Source: https://patents.google.com/patent/US9999749B2/en
Timestamp: 2018-12-18 10:55:35
Document Index: 716847767

Matched Legal Cases: ['Application No. 2013', 'Application No. 13173132', 'Application No. 2013', 'Application No. 2013', 'Application No. 2013', 'Application No. 14152295', 'Application No. 2012', 'Application No. 201410010309']

US9999749B2 - Catheter - Google Patents
US9999749B2
US9999749B2 US15358262 US201615358262A US9999749B2 US 9999749 B2 US9999749 B2 US 9999749B2 US 15358262 US15358262 US 15358262 US 201615358262 A US201615358262 A US 201615358262A US 9999749 B2 US9999749 B2 US 9999749B2
US15358262
US20170072166A1 (en )
Tadanori HIROSHIGE
Makoto NISHIGISHI
Kenji Kaneda
Tatsuhiko KAJII
A61M25/0012—Making of catheters or other medical or surgical tubes with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
A61M25/0051—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids made from fenestrated or weakened tubing layer
A61M25/0052—Localized reinforcement, e.g. where only a specific part of the catheter is reinforced, for rapid exchange guidewire port
A61M25/0053—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids having a variable stiffness along the longitudinal axis, e.g. by varying the pitch of the coil or braid
A catheter includes an inner layer, and a braid provided on an outer periphery of the inner layer. The braid includes a first wire and a second wire that are woven together. The catheter further includes a tip provided on a distal end of the inner layer and a distal end of the braid. A residual portion having a sharp shape formed at a distal end of the first wire when the first wire is cut is not left untreated, but is formed into a bulging portion.
This application is a continuation application of U.S. application Ser. No. 14/100,943, filed Dec. 9, 2013, which claims priority to Japanese Patent Application No. 2013-015013 filed in the Japan Patent Office on Jan. 30, 2013, the entire contents of which are incorporated herein by reference.
The disclosed embodiments relate to a medical device. Specifically, the disclosed embodiments relate to catheters to be inserted into a blood vessel, an alimentary canal, a ureter, etc., and more particularly, to a tip of a braid that serves as a reinforcing member of the catheter.
Catheters to be inserted into a blood vessel, an alimentary canal, a ureter, etc., include an inner layer made of a resin, an outer layer that covers the outer periphery of the inner layer and that is made of a resin, and a braid interposed between the inner layer and the outer layer and serves as a reinforcing member. To achieve the performances (pushing performance, torque transmission performance, pressure resistance, etc.) required of the catheters, the braid is generally formed by weaving wires made of a metal, such as tungsten or stainless steel.
The wires included in the braid tend to spread apart at the distal end of the braid owing to the tension of the wires. To prevent this, a braid including a weld portion that extends in the circumferential direction and in which the wires are welded together at the distal end of the braid has been proposed (see, for example, International Publication No. 2008/019236). According to this publication, the weld portion is formed in a region where the wires cross each other, and then excess portions of the wires in a region on the distal side of the weld portion are removed. Thus, the braid including the weld portion that extends in the circumferential direction at the distal end thereof is formed.
However, according to the above-described method, since the excess portions of the wires are cut off in the weld portion, the area in which the wires are welded together is reduced to half the initial area. Therefore, there is a limit to the welding strength. In particular, with the reduction in size of the catheters, the thickness of the braid tends to be reduced, and reduction in the thickness of the wires leads to a reduction in the welding strength. As a result, there is a risk that the wires included in the braid will spread apart.
In the above-described method, if the wires are cut precisely along the center of the weld portion that extends in the circumferential direction, the wires can be cut without leaving sharp portions at the distal end of the braid. However, in practice, intervals between the wires in the woven state (in other words, intervals between the adjacent wires) are often not uniform owing to variation in the wire pitch that occurs in the weaving process, and it is difficult to cut the wires precisely along the center of the weld portion. When the excess portions of the wires are cut at a position shifted from the center of the weld portion, the wires include sharp portions at the distal end of the braid. Therefore, when a doctor strongly pushes the catheter that has been inserted into a blood vessel, an alimentary canal, a ureter, etc., there is a risk that the distal end of the braid will penetrate the tip. This problem becomes more serious when the catheter is required to be small to reduce the patient's pain and the thickness and length of the tip are reduced accordingly.
The disclosed embodiments have been made in light of the above-described circumstances, and an object of the disclosed embodiments is to provide a catheter in which a sufficient welding strength is ensured between wires of a braid even when the thickness of the wires and the thickness of a tip are reduced, and with which the occurrence of penetration of the braid through the tip can be reduced.
The above-described object can be achieved by the following means.
According to some aspects of the invention, a catheter includes an inner layer; a braid provided on an outer periphery of the inner layer and including a first wire and a second wire, which are woven together, and a bulging portion provided on at least one of a distal end of the first wire and a distal end of the second wire; and a tip provided on a distal end of the inner layer and a distal end of the braid, the tip covering the bulging portion.
In catheters according to the above aspects, at least one of the first wire and the second wire has the bulging portion at the distal end thereof. Thus, the at least one of the first wire and the second wire that has been cut such that a sharp portion is formed is not left untreated, and the risk that the braid will penetrate the tip can be reduced. In addition, since the bulging portion provided at the distal end of the braid functions as an anchor on the tip, the risk that the tip will be pulled off from the catheter shaft can also be reduced.
FIG. 1 illustrates the entire body of a catheter according to an embodiment.
FIG. 2 illustrates a distal portion of the catheter from which a tip and a part of an outer layer are removed for the purpose of explanation.
FIG. 3 is a sectional view of a distal portion of a catheter shaft and the tip.
FIG. 4A is a plan view of a braid in a state before a cutting process.
FIG. 4B is a plan view of the braid in a state after the cutting process.
FIG. 4C is a plan view of the braid having bulging portions formed at the distal end thereof.
FIG. 5A is a schematic diagram illustrating the distal ends of a first wire and a second wire after the cutting process.
FIG. 5B is a schematic diagram illustrating the state in which a bulging portion is formed at the distal end of the first wire.
FIG. 6A is a schematic diagram illustrating the distal ends of the first wire and the second wire after the cutting process.
FIG. 6B is a schematic diagram illustrating the state in which a first bulging portion is formed at the distal end of the first wire and a second bulging portion is formed at the distal end of the second wire.
FIG. 7 illustrates an embodiment other than the embodiment illustrated in FIG. 2.
FIGS. 8A to 8C illustrate an embodiment other than the embodiment illustrated in FIGS. 6A and 6B.
A catheter 1 according to an embodiment will be described with reference to FIGS. 1 to 8C. In FIGS. 1 to 3 and 7, a distal end of the catheter 1 that is inserted into a body is shown at the left side, and a proximal end of the catheter 1 that is manipulated by an operator, such as a doctor, is shown at the right side. In each figure, the sizes of components smaller than other components, such as first wires 26 a, second wires 26 b, bulging portions 27, 37, 47, and 57, etc., of a braid 26, which will be described below, are exaggerated to facilitate understanding.
The catheter 1 illustrated in FIG. 1 is a tubular medical device having an overall length of about 1200 mm. The catheter 1 mainly includes a flexible catheter shaft 10, a tip 12 bonded to the distal end of the catheter shaft 10, and a connector 14 bonded to the proximal end of the catheter shaft 10.
As illustrated in FIGS. 2 and 3, the catheter shaft 10 includes an inner layer 24, a braid 26 that serves as a reinforcing member, and an outer layer 28 in that order in the radial direction.
The inner layer 24 is made of a resin, and defines a lumen 18 which allows a guidewire or another catheter to be inserted therethrough. The resin material of the inner layer 24 is not particularly limited. In the present embodiment, polytetrafluoroethylene (PTFE) is used.
The braid 26, which serves as a reinforcing member, is formed on the outer periphery of the inner layer 24. As illustrated in FIGS. 2 and 4A to 4C, the braid 26 includes first wires 26 a and second wires 26 b that are woven in a mesh pattern. In the present embodiment, eight first wires 26 a and eight second wires 26 b, which are sixteen wires in total (8×8), are woven together. More specifically, the first wires 26 a are wound in one direction, and the second wires 26 b are wound in another direction.
The combination of the numbers of the first and second wires 26 a and 26 b of the braid 26 is not limited to 8×8, and may instead be, for example, 4×4 or 2×2 when the numbers are equal to each other, or 4×8 or 2×4 when the numbers are not equal to each other. The first and second wires 26 a and 26 b may have the same wire width. Alternatively, the wire width of the first wires 26 a may be greater than that of the second wires 26 b. The first and second wires 26 a and 26 b are woven such that each wire extends over two wires and under two wires alternately. However, the weave structure is not limited to this, and the first and second wires 26 a and 26 b may instead be woven such that each wire extends over one wire and under one wire alternately.
The first and second wires 26 a and 26 b may either be made of the same material or different materials. In the present embodiment, the first wires 26 a are made of a stainless steel (SUS316) and have a low melting point, and the second wires 26 b are made of tungsten and have a high melting point. However, the materials of the first and second wires 26 a and 26 b are not particularly limited. For example, materials other than metals (for example, reinforced plastics) may be used. In the present embodiment, the first wires 26 a have a rectangular cross section and the second wires 26 b have a circular cross section. However, the cross sectional shapes of the first and second wires 26 a and 26 b are not limited to this. The first and second wires 26 a and 26 b may both have a rectangular or circular cross section.
As illustrated in FIGS. 2 and 3, bulging portions 27 are provided at the distal ends of the first wires 26 a included in the braid 26. The shape of the bulging portions 27 is not particularly limited as long as the bulging portions 27 are not sharp (in other words, as long as the bulging portions 27 have a rounded shape, such as a spherical or elliptical shape).
The outer layer 28, which is made of a resin, is formed on the outer periphery of the braid 26 so as to cover the inner layer 24 and the braid 26. The resin material of the outer layer 28 is not particularly limited, and polyamide, polyamide elastomer, polyester, polyurethane, etc., may be used.
As illustrated in the sectional view of FIG. 3, the entirety of the catheter shaft 10 excluding the tip 12 is covered by the outer layer 28. The outer layer 28 is made of resin materials having different hardnesses so that the flexibility of the outer layer 28 increases toward the distal end from the proximal end of the catheter shaft 10. In FIG. 3, the braid 26 is covered with an intermediate layer 29 made of a resin and the outer layer 28 made of a resin. However, the structure of the braid 26 is not limited to this. The outer diameter of the catheter shaft 10 may be reduced by fanning the catheter shaft 10 without using the intermediate layer 29. The intermediate layer 29 may be made of a resin material that is either the same as or different from the material of the inner layer 24 or the outer layer 28.
In the sectional view of FIG. 3, the catheter shaft 10 is shaped so as to have a constant inner diameter in the axial direction. However, the shape of the catheter shaft 10 is not limited to this. The catheter shaft 10 may instead be tapered such that the diameter thereof increases toward the proximal end and is small only at the distal end.
The tip 12 made of a resin is attached to the distal end of the catheter shaft 10. The tip 12 is a cylindrical member having a distal opening 15. The resin material of the tip 12 is not particularly limited, and polyurethane, polyurethane elastomer, etc., may be used. The tip 12 may contain radiopaque powder. When, for example, the tip 12 contains radiopaque powder (for example, tungsten powder) in the range of about 65 w % to about 90 w %, a doctor, for example, can recognize the accurate position of the catheter 1 during coronary angiography.
The bulging portions 27 provided at the distal end of the braid 26 will now be described.
Referring to FIG. 4A, excess portions of the first and second wires 26 a and 26 b of the braid 26, in which the first and second wires 26 a and 26 b are woven together, are cut off by applying a laser beam to a cutting section 32 (in other words, to the first wires 26 a at the positions shown by the black circles and to the second wires 26 b at the position shown by black rectangles). To prevent the first and second wires 26 a and 26 b from spreading apart, the first and second wires 26 a and 26 b are welded together at intersections 30 thereof before the excess portions of the first and second wires 26 a and 26 b are cut. In FIG. 4A, the first and second wires 26 a and 26 b are welded together at all of the intersections 30 at the distal end of the braid 26. However, the locations at which the first and second wires 26 a and 26 b are welded together are not limited to this. When the welding strength between the first and second wires 26 a and 26 b is sufficient, the first and second wires 26 a and 26 b may be left unwelded at some of the intersections 30 located at the distal end of the braid 26.
Although the cutting section 32 is shifted from the intersections 30 in FIG. 4A, the position of the cutting section 32 is not limited to this. In the case where the intervals between the wires in the woven state (in other words, intervals between the adjacent wires) are not uniform owing to variation in the wire pitch, the cutting section 32 may extend through some of the intersections 30 instead of extending only through positions shifted from the intersections 30. However, to ensure sufficient welding strength between the first and second wires 26 a and 26 b, the cutting section 32 is preferably shifted from the intersections 30, as illustrated in FIG. 4A.
When the excess portions of the first and second wires 26 a and 26 b are cut off, the first and second wires 26 a and 26 b have sharp shapes at the cutting section 32, as illustrated in FIGS. 4B and 5A. In the present embodiment, each first wire 26 a has a residual portion 36 a having a sharp shape at the distal end thereof, and each second wire 26 b has a residual portion 36 b having a sharp shape at the distal end thereof.
Subsequently, the laser beam is applied to the residual portion 36 a having a sharp shape (at the position shown by the black circle in FIG. 5A). As a result, as illustrated in FIGS. 4C and 5B, bulging portions 27 are formed which have a rounded shape and which are thicker than the first wires 26 a. The bulging portions 27 may be made of a material that is either the same as or different from the material of the first wires 26 a. In the case where the bulging portions 27 are made of the same material as that of the first wires 26 a, the risk that the bulging portions 27 will be separated from the distal ends of the first wires 26 a can be reduced.
The laser beam used to cut the first and second wires 26 a and 26 b along the cutting section 32 and form the bulging portions 27 is not particularly limited. In the present embodiment, a YAG pulse laser beam is used.
As described above, the residual portions 36 a having a sharp shape that are formed at the distal ends of the first wires 26 a when the first wires 26 a are cut are not left untreated, but are formed into the bulging portions 27 having a rounded shape. Thus, the number of sharp portions of the wires at the distal end of the braid 26 can be reduced. As a result, even when a doctor strongly pushes the catheter I that has been inserted into a blood vessel, the risk that the braid 26 will penetrate the tip 12 can be reduced. In addition, since the bulging portions 27 formed at the distal ends of the first wires 26 a are thicker than the first wires 26 a, the bulging portions 27 function as anchors on the tip 12. Therefore, the risk that the tip 12 will be pulled off from the catheter shaft 10 can also be reduced. Since the position at which the excess portions of the first wires 26 a are cut (in other words, the position of the cutting section 32) is not particularly limited, the above-described structure is useful also when the intervals between the first wires 26 a in a woven state are not uniform owing to variation in the wire pitch.
According to the above description, the bulging portions 27 are formed only at the distal ends of the first wires 26 a. However, bulging portions are not limited to this. As illustrated in FIGS. 6A and 6B, the laser beam may be applied not only to the residual portion 36 a having a sharp shape at the distal end of each first wire 26 a (at the position shown by the black circle in FIG. 6A) but also to the residual portion 36 b having a sharp shape at the distal end of each second wire 26 b (at the position shown by the black rectangle in FIG. 6A), so that the bulging portion 27 is formed at the distal end of each first wire 26 a and a bulging portion 37 is formed at the distal end of each second wire 26 b.
When the bulging portions 27 made of the same material as the material of the first wires 26 a are formed at the distal ends of the first wires 26 a and the bulging portions 37 made of the same material as the material of the second wires 26 b are formed at the distal ends of the second wires 26 b, the risk that the braid 26 will penetrate the tip 12 can be further reduced. In addition, since the bulging portions 27 and 37 are made of the same materials as the materials of the first and second wires 26 a and 26 b, respectively, the risk that the bulging portions 27 and 37 will be separated from the distal ends of the first and second wires 26 a and 26 b can be reduced. In addition, since the anchoring effect can be provided by the bulging portions 27 and 37, the risk that the tip 12 will be pulled off from the catheter shaft 10 can be reduced.
An embodiment other than the embodiment illustrated in FIG. 2 will now be described. Instead of forming the bulging portions 27 and 37 at the distal ends of the first and second wires 26 a and 26 b, respectively, an annular bulging portion 47 may be formed so as to extend through the distal ends of the first and second wires 26 a and 26 b, as illustrated in FIG. 7. Since the bulging portion 47 is formed in an annular shape, the first and second wires 26 a and 26 b may be welded together in a region other than the intersections 30. Therefore, the welding strength between the first and second wires 26 a and 26 b can be further increased and the thickness of the braid 26 can be reduced.
Although the annular bulging portion 47 is formed so as to extend through the distal ends of both the first wires 26 a and the second wires 26 b in FIG. 7, the bulging portion 47 is not limited to this. For example, after the excess portions of the first wires 26 a are cut off, the bulging portion 47 may be formed so as to extend through the distal ends of the first wires 26 a by connecting the residual portions 36 a having a sharp shape at the distal ends of the first wires 26 a with the same material as the material of the first wires 26 a. In addition, the bulging portions 37 may be formed at the distal ends of the second wires 26 b, as illustrated in FIG. 6B. Thus, the annular bulging portion 47 may be formed so as to extend through the distal ends of either or both of the first and second wires 26 a and 26 b, thereby welding either or both of the first and second wires 26 a and 26 b together. As a result, the first and second wires 26 a and 26 b of the braid 26 can be prevented from spreading apart.
The material of the bulging portion 47 may be the same as the material of the first wires 26 a or the material of the second wires 26 b. Alternatively, the material of the bulging portion 47 may be different from the materials of the first and second wires 26 a and 26 b. For example, when a radiopaque material (for example, gold, platinum, tungsten, or an alloy thereof) is used, the bulging portion 47 functions also as a marker.
According to the above description, the bulging portions 27, 37, and 47 are provided on the distal ends of either or both of the first and second wires 26 a and 26 b. However, the bulging portions are not limited to this. As illustrated in FIGS. 8A to 8C, a bulging portion 57 may be formed at the intersection 30 of the first and second wires 26 a and 26 b. In this example, a laser beam is applied to the residual portion 36 a having a sharp shape at the distal end of the first wire 26 a (at the position shown by the black circle in FIG. 8A) and the residual portion 36 b having a sharp shape at the distal end of the second wire 26 b (at the position shown by the black rectangle in FIG. 8A). The conditions, such as the intensity and the position, of the laser beam are adjusted so that the bulging portion 37 is formed at the distal end of the second wire 26 b and the bulging portion 57 is formed at the intersection 30. The bulging portion 57 is formed by melting the residual portion 36 a having a sharp shape with the energy of the laser beam, causing the residual portion 36 a to solidify while moving in an axial direction L of the first wire 26 a and a direction M that crosses the axial direction L (see FIG. 8B), and causing the distal end of the first wire 26 a to wrap around the side surface of the second wire 26 b at the intersection 30 (see FIG. 8C).
As illustrated in FIGS. 8A to 8C, the first wire 26 a can be welded to the second wire 26 b at the intersection 30 while forming the bulging portion 57 at the distal end of the first wire 26 a. Therefore, the step of welding the first and second wires 26 a and 26 b together at the intersection 30 before cutting off the excess portions of the first and second wires. 26 a and 26 b can be omitted. As a result, the manufacturing cost of the catheter 1 can be reduced.
As described above, the bulging portions 27, 37, and 47 are provided at the distal end of the braid 26. Thus, the distal ends of either or both of the first wires 26 a and the second wires 26 b that have been cut into a sharp shape are not left untreated, and the risk that the braid 26 will penetrate the tip 12 can be reduced. In addition, the bulging portions 27, 37, and 47 provided at the distal end of the braid 26 serve as anchors on the tip 12, so that the risk that the tip 12 will be pulled off from the catheter shaft 10 can also be reduced.
1. A catheter comprising:
a catheter shaft including;
an inner layer;
a braid disposed on an outer periphery of the inner layer, the braid including (i) a plurality of first wires and a plurality of second wires that are woven together, and (ii) a plurality of first bulging portions disposed on corresponding distal ends of the plurality of first wires; and
an outer layer disposed on an outer periphery of the braid; and
a tip disposed on a distal end of the catheter shaft, the tip covering the plurality of first bulging portions,
wherein each of the plurality of first bulging portions is disposed at a position distally shifted from an intersection that each of the plurality of first wires and each of the plurality of second wire are intersected.
2. The catheter according to claim 1, further comprising:
a plurality of second bulging portions disposed on corresponding distal ends of the plurality of second wires,
wherein each of the plurality of second bulging portions is larger than each of the plurality of first bulging portions.
3. The catheter according to claim 2, wherein each of the plurality of second bulging portions is disposed at the intersection.
4. The catheter according to claim 2, wherein each of the plurality of second bulging portions is disposed at a position proximally shifted from each of the plurality of first bulging portions.
5. The catheter according to claim 1, wherein a radial thickness of each of the plurality of first bulging portions is larger than a radial thickness of each of the plurality of first wires.
6. The catheter according to claim 2, wherein a radial thickness of each of the plurality of second bulging portions is larger than a radial thickness of each of the plurality of second wires.
7. A catheter comprising:
a braid disposed on an outer periphery of the inner layer, the braid including (i) a first wire and a second wire that are woven together, and (ii) a first bulging portion disposed on a distal end of the first wire; and
a tip disposed on a distal end of the catheter shaft, the tip covering the first bulging portion,
wherein the first bulging portion is disposed at a position distally shifted from an intersection that the first wire and the second wire are intersected.
8. The catheter according to claim 7, further comprising:
a second bulging portion disposed on a distal end of second wire,
wherein the second bulging portion is larger than the first bulging portion.
9. The catheter according to claim 8, wherein the second bulging portion is disposed at the intersection.
10. The catheter according to claim 8, wherein the second bulging portion is disposed at a position proximally shifted from the first bulging portion.
11. The catheter according to claim 7, wherein a radial thickness of the first bulging portion is larger than a radial thickness of the first wire.
12. The catheter according to claim 8, wherein a radial thickness of the second bulging portion is larger than a radial thickness of the second wire.
US15358262 2013-01-30 2016-11-22 Catheter Active US9999749B2 (en)
JP2013-015013 2013-01-30
JP2013015013A JP6080258B2 (en) 2013-01-30 2013-01-30 catheter
US14100943 US9545496B2 (en) 2013-01-30 2013-12-09 Catheter
US15358262 US9999749B2 (en) 2013-01-30 2016-11-22 Catheter
US14100943 Continuation US9545496B2 (en) 2013-01-30 2013-12-09 Catheter
US20170072166A1 true US20170072166A1 (en) 2017-03-16
US9999749B2 true US9999749B2 (en) 2018-06-19
ID=50000809
US14100943 Active 2034-10-26 US9545496B2 (en) 2013-01-30 2013-12-09 Catheter
US15358262 Active US9999749B2 (en) 2013-01-30 2016-11-22 Catheter
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JP (1) JP6080258B2 (en)
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