Source: http://www.google.com/patents/US4497406?ie=ISO-8859-1
Timestamp: 2014-03-16 02:46:07
Document Index: 490798785

Matched Legal Cases: ['art. 4', 'art 2', 'art 2', 'art 2', 'art 2', 'art 2', 'art 2', 'art 2', 'art 2']

Patent US4497406 - Package for storage of medical container - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsA package for storing therein a medical container in conjunction with a deoxidizer covered on at least one side thereof with a gas-impervious sheet and on at least one other side thereof with a gas-pervious sheet, which package is characterized by comprising a tightly sealed container adapted to hold...http://www.google.com/patents/US4497406?utm_source=gb-gplus-sharePatent US4497406 - Package for storage of medical containerAdvanced Patent SearchPublication numberUS4497406 APublication typeGrantApplication numberUS 06/426,215Publication dateFeb 5, 1985Filing dateSep 28, 1982Priority dateMay 6, 1982Fee statusPaidAlso published asDE3279303D1, DE8231028U1, EP0093796A2, EP0093796A3, EP0093796B1Publication number06426215, 426215, US 4497406 A, US 4497406A, US-A-4497406, US4497406 A, US4497406AInventorsNobuyasu TakanashiOriginal AssigneeTerumo CorporationExport CitationBiBTeX, EndNote, RefManPatent Citations (17), Referenced by (16), Classifications (19), Legal Events (4) External Links: USPTO, USPTO Assignment, EspacenetPackage for storage of medical containerUS 4497406 AAbstract A package for storing therein a medical container in conjunction with a deoxidizer covered on at least one side thereof with a gas-impervious sheet and on at least one other side thereof with a gas-pervious sheet, which package is characterized by comprising a tightly sealed container adapted to hold the aforementioned deoxidizer in such a manner that the gas-pervious sheet sides of the deoxidizer rests on at least one of the inner sides thereof and provided in the inner side thereof adjoining the gas-pervious sheet side of the aforementioned deoxidizer with at least one passage for gas communicating with the atmosphere enclosed with the package.
What is claimed is: 1. A package for storing a medical container which contains a medical fluid, the package comprising:a tightly sealed substantially gas-impervious vessel having a recess formed on the bottom of said vessel, said recess opening to the inside of said vessel; said vessel having a gas barrier property sufficient to limit the oxygen concentration in the package to no more than 0.1% by volume when said tray has been heat sealed for 72 hours; a deoxidizer in said recess; a gas-pervious sheet covering one side of said deoxidizer and being between said deoxidizer and said bottom of said vessel; a gas-impervious sheet on at least one other side of said deoxidizer and facing upward and away from the bottom of said vessel; said medical container being in said vessel and above and in contact with said gas-impervious sheet; at least one passage provided on the bottom inner side of said vessel and adjoining said gas-pervious sheet side of said deoxidizer for communicating said gas-pervious sheet side of said deoxidizer with the atmosphere enclosed within said tightly sealed vessel of the package whereby said medical container is in gas communication with said deoxidizer; and wherein said at least one passage comprises grooves formed in a surface of said bottom of said vessel, and said grooves extending from under the gas-pervious sheet covering said one side of said deoxidizer to remote from said gas-pervious sheet covering said one side of said deoxidizer. 2. The package of claim 1, wherein said vessel comprises:a tray part having an upper opening, said recess being formed on the bottom of said tray part, and a flange portion provided around said opening; a lid member in the shape of a sheet; and a hotmelt adhesive layer adapted to be inserted between said flange portion and said lid member, said flange portion and said lid member being peel openably heat sealed to each other via said hotmelt adhesive layer. 3. The package of claim 2, wherein:said tray part comprises a laminated structure including a first polyolefin layer, an intermediate layer capable of barriering passage of gases and steam, and a second polyolefin layer, laminated on one another; said lid member is a laminated sheet member comprising a polyamide layer, a layer capable of barriering passage of gases and steam, and a layer having sufficient thermal resistance to withstand heat sealing, laminated on one another; and said hotmelt layer comprises a plurality of materials of dissimilar melting points and including at least one material identical with the polyolefin used in said tray part. 4. The package of claim 3, wherein at least one of said polyolefin layers of said tray part is formed of polypropylene and said hotmelt adhesive layer is formed of a blend of polyethylene with polypropylene.
12. The package of claim 3 wherein said intermediate layer is pervious to humidity in an amount of no more than 1 g/m.sup.2 per 24 hours measured at a temperature or 40
13. The package of claim 12, wherein said intermediate layer is pervious to humidity in an amount of no more than between 0.1-0.2 g/m.sup.2 per 24 hours measured at a temperature of 40 of 90%.
PREFERRED EMBODIMENT OF THE INVENTION Now, one preferred embodiment of this invention will be described below with reference to the accompanying drawing. The package for the storage of a medical container according to this invention causes a tray part 2 provided round the opening thereof with a flange portion 1 to form a recessed portion 3 for receiving a deoxidizer 7 in at least one side thereof, for example, the bottom side, and further to form at least one groove 4 in the bottom portion of the recess portion as illustrated in FIGS. 1-3. The term "groove" used in the specification may be a shape capable of forming a passage for gas and the shape is not limited. Within this deoxidizer receiving portion 3, the deoxidizer 7 covered on at least one side thereof with a gas-impervious sheet 5 such as aluminum foil, synthetic resin film, paper or cloth impregnated or coated with was or synthetic resin and on at least one other side thereof, generally the side opposite the aforementioned side, with a gas-pervious sheet 6 such as paper or cloth is received in such a manner that the gas-pervious sheet 6 is positioned on the groove 4 side. The aforementioned groove 4 is formed so as to reach the outside of the deoxidizer receiving portion 3 and form a free passage for gases. After the deoxidizer 7 and the medical container 8 have been set in position within the tray part 2, the lid member 10 is heat sealed through the medium of the hotmelt adhesive layer 9 to the tray part 2 peel openably.
The hotmelt adhesive layer constituting the inner layer 14 of the lid member 10 is desired to be formed of a blend of polyethylene with polypropylene. The weight ratio of the polyethylene to the polypropylene in the blend, when the outer layer 11 of the tray part 2 is made of polypropylene, is desired to fall in the range of 20:80 to 50:50 from the standpoint of both heat sealability and peel openability of the ray part. The thickness of the inner layer 14 is 30 to 60 μm, preferably 40 to 50 μm. This layer of the blend is superposed by a layer of polyamide, such as, for example, a layer of nylon 6 or nylon-6,6. This nylon layer permits the lid member to retain its strength. The intermediate layer 15 which is capable of barriering passage of gases and steam is desired to be formed of polyvinylidene chloride or ethylene-vinyl alcohol copolymer. Generally, polyvinylidene chloride is used as superposed on a polyolefin film, particularly a biaxially drawn polypropylene film. Generally, the molecular weight of the polyolefin is 5,000 to 1,000,000 preferably 100,000 to 500,000. The thickness of the polyolefin film is 20 to 40 μm. The molecular weight of the aforementioned polyvinylidene chloride is 8,000 to 20,000, preferably 10,000 to 15,000, and the thickness of the polyvinylidene chloride film is 5 to 10 μm. This film exhibits an outstanding ability to barrier passage of gases and steam. A still better barrier property is obtained by using a plurality of such layers capable of barriering passage of gases and steam in a superposed form. To ensure safe storage of a plastic medical container holding a medicinal fluid therein, the intermediate layer 15 is desired to have not more than 1 g/m.sup.2.24 hr (40 hr (40 prevention of growth of aerobic microorganisms, the gas barrier property of the intermediate layer 15 is desired to be not more than 0.1%/72 hr, preferably not more than 0.1%/50 hr of oxygen concentration within the package. Examples of the resin of the outer layer 16 which is possessed of thermal resistance enough to withstand the conditions of heat sealing include polyesters such as polyethylene terephthalate and polybutylene terephthalate, polyamides such as nylon 6 and nylon 6,6 and polypropylene. Among other polymers mentioned above, polyethylene terephthalate proves to be particularly desirable. The thickness of the outer layer 16 is 10 to 30 μm, preferably 12 to 25 μm.
EXAMPLES 1-7 As illustrated in FIGS. 1-4, in a tray part 2 formed of a laminated sheet comprising an outer layer 11 of polypropylene (having a molecular weight of 100,000 to 500,000) 500 μm in thickness, an intermediate layer 12 of ethylenevinyl alcohol copolymer (having a molecular weight of 10,000 to 50,000) 50 μm in thickness, and an inner layer 13 of polypropylene (having a molecular weight of 100,000 to 500,000) 500 μm in thickness, a pack of deoxidizer 7 held in a bag-like container having one wall thereof made of a gas-impervious sheet 5 obtained by vacuum depositing aluminum on a film of polyester (having a molecular weight of 100,000 to 500,000) and the other wall thereof made of a gas-pervious sheet 6 of paper was set in position in such a manner that the gas-pervious sheet 6 side thereof falls on the grooves 4 side. Further a blood bag 8 made of polyvinyl chloride and containing therein an anticoagulant was set in position in the tray part 2. Then, a lid member 10 obtained by laminating an inner nylon layer 15 μm in thickness, an intermediate layer 15 composed of two layers each of a film of biaxially drawn polypropylene (having a molecular weight of 100,000 to 500,000) 20 μm in thickness superposed by a layer of polyvinylidene chloride (having a molecular weight of 10,000 to 15,000) 10 μm in thickness, and an outer layer 16 of polyethylene terephthalate (having a molecular weight of 100,000 to 500,000) was heat sealed by high frequency to the flange portion 1 of the tray part 2 through the medium of a hotmelt adhesive layer 9 of a blend consisting of polyethylene (having a molecular weight of 50,000 to 100,000) and polypropylene (having a molecular weight of 100,000 to 500,000) in a weight ratio of 70:30 and superposed in advance on the nylon-6 (having a molecular weight of 20,000 to 50,000) layer of the flange portion 1 of the tray part 2. The packages thus produced were tested for concentration of oxygen contained therein by the use of a zirconia type analyzer (made by Toray Ltd). The results were as shown in Table 1. When the procedure described above was repeated by using ethylene-vinyl alcohol copolymer as the material for the layer of the lid member capable of berriering passage of gases and steam, there were obtained similar results.
COMPARATIVE EXPERIMENTS 1-5 The procedure of Example 1 was repeated, except that the tray part, though made of the same materials, had no grooves formed in the bottom side thereof and the bag-like container of the deoxidizer was set in position so that the gas-pervious sheet side thereof fell on the bottom side. The packages thus obtained were tested similarly to Example 1. The results were as shown in Table 1.
BRIEF DESCRIPTION OF THE DRAWING FIG. 1 is a perspective view illustrating one typical package of this invention for the storage of a medical container,
SUMMARY OF THE INVENTION The objects described above are attained by a package for storing therein a medical container in conjunction with a deoxidizer covered on at least one side thereof with a gasimpervious sheet and on at least one other side thereof with a gas-pervious sheet, which package is characterized by comprising a tightly sealed container adapted to hold the aforementioned deoxidizer in such a manner that the gas-pervious sheet sides of the deoxidizer rests on at least one of the inner sides thereof and provided in the inner side thereof adjoining the gas-pervious sheet side of the aforementioned deoxidizer with at least one recess communicating with the atmosphere enclosed with the package.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS3264165 *Nov 25, 1964Aug 2, 1966Gen Motors CorpInsulating meansUS3274004 *Apr 21, 1964Sep 20, 1966Curwood IncLaminated food packageUS3570748 *Jun 29, 1966Mar 16, 1971Standard Packaging CorpComposite film and methodUS3595465 *Sep 19, 1969Jul 27, 1971Bard Inc C RAutoclavable packageUS4055672 *Mar 31, 1976Oct 25, 1977Standard Packaging CorporationControlled atmosphere packageUS4239826 *Dec 28, 1978Dec 16, 1980American Can CompanyMulti-layer barrier filmUS4256784 *Aug 22, 1977Mar 17, 1981Hoechst AktiengesellschaftHeat-sealable plastic filmUS4355721 *Jul 30, 1980Oct 26, 1982American Can CompanyPackage for food productsUS4373636 *Feb 18, 1981Feb 15, 1983Hoffman Louis SContainerGB217968A * Title not availableGB813415A * Title not availableGB1091406A * Title not availableGB1215369A * Title not availableGB1248768A * Title not availableGB1527212A * Title not availableGB2003836A * Title not availableGB2024781A * Title not available* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS4667814 *Oct 22, 1985May 26, 1987Mitsubishi Gas Chemical Company, Inc.Oxygen absorbent packetUS4730726 *Apr 21, 1987Mar 15, 1988United States Surgical CorporationSealed sterile packageUS4857369 *Dec 14, 1987Aug 15, 1989Plm AbMethod for the closing of containersUS4922626 *Jan 29, 1988May 8, 1990Kolpak Manufacturing CompanyPizza delivery container and methodUS5011019 *Nov 20, 1989Apr 30, 1991Kabushiki Kaisha Hosokawa YokoContainer for packaging medicineUS5086915 *Jun 18, 1990Feb 11, 1992Terumo Kabushiki KaishaWrapping body for medical containerUS5217118 *Nov 29, 1991Jun 8, 1993Terumo Kabushiki KaishaPackaged articleUS5379895 *Feb 28, 1994Jan 10, 1995Minnesota Mining And Manufacturing CompanyPackage for surgical deviceUS5392590 *May 18, 1994Feb 28, 1995Kimberly-Clark CorporationPackaging and methods for reducing odors and strength loss caused by the irradiation of polyolefin-based productsUS5683795 *Apr 15, 1994Nov 4, 1997Kimberly-Clark Worldwide, Inc.Gamma irradiated aseptically tieable gownUS6019511 *Nov 22, 1993Feb 1, 2000Tredegar Industries, Inc.Protective assembliesUS6802708 *Jun 4, 2003Oct 12, 2004Matsushita Electric Industrial Co., Ltd.High frequency heating apparatusUS6976584 *Jun 26, 2002Dec 20, 2005Bausch & Lomb IncorporatedPackage for surgical implantUS7263814Jul 15, 2005Sep 4, 2007Oxyband Technologies, Inc.Method and apparatus for supplying gas to an areaUS7431498Mar 29, 2006Oct 7, 2008Jacquin Youngblood-JohnsonPortable supine patient support and cassette holderWO1987005278A1 *Sep 12, 1986Sep 11, 1987Coopervision IncSterile package with lifting strap* Cited by examinerClassifications U.S. Classification206/438, 206/524.2, 229/164.1, 428/475.8, 156/69, 206/524.6, 229/5.82, 206/557International ClassificationB65D81/18, A61J3/00, A61J1/16, A61J1/10, A61J1/14, B65D77/20, B65D81/20Cooperative ClassificationB65D81/18, A61J1/16, B65D2577/2025European ClassificationB65D81/18Legal EventsDateCodeEventDescriptionJul 22, 1996FPAYFee paymentYear of fee payment: 12Jul 22, 1992FPAYFee paymentYear of fee payment: 8Jul 26, 1988FPAYFee paymentYear of fee payment: 4Sep 28, 1982ASAssignmentOwner name: TERUMO KABUSHIKI KAISHA T/A TERUMO CORPORATION 44-Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:TAKANASHI, NOBUYASU;REEL/FRAME:004050/0606Effective date: 19820916RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google