Source: https://russianpatents.com/patent/238/2388480.html
Timestamp: 2020-08-09 02:35:01
Document Index: 385110890

Matched Legal Cases: ['art 1', 'art 1', 'art 1', 'art 1', 'art 2', 'art 2', 'art 1', 'art 1', 'art 1', 'art 1', 'art 2', 'art 2', 'art 1', 'art 1', 'art 1']

Agent for preventing and treating inflammatory processes among animals
A61K36/66 - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J0003000000; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L)
SUBSTANCE: invention concerns veterinary medicine, namely to agents prepared from medical plants. The invention consists in the following. Mixture of the following medical plants crushed to fine and ultrafine particles and treated with bactericidal lamps rays are placed in a sterile tank of dark glass: dry stalks, leaves and flowers of peppermint, dry flowers of wild chamomile, dry leaves of waybread and dry flower heads of costmary (Tanacetum vulgare), dry stalks, leaves and flowers of yellow melilot, dry grass of St. John's wort, dry flowers of pot marigold, dy grass of milfoil, dy grass of thyme, dry stalks, leaves, flowers and fruits of celandine, dry leaves of eucalyptus, dry leaves and flower heads of coltsfoot, dry leaves of garden sage, dry leaves of stinging nettle, dry grass of common persicaria, dry flowers of densely flowered mullein, bark of ordinary oak, roots of common licoric, ground fruits of anise and rose hips, walnut kernel, buckthorn pulp without kernels, their fruits and berries. These components are treated with bactericidal lamps rays and crushed to fine and ultrafine particles, then placed to a tank of dark glass, mixed with sterile cooking salt solution with 0.9% sodium content, and with formalin. The mixture is left and room temperature for 3-4 days, regularly stirred, and then placed to water bath for 10-12 hours and exposed to temperature up to 40�, with contiuous stirring. After that the liquid part is separated from the vegetable sediment. The tincture is stored in tanks of dark glass or in a darkened room at a temperature of 2-4�C, and is applied externally and internally, and the vegetable sediment is used as fodder and remedy for animals and birds, especially for chickens in case of cannibalism.
The present invention relates to veterinary medicine, particularly to drugs from medicinal plants for the prevention of the development and treatment of inflammatory processes on the surface of the body and inside the body.
It is known that for many centuries, mankind uses many plants for toning functions, treatment of diseases of the external and internal organs, taking the infusion, decoctions, residue and other pharmaceutical forms. We believe that the extraction of medicinal substances from medicinal plants water with a temperature above 40�C in solvent extracts and medicinal substances that can interact with cells and tissues of the hearth damage to the body or organ, even though due to the difference of temperature of extraction and the steps they can even inhibit the interaction of therapeutic substances, in addition, when exposed to the medicinal plants of high temperatures, temperatures above 60�C, many therapeutic agents are destroyed and obtained the drug has no medical properties, defined by nature.
The purpose of the invention is to increase the efficiency of vodorazdelny infusions, rational use of medicinal plants for maximum extraction of active medicinal substances.
This objective is achieved in that in the dry sterrenwacht dark glass was placed a mixture of chopped up fine and ultra-fine particles treated with germicidal rays following medicinal plants when their ratio in the mixture of 25.0 g (of 0.82 wt.%): dry stalks, leaves, flowers, peppermint, dried chamomile flowers, dried leaves of plantain, dried flower baskets tansy, dry stems, leaves, flowers, fruits clover medicinal, dry grass Hypericum perforatum, dried flowers calendula medicinal, dry grass of a yarrow, dry grass thyme, dried stems, leaves, flowers, fruits celandine, dry leaves of the eucalyptus, dried leaves and flower baskets mother-and-stepmother, dried leaves of Salvia officinalis, dried leaves of nettle, dry grass Polygonum persicaria, dried flowers Corolla mullein gostinechnogo, oak bark, the roots of licorice, crushed fruits of anise and rose brown, kernels of the fruit of the walnut, the pulp without seed oil of sea-buckthorn berries, mix vegetable raw materials by weight 550,0 g (18.0 wt.%) with 2500,0 g (81,4 wt.%) 0,9%in sodium chloride sterile solution of sodium chloride, added to 20.0 g (0.6%) formalin, leave the mixture at room temperature and stirring until 3-4 days, then the receptacle containing the mixture is placed in a water bath for 10-12 hours and maintained at a temperature up to 40�C under stirring, separating the liquid part from vegetable raw materials, store it in dark glass containers or in a dark place at a temperature of 2-4�C, apply the tool externally and inside, the vegetable on which the headed the remainder is used as fodder and therapeutic tool.
Rationale cooking techniques offer tools
During grinding of medicinal plants to fine and ultra-fine particles and heating them up to 58-59�C are not destroyed and does not disintegrate medicinal substances greatly increases the total surface contact them with 0.9%saline, extracting at room temperature provitamins, vitamins, episodenguide and other medicinal substances that may interact with cells and tissues of the hearth damage or inflammation of the animal, when the grinding and processing of medicinal plants, in which the temperature is above 60�C, many medicinal substances decompose, disintegrate or infusion of extracted substances, which cannot interact with cells of the hearth damage even on the difference in temperature regimes, they will only hinder access to sick cells evoked potential medicinal substances extracted into the flask at a temperature of 40�C.
Technology of preparation of the medicinal product
1. Need sample selected for preparing medicinal plants are placed in a thin layer on the table, treat them the rays of the lamps, with some provitamins converted into vitamins, activation of some medicinal substances.
2. Dry part l of the drug plants the roots of licorice, anise fruit and briar brown crushed to fine and ultra-fine particles, but their temperature should not be higher 58-59�C, the fruits of walnut initially crushed in a porcelain mortar, and then in the mill in a mixture with the dry parts of plants, sea-buckthorn berries into a pulp without seed and put it in a container of dark glass, mix vegetable raw materials with 0.9%sterile sodium chloride solution.
3. The mixture in the vessel leave at room temperature and stirring until 3-4 days, then placed in a water bath for 10-12 hours and maintained at a temperature up to 40�C under stirring.
Note: when the testimony plant material incubated in 0.9%saline repeatedly.
4. Chilled water infusion is separated from the plant material, retain it in containers of dark glass or a dark place at a temperature of 2-4�C.
5. Waste vegetable raw materials included in the diet of pigs and chickens as a food and a therapeutic agent, chickens especially when rackleff (cannibalism).
Pharmacodynamics ingredients of the medicinal product (drug):
- in the stems, leaves, flowers, peppermint leaf contains substances with local anesthetic, antispasmodic, wound healing, anti-inflammatory action (1, 2-nd, s.138; 2, C; 3, part 1-I, who .346; 6, s);
- substances flowers of chamomile have anti-inflammatory, hemostatic, antiseptic, astringent, analgesic, sedative, anticonvulsant, antispasmodic, disinfectant effect, reduce the tension of cells and tissues, accelerate the growth and development of cells of granulation tissue (1, 2-nd, s; 2, C; 3, part 1-I, s; 4, C; 6, C-250);
- substances plantain leaves have anti-inflammatory, bacteriostatic, wound healing, anti-sclerotic, antispasmodic effect (2, p.�192; 3, part 1-I, s; 6, s);
- in the flower baskets tansy contains substances that have anti-inflammatory, antibacterial, antihelminthic effect on Ascaris and pinworms (2, p.189-191; 6, s-237);
- in thin stems, leaves, flowers, fruits clover drugs are substances that have anti-inflammatory, antispasmodic, narcotic, distracting, lenitive action (1, 1-th, s; 2, C; 6, p.95);
herb Hypericum perforatum contains substances that have anti-inflammatory, astringent, hemostatic, antimicrobial effect, stimulating effect on the growth and development of cells in wounds and burns 2nd & 3rd degree (2, p.116; 3, part 1-I, s; 6, s);
- substances flower baskets calendula officinalis (calendula) have about ilovepeterpan, bactericidal, wound healing, antispasmodic effect (2, pagination 126; 3, part 2-I, s; 6, s);
- the substance is dry herb yarrow have anti-inflammatory, hemostatic, wound healing, analgesic action (1, 1-th, s; 2, C; 3, part 2-I, p.86; 4, p.223; 6, s.293);
- thyme herb contains substances that have anti-inflammatory, disinfectant, analgesic, sedative effect (2, C; 3, part 1-I, s);
the stems, leaves, flowers, fruits celandine contain substances that have a fungistatic, bacteriostatic, analgesic, spasmolytic effect (1, 2-nd, s; 2, pp.261-262; 6, s-329);
- substance of the leaves of eucalyptus ball, ash, stiff rod anti-inflammatory, analgesic, antispasmodic, antiseptic, expectorant action, contribute to the growth and maturation of cells of granulation tissue (2, pp.272; 3, part 1-I, s; 4, C; 6, C);
the leaves and flower heads, the mother-and-stepmother ordinary contain substances that have anti-inflammatory, softening, antispasmodic, expectorant, coating, antimicrobial effect (2, C; 3, part 1-I, s; 6,0 .180);
- in the stems, leaves, flowers of Salvia officinalis contains substances that have anti-inflammatory, astringent, disinfectant, antimicrobial activity (1, 2-nd, s.255; 2 s; 3, part 1-I, s; 4, C; 6, C-331);
- in the leaves of nettle contain vitamins and substances with hemostatic effect, substance, contributing to an increase in blood hemoglobin, stimulating the growth and development of cells of granulation tissue (2, p.142; 3, part 2-I, p.86; 6, s-135);
herb Polygonum persicaria contains substances with styptic and antibacterial effect (2, p.95; 3, part 2-I, p.86; 6, P80);
flowers - Corolla mullein gostinechnogo (scepter-shaped) contain substances that have anti-inflammatory, softening, soothing, astringent, enveloping, protiwastmaticescoe action (1, 1-th, s; 2, p.140; 4, C; 6, p.140);
- the substance of the bark of oak have astringent, anti-inflammatory, hemostatic effect (1, 1-th, s; 2, pp. 102; 3, part 1-I, s; 4, C; 6, p.98);
in the roots of licorice contains a substance that has anti-inflammatory, analgesic, enveloping, expectorant, mild laxative effect (2, s-226; 4, s-218; 6, p.260-264);
- substances of the fruits of anise ordinary anti-inflammatory, antipyretic, expectorant, mild disinfectant action (1, 1-th, p.34; 2, C) 3, part 1-I, s; 4, C; 6, p.29);
- the fruits of full maturity rose brown rose brown, thorny roses, roses Daur, rose Fedchenko and other types of roses CE is ASTA colorful and wild rose dog) contain vitamins and provitamins, anti-inflammatory, antipyretic, diuretic substances that contain substances that reduce the permeability and fragility of capillaries, substances inhibiting the development of atherosclerosis in stimulating the growth and development of cells of granulation tissue (2, s.226; 3, h 2-I, p.30 and 46; 4, s, 316; 6, s);
- the kernel of the fruit of the walnut tree contain substances and oils that have anti-inflammatory, antibacterial, anti-sclerotic, styptic, astringent, epithelization, wound-healing effect (5, p.34-42);
- substances pulp of fruits of sea-buckthorn have anti-inflammatory, analgesic, necrotic, astringent, stimulates reproduction, growth and development of granulation tissue, delay the development of degenerative changes in the inflamed area with radiation skin lesions (3, C.2-I, p.47; 6, p. 203);
to 0.9%in sodium chloride salt solution contains other mineral substances, not only the cells of the lesion, but also throughout the body (6, s);
the formalin is an aqueous solution of formaldehyde - transparent liquid with a peculiar pungent smell, has antimicrobial, disinfectant action, used as a preservative (1, 2-nd, C; 4, s-478).
In view of the fact that the proposed tool (vodorazdelny infusion, the drug contains many therapeutic washes the VA medicinal plants, proven centuries-old practice of traditional medicine, undamaged effect of temperatures above 60�C, it has the properties of plants gifted by nature healing properties.
In experimental tests of the performance of the funds (preparation) obtained are quite encouraging results corresponding to literary sources.
We believe that the proposed remedy, prepared without exposure to the medicinal plants of high temperatures, will be widely used in veterinary medicine.
1. Veterinary dictionary. M: Selhozizdat, volume 1 and 2, 1950 and 1951, respectively.
2. Kovalev N.G. Treatment plants. M.: Medicine, 1971
3. Mashkovsky PPM Medicines. M.: Medicine, part 1-I 2-I, 1987
4. Brain I.E. Pharmacology. M: Selhozizdat, 1954
5. Nesterov A.V. Black and walnuts against cancer. LLC "ID REEPOL classic" 107140, Moscow, Krasnoprudnaya street 22 a, p. 1. Ed. violence. No. 04620 from 24.04.2001,
6. Schr�ter A.I., Muraviev D.A., Pakorn D.A., Efimova F. W. Medicinal flora of the Caucasus. M.: Medicine, 1979
1. Means for preventing and treating inflammatory processes in animals containing medicinal plants, characterized in that in a dry sterile container dark glass was placed a mixture of chopped up m is lcih and the smallest particles treated with germicidal rays following medicinal plants when their ratio in the mixture of 25.0 g (of 0.82 wt.%): dry stalks, leaves, flowers, peppermint, dried chamomile flowers, dried leaves of plantain, dried flower baskets tansy, dry stems, leaves, flowers, fruits clover medicinal, dry grass Hypericum perforatum, dried flowers calendula medicinal, dry grass of a yarrow, dry grass thyme, dried stems, leaves, flowers, fruits celandine, dry leaves of the eucalyptus, dried leaves and flower baskets mother-and-stepmother, dried leaves of Salvia officinalis, dried leaves of nettle, dry grass Polygonum persicaria, dried flowers Corolla mullein gostinechnogo, oak bark common, the roots of licorice, crushed fruits of anise and rose brown, kernels of the fruit of the walnut, the pulp without seed oil of sea-buckthorn berries, mix vegetable raw materials by weight 550,0 g (18.0 wt.%) with 2500,0 g (81,4 wt.%) 0,9%in sodium chloride sterile solution of sodium chloride, added to 20.0 g (0.6%) formalin.
2. Means for preventing and treating inflammatory processes in animals according to claim 1, characterized in that the mixture is left at room temperature and stirring until 3-4 days, then the receptacle containing the mixture is placed in a water bath for 10-12 h and incubated at 40�C under stirring.
3. Means for preventing and treating Vespa is sustained fashion processes in animals according to claim 1, characterized in that the separated liquid part from vegetable raw materials, store it in dark glass containers or in a dark place at a temperature of 2-4�C, apply the tool externally and internally, vegetable residue is used as fodder and therapeutic tool.
Application of dihydromidasopirazine for pain prevention or management // 2388474
SUBSTANCE: invention proposes application of (1R)-1-[({(2R)-2-amino-3-[(8S)-8-(cyclohexyl-methyl)-2-phenyl-5.6-dihydromidazo[1.2-a]pyrazin-7(8H)-yl]-3-oxopropyl}ditio)methyl]-2-[(8S)-8-(cyclohexylmethyl)-2-phenyl-5.6-dihydromidazo[1,2-a]pyrazin-7(8H)-yl]-2-oxoethylamine and pharmaceutically acceptable salts thereof for obtaining a remedy for pain prevention or management. In particular, pains provoked by neuropathy and/or inflammation, other chronic diseases: cancer, radiculopathies, painful obesity, migraine, chronic diseases, fibromailgia, algoneurodistrophy, or complex local pain syndrome, brain vascular diseases, arthrosis, arthritis, diabetic neuropathies or neuropathies due to HIV, sciatica, painful muscle contractions, intoxication, scalds, posthepeic neuralgias, thalamus disease or disseminated sclerosis, or pre- and/or postsurgical pains.
EFFECT: reduction of pain sensitivity threshold at hyperalgesia and at taxol induced neuropathy.
SUBSTANCE: agent for prevention of development and treatment of inflammatory processes in animals is represented by a medication, for preparation of which the mixture of the following components ground to fine and ultrafine particles, which are treated with beams of ultraviolet lamps is placed into dry sterile reservoir made of dark glass, such as medicinal plants at their ratio in powder of 25.0 g (by 1.25 wt %): dry leaves, stems, flowers of peppermint, dry flowers of wild chamomile, dry leaves of costmary anthodes, dry leaves, stems, flowers, fruit of plaster clover, dry herb of touch-and-heal, dry flowers of pot marigold (calendula), dry herb of yarrow, dry herb of thyme, dry leaves, stems, flowers, fruit of killwort, dry leaves of eucalyptus, dry leaves and anthodes of foalfoot, dry leaves of garden sage, dry leaves of stinging nettle, dry herb of lady's thumb, dry flowers of densely flowered mullein corolla (dense mullein), ground fruit of anis and fruit of cinnamon rose, ground kernels of walnut fruit, seedless pulp of sea-buckthorn (if not available, sea-buckthorn oil), vegetable raw materials with weight of 500.0 g (25 wt %) is mixed with 1500.0 g (75 wt %) of vegetable oil (corn, sunflower-seed, olive). After maintenance at room temperature and permanent mixing during 10 days, dark glass reservoir with mixture is placed into water bath for 5 days at the temperature of up to 40�C. Oil infusion is separated from vegetable raw materials, preserved at the temperature of 2-4�C in dark glass reservoirs or in dark room.
Night face gel cream // 2388459
SUBSTANCE: invention relates to cosmetics, namely to products for night face care, aimed primarily at nourishing and normalisation. The night face gel cream contains cream base DTM+ with ephtiderm, jojoba, avocado, wheat-germ and hemp oils, aloe vera, collagen, hawthorn, horse chestnut, motherwort, chamomile, extrapone V, propolis, perfume and vitamin B2 in a certain proportion, in % wt.
EFFECT: cream has a pronounced antibacterial, reparative, whitening and moisturising effect.
Antibacterial and antiinflammatory ointment for oral cavity care // 2388458
SUBSTANCE: invention concerns stomatology. The composition contains a combination of active components, with one or more active compounds from magnolia extract and dried hop cones. Preferably, active components of magnolia extract contain honokiol and magnolol, while active components of dried hop cones contain hexahydrogenated beta-acids. The composition for oral cavity can be presented in the form of oral cavity elixir or dentifrice, including toothpaste, gels, powders, sweets, lozenges, animal products etc. A method for preparation and application of this composition for oral cavity is proposed.
EFFECT: creation of an effective antibacterial and anti-inflammatory composition for oral cavity against dental deposit, against gingivitis and against inflammation.
21 cl, 1 ex, 1 tbl
Breath refresher for disinfecting oral cavity and containing magnolia bark extract and surface active substance // 2388457
SUBSTANCE: invention relates to cosmetic industry, especially to compositions for oral cavity care. Breath-refreshing composition for oral cavity care containing an agent for delivery into the oral cavity and an antibacterial agent composed of magnolia bark extract and an anion surface-active substance (versions).
EFFECT: composition (versions) has enhanced inhibinting effect on the oral cavity biofilm growth as well as breath refreshing effect, due to components synergy.
24 cl, 15 tbl
Compositions for oral cavity containing rosmarinus extracts and associated methods // 2388456
SUBSTANCE: invention relates to cosmetic industry, specifically to compositions for oral cavity care. Toothpaste composition containing moisturiser, abrasive material, rosemary extract which contains ursolic acid and carnosine acid, and antibacterial substance containing halogenated diphenyl ether compound. Dentifrice composition. Mouthwash composition. Chewing composition. Edible oral strip composition.
EFFECT: composition for oral cavity care ensures enhanced anti-inflammatory and antibacterial effect.
26 cl, 5 tbl, 11 ex
Oral cavity treatment compositions containing release agent, antibacterial agent and incompatible compound // 2388455
SUBSTANCE: invention relates to stomatology and is a oral cavity treatment composition containing: a release agent (cysteine protease), a cationic antibacterial agent and a compound which is compatible with neither the release agent nor the antibacterial agent. The compound is separated from the incompatible release agent and the antibacterial agent by encapsulation in the dose vehicle, with subsequent destruction of the encapsulation in the oral cavity.
EFFECT: invention provides a product with enhanced effect of hindering bacteria clumping in the dental deposit.
20 cl, 5 ex, 4 tbl