Source: https://patents.google.com/patent/US20070066998A1/en
Timestamp: 2018-07-16 03:25:08
Document Index: 488390643

Matched Legal Cases: ['art 106', 'art 106', 'art 106', 'art.\n12', 'art.\n13', 'art.\n15', 'art.\n16', 'art.\n23', 'art.\n24', 'art.\n26']

US20070066998A1 - Multi-site lead/system using a multi-pole connection and methods therefor - Google Patents
US20070066998A1
US20070066998A1 US11230989 US23098905A US2007066998A1 US 20070066998 A1 US20070066998 A1 US 20070066998A1 US 11230989 US11230989 US 11230989 US 23098905 A US23098905 A US 23098905A US 2007066998 A1 US2007066998 A1 US 2007066998A1
US11230989
US8731659B2 (en )
Referring again to FIG. 4A, lead proximal end portions 114A, 114B of leads 104A, 104B, respectively, are coupled to cardiac sensor/stimulator 102 via multi-pole connector cavities 402 of header 116, which is affixed to a hermetically sealed housing 412. Hermetically sealed housing 412 may be formed from a conductive metal, such as titanium, and carries electronic components (i.e., circuits, modules, and devices) of cardiac sensor/stimulator 102 (see, e.g., FIG.3). In this example, header 116 includes an indifferent header electrode 414 and housing 412 includes an indifferent housing electrode 416.
Although not shown in FIGS. 4A, 5A, or 6A, other dispositions of the one lead distal end 118 of lead 104 within, on, or about heart 106 are also possible. In one example, at least one lead distal end 118 is transarterially inserted into left atrium 408 or left ventricle 410. In another example, at least one lead distal end 118 is inserted into a pulmonary outflow tract of heart 106. In yet another example, at least one lead distal end 118 is implanted epicardially (i.e., attached to an outer surface of heart 106). In sum, the leads, systems, and methods described herein are adapted to work in a variety of electrode configurations and with a variety of electrical contacts or electrodes.
a lead body extending from one lead proximal end portion to one lead distal end portion and having an intermediate portion therebetween;
at least three tissue sensing/stimulation electrodes disposed along the lead body;
at least three terminal connections disposed along the lead proximal end portion; and
at least three conductors contained within the lead body extending between the tissue sensing/stimulation electrodes and the terminal connections.
2. The lead as recited in claim 1, wherein the tissue sensing/stimulation electrodes are configurable to sense in a first instance and stimulate in a second instance, each by way of one or more tissue electrode configurations.
3. The lead as recited in claim 2, wherein the tissue electrode configurations are selectable, at least in part, from any combination of the tissue sensing/stimulation electrodes.
4. The lead as recited in claim 2, wherein the tissue electrode configurations are selectable, at least in part, from an electrical coupling of two or more tissue sensing/stimulation electrodes.
5. The lead as recited in claim 1, wherein the lead body includes a stylet or guidewire receiving cavity therein, and
at least one preformed biased portion adapted to return to a preformed shape upon removal of a stylet or a guidewire from the stylet or guidewire receiving cavity.
a cardiac sensor/stimulator; and
at least one lead including,
a lead body extending from one lead proximal end portion to one lead distal end portion, and
three or more tissue sensing/stimulation electrodes disposed along the lead body,
the lead proximal end portion is sized and shaped to couple to the cardiac sensor/stimulator, the coupling electrically connecting each of the tissue sensing/stimulation electrodes to a signal processing circuit of the cardiac sensor/stimulator;
the signal processing circuit is adapted to sense in a first instance and stimulate in a second instance, the sensing or stimulation occurring by way of one or more selected tissue electrode configurations.
7. The system as recited in claim 6, wherein the signal processing circuit is adapted to select the tissue electrode configurations from the tissue sensing/stimulation electrodes of each lead and one or more indifferent return electrode associated with the cardiac sensor/stimulator.
8. The system as recited in claim 6, wherein the signal processing circuit is adapted to select the tissue electrode configurations using, at least in part, one or a combination of a stimulation threshold parameter, a stimulation impedance parameter, a stimulation selection parameter, a sense voltage parameter, a sense noise parameter, a tissue electrode location parameter, a heart chamber configuration parameter, a blood flow parameter, a posture parameter, a blood volume parameter, an acceleration or motion parameter, a spatial distance parameter, a time parameter, an impedance parameter, a blood oxygen parameter, or a stimulation energy parameter.
9. The system as recited in claim 6, further comprising an external programmer including a telemetry device communicatively couplable to the signal processing circuit of the cardiac sensor/stimulator,
the external programmer adapted to receive a selection of the tissue electrode configurations and communicate the selection to the signal processing circuit.
10. The system as recited in claim 6, wherein the cardiac sensor/stimulator includes at least one multi-pole connector cavity incorporated,
each multi-pole connector cavity is sized and shaped to receive and electrically engage with each lead proximal end portion.
11. The system as recited in claim 6, wherein the selected tissue electrode configurations include at least one tissue sensing/stimulation electrode positioned to sense or stimulate one or both of a left side of the heart or a right side of the heart.
12. The system as recited in claim 6, wherein the selected tissue electrode configurations include at least one tissue sensing/stimulation electrode positioned to sense or stimulate a left side of the heart, and
at least one tissue sensing/stimulation electrode positioned to sense or stimulate a right side of the heart.
13. The system as recited in claim 6, further comprising one or a combination of a posture sensor, a blood flow sensor, a blood pressure sensor, an impedance sensor, a blood volume sensor, an acceleration or motion sensor, a spatial distance sensor, or a blood oxygen sensor.
14. A method of using a system, the method comprising:
disposing portions of at least one lead within, on, or about a heart of a subject, one or more lead including a lead body extending from one lead proximal end portion to one lead distal end portion, and having three or more tissue sensing/stimulation electrodes disposed therealong;
evaluating a plurality of tissue electrode configurations for each configuration's ability to sense or stimulate the heart, the plurality of electrode configurations include combinations of, at least in part, the tissue sensing/stimulation electrodes of each lead; and
selecting one or more tissue electrode configurations for sensing or stimulating the heart.
15. The method as recited in claim 14, wherein disposing portions of the at least one lead includes disposing portions of a first lead within, on, or about a left side of the heart, and
disposing portions of a second lead within, on, or about a right side of the heart.
16. The method as recited in claim 14, wherein evaluating the plurality of tissue electrode configurations includes, at least in part, determining one or a combination of a stimulation threshold parameter, a stimulation impedance parameter, a stimulation selection parameter, a sense voltage parameter, a sense noise parameter, a tissue electrode location parameter, a heart chamber configuration parameter, a blood flow parameter, a posture parameter, a blood volume parameter, an acceleration or motion parameter, a spatial distance parameter, a time parameter, an impedance parameter, a blood oxygen parameter, or a stimulation energy parameter.
17. The method as recited in claim 14, wherein selecting the one or more tissue electrode configurations includes using the evaluation of the plurality of tissue electrode configurations.
18. The method as recited in claim 14, wherein selecting the one or more tissue electrode configurations includes using a signal processing circuit of the cardiac sensor/stimulator.
19. The method as recited in claim 14, wherein selecting the one or more tissue electrode configurations includes using a manual selection from a user.
20. The method as recited in claim 14, further comprising sensing the heart through the selected tissue electrode configurations, sensing the heart includes obtaining a sense indication signal.
21. The method as recited in claim 14, further comprising stimulating the heart through the selected electrode configurations, stimulating the heart includes using a sense indication signal.
22. The method as recited in claim 21, wherein stimulating the heart includes sequentially stimulating one or more chambers of the heart.
23. The method as recited in claim 21, wherein stimulating the heart includes multi-chamber stimulation of the heart.
24. The method as recited in claim 14, further comprising sensing or stimulating the heart through the selected tissue electrode configurations, sensing or stimulating includes electrically coupling at least two tissue sensing/stimulation electrodes.
25. The method as recited in claim 14, further comprising re-selecting the one or more tissue electrode configurations for sensing or stimulating the heart.
26. The method as recited in claim 14, further comprising coupling the lead proximal end with the cardiac sensor/stimulator.
27. A method of manufacturing a cardiac sensor/stimulator, the method comprising:
placing a signal processing circuit within a housing of the cardiac sensor/stimulator, the signal processing circuit is adapted to sense or stimulate a heart of a subject by way of one or more tissue electrode configurations selected using, at least in part, one or a combination of a stimulation threshold parameter, a stimulation impedance parameter, a stimulation selection parameter, a sense voltage parameter, a sense noise parameter, a tissue electrode location parameter, a heart chamber configuration parameter, a blood flow parameter, a posture parameter, a blood volume parameter, an acceleration or motion parameter, a spatial distance parameter, a time parameter, an impedance parameter, a blood oxygen level parameter, or a stimulation energy parameter;
forming a header including at least one multi-pole connector cavity disposed therein, each multi-pole connector is sized and shaped to receive a lead proximal end portion a lead; and
coupling the header to the housing.
28. The method as recited in claim 27, further comprising programming the signal processing circuit to select or accept manually entered selections for the tissue electrode configurations,
the tissue electrode configurations selected, at least in part, from any combination of three or more tissue sensing/stimulation electrodes of each lead coupled to the cardiac sensor/stimulator.
29. The method as recited in claim 27, further comprising programming the signal processing circuit to select or accept manually entered selections for the tissue electrode configurations,
the tissue electrode configurations selected, at least in part, from an electrical coupling of two or more tissue sensing/stimulation electrodes of at least one lead coupled to the cardiac sensor/stimulator.
30. The method as recited in claim 27, further comprising placing a communication circuit within the housing of the cardiac sensor/stimulator, the communication circuit is adapted to receive one or more inputs from an external programmer.
US11230989 2005-09-20 2005-09-20 Multi-site lead/system using a multi-pole connection and methods therefor Active 2028-06-27 US8731659B2 (en)
US11230989 US8731659B2 (en) 2005-09-20 2005-09-20 Multi-site lead/system using a multi-pole connection and methods therefor
EP20060803801 EP1937361B1 (en) 2005-09-20 2006-09-18 Multi-site lead/system
US20070066998A1 true true US20070066998A1 (en) 2007-03-22
US8731659B2 US8731659B2 (en) 2014-05-20
US11230989 Active 2028-06-27 US8731659B2 (en) 2005-09-20 2005-09-20 Multi-site lead/system using a multi-pole connection and methods therefor
US8731659B2 (en) 2014-05-20 grant
JP2009508594A (en) 2009-03-05 application
WO2007035662A1 (en) 2007-03-29 application
EP1937361B1 (en) 2016-10-26 grant
EP1937361A1 (en) 2008-07-02 application