Source: http://www.patentgenius.com/patent/RE44638.html
Timestamp: 2018-06-18 09:49:46
Document Index: 726434253

Matched Legal Cases: ['art 1', 'Application No. 10163434', 'Application No. 0811654', 'Application No. 2003', 'Application No. 04', 'Application No. 01', 'Application No. 01', 'Application No. 01', 'Application No. 01', 'Application No. 02', 'Application No. 02', 'Application No. 02', 'Application No. 02', 'Application No. 02', 'Application No. 04', 'Application No. 05', 'Application No. 04']

Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta - Patent # RE44638 - PatentGenius
RE44638 Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
U.S. Class: 514/266.1; 544/277; 544/287
Field Of Search: ;514/266.1; ;544/277; ;544/287
Foreign Patent Documents: 0 525 960; 0 525 960; 0 525 960; 0 675 124; 0 675 124; 0 675 124; 0 716 857; 0 716 857; 0 716 857; 0 884 310; 0 884 310; 0 884 310; 0 900 568; 0 900 568; 0 900 568; 1356763; 1356763; 2 017 097; 2017097; 55-118917; 55 118917; 55-118918; 55 118918; 56-002322; 56 002322; WO-93/21259; WO-93/21259; WO-94/17090; WO-94/17090; WO-95/24379; WO-95/24379; WO-96/04923; WO-96/04923; WO-96/25488; WO-96/25488; WO-96/32478; WO-96/32478; WO-97/34631; WO-97/34631; WO-97/41097; WO-97/41097; WO-97/43276; WO-97/43276; WO-97/46688; WO-97/46688; WO-98/33802; WO-98/33802; WO-98/38173; WO-98/38173; WO-99/08501; WO-99/08501; WO-99/08501; WO-99/34804; WO-99/34804; WO-01/00881; WO-01/00881; WO-01/3076; WO-01/30768; WO-01/30768; WO-01/53266; WO-01/53266; WO-01/57034; WO-01/57034; WO-01/81346; WO-01/81346; WO-01/81346; WO-03/035075; WO-03/035075; WO-03/106622; WO-03/106622; WO-03/106622; WO-2004/007491; WO-2004/007491; WO-2004/012768; WO-2004/012768; WO-2004/026285; WO-2004/026285; WO-2004/026285; WO-2004/029055; WO-2004/029055; WO-2004/052373; WO-2004/052373; WO-2004/056820; WO-2004/056820; WO-2004/089925; WO-2004/089925; WO-2004/108708; WO-2004/108708; WO-2004/108709; WO-2004/108709; WO-2004/108713; WO-2004/108713; WO-2004-108713; WO-2004/108715; WO-2004/108715; WO-2004-108715; WO-2005/016348; WO-2005/016348; WO-2005/016349; WO-2005/016349; WO-2005/067901; WO-2005/067901; WO-2005-067901; WO-2005/120511; WO-2005/120511; WO-2009/058361; WO-2009/058361; WO-2010/065923; WO-2010/065923; WO-2010-065923; WO-2010/123931; WO-2010/123931
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Abstract: The invention provides a class of substituted quinazolinone compounds and methods of treating diseases mediated by PI3K.delta. activity. The disclosed compounds are useful in treating diseases such as bone-resorption disorders; and cancer, especially hematopoietic cancers, lymphomas, multiple myelomas and leukemia. The compounds are also useful in disrupting or inhibiting cellular processes such as leukocyte function or accumulation, neutrophils function, lymphocyte proliferation, and endogenous immune responses.
1. A compound of the formula: ##STR00183## .[.(S)-5-fluoro-3-phenyl-2-[1-(9H-purin-6-ylamino)-propyl]-3H-quinazolin-- 4-one,.]. or a pharmaceutically acceptable saltthereof.
2. A pharmaceutical composition comprising a compound according to claim 1 and at least one pharmaceutically acceptable excipient.
N,N'-(1-oxo-1,2-ethanediyl)-bis(aspartic acid), salts and use in detergent compositions
Air injection for nitrogen oxide reduction and improved product quality
Device for cleaning the guides of travelling flats in a flat carding machine
Fume hood sash sensing apparatus
Method and apparatus to change the operating frequency of system core logic to maximize system memory bandwidth
Method of stimulating cashmere growth on cashmere-producing goats using melatonin
Positive interlock for file cabinet