Source: http://www.google.com/patents/US8172839?dq=6317900
Timestamp: 2014-07-14 10:40:06
Document Index: 457206740

Matched Legal Cases: ['art 2', 'art 61', 'art 62', 'art 70', 'art 2', 'art 2', 'art 62', 'art 2', 'application No. 07']

Patent US8172839 - PFO closing device - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign in<nobr>Advanced Patent Search</nobr>PatentsA PFO closing device for bringing the septum primum and the septum secundum into contact with each other and joining them together includes a clamping mechanism and energy supplying device. The clamping mechanism includes a needle part for puncturing the septum primum, and a clamping member for cooperating...http://www.google.com/patents/US8172839?utm_source=gb-gplus-sharePatent US8172839 - PFO closing deviceAdvanced Patent SearchPublication numberUS8172839 B2Publication typeGrantApplication numberUS 12/230,090Publication dateMay 8, 2012Filing dateAug 22, 2008Priority dateFeb 24, 2006Also published asCN101389282A, CN101389282B, CN102018570A, CN102018570B, CN102028539A, CN102028539B, CN102028540A, CN102028540B, EP1986559A1, EP1986559B1, EP2322112A2, EP2322112A3, EP2368509A2, EP2368509A3, EP2368510A2, EP2368510A3, US8574265, US8603139, US20090005780, US20120215255, US20120215256, US20130116684, WO2007100067A1Publication number12230090, 230090, US 8172839 B2, US 8172839B2, US-B2-8172839, US8172839 B2, US8172839B2InventorsYukitoshi KatoOriginal AssigneeTerumo Kabushiki KaishaExport CitationBiBTeX, EndNote, RefManPatent Citations (92), Non-Patent Citations (1), Referenced by (4), Classifications (10), Legal Events (1) External Links: USPTO, USPTO Assignment, EspacenetPFO closing deviceUS 8172839 B2Abstract A PFO closing device for bringing the septum primum and the septum secundum into contact with each other and joining them together includes a clamping mechanism and energy supplying device. The clamping mechanism includes a needle part for puncturing the septum primum, and a clamping member for cooperating with the needle part in clamping therebetween tissue of the septum primum and the septum secundum. The energy supplying device supplies energy for joining the tissues clamped by the needle part and the clamping member. The clamping mechanism is mounted in a catheter so as to be protrudable from and retractable into the catheter.
TECHNOLOGICAL FIELD The present invention generally relates to a medical device. More specifically, the invention pertains to a patent foramen ovale (PFO) closing device for closing a PFO in a person's heart.
SUMMARY A patent foramen oval (PFO) closing device for bringing the septum primum and the septum secundum into contact with each other and joining them together comprises a catheter dimensioned to be positioned in a living body and advanced into an atrium of a heart, a needle part slidably positioned inside the catheter for puncturing the septum primum, a clamping member mounted on the catheter and cooperable with the needle part to clamp, between the clamping member and the needle part, tissue of the septum primum and the septum secundum, and an energy supplying means operatively connected to at least one of the needle part and the clamping member for supplying energy to join the tissue clamped between the needle part and the clamping member. The PFO closing device posses a relatively simple configuration, yet allows the SP and the SS to be reliably joined to each other through a relatively easy procedure, without leaving any foreign matter indwelling in the patient's body.
The positioning and holding means has a main tube passing through the catheter and capable of being operated externally, an operating member provided in the main tube so as to be movable axially forwards and rearwards is protruded from the distal end of the main tube, an intermediate sleeve body and a tip sleeve body are provided coaxially with the operating member, and a contact member brought into contact with the tip sleeve body by pulling the operating member is provided at a distal end portion of the operating member; the main tube and the intermediate sleeve body�are connected to each other by a first elastic wire member, the intermediate sleeve body and the tip sleeve body are connected to each other by a second elastic wire member and a third elastic wire member projectingly deformable more easily than the second elastic wire member; the first elastic wire member is curved outwards by pulling the operating member to thereby function as the positioning part making springy contact with the inner edge of the foramen ovale, and by further pulling the operating member, the second elastic wire member is curved so that the tip sleeve body and the contact member function as a holding part for holding the septum primum, and the third elastic wire member is curved outwards to thereby function as a crease smoothing part for smoothing out creases present in the septum primum. This also ensures not only the safety, facility, accurateness, and speediness of the procedure but also a simpler configuration of the PFO closing device.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a schematic cross-sectional view showing the use of a first embodiment of the PFO closing device disclosed herein.
DETAILED DESCRIPTION A first embodiment of the PFO closing device disclosed here is described with reference to FIGS. 1-3. As shown in FIG. 1, the PFO closing device according to this embodiment generally includes clamping means 1 for clamping a septum primum (hereinafter referred to as SP M2) and a septum secundum (hereinafter referred to as SS M1), and energy-supplying means 20 for supplying energy to join the tissues clamped by the clamping means 1. The clamping means 1 is movably positioned in the distal end (tip) of an elongated member 30, which includes a lumen, in a manner allowing the clamping means 1 to protrude out of and retract into (e.g., be movable forward and rearward) the elongated member. In the illustrated embodiment, the elongated hollow member (elongated lumen-possessing member) is a percutaneous catheter 30. In use, the clamping means 1, while being wholly stored or positioned in the catheter 30, is inserted in an inferior vena cava J. Then, in performing the procedure, the clamping means 1 protrudes from the distal end of the catheter 30, and the tissues of the SS M1 and the SP M2 of a heart in which a defect 0 (FIG. 4) of Patent Foramen Ovale (hereinafter referred to also as PFO 0) exists are clamped. In this condition, the tissues are joined by the energy supplied to the clamping means 1, whereby the defect 0 is closed.
The operating member 7, which can be composed of a comparatively stiff wire member, need not necessarily be connected to the needle part 2 side, and may instead be connected to the clamping member 3. The operating member 7 may be of any desired construction allowing it to move the clamping means 1 forwards and rearwards inside the catheter 30. By way of example, a wire of stainless steel, an Ni�Ti alloy, titanium, or the like can be used as the operating member 7.
Preferred specific examples of the elastic wire members 41, 42 are metal wires of stainless steel, nickel-titanium alloy, superelastic alloy (e.g., Ni�Ti alloy), or the like, with outside diameter of about 0.1 to 0.5 mm. Incidentally, the elastic wire members 41, 42 comprising the positioning means 40 are not limited to a pair of wire members, and may be provided in a greater number.
The material forming the clamping member 3B, is preferably a SUS material with an outside diameter of 0.1 to 2 mm. However, other materials which do not exert bad influences on the living bodies may also be used, for example gold, silver, platinum, tungsten, palladium, or alloys thereof, Ni�Ti alloy, titanium alloys, etc. With respect to the operating member 7 and the positioning means 40, wire members formed of such material as SUS, gold, silver, platinum, tungsten, palladium, alloys thereof, Ni�Ti alloy, titanium alloys, etc. and having an outside diameter of 0.1 to 0.5 mm can be used.
The catheter 30 in this embodiment is one in which the lumens are a part of the catheter 30 rather than a support, and the configuration is such that the catheter 30 can be thought of as being obtained by elongating the above-mentioned support 50. The catheter 30 is provided therein with five lumens. The operating member 7 is movably positioned in an elastic main tube 63 in a manner permitting forward and rearward movement of the operating member 7. The elastic main tube 63 and the operating member 7 pass through a centrally located lumen L5 so that the positioning part 61 and the holding part 62 are operated by a hand-operated operating part 70 connected to the proximal end side of the operating member 7. In the following description, the hand-operated operating part side of the PFO closing device is referred to as �the proximal side�, and the side of the needle part 2 or the SP M2 is referred to as �the distal side�.
Preferable specific examples of the first and second elastic wire members 66, 67 are metal wires formed of stainless steel, nickel-titanium alloy, superelastic alloy (e.g., Ni�Ti alloy) or the like, with an outer diameter of about 0.1 to 0.5 mm. In addition, the metal wire may be covered with a resin (flexible) tube, for preventing the elastic wire members 66, 67 from damaging the tissues.
After the position of the distal end of the operating member 7 is confirmed, the grip 78 is retracted until the contact member 68 of the operating member 7 abuts on the tip sleeve body 65, as shown in FIG. 28B (the retraction amount is �δ1� in FIG. 28B). Then, the first operating body 73 is operated to locate the second elastic wire members 67, the needle part 2, and the clamping member 3B in the vicinity of the SP M2, and the whole body of the holding part 62 is inserted into the left atrium L of the heart.
With the grip 78 retracted further (the retraction amount is �δ2� in FIG. 28C), the operating force of the retraction is transmitted by the operating member 7 and through the contact member 68, the tip sleeve body 65, the second elastic wire members 67, and the intermediate sleeve body 64 to the first elastic wire members 66 which are firmly attached to the distal end of the main tube 63. The first elastic wire members 66 are deformed so as to project in arcuate shapes radially outwardly, as shown in FIG. 28C. It should be noted here, however, the second elastic wire members 67 are not yet deformed in this instance.
With the operating member 7 retracted, the operating force is transmitted through the contact member 68, the tip sleeve body 65, the second elastic wire members 67, and the intermediate sleeve body 64 to the first elastic wire members 66 firmly attached to the distal end of a main tube 63, whereby the first elastic wire members 66 are deformed so that they project radially outwards into arcuate shapes. Where the projecting deformation of the first elastic wire members 66 is performed in the vicinity of the PFO 0, the needle part 2 can be centered in relation to the PFO 0. It should be noted here, however, that the second elastic wire members 67 and the third elastic wire members 92�are not yet deformed at this time.
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examinerNon-Patent CitationsReference1European Office Action in corresponding application No. 07 715 127.2-1265 dated Feb. 6, 2009.Referenced byCiting PatentFiling datePublication dateApplicantTitleUS8460287 *Aug 28, 2008Jun 11, 2013Terumo Kabushiki KaishaPFO closing deviceUS8597294 *Aug 28, 2008Dec 3, 2013Terumo Kabushiki KaishaBiological tissue closing deviceUS20090069809 *Aug 28, 2008Mar 12, 2009Terumo Kabushiki KaishaPfo closing deviceUS20090069810 *Aug 28, 2008Mar 12, 2009Terumo Kabushiki KaishaBiological tissue closing device* Cited by examinerClassifications U.S. Classification606/50, 606/215International ClassificationA61B18/18Cooperative ClassificationA61B2017/00243, A61B18/1445, A61B18/1492, A61B2017/00575, A61B2018/1432, A61B2017/2945European ClassificationA61B18/14VLegal EventsDateCodeEventDescriptionAug 22, 2008ASAssignmentOwner name: TERUMO KABUSHIKI KAISHA, JAPANFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:KATO, YUKITOSHI;REEL/FRAME:021484/0859Effective 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