Source: https://patents.google.com/patent/DE102010016854A1/en
Timestamp: 2019-11-12 14:26:29
Document Index: 80076699

Matched Legal Cases: ['art 15', 'art 15', 'art 15', 'art 15', 'art 15', 'art 15', 'art 15']

DE102010016854A1 - Retaining device for vertebral bodies of the spine - Google Patents
Retaining device for vertebral bodies of the spine
DE102010016854A1
DE102010016854A1 DE201010016854 DE102010016854A DE102010016854A1 DE 102010016854 A1 DE102010016854 A1 DE 102010016854A1 DE 201010016854 DE201010016854 DE 201010016854 DE 102010016854 A DE102010016854 A DE 102010016854A DE 102010016854 A1 DE102010016854 A1 DE 102010016854A1
DE201010016854
Dr. Kast Erich
2010-05-10 Application filed by Ulrich GmbH and Co KG filed Critical Ulrich GmbH and Co KG
2010-05-10 Priority to DE201010016854 priority Critical patent/DE102010016854A1/en
2011-11-10 Publication of DE102010016854A1 publication Critical patent/DE102010016854A1/en
A spinal column vertebral support device (20a, 20b, 20c, 20d) comprises an implant (1) to be inserted into a vertebral body and a pedicle rod (2). The implant (1) has a cavity (3) for the mobility of the pedicle rod (2) and the pedicle rod (2) is in the cavity (3) for permanent mobility of the pedicle rod (2) with respect to the implant (1). arranged.
The invention relates to a holding device for the vertebral body of the spine and in particular relates to a holding device for vertebral bodies of the spine with an implant to be introduced into the vertebral body and a pedicle rod.
In a conventional vertebral body support device, the pedicle rod is rigidly disposed in the implant, and its orientation can be determined via fixation devices on a connection rod between two pedicle rods. This embodiment has the disadvantage that the stabilization of the vertebral bodies is rigid, whereby the range of motion is limited.
The invention is therefore based on the object, a holding device for the vertebral body of the spine of the type mentioned in such a way that the disadvantages of conventional holding devices can be overcome in terms of the scope of movement.
According to a first aspect of the present invention, this object is achieved in the aforementioned holding device in that the implant for the mobility of the pedicle rod has a cavity and that the pedicle rod is disposed in the cavity for permanent mobility of the pedicle rod with respect to the implant. This embodiment has the advantage that a dynamic segmental stabilization with a center of rotation in the region of the physiological center of rotation can be achieved ventrally from the pedicle plane. This causes a largely physiological movement pattern. An additional advantage is that effective protection of terminal degeneration and preservation of greater range of motion can be achieved.
It has proven to be advantageous if the implant has a sleeve-shaped configuration, whereby the introduction of the implant is facilitated in the vertebral body.
The pedicle rod preferably has an elastic region. More preferably, the elastic region is formed from a material selected from a group comprising: metals and in particular titanium and its alloys, steel or CoCr or plastics and in particular polyethylene, polyurethane, polyetheretherketone, carbon fiber reinforced plastic or superelastic nitinol. This embodiment has the advantage that the mobility of the pedicle rod to the implant can be easily effected.
Furthermore, the implant may have an elastic element which is arranged at a connection region between the implant and the pedicle rod. This embodiment has the advantage that an additional stabilization can be achieved by the use of a damping element. For this purpose, z. For example, a hollow cylinder of polycarbonate urethane (PCU) may be placed in the cavity between the implant and pedicle rod, the shape and geometry of which may be varied to selectively determine the extent of damping and stabilization.
In a preferred embodiment, the implant has a threaded anchor in the lumen and the pedicle rod has a threaded portion whereby a firm but releasable connection between the implant and pedicle rod can be achieved. Furthermore, other joining techniques such. As bonding, clamping, welding, snapping or locking possible.
In addition, a uniaxial, a biaxial or a polyaxial articulation between the implant and the pedicle rod may be provided, whereby the mobility, in particular the flexion and extension of the pedicle rod to the implant can be easily effected.
In the case of the holding device for vertebral bodies, it has proved to be advantageous if, in the posterior region, the implant has a stop surface and the pedicle rod has an abutment counter surface for limiting the mobility between the implant and the pedicle rod.
The pedicle rod preferably has a secondarily closable rod receptacle in the posterior direction. In this context, it has proven to be particularly advantageous if the rod holder comprises an adjustable blocking element. This embodiment has the advantage that the production of a stable-angle connection is possible secondarily via a percutaneous procedure and z. B. in critical bone conditions, an ingrowth of the implants is made possible without load. If the ingrowth is done, z. B. percutaneously closed in local anesthesia dorsal connection, whereby the dynamic or rigid segmental stabilization is activated.
In a vertebral body retainer according to the present invention, it is advantageous if the pedicle rod has an oval cross-section. Due to the oval cross section, the range of motion for flexions and / or extensions can be increased while maintaining stability. Due to the oval cross-section, the moment of resistance can be different in different levels, so that z. B. the inflection easier possible as the lateral bend. Furthermore, this increases the stability during rotations.
It is particularly advantageous if the implant is designed with a posteriorly decreasing wall thickness.
Preferably, in the vertebral body retainer, the implant has an extension portion posteriorly on one side which is configured for permanent attachment of a connector connected to a second retainer to a coupling means, in particular to a connector retainer. This embodiment is particularly suitable for multi-segment dynamic applications. In order to achieve full dynamics, in particular in the case of flexion / extension, over several segments, it is necessary to compensate for the length changes which occur in the area of the dorsal connecting elements, so that the movabilities of the individual segments can add up. The connection between the individual dynamic holding devices is such that in each case the pedicle rod of a holding device with the next cranial implant (sleeve) is connected to the extension portion via the coupling means. This allows an arbitrarily long stabilization can be achieved. This advantage can be achieved according to the present invention for a dorsal fixation system with a number of such holding devices, characterized in that at least the first holding device comprises a connecting element via a fixing part of the first holding device with the pedicle bar of the first holding device and the coupling means of the second holding device is connected to the second holding device.
According to a second aspect of the present invention, this object is achieved in a dorsal fixation system in that a first holding device for vertebral bodies according to one of the above embodiments and a second holding device for vertebral bodies is provided with a connecting element having a first attachment part with the first Pedikelstab the Having the first holding device and a second fastening part with the second pedicle rod of the second holding device. This embodiment has the advantage that a better segment mobility is effected by the physiologically placed center of rotation in the dorsal portion of the vertebral body. This allows the system z. B. also be used as a disc prosthesis. In addition, a combination with a facet joint replacement is possible at a later stage.
Preferably, in the dorsal fixation system, the first attachment member and / or the second attachment member are configured to stably maintain a first angle between the connector and the first pedicle rod of the first holder and a second angle between the connector and the second pedicle rod of the second holder.
Alternatively, in the dorsal fixation system, the first attachment member and / or the second attachment member may be configured to variably hold a first angle between the connector and the first pedicle rod of the first holder and a second angle between the connector and the second pedicle rod of the second holder.
In the case of the dorsal fixation system, it has proved to be advantageous if the connecting element has a telescopic area and / or a flexible area in order to compensate for the length changes occurring in the region of the dorsal connecting elements.
The dorsal fixation system preferably has a third holding device for vertebral bodies, and the connecting element is connected to a third pedicle rod of the third holding device via a third fastening part on the third holding device. In this way, a multi-segment dynamic stabilization can be achieved.
Another advantage of the fixation system according to the invention is that a segment distraction is possible via the dorsal connecting element in order, for. B. continuously relieve the intervertebral disc.
1 a cross-sectional view of a vertebral body support device of the spine according to a first embodiment of the present invention,
2 a cross-sectional view of a vertebral body support device of the spine according to a second embodiment of the present invention,
3 a cross-sectional view of a vertebral body support device of the spine according to a third embodiment of the present invention,
4 FIG. 2 is a cross-sectional view of a vertebral body spine retainer according to a fourth embodiment of the present invention; FIG.
5 a cross-sectional view similar to the 1 to 4 with inhibited degrees of freedom according to a conventional holding device,
6 a cross-sectional view of a Pedikelstabes with a posterior connecting element,
7 a cross-sectional view of a dorsal fixation system with a first vertebral body support device of the spine and a second vertebral body support device of the spine according to a first embodiment of the present invention,
8th a cross-sectional view of a dorsal fixation system for multi-segmental applications according to a second embodiment,
9 a cross-sectional view of a dorsal fixation system with a flexible connecting element according to a third embodiment,
10 a schematic representation of the movement possibilities of a dorsal fixation system,
10a one opposite 10 further abstracted representation of the dorsal fixation system at rest,
10b one of the 10a corresponding representation in the state deflected due to movement,
11 a cross-sectional view of a dorsal fixation system according to a fourth embodiment,
12 a cross-sectional view of a dorsal fixation system according to a fifth embodiment, and
13 a cross-sectional view of a dorsal fixation system according to a sixth embodiment.
1 shows a holding device 20a vertebral body of the spine according to a first embodiment of the present invention. The holding device 20a includes an implant 1 with a cavity 3 and a pedicle stick 2 , The implant 1 has a threaded anchorage 4 on, in which a threaded section 5 of the pedicle rod 2 can be introduced, with a diameter of 4 mm to 5 mm for the threaded portion 5 of the pedicle rod 2 has proved to be advantageous. Furthermore, the implant 1 have a conical basic shape with an external thread, wherein the front threaded portion may be designed to be blunt, to allow a bicortial anchoring. In the rear area, the external thread can become increasingly flatter and cutting to avoid blasting the pedicle. Preferably, the surface of the implant is coated. The wall thickness of the implant 1 may be posteriorly decreasing. The implant 1 can be introduced and anchored transpedicularly in the lumbar vertebrae from the posterior, with a sleeve-shaped configuration of the implant 1 has proved to be advantageous. The anchoring in the vertebral body may be via the surface structure (such as thread or coating) and / or via a change in shape of the implant 1 (such as spreading, compression or ballooning) take place.
The pedicle stick 2 continues to have a dynamic range 12 , an anchoring area 14 and a motion limitation area 13 on, in which the attachment of a stop counter surface 7 of the pedicle rod 2 on a stop surface 6 of the implant 1 the movement is limited. Thus, the implant 1 and the pedicle stick 2 formed in the posterior region so that there is a movement limitation in the desired frame. In order to determine the permissible range of motion targeted, appropriate embodiments of the stop surface 6 of the implant 1 and the stop counter surface 6 of the pedicle rod 2 to get voted.
In order to be able to better adapt the extent of the dynamics and the turning center to patient-specific requirements, the pedicle bar can be used 2 in the dynamic range 12 have different diameters and / or different configurations. In the in the 1 shown holding device 20a according to the first embodiment, the pedicle rod 2 in the dynamic range 12 one compared to the threaded portion 5 substantially the same diameter, wherein in the first embodiment of the dynamic Area 12 of the pedicle rod 2 to the threaded section 5 of the pedicle rod 2 is arranged adjacent. In the description of the further embodiments of the following figures is to be noted that the same elements are provided with the same reference numerals and that to avoid repetition for the following embodiments, only the differences will be discussed.
2 shows a holding device 20b vertebral body of the spine according to a second embodiment of the present invention, wherein the pedicle rod 2 in the dynamic range 12 one compared to the threaded portion 5 having reduced diameter, wherein in the second embodiment, the dynamic range 12 of the pedicle rod 2 to the threaded section 5 of the pedicle rod 2 is arranged adjacent.
3 shows a holding device 20c vertebral body of the spine according to a third embodiment of the present invention, wherein the pedicle rod 2 in the dynamic range 12 one compared to the threaded portion 5 having reduced diameter, wherein in the third embodiment between the dynamic range 12 of the pedicle rod 2 and the threaded portion 5 of the pedicle rod 2 one on the implant 1 adjacent reinforcement area 17 arranged with enlarged diameter.
4 shows a holding device 20d vertebral body of the spine according to a fourth embodiment of the present invention, wherein the pedicle rod 2 in the dynamic range 12 one compared to the threaded portion 5 having reduced diameter, wherein in the fourth embodiment, the dynamic range 12 of the pedicle rod 2 at the threaded portion 5 of the pedicle rod 2 is arranged adjacent and wherein additional an elastic element 10 between the dynamic range 12 of the pedicle rod 2 and the implant 1 is arranged.
By means of different embodiments of the dynamic range, an optimal adaptation to the special needs of the respective patients can thus take place. Furthermore, a rigid pedicle rod may be included in the system to allow for secondary change from dynamic stabilization to rigid stabilization or to allow a secondary change from rigid stabilization to dynamic stabilization.
For a better understanding of the present invention is in the 5 a conventional holding device 200 shown for vertebral bodies of the spine. The conventional holding device 200 includes an implant 1 and a pedicle stick 2 , wherein neither a dynamic range nor a Bewegungsbegritierungsbereich are formed, so that only a rigid anchorage can take place.
6 shows a cross-sectional view of a Pedikelstabes 2 with a posterior connecting element 11 for connection with another pedicle rod, wherein the connecting element 11 is preferably formed as a connecting rod. The pedicle stick 2 has posterior a closable rod holder 8th for the connecting element 11 on. To activate the connection, a blocking element 9 be provided for activating the connection in the in the 6 shown arrow direction can be moved.
7 shows a cross-sectional view of a dorsal fixation system 50 with a first holding device 21 for vertebral bodies of the spine according to the present invention and a second holding device 22 vertebral body of the spine according to the present invention with a connecting element 11 that is a first fastening part 15a for attachment to a first pedicle rod 2a the first holding device 21 and that a second attachment part 15b for attachment to a second pedicle rod 2 B the second holding device 22 having. Alternatively, it is also possible in the dorsal fixation system according to the present invention that the first holding device 21 or the second holding device 22 by a in the 7 not shown conventional vertebral body support device is replaced with a rigid Pedikelstab. In this way a combination of rigid and dynamic stabilization can be achieved.
Furthermore, in the in the 7 embodiment shown, the dorsal fixation system 50 in the first holding device 21 a first turning center 16a and in the second holding device 22 a second center of rotation 16b on. The first attachment part 15a and / or the second fastening part 15b may be configured, a first angle α between the connecting element 11 and the first pedicle stick 2a the first holding device 21 or a second angle β between the connecting element 11 and the second pedicle rod 2 B the second holding device 22 stable. Alternatively, the first attachment part 15a and / or the second fastening part 15b be configured, the first angle α between the connecting element 11 and the first pedicle stick 2a the first holding device 21 or the second angle β between the connecting element 11 and the second pedicle rod 2 B the second holding device 22 variable.
Further, in the dorsal fixation system according to the present invention, the number of spinal vertebral body retainers is not limited to two, but more retainer devices may be used.
8th shows a cross-sectional view of a dorsal fixation system 50b for multi-segment applications according to a second embodiment with three holding devices 21 . 22 . 23 , The holding devices 21 . 22 . 23 each have a pedicle rod 2a . 2 B . 2c on, on each of which a connecting element 11a . 11b . 11c via a corresponding fastening part 15a . 15b . 15c is appropriate. Furthermore, the first and the second connecting element 11a . 11b with the next cranial implant by coupling agent 18 at the posterior extension sections 17 of the corresponding implants 1 connected. In this embodiment, the physiological centers of rotation are located 31a . 31b . 31c near the mechanical turning centers 16a . 16b . 16c ,
9 shows a cross-sectional view of a dorsal fixation system 50c with a flexible connecting element according to a third embodiment. The structure is similar to that in 7 shown embodiment, wherein the connecting element 11 a telescopic area 19 and a flexible area 30 in this case by a taper in the connecting element 11 is formed.
In the 10 a schematic representation of the possibilities of movement of the dorsal fixation system in monosegmentaler instrumentation is shown. In addition to the rotational movement indicated by arrows, a translation is also possible. In addition, the separation of the implant and pedicle rod can reduce possible screw loosening, since the dynamic movements are not transmitted via a bone-implant interface but via the implant-pedicle rod interface. Furthermore, a distraction takes place dorsally over the pedicle rods and the longitudinal member, whereby the dynamics (range of motion) is maintained. In addition, a kyphosis can be avoided, so that an active influence of the sagittal profile is possible without affecting the range of motion.
11 shows a cross-sectional view of a dorsal fixation system 50d according to a fourth embodiment, in which a physiological center of rotation 31 caudal near the mechanical turning center 16 of the implant is located. Thus, a rigid connection element 11 possible and it can be used for the second and third holding device conventional holding devices, since no additional mobility is necessary. Thus, the dorsal fixation system includes 50d according to the fourth embodiment, one and two conventional holding devices according to the invention.
12 shows a cross-sectional view of a dorsal fixation system 50e according to a fifth embodiment, in which the physiological center of rotation 31 far away from the mechanical center of rotation 16 is located, so that a second movement is necessary. This requires a dynamic connector 11 , Like in the 12 This can be demonstrated by a flexible area 30 be reached, the z. B. is formed by a taper. Again, the dorsal fixation system includes 50e according to the fifth embodiment, one and two conventional holding devices according to the invention.
13 shows a cross-sectional view of a dorsal fixation system 50f according to a sixth embodiment with three holding devices according to the invention, in which the three physiological centers of rotation 31a . 31b . 31c caudal near the three mechanical turning centers 16a . 16b . 16c are located. In contrast to a monosegmentalen instrumentation, in which two ranges of motion are sufficient to cause flexion and translation, in the present multi-segment instrumentation further movement areas are necessary, which in the in the 13 present embodiment are designed as a taper.
Pedikelstab
first pedicle stick
second pedicle rod
third pedicle rod
Thread anchoring in the implant
Thread section of the pedicle rod
Stop surface of the implant
Abutment surface of the pedicle rod
lockable rod holder
third connecting element
RLD area
first fastening part
second fastening part
third fastening part
first mechanical turning center
second mechanical turning center
third mechanical turning center
first posterior extension section
second posterior extension section
third posterior extension section
telescopic area of the connecting element
Holding device according to the first embodiment
Holding device according to the second embodiment
Holding device according to the third embodiment
Holding device according to the fourth embodiment
first holding device
second holding device
third holding device
physiological center of rotation
flexible area of the connecting element
first physiological center of rotation
second physiological center of rotation
third physiological center of rotation
dorsal fixation system according to a first embodiment
dorsal fixation system according to a second embodiment
dorsal fixation system according to a third embodiment
dorsal fixation system according to a fourth embodiment
dorsal fixation system according to a fifth embodiment
dorsal fixation system according to a sixth embodiment
conventional holding device
first angle between the connecting element and the first Pedikelstab
second angle between the connecting element and the second Pedikelstab
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies of the spine having an implant to be introduced into a vertebral body ( 1 ) and a pedicle stick ( 2 ), characterized in that the implant ( 1 ) for the mobility of the pedicle rod ( 2 ) a cavity ( 3 ) and that the pedicle rod ( 2 ) in the cavity ( 3 ) for a permanent mobility or for a temporary mobility of the pedicle rod ( 2 ) with respect to the implant ( 1 ) is arranged.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to claim 1, characterized in that the implant ( 1 ) has a sleeve-shaped configuration.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to claim 1 or 2, characterized in that the pedicle rod ( 2 ) has an elastic region.
Holding device ( 20a . 20b . 20c . 20d ) according to claim 3, characterized in that the elastic region comprises a material selected from a group comprising: metals and in particular titanium and its alloys, steel, nickel-titanium alloys including nitinol, memory metals , or CoCr or plastics and in particular polyethylene, polyurethane, polyetheretherketone, carbon fiber reinforced plastic.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to claim 3 or 4, characterized in that the implant ( 1 ) an elastic element ( 10 ), which at a connection region between the implant ( 1 ) and the pedicle rod ( 2 ) is arranged.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to one of the preceding claims 3 to 5, characterized in that the implant ( 1 ) a threaded anchorage ( 4 ) in the cavity ( 3 ) and the pedicle rod ( 2 ) a threaded portion ( 5 ) having.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to claim 1 or 2, characterized in that a uniaxial or a multi-axis articulation between the implant ( 1 ) and the pedicle rod ( 2 ) is provided.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to one of the preceding claims, characterized in that in the posterior region the implant ( 1 ) a stop surface ( 6 ) and the pedicle rod ( 2 ) a stop counter surface ( 7 ) for limiting the mobility between the implant ( 1 ) and the pedicle rod ( 2 ) exhibit.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to one of the preceding claims, characterized in that the pedicle rod ( 2 ) a secondary closable rod receptacle ( 8th ) having.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to claim 9, characterized in that the rod receptacle ( 8th ) an adjustable blocking element ( 9 ).
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to one of the preceding claims, characterized in that the pedicle rod ( 2 ) has an oval cross-section.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to one of the preceding claims, characterized in that the implant ( 1 ) is formed with a posteriorly decreasing wall thickness.
Holding device ( 20a . 20b . 20c . 20d ) for vertebral bodies according to one of the preceding claims, characterized in that the implant ( 1 ) posteriorly on one side an extension section ( 17 ), which is for a permanent Attachment of a with a second holding device ( 20a . 20b . 20c . 20d ) connected connecting element ( 11 ) with a coupling agent ( 18 ) is configured.
Dorsal fixation system ( 50b ) with a number of holding devices ( 21 . 22 . 23 ) for vertebral bodies according to claim 13, characterized in that at least the first holding device ( 21 ) a connecting element ( 11 ), which via a fastening part ( 15a ) of the first holding device ( 21 ) with the pedicle rod ( 2a ) of the first holding device ( 21 ) and via the coupling agent ( 18b ) of the second holding device ( 22 ) with the second holding device ( 22 ) connected is.
Dorsal fixation system ( 50a . 50c . 50d . 50e . 50f ) with a first holding device ( 21 ) for vertebral bodies according to one of claims 1 to 12 and a second holding device ( 22 ) for vertebral bodies, characterized by a connecting element ( 11 ), which is a first fastening part ( 15a ) with the first pedicle rod ( 2a ) of the first holding device ( 21 ) and a second fastening part ( 15b ) with the second pedicle rod ( 2 B ) of the second holding device ( 22 ) having.
Dorsal fixation system ( 50a . 50c . 50d . 50e . 50f ) according to claim 13, characterized in that the first fastening part ( 15a ) and / or the second fastening part ( 15b ) are configured, a first angle (α) between the connecting element ( 11 ) and the first pedicle rod ( 2a ) of the first holding device ( 21 ) or a second angle (β) between the connecting element ( 11 ) and the second pedicle rod ( 2 B ) of the second holding device ( 22 ) stable.
Dorsal fixation system ( 50a . 50c . 50d . 50e . 50f ) according to claim 13, characterized in that the first fastening part ( 15a ) and / or the second fastening part ( 15b ) are configured, a first angle (α) between the connecting element ( 11 ) and the first pedicle rod ( 2a ) of the first holding device ( 21 ) or a second angle (β) between the connecting element ( 11 ) and the second pedicle rod ( 2 B ) of the second holding device ( 22 ) variable.
Dorsal fixation system ( 50a . 50c . 50d . 50e ) according to one of claims 15 to 17, characterized in that the connecting element ( 11 ) a telescopic area ( 19 ) and / or a flexible area ( 30 ) having.
Dorsal fixation system ( 50a . 50c . 50d . 50e ) according to one of claims 15 to 18, characterized in that it comprises a third holding device ( 23 ) for vertebral bodies and that the connecting element ( 11 ) via a third fastening part ( 15c ) on the third holding device ( 23 ) with a third pedicle rod ( 2c ) of the third holding device ( 23 ) connected is.
DE201010016854 2010-05-10 2010-05-10 Retaining device for vertebral bodies of the spine Withdrawn DE102010016854A1 (en)
DE201010016854 DE102010016854A1 (en) 2010-05-10 2010-05-10 Retaining device for vertebral bodies of the spine
US12/869,977 US9119671B2 (en) 2010-05-10 2010-08-27 Fixation assembly for spinal vertebrae
TW100108209A TWI544895B (en) 2010-05-10 2011-03-11 The spinal vertebral body holding means
ES11161088.7T ES2584037T3 (en) 2010-05-10 2011-04-05 Retention device for vertebral bodies of the spine
EP11161088.7A EP2386258B1 (en) 2010-05-10 2011-04-05 Holding device for spine vertebrae
MX2011004699A MX2011004699A (en) 2010-05-10 2011-05-04 Holding device for spine vertebrae.
RU2011118235/14A RU2549529C2 (en) 2010-05-10 2011-05-05 Fixing device for body of vertebral column vertebra
CN201110131406.XA CN102240222B (en) 2010-05-10 2011-05-10 Retaining means for the spinal vertebrae
JP2011105558A JP5705017B2 (en) 2010-05-10 2011-05-10 Retention brace for spine vertebral body
BRPI1102461-5A BRPI1102461A2 (en) 2010-05-10 2011-05-10 spinal body fixation device
DE102010016854A1 true DE102010016854A1 (en) 2011-11-10
DE201010016854 Withdrawn DE102010016854A1 (en) 2010-05-10 2010-05-10 Retaining device for vertebral bodies of the spine
BR (1) BRPI1102461A2 (en)
MX (1) MX2011004699A (en)
TW (1) TWI544895B (en)
FR2924014B1 (en) 2007-11-22 2010-01-22 Henry Graf Device for connecting at least three vertebrates between them
2010-05-10 DE DE201010016854 patent/DE102010016854A1/en not_active Withdrawn
2010-08-27 US US12/869,977 patent/US9119671B2/en not_active Expired - Fee Related
2011-03-11 TW TW100108209A patent/TWI544895B/en active
2011-04-05 EP EP11161088.7A patent/EP2386258B1/en active Active
2011-04-05 ES ES11161088.7T patent/ES2584037T3/en active Active
2011-05-04 MX MX2011004699A patent/MX2011004699A/en active IP Right Grant
2011-05-05 RU RU2011118235/14A patent/RU2549529C2/en not_active IP Right Cessation
2011-05-10 CN CN201110131406.XA patent/CN102240222B/en not_active IP Right Cessation
2011-05-10 JP JP2011105558A patent/JP5705017B2/en not_active Expired - Fee Related
2011-05-10 BR BRPI1102461-5A patent/BRPI1102461A2/en not_active IP Right Cessation
RU2549529C2 (en) 2015-04-27
JP2011235104A (en) 2011-11-24
CN102240222A (en) 2011-11-16
TW201138711A (en) 2011-11-16
MX2011004699A (en) 2011-11-18
BRPI1102461A2 (en) 2012-10-16
JP5705017B2 (en) 2015-04-22
ES2584037T3 (en) 2016-09-23
US9119671B2 (en) 2015-09-01
EP2386258B1 (en) 2016-06-22
TWI544895B (en) 2016-08-11
RU2011118235A (en) 2012-11-10
EP2386258A1 (en) 2011-11-16
US20110276094A1 (en) 2011-11-10
CN102240222B (en) 2016-11-16
ES2310906T3 (en) 2009-01-16 Device for fixing the vertebral column.