Source: https://oppex.com/environment/us/north-bethesda
Timestamp: 2018-01-18 06:02:01
Document Index: 339281883

Matched Legal Cases: ['art 13', 'art 13', 'art 2', 'art 13', 'art 12', 'art 12', 'art 13', 'art 13', 'art 13', 'art 6', 'art 6', 'art 12', 'art 13', 'art 12', 'art 12', 'art 13', 'art 13', 'art 13', 'art 6', 'art 12', 'art 13', 'art 13', 'art 12']

Public tenders for environment in North-bethesda United States
EnvironmentUnited Statesnorth-bethesda
Common Post Computing Environment.
United States, McCellan, CA - Other Defense Agencies, Office of the Secretary of Defense -
Other Defense Agencies, Office of the Secretary of Defense | Published May 5, 2015
Multi-paradigm Numerical Computing Environment Software
Other Defense Agencies, Defense Microelectronics Activity | Published December 2, 2015 - Deadline December 9, 2015
American Hospital Association Membership Renewal
THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICIATATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institutes of Health (NIH), Clinical Center (CC), Office of Purchasing and Contracts (OPC) ...
Department of Health and Human Services, National Institutes of Health | Published December 2, 2014 - Deadline December 9, 2014
THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICIATATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institutes of Health (NIH), Clinical Center (CC), Office of Purchasing and Contracts (OPC) intends to negotiate on a sole source basis with American Hospital Association (AHA), 155 N Wacker Dr, Suite 400 Chicago, IL 60606-1719, under the authority of 41 United States Code (U.S.C.) 253(c)(1) as set forth in Federal Acquisition Regulation (FAR) 6.302-1: Only one responsible source and no other supplies or services will satisfy agency requirements. The Clinical Center (CC) at the National Institutes of Health (NIH) has a requirement to maintain its membership with the AHA in order to remain informed on legislative, regulatory and judiciary changes that effect the health environment. The CC, NIH also has a need to be able to attend meetings regarding the development of policy as it pertains to the health environment and regulations that surround the health environment. This notice is not a request for competitive proposals. However, interested parties may identify their interest and capability in writing to Stacey Polk, spolk@cc.nih.gov within 7 calendar days of issuance of this notice. A determination by the Government not to compete this proposed contract action based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purposes of determining whether to conduct a competitive procurement.
Department of Health and Human Services, National Institutes of Health | Published August 13, 2015 - Deadline August 24, 2015
INTRODUCTION This is a combined synopsis/solicitation for commercial items. This announcement constitutes the only solicitation; quotations are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13 - Simplified Acquisition Procedures in combination with FAR 12.6 Streamlined Procedures for Evaluation and Solicitation for Commercial Items. The solicitation number is HHS-NIH-NIDA-SSSA-CSS-15-757 and the solicitation is issued as a request for quotation (RFQ). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 541519 with a Size Standard of $27.5 Million. SET-ASIDE STATUS This acquisition is 100% set-aside for small businesses. ACQUISITION AUTHORITY This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures. This acquisition is NOT expected to exceed the simplified acquisition threshold. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-83, dated July 2, 2015. The resultant purchase order will include all applicable provisions and clauses in effect through this date. DESCRIPTION OF REQUIREMENT Purpose The Computational Chemistry staff of the National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) requires (specialized and highly skilled installation, configuration and IT support of newly procured computational equipment. For this project, the major objectives will be as follows: 1.	Install the computational environment hardware by racking, cabling, installing, and configuring all purchased hardware, including any integration with NIH systems as required 2.	Configure the system for FISMA server certification and security compliance operations in accordance with NIH policies 3.	Provide detailed start-up support for the environment, including software and operational support for two (2) weeks following the initial installation of the systems 4.	Provide limited long-term support of the computational environment for a period of one year. Project Requirements In order to begin this computational research at NIDA, the IRP Computational Chemist will require a dedicated computational infrastructure including specialized hardware and configurations that will interface with the laboratory's software stack at efficient speeds to effectively model the molecular interactions between small molecules and membrane-bound proteins. The hardware will require highly skilled expertise to construct, configure, and support in this scientific environment. The NIDA IRP requires a firm to provide specific expertise in the construction, configuration, and support of high performance computational equipment in computational chemistry environments. Specifically, •	Designate adequate number of consultants for the efficient progress of the project; •	Travel to Baltimore, MD to work onsite at NIDA to o	build and configure the GPU-dense infrastructure purchases made by NIDA IRP, and to integrate them with existing NIH networks, authentication systems, security policies, and certification procedures o	Tune the backup systems, implement the monitoring system, and carry out onsite training on maintenance; o	Configure the cluster to run the GPU versions of molecular simulation programs Desmond and NAMD. •	Provide full documentation of the newly installed systems and the respective configurations and development of how-tos; •	Provide ongoing low-level systems support of the computational infrastructure o	Provide support at no more than 3 hours/week for the maintenance of the established infrastructure; o	Track progress, effort, and milestones in a secured extranet project management site accessible by the NIDA IRP staff. Anticipated Period of Performance The period of performance for this requirement is 12 months after receipt of award. Contract Type The Government intends to issue a firm fixed price purchase order for this requirement. APPLICABLE CLAUSES AND PROVISIONS All Offerors MUST be actively registered in the System for Award Management (SAM) www.sam.gov. The provision at FAR clause 52.213-4, Terms and Conditions - Simplified Acquisitions, applies to this acquisition. The applicable Information Security clauses are attached. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. EVALUATION CRITERIA The Government will award a purchase order resulting from this solicitation on the basis of lowest price technically acceptable. Technical acceptability will be evaluated based upon the following: 1.	Factor 1: Technical Approach The Offeror shall demonstrate an in depth knowledge and experience about the tasks as described in the project requirements. 2.	Factor 2: Staffing Plan The Offeror shall propose a staffing plan based upon the tasks outlined in the project requirements. Offeror's must provide a narrative detailing the rationale for labor categories and quantity of staff proposed. RESPONSE FORMAT Responses to this solicitation must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the technical evaluation criteria. The price quotation must include the requirements listed above as well as associated pricing. Contractors must provide their Company Name, Dun & Bradstreet Number (DUNS), Taxpayer Identification Number (TIN), Business Size, Physical Address, and Point of Contact Information in their responses. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." CLOSING STATEMENT All responses must be received by the closing date of this announcement and must reference solicitation number HHS-NIH-NIDA-SSSA-CSS-15-757. Responses shall be submitted electronically via email to Megan Ault, Contract Specialist, at megan.ault@nih.gov.
Point of Sale (POS) System at NIH
THIS IS A NOTICE OF INTENT, NOT A SOLICITATION FOR COMPETITIVE PROPOSALS. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institutes of Health (NIH) intends to negotiate on a sole source basis wi ...
Department of Health and Human Services, National Institutes of Health | Published August 24, 2016 - Deadline August 30, 2016
THIS IS A NOTICE OF INTENT, NOT A SOLICITATION FOR COMPETITIVE PROPOSALS. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institutes of Health (NIH) intends to negotiate on a sole source basis with Agilysys NV, LLC, 1000 Windward Concourse, Suite 250, Alpharetta, GA 30005 to procure and install a new Point of Sale (POS) system for its retail food service operations on its Bethesda Campus. No solicitation exists for this requirement. The proposed contract action is for services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 6.302. The product is a commercial item as defined in FAR Part 2.101. The period of performance shall be for one twelve (12) months base period, with options to renew for four (4) successive twelve month periods. It is believed that Agilysys NV, LLC is the sole source for this requirement under the authority of U.S.C. 253(c)(1) as set forth in the Federal Acquisitions Regulation (FAR) 6.302-1 "Only one responsible source and no other supplies and services will satisfy agency requirements" because of the following: Agilysys NV, LLC is the only known source that meets all the criteria; which includes meeting all the security, training and support requirements as outlined in the statement of work. Below is the Draft Statement of Work. This is NOT A SOLICITATION FOR COMPETIVE PROPOSALS. Interested parties may identify their interest and capability to respond to the requirement or submit proposals which demonstrates their ability to supply the services described below. The capability statement and any other information furnished must be in writing, and must contain material in sufficient detail to allow the Government to determine if the party can meet all of the requirements of the Statement of Work. Capability Statements and related materials must be received by the Contract Specialist, no later than August 30, 2016 at 10:00 A.M. Eastern Time. Written responses received after this date and time will not be accepted. A determination by the Government not to compete this proposed contract based on the responses received is solely within the discretion of the government. The information received will be considered solely for the purpose of whether to conduct a competitive procurement. Address responses via email only to the attention of: O. Joy Ajao, The National Institutes of Health, OLAO, Office of Acquisitions, email address: ajaooj@mail.nih.gov DRAFT STATEMENT OF WORK PROJECT TITLE: Point of Sale (POS) System at NIH The National Institutes of Health is planning on acquiring a point of sale system for its retail food service operations on its Bethesda Campus. The point of sale system must meet the following criteria:• PCI DSS compliant• By January 1, 2017 be PCI QIR compliant• Fedramp & FISMA compliant• May be hosted in house in virtual server environment• Open access platform software• Nonproprietary hardware platform• Ability to integrate multiple peripherals including scales, printers, credit card swipes, bar code scanners, proximity readers, and change cartridges• Integrated order and self-checkout kiosk system• Back of the house analytics package to provide analysis by profit center and roll up to campus wide, of sales and transaction system to determine productivity, profit contribution, cash control, audit records, time management, item detail reports, and trend analysis with a minimum 13 month history on line.• Analytics must be able to provide inventory tracking and ordering integration• Minimum ability to handle 24 terminals in 7 profit centers with the ability to expand to cover 60+ stations and 11 profit centers• Ability to securely compartmentalize operators/ profit centers if multiple vendors are using the system• Hardware support and resolution with no more than 24 hours turnaround• Software support available 24/7 M-F• System must run on Microsoft 2008 and 2010 within 14 months• Onsite installation and training of all users, super users and in house IT professionals• Onsite support for testing and "go live" trouble shooting for 7 profit centers located on a 320 acre campus Other Important Considerations: Security Requirements• System meets the Security Assessment and Authorization (SA&A), in compliance with FISMA requirements.• System is capable on inheriting the controls of the existing Application Hosting Environment (AHE), i.e. system can be run in a virtual environment VMWARE and runs Microsoft SQL.• System complies with Payment Card Industry (PCI) Standards.• System complies with NIH login requirements, i.e. able to integrate with Siteminder.• System is compatible with Windows USGCB configuration setting: http://usgcb.nist.gov/usgcb_faq.html.• System utilizes a secure environment to process credit cards and debit card transactions.• System DOES NOT store credit card data. Training and Support Requirements • System comes with a help menu and a reference guide that explains functionality.• System provides a help menu or reference guide that explains how costs should be allocated.• "System's user documentation describes the following: o Application setup requirementso How to get startedo How to recover from "error messages"• Vendor is able to provide the end-users with an accurate Data Dictionary and Entity Relationship (ER) Diagram upon request. The diagram and data dictionary must be updated with each new maintenance release.• Vendor will provide on-site end-user training that is tailored to NIH user groups and their tasks.• Vendor will provide on-site administrator training that is tailored to NIH user groups and their tasks.• Vendor will provide training on any changes or upgrades that are done to System
Analyzing social media data/machine learning approach
Department of Health and Human Services, National Institutes of Health | Published February 8, 2016 - Deadline February 22, 2016
This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation number is NICHD-16-021 and is issued as a Request for Quotation (RFQ). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2005-86. The North American Industry Classification (NAICS) Code is 518210 and the business size standard is $32.5m. However, this solicitation is not set aside for small business. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part 13. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) intend to procure on a sole source basis with SecondHelix of Alexandria, VA to tailored keyword searches on social media and content analysis on the social media data using a machine learning approach. The begin date of service will be on or around March 1, 2016 for a performance period of five months from begin date and vendor location is the place of performance. See Attached S.O.W.Specifically, SecondHelix will use keyword searched such as smoking and tobacco for relevant tweets during January 1, 2009 through October 15, 2015. SecondHelix will download all the relevant tweets related to the research topic. SecondHelix will randomly sample some percent of the tweets (depending on the total number of tweets), review them and develop a coding scheme to classify these tweets in different themes and subthemes. SecondHelix will then write a computer-based algorithm so that a computer can do the classification. SecondHelix will randomly sample a percent of tweets to see if the algorithm is correct and sensitive. If algorithm is not correct and sensitive then SecondHelix will revise the algorithm, however if correct a computer will do all the subsequent coding. SecondHelix is the only known source available that fit the needs of the lab. SecondHelix offers tailored keywords searches on social media and content analysis on the social media data using a machine learning approach, which enable the lab to analyze millions of social media data points. In addition, SecondHelix unique expertise in managing and analyzing Twitter data and their ability to integrate geographical data into the Twitter data is vital to the lab research requirements. Also, SecondHelix offers the service to integrate social media data with geographical information, which is essential to the lab research. SecondHelix specific experience and knowledge in this area are critical to the lab research initiative. The lab wants to understand the social discussions about tobacco and its disparities because these discussions shape public opinions and perceptions. In the past (prior to social media) it was impossible to capture these discussions in large scales, now with social media the lab can acquire this information. It is essential to examine social media because behavioral theories post that social environment is influential to individuals behaviors. The lab wants to understand how the public discuss tobacco and its disparities. The insight to be gain can help us better understand the social environment and guide the lab in examining whether the public discussions need to be changed to create a more supportive environment for disadvantaged smokers to quit smoking, which is the research goal of the lab.The proposed contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under authority of the 41 U.S.C. 253(c) (1), FAR 6.302. Only one responsible source and no other supplies or services will satisfy agency requirements. The offeror must include a completed copy of the provision of FAR Clause 52.212-3, Offeror Representations and Certifications - Commercial Items with its offer. The provisions of FAR Clause 52.212-1 Instructions to Offerors - Commercial Items; FAR Clause 52.212-2, Evaluation - Commercial Items; FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items; and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items - Deviation for Simplified Acquisitions applies to this acquisition. The offeror must include their Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. The clauses are available in full text at http://www.acquisition.gov/far/. Interested vendors capable of furnishing the government with the services specified in this synopsis should submit a copy of their quotation to the below address or via email to robinsti@mail.nih.gov. Offers must also be accompanied by descriptive literature, delivery timeframe, warranties and/or other information that demonstrates that the offer meets all of the foregoing requirements. Quotations will be due fifteen calendar days from the publication date of this synopsis or by February 22, 2016 by 10 am, EST. via email or postal mail. The quotation must reference "Solicitation number" NICHD-16-021. Quotations sent by postal mail or other mailing services must be submitted to the following address: Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Boulevard, Room 5C01, Bethesda, MD 20852. Attention: Tina Robinson, by the date and time mentioned above. Any questions must be sent via email to robinsti@mail.nih.gov and must include solicitation# NICHD-16-021 in the subject line of email. Faxed copies/responses will not be accepted. Note: In order to receive an award, contractor must be registered for all awards and have valid/current certification in the SAM database @www.sam.gov.
Native American Lands Environmental Mitigation Program (NALEMP) Technical Support
The United States Army Corps of Engineers (USACE) is the executing agency responsible to the Office of the Deputy Under Secretary of Defense (Installations & Environment (ODUSD(I&E)) for executionof the NALEMP program through Cooper ...
Department of the Army, U.S. Army Corps of Engineers | Published August 30, 2016
The United States Army Corps of Engineers (USACE) is the executing agency responsible to the Office of the Deputy Under Secretary of Defense (Installations & Environment (ODUSD(I&E)) for executionof the NALEMP program through Cooperative Agreements with tribal governments within New Mexico. The USACE Albuquerque District is the Department of Defense's (DoD's) lead organization for addressing NativeAmerican issues in New Mexico. The contractor will provide technical, field level, and logistical support on nine (9) NALEMP Cooperative Agreements (CA), in support of addressing DoD related environmental impacts on Native American lands.
NIH/RML Library Renovation Project
The Rocky Mountain Laboratory (RML) requires a remodel of the existing Library in Building A. Building A is housed in the historical "Quad" which consists of Buildings A, 1, 2, 3, 5, 6 and 7. The Quad is a red brick Neoclassic aca ...
Department of Health and Human Services, National Institutes of Health | Published September 10, 2015
The Rocky Mountain Laboratory (RML) requires a remodel of the existing Library in Building A. Building A is housed in the historical "Quad" which consists of Buildings A, 1, 2, 3, 5, 6 and 7. The Quad is a red brick Neoclassic academic style complex of research occupied buildings. The third floor area to be refurbished is approximately 3,940 sf. requires a general modernization from the original 1996 construction. The mission of this Design/Build contract is to accomplish general upgrades, adding in a few key spaces and features, and general rearrangement of work space. Design Objectives include: 1. To use the latest technology to foster collaboration and innovation 2. To design a comfortable, quiet and collaborative working environment for all RML staff 3. To design a number of architectural impact features that draw the RML staff into the new library 4. To create a library that can grow into future needs 5. To bring in as much natural light as possible into the library. This will be accomplished while minimizing the duration and impact of the construction activities to the NIAID program. The mechanical/electrical design philosophy is to rework the existing mechanical system, provide general power, lighting and system adjustments to support the rearrangement. The architectural "impact" features to draw the library patrons into the newly remodeled area include masonry & glass exterior cantilever window area which will include miscellaneous and structural steel. Interior remodel area will include hollow metal doors, metal stud gypsum walls, joint sealants, painting, glass walls, miscellaneous specialties, sound panels, casework, fire sprinkler system adjustments, plumbing/HVAC, BAS upgrades and electrical lighting.
ACEA Biosciences xCELLigence Real Time Cell Analyzer-DP Bundle
(1) Action Code: Combined Synopsis/Solicitation (2) Date: August 24th, 2015 (3) Year: 2015 (4) Contracting Office Zip Code: 20892 (5) Classification Code: 6640 (6) Contracting Office Address: 6701 Rockledge Drive Rockledge II Bethesda, MD 2 ...
Department of Health and Human Services, National Institutes of Health | Published August 24, 2015 - Deadline August 31, 2015
(1) Action Code: Combined Synopsis/Solicitation (2) Date: August 24th, 2015 (3) Year: 2015 (4) Contracting Office Zip Code: 20892 (5) Classification Code: 6640 (6) Contracting Office Address: 6701 Rockledge Drive Rockledge II Bethesda, MD 20892 (7) Subject/Title: ACEA Biosciences xCELLigence Real Time Cell Analyzer-DP Bundle (8) Proposed Solicitation Number: NHLBI-CSB-DE-2015-216-KEW (9) Closing Response Date: August 31st, 2015 (10) Contact Point: Kyle Wisor, Contract Specialist (11) Contract Award and Solicitation Number: TBD (12) Contract Award Dollar Amount: UKN (13) Contract Line Item Number(s): Line Item 1: xCELLigence RTCA-DP Bundle; Line Item 2: Shipping (14) Contractor Award Date: September 9th, 2015 (15) Contractor Name: TBD (16) Description: The National Institutes of Health (NIH), National Institute of Dental and Craniofacial Research (NIDCR), Oral Pharyngeal Cancer Branch (OPCB) is researching therapies for tumor treatments. A tumor vaccine is the one of the most promising therapies for tumor treatment among multiple methods of immunotherapy. The vaccine would activate the tumor-specific immunity without affecting the normal tissues. However, the tumor immunity induced by the tumor vaccine may undergo a process called tumor editing in the tumor microenvironment, where the tumor cells may escape the effects of the vaccine, resulting in low immunogenicity, especially in solid tumors. The regulatory T cell (Treg, a type of white blood cell) is one of the important mechanisms by which tumor editing occurs, and these cells can suppress the immune system by directly contacting tumor-specific cytotoxic T cells or through producing proteins called cytokines. Therefore, inhibiting the functions of Treg cells during tumor vaccine treatment may be the solution to increasing the efficiency of tumor-specific immunity. The NIDCR OPCB requires an ACEA xCELLigence RTCA-DP Bundle to help the labs tumor assays and other adherent cell experiments. (i) "This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued." (ii) The solicitation number is NHLBI-CSB-DE-2015-216-KEW and the solicitation is issued as a request for quote (RFQ). (iii) The solicitation document, the incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-83 effective 03 AUG 2015. (iv) This is a small business set aside. The associated NAICS code is 334118, Computer Terminal and Other Computer Peripheral Equipment Manufacturing, and the small business size standard is 1000 Employees. The acquisition is being conducted in accordance with the procedures of FAR Part 12 and FAR Part 13. (v) The Contractor Requirements are listed below: (vi) The Contractor Shall: 1. The contractor shall provide the ACEA Biosciences xCELLigence RTCA (Real-time Cell Analyzer)-DP Bundle, product number 00380601050, Quantity 1. I. Specifications • RTCA DP Plate Station and Analyzer o Electrical input: +6V DC, 5 W max o Electronic switch resistance: 2-5 ohm o Electrical interface: handling three E-Plate® 16 devices or 3 IM-Plate devices o Communications: RS232 serial communications at a band rate of 57600 bits/second o Environment: 15° C to 40° C, relative humidity: 98% max non-condensing o Output test signal: 22mV rms ± (2% +5 mVrms) @ 10, 25 and 50 kHz o Impedance measure accuracy: ± (2% + 1.5 ohm) o Impedance measurement repeatability: 0.5% o Impedance dynamic range: 5 ohm to 2 kohm o Environment: 5° C to 40° C, Relative humidity: 80% max. up to 31° C decreasing linearly to 50% max at 40° C • RTCA DP Software o User friendly GUI (Graphical User Interface) o Flexible experimental protocol setup o Real-time data acquisition o Real-time numeric and graphic data display o Multiple output formats • RTCA DP WorkStation o Laptop computer capable of running RTCA DP Software (vii) Date of Delivery: Ship upon receipt of the order Place of Delivery: National Institute of Health, NIDCR 30 Convent Drive Building 30, Room 310 Bethesda, MD 20892 (viii) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. (ix) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, is applicable. The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: Contract award shall be made to the responsible Offeror whose offer, in conforming to this RFQ, provides the overall best value to the Government, technical evaluation factors, and cost considered. The Government's objective is to obtain the highest technical quality considered necessary to achieve the project objectives, with a realistic and reasonable cost. Technical evaluation factors are more important than cost. 1: Technical Criteria (90 points) I. The contractor will be evaluated on the product provided meeting the below specifications: • RTCA DP Plate Station and Analyzer o Electrical input: +6V DC, 5 W max o Electronic switch resistance: 2-5 ohm o Electrical interface: handling three E-Plate® 16 devices or 3 IM-Plate devices o Communications: RS232 serial communications at a band rate of 57600 bits/second o Environment: 15° C to 40° C, relative humidity: 98% max non-condensing o Output test signal: 22mV rms ± (2% +5 mVrms) @ 10, 25 and 50 kHz o Impedance measure accuracy: ± (2% + 1.5 ohm) o Impedance measurement repeatability: 0.5% o Impedance dynamic range: 5 ohm to 2 kohm o Environment: 5° C to 40° C, Relative humidity: 80% max. up to 31° C decreasing linearly to 50% max at 40° C • RTCA DP Software o User friendly GUI (Graphical User Interface) o Flexible experimental protocol setup o Real-time data acquisition o Real-time numeric and graphic data display o Multiple output formats • RTCA DP WorkStation o Laptop computer capable of running RTCA DP Software 2: Price Criteria (10 points) • Price reasonableness: Best Value (x) FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, is applicable. An offeror shall complete only paragraphs (b) of this provision if the offeror has completed the annual representations and certificates electronically via http://www.acquisition.gov. If an offeror has not completed the annual representations and certifications electronically at the System for Award Management (SAM) website, the offeror shall complete only paragraphs (c) through (p) of this provision. (xi) FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. (xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items, applies to this acquisition. Including the following clauses and Prohibitions: i. 52.223-18, Encouraging Contractor Policies to Ban Text Messaging while Driving (AUG 2011) ii. 52.225-13, Restrictions on Certain Foreign Purchases iii. 52.244-6, Subcontracts for Commercial Items iv. 52.2232-39, Unenforceability of Unauthorized Obligations v. 52.219-6, Notice of Total Small Business Set-Aside vi. 52.222-3, Convict Labor vii. 52.222-19, Child Labor--Cooperation with Authorities and Remedies viii. 52.222-26, Equal Opportunity ix. 52.222-35, Equal Opportunity for Veterans x. 52.222-36, Equal Opportunity for Workers with Disabilities xi. 52.222-37, Employment Reports on Veterans xii. 52.222-50 Combating Trafficking in Persons xiii. 52.232-33, Payment by Electronic Funds Transfer-System for Award Management xiv. 52.222-21, Prohibition of Segregated Facilities (xiii) Additional Contract Requirements: None (xiv) The Defense Priorities and Allocations System (DPAS) and assigned rating are not applicable. (xv) All responses must be received by August 31st, 2015 at 9:00 AM and must reference number NHLBI-CSB-DE-2015-216-KEW. Responses may be submitted electronically to Kyle.Wisor@nih.gov or by U.S. mail to the National Heart, Lung, and Blood Institute, Office of Acquisitions, COAC Services Branch, 6701 Rockledge Drive, Suite 6150B, Bethesda, MD 20892-7902, Attention: Kyle Wisor. Phone: 301-402-3670; Fax responses will not be accepted
Steri-Cult 3310 Incubators
This is a notice of intent, not a request for a quotation. A solicitation document will not be issued and quotations will not be requested.The Government intends to award a fixed price purchase order to Thermo Fisher Scientific, Hanover Par ...
Department of Health and Human Services, National Institutes of Health | Published November 22, 2017 - Deadline December 6, 2017
This is a notice of intent, not a request for a quotation. A solicitation document will not be issued and quotations will not be requested.The Government intends to award a fixed price purchase order to Thermo Fisher Scientific, Hanover Park, IL.The Department of Transfusion (DTM) at the National Institutes of Health (NIHCC), Cell Processing Section (CPS) Bethesda, MD has a requirement to procure the services listed below: The DTM is a unique blood center which collects blood and blood components from healthy donors to patients participating in many protocols. Numerous regulatory authorities, specifically the Food and Drug Administration (FDA) and American Association of Blood Bank (AABB) set policy and enforce this policy for care and maintenance of equipment that is used in support of donors and patients per the above. The CPS requires that these 20 incubators, used for patient cell culturing, are placed under a Service Agreement and the Manufacturer has the trained experts and exact specifications so this may function properly for patient care. Primary services sought:Quantity: 16 eachCatalog: Total CareDescription: 01-Steri-Cult 3310 incubators: 310425-866; 310425-867; 311486-953; 311486-954; 311485-950; 311485-951; 314838-1136; 314838-1137; 315931-1207; 318023-1274; 318024-1279; 392925-1538; 392925-1537. Quantity: 4 eachCatalog: Total CareDescription: Total Care for HERAcell 150i SST Incubators: 41129838; 41128940; 41034482; 41034909. Quantity: 20 eachCatalog: Total CareDescription: Total care for Steri-Cult 3307 models: 300052614; 300056002; 300054626; 300052619; 300054624; 300053532; 300056000; 300052616; 300054633; 300054625, 300054631; 300054621; 300054627; 300052615; 300052618; 300001407; 300054622, 300054632; 300054623; 300054630. Quantity: 8 eachCatalog: PMDescription: Total Care for Hera Vios 160i CO2 42111196; 42100620; 42094217; 42111205; 42100607; 42106202; 42106201; 42100619. The service agreement is to provide annual yet scheduled preventative maintenance and it covers maintenance and associated repair costs. The incubators control the external environment for cells to grow X-VIVO. There is no other known company that can provide the breadth and depth of knowledge to properly service this specialized. This company has the trained experts to provide maintenance and service under this agreement and provides the proper documentation for regulatory purposes as is required for our facility which is FDA licensed and AABB regulated.
Sj�gren�s Syndrome Mouse Study
INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION. The National Heart, Lung, and Blood Institute (NHLBI), Office of Acquisitions (OA) ...
Department of Health and Human Services, National Institutes of Health | Published July 5, 2016 - Deadline July 15, 2016
INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION. The National Heart, Lung, and Blood Institute (NHLBI), Office of Acquisitions (OA), intends to negotiate and award a purchase order on a noncompetitive sole source basis to the University of Florida, 207 Grinter Hall, Gainesville, FL, 32611-0001, to breed, house, and test the salivary gland activity in NOD derived C57BL/6.NOD-Aec1/Aec2 mice BACKGROUND The Molecular Physiology and Therapeutics Branch (MPTB) pursues a comprehensive bench-to-bedside program to understand the molecular basis of salivary gland function and dysfunction and to develop strategies for the diagnosis, prevention, and management of salivary gland diseases. Primary Sjögren's Syndrome (pSS) is a systemic autoimmune disorder characterized by exocrine gland dysfunction primarily involving the salivary and lacrimal gland. The histologic hallmark of Sjögren's Syndrome is a periductal inflammatory infiltrate. The conventional explanation of salivary gland (SG) dysfunction assumes a causal relationship between this chronic inflammatory process and the decreased saliva production. However, most patients have preserved salivary gland tissue and in overall the correlation between the focus score on SG biopsy (a measure of inflammation) and saliva production is limited. Recent studies have suggested that some immunomodulatory proteins may have beneficial effects in animal models of the disease and warrant further testing. PURPOSE The purpose of this acquisition is to procure the services of a Contractor to breed, house, and test the salivary gland activity in NOD derived C57BL/6.NOD-Aec1/Aec2 mice, a unique population of mice that are prone to the development of a Sjögren's Syndrome-like disease. The work to be performed is directly related to the mission of the MPTB, and is necessary in order to expand upon current studies in patients suffering from Sjögren's Syndrome. This particular strain of mice has been designed to develop disease with a high rate of penetrance. The MPTB was unable to achieve this result in several attempts in-house, and is thus requesting the support of an outside Contractor. PROCUREMENT The contractor shall perform the following tasks: •	Breed mice to yield 118 mice for the study•	House mice for 266 days•	Collect and measure saliva flow activity every 4 weeks for approximately 38 weeks.•	Collect and measure lacrimal gland activity every 4 weeks for approximately 38 weeks.•	After the last saliva collection, the mice will be euthanized, and blood and tissues will be collected. Blood, tissue, and saliva samples will be sent back to the MPTB for analysis. JUSTIFICATION The sole source determination is based on the fact that through our extensive market research, the University of Florida was the only vendor we were able to identify as having the capability to meet the need of the Government. The University has performed extensive work over the past several years to establish the correct environment for these particular mice to develop disease with a high rate of penetrance. In addition to an unacceptable time delay, the financial commitment required to establish a similar research environment elsewhere would be cost-prohibitive to the Government. REGULATORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b), soliciting from a single source (for purchases not exceeding the simplified acquisition threshold) and only one responsible source and no other supplies or services will satisfy agency requirements. ADDITIONAL INFORMATION Industry Classification (NAICS) Code is 541690, Other Scientific and Technical Consulting Services, and the Small Business Size Standard is $15.0M. The acquisition is being conducted under FAR Part 13, Simplified Acquisition Procedures, therefore the requirements of FAR Part 6, Competitive Requirements, are not applicable (FAR Part 6.001). The resultant award will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-88 (June 15th, 2016). This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by July 15, 2016 at 9:00AM EST and must reference synopsis number NHLBI-CSB-(HL)-2016-201-KMA. Responses shall be submitted to the National Heart, Lung, and Blood Institute, Office of Acquisitions, COAC Services Branch, 6701 Rockledge Drive, Room 6127, Bethesda, Maryland 20892-7902, Attention: Kevin Alvarez. Responses may be submitted electronically to kevin.alvarez@nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."
Upgrade EMC ApplicationXtender System
National Institutes of Health/Office of Extramural Research/Office of Research Information Systems/electronic Research AdministrationStatement of WorkFebruary 23, 2016Upgrade EMC ApplicationXtender SystemScope:The National Institutes of Hea ...
Department of Health and Human Services, National Institutes of Health | Published February 23, 2016
National Institutes of Health/Office of Extramural Research/Office of Research Information Systems/electronic Research AdministrationStatement of WorkFebruary 23, 2016Upgrade EMC ApplicationXtender SystemScope:The National Institutes of Health, Office of the Director, Office of Extramural Research, Office of Research Information Systems/electronic Research Administration has a requirement for the purchase of services to upgrade EMC ApplicationXtender system to new version. This is a combined synopsis/solicitation (RFQ) for commercial items in accordance with the format under Simplified Acquisition Procedures at Federal Acquisition Regulation (FAR) Subpart 12.603, supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. This solicitation document incorporates provisions and clauses that are in effect in the March 2005 Federal Acquisition Regulation (FAR) Revision, including all FAR Circulars issued as of the date of this synopsis. It is the intent of The National Institutes of Health, Office of the Director/Office of Research Information Systems to purchase upgrade for the EMC ApplicationXtender system to the new version. Contractor Requirements:Provide as follows: Manufacturer Description Vendor will backup environmentVendor will migrate the existing Oracle database to a new server provided by OER/ORIS/eRA/Operation BranchVendor will migrate the image to the new serverVendor will provide environment documentation and a current state analysis document at project closureVendor will upgrade the EMC ApplicationXtender to version 8 (software upgrades will be provided under existing separate maintenance contract)Vendor will install and configure the applications on the new servers (AX, WX, Web services, Retention Manager, Xplore)Vendor will test the migrated system and confirm successful migrationVendor will provide training documentation on the client upgrade proceduresVendor will project project management, analysis, deployment and post-deployment supportAll work will be done through remote methods Period of Performance: This requirement will be a base year of 12 months.Award will be made to the vendor based on lowest price technically accepted (LPTA). Contract Type:This requirement is fixed price.508 ComplianceSoftware must comply with the Section 508 (29 U.S.C. ‘794 d).Software must comply with the Section 508 (29 U.S.C. ‘794 d). Please provide statement on quote that software is 508 compliant. Please provide a copy of the software license with the quote. The Section 508 standards applicable to this contract/order are identified below:a. A text equivalent for every non-text element shall be provided (e.g., via "alt", "longdesc", or in element content).b. Documents shall be organized so they are readable without requiring an associated style sheet.c. Row and column headers shall be identified for data tables.d. Pages shall be designed to avoid causing the screen to flicker with a frequency greater than 2 Hz and lower than 55 Hz.e. A text-only page, with equivalent information or functionality, shall be provided to make a web site comply with the provisions of this part, when compliance cannot be accomplished in any other way. The content of the text-only page shall be updated whenever the primary page changes.f. When pages utilize scripting languages to display content, or to create interface elements, the information provided by the script shall be identified with functional text that can be read by Assistive Technology.g. When a web page requires that an applet, plug-in or other application be present on the client system to interpret page content, the page must provide a link to a plug-in or applet that complies with 1194.21(a) through (l).h. When electronic forms are designed to be completed on-line, the form shall allow people using Assistive Technology to access the information, field elements, and functionality required for completion and submission of the form, including all directions and cues.i. A method shall be provided that permits users to skip repetitive navigation links. Authority: 29 U.S.C. 794d. The contractor must provide a written Section 508 conformance certification due at the end of each order/contract exceeding $100,000 when the order/contract duration is one year or less. If it is determined by the Government that EIT products and services provided by the Contractor do not conform to the described accessibility in the Product Assessment Template, remediation of the products and/or services to the level of conformance specified in the vendor's Product Assessment Template will be the responsibility of the Contractor at its own expense.In the event of a modification(s) to the contract/order, which adds new EIT products and services or revised the type of, or specifications for, products and services the Contractor is to provide, including EIT deliverables such as electronic documents and reports, the Contracting Officer may require that the contractor submit a completed HHS Section 508 Product Assessment Template to assist the Government in determining that the EIT products and services support Section 508 accessibility requirements. Instructions for documenting accessibility via the HHS Section 508 Product Assessment Template may be found at http://508.hhs.gov.Only electronic copies of quotes will be accepted and should be emailed to briscoee@mail.nih.gov. The e-mail shall contain the following subject line: NIH-LM-2016751 - Upgrade EMC ApplicationXtender System. Please submit all information to Em'Ria J. Briscoe at briscoee@mail.nih.gov by March 2, 2016. NO TELEPHONE REQUESTS WILL BE ACCEPTED.
MONITORING/MAINT. AQUATIC FAC. EQUIPMENT/SYS.
Department of Health and Human Services, National Institutes of Health | Published December 4, 2015 - Deadline December 14, 2015
This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation number is NICHD-16-008 and is issued as a Request for Quotation (RFQ). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2005-84. The North American Industry Classification (NAICS) Code is 811219 and the business size standard is $19m. However, this solicitation is not set aside for small business. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part 13. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) intend to procure on a sole source basis with Siemens Industry, Inc. - 6435 Virginia Manor Road - Beltsville, MD a one year preventative maintenance agreement for remote monitoring services of equipment/components and software services (in a scientific environment) for the animal facilities (Bldgs. 6B, 32T and 10 across the NIH campus) and all aquatic facilities across the NIH main campus in Bethesda, MD. Equipment and software to be maintained and monitored: Equipment: Quantity: Serial/MDL Modems	3 EACH	3061 Monitor	1 EACH	4112 PC Workstations	2 EACH	4119 Dot Matrix Printer	1 EACH	4115 Apogee Ethernet Modules	3 EACH Digital Point Unit	1 EACH	3028 Modular Building Controller	1 EACH	3382 Pump Control Relays	13 EACH	3137 Sump Level Sensors	5 EACH	3121 Immersed Temperature Sensors	9 EACH	3036 AOP Transducers	2 EACH	3043 Control Valves	2 EACH	3124 Solenoid Valves	4 EACH	3123 Mechanical Equipment Controllers	6 EACH	3528 Mechanical Equipment Controllers Point Blocks	5 EACH	3529 Apogee Software	1 EACH	3516 InfoCenter Software	1 EACH Uninterruptable Power Supplies	5 EACH	9901 Local User Interfaces Panels 1 EACH	9902 Services to Include (not limited to) The software services to include: (1)	Annual software updates (2)	Annual documentation updates (3)	Graphics creation (4)	Graphics backup (5)	Field Panel Database/System File Backup (6)	Control Loop Evaluation and Tuning (7)	Software Consultation The System Performance Services to include: (1)	On-line troubleshooting (2)	Operator support (3)	System Preventive Maintenance (4)	Corrective Maintenance and Component Replacement (5)	Account Management Emergency Service Options to include: (1)	Response Window - Provide emergency services between scheduled preventative maintenance calls. (2)	On-Line Response (3)	On-Site Response Documentation and Quality Assurance to include: (1)	Documentation of Service Provided (2)	Quality Assurance Program Remote Monitoring The CSC will provide a toll-free number to monitor the Siemens systems at the NICHD, to include times and days for critical alarms. Holidays and weekend will be monitored 24 hours a day. Siemens is the sole manufacturer and servicer for the Seimens APOGEE and INFOCENTER software. Siemens Industry manufactured and installed all equipment and software for the monitoring and functions for all aspects of the aquatic systems. This includes but not limited to water quality, pump function, dosing modes and temperature. All these factors maintain the health and environment of the species housed in the aquatic facilities. Therefore it is critical that the services, etc being proposed must be able to adequately work/function with the existing equipment's and software, etc. The proposed contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under authority of the 41 U.S.C. 253(c) (1), FAR 6.302. Only one responsible source and no other supplies or services will satisfy agency requirements.The offeror must include a completed copy of the provision of FAR Clause 52.212-3, Offeror Representations and Certifications - Commercial Items with its offer. The provisions of FAR Clause 52.212-1 Instructions to Offerors - Commercial Items; FAR Clause 52.212-2, Evaluation - Commercial Items; FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items; and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items - Deviation for Simplified Acquisitions applies to this acquisition. The offeror must include their Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. The clauses are available in full text at http://www.acquisition.gov/far/. Interested vendors capable of furnishing the government with the specified services in this synopsis should submit a copy of their quotation to the below address or via email to robinsti@mail.nih.gov. Offers must also be accompanied by descriptive literature, delivery timeframe, warranties and/or other information that demonstrates that the offer meets all of the foregoing requirements. Quotations will be due eleven calendar days from the publication date of this synopsis or by December 14, 2015 by 10 am, EST. via email or postal mail. The quotation must reference "Solicitation number" NICHD-16-008. Quotations sent by postal mail or other mailing services must be submitted to the following address: Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Boulevard, Room 5C01, Bethesda, MD 20852. Attention: Tina Robinson, by the date and time mentioned above. Any questions must be sent via email to robinsti@mail.nih.gov and must include solicitation# NICHD-16-008 in the subject line of email. Faxed copies/responses will not be accepted. Note: In order to receive an award, contractor must be registered and have valid certification in the SAM database @www.sam.gov.
NIDCD HS Corporate Work Study Program 2015-2016
This is a combined Synopsis/Solicitation for commercial items prepared in accordance with the format of FAR Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitati ...
Department of Health and Human Services, National Institutes of Health | Published July 23, 2015 - Deadline August 3, 2015
This is a combined Synopsis/Solicitation for commercial items prepared in accordance with the format of FAR Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is NIHDC2015001 and is being issued as a Request for Proposals (RFP). The incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-82 effective June 8, 2015. The North American Industry Classification System (NAICS) code for this procurement is 611110. BACKGROUND INFORMATION: The current workforce is composed of large numbers of baby boomers who are projected to retire at an increasing rate in the next 8 to 15 years. The upcoming retirement wave is anticipated to create a shortage of skilled workers in many occupational areas. To mitigate the effects of this anticipated occurrence organizations in the public and private sectors have begun establishing relationships with high schools to cultivate an entry level supply of labor. Research suggests that one of the careers most vulnerable to these labor market shifts are those of the science, technology, engineering and mathematics (STEM) occupations. NIDCD is interested in partnering with a high school to increase interest in STEM occupations and the NIH/NIDCD, particularly among populations underrepresented in the biomedical research field, and begin to work towards bridging the anticipated shortage of skilled workers in STEM occupations. OBJECTIVE: The National Institutes of Health, National Institute on Deafness and other Communication Disorders (NIH/NIDCD) wishes to participate in a partnership with a high school in Montgomery County, which allows students an opportunity to explore and actively engage in the NIH/NIDCD professional environment. SCOPE: This contract will establish and develop a pipeline of qualified candidates for NIH/NIDCD hiring needs in the next 8 to 15 years. This contract intends to focus solely on initiating a relationship with a high school with a demonstrated track record of successful work study programs with outside organizations. The work study program will introduce participating students to the professional environment of the NIH/NIDCD and provide them with administrative and technical work experience. Also it will provide NIH/NIDCD with entry level services for our intramural program and research management and support. ADMINISTRATIVE: The following provisions and clauses apply to this acquisition: FAR 52.212-1, Instructions to Offerors-Commercial Items (APR 2014); FAR 52.212-2, Evaluation-Commercial Items (OCT 2014); FAR 52.212-3, Offeror Representations and Certifications-Commercial Items (MAR 2015); FAR 52.212-4, Contract Terms and Conditions-Commercial Items (MAY 2015); and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (May 2015). The Contracting Officer's Representative (COR) will be representing the Government for the purpose of this contract. The COR is responsible for: (1) monitoring the Contractor's technical progress, including the surveillance and assessment of performance and recommending to the Contracting Officer changes in requirements; (2) interpreting the statement of work and any other technical performance requirements; (3) performing technical evaluation as required; (4) performing technical inspections and acceptances required by this contract; and (5) assisting in the resolution of technical problems encountered during performance. The Government may unilaterally change its COR designation. The Contracting Officer is the only person with authority to act as agent of the Government under this contract. Only the Contracting Officer has authority to: (1) direct or negotiate any changes in the statement of work; (2) modify or extend the period of performance; (3) change the delivery schedule; (4) authorize reimbursement to the Contractor for any costs incurred during the performance of this contract; or (5) otherwise change any terms and conditions of this contract. Contract Title: NIDCD HS Corporate Work Study Program. Contract Type: A firm fixed price contract is anticipated. Place of Performance: Bethesda, MD. Government Furnished Property: None. Security: HSPD-12 access badge and low-level background check. PROPOSAL DUE DATE/ PACKAGING AND DELIVERY OF PROPOSALS: Inquiries may be emailed no later than 4:00 P.M. EST on July 28, 2015 to kutal@od.nih.gov. NIH will post all inquiries and the Government's responses to Federal Business Opportunities at www.fbo.gov. The RFP closing date is August 3, 2015. Technical and Business proposals shall be submitted as separate files, each in Adobe .pdf format, via email to kutal@od.nih.gov. Proposals must be submitted no later than 4:00 P.M. EST on August 3, 2015.
Utilization of an Analytic Approach Involving an Evolutionary Algorith
Department of Health and Human Services, National Institutes of Health | Published April 17, 2015 - Deadline April 28, 2015
INTRODUCTION This is a pre-solicitation non-competitive (notice of intent) synopsis to award a contract without providing for full or open competition (including brand-name). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institute on Drug Abuse (NIDA), Consolidated Station Support and Simplified Acquisitions (CSS/SA) Branch intends to negotiate and award a purchase order to University of Vermont & State Agricultrural College (UVM) for utilization of an analytic approach involving an evolutionary algorithm developed by UVM without providing for full and open competition (including brand-name). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 541712 with a Size Standard of 500 Employees. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-76 dated July 25, 2014. This acquisition is for a commercial item or service and is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures. This acquisition is NOT expected to exceed the simplified acquisition threshold. STATUTORY AUTHORITY This acquisition is conducted under the authority of the authority of FAR Subpart 13.106-1. DESCRIPTION OF REQUIREMENT Purpose and Objectives The purpose of this contract is to utilize the University of Vermont's (UVM) analytic approach capable of capturing intra- and inter-domain nonlinear interactions Intramural Research Program (IRP) of the National Institute on Drug Abuse (NIDA) Neuroimaging Research Branch (NRB) in order to label interactions among neural, genetic, and phenotypic characteristics that are associated with drug use, nicotine consumption in particular. The UVM Complex Systems group has reported an analytic approach involving an evolutionary algorithm called genetic programming (GP) capable of capturing these intra- and inter-domain nonlinear interactions. Preparation and application of this methodology to NRB data, under the guidance of Dr. Stein, is required. This would be of high value for the NIDA Intramural Research Program as our datasets are typically high-dimensional and multi-domain and likely contain numerous nonlinearities (e.g., inter-regional brain interactions; gene x environment interactions). Period of Performance The period of performance shall be for one (1) year after receipt of order. Project Description The Contractor shall apply this unique analytic method to address the following: (1)	The Contractor shall determine if these biomarkers for smoking are within the resting state functional connectome (i.e., patterns of resting state neural interaction) associated with nicotine use. The Contractor shall determine if any of these interactions confer insight from a clinical or physiological perspective. (2)	The Contractor shall determine if cross-domain interactions exist (e.g., gene-brain) that are associated with nicotine use. (3)	The Contractor shall determine if any associations from (1) or (2) allow for spectrum or categorical classification, rather than just binary classification of smokers. Prepared analysis techniques shall be standardized and the Contractor shall provide training for NRB staff in the use of these algorithms. At the conclusion of the contract period NIDA researchers shall be capable of conducting analyses employing this methodology independently. CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATION The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, only the University of Vermont & State Agricultrural College (UVM) is capable of meeting the needs of this requirement due to the unique methods previously developed by UVM. The Complex Systems group under Dr. Garavan's supervision at UVM provides the unique expertise required for the implementation of the proposed computational methodology. No other group has employed genetic programming (GP) in the analysis of fMRI. Their methodology is capable of capturing these intra- and inter-domain nonlinear interactions needed for the analysis required by the NRB. The UVM group has applied GP to define hierarchical network structure in the resting state, adolescent brain. Results of that study, which were presented at the 2014 OHBM conference in Hamburg, Germany (Allgaier et al., 2014) suggested likely differences (some nonlinear) in resting state functional connectome between teenagers who consume alcohol and those who don't within the IMAGEN dataset. The data captured using this methodology will be of high value for the NIDA Intramural Research Program as the datasets are typically high-dimensional and multi-domain and likely contain numerous nonlinearities (e.g., inter-regional brain interactions; gene x environment interactions). The intended source is: University of Vermont & State Agricultrural College (UVM) 85 S. Prospect Street Burlington, VT 05405 CLOSING STATEMENT THIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by the closing date and time of this announcement and must reference the solicitation number. Responses may be submitted electronically to Megan Ault, Contract Specialist, at megan.ault@nih.gov. US Mail and Fax responses will not be accepted.
Vector Analysis of Replication-Competent Retrovirus (RCR)
The U.S Department of Health and Human Services, National Institutes of Health, National Cancer Institute (NCI), Center for Cancer Research (CCR), Pediatric Oncology Branch plans to procure, on a sole source basis, services for Vector Analy ...
Department of Health and Human Services, National Institutes of Health | Published August 20, 2015 - Deadline September 1, 2015
The U.S Department of Health and Human Services, National Institutes of Health, National Cancer Institute (NCI), Center for Cancer Research (CCR), Pediatric Oncology Branch plans to procure, on a sole source basis, services for Vector Analysis of Replication-Competent Retrovirus (RCR) in ongoing clinical trials, to Indiana University Vector Production Facility (IU VPF), of Indiana University School of Medicine, 980 West Walnut Street, Indianapolis, IN 46202. This acquisition will be processed in accordance with simplified acquisitions procedures as stated in FAR Part 13.106-1(b)(1) and is exempt for the requirements of FAR Part 6. The North American Industry Classification System code is 541380, and the business size standard is $15.0 Million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. The anticipated period of performance shall be September 15, 2015 through January 31, 2016. It has been determined there are no opportunities to acquire green products or services for this procurement. BACKGROUND The NCI/CCR/Pediatric Oncology Branch is committed to bringing new cutting edge therapies to children with leukemia. The Pediatric Oncology Branch has been instrumental in treating children with T lymphocytes (white blood cells from the patient) that have been modified with retroviral gene vectors. The Pediatric Oncology Branch currently has an open clinical trial for T cells modified with a chimeric antigen receptor (CAR) specific for the leukemia tumor antigen CD19. In the trial, the Pediatric Oncology Branch is conducting a trial of immunotherapy for the patients with leukemia and solid tumors, in which lentiviral vectors and gamma retro viruses are used as important tools to achieve long-term expression and stable integration of a gene of interest in a target cell, such as CD19 CAR in T cells, etc. A principle concern regarding the use of either lentiviral or gamma retroviral vectors is the potential to generate a retrovirus (RCR). The known pathogenicity of leukemia retroviruses (RCRs) associated with these vectors requires strict monitoring of gene therapy products. At present, the Food and Drug Administration (FDA) has set forth to perform RCR detection primarily by a combination of biological (extended S+/L- assay) and molecular methods (PCR) for retroviral vectors, and p24gag ELISA/gag PCR for lentiviral vectors. The Contractor shall provide a laboratory environment which conforms to good manufactory practice requirements mandated by the FDA, in order to perform Vector Analysis of Replication Competent Retrovirus (RCR) for 13 samples. Lab equipment shall be suitably sized and located to facilitate maintenance, cleaning and proper operation. All testing facilities shall have written standard operating procedures in place to define nonclinical study methods in laboratory settings. The quality assurance is in place to monitor each study by ensuring that the equipment, facilities, staff, test methods and documentation conform to written regulations. The tests shall be conducted on CCR's gene products using clinical Good Manufacture Protocol (cGMP) standards and the results shall be provided to the NCI Contracting Officer's Representative (COR) to be included in the submission packet to the FDA for the Investigative New Drug (IND) for this product. TASKS The Contractor shall: 1. Perform Vector Analysis of Replication Competent Retrovirus (RCR) for 13 samples. 2. Perform a quality assurance review of manufacturing records and test results for compliance with FDA standards: • Facilities must be designed to keep separate all testing areas, so as to ensure that no lab results can be affected by accidental mishaps. • All equipment, such as computers and manufacturing machines, must be routinely inspected, calibrated and checked according to written regulations designed to ensure proper performance. • Written records of all inspections, calibrations and checks must be kept for management review (in the contractor for further references). IU VPF is the only facility that can analyze a cell line that can be used by the CCR / Pediatric Oncology Branch for clinical studies, using a technology that insures cGMP-grade manufacture and FDA compliance of the producer line, which is required for future clinical studies. Only IU VPF has a track record of consistently producing such lines in a clinic-ready manner. This is a highly custom assay, created in part by intellectual property held by HHS/NIH, created by the requesting laboratory. In researching this product, the Pediatric Oncology Branch found only one other lab capable of custom retroviral vector producer line assay, but the assay is not equivalent as it does not begin with a pre-FDA approved cell line, and no economy of scale can be granted at that facility. It is only at the IU VPF where the CCR / Pediatric Oncology Branch's request can be met. This is not a solicitation for competitive quotations. However, if any interested party especially small business, believes they can meet the above requirement, they may submit a capability statement, proposal, or quotation which will be considered by the agency. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the needs of the requirement described herein. Reponses must be submitted via email only to Contract Specialist, Megan Kisamore, at Megan.Kisamore@nih.gov, no later than 11:00 am EST, Tuesday, September 1, 2015. All questions must be emailed to Megan.Kisamore@nih.gov. Capability statements will not be accepted after the due date. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the System for Award Management (SAM) at www.sam.gov. No collect calls will be accepted. Please reference solicitation number N02RC52690-76 on all correspondence.
Architectural and Engineering Liaison
Department of Health and Human Services, National Institutes of Health | Published June 11, 2015 - Deadline July 10, 2015
COMBINED SYNOPSIS / SOLICITATION This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is HHS-NIH-NIDA-(SSSA)-15-377 and the solicitation is issued as a request for proposal (RFP). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Test Program for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is expected to exceed the simplified acquisition threshold. The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2005-82 effective May 7, 2015. This acquisition is set aside 100% for small businesses. The associated NAICS code 541611 and the small business size standard $15.0. STATEMENT OF OBJECTIVES The objective is to acquire a liaison to provide architectural and engineering administrative and managerial support services to facilitate renovation projects for NINDS. Title: Architectural and Engineering Liaison The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life and reduce illness and disability. The National Institutes of Health is comprised of 27 Institutes and Centers. The National Institute of Neurological Disorders and Stroke (NINDS), is one of those member institutes. The NINDS' mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. NINDS DIR seeks an independent contractor to provide day-to-day, on-site liaison services of an architectural and engineering nature to satisfy the overall operational objectives of the National Institute of Neurological Disorders and Stroke. It is anticipated that the number of spaces requiring Architectural and Engineering support and therefore requiring attention from the liaison will increase during the duration of this agreement. The individual shall work as a liaison between NINDS leadership, operations staff, Principal Investigators (PIs), construction personnel, the scientific community and other relevant stakeholders to serve as an intermediary between the aforementioned parties as they analyze project requirements, discuss plans, formulate alternate solutions and implement the finalized plan to provide services and deliverables through to successful project completion. Scope of Work The contractor shall: 1.	Serve as a liaison between leadership, construction and scientific communities for multiple projects simultaneously. 2.	Serve as a point of contact between the Scientific Director, EO offices, NINDS investigators, and NIH facility management. 3.	Prepare and present planning and status reports for project officer approval. 4.	Collaborate with leadership, construction, scientists, and financial personnel to ensure funding and timeline goals are met. 5.	Possess the knowledge to work in biomedical investigative and active Continuity of Operations (COOP) environments. 6.	Possess experience assisting in successfully relocating individuals and groups of 1 - 500 people and their technical environments, labs, utilities, furniture, etc. 7.	Possess an understanding of planning swing spaces. 8.	Shall have experience presenting plans and obtaining buy-in from leadership, construction, finance and scientific communities. 9.	Possess an Occupational Safety Hazard Administration (OSHA) Certificate 10.	Shall have strong organizational, interpersonal and time / management skills. Key Personnel Requirements Certifications required of the candidate: 1.	Certified Professional Engineer (PE) 2.	Certified Construction Manager (CCM) 3.	LEED Accredited Professional (AP+BD+C) Key personnel proposed for the current position must possess: 1.	Either a Bachelor's degree in an Engineering specialty related to construction; Or a Bachelor's degree and 4 years' experience with HVAC, electrical, utilities, etc; 2.	AND 8+ years' Federal Government construction/renovation experience; 3.	AND 5+ years' experience in laboratory projects; Qualifications should be easily identifiable in a resume or a clearly delineated section of the proposal. Period of Performance Base Year: September 1, 2015 - August 31, 2016 Option Year 1: September 1, 2016 - August 31, 2017 Option Year 2: September 1, 2017 - August 31, 2018 Option Year 3: September 1, 2018 - August 31, 2019 Option Year 4: September 1, 2019 - August 31, 2020 Please refer to the attached Statement of Work for further detail, specifications, and evaluation criteria. FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. Offerors must include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, with its offer. FAR clause 52.212.-2, Evaluation - Commercial Items, is applicable to this requirement. Offers will be evaluated on: Item #	Technical Requirements Score Points 1	Demonstrate ability to consult with leadership, construction and scientific communities regarding multi-function collaboration to accomplish Investigative Spaces from concept to fruition. Demonstrate ability to understand and be able to accurately communicate technical, construction, budget/ finance, new tenure track hire and NINDS leadership data and points of view, present and advance tradeoffs in manner that facilitates concurrence from all parties. 10 2	Demonstrate ability to simultaneously serve as a liaison for 15-20 projects at the same time meeting the objectives of each.	10 3	Demonstrate ability to act as point of contact among Scientific Director (SD) and EO offices, NINDS investigators, and NIH facility management.	10 4	Demonstrate ability to collect data, generate detailed status and planning reports for project officer approval, and present reports to top to mid-management leadership, to construction teams, and to investigative and experimenting scientists.	5 5	Demonstrate ability to collaborate and coordinate among leadership, construction, scientific and budget/finance communities to ensure efficient use of funding and to adhere to schedule for new and renovation projects.	5 6	Demonstrate sufficient knowledge of shaping a biomedical investigative environment containing HVAC, nitrogen(N2), carbogen (CO2O2), carbon dioxide (CO2) [lab vacuum, lab gases, lab air], bio-hazard storage, freezer farms, fume hoods, bio-safety cabinets, air tables, centrifuges and vivariums so that concerns from different parties regarding biomedical investigative environments can be addressed , detailed, and properly relayed to the appropriate parties.	10 7	Demonstrate experience operating in an active Continuity of Operations (COOP) environment containing live research specimen since liaison services in such an environment may be necessary and knowledge of the environment will be necessary to serve as an effective intermediary in such situations. Please see http://www.ors.od.nih.gov/ser/depc/Pages/coop.aspx for more detailed information.	10 8	Provide evidence of the ability to ensure that renovation projects proceed on schedule and on budget, to inform SD and EO or equivalent offices of possible deviations from schedule and budget, and to collaborate with staff to find solutions that may arise thereby keeping projects on schedule and within budget. 8 9	Demonstrates familiarity with and ability to work with NINDS' Continuity of Operations (COOP)/Emergency personnel and team responders in the event of building emergencies by giving specific experience of employing protocols working with emergency personnel and team responders.	8 10	Evidence of strong communication skills: oral, written, and in presenting material to a group. 10 11a.	Display an ability to collaborate with the appropriate parties in the oversight and implementation of a chlorination system for animal vivarium which houses an average of 12,000 mouse/rat cages. Currently, the water system is contaminated, research is affected and behavioral studies are also affected; the ability to serve as an intermediary in order to help resolve these and/or similar challenges should be detailed. 5 11b.	Display an ability to collaborate with the appropriate parties in the oversight of the study and renovation of an animal quarantine area including the assessment of HVAC and installation of ducted biosafety cabinets.	3 11c.	Display an ability to serve as a liaison with the parties involved with the renovation of specifically designed animal holding areas that must be continued for virus-infected rodents. 6 Technical Score:	100 KEY PERSONNEL REQUIREMENTS Key personnel proposed for the current position must possess: 1	Either a Bachelor's degree in an Engineering specialty related to construction; Or a Bachelor's degree and 4 years' experience with HVAC, electrical, utilities, etc;	Pass/Fail 2	AND 8+ years' Federal Government construction/renovation experience;	Pass/Fail 3	AND 5+ years' experience in laboratory projects;	Pass/Fail Certifications required of the candidate: 1	Certified Professional Engineer (PE)	Pass/Fail 2	Certified Construction Manager (CCM)	Pass/Fail 3	LEED Accredited Professional (AP+BD+C)	Pass/Fail The evaluation will be based on the evaluation of the proposal in relation to the scope of work and the evaluation criteria. Paramount consideration shall be given to the evaluation of technical factors. Although technical factors are of paramount consideration in the award, cost or price is also important to the overall task order award decision. All evaluation factors other than cost or price, when combined, are significantly more important than cost or price. However, cost or price may become a critical factor in source selection in the event two or more offers are determined to be essentially equal following the evaluation of all factors other than cost or price. Cost-price will be evaluated for reasonableness in relation to the requirements of the contract. In addition, a final best-buy analysis will be performed taking into consideration the results of the technical evaluation, cost-price analysis, and the offeror's ability to complete the work within the Government's required schedule. An award will be made to the offeror whose proposal conforms to the requirements of the scope of work and is most advantageous to the Government with technical merit, cost-price, and other factors considered. The Government reserves the right to reject any or all offers or any part thereof and to waive any minor informality or irregularity in offers received. FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses must be received by July 10, 2015, 8:00 am EST and must reference number HHS-NIH-NIDA-(SSSA)-15-177. Responses must be submitted electronically to andriani.buck@nih.gov and by U.S. mail to the National Institute of Drug Abuse (NIDA), Station Support / Simplified Acquisition Branch (SS/SA), 31 Center Drive, Building 31, Room 1B59, Bethesda, Maryland 20892-2080, Attention: Andriani Buck. Fax responses will not be accepted. The hard copy documents must comply with FAR 52.204-4 -- Printed or Copied Double-Sided on Postconsumer Fiber Content Paper. Printed or Copied Double-Sided on Postconsumer Fiber Content Paper (May 2011) (a) Definitions. As used in this clause- Postconsumer fiber means- (1) Paper, paperboard, and fibrous materials from retail stores, office buildings, homes, and so forth, after they have passed through their end-usage as a consumer item, including: used corrugated boxes; old newspapers; old magazines; mixed waste paper; tabulating cards; and used cordage; or (2) All paper, paperboard, and fibrous materials that enter and are collected from municipal solid waste; but not (3) Fiber derived from printers' over-runs, converters' scrap, and over-issue publications. (b) The Contractor is required to submit paper documents, such as offers, letters, or reports that are printed or copied double-sided on paper containing at least 30 percent postconsumer fiber, whenever practicable, when not using electronic commerce methods to submit information or data to the Government. (End of Clause) The technical proposal excluding all cover pages, table of contents, resumes and cost proposals must be limited to twenty five (25) pages in length. The font for both the technical and cost proposal must be either 11 or 12 point Arial or Times New Roman. Contact Andriani Buck at andriani.buck@nih.gov for information regarding the solicitation. Questions should be limited to five (5) per vendor and be submitted by June 22nd, 2015. Responses to questions for clarification will be posted as a modification to this solicitation.
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