Source: http://www.google.com/patents/US20030199936?dq=6,242,741
Timestamp: 2015-11-25 19:14:44
Document Index: 490179765

Matched Legal Cases: ['art. 5', 'art. 6', 'art. 8', 'art. 9', 'art. 15', 'art. 16', 'art. 21']

Patent US20030199936 - Atrioventricular delay adjustment - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsIn a system that includes a ventricular pacemaker, the system adjusts an atrioventricular delay to synchronize the onset of isovolumetric contraction with the completion of ventricular filling. The system adjusts the atrioventricular delay as a function of electrical and pressure data from the heart....http://www.google.com/patents/US20030199936?utm_source=gb-gplus-sharePatent US20030199936 - Atrioventricular delay adjustmentAdvanced Patent SearchPublication numberUS20030199936 A1Publication typeApplicationApplication numberUS 10/127,038Publication dateOct 23, 2003Filing dateApr 22, 2002Priority dateApr 22, 2002Also published asCN1662278A, CN100478043C, DE60324911D1, EP1499386A1, EP1499386B1, US6882882, WO2003089057A1Publication number10127038, 127038, US 2003/0199936 A1, US 2003/199936 A1, US 20030199936 A1, US 20030199936A1, US 2003199936 A1, US 2003199936A1, US-A1-20030199936, US-A1-2003199936, US2003/0199936A1, US2003/199936A1, US20030199936 A1, US20030199936A1, US2003199936 A1, US2003199936A1InventorsChester Struble, Lambert MuhlenbergOriginal AssigneeStruble Chester L., Lambert MuhlenbergExport CitationBiBTeX, EndNote, RefManPatent Citations (50), Referenced by (23), Classifications (9), Legal Events (3) External Links: USPTO, USPTO Assignment, EspacenetAtrioventricular delay adjustment
1. An implantable medical device system comprising: a pacemaker that paces a ventricle of a heart at an atrioventricular delay following an atrial event; a pressure monitor that monitors the onset of isovolumetric contraction of the heart; and a processor that: selects a first interval representing a time between a first cardiac occurrence and an atrioventricular valve closure, wherein the cardiac occurrence is one of an atrial sense, an atrial pace and a ventricular pace; measures a second interval as a function of a time between a second cardiac occurrence and an onset of isovolumetric contraction; computes a difference between the first interval and the second interval; and adjusts the atrioventricular delay as a function of the computed difference. 2. The system of claim 1, wherein the processor selects the first interval as a function of a measured heart rate. 3. The system of claim 1, wherein the first interval represents a time between a ventricular pace and a mitral valve closure. 4. The system of claim 1, wherein measuring the second interval comprises measuring a pressure in a left ventricle of the heart. 5. The system of claim 1, wherein measuring the second interval comprises detecting a zero crossing in the derivative of the pressure in a left ventricle of the heart. 6. The system of claim 1, further comprising a pressure sensor disposed in the left ventricle of the heart, the pressure sensor coupled to the pressure monitor. 7. The system of claim 6, further comprising a lead having a proximal end and a distal end, wherein the pressure sensor is disposed on the distal end of the lead, and wherein the distal lead penetrates an interventricular septum of the heart. 8. The system of claim 1, further comprising an atrial electrode coupled to the pacemaker, the atrial electrode disposed in an atrium of the heart. 9. The system of claim 1, wherein the atrial event is a sensed atrial activation. 10. The system of claim 1, wherein the atrial event is an atrial pacing pulse. 11. The system of claim 1, further comprising memory that stores a lookup table of values of the first interval as a function of heart rate, and wherein the processor selects a value of the first interval from the lookup table as a function of a measured heart rate. 12. The system of claim 1, further comprising memory that stores a formula that defines the first interval as a function of heart rate, and wherein the processor computes a value of the first interval by applying the formula to a measured heart rate. 13. The system of claim 1, wherein the pacemaker, the pressure monitor and the processor are included in a single implantable device. 14. The system of claim 1, further comprising a ventricular electrode coupled to the pacemaker, the ventricular electrode disposed proximate to a ventricle of the heart. 15. The system of claim 14, wherein the ventricular electrode is disposed in a right ventricle of the heart. 16. The system of claim 1, wherein the processor computes the computed difference by taking the difference between the first interval and the second interval. 17. A method comprising: selecting a first interval representing a time between a first cardiac occurrence and an atrioventricular valve closure, wherein the cardiac occurrence is one of an atrial sense, an atrial pace and a ventricular pace; measuring a second interval as a function of a time between a second cardiac occurrence and an onset of isovolumetric contraction; computing a difference between the first interval and the second interval; and adjusting the atrioventricular delay as a function of the computed difference. 18. The method of claim 17, further comprising measuring a heart rate, wherein selecting the value of the first interval comprises selecting the value of the first interval as a function of the measured heart rate. 19. The method of claim 17, wherein the first interval represents a time between a ventricular pace and a mitral valve closure. 20. The method of claim 17, wherein measuring the second interval comprises measuring a pressure in a left ventricle of the heart. 21. The method of claim 17, wherein measuring the second interval comprises detecting a zero crossing in