or the legs 6. When deployed, the arms 46 can squeeze tissue between the arms 46 and the legs 6 and/or base 4 for additional retention force. Anchors 48 can extend from the arms 46, for example at the distal ends of the arms 46. The anchors 48 can be, for example, hooks, barbs, spikes, staples or combinations thereof. The anchors 48 can extend directly from the base 4 and/or legs 6 with or without arms 46 separately attached to the base 4 and/or legs 6. FIG. 21 illustrates an attachment device 2 that can have a straight base 4 and can have the arms 46 extending from the base 4. [0061] FIGS. 22 and 23 illustrate an attachment device that can have first, second and third legs 6 a, 6 b and 6 c. The base 4 can be a platform, wireframe, or point attachment which can be spot-welded or brazed, tube crimped or otherwise mechanically connected. The planes of the legs 6 a, 6 b and 6 c can intersect at substantially equal angles, about 120°, or unequal angles. [0062] FIG. 24 illustrates an attachment device that can have a first loop 49 and a second loop 51. The first loop 49 can be formed from the base 4 and a proximal portion of the first leg segments 38. The second loop 51 can be formed from a distal portion of the first leg segments 38 and a proximal portion of the second leg segments 40. [heading-0063] Methods of Making [0064] FIG. 25 illustrates a mandrel 50 that can be used to form the attachment device 2, for example during heat treatment. The base 4 and/or legs 6 can be held on the mandrel 50 by a single cylinder 52, a formed path 54, a pressure plate 56, for example a washer under a screw or combinations thereof. Methods for forming shape memory alloys (e.g., Nitinol) are known to those having ordinary skill in the art. The tips 8 can be formed, for example, by grinding, electropolishing, or precision sharpening (e.g., polishing services from Point Technologies, Inc., Boulder, Colo.) to a satisfactory geometry, including a trocar point, beveled, rounded, tapered, pointed or flattened. [0065] Other methods known to one having ordinary skill in the art can be used to manufacture the attachment device 2 and/or its elements. For example, manufacturing techniques include molding, machining, casting, forming (e.g., pressure forming), crimping, stamping, melting, screwing, gluing, welding, die cutting, laser cutting, electrical discharge machining (EDM), etching or combinations thereof. [0066] Any elements, sub-assemblies, or the attachment device 2 as a whole after final assembly, can be coated by dip-coating or spray-coating methods known to one having ordinary skill in the art, utilizing materials such as PTFE (e.g., TEFLON® from E. I. du Pont de Nemours and Company, Wilmington, Del.), polyester (e.g., DACRON® from E. I. du Pont de Nemours and Company, Wilmington, Del.), gelatin, gel, other polymers or combinations thereof. One example of a method used to coat a medical device for vascular use is provided in U.S. Pat. No. 6,358,556 by Ding et al. and hereby incorporated by reference in its entirety. Time release coating methods known to one having ordinary skill in the art can also be used to delay the release of an agent in the coating. The coatings can be thrombogenic or anti-thrombogenic. [0067] The attachment device 2, or any element thereof (e.g., the base 4) can be covered with a fabric, for example polyester (e.g., DACRON® from E. I. du Pont de Nemours and Company, Wilmington, Del.), polypropylene, PTFE (e.g., TEFLON® from E. I. du Pont de Nemours and Company, Wilmington, Del.), ePTFE, nylon, extruded collagen, gel, gelatin, silicone or combinations thereof. Methods of covering an implantable device with fabric are known to those having ordinary skill in the art, for example, sintering, spray coating, adhesion, loose covering, dipping or combinations thereof. [heading-0068] Methods of Using [0069] The attachment device 2 can have a first configuration (e.g., the configuration shown in FIGS. 26 and 27) and a second configuration (e.g., the configuration shown in FIGS. 1 through 3). The attachment device 2 can have the second configuration when the attachment device is in a relaxed state, with no external forces applied (e.g., prior to insertion or use). The attachment device 2 can have the first configuration when external forces are applied, such as by a delivery tool prior to delivery. When external forces are removed from the attachment device 2, the attachment device 2 can revert from the first configuration to the second configuration. [0070] The attachment device can substantially revert to the second configuration even when some permanent hysteresis deformation occurs and/or when a foreign object (e.g., a first and/or second mass) is obstructing the attachment device 2. When the attachment device 2 has the first configuration, one or both legs 6 can be rotated with respect to the base 4 (e.g., by rotating the base 4 around the base axis 12, one or both legs 6 splay or separate as they are torqued by the twisting or rotating around of the base). [0071] FIG. 26 illustrates a method of forcing the attachment device to have the first configuration. The attachment device 2 can be forced to have the first configuration by the application of a base torque, shown by arrows 58, applied about the base axis 12. The base torque can be directly applied to the base 4. The base torque indirectly becomes, or can be applied as, a leg torque, as shown by arrows 60 a and 60 b, to the legs 6 a and/or 6 b about the leg axes 24 a and 24 b. If approximately two times the base neutral radius 19 is less than the tip distance 26, the legs 6 will splay outward when entering the first mass 68. If approximatelt two times the base neutral radius 19 is greater than or equal to the tip distance 26, the legs 6 will splay inward or stay vertical when deploying into the first mass 68. [0072] FIG. 27 illustrates a method of forcing the attachment device to have the first configuration. The attachment device 2 can be forced to have the first configuration by the application of a pivot torque, shown by arrows 62, applied about the area where the base 4 attaches to the legs 6, so that the legs 6 are forced to pivot radially outward from each other. The pivot torque can be applied by applying outward translational forces, as shown by arrows 64, to one or both legs 6. The pivot torque can be applied by applying translational forces to the base 4, as shown by arrows 66. [0073] As illustrated in FIGS. 28 through 30, the attachment device 2 can be deployed to attach a first mass 68 to a second mass 70. The first mass 68 and/or the second mass 70 can be a prosthesis and/or a tissue, or both tissue or both prostheses. The prosthesis can be, for example, cardiac leads, markers, stents, grafts, stent-grafts, heart valves, annuloplasty rings, autografts, allografts, xenografts or any assemblies thereof or combination thereof. The tissue can be, for example, vessels, valves, organs (e.g., intestine, heart, skin, liver, kidney, urethra, bone mass, tendon, nerve, muscle), calcified soft tissue or any combination thereof. [0074] Heart valve assemblies disclosed by Griffin et al. in U.S. Pat. No. 6,241,765, by Lane in U.S. Pat. No. 6,371,983 and by Ritz in U.S. Pat. No. 5,976,183, both of which are hereby incorporated in their entireties, can be placed with the use of the device of the present invention. Other heart valve assemblies that can be used include, for example, the Advantage Bileaflet heart valve, Parallel valve, Freestyle stentless aortic valve, Hancock Porcine heart valve, Hancock apical left ventricular connector model 174A, Hancock valved conduit models 100, 105, 150, Hall Medtronic heart valve, Hall Medtronic valved conduit, MOSAIC® heart valve and Intact porcine tissue valve (by Medtronic, Inc. Minneapolis, Minn.); Angelini Lamina-flo valve (by Cardio Carbon Company, Ltd., England); Bjork-Shiley single-disk, monostrut and caged-disk valves (Shiley, Inc., now-defunct, previously of CA); Wada-Cutter valve and Chitra Cooley-Cutter valve (by Cutter Biomedical Corp., San Diego, Calif.); Angioflex trileaflet polyurethane valve (by Abiomed, Inc., Danvers, MA); ATS AP Series heart valve and ATS Standard heart valve (by ATS Medical, Inc., Minneapolis, Minn.); ANNULOFLO® annuloplasty ring, ANNUFLEX® annuloplasty ring, CARBSEAL® valved conduit, ORBIS® Universal aortic and mitral valve, pediatric/small adult valve, R series valve, SUMIT® mitral valve, TOP HAT® aortic valve, OPTIFORM® mitral valve, MITROFLOW SYNERGY® PC stented aortic pericardial bioprosthesis and the SYNERGY® ST stented aortic and mitral porcine bioprosthesis (by CarboMedics, Inc., Austin, Tex.); ON-X® prosthetic heart valve (by MCRI®, LLC, Austin, Tex.); Starr-Edwards SILASTIC® ball valve, Starr-Edwards 1000, Starr-Edwards 1200, Starr-Edwards 1260, Starr-Edwards 2400, Starr-Edwards 6300, Starr-Edwards 6500, Starr-Edwards 6520, Carpentier-Edwards porcine tissue valve, Carpentier-Edwards pericardial prosthesis, Carpentier-Edwards supra-annular valve, Carpentier-Edwards annuloplasty rings, Duromedics valve and PERIMOUNT® heart valve (by Edwards Lifesciences Corp., Irvine, Calif.); Cross-Jones Lenticular disc valve (by Pemco, Inc.); Tissuemed stented porcine valve (by Tissuemed, Ltd., Leeds, England); Tekna valve (by Baxter Healthcare, Corp., Deerfield, Ill.); Komp-01 mitral retainer ring (by Jyros Medical Ltd., London, England); SJM® Masters Series mechanical heart valve, SJM® Masters Series aortic valved graft prosthesis, ST. JUDE MEDICAL® mechanical heart valves, ST. JUDE MEDICAL® mechanical heart valve Hemodynamic Plus (HP) series, SJM REGENT® valve, TORONTO SPV® (Stentless Porcine Valve) valve, SJM BIOCOR® valve and SJM EPIC® valve (St. Jude Medical, Inc., St. Paul, Minn.); Sorin Bicarbon, Sorin Carbocast, Sorin Carboseal Conduit, Sorin Pericarbon and Sorin Pericarbon Stentless (by Snia S.p.A., Italy). The attachment devices of the present invention may be deployed to implant these various devices in the supra-annular position, or infrannular, depending on the geometry and preferred placement of a particular device. Similarly, it may be advantageous to use the attachment devices 2 of the present invention to secure a sewing ring, or first prosthesis by placing them horizontally or vertically within or around the annulus of such ring, prior to placing a second prosthesis including a valve structure, as provided in U.S. application Ser. No. 10/646,639 filed, 22 Aug. 2003, hereby incorporated by reference in its entirety. [0075] FIG. 28 illustrates that the attachment device 2 can be held in the first configuration. The attachment device 2 can be fed through a pledget 71 before the attachment device 2 is forced into the first mass 68. The pledget 71 can be a piece of fabric, for example, a fabric listed supra. The pledget 71 can be loaded onto the attachment device 2 before use. FIG. 29 illustrates that the attachment device 2 can be forced, as shown by arrow 72, into and through the first mass 68 and part of the second mass 70. FIG. 30 illustrates that the attachment device 2 can be released from having the first configuration. The attachment device 2 can revert to having substantially the second configuration. A pinching force, shown by arrows, can be applied to the attachment device 2 to encourage additional reversion of the attachment device 2 to having the second configuration. The attachment device 2 shown in FIG. 24 can be deployed in the same manner as described supra, except that the attachment device 2 shown in FIG. 24 can be rotated sufficiently to straighten the first and second loops, before or during deployment. [0076] The attachment device 2 can be removed and redeployed at any stage of deployment supra, for example, if the surgeon is unsatisfied with the position of the attachment device 2, or if the prosthesis need replacing or “redoing” at a point in the future. If the attachment device 2 has a retention device 29, when the retention coating 31 sufficiently biodegrades or is otherwise removed, the retention devices 29 will become exposed and can substantially prevent the removal of the attachment device 2 from the deployment site. Removal may still be achieved however, by apply sufficient force (by a tool or other device) to overcome the strength of the secdondary retention element. [0077] FIGS. 31 though 33 illustrate a method of deploying the attachment device 2 to attach a first mass 68 to a second mass 70. The pledget 71 can be fed over the attachment device 2 before use. The pledget 2 can be formed as a rectangular container with an access opening 73, for example a slit, hole, or aperture, to allow access to the base 4 of the attachment device 2. The attachment device 2 can have the second configuration. The attachment device 2 can be forced, as shown by arrow, so the tips 8 engage the first mass 68. FIG. 32 illustrates that, with the tips 8 held by the first mass 68, a longitudinal torque, shown by arrows, applied to the attachment device 2 about a longitudinal axis 74 can then force the attachment device 2 into the first configuration. As illustrated by FIG. 33, the attachment device 2 can be forced, shown by arrow, through the first mass 68 and part of the second mass 70. The longitudinal torque (not shown in FIG. 33) can be removed during deployment or after the attachment device 2 is completely deployed into the first and second masses 68 and 70. The pledget 71 can be crushed during deployment. [0078] FIGS. 34 through 36 illustrate a method of deploying the attachment device shown in FIG. 14. The first leg 6 a can be forced, as shown by arrow, into and through the first mass 68 and part of the second mass 70. The first leg 6 a can have a “paddle” (not shown). The paddle can be a flat oval or long rectangular cross-sectional shape on one leg. The paddle can increase resistive force with the first and/or second mass 68 and/or 70 when applying torque to the attachment device 2. [0079] FIG. 35 illustrates that the attachment device 2 can be forced into the first configuration by applying a base torque, shown by arrows 58. The second leg 6 b can then rotate outwardly from the attachment device 2, as shown by arrow 76. [0080] FIG. 36 illustrates that the attachment device 2 can be forced, shown by arrow, through the first mass 68 and part of the second mass 70. The base torque (not shown in FIG. 36) can be removed during deployment or after the attachment device 2 is completely deployed into the first and second masses 68 and 70. [0081] FIGS. 37 through 39 illustrate a method of deploying the attachment device 2 shown in FIGS. 18 and 19. FIG. 37 illustrates that the base 4 and the tips 8 can be placed in contact with or near the first mass 68. FIG. 38 illustrates that the arms 6 can be rotated, as shown by arrows, about the base axis 12. The arms 6 can be rotated to cause the arms 6 to be forced into the first mass 68. FIG. 39 illustrates that the arms 6 can be rotated, as shown by arrows, further about the base axis 12. The arms 6 can be forced into and through the second mass 70. The arms 6 can re-enter the first mass 68. [0082] FIGS. 40 through 42 illustrate a method of deploying the attachment device 2 to attach a first mass 68 to a second mass 70. The first mass 68 and the second mass 70 can be two sections of the same object, such as when the attachment device 2 is used to close a wound. FIG. 40 illustrates that the attachment device 2 can be held in the first configuration. FIG. 41 illustrates that the attachment device 2 can be forced, as shown by arrow 72, so that the first leg 6 a inserts into the first mass 68 and that the second leg 6 b inserts into the second mass 70. FIG. 42 illustrates that the attachment device 2 can be released from having the first configuration. The attachment device 2 can revert to having substantially the second configuration, causing the legs 6 a and 6 b to rotate inward, shown by arrows 78, applying force, shown by arrows 80, to the first mass 68 and the second mass 70 such that the first and second masses 68 and 70 move toward each other. [0083] The attachment device 2 can be removed from the second mass 70 and/or the first mass 68, when applicable, by reversing the steps of the deployment methods supra. [0084] FIG. 43 illustrates that, during use, the attachment device 2 can be covered by new tissue growth 82. The flag 10 can extend outside of the new tissue growth 82 (as shown) or be located just below the surface but palpable. The flag 10 can act as a marker, palpable or visible by direct vision or imaging modalities known in the art (e.g., x-ray, magnetic resonance imaging (MRI), ultrasound, computed tomagraphy (CT), echocardiogram) for example to locate the attachment device 2 in case of removal of the attachment device 2. The flag 10 can be made of, for example, suture material (e.g., Nylon, polyglycolic acid, polyester such as DACRON® from E. I. du Pont de Nemours and Company, Wilmington, Del., metals such as those used in the other elements of the attachment device 2, other polymers or combinations thereof). The base 4 can also serve this function (e.g., of a marker) in some applications. [0085] FIG. 44 illustrates a tool 84 for deploying the attachment device 2. The tool 84 can have a first lever 86 and a second lever 88. The first lever 86 can be rotatably attached to the second lever 88 at a pivot 90. The first and second levers 86 and 88 can have a handle 92 at each lever's first end and a pad 94 at each lever's second end. The pads 94 can be used to hold the attachment device 2. When a force is applied to the handles 92, shown by arrows 96, the force is transmitted, shown by arrows 98, to the pads 94. [0086] A driver shaft 100 can have a driver handle 102 at a first end and grips 104 at a second end. The pivot 90 can have a longitudinal channel 106. The driver shaft 100 can pass through the longitudinal channel 106 and/or be rotatably mounted to a case (not shown) fixed to a lever 86 or 88. The grips 104 can be releasably attached to the attachment device 2. The attachment device 2 can be rotated about the longitudinal axis 2 by releasing the pads 94 and rotating, as shown by arrows 108, the driver handle. [0087] FIG. 45 shows the end of a tool 84 for deploying the attachment device 2 before the attachment device 2 has been loaded into the tool 84. The tool 84 can have a top part 110 and a bottom part 112. The top part 110 can be removably attached to the bottom part, as shown by arrow 114. [0088] The top part 110 and/or the bottom part 112 can have grooves 116 sized to fit the base 4 and a portion of one or more legs 6 when the attachment device 2 has the first configuration. The attachment device 2 can be forced to have the first configuration and be loaded into the tool 84, as shown by arrow 118. The top part 110 can be attached to the bottom part 112 with the attachment device 2 seated (not shown) in the grooves 116. [0089] The attachment device 2 can be placed at a desired deployment site by the tool 84. The device 2 can be deployed from the tool 84 by removing the top part 110 from the bottom part 112, and removing the tool 84 from the deployment site. [0090] FIG. 46 illustrates an end of a tool 84. The tool 84 can have a case 120 with an anvil 122 and leg ports 124. The case 120 can be slidably attached to a slide 126. The attachment device 2 can be loaded around the anvil 122. The legs 6 can protrude from the case 120 through the leg ports 124. [0091] FIG. 47 illustrates a method of using the tool 84 of FIG. 46 to deploy the attachment device 2. The slide 126 can be forced, as shown by arrow 128, toward the anvil 122. The slide 126 can push the base 4 against the anvil 122, causing the legs 6 to rotate outward, as shown by arrows 76. The surface geometry of the anvil 122 and the slider 126 can match the surface geometry of the attachment device 2, when the attachment device is fully strained, as shown in FIG. 39. The attachment device 2 can then be inserted into the desired deployment site (not shown). When the attachment device 2 is in place, the attachment device 2 can be deployed from the tool 84, for example, by sliding the anvil 122 out of the way (perpendicular to the plane of FIG. 47) and forcing the attachment device 2 out the end of the tool 84 with the slide 126. [0092] The ends of the tools 84 shown in FIGS. 45 through 47 can be pivoted to the remainder of the tool 84 by methods known to those having ordinary skill in the art. The pivotable end of the tool 84 can improve access to deployment sites not as easily accessible by a non-articulating tool 84. The tool 84 can be non-articulatable. It would also be possible when access to the site of implantation allows, to employ a tool substantially similar to a needle driver tool known to those skilled in the art. [0093] Additional disclosure is included in U.S. patent application Ser. Nos. 10/327,821 and 10/646,639, filed 20 Dec. 2002 and 22 Aug. 2003, respectively, which are hereby incorporated by reference in their entireties. It is apparent to one skilled in the art that various changes and modifications can be made to this disclosure, and equivalents employed, without departing from the spirit and scope of the invention. Elements shown with any embodiment are exemplary for the specific embodiment and can be used on other embodiments within this disclosure. Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS464065 *Jul 21, 1891Dec 1, 1891 Steam-boilerUS3143742 *Mar 19, 1963Aug 11, 1964Surgitool IncProsthetic sutureless heart valveUS3371352 *Jan 19, 1965Mar 5, 1968Edwards Lab IncHeart valve for quick implantation having provision for ingrowth of tissueUS4345601 *Apr 7, 1980Aug 24, 1982Mamoru FukudaContinuous suturing deviceUS4485816 *Jun 25, 1981Dec 4, 1984AlchemiaShape-memory surgical staple apparatus and method for use in surgical suturingUS4548202 *Jun 20, 1983Oct 22, 1985Ethicon, Inc.Mesh tissue fastenersUS4595007 *Mar 14, 1983Jun 17, 1986Ethicon, Inc.Split ring type tissue fastenerUS4665906 *May 21, 1986May 19, 1987Raychem CorporationMedical devices incorporating sim alloy elementsUS4705516 *Nov 21, 1983Nov 10, 1987Barone Hector DSetting for a cardiac valveUS4932955 *Jun 29, 1984Jun 12, 1990Baxter International Inc.ClipUS5002563 *Feb 22, 1990Mar 26, 1991Raychem CorporationSutures utilizing shape memory alloysUS5002582 *Dec 8, 1989Mar 26, 1991Bio-Metric Systems, Inc.Preparation of polymeric surfaces via covalently attaching polymersUS5007921 *Oct 26, 1989Apr 16, 1991Brown Alan WSurgical stapleUS5026391 *Nov 14, 1989Jun 25, 1991Mcqueen David MCurved butterfly bileaflet prosthetic cardiac valveUS5156609 *May 3, 1991Oct 20, 1992Nakao Naomi LEndoscopic stapling device and methodUS5171252 *Feb 5, 1991Dec 15, 1992Friedland Thomas WSurgical fastening clip formed of a shape memory alloy, a method of making such a clip and a method of using such a clipUS5192303 *Mar 18, 1992Mar 9, 1993Mitek Surgical Products, Inc.Suture anchorUS5246443 *Apr 28, 1992Sep 21, 1993Christian MaiClip and osteosynthesis plate with dynamic compression and self-retentionUS5282829 *Aug 15, 1991Feb 1, 1994United States Surgical CorporationHollow body implantsUS5364406 *Aug 16, 1993Nov 15, 1994Sewell Jr FrankLaparoscopic surgical stapleUS5370685 *Jul 16, 1991Dec 6, 1994Stanford Surgical Technologies, Inc.Endovascular aortic valve replacementUS5464416 *Nov 10, 1992Nov 7, 1995Ethicon, Inc.Ligating clipUS5573543 *Mar 22, 1995Nov 12, 1996Ethicon, Inc.Endoscopic surgical instrument and staples for applying purse string suturesUS5618311 *Sep 28, 1994Apr 8, 1997Gryskiewicz; Joseph M.Surgical subcuticular fastener systemUS5660188 *May 30, 1995Aug 26, 1997Groiso; Jorge A.Procedure for applying an elastic clipUS5716370 *Feb 23, 1996Feb 10, 1998Williamson, Iv; WarrenMeans for replacing a heart valve in a minimally invasive mannerUS5717252 *Dec 2, 1996Feb 10, 1998Mitsui High-Tec, Inc.Solder-ball connected semiconductor device with a recessed chip mounting areaUS5718370 *May 23, 1996Feb 17, 1998Fort James CorporationPartially shielded microwave heating containerUS5720755 *Oct 2, 1995Feb 24, 1998Dakov; PepiTubular suturing device and methods of useUS5725554 *Oct 8, 1993Mar 10, 1998Richard-Allan Medical Industries, Inc.Surgical staple and staplerUS5779707 *Oct 3, 1995Jul 14, 1998Bertholet; MauriceLink piece for bony elementsUS5785713 *May 6, 1997Jul 28, 1998Jobe; Richard P.Surgical fixation apparatusUS5816370 *Nov 3, 1995Oct 6, 1998Rufas Pagid AktiengesellschaftDisc brake lining with a noise-damping plateUS5860992 *Jan 31, 1996Jan 19, 1999Heartport, Inc.Endoscopic suturing devices and methodsUS5891160 *Dec 4, 1997Apr 6, 1999Cardiovascular Technologies, LlcFastener delivery and deployment mechanism and method for placing the fastener in minimally invasive surgeryUS5902310 *Feb 21, 1997May 11, 1999Ethicon Endo-Surgery, Inc.Apparatus and method for marking tissueUS5908428 *Sep 19, 1997Jun 1, 1999United States Surgical CorporationStitching devices for heart valve replacement surgeryUS5921997 *Sep 19, 1997Jul 13, 1999Ethicon Endo-Surgery, Inc.Sterile occlusion fasteners and instrument and method for their placementUS5941890 *Jun 26, 1998Aug 24, 1999Ethicon Endo-Surgery, Inc.Implantable surgical markerUS5957940 *Oct 27, 1997Sep 28, 1999Eva CorporationFasteners for use in the surgical repair of aneurysmsUS5976183 *Jan 5, 1998Nov 2, 1999Medical Carbon Research Institute, LlcSewing ring for heart valve prosthesisUS6001110 *Jun 20, 1997Dec 14, 1999Boston Scientific CorporationHemostatic clipsUS6042607 *Feb 21, 1997Mar 28, 2000Cardiovascular Technologies LlcMeans and method of replacing a heart valve in a minimally invasive mannerUS6059787 *Apr 26, 1999May 9, 2000Allen; DrewCompression bone staple apparatus and methodUS6074401 *Jan 9, 1997Jun 13, 2000Coalescent Surgical, Inc.Pinned retainer surgical fasteners, instruments and methods for minimally invasive vascular and endoscopic surgeryUS6113611 *May 27, 1999Sep 5, 2000Advanced Vascular Technologies, LlcSurgical fastener and delivery systemUS6149658 *Jan 9, 1997Nov 21, 2000Coalescent Surgical, Inc.Sutured staple surgical fasteners, instruments and methods for minimally invasive vascular and endoscopic surgeryUS6152935 *Dec 11, 1998Nov 28, 2000Ethicon, Inc.Meniscal repair device having integral spring memberUS6162233 *Aug 6, 1999Dec 19, 2000Cardiovascular Technologies, LlcWire fasteners for use in minimally invasive surgery and means and methods for handling those fastenersUS6203553 *Sep 8, 1999Mar 20, 2001United States SurgicalStapling apparatus and method for heart valve replacementUS6220248 *Oct 21, 1998Apr 24, 2001Ethicon Endo-Surgery, Inc.Method for implanting a biopsy markerUS6241765 *Jul 15, 1999Jun 5, 2001Sulzer Carbomedics Inc.Stapled heart prosthesis and method of installing sameUS6248117 *Apr 16, 1999Jun 19, 2001Vital Access CorpAnastomosis apparatus for use in intraluminally directed vascular anastomosisUS6334446 *Apr 7, 1999Jan 1, 2002American Medical Systems, Inc.Medical sling procedures and anchor insertion methods and devicesUS6348054 *Feb 8, 2000Feb 19, 2002Drew AllenStapling method for fastening a first bone segment to a second bone segmentUS6358556 *Jan 23, 1998Mar 19, 2002Boston Scientific CorporationDrug release stent coatingUS6371983 *Oct 3, 2000Apr 16, 2002Ernest LaneBioprosthetic heart valveUS6626899 *Jul 3, 2001Sep 30, 2003Nidus Medical, LlcApparatus and methods for treating tissueUS6676671 *Mar 2, 2001Jan 13, 2004United States SurgicalStapling apparatus and method for heart valve replacementUS6702826 *Jun 22, 2001Mar 9, 2004Viacor, Inc.Automated annular plication for mitral valve repairUS20020035361 *Jul 3, 2001Mar 21, 2002Houser Russell A.Apparatus and methods for treating tissueUS20040193191 *Dec 19, 2003Sep 30, 2004Guided Delivery Systems, Inc.Devices and methods for heart valve repairUS20050107871 *Mar 30, 2004May 19, 2005Fidel RealyvasquezApparatus and methods for valve repair* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS7665647Sep 29, 2006Feb 23, 2010Ethicon Endo-Surgery, Inc.Surgical cutting and stapling device with closure apparatus for limiting maximum tissue compression forceUS7666193Jul 27, 2004Feb 23, 2010Guided Delivery Sytems, Inc.Delivery devices and methods for heart valve repairUS7669746Aug 31, 2005Mar 2, 2010Ethicon Endo-Surgery, Inc.Staple cartridges for forming staples having differing formed staple heightsUS7669747Jun 29, 2007Mar 2, 2010Ethicon Endo-Surgery, Inc.Washer for use with a surgical stapling instrumentUS7673781Feb 28, 2007Mar 9, 2010Ethicon Endo-Surgery, Inc.Surgical stapling device with staple driver that supports multiple wire diameter staplesUS7673782Jun 29, 2007Mar 9, 2010Ethicon Endo-Surgery, Inc.Surgical stapling instrument having a releasable buttress materialUS7717955Feb 28, 2005May 18, 2010Medtronic, Inc.Conformable prosthesis for implanting two-piece heart valves and methods for using themUS7722643Jul 29, 2002May 25, 2010Medtronic, Inc.Tissue connector apparatus and methodsUS7735703Jun 29, 2007Jun 15, 2010Ethicon Endo-Surgery, Inc.Re-loadable surgical stapling instrumentUS7744611Nov 19, 2003Jun 29, 2010Medtronic, Inc.Minimally invasive valve repair procedure and apparatusUS7753858Jul 27, 2004Jul 13, 2010Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS7753922Sep 4, 2003Jul 13, 2010Guided Delivery Systems, Inc.Devices and methods for cardiac annulus stabilization and treatmentUS7753924Jul 27, 2004Jul 13, 2010Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS7758637Jul 27, 2004Jul 20, 2010Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS7763040Feb 10, 2003Jul 27, 2010Medtronic, Inc.Tissue connector apparatus and methodsUS7793812Feb 14, 2008Sep 14, 2010Ethicon Endo-Surgery, Inc.Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatusUS7794475Sep 29, 2006Sep 14, 2010Ethicon Endo-Surgery, Inc.Surgical staples having compressible or crushable members for securing tissue therein and stapling instruments for deploying the sameUS7819296Feb 14, 2008Oct 26, 2010Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with retractable firing systemsUS7819297Feb 14, 2008Oct 26, 2010Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with reprocessible handle assemblyUS7819298Feb 14, 2008Oct 26, 2010Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with control features operable with one handUS7819915Dec 19, 2003Oct 26, 2010Edwards Lifesciences CorporationHeart valve holders and handling clips thereforUS7861906Feb 14, 2008Jan 4, 2011Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with articulatable componentsUS7866527Feb 14, 2008Jan 11, 2011Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with interlockable firing systemUS7879047Dec 10, 2003Feb 1, 2011Medtronic, Inc.Surgical connection apparatus and methodsUS7883538Sep 20, 2005Feb 8, 2011Guided Delivery Systems Inc.Methods and devices for terminationUS7892255Aug 28, 2003Feb 22, 2011Medtronic, Inc.Tissue connector apparatus and methodsUS7896892Apr 3, 2003Mar 1, 2011Medtronic, Inc.Multiple bias surgical fastenerUS7914544Dec 7, 2004Mar 29, 2011Medtronic, Inc.Minimally invasive valve repair procedure and apparatusUS7922762Jun 3, 2008Apr 12, 2011Guided Delivery Systems Inc.Devices and methods for cardiac annulus stabilization and treatmentUS7934630Feb 28, 2008May 3, 2011Ethicon Endo-Surgery, Inc.Staple cartridges for forming staples having differing formed staple heightsUS7938840Nov 18, 2003May 10, 2011Medtronic, Inc.Apparatus and methods for anastomosisUS7938847Jan 4, 2006May 10, 2011Tornier, Inc.Ring cinch assembly to attach bone to tissueUS7951197Apr 6, 2009May 31, 2011Medtronic, Inc.Two-piece prosthetic valves with snap-in connection and methods for useUS7955380 *Mar 17, 2006Jun 7, 2011Medtronic Vascular, Inc.Prosthesis fixation apparatus and methodsUS7959674Mar 3, 2004Jun 14, 2011Medtronic, Inc.Suture locking assembly and method of useUS7963973Sep 2, 2005Jun 21, 2011Medtronic, Inc.Multiple loop tissue connector apparatus and methodsUS7966799Jun 29, 2007Jun 28, 2011Ethicon Endo-Surgery, Inc.Method of manufacturing staplesUS7967857Jan 29, 2007Jun 28, 2011Medtronic, Inc.Gasket with spring collar for prosthetic heart valves and methods for making and using themUS7972377Aug 29, 2008Jul 5, 2011Medtronic, Inc.Bioprosthetic heart valveUS7976556Dec 21, 2006Jul 12, 2011Medtronic, Inc.Anastomosis apparatus and methodsUS7981153Mar 14, 2005Jul 19, 2011Medtronic, Inc.Biologically implantable prosthesis methods of usingUS8021161May 1, 2006Sep 20, 2011Edwards Lifesciences CorporationSimulated heart valve root for training and testingUS8021421Aug 22, 2003Sep 20, 2011Medtronic, Inc.Prosthesis heart valve fixturing deviceUS8025695Jan 31, 2003Sep 27, 2011Medtronic, Inc.Biologically implantable heart valve systemUS8029519Sep 14, 2006Oct 4, 2011Medtronic, Inc.Eversion apparatus and methodsUS8066724Jan 10, 2003Nov 29, 2011Medtronic, Inc.Anastomosis apparatus and methodsUS8066766Aug 20, 2007Nov 29, 2011Guided Delivery Systems Inc.Methods and devices for terminationUS8083793Feb 28, 2005Dec 27, 2011Medtronic, Inc.Two piece heart valves including multiple lobe valves and methods for implanting themUS8105345Jan 10, 2003Jan 31, 2012Medtronic, Inc.Anastomosis apparatus and methodsUS8113410Feb 9, 2011Feb 14, 2012Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with control featuresUS8118822Apr 5, 2001Feb 21, 2012Medtronic, Inc.Bridge clip tissue connector apparatus and methodsUS8147504 *May 5, 2008Apr 3, 2012Medtronic, Inc.Apparatus and methods for delivering fasteners during valve replacementUS8152822 *Nov 28, 2007Apr 10, 2012Cook Medical Technologies LlcCombination therapy hemostatic clipUS8157153Feb 4, 2011Apr 17, 2012Ethicon Endo-Surgery, Inc.Surgical instrument with force-feedback capabilitiesUS8161977Sep 23, 2008Apr 24, 2012Ethicon Endo-Surgery, Inc.Accessing data stored in a memory of a surgical instrumentUS8163014Apr 5, 2010Apr 24, 2012Medtronic, Inc.Conformable prostheses for implanting two-piece heart valves and methods for using themUS8167185Nov 18, 2010May 1, 2012Ethicon Endo-Surgery, Inc.Surgical instrument having recording capabilitiesUS8172124Feb 4, 2011May 8, 2012Ethicon Endo-Surgery, Inc.Surgical instrument having recording capabilitiesUS8177836Mar 10, 2009May 15, 2012Medtronic, Inc.Apparatus and methods for minimally invasive valve repairUS8186555Jan 31, 2006May 29, 2012Ethicon Endo-Surgery, Inc.Motor-driven surgical cutting and fastening instrument with mechanical closure systemUS8186560Oct 16, 2009May 29, 2012Ethicon Endo-Surgery, Inc.Surgical stapling systems and staple cartridges for deploying surgical staples with tissue compression featuresUS8196795Aug 13, 2010Jun 12, 2012Ethicon Endo-Surgery, Inc.Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatusUS8196796Feb 3, 2011Jun 12, 2012Ethicon Endo-Surgery, Inc.Shaft based rotary drive system for surgical instrumentsUS8211124Feb 5, 2007Jul 3, 2012Medtronic, Inc.Sealing clip, delivery systems, and methodsUS8211131Apr 5, 2011Jul 3, 2012Medtronic, Inc.Apparatus and methods for anastomosisUS8211169May 26, 2006Jul 3, 2012Medtronic, Inc.Gasket with collar for prosthetic heart valves and methods for using themUS8215531Jan 29, 2010Jul 10, 2012Ethicon Endo-Surgery, Inc.Surgical stapling instrument having a medical substance dispenserUS8220690Sep 29, 2006Jul 17, 2012Ethicon Endo-Surgery, Inc.Connected surgical staples and stapling instruments for deploying the sameUS8287555Dec 19, 2003Oct 16, 2012Guided Delivery Systems, Inc.Devices and methods for heart valve repairUS8287557Aug 20, 2007Oct 16, 2012Guided Delivery Systems, Inc.Methods and devices for terminationUS8292155Jun 2, 2011Oct 23, 2012Ethicon Endo-Surgery, Inc.Motor-driven surgical cutting and fastening instrument with tactile position feedbackUS8298251Feb 27, 2008Oct 30, 2012Medtronic, Inc.Anastomosis apparatus and methodsUS8308798Dec 10, 2009Nov 13, 2012Edwards Lifesciences CorporationQuick-connect prosthetic heart valve and methodsUS8317070Feb 28, 2007Nov 27, 2012Ethicon Endo-Surgery, Inc.Surgical stapling devices that produce formed staples having different lengthsUS8317808Sep 24, 2010Nov 27, 2012Covidien LpDevice and method for rolling and inserting a prosthetic patch into a body cavityUS8342376Jun 7, 2006Jan 1, 2013Cook Medical Technologies LlcMedical staplerUS8343173Jun 4, 2008Jan 1, 2013Guided Delivery Systems Inc.Delivery devices and methods for heart valve repairUS8348131Sep 29, 2006Jan 8, 2013Ethicon Endo-Surgery, Inc.Surgical stapling instrument with mechanical indicator to show levels of tissue compressionUS8348998Jun 23, 2010Jan 8, 2013Edwards Lifesciences CorporationUnitary quick connect prosthetic heart valve and deployment system and methodsUS8349003Apr 12, 2011Jan 8, 2013Medtronic, Inc.Suture locking assembly and method of useUS8353092Feb 7, 2011Jan 15, 2013Medtronic, Inc.Multiple bias surgical fastenerUS8353438Nov 19, 2009Jan 15, 2013Ethicon Endo-Surgery, Inc.Circular stapler introducer with rigid cap assembly configured for easy removalUS8353439Nov 19, 2009Jan 15, 2013Ethicon Endo-Surgery, Inc.Circular stapler introducer with radially-openable distal end portionUS8353921Aug 4, 2010Jan 15, 2013Medtronic, IncTissue connector apparatus and methodsUS8360297Sep 29, 2006Jan 29, 2013Ethicon Endo-Surgery, Inc.Surgical cutting and stapling instrument with self adjusting anvilUS8365976Sep 29, 2006Feb 5, 2013Ethicon Endo-Surgery, Inc.Surgical staples having dissolvable, bioabsorbable or biofragmentable portions and stapling instruments for deploying the sameUS8393514Sep 30, 2010Mar 12, 2013Ethicon Endo-Surgery, Inc.Selectively orientable implantable fastener cartridgeUS8394114Sep 26, 2003Mar 12, 2013Medtronic, Inc.Surgical connection apparatus and methodsUS8397971Feb 5, 2009Mar 19, 2013Ethicon Endo-Surgery, Inc.Sterilizable surgical instrumentUS8414577Nov 19, 2009Apr 9, 2013Ethicon Endo-Surgery, Inc.Surgical instruments and components for use in sterile environmentsUS8424740Nov 4, 2010Apr 23, 2013Ethicon Endo-Surgery, Inc.Surgical instrument having a directional switching mechanismUS8439244Jan 28, 2011May 14, 2013Ethicon Endo-Surgery, Inc.Surgical stapler fastening device with movable anvilUS8449625Oct 27, 2009May 28, 2013Edwards Lifesciences CorporationMethods of measuring heart valve annuluses for valve replacementUS8453905Jun 21, 2011Jun 4, 2013Ethicon Endo-Surgery, Inc.Surgical fastener for applying a large staple through a small delivery portUS8459520Jan 10, 2007Jun 11, 2013Ethicon Endo-Surgery, Inc.Surgical instrument with wireless communication between control unit and remote sensorUS8459525Feb 14, 2008Jun 11, 2013Ethicon Endo-Sugery, Inc.Motorized surgical cutting and fastening instrument having a magnetic drive train torque limiting deviceUS8460373Jul 1, 2011Jun 11, 2013Medtronic, Inc.Method for implanting a heart valve within an annulus of a patientUS8464923Jan 28, 2010Jun 18, 2013Ethicon Endo-Surgery, Inc.Surgical stapling devices for forming staples with different formed heightsUS8469252Jan 28, 2011Jun 25, 2013Ethicon Endo-Surgery, Inc.Surgical stapler fastening device with adjustable anvilUS8474677Sep 30, 2010Jul 2, 2013Ethicon Endo-Surgery, Inc.Fastener system comprising a retention matrix and a coverUS8479969Feb 9, 2012Jul 9, 2013Ethicon Endo-Surgery, Inc.Drive interface for operably coupling a manipulatable surgical tool to a robotUS8485412Sep 29, 2006Jul 16, 2013Ethicon Endo-Surgery, Inc.Surgical staples having attached drivers and stapling instruments for deploying the sameUS8491631Jan 3, 2007Jul 23, 2013Children's Medical Center CorporationTissue tackUS8499993Jun 12, 2012Aug 6, 2013Ethicon Endo-Surgery, Inc.Surgical staple cartridgeUS8500802Mar 8, 2011Aug 6, 2013Medtronic, Inc.Two-piece prosthetic valves with snap-in connection and methods for useUS8506625Aug 9, 2010Aug 13, 2013Edwards Lifesciences CorporationContoured sewing ring for a prosthetic mitral heart valveUS8517243Feb 14, 2011Aug 27, 2013Ethicon Endo-Surgery, Inc.Surgical instrument with wireless communication between control unit and remote sensorUS8517244Jul 9, 2012Aug 27, 2013Ethicon Endo-Surgery, Inc.Surgical stapling instrument having a medical substance dispenserUS8518060Apr 9, 2009Aug 27, 2013Medtronic, Inc.Medical clip with radial tines, system and method of using sameUS8529583Mar 31, 2000Sep 10, 2013Medtronic, Inc.Surgical clip removal apparatusUS8529599Aug 17, 2010Sep 10, 2013Covidien LpTissue tension detection systemUS8529600Sep 30, 2010Sep 10, 2013Ethicon Endo-Surgery, Inc.Fastener system comprising a retention matrixUS8534528Mar 1, 2011Sep 17, 2013Ethicon Endo-Surgery, Inc.Surgical instrument having a multiple rate directional switching mechanismUS8540128Jan 11, 2007Sep 24, 2013Ethicon Endo-Surgery, Inc.Surgical stapling device with a curved end effectorUS8540130Feb 8, 2011Sep 24, 2013Ethicon Endo-Surgery, Inc.Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatusUS8551162Dec 20, 2002Oct 8, 2013Medtronic, Inc.Biologically implantable prosthesisUS8567656Mar 28, 2011Oct 29, 2013Ethicon Endo-Surgery, Inc.Staple cartridges for forming staples having differing formed staple heightsUS8573461Feb 9, 2012Nov 5, 2013Ethicon Endo-Surgery, Inc.Surgical stapling instruments with cam-driven staple deployment arrangementsUS8573465Feb 9, 2012Nov 5, 2013Ethicon Endo-Surgery, Inc.Robotically-controlled surgical end effector system with rotary actuated closure systemsUS8574257Aug 10, 2009Nov 5, 2013Edwards Lifesciences CorporationSystem, device, and method for providing access in a cardiovascular environmentUS8584919Feb 14, 2008Nov 19, 2013Ethicon Endo-Sugery, Inc.Surgical stapling apparatus with load-sensitive firing mechanismUS8590762Jun 29, 2007Nov 26, 2013Ethicon Endo-Surgery, Inc.Staple cartridge cavity configurationsUS8602286Jan 20, 2010Dec 10, 2013Ethicon Endo-Surgery, Inc.Apparatus for feeding staples in a low profile surgical staplerUS8602287Jun 1, 2012Dec 10, 2013Ethicon Endo-Surgery, Inc.Motor driven surgical cutting instrumentUS8602288Feb 9, 2012Dec 10, 2013Ethicon Endo-Surgery. Inc.Robotically-controlled motorized surgical end effector system with rotary actuated closure systems having variable actuation speedsUS8603161Jul 6, 2009Dec 10, 2013Medtronic, Inc.Attachment device and methods of using the sameUS8608045Oct 10, 2008Dec 17, 2013Ethicon Endo-Sugery, Inc.Powered surgical cutting and stapling apparatus with manually retractable firing systemUS8616431Feb 9, 2012Dec 31, 2013Ethicon Endo-Surgery, Inc.Shiftable drive interface for robotically-controlled surgical toolUS8622274Feb 14, 2008Jan 7, 2014Ethicon Endo-Surgery, Inc.Motorized cutting and fastening instrument having control circuit for optimizing battery usageUS8622275Nov 19, 2009Jan 7, 2014Ethicon Endo-Surgery, Inc.Circular stapler introducer with rigid distal end portionUS8623080Sep 22, 2011Jan 7, 2014Medtronic, Inc.Biologically implantable prosthesis and methods of using the sameUS8636187Feb 3, 2011Jan 28, 2014Ethicon Endo-Surgery, Inc.Surgical stapling systems that produce formed staples having different lengthsUS8636736Feb 14, 2008Jan 28, 2014Ethicon Endo-Surgery, Inc.Motorized surgical cutting and fastening instrumentUS8641727Jun 3, 2008Feb 4, 2014Guided Delivery Systems, Inc.Devices and methods for heart valve repairUS8641757Jun 23, 2011Feb 4, 2014Edwards Lifesciences CorporationSystems for rapidly deploying surgical heart valvesUS8652120Jan 10, 2007Feb 18, 2014Ethicon Endo-Surgery, Inc.Surgical instrument with wireless communication between control unit and sensor transpondersUS8657174Feb 14, 2008Feb 25, 2014Ethicon Endo-Surgery, Inc.Motorized surgical cutting and fastening instrument having handle based power sourceUS8657178Jan 9, 2013Feb 25, 2014Ethicon Endo-Surgery, Inc.Surgical stapling apparatusUS8668130May 24, 2012Mar 11, 2014Ethicon Endo-Surgery, Inc.Surgical stapling systems and staple cartridges for deploying surgical staples with tissue compression featuresUS8668704Apr 24, 2009Mar 11, 2014Medtronic, Inc.Medical clip with tines, system and method of using sameUS8672208Mar 5, 2010Mar 18, 2014Ethicon Endo-Surgery, Inc.Surgical stapling instrument having a releasable buttress materialUS8684253May 27, 2011Apr 1, 2014Ethicon Endo-Surgery, Inc.Surgical instrument with wireless communication between a control unit of a robotic system and remote sensorUS8690960 *Oct 28, 2010Apr 8, 2014Covidien LpReinforced tissue patchUS8696742Oct 10, 2012Apr 15, 2014Edwards Lifesciences CorporationUnitary quick-connect prosthetic heart valve deployment methodsUS8720766Sep 29, 2006May 13, 2014Ethicon Endo-Surgery, Inc.Surgical stapling instruments and staplesUS8721650Mar 22, 2007May 13, 2014Tornier, Inc.Bone anchor installer and method of useUS8727197Jun 29, 2007May 20, 2014Ethicon Endo-Surgery, Inc.Staple cartridge cavity configuration with cooperative surgical stapleUS8734473Oct 25, 2012May 27, 2014Covidien LpDevice and method for rolling and inserting a prosthetic patch into a body cavityUS8734484 *Apr 21, 2009May 27, 2014Medtronic, Inc.System and method for closure of an internal opening in tissue, such as a trans-apical access openingUS8740034Sep 30, 2010Jun 3, 2014Ethicon Endo-Surgery, Inc.Surgical stapling instrument with interchangeable staple cartridge arrangementsUS8740037Sep 30, 2010Jun 3, 2014Ethicon Endo-Surgery, Inc.Compressible fastener cartridgeUS8740038Apr 29, 2011Jun 3, 2014Ethicon Endo-Surgery, Inc.Staple cartridge comprising a releasable portionUS8746529Dec 2, 2011Jun 10, 2014Ethicon Endo-Surgery, Inc.Accessing data stored in a memory of a surgical instrumentUS8746530Sep 28, 2012Jun 10, 2014Ethicon Endo-Surgery, Inc.Surgical instrument with wireless communication between control unit and remote sensorUS8746535Apr 29, 2011Jun 10, 2014Ethicon Endo-Surgery, Inc.Tissue thickness compensator comprising detachable portionsUS8747238Jun 28, 2012Jun 10, 2014Ethicon Endo-Surgery, Inc.Rotary drive shaft assemblies for surgical instruments with articulatable end effectorsUS8747463Aug 3, 2011Jun 10, 2014Medtronic, Inc.Methods of using a prosthesis fixturing deviceUS8752699Sep 30, 2010Jun 17, 2014Ethicon Endo-Surgery, Inc.Implantable fastener cartridge comprising bioabsorbable layersUS8752747Mar 20, 2012Jun 17, 2014Ethicon Endo-Surgery, Inc.Surgical instrument having recording capabilitiesUS8752749May 27, 2011Jun 17, 2014Ethicon Endo-Surgery, Inc.Robotically-controlled disposable motor-driven loading unitUS8753359Jul 12, 2010Jun 17, 2014Covidien LpDevice and method for deploying and attaching an implant to a biological tissueUS8757465Sep 30, 2010Jun 24, 2014Ethicon Endo-Surgery, Inc.Fastener system comprising a retention matrix and an alignment matrixUS8758391Feb 14, 2008Jun 24, 2014Ethicon Endo-Surgery, Inc.Interchangeable tools for surgical instrumentsUS8758406Mar 5, 2008Jun 24, 2014Tomier, Inc.Tack anchor systems, bone anchor systems, and methods of useUS8763875Mar 6, 2013Jul 1, 2014Ethicon Endo-Surgery, Inc.End effector for use with a surgical fastening instrumentUS8763877Sep 30, 2010Jul 1, 2014Ethicon Endo-Surgery, Inc.Surgical instruments with reconfigurable shaft segmentsUS8763879Mar 1, 2011Jul 1, 2014Ethicon Endo-Surgery, Inc.Accessing data stored in a memory of surgical instrumentUS8777004Apr 29, 2011Jul 15, 2014Ethicon Endo-Surgery, Inc.Compressible staple cartridge comprising alignment membersUS8783541Feb 9, 2012Jul 22, 2014Frederick E. Shelton, IVRobotically-controlled surgical end effector systemUS8783542Sep 30, 2010Jul 22, 2014Ethicon Endo-Surgery, Inc.Fasteners supported by a fastener cartridge supportUS8789741Sep 23, 2011Jul 29, 2014Ethicon Endo-Surgery, Inc.Surgical instrument with trigger assembly for generating multiple actuation motionsUS8790367Feb 5, 2009Jul 29, 2014Guided Delivery Systems Inc.Multi-window guide tunnelUS8795298Oct 9, 2009Aug 5, 2014Guided Delivery Systems Inc.Tether tensioning devices and related methodsUS8800838Feb 9, 2012Aug 12, 2014Ethicon Endo-Surgery, Inc.Robotically-controlled cable-based surgical end effectorsUS8808314Sep 27, 2010Aug 19, 2014Covidien LpDevice and method for deploying and attaching an implant to a biological tissueUS8814024Sep 30, 2010Aug 26, 2014Ethicon Endo-Surgery, Inc.Fastener system comprising a plurality of connected retention matrix elementsUS8820603Mar 1, 2011Sep 2, 2014Ethicon Endo-Surgery, Inc.Accessing data stored in a memory of a surgical instrumentUS8820605Feb 9, 2012Sep 2, 2014Ethicon Endo-Surgery, Inc.Robotically-controlled surgical instrumentsUS8821538Nov 19, 2010Sep 2, 2014Peter Karl JohanssonImplantable tissue structure modifiers and methods for using the sameUS8821569Apr 30, 2007Sep 2, 2014Medtronic, Inc.Multiple component prosthetic heart valve assemblies and methods for delivering themUS8840003Sep 30, 2010Sep 23, 2014Ethicon Endo-Surgery, Inc.Surgical stapling instrument with compact articulation control arrangementUS8840603Jun 3, 2010Sep 23, 2014Ethicon Endo-Surgery, Inc.Surgical instrument with wireless communication between control unit and sensor transpondersUS8844789Feb 9, 2012Sep 30, 2014Ethicon Endo-Surgery, Inc.Automated end effector component reloading system for use with a robotic systemUS8845720Sep 20, 2011Sep 30, 2014Edwards Lifesciences CorporationProsthetic heart valve frame with flexible commissuresUS8857694Apr 29, 2011Oct 14, 2014Ethicon Endo-Surgery, Inc.Staple cartridge loading assemblyUS8864007Sep 30, 2010Oct 21, 2014Ethicon Endo-Surgery, Inc.Implantable fastener cartridge having a non-uniform arrangementUS8864009Apr 29, 2011Oct 21, 2014Ethicon Endo-Surgery, Inc.Tissue thickness compensator for a surgical stapler comprising an adjustable anvilUS8875971Dec 1, 2010Nov 4, 2014Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with interlockable firing systemUS8888794 *Jul 26, 2013Nov 18, 2014Cardica, Inc.Mitral valve treatmentUS8888811Jul 12, 2010Nov 18, 2014Covidien LpDevice and method for attaching an implant to biological tissueUS8893946Mar 28, 2007Nov 25, 2014Ethicon Endo-Surgery, Inc.Laparoscopic tissue thickness and clamp load measuring devicesUS8893949Sep 23, 2011Nov 25, 2014Ethicon Endo-Surgery, Inc.Surgical stapler with floating anvilUS8899463Sep 30, 2010Dec 2, 2014Ethicon Endo-Surgery, Inc.Surgical staple cartridges supporting non-linearly arranged staples and surgical stapling instruments with common staple-forming pocketsUS8899465Mar 5, 2013Dec 2, 2014Ethicon Endo-Surgery, Inc.Staple cartridge comprising drivers for deploying a plurality of staplesUS8899466Nov 19, 2009Dec 2, 2014Ethicon Endo-Surgery, Inc.Devices and methods for introducing a surgical circular stapling instrument into a patientUS8906045Jul 7, 2010Dec 9, 2014Covidien LpArticulating patch deployment device and method of useUS8911471Sep 14, 2012Dec 16, 2014Ethicon Endo-Surgery, Inc.Articulatable surgical deviceUS8925782Sep 30, 2010Jan 6, 2015Ethicon Endo-Surgery, Inc.Implantable fastener cartridge comprising multiple layersUS8925788Mar 3, 2014Jan 6, 2015Ethicon Endo-Surgery, Inc.End effectors for surgical stapling instrumentsUS8931682May 27, 2011Jan 13, 2015Ethicon Endo-Surgery, Inc.Robotically-controlled shaft based rotary drive systems for surgical instrumentsUS8973803Sep 9, 2010Mar 10, 2015Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with control features operable with one handUS8973804Mar 18, 2014Mar 10, 2015Ethicon Endo-Surgery, Inc.Cartridge assembly having a buttressing memberUS8978954Apr 29, 2011Mar 17, 2015Ethicon Endo-Surgery, Inc.Staple cartridge comprising an adjustable distal portionUS8978956Sep 30, 2010Mar 17, 2015Ethicon Endo-Surgery, Inc.Jaw closure arrangements for surgical instrumentsUS8986374May 10, 2011Mar 24, 2015Edwards Lifesciences CorporationProsthetic heart valveUS8991676Jun 29, 2007Mar 31, 2015Ethicon Endo-Surgery, Inc.Surgical staple having a slidable crownUS8991677May 21, 2014Mar 31, 2015Ethicon Endo-Surgery, Inc.Detachable motor powered surgical instrumentUS8992422May 27, 2011Mar 31, 2015Ethicon Endo-Surgery, Inc.Robotically-controlled endoscopic accessory channelUS8998058May 20, 2014Apr 7, 2015Ethicon Endo-Surgery, Inc.Detachable motor powered surgical instrumentUS9005230Jan 18, 2013Apr 14, 2015Ethicon Endo-Surgery, Inc.Motorized surgical instrumentUS9005241May 5, 2014Apr 14, 2015Covidien LpMeans and method for reversibly connecting a patch to a patch deployment deviceUS9005277Dec 21, 2012Apr 14, 2015Edwards Lifesciences CorporationUnitary quick-connect prosthetic heart valve deployment systemUS9005278Oct 25, 2012Apr 14, 2015Edwards Lifesciences CorporationQuick-connect prosthetic heart valveUS9028494Jun 28, 2012May 12, 2015Ethicon Endo-Surgery, Inc.Interchangeable end effector coupling arrangementUS9028519Feb 7, 2011May 12, 2015Ethicon Endo-Surgery, Inc.Motorized surgical instrumentUS9033203Sep 30, 2010May 19, 2015Ethicon Endo-Surgery, Inc.Fastening instrument for deploying a fastener system comprising a retention matrixUS9034002Jul 26, 2013May 19, 2015Covidien LpLock bar spring and clip for implant deployment deviceUS9044227Sep 30, 2010Jun 2, 2015Ethicon Endo-Surgery, Inc.Collapsible fastener cartridgeUS9044228Sep 30, 2010Jun 2, 2015Ethicon Endo-Surgery, Inc.Fastener system comprising a plurality of fastener cartridgesUS9044230Feb 13, 2012Jun 2, 2015Ethicon Endo-Surgery, Inc.Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion statusUS9044235Jul 26, 2013Jun 2, 2015Covidien LpMagnetic clip for implant deployment deviceUS9050083Sep 23, 2008Jun 9, 2015Ethicon Endo-Surgery, Inc.Motorized surgical instrumentUS9050084Sep 23, 2011Jun 9, 2015Ethicon Endo-Surgery, Inc.Staple cartridge including collapsible deck arrangementUS9055941Sep 23, 2011Jun 16, 2015Ethicon Endo-Surgery, Inc.Staple cartridge including collapsible deckUS9060770May 27, 2011Jun 23, 2015Ethicon Endo-Surgery, Inc.Robotically-driven surgical instrument with E-beam driverUS9066719 *Mar 11, 2010Jun 30, 2015Endogene LimitedDevice and method for delivering shape-memory staplesUS9072513Aug 6, 2008Jul 7, 2015Guided Delivery Systems Inc.Methods and devices for terminationUS9072515Jun 25, 2014Jul 7, 2015Ethicon Endo-Surgery, Inc.Surgical stapling apparatusUS9072535May 27, 2011Jul 7, 2015Ethicon Endo-Surgery, Inc.Surgical stapling instruments with rotatable staple deployment arrangementsUS9072536Jun 28, 2012Jul 7, 2015Ethicon Endo-Surgery, Inc.Differential locking arrangements for rotary powered surgical instrumentsUS9078747Nov 13, 2012Jul 14, 2015Edwards Lifesciences CorporationAnchoring device for replacing or repairing a heart valveUS9084601Mar 15, 2013Jul 21, 2015Ethicon Endo-Surgery, Inc.Detachable motor powered surgical instrumentUS9095339May 19, 2014Aug 4, 2015Ethicon Endo-Surgery, Inc.Detachable motor powered surgical instrumentUS9101358Jun 15, 2012Aug 11, 2015Ethicon Endo-Surgery, Inc.Articulatable surgical instrument comprising a firing driveUS9101385Jun 28, 2012Aug 11, 2015Ethicon Endo-Surgery, Inc.Electrode connections for rotary driven surgical toolsUS9107726May 8, 2014Aug 18, 2015Covidien LpDevice and method for deploying and attaching an implant to a biological tissueUS9113862Sep 30, 2010Aug 25, 2015Ethicon Endo-Surgery, Inc.Surgical stapling instrument with a variable staple forming systemUS9113864Sep 30, 2010Aug 25, 2015Ethicon Endo-Surgery, Inc.Surgical cutting and fastening instruments with separate and distinct fastener deployment and tissue cutting systemsUS9113865Apr 29, 2011Aug 25, 2015Ethicon Endo-Surgery, Inc.Staple cartridge comprising a layerUS9113874Jun 24, 2014Aug 25, 2015Ethicon Endo-Surgery, Inc.Surgical instrument systemUS9119657Jun 28, 2012Sep 1, 2015Ethicon Endo-Surgery, Inc.Rotary actuatable closure arrangement for surgical end effectorUS9125662Jun 28, 2012Sep 8, 2015Ethicon Endo-Surgery, Inc.Multi-axis articulating and rotating surgical toolsUS9138225Feb 26, 2013Sep 22, 2015Ethicon Endo-Surgery, Inc.Surgical stapling instrument with an articulatable end effectorUS9149274Feb 17, 2011Oct 6, 2015Ethicon Endo-Surgery, Inc.Articulating endoscopic accessory channelUS9155617Apr 18, 2014Oct 13, 2015Edwards Lifesciences CorporationProsthetic mitral valveUS9168038Apr 29, 2011Oct 27, 2015Ethicon Endo-Surgery, Inc.Staple cartridge comprising a tissue thickness compensatorUS9179911May 23, 2014Nov 10, 2015Ethicon Endo-Surgery, Inc.End effector for use with a surgical fastening instrumentUS9179912May 27, 2011Nov 10, 2015Ethicon Endo-Surgery, Inc.Robotically-controlled motorized surgical cutting and fastening instrumentUS9180005Dec 5, 2014Nov 10, 2015Millipede, Inc.Adjustable endolumenal mitral valve ringUS9186143Jun 25, 2014Nov 17, 2015Ethicon Endo-Surgery, Inc.Robotically-controlled shaft based rotary drive systems for surgical instrumentsUS9192471Jan 8, 2007Nov 24, 2015Millipede, Inc.Device for translumenal reshaping of a mitral valve annulusUS9204878Aug 14, 2014Dec 8, 2015Ethicon Endo-Surgery, Inc.Surgical stapling apparatus with interlockable firing systemUS9204879Jun 28, 2012Dec 8, 2015Ethicon Endo-Surgery, Inc.Flexible drive memberUS9204880Mar 28, 2012Dec 8, 2015Ethicon Endo-Surgery, Inc.Tissue thickness compensator comprising capsules defining a low pressure environmentUS9211120Mar 28, 2012Dec 15, 2015Ethicon Endo-Surgery, Inc.Tissue thickness compensator comprising a plurality of medicamentsUS9211121Jan 13, 2015Dec 15, 2015Ethicon Endo-Surgery, Inc.Surgical stapling apparatusUS9216019Sep 23, 2011Dec 22, 2015Ethicon Endo-Surgery, Inc.Surgical stapler with stationary staple driversUS9220500Mar 28, 2012Dec 29, 2015Ethicon Endo-Surgery, Inc.Tissue thickness compensator comprising structure to produce a resilient loadUS9220501Mar 28, 2012Dec 29, 2015Ethicon Endo-Surgery, Inc.Tissue thickness compensatorsUS9226751Jun 28, 2012Jan 5, 2016Ethicon Endo-Surgery, Inc.Surgical instrument system including replaceable end effectorsUS9226825Jul 27, 2004Jan 5, 2016Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS9232941Mar 28, 2012Jan 12, 2016Ethicon Endo-Surgery, Inc.Tissue thickness compensator comprising a reservoirUS9237891May 27, 2011Jan 19, 2016Ethicon Endo-Surgery, Inc.Robotically-controlled surgical stapling devices that produce formed staples having different lengthsUS9241714Mar 28, 2012Jan 26, 2016Ethicon Endo-Surgery, Inc.Tissue thickness compensator and method for making the sameUS9248016Mar 3, 2010Feb 2, 2016Edwards Lifesciences CorporationProsthetic heart valve systemUS9259222Nov 29, 2012Feb 16, 2016Cook Medical Technologies LlcMedical staplerUS9271799Jun 25, 2014Mar 1, 2016Ethicon Endo-Surgery, LlcRobotic surgical system with removable motor housingUS9272406Feb 8, 2013Mar 1, 2016Ethicon Endo-Surgery, LlcFastener cartridge comprising a cutting member for releasing a tissue thickness compensatorUS9277919Mar 28, 2012Mar 8, 2016Ethicon Endo-Surgery, LlcTissue thickness compensator comprising fibers to produce a resilient loadUS9282962Feb 8, 2013Mar 15, 2016Ethicon Endo-Surgery, LlcAdhesive film laminateUS9282966Feb 7, 2014Mar 15, 2016Ethicon Endo-Surgery, Inc.Surgical stapling instrumentUS9282974Jun 28, 2012Mar 15, 2016Ethicon Endo-Surgery, LlcEmpty clip cartridge lockoutUS9283054Aug 23, 2013Mar 15, 2016Ethicon Endo-Surgery, LlcInteractive displaysUS9289206Dec 15, 2014Mar 22, 2016Ethicon Endo-Surgery, LlcLateral securement members for surgical staple cartridgesUS9289256Jun 28, 2012Mar 22, 2016Ethicon Endo-Surgery, LlcSurgical end effectors having angled tissue-contacting surfacesUS9295464Apr 29, 2011Mar 29, 2016Ethicon Endo-Surgery, Inc.Surgical stapler anvil comprising a plurality of forming pocketsUS9301752Mar 28, 2012Apr 5, 2016Ethicon Endo-Surgery, LlcTissue thickness compensator comprising a plurality of capsulesUS9301753Mar 28, 2012Apr 5, 2016Ethicon Endo-Surgery, LlcExpandable tissue thickness compensatorUS9301755Apr 29, 2011Apr 5, 2016Ethicon Endo-Surgery, LlcCompressible staple cartridge assemblyUS9301759Feb 9, 2012Apr 5, 2016Ethicon Endo-Surgery, LlcRobotically-controlled surgical instrument with selectively articulatable end effectorUS9301826Jul 26, 2013Apr 5, 2016Covidien LpLock bar spring and clip for implant deployment deviceUS9307986Mar 1, 2013Apr 12, 2016Ethicon Endo-Surgery, LlcSurgical instrument soft stopUS9307988Oct 28, 2013Apr 12, 2016Ethicon Endo-Surgery, LlcStaple cartridges for forming staples having differing formed staple heightsUS9314245 *Jun 8, 2012Apr 19, 2016Depuy Mitek, LlcSurgical fasteners and methods and devices for deploying a surgical fastenerUS9314334Nov 25, 2013Apr 19, 2016Edwards Lifesciences CorporationConformal expansion of prosthetic devices to anatomical shapesUS9320520Aug 19, 2015Apr 26, 2016Ethicon Endo-Surgery, Inc.Surgical instrument systemUS9320521Oct 29, 2012Apr 26, 2016Ethicon Endo-Surgery, LlcSurgical instrumentUS9320523Mar 28, 2012Apr 26, 2016Ethicon Endo-Surgery, LlcTissue thickness compensator comprising tissue ingrowth featuresUS9326767Mar 1, 2013May 3, 2016Ethicon Endo-Surgery, LlcJoystick switch assemblies for surgical instrumentsUS9326768Mar 12, 2013May 3, 2016Ethicon Endo-Surgery, LlcStaple cartridges for forming staples having differing formed staple heightsUS9326769Mar 6, 2013May 3, 2016Ethicon Endo-Surgery, LlcSurgical instrumentUS9326770Mar 6, 2013May 3, 2016Ethicon Endo-Surgery, LlcSurgical instrumentUS9332974Mar 28, 2012May 10, 2016Ethicon Endo-Surgery, LlcLayered tissue thickness compensatorUS9332984Mar 27, 2013May 10, 2016Ethicon Endo-Surgery, LlcFastener cartridge assembliesUS9332987Mar 14, 2013May 10, 2016Ethicon Endo-Surgery, LlcControl arrangements for a drive member of a surgical instrumentUS9333078Nov 22, 2013May 10, 2016Medtronic, Inc.Heart valve assembliesUS9345481Mar 13, 2013May 24, 2016Ethicon Endo-Surgery, LlcStaple cartridge tissue thickness sensor systemUS9351726Mar 14, 2013May 31, 2016Ethicon Endo-Surgery, LlcArticulation control system for articulatable surgical instrumentsUS9351727Mar 14, 2013May 31, 2016Ethicon Endo-Surgery, LlcDrive train control arrangements for modular surgical instrumentsUS9351730Mar 28, 2012May 31, 2016Ethicon Endo-Surgery, LlcTissue thickness compensator comprising channelsUS9358003Mar 1, 2013Jun 7, 2016Ethicon Endo-Surgery, LlcElectromechanical surgical device with signal relay arrangementUS9358005Jun 22, 2015Jun 7, 2016Ethicon Endo-Surgery, LlcEnd effector layer including holding featuresUS9364230Jun 28, 2012Jun 14, 2016Ethicon Endo-Surgery, LlcSurgical stapling instruments with rotary joint assembliesUS9364233Mar 28, 2012Jun 14, 2016Ethicon Endo-Surgery, LlcTissue thickness compensators for circular surgical staplersUS9370358Oct 19, 2012Jun 21, 2016Ethicon Endo-Surgery, LlcMotor-driven surgical cutting and fastening instrument with tactile position feedbackUS9370364Mar 5, 2013Jun 21, 2016Ethicon Endo-Surgery, LlcPowered surgical cutting and stapling apparatus with manually retractable firing systemUS9370370Nov 22, 2005Jun 21, 2016Boston Scientific Scimed, Inc.Shape memory hemostasis bandUS9370418Mar 12, 2013Jun 21, 2016Edwards Lifesciences CorporationRapidly deployable surgical heart valvesUS9386983May 27, 2011Jul 12, 2016Ethicon Endo-Surgery, LlcRobotically-controlled motorized surgical instrumentUS9386984Feb 8, 2013Jul 12, 2016Ethicon Endo-Surgery, LlcStaple cartridge comprising a releasable coverUS9386988Mar 28, 2012Jul 12, 2016Ethicon End-Surgery, LLCRetainer assembly including a tissue thickness compensatorUS9393002Jul 26, 2013Jul 19, 2016Covidien LpClip for implant deployment deviceUS9393015May 10, 2013Jul 19, 2016Ethicon Endo-Surgery, LlcMotor driven surgical fastener device with cutting member reversing mechanismUS9393093Jul 26, 2013Jul 19, 2016Covidien LpClip for implant deployment deviceUS9398911Mar 1, 2013Jul 26, 2016Ethicon Endo-Surgery, LlcRotary powered surgical instruments with multiple degrees of freedomUS9398944Dec 19, 2012Jul 26, 2016Covidien LpLock bar spring and clip for implant deployment deviceUS9402626Jul 18, 2012Aug 2, 2016Ethicon Endo-Surgery, LlcRotary actuatable surgical fastener and cutterUS9402719Apr 23, 2012Aug 2, 2016Medtronic, Inc.Conformable prostheses for implanting two-piece heart valves and methods for using themUS9402720Jan 12, 2010Aug 2, 2016Valve Medical Ltd.Modular percutaneous valve structure and delivery methodUS9408604Feb 28, 2014Aug 9, 2016Ethicon Endo-Surgery, LlcSurgical instrument comprising a firing system including a compliant portionUS9408606Jun 28, 2012Aug 9, 2016Ethicon Endo-Surgery, LlcRobotically powered surgical device with manually-actuatable reversing systemUS9414838Mar 28, 2012Aug 16, 2016Ethicon Endo-Surgery, LlcTissue thickness compensator comprised of a plurality of materialsUS9433419Mar 28, 2012Sep 6, 2016Ethicon Endo-Surgery, Inc.Tissue thickness compensator comprising a plurality of layersUS9439649Dec 12, 2012Sep 13, 2016Ethicon Endo-Surgery, LlcSurgical instrument having force feedback capabilitiesUS9439762Jan 23, 2013Sep 13, 2016Edwards Lifesciences CorporationMethods of implant of a heart valve with a convertible sewing ringUS9445805Nov 16, 2010Sep 20, 2016Tornier, Inc.Bone implant with convertible suture attachmentUS9445813Aug 23, 2013Sep 20, 2016Ethicon Endo-Surgery, LlcClosure indicator systems for surgical instrumentsUS9451958Aug 5, 2013Sep 27, 2016Ethicon Endo-Surgery, LlcSurgical instrument with firing actuator lockoutUS9468438Mar 1, 2013Oct 18, 2016Eticon Endo-Surgery, LLCSensor straightened end effector during removal through trocarUS9468527Jun 12, 2014Oct 18, 2016Edwards Lifesciences CorporationCardiac implant with integrated suture fastenersUS9468528Jan 15, 2014Oct 18, 2016Guided Delivery Systems, Inc.Devices and methods for heart valve repairUS9480476Mar 28, 2012Nov 1, 2016Ethicon Endo-Surgery, LlcTissue thickness compensator comprising resilient membersUS9486214May 20, 2013Nov 8, 2016Ethicon Endo-Surgery, LlcMotor driven surgical fastener device with switching system configured to prevent firing initiation until activatedUS9492167Mar 14, 2013Nov 15, 2016Ethicon Endo-Surgery, LlcArticulatable surgical device with rotary driven cutting memberUS9498219Jun 30, 2015Nov 22, 2016Ethicon Endo-Surgery, LlcDetachable motor powered surgical instrumentUS9504566Jun 19, 2015Nov 29, 2016Edwards Lifesciences CorporationSurgical heart valves identifiable post-implantUS9510828Aug 23, 2013Dec 6, 2016Ethicon Endo-Surgery, LlcConductor arrangements for electrically powered surgical instruments with rotatable end effectorsUS9510830Oct 23, 2014Dec 6, 2016Ethicon Endo-Surgery, LlcStaple cartridgeUS9510931 *Apr 4, 2014Dec 6, 2016Covidien LpReinforced tissue patchUS9517063Mar 28, 2012Dec 13, 2016Ethicon Endo-Surgery, LlcMovable member for use with a tissue thickness compensatorUS9517068Aug 5, 2013Dec 13, 2016Ethicon Endo-Surgery, LlcSurgical instrument with automatically-returned firing memberUS9522029Mar 12, 2013Dec 20, 2016Ethicon Endo-Surgery, LlcMotorized surgical cutting and fastening instrument having handle based power sourceUS20030068744 *Jul 23, 2002Apr 10, 2003Genentech, Inc.Secreted and transmembrane polypeptides and nucleic acids encoding the sameUS20040050393 *Jan 10, 2003Mar 18, 2004Steve GoldenAnastomosis apparatus and methodsUS20040138741 *Dec 19, 2003Jul 15, 2004Robert StobieHeart valve holders and handling clips thereforUS20040193191 *Dec 19, 2003Sep 30, 2004Guided Delivery Systems, Inc.Devices and methods for heart valve repairUS20040243227 *Mar 2, 2004Dec 2, 2004Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS20050055087 *Sep 4, 2003Mar 10, 2005Guided Delivery Systems, Inc.Devices and methods for cardiac annulus stabilization and treatmentUS20050065550 *Jul 27, 2004Mar 24, 2005Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS20050107811 *Jul 27, 2004May 19, 2005Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS20050107812 *Jul 27, 2004May 19, 2005Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS20050119523 *Aug 27, 2004Jun 2, 2005Guided Delivery Systems, Inc.Cardiac visualization devices and methodsUS20050216078 *May 24, 2005Sep 29, 2005Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS20050228494 *Mar 29, 2004Oct 13, 2005Salvador MarquezControlled separation heart valve frameUS20050245932 *Apr 15, 2005Nov 3, 2005Fanton Gary SApparatus and methods for securing tissue to boneUS20060025750 *Jul 27, 2004Feb 2, 2006Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS20060025784 *Jul 27, 2004Feb 2, 2006Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS20060025787 *Sep 27, 2005Feb 2, 2006Guided Delivery Systems, Inc.Devices and methods for heart valve repairUS20060058817 *Jul 27, 2004Mar 16, 2006Guided Delivery Systems, Inc.Delivery devices and methods for heart valve repairUS20060122634 *Dec 3, 2004Jun 8, 2006Ino Takashi HApparatus and method for delivering fasteners during valve replacementUS20060129188 *Oct 20, 2005Jun 15, 2006Starksen Niel FRemodeling a cardiac annulusUS20060276726 *Jun 5, 2006Dec 7, 2006Holsten Henry ETissue tension detection systemUS20060282081 *Jan 4, 2006Dec 14, 2006Fanton Gary SApparatus and method for securing tissue to bone with a sutureUS20060282082 *Jan 23, 2006Dec 14, 2006Fanton Gary SApparatus and method for securing tissue to bone with a sutureUS20060282083 *Jan 23, 2006Dec 14, 2006Fanton Gary SApparatus and method for securing tissue to bone with a sutureUS20060282118 *Jun 7, 2006Dec 14, 2006Wilson-Cook Medical Inc.Medical staplerUS20070055206 *Aug 10, 2005Mar 8, 2007Guided Delivery Systems, Inc.Methods and devices for deployment of tissue anchorsUS20070083234 *Sep 29, 2006Apr 12, 2007Shelton Frederick E IvSurgical stapling instruments having flexible channel and anvil features for adjustable staple heightsUS20070118162 *Nov 22, 2005May 24, 2007Michael Abi-KheirsShape memory hemostasis bandUS20070156148 *Jan 4, 2006Jul 5, 2007Fanton Gary SRing cinch assembly to attach bone to tissueUS20070156149 *Jan 23, 2006Jul 5, 2007Fanton Gary SRing cinch assembly to attach bone to tissueUS20070156150 *Aug 14, 2006Jul 5, 2007Fanton Gary SRing cinch assembly to attach bone to tissueUS20070156176 *Jan 23, 2006Jul 5, 2007Fanton Gary SRing cinch assembly to attach bone to tissueUS20070170225 *Mar 30, 2007Jul 26, 2007Ethicon Endo-Surgery, Inc.Disposable loading unit and surgical instruments including sameUS20070219627 *Mar 17, 2006Sep 20, 2007Medtronic Vascular, Inc.Prosthesis Fixation Apparatus and MethodsUS20070254273 *May 1, 2006Nov 1, 2007Hugues LafranceSimulated heart valve root for training and testingUS20070255317 *Mar 22, 2007Nov 1, 2007Fanton Gary SSuture passer devices and uses thereofUS20070260259 *Mar 22, 2007Nov 8, 2007Fanton Gary SBone anchor installer and method of useUS20070262116 *Feb 28, 2007Nov 15, 2007Hueil Joseph CSurgical stapling device with multiple stacked actuator wedge cams for driving staple driversUS20080045977 *Aug 20, 2007Feb 21, 2008John ToMethods and devices for terminationUS20080045982 *Aug 20, 2007Feb 21, 2008John ToDevices and methods for anchoring tissueUS20080045983 *Aug 20, 2007Feb 21, 2008John ToDevices and methods for anchoring tissueUS20080051832 *Aug 20, 2007Feb 28, 2008John ToDevices and methods for anchoring tissueUS20080065154 *Sep 8, 2006Mar 13, 2008Warsaw Orthopedic, IncSurgical stapleUS20080078804 *Sep 29, 2006Apr 3, 2008Shelton Frederick ESurgical cutting and stapling instrument with self adjusting anvilUS20080082115 *Jun 29, 2007Apr 3, 2008Morgan Jerome RMethod of manufacturing staplesUS20080082124 *Sep 29, 2006Apr 3, 2008Hess Christopher JSurgical staples having compressible or crushable members for securing tissue therein and stapling instruments for deploying the sameUS20080147092 *Oct 23, 2006Jun 19, 2008Michael RoggeHybrid energy instrument combined with clip application capabilityUS20080167713 *Jan 8, 2007Jul 10, 2008Bolling Steven FReconfiguring Heart FeaturesUS20080188875 *Feb 6, 2007Aug 7, 2008Sarkis YeretsianBloodless and painless surgical methodUS20080228032 *Jun 2, 2008Sep 18, 2008Guided Delivery Systems, Inc.Cardiac visualization devices and methodsUS20080234701 *Jun 2, 2008Sep 25, 2008Guided Delivery Systems, Inc.Devices and methods for heart valve repairUS20080234702 *Jun 3, 2008Sep 25, 2008Guided Delivery Systems, Inc.Devices and methods for heart valve repairUS20080234815 *Jun 3, 2008Sep 25, 2008Guided Delivery Systems, Inc.Devices and methods for cardiac annulus stabilization and treatmentUS20080275469 *Mar 5, 2008Nov 6, 2008Fanton Gary STack anchor systems, bone anchor systems, and methods of useUS20080287989 *May 13, 2008Nov 20, 2008Arch Day Design, LlcTissue holding implantsUS20090036903 *May 5, 2008Feb 5, 2009Arbor Surgical Technologies, Inc.Apparatus and methods for delivering fasteners during valve replacementUS20090182419 *Mar 19, 2009Jul 16, 2009Millipede LlcReconfiguring heart featuresUS20090206136 *Feb 14, 2008Aug 20, 2009Ethicon Endo-Surgery, Inc.Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatusUS20090275957 *May 1, 2008Nov 5, 2009Harris Jason LClip and delivery assembly used in forming a tissue foldUS20090306681 *Jan 30, 2007Dec 10, 2009Del Nido Pedro JTissue tackUS20090318957 *Sep 1, 2009Dec 24, 2009Viola Frank JExpandable backspan stapleUS20100016873 *Nov 28, 2007Jan 21, 2010Gayzik Caroline MCombination therapy hemostatic clipUS20100063363 *Aug 10, 2009Mar 11, 2010Hamman Baron LSystem, device, and method for providing access in a cardiovascular environmentUS20100121433 *Sep 21, 2009May 13, 2010Millipede Llc, A Corporation Of MichiganReconfiguring heart featuresUS20100185275 *Jan 12, 2010Jul 22, 2010Valve Medical Ltd.Modular percutaneous valve structure and delivery methodUS20100187283 *Jan 20, 2010Jul 29, 2010Lawrence CrainichMethod For Feeding Staples In a Low Profile Surgical StaplerUS20100187284 *Jan 20, 2010Jul 29, 2010Lawrence CrainichApparatus For Feeding Staples In a Low Profile Surgical StaplerUS20100191282 *Oct 29, 2009Jul 29, 2010Harris Jason LSurgical Stapler For Applying A Large Staple Through A Small Delivery Port And A Method of Using The Stapler To Secure A Tissue FoldUS20100191327 *Apr 5, 2010Jul 29, 2010Medtronic, Inc.Conformable prostheses for implanting two-piece heart valves and methods for using themUS20100249894 *Mar 3, 2010Sep 30, 2010Edwards Lifesciences CorporationProsthetic heart valve systemUS20100249908 *Mar 2, 2010Sep 30, 2010Edwards Lifesciences CorporationProsthetic heart valve system with positioning markersUS20100249920 *Jun 4, 2010Sep 30, 2010Millipede LlcReconfiguring heart featuresUS20100268253 *Apr 21, 2009Oct 21, 2010Sarah AhlbergSystem and method for closure of an internal opening in tissue, such as a trans-apical access openingUS20100312146 *Aug 17, 2010Dec 9, 2010Tyco Healthcare Group LpTissue tension detection systemUS20110054598 *Aug 9, 2010Mar 3, 2011Edwards Lifesciences CorporationContoured Sewing Ring for a Prosthetic Mitral Heart ValveUS20110098602 *Oct 27, 2009Apr 28, 2011Edwards Lifesciences CorporationApparatus and Method for Measuring Body OrificeUS20110125169 *Nov 19, 2010May 26, 2011Peter Karl JohanssonImplantable tissue structure modifiers and methods for using the sameUS20110125287 *Oct 28, 2010May 26, 2011Tyco Healthcare Group LP, New Haven CT and Confluent Surgical, Inc.Reinforced Tissue PatchUS20110174863 *Mar 28, 2011Jul 21, 2011Ethicon Endo-Surgery, Inc.Staple cartridges for forming staples having differing formed staple heightsUS20120061449 *Mar 11, 2010Mar 15, 2012Endogene Pty Ltd.Device and method for delivering shape-memory staplesUS20130331839 *Jun 8, 2012Dec 12, 2013Depuy Mitek, Inc.Surgical Fasteners and Methods and Devices for Deploying a Surgical FastenerUS20130338684 *Jul 26, 2013Dec 19, 2013Cardica, Inc.Mitral valve treatmentUS20140100652 *Dec 9, 2013Apr 10, 2014Medtronic, Inc.Attachment device and methods of using the sameUS20140171982 *Jul 24, 2012Jun 19, 2014Covidien LpSystems and methods for connecting tissue patchesUS20140222164 *Apr 4, 2014Aug 7, 2014Covidien LpReinforced Tissue PatchUS20140276830 *Mar 14, 2013Sep 18, 2014Daniel F. CheneyBone staples and methods of use therefor and manufacturing thereofUS20140276971 *Mar 12, 2014Sep 18, 2014St. Jude Medical, Cardiology Division, Inc.Mitral valve leaflet clipUS20150335432 *Feb 11, 2013Nov 26, 2015Osseous Technologies Of AmericaBiocompatible containment member for bone augmentation surgery made of processed natural membrane from an animal donorCN104173082A *Sep 11, 2014Dec 3, 2014王雯Wound closing deviceCN104703551A *Aug 8, 2013Jun 10, 2015W.L.戈尔及同仁股份有限公司Devices and methods for securing medical devices within an anatomyEP1986554A2 *Jan 30, 2007Nov 5, 2008The Children's Medical Center CorporationTissue tackEP1986554A4 *Jan 30, 2007Jan 4, 2012Childrens Medical CenterTissue tackEP2271270A1 *Apr 14, 2009Jan 12, 2011Boston Scientific Scimed, Inc.Endoscopic stapling device, related staples, and methods for useEP2271270A4 *Apr 14, 2009Mar 25, 2015Boston Scient Scimed IncEndoscopic stapling device, related staples, and methods for useEP2444008A3 *Aug 8, 2007Aug 29, 2012Ethicon Endo-Surgery, Inc.Surgical staples having compressible or crushable members for securing tissue therein and stapling instruments for deploying the sameWO2006135642A1 *Jun 7, 2006Dec 21, 2006Wilson-Cook Medical Inc.Medical staplerWO2007021834A1 *Aug 10, 2006Feb 22, 2007Guided Delivery Systems, Inc.Devices and methods for anchoring tissueWO2008039270A1 *Aug 8, 2007Apr 3, 2008Ethicon Endo-Surgery, Inc.Surgical staples having compressible or crushable members for securing tissue therein and stapling instruments for deploying the sameWO2008070486A2Nov 28, 2007Jun 12, 2008Wilson-Cook Medical Inc.Combination therapy hemostatic clipWO2008070486A3 *Nov 28, 2007Jul 31, 2008Gayzik Caroline MCombination therapy hemostatic clipWO2008089044A2 *Jan 10, 2008Jul 24, 2008The Trustees Of Columbia UniversityMitral valve repair deviceWO2008089044A3 *Jan 10, 2008Dec 24, 2008Wilmo C OrejolaMitral valve repair deviceWO2008094210A1Aug 8, 2007Aug 7, 2008Ethicon Endo-Surgery, Inc.Surgical staples and stapling instrumentsWO2008109087A1 *Mar 5, 2008Sep 12, 2008C2M Medical, Inc.Tack anchor systems, bone anchor systems,and method of useWO2009135022A1 *Apr 30, 2009Nov 5, 2009Ethicon Endo-Surgery, Inc.Clip and delivery assembly used in forming a tissue foldWO2010085725A1 *Jan 25, 2010Jul 29, 2010Ethicon Endo-Surgery, Inc.A surgical stapler for applying a large staple through a small delivery port and a method of using the stapler to secure a tissue foldWO2010085732A3 *Jan 25, 2010Oct 14, 2010Ethicon Endo-Surgery, Inc.A surgical stapler for applying a large staple through a small delivery port and a method of using the stapler to secure a tissue foldWO2010108079A1 *Mar 19, 2010Sep 23, 2010Millipede LlcReconfiguring heart featuresWO2011063288A2 *Nov 19, 2010May 26, 2011Peter Karl JohanssonImplantable tissue structure modifiers and methods for using the sameWO2011063288A3 *Nov 19, 2010Sep 15, 2011Peter Karl JohanssonImplantable tissue structure modifiers and methods for using the sameWO2016001382A3 *Jul 2, 2015Mar 17, 2016Medtentia International Ltd OyClip for a medical implant* Cited by examinerClassifications U.S. Classification606/221, 606/151, 606/213International ClassificationA61B17/064, A61B17/068, A61B17/122, A61B17/08Cooperative ClassificationY10S623/904, A61B17/083, A61B17/1227, A61B2017/0641, A61B17/064, A61B17/0682, A61F2/2427European ClassificationA61B17/064, A61B17/08C, A61B17/068BLegal EventsDateCodeEventDescriptionMar 5, 2004ASAssignmentOwner name: ARBOR SURGICAL TECHNOLOGIES, INC., CALIFORNIAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:DREWS, MICHAEL J.;GURSKIS, DONNLL W.;BACICH, STEVEN R.;REEL/FRAME:014403/0564Effective date: 20040304Feb 12, 2010ASAssignmentOwner name: MEDTRONIC, INC.,MINNESOTAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ARBOR SURGICAL TECHNOLOGIES, INC.;REEL/FRAME:023928/0383Effective date: 20100205Owner name: MEDTRONIC, INC., MINNESOTAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ARBOR SURGICAL TECHNOLOGIES, INC.;REEL/FRAME:023928/0383Effective date: 20100205Jan 7, 2013FPAYFee paymentYear of fee payment: 4Jul 9, 2014SULPSurcharge for late paymentRotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services