Source: http://healthdocbox.com/Nutrition/68538508-Ec-number-cas-number-support-document-for-identification-of-as-a-substance-of-very-high-concern-because-of-its-cmr-1-properties.html
Timestamp: 2018-12-10 16:32:14
Document Index: 385161189

Matched Legal Cases: ['art 3', 'art 3', 'art 3', 'art 3', 'art 3', 'art 3', 'art 3', 'art 3', 'art 3', 'art 3', 'art 3', 'art 2']

EC Number: CAS Number: SUPPORT DOCUMENT FOR IDENTIFICATION OF AS A SUBSTANCE OF VERY HIGH CONCERN BECAUSE OF ITS CMR 1 PROPERTIES - PDF
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1 Substance Name: N-methylacetamide EC Number: CAS Number: SUPPORT DOCUMENT FOR IDENTIFICATION OF N-METHYLACETAMIDE AS A SUBSTANCE OF VERY HIGH CONCERN BECAUSE OF ITS CMR 1 PROPERTIES 1 CMR means carcinogenic, mutagenic or toxic for reproduction
3 CONTENTS 1 IDENTITY OF THE SUBSTANCE AND PHYSICAL AND CHEMICAL PROPERTIES NAME AND OTHER IDENTIFIERS OF THE SUBSTANCE COMPOSITION OF THE SUBSTANCE HARMONISED CLASSIFICATION AND LABELLING ENVIRONMENTAL FATE PROPERTIES HUMAN HEALTH HAZARD ASSESSMENT ENVIRONMENTAL HAZARD ASSESSMENT CONCLUSIONS ON THE SVHC PROPERTIES CMR ASSESSMENT... 8 TABLES Table 1: Substance identity... 5 Table 2: Constituents... 6 Table 3: Classification according to part 3 of Annex VI, Table 3.1 ((list of harmonised classification and labelling of hazardous substances) of Regulation (EC) No 1272/ Table 4: Classification according to part 3 of Annex VI, Table 3.2 (list of harmonized classification and labelling of hazardous substances from Annex I of Council Directive 67/548/EEC) of Regulation (EC) No 1272/
4 Substance Name: N-methylacetamide EC Number: CAS number: The substance is identified as substance meeting the criteria of Article 57 (c) of Regulation (EC) 1907/2006 (REACH) owing to its classification as toxic for reproduction 1B 2 which corresponds to classification as toxic for reproduction category 2 3. Summary of how the substance meets the criteria set out in Article 57 (c) of REACH (Repr. 1B). N-methylacetamide is listed as Index number in Regulation (EC) No 1272/2008 and classified in Annex VI, part 3, Table 3.1 (list of harmonised classification and labelling of hazardous substances) as toxic for reproduction, Repr. 1B (H360D ***: May damage the unborn child. ). The corresponding classification in Annex VI, part 3, Table 3.2 (the list of harmonised classification and labelling of hazardous substances from Annex I to Directive 67/548/EEC) of Regulation (EC) No 1272/2008 is toxic for reproduction, Repr. Cat. 2, R61 ( May cause harm to the unborn child. ). Therefore, this classification of N-methylacetamide in Regulation (EC) No 1272/2008 shows that the substance meets the criteria for classification as toxic for reproduction in accordance with Article 57 (c) of REACH. Registration dossiers submitted for the substance? Yes 2 Classification in accordance with Regulation (EC) No 1272/2008 Annex VI, part 3, Table 3.1 List of harmonised classification and labelling of hazardous substances. 3 Classification in accordance with Regulation (EC) No 1272/2008, Annex VI, part 3, Table 3.2 List of harmonised classification and labelling of hazardous substances (from Annex I to Council Directive 67/548/EEC). 4
5 JUSTIFICATION 1 Identity of the substance and physical and chemical properties 1.1 Name and other identifiers of the substance Table 1: Substance identity EC number: EC name: N-methylacetamide CAS number (in the EC inventory): CAS number: Deleted CAS numbers: CAS name: IUPAC name: Index number in Annex VI of the CLP Regulation Molecular formula: Molecular weight range: Synonyms: Acetamide, N-methyl- N-Methylacetamide C 3 H 7 NO 73.1 g/mol Monomethylacetamide Methylacetamide Structural formula: C H 3 NH CH3 O 5
6 1.2 Composition of the substance Name: N-methylacetamide Description: --- Degree of purity: % Table 2: Constituents Constituents N-methylacetamide Typical concentration Concentration range Remarks % According to the information available in the registration dossiers 6
7 2 Harmonised classification and labelling N-methylacetamide is listed as Index number in Annex VI, part 3 of Regulation (EC) No 1272/2008 as follows: Table 3: Classification according to part 3 of Annex VI, Table 3.1 ((list of harmonised classification and labelling of hazardous substances) of Regulation (EC) No 1272/2008 Index No International Chemical Identification EC No CAS No Classification Labelling Spec. Hazard Class and Category Code(s) Hazard statement code(s) Pictogr am, Signal Word Code(s N-methylacetamide Repr. 1B H360D *** GHS08 Dgr Hazard statement code(s) H360D *** Suppl. Hazard statement code(s) Conc. Limits, M-factors Notes Table 4: Classification according to part 3 of Annex VI, Table 3.2 (list of harmonized classification and labelling of hazardous substances from Annex I of Council Directive 67/548/EEC) of Regulation (EC) No 1272/2008 Index No International Chemical Identification EC No CAS No Classification Labelling Concentration Limits N-methylacetamide Repr. Cat. 2; R61 T R: 61 S: Notes 7
8 3 Environmental fate properties Not relevant for the identification of the substance as SVHC in accordance with Article 57(c). 4 Human health hazard assessment See section 2 on harmonised classification and labelling. 5 Environmental hazard assessment Not relevant for the identification of the substance as SVHC in accordance with Article 57(c). 6 Conclusions on the SVHC Properties 6.1 CMR assessment N-methylacetamide is listed as Index number in Regulation (EC) No 1272/2008 and classified in Annex VI, part 3, Table 3.1 (list of harmonised classification and labelling of hazardous substances) as toxic for reproduction, Repr. 1B (H360D ***: May damage the unborn child. ). The corresponding classification in Annex VI, part 3, Table 3.2 (the list of harmonised classification and labelling of hazardous substances from Annex I to Directive 67/548/EEC) of Regulation (EC) No 1272/2008 is toxic for reproduction, Repr. Cat. 2, R61 ( May cause harm to the unborn child. ). Therefore, this classification of N-methylacetamide in Regulation (EC) No 1272/2008 shows that the substance meets the criteria for classification as toxic for reproduction in accordance with Article 57 (c) of REACH. 8
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