Source: http://www.google.com/patents/US8188688?dq=alibre+inassignee:alibre
Timestamp: 2015-08-02 11:39:51
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Matched Legal Cases: ['application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61', 'application No. 61']

Patent US8188688 - Magnetic field control method and apparatus used in conjunction with a ... - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsThe invention comprises a charged particle beam acceleration, extraction, and/or targeting method and apparatus used in conjunction with charged particle beam radiation therapy of cancerous tumors. Novel design features of a synchrotron are described. Particularly, turning magnets, edge focusing magnets,...http://www.google.com/patents/US8188688?utm_source=gb-gplus-sharePatent US8188688 - Magnetic field control method and apparatus used in conjunction with a charged particle cancer therapy systemAdvanced Patent SearchPublication numberUS8188688 B2Publication typeGrantApplication numberUS 12/545,815Publication dateMay 29, 2012Filing dateAug 22, 2009Priority dateMay 22, 2008Also published asUS8614554, US8637818, US20090309520, US20120209052, US20120242257Publication number12545815, 545815, US 8188688 B2, US 8188688B2, US-B2-8188688, US8188688 B2, US8188688B2InventorsVladimir BalakinOriginal AssigneeVladimir BalakinExport CitationBiBTeX, EndNote, RefManPatent Citations (110), Non-Patent Citations (23), Referenced by (10), Classifications (8), Legal Events (3) External Links: USPTO, USPTO Assignment, EspacenetMagnetic field control method and apparatus used in conjunction with a charged particle cancer therapy system
US 8188688 B2Abstract
The invention comprises a charged particle beam acceleration, extraction, and/or targeting method and apparatus used in conjunction with charged particle beam radiation therapy of cancerous tumors. Novel design features of a synchrotron are described. Particularly, turning magnets, edge focusing magnets, concentrating magnetic field magnets, winding and control coils, flat surface incident magnetic field surfaces, and extraction elements are described that minimize the overall size of the synchrotron, provide a tightly controlled proton beam, directly reduce the size of required magnetic fields, directly reduces required operating power, and allow continual acceleration of protons in a synchrotron even during a process of extracting protons from the synchrotron.
U.S. provisional patent application No. 61/055,395 filed May 22, 2008; U.S. provisional patent application No. 61/137,574 filed Aug. 1, 2008; U.S. provisional patent application No. 61/192,245 filed Sep. 17, 2008; U.S. provisional patent application No. 61/055,409 filed May 22, 2008; U.S. provisional patent application No. 61/203,308 filed Dec. 22, 2008; U.S. provisional patent application No. 61/188,407 filed Aug. 11, 2008; U.S. provisional patent application No. 61/188,406 filed Aug. 11, 2008; U.S. provisional patent application No. 61/189,815 filed Aug. 25, 2008; U.S. provisional patent application No. 61/201,731 filed Dec. 15, 2008; U.S. provisional patent application No. 61/205,362 filed Jan. 21, 2009; U.S. provisional patent application No. 61/134,717 filed Jul. 14, 2008; U.S. provisional patent application No. 61/134,707 filed Jul. 14, 2008; U.S. provisional patent application No. 61/201,732 filed Dec. 15, 2008; U.S. provisional patent application No. 61/198,509 filed Nov. 7, 2008; U.S. provisional patent application No. 61/134,718 filed Jul. 14, 2008; U.S. provisional patent application No. 61/190,613 filed Sep. 2, 2008; U.S. provisional patent application No. 61/191,043 filed Sep. 8, 2008; U.S. provisional patent application No. 61/192,237 filed Sep. 17, 2008; U.S. provisional patent application No. 61/201,728 filed Dec. 15, 2008; U.S. provisional patent application No. 61/190,546 filed Sep. 2, 2008; U.S. provisional patent application No. 61/189,017 filed Aug. 15, 2008; U.S. provisional patent application No. 61/198,248 filed Nov. 5, 2008; U.S. provisional patent application No. 61/198,508 filed Nov. 7, 2008; U.S. provisional patent application No. 61/197,971 filed Nov. 3, 2008; U.S. provisional patent application No. 61/199,405 filed Nov. 17, 2008; U.S. provisional patent application No. 61/199,403 filed Nov. 17, 2008; and U.S. provisional patent application No. 61/199,404 filed Nov. 17, 2008; claims the benefit of U.S. provisional patent application No. 61/209,529 filed Mar. 9, 2009; claims the benefit of U.S. provisional patent application No. 61/208,182 filed Feb. 23, 2009; claims the benefit of U.S. provisional patent application No. 61/208,971 filed Mar. 3, 2009; and claims priority to PCT patent application serial No.: PCT/RU2009/00015, filed Mar. 4, 2009, all of which are incorporated herein in their entirety by this reference thereto. BACKGROUND OF THE INVENTION
T. Norimine, et. al. “Particle Therapy System Apparatus”, U.S. Pat. Nos. 7,060,997 (Jun. 13, 2006); T. Norimine, et. al. “Particle Therapy System Apparatus”, 6,936,832 (Aug. 30, 2005); and T. Norimine, et. al. “Particle Therapy System Apparatus”, 6,774,383 (Aug. 10, 2004) each describe a particle therapy system having a first steering magnet and a second steering magnet disposed in a charged particle beam path after a synchrotron that are controlled by first and second beam position monitors.
Y. Muramatsu, et. al. “Medical Particle Irradiation Apparatus”, U.S. Pat. No. 7,030,396 (Apr. 18, 2006); Y,. Muramatsu, et. al. “Medical Particle Irradiation Apparatus”, U.S. Pat. No. 6,903,356 (Jun. 7, 2005); and Y,. Muramatsu, et. al. “Medical Particle Irradiation Apparatus”, U.S. Pat. No. 6,803,591 (Oct. 12, 2004) all describe a medical particle irradiation apparatus having a rotating gantry, an annular frame located within the gantry such that is can rotate relative to the rotating gantry, an anti-correlation mechanism to keep the frame from rotating with the gantry, and a flexible moving floor engaged with the frame is such a manner to move freely with a substantially level bottom while the gantry rotates.
The invention comprises a charged particle beam acceleration, extraction, and/or targeting method and apparatus used in conjunction with charged particle beam radiation therapy of cancerous tumors.
In one example, the initial cross-section distance 810 is about fifteen centimeters and the final cross-section distance 820 is about ten centimeters. Using the provided numbers, the concentration of the magnetic field is about 15/10 or 1.5 times at the incident surface 670 of the gap 510, though the relationship is not linear. The taper 860 has a slope, such as about 20 to 60 degrees. The concentration of the magnetic field, such as by 1.5 times, leads to a corresponding decrease in power consumption requirements to the magnets.
Referring now to FIG. 11, an example is used to clarify the magnetic field control using a feedback loop 1100 to change delivery times and/or periods of proton pulse delivery. In one case, a respiratory sensor 1110 senses the breathing cycle of the subject. The respiratory sensor sends the information to an algorithm in a magnetic field controller 1120, typically via the patient interface module 150 and/or via the main controller 110 or a subcomponent thereof. The algorithm predicts and/or measures when the subject is at a particular point in the breathing cycle, such as at the bottom of a breath. Magnetic field sensors 1130, such as the high precision magnetic field sensor 1050, are used as input to the magnetic field controller, which controls a magnet power supply 1140 for a given magnetic field 1150, such as within a first turning magnet 410 of a synchrotron 130. The control feedback loop is thus used to dial the synchrotron to a selected energy level and deliver protons with the desired energy at a selected point in time, such as at the bottom of the breath. More particularly, the synchrotron accelerates the protons and the control feedback loop keeps the protons in the circulating path by synchronously adjusting the magnetic field strength of the turning magnets. Intensity of the proton beam is also selectable at this stage. The feedback control to the correction coils allows rapid selection of energy levels of the synchrotron that are tied to the patient's breathing cycle. This system is in stark contrast to a system where the current is stabilized and the synchrotron deliver pulses with a period, such as 10 or 20 cycles second with a fixed period.
Referring again to FIG. 10, an example of a winding coil 1030 that covers four turning magnets 410, 420, 430, 440 is provided. As described, supra, this system reduces space between turning section allowing more magnetic field to be applied per radian of turn. A first correction coil 1010 is illustrated that is used to correct the magnetic field for the first turning magnet 410. Individual correction coils for each turning magnet are preferred and individual correction coils yield the most precise and/or accurate magnetic field in each turning section. Particularly, the individual correction coil 1010 is used to compensate for imperfections in the individual magnet of a given turning section. Hence, with a series of magnetic field sensors, corresponding magnetic fields are individually adjustable in a series of feedback loops, via a magnetic field monitoring system 1030, as an independent coil is used for each turning section magnet. Alternatively, a multiple magnet correction coil 1020 is used to correct the magnetic field for a plurality of turning section magnets.
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