Source: https://patents.google.com/patent/WO2005032352A1/en
Timestamp: 2019-05-24 17:31:32
Document Index: 744922880

Matched Legal Cases: ['art 27', 'art 36', 'art 36', 'art 36', 'art 36', 'art 36', 'art 3', 'art 36', 'art 36']

WO2005032352A1 - Digestive tract interior examination instrument - Google Patents
WO2005032352A1
WO2005032352A1 PCT/JP2004/013028 JP2004013028W WO2005032352A1 WO 2005032352 A1 WO2005032352 A1 WO 2005032352A1 JP 2004013028 W JP2004013028 W JP 2004013028W WO 2005032352 A1 WO2005032352 A1 WO 2005032352A1
PCT/JP2004/013028
2003-09-30 Priority to JP2003-342417 priority
2004-09-08 Application filed by Olympus Corporation filed Critical Olympus Corporation
2005-04-14 Publication of WO2005032352A1 publication Critical patent/WO2005032352A1/en
The digestive tract interior examination instrument comprises a capsule endoscope capable of examining a digestive tract, a flexible tube, a flexible string-like member passed through the tube, and a connecting section disposed in the capsule endoscope. The tube and the capsule endoscope are separably connected by removably connecting the string-like member to the connecting section.
Gastrointestinal tract inspection equipment
[0001] The present invention relates to a digestive tract inspection apparatus suitable for performing the gastrointestinal tract examination.
[0002] For the inspection of a body cavity, various capsule medical apparatus has been proposed. For example, as the first conventional example, the Japanese Kohyo 2001- 526072, JP-inserted together with the attached flexible tube endoscopic capsule while held by the clamp means, the capsule holding at the target site release devices have been disclosed.
Clamping means is of a shape obtaining 垤 the outer shape of the capsule, the outer diameter of the holding state is greater than the capsule Le single outside diameter.
[0003] Further, as the second conventional example, Japanese Patent Publication No. PCT International Publication No. WO01Z89596A2, and held by suction capsule at the far end of the tube is filled with a liquid with a proximal end and a distal end, at the target site device for opening the capsule to release the suction is disclosed.
Further, as a third conventional example, Japanese Patent 2003 The 135,388 discloses, fitted with a needle with the tube body of the double pipe structure to the rubber stopper at the rear end of the capsule-out with a balloon, the connection between the capsule when releasing a device for storing it is disclosed a needle small diameter portion into the barrel of the double tube.
While [0004] is a force, a conventional example of the first to third has the following disadvantages.
In the first conventional example, it means that swallow capsules being held by the clamp means, is poor swallowing ease of subjects than drinking capsule itself.
Further, when inserting the capsule into the body, at the same time because also inserted endoscope with the flexible tube, it takes effort and preparing the endoscope cleaning after use of the insertion assisting endoscope. Further, there is a drawback such that it is necessary to perform pretreatment such as local anesthesia necessary for the endoscope inserted into the subject.
[0005] In the second conventional example, since the holding portion for holding by suction the capsule thicker than the capsule out of shape, worse than when swallowing ease during swallowing capsules drink only capsules alone. Since when releasing the 吸弓 I capsule deviates, observed in a capsule with a cloth dispersed dye staining solution and the like in the esophagus (dye observed) lines were, in such case, observation flame, drawbacks etc. Mel.
In yet a third conventional example, during removal of the double tube after uncoupling, it is necessary to note that not withdrawn while the needle double tube is exposed without being completely housed. Also, since the capsule when removing the inner needle is out, further perform dye observation flame.
[0006] Accordingly, the present invention is both a good insertability or removal of the subject, in a simple manner, the inspection and detailed in the above side gastrointestinal tract, and more untethered inspection in the deep side and to provide a preferred capable gastrointestinal tract inspection apparatus.
More specifically [0007], and to provide retraction and inspection in the esophagus, the capsule in the digestive tract inspection device allowing implementation both untethered inspection deep side of the stomach force. Further, the present invention is a insertional or removal properties Yogu easy way to a subject, wide from near cardia!, Providing the capsule in the digestive tract inspection apparatus for gastric inspection range and feasible also an object of the present invention to.
Furthermore, the present invention is, insertional or removal of the subject's Yogu easily, to provide a capsule of the gastrointestinal tract inspection apparatus capable dye test at a desired location in the esophagus (the stain test) it is also of interest.
[0008] gastrointestinal tract inspection apparatus of the present invention, a test capsule endoscope in the digestive tract,
A flexible tube body,
A string-like member of flexible to be inserted into the tube member,
A connecting portion provided in the capsule endoscope,
By detachably coupling the string-like member to the connecting portion, characterized by detachably connecting the tube member and the capsule endoscope
With the above configuration, in a state of connecting the cord-like member inserted through the tube member to the capsule endoscope, or inspected in detail by setting the speed suitable for the digestive tract to the inspection, the bow when necessary I You can return and be or inspection, by releasing the connection at the connecting portion for the further depth side, enabling inspection by the capsule endoscope untethered state of being disengaged with the tube body to easily It is way.
[1] Mel Figure 1 is a general block diagram of a capsule endoscope system having a first embodiment of the present invention.
FIG. 2 is a basic overall configuration diagram of the capsule in the digestive tract inspection apparatus.
FIG. 3 is a diagram showing a detailed configuration of the capsule in the digestive tract inspection apparatus.
[4] FIG 4 is a diagram showing a configuration of a distal end portion of the gastrointestinal tract inspection apparatus.
FIG. 5 is a diagram showing an example configuration of a tube and the like.
FIG. 6 is a diagram showing a use example and inspection methods.
[7] FIG. 7 is a flowchart showing a procedure of a representative test method.
[8] FIG. 8 is a diagram showing the structure of a digestive tract inspection apparatus according to a second embodiment of the present invention.
[9] Figure 9 is a diagram showing a main part of a configuration of the gastrointestinal tract inspection apparatus according to a third embodiment of the present invention
[10] FIG 10 is Mel a diagram showing a main part of a configuration of the gastrointestinal tract inspection apparatus according to a fourth embodiment of the present invention.
[11] FIG 11 is a diagram showing a configuration of a main part of the gastrointestinal tract inspection apparatus of the first modification.
[12] FIG 12 is a diagram showing a configuration of a main part of the gastrointestinal tract inspection apparatus of the second modification.
[13] FIG 13 is Mel a diagram showing a main part of a configuration of the gastrointestinal tract inspection apparatus of the fifth embodiment of the present invention.
[14] FIG 14 is a diagram showing a configuration of a main part of the gastrointestinal tract inspection apparatus according to a modification.
[15] Figure 15 is Mel a diagram showing a main part of a configuration of the gastrointestinal tract inspection apparatus according to a sixth embodiment of the present invention.
[16] Mel in FIG 16 showing the configuration of a main part of the gastrointestinal tract inspection apparatus of Embodiment 7 of the present invention.
[17] Mel in Figure 17 showing a configuration of a main part of the gastrointestinal tract inspection apparatus of Embodiment 8 of the present invention. BEST MODE FOR CARRYING OUT THE INVENTION
[0010] Hereinafter, with reference to the accompanying drawings illustrating the embodiment of the present invention.
[0011] Referring to FIGS. 1A to 7 for explaining a first embodiment of the present invention.
[0012] The present embodiment is carried out to improve the insertability and withdrawal of the subject, in a simple manner, retraction and inspection in the esophagus, both untethered inspection in deeper side from the stomach becomes possible, furthermore, it aims to provide a desired capsule in the digestive tract inspection apparatus and inspection method that enables dye inspection at the position of the esophagus.
[0013] capsule endoscope system 1 provided with the first embodiment of the present invention as shown in Figure 1A, the body cavity duct by being swallowed from the mouth of a patient 2 as a subject, specifically, when passing through the gastrointestinal tract, the capsule endoscope transmits the image signal of the captured gut wall optically wirelessly (hereinafter, capsules for short) and 3, via the string member 6 in the capsule 3 having a gastrointestinal tract inspection device 5 consists of a tube body 4 which connects removably Te.
[0014] Also, the capsule endoscope system 1, the signals transmitted by the capsule 3 is received via the antenna unit 7 provided outside the patient 2, a function of storing the image (patient 2 is disposed outside the body) external unit 8 is also provided, Ru.
Further, the external unit 8 as shown in FIG. 1B, a personal computer (hereinafter, PC hereinafter) 11, is detachably connected, for example by a USB cable 12 or the like of the cable. The personal computer 11 includes a personal computer 13 having a built-in hard disk for recording a CPU and image, is connected to the personal computer 13, a keyboard 15 for performing a Disupu ray 14 as a display means for displaying an image, a data input, etc. There has been connected. Then, accumulated in the external unit 8, save the image to a hard disk of the personal computer 13, the image stored in the viewing in the display 14! /, Ru.
[0015] As medical practice swallow capsule 3 as shown in FIG. 1 A, for example, when performing endoscopy, Antenayu knit 7 in which a plurality of antennas 17 are attached is attached to the patient 2 wears shirt 16 that. Captured by the capsule 3, also the transmitted signal antenna power incorporated in it, this is received by the antenna unit 7, so as to store the image captured by the antenna unit 7 external unit 8 connected to the Ru . Further, the extracorporeal unit 8, a liquid crystal monitor 18 is provided with, and to be able to display images transmitted from the capsule 3. The external unit 8 is for example mounted by detachably hooks wear of the belt patient 2.
2 with the external unit 8 shows the basic structure of the gastrointestinal tract inspection device 5. Capsule As shown in FIG. 2. 3, the one end portion and the outer member body 21 which is closed by a hemispherical shape cylindrical fitting fixed hemispherical shaped transparent to the other open end of the exterior member main body 21 in the cover 22, the interior thereof is the external container of the watertight are formed.
[0016] This is the inside of the transparent cover 22 in the outer container is disposed an optical image it image the (objective) optical system 23 of the observation object, a shooting image of CMOS imagers such as, for example, is in its image forming position imaging device 24 is arranged to perform, Ru.
Also, inside the transparent cover 22, adjacent to the optical system 23, for example, irradiation light portion 25 such as a white LED is disposed, the imaging range to be imaged on the image pickup element 24 by the optical system 23 (observation range) It is to illuminate.
On the back side of the imaging device 24, drives the illumination unit 25, a control circuit 26 for driving and signal processing and control of the image pickup device 24, a wireless transmission to transmit the image signal picked up by the image pickup device 24 to the external unit 8 part 27, power supply 28 and the like are arranged by the battery for supplying power for operating the respective circuits or the like. The wireless transmission section 27 is connected to an antenna (not shown).
[0017] Further, the rear end comprising a transparent cover 22 in the exterior member main body 21 and opposite, Yes through hole 29 having a function of coupling portion coupling the tube body 4 is provided, the string in the through-holes 29 by passing the member 6, the capsule 3 through the cord-like member 6 is detachably attached to the tube body 4 itself standing (separable ヽ said releasable) is connected to.
In other words, by inserting the two cord-like member 6 which is folded in a state where the folded portion through a through hole 29 of the cord-like member 6 in the hollow portion of the tube body 4, the body, in particular in the gastrointestinal tract Ru so as to be inserted the capsule 3 which is connected to the tube member 4.
[0018] Then, illuminated by the illumination unit 25 provided in the capsule 3, the illuminated imaging a wall surface or the like in the optical system 23 and the imaging device 24 among rows endoscopic examination ヽ, the captured image information outside the body the transmitted wirelessly by the external unit 8 disposed outside the body, the images information endoscopy obtained in the capsule 3 through the antenna unit 7, so as to be accumulated! /, Ru. The external unit 8 includes a wireless receiver 31 connected to the antenna unit 7 (the antennas 17), with respect to the signal demodulated by receiving this radio reception section 31 performs AZD conversion and compression processing, etc. a control circuit 32, a storage unit 33 for storing the image signal is compressed through the control circuit 32, and a power supply 34 for supplying power to the control circuit 32 and other circuits. The control circuit 32 is connected to the display processing circuit 35 performs display processing for displaying on the liquid crystal monitor 18 the image transmitted from the capsule 3. The user, the image displayed on the liquid crystal monitor 18, Rukoto to monitor the image captured by the image sensor 24 of the capsule 3 in Strain 〖as monkey! /, Ru.
Figure 3 shows a more detailed overall structure of gastrointestinal tract inspection device 5.
[0019] flexible tube body 4 as shown in Figure 3, the folded portion through the through hole 29 of the capsule 3 in the vicinity of the tip opening is formed, a string-like member 6 which is folded back by the folded portion by 揷通 the hollow portion of the tube member 4 is connected to the capsule 3 and the tube body 4. Rear end of the tube member 4 is connected by a tube body proximal portion 36 and the soluble Chakumatawa adhesive or the like which branches into a generally V-shaped, Ru.
The tube body proximal part 36, a extending hollow portion 37 that extends as a hollow section and linearly coupling the tube body 4, the branch hollow portion 38 pointed to be the hollow portion that branches obliquely on the way It has been made.
The extending hollow portion 37 is used 揷通 etc. string member 6, the branch hollow portion 38 has a function of a syringe insertion port for inserting the tip of the syringe 39, 40 detachably.
[0020] Further, in the vicinity of the rear end of the extending hollow portion 37, the plug shape becomes a string member holding means for holding the 揷通 state cord-like member 6 which is inserted by the close of the opening member 41 is provided integrally with the tubular body proximal section 36 manner, for example.
Moreover, also the branch hollow portion 38, that in the vicinity of the rear end, is provided with plug-like member 42 to close this opening integrally with the tubular body proximal part 36 for example, Do using a syringe 39, 40 , in the case so as to be closed by the WASH member 42, Ru.
One observation was dyed into the syringe 39 (inspection) is for the dye, for example, Yodo 1. about 5% Yodo solution 43 is housed for staining observed stained by using this syringe 39 as it is, Ru.
[0021] Further, the other syringe 40, Yes put clear liquid 44 such as clean water, by using the syringe 40, or wash the dyed dyes, clean also wash mucus and bubbles It is way.
In Figure 3, although shows a state linked to the capsule 3 by the string-like member 6 which is inserted into the tube member 4, FIG. 4A- 4C illustrate the steps of operation for connecting the capsule 3.
As shown in FIG. 4A, the insertion jig 45 such as a wire to the distal end of the cord-like member 6 in advance by fixing pre Me with tape or the like, the insertion jig 45 by 揷通 the hollow portion of the tube member 4 , easily string member 6 can inserted into the hollow portion of the tube member 4. The insertion jig 45 which has 揷通 the hollow portion of the tube member 4, further passed through the through hole 29 of the capsule 3.
Through hole 29 in this case, as shown in FIG. 4B which is a P palm Figure 4A, is notched on either side force for example substantially elliptic engaging portion 46 for locking the cord-like member 6 of the central portion was that has become a shape. After the operation through the through hole 29 as shown in FIG. 4A or FIG. 4B, by passing the insertion tool 45 from the distal end of again tube member 4 in its hollow portion, the tube body 4 as shown in FIG. 4C a capsule 3 (which is inserted into the tube body 4) the string assembly in the connected state with member 6 is completed.
In this case, as shown in FIG. 4C, the inner surface 及 Beauty outer surface of the portion forming the distal end opening of the tube member 4 is chamfered portion 4a which is R-chamfered is formed. Further, the engaging portion 46 between the through-hole 29 of the capsule 3 side is formed with R-shaped portion 46a along the through-holes 29 of both sides, in a state where the insertion of the string-shaped member 6, the string-shaped member 6 There was easily move smoothly string member 6 be your ヽ in contact with state on the wall surface of the locking portion 46, Ru.
Figure 5A- FIG. 5D shows an example of the configuration of the tube body 4. Tube member 4 in this embodiment has a flexible, incompressible, good having a bending hardly characteristics even when allowed to act traction cord-like member 6 by the yarn or the like to be inserted . Further, even when the pushing and pulling the tube body 4, easily Do would provide an bending, is good and has a feature.
[0022] The tube member 4 has an outer diameter of less than half of 5mm outer diameter of the capsule 3 (more Nozomu Mashiku is 2-3 mm or so) was inserted to force the body cavity is easy and during insertion such to, desirable to make it easier to drink the patient 2. Further, the tube body 4, the outer diameter of the capsule 3, more about 10mm For example much smaller. Thus, the outer diameter of the tube member 4, the force when fully Hosogu and tube member 4 with respect to the outer diameter, which was driven like in a state of inserting the string member 6 in its hollow portion of the capsule 3 But it is set to have a readily 橈Ma no level of flexibility, Ru. In the example shown in FIG. 5A illustrating a specific configuration example of a tube member 4 with reference to FIGS 5A- FIG 5D shows what the tube member 4, formed in the torque tube 47. The torque tube 47 is Mel in which embedded blade 48a and the like in the flexible tube 48b.
[0023] In addition, the tube member 4 in Fig. 5B, is formed by a coiled member 49a by embedding in the tube 48b. In this case, it may be formed co over preparative layer 49b to improve the sliding properties to the inner and outer surfaces. As the coating film 49b, when employing the full Tsu Motokei 榭脂 such as Teflon (registered trademark), having good sliding properties.
Figure 5C, PTFE (poly tetra Full O b-ethylene), such as PFA (perfluoroalkoxy 榭脂), along with flexibility, to form a tube member 4 in the tube 50 of the resin and fluorine-containing resins having good sliding properties It shows things. In this case, it can be relatively thin.
Further, Figure 5D shows that constitute the tube member 4 in Shioi匕 Bulle and relatively flexible slippery material having good strength even greens Ru thickness 榭脂 tube 51, etc. of urethane (Poirot down tube or the like) . In the above description, the hollow portion of the tube member 4 has been described assuming a single lumen, the two lumens 52a as shown in FIG. 5E, to form a 52 b, Ryoru Men 52a, the string-like member 6 which is folded in 52b may be one Dzu' 揷通.
[0024] Furthermore, it may be changed hardness and 弹発 of tube member 4 partially. For example, other than 10 cm of the tip to hardness' 弹発 potentially avoid bending or easily bent, by only 10cm of the distal opening side flexible than other portions, swallowing operability and patient capsule 3 it is possible to achieve both ease. Change in hardness Ya 弹発 property may be of changing stepwise, it may be continuously changed gradually.
[0025] On the other hand, the string member 6, of desirable tool for example slip properties good Teflon or nylon having a strength in diameter with good sliding properties yarn and, gut, surgical it is possible to use a thread or the like. The length of the tube body 4, even when the capsule 3 has reached the stomach 57, as the rear end of the tube member 4 is external from at least the mouth 53 may be set to more than about 60cm. Further, the string member 6 may be set to more than twice the length of the tube body 4.
Using digestive tract inspection apparatus 5 having such a configuration will be described the operation to inspect the gastrointestinal tract with reference to FIGS. 6A one Figure 6C.
As shown in FIG. 6A, the tube body proximal part 36 of the digestive tract inspection device 5, mounting the syringe 39 has been input to Yodo liquid 43. The end after the tubular body proximal part 36 inserted through the string member 6 prevents such string-like member 6 and the stopper with WASH member 41 resulting in unnecessarily moving,
[0026] Then, the patient 2 swallows the capsule 3 from the neck 53. Le capsule is swallowed from the mouth 53 3, through the throat 54 to move into the esophagus 55 side. The esophagus 55, upper 5 5a which is a throat 54 side, central 55b, and is divided into a lower portion 55c in the vicinity of the cardia 56.
When the capsule 3 alone, capsules 3 which has passed through the throat 54, a short time when it passes through the esophagus 55 will reach the stomach 57 there Ru force present embodiment by peristalsis weight and esophagus 55 of the capsule 3 because it is connected to the tube body 4, according to the example, equal to or pushed and pulled by gripping the rear end of the tube member 4, the rate of the moving speed of the capsule 3 of the tip of the tube member 4 and the desired it is possible to set, and the like that stop at any position in the middle of the esophagus 55, it is also possible to allow inspection more detail.
[0027] Further, it is possible to set the rate of the moving speed of the capsule 3 and desired, in capsule Le 3 shooting speed for example, two Z seconds for taking pictures and less relatively slow speed, so that it is taking the necessary number of sheets.
[0028] For example, in the upper portion 55a of the esophagus 55, if desired, such as examining the inner wall details, in a state in which the capsule 3 as shown in FIG. 6A positioned within the upper 55a, operates the syringe 39 containing the Yodo solution and, Yodo solution to Note entry into the body near the top 55a through the hollow portion of the tube member 4. Yodo liquid 43 injected is sprayed around the capsule 3, 〖Konaru be sprayed on the inner wall surface of the upper 55a.
Thus by spraying Yodo liquid 43 or the like of the dye, images captured by the capsule 3, the structure and the like are stained becomes clearer, it is easy to diagnose. In other words, it is possible to easily perform inspection by the Yodo staining method.
When the imaging by site capsules 3 which were sprayed with the dye by spraying dyes its forward (deeper) side to the capsule 3 is moved to be completed, so as to image further spraying dye Te Gyotsu optionally and it may be.
[0029] Moreover, I Do perform spraying dye, from the top 55a of the esophagus 55 to the bottom 55c in a state, after imaging by moving the capsule Le 3, pulling the capsule 3 pulling the tube member 4 to the top 55a ( pullback) may 〖this to perform imaging by the capsule 3 performs spraying dye in that state.
That is, the inspection and in a status of not staining with dyes, can also easily be inspected repeatedly under different conditions and the inspection in a state subjected to staining by the dye. Since the return Pull is possible, it can be performed or pressing tube member 4, the pulling test of repeatedly changing the moving speed or the like or.
Thus, in this embodiment by connecting the capsule 3 in the tube body 4! /, Runode, by manipulating the proximal end of the tube member 4 outside the body, by setting the capsule 3 in an arbitrary position, re it is also possible to rub 〖to perform degrees imaging.
[0030] In this manner, the imaging inspection of esophagus 55 is finished, the capsule 3 reaches the stomach 57 through the cardia 56.
When checking the stomach 57 in a capsule 3, it may be inspected by a method as shown in Figure 6B. As shown in FIG. 6B, performs pull down the two cord-like member 6 coming out of the tube body proximal part 36 (traction, relaxation) operations and that, the operation of rotating the tube member 4.
This push-pull (traction, relaxation) when operated, projects from the distal end of the tube member 4, pulling down the two cord-like member 6 which is folded back through the through-hole 29 (traction, relaxation) to, 6B the capsule 3 from the state shown by the solid line to the state indicated by the two-dot chain line by rotating the shown Suyo by arrow a, it is possible to extensively test the stomach 57 by changing the viewing direction of.
[0031] In addition, by performing an operation to rotate to twist the tube member 4, the tip of the tube member 4 can also be rotated as shown by arrow B in FIG. 6B, changing the viewing direction in this case the stomach 57 can be extensively tested with. After such check the stomach 57, by pulling only one of the two cord-like member 6, by moving the other hand to the front end side of the tube member 4, engaged by folding as shown in FIG. 6C to release the locked state by detaching the capsule 3 from the string-like member 6, the capsule 3 by Do drop into the stomach 57, it is possible to also detach the tube body 4 force.
Capsule 3 which has fallen into the stomach 57, the peristaltic motion of the stomach 57, so that moves to the duodenum 58 side. Capsule 3 performs imaging for example in a fixed cycle, and sends the captured image data wirelessly transmitted image data is stored in the storage unit 33 of the extracorporeal unit 8. It is also possible to confirm the images captured by the monitor 18.
[0032] In addition, imaging speed of the capsule 3 before and after withdrawal may be the same or may be increased to two Z s force four Z seconds or more before eg withdrawal after withdrawal. When the moving speed of the capsule 3 has decreased rapidly after withdrawal, by increasing the imaging speed, you can shoot the required number. Shooting speed change at the time of withdrawal is carried out by sending a signal of the imaging speed changes from the external unit 8 in the capsule 3 in the body. Alternatively, a built-in timer in the capsule 3 may automatically switch the imaging speed by inspection after the start time (e.g. 10 minutes).
[0033] Representative examples of the test method described above is shown in FIG. The first in the step S1 capsule 3 and the connected state of the tube body 4, down the capsule 3. In the next step S 2, after the capsule cell 3 pharynx pass performs endoscopy (the imaging study) in the capsule 3 at a desired site in the esophagus 55 while operating the traction 'relax tube member 4.
Feeding an extracorporeal power fluid for dyeing Yodo liquid 43 or the like to the tube body 4 in the next step S3, a fluid discharge and (injected 55 side esophagus) in the vicinity of the rear end of the tip Ka ゝ Luo capsule 3 of the tube body 4 to stain the surrounding Te.
In step S4 after release of the fluid, for imaging inspection the stained esophagus 55.
[0034] In yet a next step S5, by manipulating et capsule 3 has reached the stomach 57 after cardia 56 passes, a plurality of the cord-like member 6, the imaging inspection by changing the viewing direction of the capsule 3 I do. Disconnecting the tube 4 and the capsule 3 in the next step 6, extraction of the body only tube member 4 performs imaging study only the capsule 3.
In this way, from the esophagus 55 to the inside the stomach 57 can endoscopy in detail, after the inspection of the stomach 57 can endoscopy capsule 3 itself separately from the tube body 4. According to the present embodiment, in a simple manner, retraction and observation in the esophagus 55 allows implementing both the untethered observed deep from within the stomach 57.
Further, in a simple manner, cardia 56 near power also a wide range of the stomach 57 of observation is feasible. Furthermore, in a simple manner, there is an effect such that it is possible to dye observed at the desired location in the esophagus 55.
[0035] Referring now to FIGS. 8A and 8B illustrating the gastrointestinal tract inspection apparatus according to a second embodiment of the present invention. In Example 1, in the hollow portion of the tube member 4, which had been inserted through the two cord-like member 6 which is folded back, the gastrointestinal tract inspection apparatus 5B of this embodiment, as shown in Figure 8A, the capsule 3 the string-like member 6 which is folded back through transmural hole 29, with a force for example the vicinity of the front end you inserted halfway of the hollow portion of the tube member 4, paste tube member 4 sewn so as to penetrate the side or in the viscous adhesive and so as to form a temporary fixing portion 61 is temporarily fixed by equally.
In this case, it may be caused to pass through the tube member 4 in the vicinity of the distal end of the insertion jig 45 and the needle member attached tube member 4 such as a wire to the distal end of the cord-like member 4 as shown in FIG. 4A advance in advance provided a large number of through-holes in the vicinity of the tip of the tube body 4 may be formed temporary fixing portions 61 equal to temporarily fixed through the easy through-hole FREE Keru inserted into them.
[0036] temporary fixing portions 61 in this case, since it is latched state was attached at or adhesive to the string-shaped member 6 in a loop, cord-like member which has issued the rear end side force extending the tube body 4 the six strong argument Kukoto, as shown in FIG. 8B can eliminate the temporarily fixed state, by further manipulation of pulling the string member 6 rearwardly, set in a state leaving the tube core 4 from the capsule 3 can do.
Further, the rear end of the tube member 4 in this embodiment is a structure without the tube body proximal part 3 6 shown in FIG. 3 or the like. As in Example 1, when observing with dye sprayed it may be to provide a switch Yubu body proximal section 36. Moreover, by press-fitting or the like, even if the tube body proximal part 36 to be releasably attached to the rear end of the tube member 4 good! ヽ. Other configurations in this embodiment are the same as those in Example 1.
[0037] inspection method according to this embodiment can be carried out substantially in the same manner as in Example 1. If you brief, the connected state of the tube member 4 in the capsule 3 in the case of inspecting the inside of the esophagus 55, as shown in FIG. 6A, i.e., to check in the state shown in FIG. 8A.
Then, by checking the esophagus 55, by the capsule 3 performs an operation hauling string member 6 coming out also rear force of the tube body 4 reaches the stomach 57, the above end in the string member 6 it can be removed string member 6 temporary bonding portion on the side. Then, it is possible to leave the tube 4 and the capsule 3.
[0038] Then, by performing an operation to pull the tube member 4, can and this withdrawal of the tube body 4 of the body, and discard the tube body 4. On the other hand, the capsule 3 drops into the stomach 57, then moved by peristalsis to duodenum 58 side, it moves further in peristalsis small intestine, until the large intestine, the capsule 3 when the do imaging. In other words perform an endoscopic examination. Image data captured by the capsule 3 is transmitted wirelessly to the external unit 8, image data transmitted is stored in the storage unit 33 of the extracorporeal unit 8. Further, the liquid crystal monitor 18, leaving at Kotochi to confirm the captured image.
According to this embodiment, it is possible to more reliably leaving the tube body 4 of the capsule 3 by the operation of small pull. Other has almost the same effects as in Example 1. Example 3
[0039] Referring now to FIG. 9D from Figure 9A illustrating the gastrointestinal tract inspection apparatus according to a third embodiment of the present invention.
Gastrointestinal tract inspection apparatus 5C of the present embodiment, as shown in FIGS. 9A and 9B, is a characteristic structure in the vicinity of the through holes 29 definitive capsule 3C. Specific examples of the string member 6 in the present embodiment employs a cutting easily cotton thread 6C. It should be noted that, in addition to the cotton thread 6C, ease fully with downy soft force, such as wool, good in yarn,.
Capsule 3C in this embodiment, the locking portion 46 shown in FIG. 4C in the capsule 3 of Example 1, a portion through a cotton thread 6C in a substantially U shape, projecting portions 46b made of, for example, a sharp portion that the wedge-shaped the provided, Ru.
That, CC section in FIG. 9A, sharp protrusions 46b are formed as shown in FIG. 9B.
[0040] Accordingly, in the state of FIG. 9A, one more to performing strongly pulling operation cotton thread 6C, by cutting cotton thread 6C with projections 46b as shown in FIG. 9C, the tube member 4 side cotton it can be detached the thread 6C and the capsule 3C. Withdrawal capsules 3 drops downward. Other configurations are the same as in Embodiment 1 or Embodiment 2.
Effect of this embodiment is substantially the same as in Example 2 and the like. That is, the user performs an operation to pull strongly cotton thread 6C, easily leave in the Rukoto disengages the tube member 4 side and the capsule 3C.
Incidentally, in this embodiment, may have a cross-sectional shape as forces interchanged these cross-sectional shape that is the configuration shown in FIG. 9B a CC section of Figure 9A. For example, to form a sharp protrusion 46b to the engaging portion 46 as shown in FIG. 9D sectional shape of FIG. 9A, in this CC cross-sectional shape when in the structure Do, as appears sharp protrusions 46b also good! ,.
[0041] Next you explain gastrointestinal tract inspection apparatus of the fourth embodiment of the invention with reference to FIGS. 10A and 10B. Gastrointestinal tract inspection apparatus 5D of this embodiment includes a tube body 4 string member 6 is inserted, the tube body 4 is also capsule 3D and force coupled via the string member 6.
The capsule 3D, instead of providing a rear end through hole 29 of the exterior member main body 21 for example in the first embodiment, the recess 63 is formed, the resilient member 6 5 provided a through hole 64 is accommodated in the recess 63 , and is fixed with an adhesive 66 (or press fit), etc., Ru.
The elastic member 65 is formed of, for example, urethane or silicone rubber or the like, the through hole 64 is provided on the outer surface forces near distance, the thin portion 65a is made form the thick portion has decreased thinner. When the strong force is applied to the thin portion 65a, the thin portion 65a is configured to fracture. Other configurations are the same as in example Example 2.
[0042] inspection method according to this embodiment can be carried out as in Example 2. Then, the present embodiment, since the effect of the case of separating the tube member 4 side and the capsule 3D is different, the operation in the case of that.
In this embodiment, as shown in FIG. 10A, in a state where the cord-like member 6 into the through hole 64 of the elastic member 65 is communicated transmural, the string-like member 6 of the two inserted through the tube member 4 rearward by performing strongly pulling that operation, it is possible to break the thin portion 65a of the elastic member 65 as shown in FIG. 10B. This fracture, 〖be separate from the tube member 4 side and the capsule 3D, the capsule 3D falls Konaru.
Effect of this embodiment is substantially the same as that of Example 2. [0043] FIG 11A illustrates a gastrointestinal tract inspection apparatus 5E of the first modification. Capsule Le 3E in this modification, the recess 67 substantially in the same manner as the capsule 3D in FIG. 10A are formed. However, the recess 67 is formed in a tapered shape that the opening end side becomes wider.
Then, this recess 67, is inserted string member 6 folded in a U-shape, after insertion of the cord-like member 6, the elastic upper force like also the rubber plug 68 of the folded portion of the string-like member 6 by press-fitting member is connected to the tube member 4 side and the capsule 3E.
In the present modified example, by performing an operation to pull strongly string member 6 rearwardly, the rubber stopper 68 is press-fitted into the recess 67 as shown in FIG. 11B, it is the this disengaging from the recess 67 It is way. Others have the same effect as in Example 3.
[0044] In this modification, the upper force of the string member 6 accommodated in the recess 67 is also pressed with a rubber stopper 68
. In this state, that is through hole formed in the concave portion 67 and the rubber plug 68 as shown in FIG. 11A.
In contrast, as in the digestive tract inspection apparatus 5F of the second modification shown in FIGS. 12A and 12B, connected by state-like through-holes are not formed even when press-fitting the rubber plug 70 into the recess 69 of the capsule 3F also good as can be,.
In this modification, as shown in FIG. 12A, the capsule 3F, the recess 6 9 are formed as the capsule 3E. The recess 69 is one of the inner surface of the recess 69 is flat, concave and convex portion 69a is formed on an inner surface opposed to the flat surface. The D-D cross section of FIG. 12A shown in FIG. 12B.
[0045] string-like member 6 and the rubber stopper is folded into a loop and inserted into the tube member 4 in the recess 69
By 70 and is pressed, it is to be connected to the tube body 4 side and the capsule 3F.
In this case, the rubber stopper 70 is a state of being compressed in the bottom of the recess 69, so that the protruding portion 70a that protrudes to the upper side folded string member 6 side is formed.
Therefore, by performing an operation to pull the string member 6 to the rear side, the rubber plug 70 with the string member 6, the bottom power of the concave portion 69 also to move to the upper side.
In this case, the recess 69 so uneven portion 69a is formed in the depth direction of the recess 69, can feel at Kurittsuku sense the movement of the pitch of the uneven portion 69a when pulled. In the case of FIGS. 12A and 12B, after the click feeling had twice can grasp that can be removed with further pulling. Other effects are substantially the same as in Example 3. Example 5
[0046] Referring now to FIG. 14 from FIG. 13A illustrating the gastrointestinal tract inspection apparatus of the fifth embodiment of the present invention. As shown in FIGS. 13A and 14B, gastrointestinal tract inspection device 5G of the present embodiment, two transmural hole 29a, and the capsule 3G having a 29 b, a tube member 4 having a tip member 71 at the distal end, the tube first and second cord-like member 6a which is inserted in the hollow portion of the body 4, and a 6b. Capsules 3G, for example, in the capsule 3 in the first embodiment, instead of the one through hole 29 to the rear end of the outer member body 21, two through holes 29a, 29b are symmetrically formed on both sides of the observation center axis O those were. Incidentally, the observation center axis O, for example coincides with the optical axis of the capsule 3G internal optical system 23. Also shows the observation range of the optical system 23 by reference numeral theta. Tip member 71 attached to the tip of the tube body 4 is a larger outer diameter, for example, rotationally symmetric shape than the outer diameter of the tube member 4, the a tip portion, there is provided a protruding portion 73 of substantially hemispherical shape .
[0047] Then, in the vicinity of the foot of a substantially hemispherical shape of the projection portion 73 of the tip member 71, the two through holes 29a, at a position opposed to the 29 b, two so as to communicate with the hollow portion of the tube member 4 opening 71a of, 71b are provided.
Then, it is inserted through the hollow portion of the tube member 4, an opening 71a provided in the tip member 71, the cord-like member 6a that protrudes from 71b, 6b, the through hole 29a of the opposing capsule 3G, folded back through 29b Te is connected to the re-opening 71a, the tube core 4 so as to be 揷通 the hollow portion of the tube body 4 through the 71b and the capsule 3G.
In this embodiment, the first and second cord-like member 6a, the state set equal 牽 attraction on the capsule 3G side by 6b, hemispherical shaped protrusions 73 of the tip member 71 as shown in FIG. 13A in contact with the rear end of the outer member body 21 the front end of the protrusion 73 is on the observation center axis O, it can be set in a substantially linear shape from the tube 4 and the capsule 3G.
[0048] In contrast, the first and second cord-like member 6a, by relatively changing the tractive force on the capsule 3G side by 6b, from the longitudinal direction of the tube body 4 as shown in FIG. 13B so that it is possible to tilt the direction of observation center axis O of the capsule 3G. The user, for example, loosening the first string member 6a as shown in FIG. 13B, by pulling the second cord-like member 6 b, bent in the second string member 6b side was driven by the capsule 3G or it can be set to be inclined. Thus pulling one of the first string member 6a and the second cord-like member 6b, by relaxing the other, the capsule 3G by 傾力 can variably set the observation center axis O direction.
[0049] Then, has a wide range of directions to be imaging study. Thus, for example, it within the stomach 57 as described in FIG. 6B, Te, Ru can check the inner walls of the stomach 57 extensively. Also in the esophagus 55 by performing an operation as shown in FIG. 13B, it is also possible to change the viewing direction to check more detail. Others have approximately same as effects as in Example 1 and Example 2, and the like.
[0050] It may also be a digestive tract inspection device 5H according to the first modification shown in FIG. 14. In this variant Katachirei, two lumens 52a showing the tube member 4 in FIG. 5E example, formed by a double-lumen tube having a 52 b, each lumen 52a, the first and second cord-like member 6a from 52 b, and 6b are protruded through hole 29a of the capsule 3G, it can be linked through 29b. Further, the center of the distal end surface of the tube body 4, the protrusion 75 of the hemispherical is provided. Then, the protrusion 75 is brought into contact with the rear end surface of the capsule 3G, one of the traction of the first string member 6a and the second cord-like member 6b, by relaxing the other, the direction of observation capsule 3G the as it is variably set, Ru.
The case of the first modification has substantially the same action and effect as the present embodiment. As this modification, two lumens 52a, instead 〖This 52 b, or as digits set four lumens.
[0051] Referring now to FIG. 15 illustrating the gastrointestinal tract inspection apparatus according to a sixth embodiment of the present invention. Gastrointestinal tract Ken查 device 51 of this embodiment, in FIG. 14 for example, two lumens 52a, instead of 52b, as well as four Noremen 52a ゝ 52a 'ゝ 52b ゝ 52b', without providing the protrusion 咅the liquid injection lumen 76 in the tube member 4 provided. Note that the rear end of the tube body 4, is connected to those similar to the tube body proximal part 36 described in Example 1, to inject liquid medicine Yodo solution or therapeutic through the liquid injection lumen 76 it is obtained by allow.
[0052] Referring now to FIG. 16 illustrating the gastrointestinal tract inspection apparatus of Embodiment 7 of the present invention. Gastrointestinal tract inspection device 5J according to this embodiment is composed of a capsule Le 3J of the through-hole 77 is provided near the proximal end of the transparent cover 22, a tube member 4 string member 6 is 挿痛. The through hole 77 is close to approximately the diameter of the capsule 3J, is formed to penetrate the part.
The string-like member 6 which is inserted through the tube member 4, by passing through holes 77 digits set to the capsule 3J from the distal end opening of the tube member 4 is connected via the string member 6 and the tube 4 and the capsule 3J .
In this case, the through hole 77, since the longitudinal direction of the formed in a near ヽ positioned at the front end side provided a transparent cover 22 than the center Ru capsule 3J, the cord-like member and the tube member 4 and the capsule 3J 6 in the state of being connected, in a state where the transparent cover 22 is opposed to the tube member 4 side. The through hole 77 is formed on the outside of the observation field theta.
This embodiment, viewing direction (imaging direction) is opposite to that in Example 1, and the like. Except that observation direction is different, it has substantially the same effects as in Example 1 and Example 2, and the like.
[0053] Next you explain gastrointestinal tract inspection apparatus of Embodiment 8 of the invention with reference to FIGS. 17A and 17B. Gastrointestinal tract inspection device 5K according to this embodiment is composed of a tube member 4 for the transparent cover 22a at both ends, and the force capsule 3K provided with 22b, first and second cord-like member 6a, 6b is inserted .
And an inner transparent cover 22a, on the inner side of the transparent cover 22b and the optical system 23 and the image pickup device 24 shown in FIGS 2 and illumination unit 25 is disposed. Also shows an observation range by the optical system at 0.
The transparent cover 22a, the exterior member main body 21 of the position close to the proximal end of the 22b, respectively through holes 77a, 77b are is provided with first and second cord-like member 6a, respectively, 6b is Ru is inserted.
[0054] describing the inspection method according to the present embodiment with reference to FIGS. 17A and 17B. Close to the outer diameter of the capsule 3K as the esophagus 55 as shown in FIG. 17A, in the case of inspecting the inside of the tube cavity portion, the first and second longitudinal capsule 3K is along the longitudinal direction of the lumen 2 of cord-like members 6a, manipulating 6b.
For example, by pulling stronger than the first string member 6a second cord-like member 6b, is set to the state shown in FIG. 17 A, it is possible to inspect the esophagus 55.
In contrast, in the case of inspecting a much larger stomach 57 compared to the size of the capsule 3K, by equalizing the traction force by the first string member 6a and the second cord-like member 6b, It can be set to landscape orientation as shown in FIG. 17B.
[0055] After observation in this state, for example by pulling stronger than the first string member 6a second string member 6b, it is possible to tilt the capsule 3K as shown by two-dot chain line. By operating in this way the traction of the first string member 6a and the second cord-like member 6b, can be tested by changing wide viewing direction in the stomach 57.
Other effects are the same as like in Example 1.
Also belonging to the present invention examples and the like formed by combining the respective embodiments or the like described above in part. In the embodiments described above have been described in the case where the optically imaging study (endoscopy), and spraying or when pharmacists for inspecting other than optical in pH sensing Ya ultrasonic inspection It can be applied to a case such as performing medical procedures for treatment.
[0056] the connecting portion of the through hole or the like of the capsule endoscope, and thoroughly inspected the gastrointestinal tract of the esophagus or the like in the body cavity while connected through the cord-like member that 揷通 the tube body, then ligated releasing the deep-side inspection also performed in the capsule endoscope alone.
[1] and the test capsule endoscope in the digestive tract,
Wherein by a string-like member is detachably connected to the connecting portion, gastrointestinal tract inspection apparatus characterized by detachably connecting the tube member and the capsule endoscope.
[2] The coupling portion is a through hole provided in the capsule endoscope, to be detachably coupled to the capsule endoscope and the tube member by 揷通 the string-shaped member into the through hole gastrointestinal tract inspection apparatus in the range 1 wherein according to said.
[3] The coupling portion includes a recess provided in the capsule endoscope consists of a possible fitting member fitted in the recess, the lower cell by locking the cord-like member in the recess by the fitting member range 1 Kouki placing the gastrointestinal tract inspection apparatus according to, characterized in that detachably connects the endoscope and the tube member.
[4] the outside diameter of the tube body, the digestive tract inspection apparatus in the range 1 claim of claim you being not more than half the outer diameter of the capsule endoscope.
[5] digestive tract inspection apparatus in the range 4 claim of claim, wherein the outer diameter of the tube body is 5mm or less.
[6] the tube body, the digestive tract in the range 4 claim of claim, characterized in that it comprises a 橈Ma no flexibility to easily even force when pulling while inserting the cord-like member therein inspection
[7] gastrointestinal tract examination device according ranging preceding claims, characterized in that the end portion of the cord-like member equipped with a holding means for detachably holding the vicinity of the proximal end of the tube body.
[8] The one end of the string-shaped member detachably fixed by fixing part provided in the middle of the tube body via a connecting portion provided at the other end of the cord-like member in the capsule endoscope gastrointestinal tract inspection apparatus in the range 1 claim of claim, characterized in that inserted to the distal end forces the proximal end of the tube body.
[9] the digestive tract inspection apparatus in the range 8 claim of claim, characterized in that one end of the cord-like member is detachably fixed at a fixed portion provided near the distal end of the tube body.
[10] according binomial claims, characterized in that the sharp portion cleavable string-like member by tensioning Hikitsu with a force above a certain level the a string member provided on the periphery of the through hole digestive tract inspection
[11] The force expires by pulling with a force above a certain level the a cord-like member into the through-hole peripheral portion or range 2 the preceding claims, characterized in that a thin portion being detached from the through-hole peripheral portion, gastrointestinal tract inspection apparatus according.
[12] The string member by pulling a constant force or more in the digestive tract inspection apparatus in the range 3 claim of claims fitting portion is fitted in the recess, characterized in that the falling off from the recess.
[13] The tube body gastrointestinal tract inspection apparatus claims one of claims, characterized in that the tip outer surface provided with a chamfer of approximately R shape.
[14] gastrointestinal tract inspection apparatus in the range 1 wherein according to the tube body, characterized in that a separate tip member having a substantially hemispherical portion at the tip of the tube body.
[15] gastrointestinal tract inspection apparatus range one of claims claims, characterized in that to soften the hardness of the distal end side from the proximal side of the tube body.
[16] The tube body gastrointestinal tract inspection apparatus of the tip side having a certain length of the hardness of the stated range 15 of claims, characterized in that was soft Rakakushi than other portions of the tube body.
[17] Range 15 Koki mounting of the digestive tract inspection apparatus according to, characterized in that the hardness of the tube body is continuously changed.
[18] The tube body gastrointestinal tract inspection apparatus in the range 1 wherein according to the fluid inlet, characterized in that provided in the vicinity of the proximal end of the tube body for injecting a liquid or gas
[19] the provided plurality in a position leaving the through-hole, pull the at least one end of the proximal end forces the string-shaped member of the tube body cord-like member a plurality of which is 揷通 the respective through holes are inserted into the tube body gastrointestinal tract inspection system in the range 2 claim of claim, characterized in that the.
[20] The plurality of string-shaped member traction separately 'By loosening operation, according Item 19 claims, characterized in that to constitute a capsule endoscope so as to be swung digestive tract inspection instrumentation
[21] gastrointestinal tract inspection apparatus in the range 19 claim of claim, characterized in that Maruchiru an member tube having a number more than the number of lumens of the string member using said tube body.
[22] digestive tract inspection equipment ranging one of claims claims, wherein said tube member is a multi-lumen tube having a number of lumens of more than twice the number of the string member to be used.
[23] the tube body, or superior torque tube rotational force transmitting properties with embedded metal mesh or metal helix in 榭脂, Teflon that combines slip resistance and hardness and PTFE soil fluoric 榭脂or tube made of the digestive tract inspection apparatus in the range 1 claim of claim, which is a thick 榭脂 tube.
[24] The string member is fluorine-based 榭脂, nylon yarn, surgical thread, according 1, wherein claims, characterized in that gut a yarn having strength even in small diameter with good sliding properties such as digestion pipe inspection
[25] The string member is cotton yarn, silk, polyester yarn, gastrointestinal tract inspection apparatus in the range 10 claim of claim, wherein the yarn is soft and easy to cut the yarn, such as.
[26] a step of the capsule endoscope and a flexible tube tube body connected by flexible string-like member disposed within the flexible tube,
A step of swallowing the concatenated capsule endoscope,
After pharyngeal pass endoscope capsule and performing desired endoscopy site in the esophagus while towing 'relaxed operating the tube body,
Pull the flexible string-shaped member at a desired position, the inspection method comprising the disconnect the tube body and the capsule endoscope.
[27] a step of the capsule endoscope and a flexible tube tube body connected by flexible string-like member disposed within the flexible tube,
After the capsule endoscope is passed through the pharynx and performing endoscopy food canal while pushed or pulled the tube body, feeding a fluid into the tube from the outside, the capsule endoscope from the distal end of the tube body a step of releasing the fluid in the vicinity of the rear end of,
And performing endoscopy in the esophagus after fluid discharge,
[28] the steps of a capsule endoscope and a flexible tube member connected by a plurality of flexible string-shaped member disposed within the flexible tube,
A step swallowing flexible tube body and the concatenated capsule endoscopy, after the capsule endoscope is passed through the pharynx or the cardia, and operate the plurality of string-shaped member, the capsule endoscope and the step of changing the field of view direction,
Pull the flexible string-shaped member at a desired position, comprising the steps of withdrawing only the body away tube body off the tube body and the capsule endoscope,
Inspection method with.
[29] after the step of disconnecting the tube body and the capsule endoscope and performing endoscope inspection in capsule endoscopy alone,
Test method in the range 26 claim of claim, characterized in that it comprises a.
PCT/JP2004/013028 2003-09-30 2004-09-08 Digestive tract interior examination instrument WO2005032352A1 (en)
JP2003-342417 2003-09-30
EP20040787711 EP1671575B1 (en) 2003-09-30 2004-09-08 Digestive tract interior examination instrument
WO2005032352A1 true WO2005032352A1 (en) 2005-04-14
JP2006142081A (en) 2006-02-28 2006-06-08 Samii Kk Slot machine
2003-09-30 JP JP2003342417A patent/JP3993550B2/en active Active
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EP1671575B1 (en) 2015-05-13
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