Source: http://www.science.gov/topicpages/a/additional+department+regulations.html
Timestamp: 2016-10-25 05:07:24
Document Index: 478843453

Matched Legal Cases: ['art 84', 'art 91', '§ 57', 'art 80', 'art 83', 'art 76', 'art 80', 'art 83', '§ 21', '§ 52', '§ 52', 'art 0', '§ 52', '§ 52', '§ 52', '§ 21', '§ 21', '§ 291', '§ 291', '§ 291', '§ 291', '§ 291', 'art 80', 'arts 781', 'arts 120', '§ 65', '§ 65', '§ 65', '§ 65', '§ 65', 'art 80', 'art 80', '§ 1812', 'art 1', 'art 345', 'art 345', '§ 260', '§ 260', '§ 260', '§ 260', 'art 50', 'art 16', 'art 74', 'art 75', 'art 305', 'art 1915', 'art 306', 'art 306', 'art 306', 'art 306', 'art 306', 'art 1915', 'arts 74', '§ 100', 'art 36', 'arts 74', '§ 0', 'art 1915', '§ 453', '§ 1738', '§ 1944', 'art 2634', 'art 2635', 'art 8', 'art 230', 'art 280', 'art 80', 'art 305', '§ 301', '§ 301', 'art 305', 'art: 45', 'art 16', 'art 46', 'art 74', 'art 280', 'art 75', '§ 389', '§ 548', '§ 548', '§ 548', '§ 548']

additional department regulations: Topics by Science.gov
Sample records for additional department regulations
42 CFR 57.216 - What additional Department regulations apply to schools?
... 42 Public Health 1 2014-10-01 2014-10-01 false What additional Department regulations apply to schools? 57.216 Section 57.216 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Health Professions Student...
... of the Public Health Service Act 45 CFR part 84—Nondiscrimination on the basis of handicap in... financial assistance 45 CFR part 91—Nondiscrimination on the basis of age in Health and Human Services... STUDENT LOANS Health Professions Student Loans § 57.216 What additional Department regulations apply...
42 CFR 57.316 - What additional Department regulations apply to schools?
... regulations, several other regulations apply under this subpart. These include, but are not limited to: 45 CFR... Drug-Free Workplace (Grants) 45 CFR part 80—Nondiscrimination under programs receiving Federal... Act of 1964 45 CFR part 83—Regulation for the administration and enforcement of sections 794 and...
... limited to: 45 CFR part 76—Governmentwide Debarment and Suspension (nonprocurement) and Governmentwide Requirements for Drug-Free Workplace (Grants) 45 CFR part 80—Nondiscrimination under programs receiving Federal... Act of 1964 45 CFR part 83—Regulation for the administration and enforcement of sections 794 and...
38 CFR 21.8380 - Additional applicable regulations.
... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Additional applicable regulations. 21.8380 Section 21.8380 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Training and Rehabilitation for...
... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Additional applicable regulations. 21.8380 Section 21.8380 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Training and Rehabilitation for Certain Children of Vietnam Veterans and...
... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Definitions of terms used in the Additional Protocol Regulations (APR). 781.1 Section 781.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS...
... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Definitions of terms used in the Additional Protocol Regulations (APR). 781.1 Section 781.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS...
... 15 Commerce and Foreign Trade 2 2012-01-01 2012-01-01 false Definitions of terms used in the Additional Protocol Regulations (APR). 781.1 Section 781.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS...
... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Definitions of terms used in the Additional Protocol Regulations (APR). 781.1 Section 781.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS...
... Children of Vietnam Veterans and Veterans with Covered Service in Korea-Spina Bifida and Covered Birth Defects Additional Applicable Regulations § 21.8380 Additional applicable regulations. The...
40 CFR 52.583 - Additional rules and regulations.
... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Georgia> § 52.583 Additional rules and... more stringent than those otherwise applicable under the currently approved Georgia regulations....
... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Georgia § 52.583 Additional rules and... more stringent than those otherwise applicable under the currently approved Georgia regulations....
48 CFR 803.101-3 - Department regulations.
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Department regulations. 803.101-3 Section 803.101-3 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Safeguards 803.101-3 Department regulations. (a) Part 0 of 38 Code of...
... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Additional rules and regulations. 52.583 Section 52.583 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Georgia> § 52.583 Additional rules...
... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Additional rules and regulations. 52.583 Section 52.583 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Georgia § 52.583 Additional rules...
... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Additional rules and regulations. 52.583 Section 52.583 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Georgia § 52.583 Additional rules...
38 CFR 21.6380 - Additional applicable Chapter 31 regulations.
... vocational training under this program in the same manner as they apply to 38 U.S.C. chapter 31: § 21.380... VETERANS AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Temporary Program of Vocational Training for Certain New Pension Recipients Additional Applicable Regulations § 21.6380...
Self-Regulation While Practicing Addition Facts on the Microcomputer.
Schultz, Karen A.
The purpose of the study was to survey self-regulation while responding to the addition facts. First graders' performance on microcomputer practice exercises was observed and recorded. Subjects could choose an analytic mode of operation using a symbolic or a finger strategy; or, they could choose a geometric mode of operation using a pictorial or…
Disclosure of hydraulic fracturing fluid chemical additives: analysis of regulations.
Maule, Alexis L; Makey, Colleen M; Benson, Eugene B; Burrows, Isaac J; Scammell, Madeleine K
Hydraulic fracturing is used to extract natural gas from shale formations. The process involves injecting into the ground fracturing fluids that contain thousands of gallons of chemical additives. Companies are not mandated by federal regulations to disclose the identities or quantities of chemicals used during hydraulic fracturing operations on private or public lands. States have begun to regulate hydraulic fracturing fluids by mandating chemical disclosure. These laws have shortcomings including nondisclosure of proprietary or "trade secret" mixtures, insufficient penalties for reporting inaccurate or incomplete information, and timelines that allow for after-the-fact reporting. These limitations leave lawmakers, regulators, public safety officers, and the public uninformed and ill-prepared to anticipate and respond to possible environmental and human health hazards associated with hydraulic fracturing fluids. We explore hydraulic fracturing exemptions from federal regulations, as well as current and future efforts to mandate chemical disclosure at the federal and state level. PMID:23552653
48 CFR 222.403-4 - Department of Labor regulations.
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Department of Labor regulations. 222.403-4 Section 222.403-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO...
... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Department of Labor regulations. 222.403-4 Section 222.403-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO...
... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Department of Labor regulations. 222.403-4 Section 222.403-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO...
... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Department of Labor regulations. 222.403-4 Section 222.403-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO...
... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Department of Labor regulations. 222.403-4 Section 222.403-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO...
Fuel additive programs at crossroads of regulation, market dynamics
Fuel additive manufacturers, gasoline marketers and automakers seem to be forgetting about the power of the marketplace in their efforts to use additives to help reduce emissions and improve vehicle performance. Recall that the port fuel injector (PFI) and intake valve deposit (IVD) problems of the 1980s were addressed quickly by the fuels industry. In just a few months after the PFID problem surfaced, additive makers had detergents on the market, and fuel marketers followed up with an effective advertising campaign. Formal regulations came about a decade later. The solution to the BMW IVD problem was similar. BMW provided an enticing incentive for oil companies to differentiate through better additives and many did. Contrast those developments with the command-and-control approach that has been in effect since January 1995. EPA`s additive rule is working almost to perfection - if adherence to strict rules is considered. All gasolines in the US are additized, and a wide variety of packages have been developed that meet the regulatory standards. But by the measure of real-world performance, the circumstances can look quite different. And with industry finalizing a better IVD test and conducting research into the need for a combustion chamber deposit (CCD) regulation, now may be the time to limit the regulatory approach and let refiners and additive suppliers return to creating products that target excellence instead of regulatory minimums.
14 CFR 291.24 - Waiver of Department Economic Regulations.
... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Waiver of Department Economic Regulations... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION General Rules for All-Cargo Air Transportation § 291.24 Waiver of Department Economic Regulations. Except for...
... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Waiver of Department Economic Regulations... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION General Rules for All-Cargo Air Transportation § 291.24 Waiver of Department Economic Regulations. Except for...
... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Waiver of Department Economic Regulations... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION General Rules for All-Cargo Air Transportation § 291.24 Waiver of Department Economic Regulations. Except for...
... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Waiver of Department Economic Regulations... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION General Rules for All-Cargo Air Transportation § 291.24 Waiver of Department Economic Regulations. Except for...
... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Waiver of Department Economic Regulations... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION General Rules for All-Cargo Air Transportation § 291.24 Waiver of Department Economic Regulations. Except for...
7 CFR 301.76-7 - Additional conditions for issuance of certificates and limited permits for regulated articles...
... 7 Agriculture 5 2012-01-01 2012-01-01 false Additional conditions for issuance of certificates and limited permits for regulated articles moved interstate from areas quarantined for citrus greening. 301.76-7 Section 301.76-7 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE,...
Nitrogen Addition Regulates Soil Nematode Community Composition through Ammonium Suppression
Wei, Cunzheng; Zheng, Huifen; Li, Qi; Lü, Xiaotao; Yu, Qiang; Zhang, Haiyang; Chen, Quansheng; He, Nianpeng; Kardol, Paul; Liang, Wenju; Han, Xingguo
Nitrogen (N) enrichment resulting from anthropogenic activities has greatly changed the composition and functioning of soil communities. Nematodes are one of the most abundant and diverse groups of soil organisms, and they occupy key trophic positions in the soil detritus food web. Nematodes have therefore been proposed as useful indicators for shifts in soil ecosystem functioning under N enrichment. Here, we monitored temporal dynamics of the soil nematode community using a multi-level N addition experiment in an Inner Mongolia grassland. Measurements were made three years after the start of the experiment. We used structural equation modeling (SEM) to explore the mechanisms regulating nematode responses to N enrichment. Across the N enrichment gradient, significant reductions in total nematode abundance, diversity (H' and taxonomic richness), maturity index (MI), and the abundance of root herbivores, fungivores and omnivores-predators were found in August. Root herbivores recovered in September, contributing to the temporal variation of total nematode abundance across the N gradient. Bacterivores showed a hump-shaped relationship with N addition rate, both in August and September. Ammonium concentration was negatively correlated with the abundance of total and herbivorous nematodes in August, but not in September. Ammonium suppression explained 61% of the variation in nematode richness and 43% of the variation in nematode trophic group composition. Ammonium toxicity may occur when herbivorous nematodes feed on root fluid, providing a possible explanation for the negative relationship between herbivorous nematodes and ammonium concentration in August. We found a significantly positive relationship between fungivores and fungal phospholipid fatty acids (PLFA), suggesting bottom-up control of fungivores. No such relationship was found between bacterivorous nematodes and bacterial PLFA. Our findings contribute to the understanding of effects of N enrichment in
77 FR 699 - Regulation of Fuels and Fuel Additives: Identification of Additional Qualifying Renewable Fuel...
... regulation that were proposed on July 1, 2011(76 FR 38844). The first change adds ID letters to pathways to... an evaluation of renewable gasoline and renewable gasoline blendstocks, as well as biodiesel from... fuels such as ethanol and biodiesel. Regulated categories and entities affected by this action...
77 FR 13009 - Regulation of Fuels and Fuel Additives: Identification of Additional Qualifying Renewable Fuel...
... on January 5, 2012 (77 FR 700) to amend the Renewable Fuel Standard program regulations. The... direct final rule published at 77 FR 700, on January 5, 2012. FOR FURTHER INFORMATION CONTACT: Vincent... rule also published on January 5, 2012 (77 FR 462). As stated in the direct final rule and the...
Biogas Production on Demand Regulated by Butyric Acid Addition
Kasper, K.; Schiffels, J.; Krafft, S.; Kuperjans, I.; Elbers, G.; Selmer, T.
Investigating effects of volatile fatty acids on the biogas process it was observed that butyric acid can be used for transient stimulation of the methane production in biogas plants operating with low energy substrates like cattle manure. Upon addition of butyrate the methane output of the reactors doubled within 24 h and reached almost 3-times higher methane yields within 3-4 days. Butyrate was quantitatively eliminated and the reactors returned to the original productivity state within 3 days when application of butyrate was stopped. The opportunity to use butyrate feeding for increased biogas production on demand is discussed.
Wishau, R.J.; Dawson, J.; Lee, D.W.
76 FR 37703 - Regulation of Fuels and Fuel Additives: 2012 Renewable Fuel Standards; Public Hearing
... AGENCY 40 CFR Part 80 RIN 2060-AQ76 Regulation of Fuels and Fuel Additives: 2012 Renewable Fuel Standards.... SUMMARY: The EPA is announcing a public hearing to be held for the proposed rule ``Regulation of Fuels and Fuel Additives: 2012 Renewable Fuel Standards,'' which EPA intends to publish separately in the...
... CFR parts 781 to 786 that were promulgated by the Department of Commerce to implement and enforce the... Weapons (NPT). ITAR. The International Traffic in Arms Regulations (22 CFR Parts 120-130), which are... United States of America and the International Atomic Energy Agency for the Application of Safeguards...
22 CFR 65.4 - Copies of regulations to Department of State.
... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Copies of regulations to Department of State. 65.4 Section 65.4 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES FOREIGN STUDENTS § 65.4 Copies of regulations to Department of State. In order to enable the Secretary of State...
... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Copies of regulations to Department of State. 65.4 Section 65.4 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES FOREIGN STUDENTS § 65.4 Copies of regulations to Department of State. In order to enable the Secretary of State...
... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Copies of regulations to Department of State. 65.4 Section 65.4 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES FOREIGN STUDENTS § 65.4 Copies of regulations to Department of State. In order to enable the Secretary of State...
... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Copies of regulations to Department of State. 65.4 Section 65.4 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES FOREIGN STUDENTS § 65.4 Copies of regulations to Department of State. In order to enable the Secretary of State...
... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Copies of regulations to Department of State. 65.4 Section 65.4 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES FOREIGN STUDENTS § 65.4 Copies of regulations to Department of State. In order to enable the Secretary of State...
78 FR 12005 - Regulation of Fuels and Fuel Additives: 2013 Renewable Fuel Standards; Public Hearing
... separately in the Federal Register on February 7, 2013. (78 FR 9282.) The hearing will be held in Ann Arbor... at 78 FR 9282, February 7, 2013. Public Hearing: The public hearing will provide interested parties... AGENCY 40 CFR Part 80 RIN 2060-AR43 Regulation of Fuels and Fuel Additives: 2013 Renewable Fuel...
76 FR 18066 - Regulation of Fuels and Fuel Additives: Changes to Renewable Fuel Standard Program
... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 80 Regulation of Fuels and Fuel Additives: Changes to Renewable Fuel Standard Program... producers and importers of renewable fuels for which RINs have been generated by the foreign...
Midorikawa, Keiko; Kuroda, Masaharu; Terauchi, Kaede; Hoshi, Masako; Ikenaga, Sachiko; Ishimaru, Yoshiro; Abe, Keiko; Asakura, Tomiko
The balance between carbon and nitrogen is a key determinant of seed storage components, and thus, is of great importance to rice and other seed-based food crops. To clarify the influence of the rhizosphere carbon/nitrogen balance during the maturation stage of several seed components, transcriptome analysis was performed on the seeds from rice plants that were provided additional nitrogen fertilization at heading time. As a result, it was assessed that genes associated with molecular processes such as photosynthesis, trehalose metabolism, carbon fixation, amino acid metabolism, and cell wall metabolism were differentially expressed. Moreover, cellulose and sucrose synthases, which are involved in cellulose synthesis, were down-regulated. Therefore, we compared cellulose content of mature seeds that were treated with additional nitrogen fertilization with those from control plants using calcofluor staining. In these experiments, cellulose content in endosperm from plants receiving additional nitrogen fertilization was less than that in control endosperm. Other starch synthesis-related genes such as starch synthase 1, starch phosphorylase 2, and branching enzyme 3 were also down-regulated, whereas some α-amylase and β-amylase genes were up-regulated. On the other hand, mRNA expression of amino acid biosynthesis-related molecules was up-regulated. Moreover, additional nitrogen fertilization caused accumulation of storage proteins and up-regulated Cys-poor prolamin mRNA expression. These data suggest that additional nitrogen fertilization at heading time changes the expression of some storage substance-related genes and reduces cellulose levels in endosperm. PMID:24905454
Chondroitin sulfate addition to CD44H negatively regulates hyaluronan binding
Ruffell, Brian; Johnson, Pauline . E-mail: pauline@interchange.ubc.ca
CD44 is a widely expressed cell adhesion molecule that binds hyaluronan, an extracellular matrix glycosaminoglycan, in a tightly regulated manner. This regulated interaction has been implicated in inflammation and tumor metastasis. CD44 exists in the standard form, CD44H, or as higher molecular mass isoforms due to alternative splicing. Here, we identify serine 180 in human CD44H as the site of chondroitin sulfate addition and show that lack of chondroitin sulfate addition at this site enhances hyaluronan binding by CD44. A CD44H-immunoglobulin fusion protein expressed in HEK293 cells, and CD44H expressed in murine L fibroblast cells were modified by chondroitin sulfate, as determined by reduced sulfate incorporation after chondroitinase ABC treatment. Mutation of serine 180 or glycine 181 in CD44H reduced chondroitin sulfate addition and increased hyaluronan binding, indicating that serine 180 is the site for chondroitin sulfate addition in CD44H and that this negatively regulates hyaluronan binding.
45 CFR 1340.3 - Applicability of Department-wide regulations.
... 45 Public Welfare 4 2013-10-01 2013-10-01 false Applicability of Department-wide regulations. 1340.3 Section 1340.3 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, CHILD ABUSE AND NEGLECT...
43 CFR 1812.1-1 - Regulations governing practice before the Department.
... Department. 1812.1-1 Section 1812.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued... GUIDANCE Qualifications of Practitioners § 1812.1-1 Regulations governing practice before the Department..., must comply with the requirements of part 1 of this title....
77 FR 50454 - Department of the Treasury Acquisition Regulations; Contract Clause on Minority and Women...
...The Department of the Treasury (the Department) is proposing to amend the Department of the Treasury Acquisition Regulation (DTAR) to include a contract clause on minority and women inclusion, as required by the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010 (the Dodd-Frank...
Additive to regulate the perovskite crystal film growth in planar heterojunction solar cells
Song, Xin; Sun, Po; Chen, Zhi-Kuan E-mail: iamzkchen@njtech.edu.cn; Wang, Weiwei; Ma, Wanli E-mail: iamzkchen@njtech.edu.cn
We reported a planar heterojunction perovskite solar cell fabricated from MAPbI{sub 3−x}Cl{sub x} perovskite precursor solution containing 1-chloronaphthalene (CN) additive. The MAPbI{sub 3−x}Cl{sub x} perovskite films have been characterized by UV-vis, SEM, XRD, and steady-state photoluminescence (PL). UV-vis absorption spectra measurement shows that the absorbance of the film with CN additive is significantly higher than the pristine film and the absorption peak is red shift by 30 nm, indicating the perovskite film with additive possessing better crystal structures. In-situ XRD study of the perovskite films with additive demonstrated intense diffraction peaks from MAPbI{sub 3−x}Cl{sub x} perovskite crystal planes of (110), (220), and (330). SEM images of the films with additive indicated the films were more smooth and homogenous with fewer pin-holes and voids and better surface coverage than the pristine films. These results implied that the additive CN is beneficial to regulate the crystallization transformation kinetics of perovskite to form high quality crystal films. The steady-state PL measurement suggested that the films with additive contained less charge traps and defects. The planar heterojunction perovskite solar cells fabricated from perovskite precursor solution containing CN additive demonstrated 30% enhancement in performance compared to the devices with pristine films. The improvement in device efficiency is mainly attributed to the good crystal structures, more homogenous film morphology, and also fewer trap centers and defects in the films with the additive.
U.S. Department of Education's Proposed FERPA Regulations: Overview and Initial Analysis
On April 8, 2011, the U.S. Department of Education (USED) published in the Federal Register new proposed amendments to regulations implementing the Family Educational Rights and Privacy Act (FERPA). The notice invites public comments on the proposed regulations, which are due no later than May 23, 2011. The proposed regulations are designed to…
Removal of Regulations. Final Regulations. Federal Register, Department of Education, 34 CFR Part 345
National Archives and Records Administration, 2004
The Secretary amends the Code of Federal Regulations (CFR) to remove obsolete regulations. As a result of the enactment of the Assistive Technology Act of 1998, these regulations are no longer needed. The Secretary therefore takes this action to remove the regulations. Part 345 is removed effective March 25, 2004.
Transition from a plasmid to a chromosomal mode of replication entails additional regulators
Venkova-Canova, Tatiana; Chattoraj, Dhruba K.
Plasmid origins of replication are rare in bacterial chromosomes, except in multichromosome bacteria. The replication origin of Vibrio cholerae chromosome II (chrII) closely resembles iteron-bearing plasmid origins. Iterons are repeated initiator binding sites in plasmid origins and participate both in replication initiation and its control. The control is mediated primarily by coupling of iterons via the bound initiators (“handcuffing”), which causes steric hindrance to the origin. The control in chrII must be different, since the timing of its replication is cell cycle-specific, whereas in plasmids it is random. Here we show that chrII uses, in addition to iterons, another kind of initiator binding site, named 39-mers. The 39-mers confer stringent control by increasing handcuffing of iterons, presumably via initiator remodeling. Iterons, although potential inhibitors of replication themselves, restrain the 39-mer–mediated inhibition, possibly by direct coupling (“heterohandcuffing”). We propose that the presumptive transition of a plasmid to a chromosomal mode of control requires additional regulators to increase the stringency of control, and as will be discussed, to gain the capacity to modulate the effectiveness of the regulators at different stages of the cell cycle. PMID:21444815
76 FR 20249 - Department of State Acquisition Regulation
... published a proposed rule, Public Notice 5992 at 72 FR 64980, November 19, 2007, with a request for comments... 71 FR 208, January 3, 2006). As specified in the proposed rule, the DOSAR clause directs contractors... regulation to ensure its consistency with the regulatory philosophy and principles set forth in...
15 CFR 30.18 - Department of State regulations.
... information, when required, for items on the USML of the ITAR (22 CFR 121). Information for items identified... export. (b) Refer to the ITAR 22 CFR 120-130 for requirements regarding information required for... State regulations can be found at http://www.state.gov....
Department of Energy Efforts to Promote Universal Adherence to the IAEA Additional Protocol
Killinger, Mark H.; Hansen, Linda H.; Kovacic, Don N.; VanSickle, Matthew; Apt, Kenneth E.
Entry-into-force of the U.S. Additional Protocol (AP) in January 2009 continues to demonstrate the ongoing commitment by the United States to promote universal adherence to the AP. The AP is a critical tool for improving the International Atomic Energy Agency’s (IAEA) capabilities to detect undeclared activities that indicate a clandestine nuclear weapons program. This is because States Parties are required to provide information about, and access to, nuclear fuel cycle activities beyond their traditional safeguards reporting requirements. As part of the U.S. AP Implementation Act and Senate Resolution of Ratification, the Administration is required to report annually to Congress on measures taken to achieve the adoption of the AP in non-nuclear weapon states, as well as assistance to the IAEA to promote the effective implementation of APs in those states. A key U.S. effort in this area is being managed by the International Nuclear Safeguards and Engagement Program (INSEP) of the U.S. Department of Energy (DOE). Through new and existing bilateral cooperation agreements, INSEP has initiated technical assistance projects for AP implementation with selected non-weapon states. States with which INSEP is currently cooperating include Vietnam and Thailand, with Indonesia, Algeria, Morocco, and other countries as possible future collaborators in the area of AP implementation. The INSEP collaborative model begins with a joint assessment with our partners to identify specific needs they may have regarding entering the AP into force and any impediments to successful implementation. An action plan is then developed detailing and prioritizing the necessary joint activities. Such assistance may include: advice on developing legal frameworks and regulatory documents; workshops to promote understanding of AP requirements; training to determine possible declarable activities; assistance in developing a system to collect and submit declarations; performing industry outreach to
... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Additional regulation of certain hazardous waste recycling activities on a case-by-case basis. 260.40 Section 260.40 Protection of... SYSTEM: GENERAL Rulemaking Petitions § 260.40 Additional regulation of certain hazardous waste...
... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Additional regulation of certain hazardous waste recycling activities on a case-by-case basis. 260.40 Section 260.40 Protection of... SYSTEM: GENERAL Rulemaking Petitions § 260.40 Additional regulation of certain hazardous waste...
... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Additional regulation of certain hazardous waste recycling activities on a case-by-case basis. 260.40 Section 260.40 Protection of... SYSTEM: GENERAL Rulemaking Petitions § 260.40 Additional regulation of certain hazardous waste...
... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Additional regulation of certain hazardous waste recycling activities on a case-by-case basis. 260.40 Section 260.40 Protection of... SYSTEM: GENERAL Rulemaking Petitions § 260.40 Additional regulation of certain hazardous waste...
RNA polymerase pausing regulates translation initiation by providing additional time for TRAP-RNA interaction.
Yakhnin, Alexander V; Yakhnin, Helen; Babitzke, Paul
RNA polymerase (RNAP) pause sites have been identified in several prokaryotic genes. Although the presumed biological function of RNAP pausing is to allow synchronization of RNAP position with regulatory factor binding and/or RNA folding, a direct causal link between pausing and changes in gene expression has been difficult to establish. RNAP pauses at two sites in the Bacillus subtilis trpEDCFBA operon leader. Pausing at U107 and U144 participates in transcription attenuation and trpE translation control mechanisms, respectively. Substitution of U144 caused a substantial pausing defect in vitro and in vivo. These mutations led to increased trp operon expression that was suppressed by overproduction of TRAP, indicating that pausing at U144 provides additional time for TRAP to bind to the nascent transcript and promote formation of an RNA structure that blocks translation of trpE. These results establish that pausing is capable of playing a role in regulating translation in bacteria. PMID:17114058
Serum Potassium and Glucose Regulation in the ADDITION-Leicester Screening Study
Carter, Patrice; Bodicoat, Danielle H.; Quinn, Lauren M.; Zaccardi, Francesco; Webb, David R.; Khunti, Kamlesh; Davies, Melanie J.
Introduction. Previous observational studies have shown conflicting results between plasma K+ concentrations and risk of type 2 diabetes. To help clarify the evidence we aimed to determine whether an association existed between serum K+ and glucose regulation within a UK multiethnic population. Methods. Participants were recruited as part of the ADDITION Leicester study, a population based screening study. Individuals from primary care between the age of 40 and 75 years if White European or 25 and 75 years if South Asian or Afro Caribbean were recruited. Tests for associations between baseline characteristics and K+ quartiles were conducted using linear regression models. Results. Data showed individuals in the lowest K+ quartile had significantly greater 2-hour glucose levels (0.53 mmol/L, 95% CI: 0.36 to 0.70, P ≤ 0.001) than those in the highest K+ quartile. This estimation did not change with adjustment for potential confounders. Conversely, participants in the lowest K+ quartile had a 0.14% lower HbA1c (95% CI −0.19 to −0.10: P ≤ 0.001) compared to those in the highest K+ quartile. Conclusion. This cross-sectional analysis demonstrated that lower K+ was associated with greater 2 hr glucose. The data supports the possibility that K+ may influence glucose regulation and further research is warranted. PMID:25883988
Graduate and professional study fellowships--Department of Education. Final regulations with invitation to comment.
The Secretary issues final regulations for the Graduate and Professional Study Fellowships Program. The regulations, which implement Title IX, Part B of the Higher Education Act of 1965, have been amended to reflect the statutory changes in the Education Amendments of 1980 and to reflect changes required by the Education Department General Administrative Regulations (EDGAR). These regulations specify the selection criteria the Secretary uses in evaluating applications for fellowships for graduate and professional study, public service education, and studies in domestic mining and mineral and mineral fuel conservation. These regulations also describe application procedures, eligibility requirements, and the terms and conditions of an award. PMID:10249535
42 CFR 65.8 - What additional Department regulations apply to grantees?
... policies apply to grants under this part. These include, but are not limited to: 42 CFR part 50, subpart D—Public Health Service grant appeals procedure. 45 CFR part 16—Procedures of the Departmental Grant Appeals Board. 45 CFR part 74—Administration of grants. 45 CFR part 75—Informal grant appeals...
Critical Review of Public Health Regulations of Titanium Dioxide, a Human Food Additive
From 1916 to 2011, an estimated total of 165 050 000 metric tons of titanium dioxide (TiO2) pigment were produced worldwide. Current safety regulations on the usage of the TiO2 pigment as an inactive ingredient additive in human food are based on legislation from 1969 and are arguably outdated. This article compiles new research results to provide fresh data for potential risk reassessment. However, even after 45 years, few scientific research reports have provided truly reliable data. For example, administration of very high doses of TiO2 is not relevant to daily human uptake. Nevertheless, because dose makes the poison, the literature provides a valuable source for understanding potential TiO2 toxicity after oral ingestion. Numerous scientific articles have observed that TiO2 can pass and be absorbed by the mammalian gastrointestinal tract; can bioconcentrate, bioaccumulate, and biomagnify in the tissues of mammals and other vertebrates; has a very limited elimination rate; and can cause histopathological and physiological changes in various organs of animals. Such action is contrary to the 1969 decision to approve the use of TiO2 as an inactive ingredient in human food without an established acceptable daily intake, stating that neither significant absorption nor tissue storage following ingestion of TiO2 was possible. Thus, relevant governmental agencies should reassess the safety of TiO2 as an additive in human food and consider establishing an acceptable maximum daily intake as a precautionary measure. Integr Environ Assess Manag 2015;11:10–20. © 2014 The Author. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of SETAC. PMID:25091211
75 FR 26049 - Regulation of Fuels and Fuel Additives: Modifications to Renewable Fuel Standard Program
... Standard program regulations that were published on March 26, 2010, at 75 FR 14670 (the ``RFS2 regulations... the Renewable Fuel Standard regulations published on March 26, 2010, at 75 FR 14670 (the ``RFS2..., (58 FR 51735 (October 4, 1993)) the Agency must determine whether the regulatory action...
75 FR 79964 - Regulation of Fuels and Fuel Additives: Modifications to Renewable Fuel Standard Program
...EPA is finalizing amendments to certain of the Renewable Fuel Standard program regulations that were published on March 26, 2010, and that took effect on July 1, 2010 (``the RFS2 regulations''). Following publication of the RFS2 regulations, promulgated in response to the requirements of the Energy Independence and Security Act of 2007, EPA discovered some technical errors and areas within the......
77 FR 75868 - Regulation of Fuels and Fuel Additives: Modifications to the Transmix Provisions Under the Diesel...
..., 77 FR 61281, October 9, 2012. Regulation of Fuels and Fuel Additives: Modifications to Renewable Fuel Standard and Diesel Sulfur Programs, Notice of Proposed Rule, 77 FR 61313, October 9, 2012. \\3\\ Regulation..., Withdrawal of direct final rule, 77 FR 72746, December 6, 2012. In response to industry input, EPA...
... CFR part 305 of this chapter. (2) The nursery stock is inspected by an inspector in accordance with... limited permits for regulated articles moved interstate from areas quarantined for citrus greening. 301.76... PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus...
Regulation of Soil Microbial Carbon-use Efficiency by Soil Moisture, Substrate Addition, and Incubation Time
Microbial carbon-use efficiency (CUE) is a key variable in biogeochemical cycling that regulates soil C sequestration, greenhouse gas emissions, and retention of inorganic nutrients. Microbial CUE is the fraction of C converted to biomass rather than respired as CO2. Biogeochemical models have been shown to be highly sensitive to variation in CUE; however, we currently have a poor understanding of how CUE responds to environmental variables such as soil moisture and nutrient limitations. We examined the effect of soil moisture and C supply on CUE in soil from a western hemlock / sitka spruce forest in Oregon, USA, using a novel technique which supplies 13C and 15N substrates through the gas phase so that water addition is not necessary. Soil samples (28 g oven-dry equiv. wt) at two water potentials (-0.03 and -3.55 MPa) were exposed to 13C-acetic acid vapor for either 6 or 30 sec to provide two different concentrations of acetate to soil microbial communities. The soils were also injected with small amounts of 15NH3 gas to allow quantification of microbial N assimilation rates and to provide an alternate method of calculating CUE. Rates of 13CO2 respiration were measured continuously during a 48-h incubation using cavity ring-down spectroscopy. Soil samples were extracted at seven time intervals (0, 0.5, 1.5, 4.5, 12, 24, and 48 h) in 0.5 M K2SO4 and analyzed for DO13C, microbial 13C, DO15N, inorganic 15N, and microbial 15N to calculate how gross rates of C and N assimilation and microbial CUE change with incubation time. As expected, microbial C and N assimilation rates and CUE increased with soil moisture and the quantity of acetate added; however, C:N assimilated was higher at lower soil moisture, suggesting that either C-storage compounds were being created, or that fungal communities were responsible for a greater proportion of the assimilation in drier soils. Assimilation rates and CUE also changed with incubation time, demonstrating that estimates of CUE
75 FR 26165 - Regulation of Fuels and Fuel Additives: Alternative Affirmative Defense Requirements for Ultra...
...EPA is issuing a proposed rule to amend the diesel sulfur regulations to allow refiners, importers, distributors, and retailers of highway diesel fuel the option to use an alternative affirmative defense if the Agency finds highway diesel fuel samples above the specified sulfur standard at retail facilities. This rule also proposes to amend the gasoline benzene regulations to allow......
75 FR 26025 - Regulation of Fuels and Fuel Additives: Modifications to Renewable Fuel Standard Program
... certain of the Renewable Fuel Standard regulations published on March 26, 2010, at 75 FR 14670 (the ``RFS2... Executive Order 12866, (58 FR 51735 (October 4, 1993)) the Agency must determine whether the regulatory..., or renewable fuels such as ethanol and biodiesel. Regulated categories and entities affected by...
.... SUPPLEMENTARY INFORMATION: Need for Correction On March 19, 2012 (77 FR 15976), the Food Safety and Inspection... rule to amend the meat and poultry products regulations pertaining to the schedule of operations....
... Rule on Changes to the Schedule of Operations Regulations (76 FR page 33979), if meat and poultry...). Executive Order 13563 emphasizes the importance of quantifying both costs and benefits, of reducing...
48 CFR 1252.217-80 - Department of Labor Safety and Health Regulations for Ship Repairing.
... Repairing. As prescribed at (TAR) 48 CFR 1217.7001(b) and (c), insert the following clause: Department of Labor Safety and Health Regulations for Ship Repair (APR 2005) Nothing contained in this contract shall... Shipyard Employment (29 CFR part 1915); or (c) Any other applicable Federal, State, and local laws,...
39 CFR 760.1 - Treasury Department regulations; applicability to Postal Service.
... Circular No. 300, 31 CFR part 306 (other than subpart O), as amended from time to time, shall apply insofar... 39 Postal Service 1 2014-07-01 2014-07-01 false Treasury Department regulations; applicability to Postal Service. 760.1 Section 760.1 Postal Service UNITED STATES POSTAL SERVICE POSTAL SERVICE...
... Circular No. 300, 31 CFR part 306 (other than subpart O), as amended from time to time, shall apply insofar... 39 Postal Service 1 2010-07-01 2010-07-01 false Treasury Department regulations; applicability to Postal Service. 760.1 Section 760.1 Postal Service UNITED STATES POSTAL SERVICE POSTAL SERVICE...
... Circular No. 300, 31 CFR part 306 (other than subpart O), as amended from time to time, shall apply insofar... 39 Postal Service 1 2011-07-01 2011-07-01 false Treasury Department regulations; applicability to Postal Service. 760.1 Section 760.1 Postal Service UNITED STATES POSTAL SERVICE POSTAL SERVICE...
... Circular No. 300, 31 CFR part 306 (other than subpart O), as amended from time to time, shall apply insofar... 39 Postal Service 1 2012-07-01 2012-07-01 false Treasury Department regulations; applicability to Postal Service. 760.1 Section 760.1 Postal Service UNITED STATES POSTAL SERVICE POSTAL SERVICE...
... Circular No. 300, 31 CFR part 306 (other than subpart O), as amended from time to time, shall apply insofar... 39 Postal Service 1 2013-07-01 2013-07-01 false Treasury Department regulations; applicability to Postal Service. 760.1 Section 760.1 Postal Service UNITED STATES POSTAL SERVICE POSTAL SERVICE...
... Shipyard Employment (29 CFR part 1915); or (c) Any other applicable Federal, State, and local laws, codes... Repairing. As prescribed at (TAR) 48 CFR 1217.7001(b) and (c), insert the following clause: Department of... and Health Regulations for Ship Repairing. 1252.217-80 Section 1252.217-80 Federal...
19 CFR 0.1 - Customs revenue function regulations issued under the authority of the Departments of the...
... the authority of the Departments of the Treasury and Homeland Security. 0.1 Section 0.1 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... the Departments of the Treasury and Homeland Security. (a) Regulations requiring signatures...
75 FR 34277 - Federal Acquisition Regulation; FAR Case 2008-007, Additional Requirements for Market Research
... Research AGENCIES: Department of Defense (DoD), General Services Administration (GSA), and National... executive agencies. Specifically, the head of the agency must conduct market research before issuing an... million for the procurement of items other than commercial items is required to conduct market...
77 FR 61313 - Regulation of Fuels and Fuel Additives: Modifications to Renewable Fuel Standard and Diesel...
... Additives: Changes to Renewable Fuel Standard Program, 75 FR 14670, 14681 (March 26, 2010). \\3\\ See CAA... EISA to reduce or replace the use of fossil fuels.\\4\\ \\4\\ 75 FR 14670, 14687 (March 26, 2010). The... Fuel and Fuel Additives; Changes to Renewable Fuel Standard Program,'' 75 FR 14670, available at...
... administrative activities and preparing for inspection (including preparing an inspection station and picking up... FSIS inspection program personnel to put on required gear, pick up required forms and walk to a work... March 19, 2012, FSIS proposed to amend its regulations pertaining to the schedule of operations (77...
78 FR 9281 - Regulation of Fuels and Fuel Additives: 2013 Renewable Fuel Standards
... regulatory requirements on March 26, 2010.\\1\\ \\1\\ 75 FR 14670. The volumes of renewable fuel to be used under... establishing that applicable volume on September 27, 2012.\\5\\ \\5\\ 77 FR 59458. Under 211(o)(2)(B)(ii) EPA, in... or renewable fuels such as ethanol and biodiesel. Potentially regulated categories include: NAICS...
75 FR 42237 - Regulation of Fuels and Fuel Additives: 2011 Renewable Fuel Standards
... July 1, 2010. \\1\\ 75 FR 14670. EPA is required to determine and publish the applicable annual... or renewable fuels such as ethanol and biodiesel. Potentially regulated categories include: NAICS \\1... biomass-based diesel volume of 0.8 billion gallons can be met with existing biodiesel production...
Government regulation and public opposition create high additional costs for field trials with GM crops in Switzerland.
Bernauer, Thomas; Tribaldos, Theresa; Luginbühl, Carolin; Winzeler, Michael
Field trials with GM crops are not only plant science experiments. They are also social experiments concerning the implications of government imposed regulatory constraints and public opposition for scientific activity. We assess these implications by estimating additional costs due to government regulation and public opposition in a recent set of field trials in Switzerland. We find that for every Euro spent on research, an additional 78 cents were spent on security, an additional 31 cents on biosafety, and an additional 17 cents on government regulatory supervision. Hence the total additional spending due to government regulation and public opposition was around 1.26 Euros for every Euro spent on the research per se. These estimates are conservative; they do not include additional costs that are hard to monetize (e.g. stakeholder information and dialogue activities, involvement of various government agencies). We conclude that further field experiments with GM crops in Switzerland are unlikely unless protected sites are set up to reduce these additional costs. PMID:21279684
NUTRIENT ADDITION TO RESTORE SALMON RUNS: CONSIDERATIONS FOR DEVELOPING ENVIRONMENTAL PROTECTION POLICIES AND REGULATIONS
One scheme to help restore salmon to the Pacific Northwest is the addition of nutrients (i.e., raw or processed salmon carcasses, and commercially produced organic or inorganic fertilizers) to headwaters (e.g., watersheds, lakes, or streams) that are now nutrient deficient becau...
77 FR 61281 - Regulation of Fuels and Fuel Additives: Modifications to Renewable Fuel Standard and Diesel...
... Additives: Changes to Renewable Fuel Standard Program, 75 FR 14670, 14681 (March 26, 2010). \\4\\ See CAA... EISA to reduce or replace the use of fossil fuels.\\5\\ \\5\\ 75 FR 14670, 14687 (March 26, 2010). The... Renewable Fuel Standard Program,'' 75 FR 14670, available at...
Cordle, F; Miller, S A
The increasing use of nonnutritive sweeteners and the widely publicized 1969 ban on cyclamate led to additional investigations in rodents of the carcinogenic potential of saccharin. Preliminary results of a long-term feeding study indicated formation of bladder tumors in rodents, and collective experimental evidence has demonstrated that high doses of the synthetic sweetener saccharin can cause bladder cancer in rodents. Based on the results of that and other rodent studies indicating an increased risk of bladder cancer associated with saccharin, the Commissioner of the Food and Drug Administration announced the agency's intention to propose a ban on saccharin. This intention was made known in April 1977 under the Delaney Clause of the Food, Drug, and Cosmetic Act. The clause essentially states that no additive shall be deemed safe if it is found to induce cancer in man or animals, or if it is found, after tests appropriate for the evaluation of the safety of food additives, to induce cancer in man or animals. Also in 1977, a group of epidemiologists began to assess the available epidemiologic information to determine the potential human risk. This report describes the assessment of several human epidemiologic studies available then and the results of more recent epidemiologic studies. PMID:6431484
The Role of Cocoa as a Cigarette Additive: Opportunities for Product Regulation
Kennedy, Ryan David; Connolly, Gregory N.
Introduction: The 2009 Family Smoking Prevention and Tobacco Control Act prohibited the use of characterizing flavors in cigarettes; however, some of these flavors are still used in cigarettes at varying levels. We reviewed tobacco industry internal documents to investigate the role of one of these flavors, cocoa, with the objective of understanding its relationship to sensory and risk perception, promotion of dependence, and enhancement of attractiveness and acceptability. Methods: We used the Legacy Tobacco Documents Library to identify documents relevant to our research questions. Initial search terms were generated following an examination of published literature on cocoa, other cigarette additives, and sensory and risk perception. Further research questions and search terms were generated based on review of documents generated from the initial search terms. Results: Cocoa is widely applied to cigarettes and has been used by the tobacco industry as an additive since the early 20th century. Cocoa can alter the sensory properties of cigarette smoke, including by providing a more appealing taste and decreasing its harshness. The tobacco industry has experimented with manipulating cocoa levels as a means of achieving sensory properties that appeal to women and youth. Conclusions: Although cocoa is identified as a flavor on tobacco industry Web sites, it may serve other sensory purposes in cigarettes as well. Eliminating cocoa as an additive from tobacco products may affect tobacco product abuse liability by altering smokers’ perceptions of product risk, and decreasing product appeal, especially among vulnerable populations. PMID:24610479
Education Department General Administrative Regulations. 34 CFR Parts 74, 75, 76, 77, 79, 80, 81, 82, 85 and 86.
During calendar year 1994, the U.S. Department of Education published significant revisions to the Education Department General Administrative Regulations (EDGAR). These regulatory changes addressed the noncompeting continuation (NCC) application process for discretionary grants and cooperative agreements, the Department's implementation of the…
24 CFR 52.3 - What programs and activities of the Department are subject to these regulations?
... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false What programs and activities of the Department are subject to these regulations? 52.3 Section 52.3 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development INTERGOVERNMENTAL REVIEW OF DEPARTMENT OF HOUSING...
... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false What programs and activities of the Department are subject to these regulations? 52.3 Section 52.3 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development INTERGOVERNMENTAL REVIEW OF DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT PROGRAMS...
45 CFR 100.3 - What programs and activities of the Department are subject to these regulations?
... 45 Public Welfare 1 2010-10-01 2010-10-01 false What programs and activities of the Department are subject to these regulations? 100.3 Section 100.3 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION INTERGOVERNMENTAL REVIEW OF DEPARTMENT OF HEALTH AND HUMAN SERVICES PROGRAMS AND ACTIVITIES § 100.3 What programs...
Adjustment of Civil Monetary Penalties for Inflation. Final Regulations. Federal Register, Department of Education, 34 CFR Part 36
National Archives and Records Administration, 2005
The Department of Education (Department) issued these final regulations to adjust the Department's civil monetary penalties (CMPs) for inflation. A CMP is defined in the statute as any penalty, fine, or other sanction that is: (1) for a specific monetary amount as provided by Federal law, or has a maximum amount provided for by Federal law; (2)…
Radiation safety in the nuclear medicine department: impact of the UK Ionising Radiations Regulations.
Harding, L K
The practice of nuclear medicine requires integration of radiation safety with patient care and radiopharmaceutical standards. Nationally there was useful discussion in the UK before the Ionising Radiations Regulations and Approved Code of Practice were published, although such consultation had been lacking when the Medicines Act was implemented. Most of the new considerations relating to nuclear medicine stem from Schedule 6 of the Regulations. Generally, the presence of a single patient does not require a controlled area. However, when several patients are present, or radiopharmaceuticals are being prepared prior to injection, a controlled area is required. Classification of workers is not likely to be required in a typical nuclear medicine department in the UK, although most parts of the nuclear medicine department will need to be controlled areas. These include the radiopharmacy, radionuclide dispensary, injection room, and imaging rooms if patients are injected in them. The importance of finger dose measurements is emphasised. Patient wards, however, need not be controlled areas. A particular concern in nuclear medicine was that patients should not need to be admitted to hospital merely to comply with legislation. This is possibly the case and clarification will probably be available when the Notes for Guidance are published. Most procedures in nuclear medicine departments will remain unchanged. Further information is required, however, on patient waiting rooms, handling flood sources, pregnancy, and breast feeding. Within the hospital, detailed and multidisciplinary discussion will need to take place within the forum of the radiation safety committee. PMID:3664186
34 CFR 79.3 - What programs and activities of the Department are subject to these regulations?
... the Education Consolidation and Improvement Act of 1981). (7) Research and development national in... 34 Education 1 2010-07-01 2010-07-01 false What programs and activities of the Department are subject to these regulations? 79.3 Section 79.3 Education Office of the Secretary, Department of...
DOCK2 and DOCK5 Act Additively in Neutrophils To Regulate Chemotaxis, Superoxide Production, and Extracellular Trap Formation
Watanabe, Mayuki; Terasawa, Masao; Miyano, Kei; Yanagihara, Toyoshi; Uruno, Takehito; Sanematsu, Fumiyuki; Nishikimi, Akihiko; Côté, Jean-François; Sumimoto, Hideki; Fukui, Yoshinori
Neutrophils are highly motile leukocytes that play important roles in the innate immune response to invading pathogens. Neutrophils rapidly migrate to the site of infections and kill pathogens by producing reactive oxygen species (ROS). Neutrophil chemotaxis and ROS production require activation of Rac small GTPase. DOCK2, an atypical guanine nucleotide exchange factor (GEF), is one of the major regulators of Rac in neutrophils. However, because DOCK2 deficiency does not completely abolish fMLF-induced Rac activation, other Rac GEFs may also participate in this process. In this study, we show that DOCK5 acts with DOCK2 in neutrophils to regulate multiple cellular functions. We found that fMLF- and PMA-induced Rac activation were almost completely lost in mouse neutrophils lacking both DOCK2 and DOCK5. Although β2 integrin–mediated adhesion occurred normally even in the absence of DOCK2 and DOCK5, mouse neutrophils lacking DOCK2 and DOCK5 exhibited a severe defect in chemotaxis and ROS production. Similar results were obtained when human neutrophils were treated with CPYPP, a small-molecule inhibitor of these DOCK GEFs. Additionally, we found that DOCK2 and DOCK5 regulate formation of neutrophil extracellular traps (NETs). Because NETs are involved in vascular inflammation and autoimmune responses, DOCK2 and DOCK5 would be a therapeutic target for controlling NET-mediated inflammatory disorders. PMID:25339677
Education Department General Administrative Regulations. 34 CFR Parts 74, 75, 76, 77, 79, 80, 81, 82, 85, 86, 97, 98, and 99.
This publication by the U.S. Department of Education is an unofficial version of the Department's General Administrative Regulations. The volume incorporates final regulations that the Department published too late to appear in the official July 1, 1998, version of Title 34 of the Code of Federal Regulations issued by the Office of the Federal…
48 CFR 3052.217-99 - Department of Labor safety and health regulations for ship repairing (USCG).
... at (HSAR) 48 CFR 3017.9000(a) and (b), insert the following clause: Department of Labor Safety and Health Regulations for Ship Repair (DEC 2003) Nothing contained in this contract shall relieve the... (29 U.S.C. 651, et seq.); (b) The Safety and Health Regulations for Ship Repairing (29 CFR part...
... 19 Customs Duties 1 2014-04-01 2014-04-01 false Customs revenue function regulations issued under the authority of the Departments of the Treasury and Homeland Security. 0.1 Section 0.1 Customs Duties... TRANSFERRED OR DELEGATED AUTHORITY § 0.1 Customs revenue function regulations issued under the authority...
... (29 U.S.C. 651, et seq.); (b) The Safety and Health Regulations for Ship Repairing (29 CFR part 1915... at (HSAR) 48 CFR 3017.9000(a) and (b), insert the following clause: Department of Labor Safety and... and health regulations for ship repairing (USCG). 3052.217-99 Section 3052.217-99 Federal...
50 CFR 453.06 - Additional Committee powers.
... ADMINISTRATION, DEPARTMENT OF COMMERCE); ENDANGERED SPECIES COMMITTEE REGULATIONS ENDANGERED SPECIES EXEMPTION PROCESS ENDANGERED SPECIES COMMITTEE § 453.06 Additional Committee powers. (a) Secure information....
7 CFR 1944.686 - Additional grants.
... 7 Agriculture 13 2013-01-01 2013-01-01 false Additional grants. 1944.686 Section 1944.686 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED)...
7 CFR 1738.307 - Additional policies.
... 7 Agriculture 11 2013-01-01 2013-01-01 false Additional policies. 1738.307 Section 1738.307 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE RURAL BROADBAND ACCESS LOANS AND LOAN GUARANTEES Loan Guarantee § 1738.307 Additional...
Touchberry, Chad D.; Green, Troy M.; Tchikrizov, Vladimir; Mannix, Jaimee E.; Mao, Tiffany F.; Carney, Brandon W.; Girgis, Magdy; Vincent, Robert J.; Wetmore, Lori A.; Dawn, Buddhadeb; Bonewald, Lynda F.; Stubbs, Jason R.
Fibroblast growth factor 23 (FGF23) is a hormone released primarily by osteocytes that regulates phosphate and vitamin D metabolism. Recent observational studies in humans suggest that circulating FGF23 is independently associated with cardiac hypertrophy and increased mortality, but it is unknown whether FGF23 can directly alter cardiac function. We found that FGF23 significantly increased cardiomyocyte cell size in vitro, the expression of gene markers of cardiac hypertrophy, and total protein content of cardiac muscle. In addition, FGFR1 and FGFR3 mRNA were the most abundantly expressed FGF receptors in cardiomyocytes, and the coreceptor α-klotho was expressed at very low levels. We tested an animal model of chronic kidney disease (Col4a3−/− mice) that has elevated serum FGF23. We found elevations in common hypertrophy gene markers in Col4a3−/− hearts compared with wild type but did not observe changes in wall thickness or cell size by week 10. However, the Col4a3−/− hearts did show reduced fractional shortening (−17%) and ejection fraction (−11%). Acute exposure of primary cardiomyocytes to FGF23 resulted in elevated intracellular Ca2+ ([Ca2+]i; F/Fo + 86%) which was blocked by verapamil pretreatment. FGF23 also increased ventricular muscle strip contractility (67%), which was inhibited by FGF receptor antagonism. We hypothesize that although FGF23 can acutely increase [Ca2+]i, chronically this may lead to decreases in contractile function or stimulate cardiac hypertrophy, as observed with other stress hormones. In conclusion, FGF23 is a novel bone/heart endocrine factor and may be an important mediator of cardiac Ca2+ regulation and contractile function during chronic kidney disease. PMID:23443925
Nonas, Cathy; Silver, Lynn D; Kettel Khan, Laura
In 2006, the New York City Department of Health and Mental Hygiene, seeking to address the epidemic of childhood obesity, issued new regulations on beverages, physical activity, and screen time in group child care centers. An evaluation was conducted to identify characteristics of New York City child care centers that have implemented these regulations and to examine how varying degrees of implementation affected children's behaviors. This article discusses results of this evaluation and how findings can be useful for other public health agencies. Knowing the characteristics of centers that are more likely to comply can help other jurisdictions identify centers that may need additional support and training. Results indicated that compliance may improve when rules established by governing agencies, national standards, and local regulatory bodies are complementary or additive. Therefore, the establishment of clear standards for obesity prevention for child care providers can be a significant public health achievement. PMID:25321629
... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.686 Additional grants. An additional HPG grant may be made when the grantee has achieved or nearly achieved the goals established...
Tárrega, Salomé; Castro-Carreras, Laia; Fernández-Aranda, Fernando; Granero, Roser; Giner-Bartolomé, Cristina; Aymamí, Neus; Gómez-Peña, Mónica; Santamaría, Juan J.; Forcano, Laura; Steward, Trevor; Menchón, José M.; Jiménez-Murcia, Susana
Background: Gambling disorder (GD) is characterized by a significant lack of self-control and is associated with impulsivity-related personality traits. It is also linked to deficits in emotional regulation and frequently co-occurs with anxiety and depression symptoms. There is also evidence that emotional dysregulation may play a mediatory role between GD and psychopathological symptomatology. Few studies have reported the outcomes of psychological interventions that specifically address these underlying processes. Objectives: To assess the utility of the Playmancer platform, a serious video game, as an additional therapy tool in a CBT intervention for GD, and to estimate pre-post changes in measures of impulsivity, anger expression and psychopathological symptomatology. Method: The sample comprised a single group of 16 male treatment-seeking individuals with severe GD diagnosis. Therapy intervention consisted of 16 group weekly CBT sessions and, concurrently, 10 additional weekly sessions of a serious video game. Pre-post treatment scores on South Oaks Gambling Screen (SOGS), Barratt Impulsiveness Scale (BIS-11), I7 Impulsiveness Questionnaire (I7), State-Trait Anger Expression Inventory 2 (STAXI-2), Symptom Checklist-Revised (SCL-90-R), State-Trait Anxiety Inventory (STAI-S-T), and Novelty Seeking from the Temperament and Character Inventory-Revised (TCI-R) were compared. Results: After the intervention, significant changes were observed in several measures of impulsivity, anger expression and other psychopathological symptoms. Dropout and relapse rates during treatment were similar to those described in the literature for CBT. Conclusion: Complementing CBT interventions for GD with a specific therapy approach like a serious video game might be helpful in addressing certain underlying factors which are usually difficult to change, including impulsivity and anger expression. PMID:26617550
5 CFR 7501.106 - Additional rules for certain Department employees involved in the regulation or oversight of...
... confidential financial disclosure report under 5 CFR part 2634 in: (i) The Office of the HUD Secretary, with... compliance with the principles set forth in 5 CFR 2635.403 and who receives notice of such designation. (2... disqualification, or take other appropriate action determined to be necessary consistent with 5 CFR part 2635...
Demands for Testimony or Records in Legal Proceedings. Final Regulations. Federal Register, Department of Education 34 CFR Part 8
The Secretary amends the regulations regarding the production of information pursuant to demands in judicial or administrative proceedings. The changes are intended to promote consistency in the Department's assertion of privileges and objections, and thereby prevent harm that may result from inappropriate disclosure of confidential information or…
The addition of red lead to flat plate and tubular valve regulated miners cap lamp lead-acid batteries
Ferg, E. E.; Loyson, P.; Poorun, A.
The study looked at the use of red lead in the manufacturing of valve regulated lead acid (VRLA) miners cap lamp (MCL) batteries that were made with either flat plate or tubular positive electrodes. A problem with using only grey oxide in the manufacture of thick flat plate or tubular electrodes is the poor conversion of the active material to the desired lead dioxide. The addition of red lead to the initial starting material improves the formation efficiency but is considerably more expensive thereby increasing the cost of manufacturing. The study showed that by carefully controlling the formation conditions in terms of the voltage and temperature of a battery, good capacity performance can be achieved for cells made with flat plate electrodes that contain up to 25% red lead. The small amount of red lead in the active cured material reduces the effect of electrode surface sulphate formation and allows the battery to achieve its rated capacity within the first few cycles. Batteries made with flat plate positive electrodes that contained more that 50% red lead showed good initial capacity but had poor structural active material bonding. The study showed that MCL batteries made with tubular positive electrodes that contained less than 75% red lead resulted in a poorly formed electrode with limited capacity utilization. Pickling and soaking times of the tubular electrodes should be kept at a minimum thereby allowing higher active material utilization during subsequent capacity cycling. The study further showed that it is beneficial to use higher formation rates in order to reduce manufacturing time and to improve the active material characteristics.
Innovation for Teacher Quality. Final Regulations. Federal Register, Department of Education, 34 CFR Part 230
The Secretary issues regulations prescribing criteria to be used in selecting eligible members of the Armed Forces to participate in the Troops-to-Teachers program and receive financial assistance. These regulations implement section 2303(c) of the Elementary and Secondary Education Act of 1965, as amended (Act). The regulations also define the…
Magnet Schools Assistance Program. Final Regulations. Federal Register, Department of Education, 34 CFR Part 280
The Secretary amends the Magnet Schools Assistance Program (MSAP) regulations to reflect changes made to the Elementary and Secondary Education Act of 1965 (ESEA), as amended by the No Child Left Behind Act of 2001 (NCLB). These regulations are effective March 3, 2004. [These final regulations were prepared by the Office of Innovation and…
48 CFR 970.1100-2 - Additional considerations.
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Additional considerations. 970.1100-2 Section 970.1100-2 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Describing Agency Needs 970.1100-2 Additional considerations. (a) While it is...
... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Additional requirements for major systems. 207.106 Section 207.106 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING ACQUISITION PLANNING Acquisition Plans 207.106 Additional requirements for...
77 FR 40302 - Department of the Treasury Acquisition Regulation; Internet Payment Platform
.... Eastern Time. On February 23, 2012 (77 FR 10714) the Department published a proposed rule that would add a.... The Department published a correction to the proposed rule on March 5, 2012 (77 FR 13069). The... requires a computer and Internet access, which all entities that seek to contract with the...
Regulating Behavioral Procedures for Individuals with Handicaps: Review of State Department Standards.
Morgan, Robert L.; And Others
This study analyzed and compared the behavioral procedure standards of 39 state departments of special education and 41 state departments of developmental disabilities/mental retardation. Results are discussed in terms of systematic monitoring of procedures, staff training, procedures to increase behavior, prohibiting/restricting procedure use,…
75 FR 9107 - Regulation of Fuels and Fuel Additives: Federal Volatility Control Program in the Denver-Boulder...
... (58 FR 51735, October 4, 1993) and therefore is not subject to review under the EO. The Colorado... existing regulations, the phase I and phase 2 volatility rules (55 FR 11868, March 22, 1989 and 55 FR 23658... implications, as specified in Executive Order 13175 (65 FR 67249, November 9, 2000). This final rule...
76 FR 15855 - Denial of Petitions for Reconsideration of Regulation of Fuels and Fuel Additives: Changes to...
... Administrator to reconsider an EPA rule, published on March 26, 2010 (75 FR 14670), which amended the Renewable... Administrator to reconsider an EPA rule, published on March 26, 2010 (75 FR 14670), which amended the Renewable... AGENCY 40 CFR Part 80 Denial of Petitions for Reconsideration of Regulation of Fuels and Fuel...
Environmentally Realistic Mixtures of the Five Regulated Haloacetic Acids Exhibit Concentration-Dependent Departures from Dose Additivity
Disinfection of water decreases waterborne disease. Disinfection byproducts (DBPs) are formed by the reaction of oxidizing disinfectants with inorganic and organic materials in the source water. The U.S. EPA regulates five haloacetic acid (HAA) DBPs as a mixture. The objective ...
7 CFR 301.76-6 - Additional conditions for issuance of certificates and limited permits for regulated articles...
... interstate movement of any regulated article to any State if: (1) The article is treated with methyl bromide 3 in accordance with 7 CFR part 305 of this chapter. 3 EPA and State and local environmental authorities may restrict the use of methyl bromide on certain articles. (2) The article is shipped in...
76 FR 30264 - Department of State Acquisition Regulation; Foreign Nationals and Third Country Nationals
....gov SUPPLEMENTARY INFORMATION: The Department published a proposed rule, Public Notice 5684 at 72 FR..., productivity, innovation, or on the ability of United States-based companies to compete with foreign...
Kamada-Nobusada, Tomoe; Makita, Nobue; Kojima, Mikiko; Sakakibara, Hitoshi
Cytokinin activity in plants is closely related to nitrogen availability, and an Arabidopsis gene for adenosine phosphate-isopentenyltransferase (IPT), IPT3, is regulated by inorganic nitrogen sources in a nitrate-specific manner. In this study, we have identified another regulatory system of cytokinin de novo biosynthesis in response to nitrogen status. In rice, OsIPT4, OsIPT5, OsIPT7 and OsIPT8 were up-regulated in response to exogenously applied nitrate and ammonium, with accompanying accumulation of cytokinins. Pre-treatment of roots with l-methionine sulfoximine, a potent inhibitor of glutamine synthetase, abolished the nitrate- and ammonium-dependent induction of OsIPT4 and OsIPT5, while glutamine application induced their expression. Thus, neither nitrate nor ammonium, but glutamine or a related metabolite, is essential for the induction of these IPT genes in rice. On the other hand, glutamine-dependent induction of IPT3 occurs in Arabidopsis, at least to some extent. In transgenic lines repressing the expression of OsIPT4, which is the dominant IPT in rice roots, the nitrogen-dependent increase of cytokinin in the xylem sap was significantly reduced, and seedling shoot growth was retarded despite sufficient nitrogen. We conclude that plants possess multiple regulation systems for nitrogen-dependent cytokinin biosynthesis to modulate growth in response to nitrogen availability. PMID:24058148
... and Asian Citrus Psyllid § 301.76-7 Additional conditions for issuance of certificates and limited... area if: (1) The nursery stock is treated for Asian citrus psyllid with an APHIS-approved soil drench... § 301.76-6(b)(1), or with methyl bromide or irradiation, in accordance with 7 CFR part 305 of...
Gene expression suggests conserved aspects of Hox gene regulation in arthropods and provides additional support for monophyletic Myriapoda.
Janssen, Ralf; Budd, Graham E
Antisense transcripts of Ultrabithorax (aUbx) in the millipede Glomeris and the centipede Lithobius are expressed in patterns complementary to that of the Ubx sense transcripts. A similar complementary expression pattern has been described for non-coding RNAs (ncRNAs) of the bithoraxoid (bxd) locus in Drosophila, in which the transcription of bxd ncRNAs represses Ubx via transcriptional interference. We discuss our findings in the context of possibly conserved mechanisms of Ubx regulation in myriapods and the fly.Bicistronic transcription of Ubx and Antennapedia (Antp) has been reported previously for a myriapod and a number of crustaceans. In this paper, we show that Ubx/Antp bicistronic transcripts also occur in Glomeris and an onychophoran, suggesting further conserved mechanisms of Hox gene regulation in arthropods.Myriapod monophyly is supported by the expression of aUbx in all investigated myriapods, whereas in other arthropod classes, including the Onychophora, aUbx is not expressed. Of the two splice variants of Ubx/Antp only one could be isolated from myriapods, representing a possible further synapomorphy of the Myriapoda. PMID:20849647
77 FR 14854 - 30-Day Notice of Proposed Information Collection: Department of State Acquisition Regulation...
... receive Department of State contracts. Estimated Number of Respondents: 3,466. Estimated Number of Responses: 9,316. Average Hours Per Response: Varies. Total Estimated Burden: 275,970 hours. Frequency: On... collection is necessary to properly perform our functions. Evaluate the accuracy of our estimate of...
... FAMILIES, CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT PROGRAM CHILD ABUSE AND NEGLECT PREVENTION AND... regulations are applicable to all grants made under this part: 45 CFR Part 16—Procedures of the Departmental Grant Appeals Board. 45 CFR Part 46—Protection of human subjects 45 CFR Part 74—Administration of...
The Secretary amends the regulations governing the Magnet Schools Assistance Program (MSAP) in 34 CFR part 280. These amendments allow the MSAP to use an approach similar to that in section 75.200 for establishing selection criteria in grant competitions. Under this approach the MSAP has the flexibility to use selection criteria from its program…
Direct Grant Programs. Final Regulations. Federal Register, Department of Education, 34 CFR Part 75
The Secretary amends regulations governing the process for submitting discretionary grant applications by removing current provisions requiring specific application formats, thereby permitting electronic submission of applications. The revisions also clarify that only applicants submitting paper applications are required to submit one original and…
Scoditti, Egeria; Massaro, Marika; Carluccio, Maria Annunziata; Pellegrino, Mariangela; Wabitsch, Martin; Calabriso, Nadia; Storelli, Carlo; De Caterina, Raffaele
Adiponectin, an adipocyte-derived insulin-sensitizing and anti-inflammatory hormone, is suppressed in obesity through mechanisms involving chronic inflammation and oxidative stress. Olive oil consumption is associated with beneficial cardiometabolic actions, with possible contributions from the antioxidant phenol hydroxytyrosol (HT) and the monounsaturated fatty acid oleic acid (OA, 18:1n-9 cis), both possessing anti-inflammatory and vasculo-protective properties. We determined the effects of HT and OA, alone and in combination, on adiponectin expression in human and murine adipocytes under pro-inflammatory conditions induced by the cytokine tumor necrosis factor(TNF)-α. We used human Simpson-Golabi-Behmel syndrome (SGBS) adipocytes and murine 3T3-L1 adipocytes as cell model systems, and pretreated them with 1-100 μmol/L OA, 0.1-20 μmol/L HT or OA plus HT combination before stimulation with 10 ng/mL TNF-α. OA or HT significantly (P<0.05) prevented TNF-α-induced suppression of total adiponectin secretion (by 42% compared with TNF-α alone) as well as mRNA levels (by 30% compared with TNF-α alone). HT and OA also prevented-by 35%-TNF-α-induced downregulation of peroxisome proliferator-activated receptor PPARγ. Co-treatment with HT and OA restored adiponectin and PPARγ expression in an additive manner compared with single treatments. Exploring the activation of JNK, which is crucial for both adiponectin and PPARγ suppression by TNF-α, we found that HT and OA additively attenuated TNF-α-stimulated JNK phosphorylation (up to 55% inhibition). In conclusion, the virgin olive oil components OA and HT, at nutritionally relevant concentrations, have additive effects in preventing adiponectin downregulation in inflamed adipocytes through an attenuation of JNK-mediated PPARγ suppression. PMID:26030149
The use of nanometer tetrabasic lead sulfate as positive active material additive for valve regulated lead-acid battery
Lang, Xiaoshi; Wang, Dianlong; Hu, Chiyu; Tang, Shenzhi; Zhu, Junsheng; Guo, Chenfeng
Conventional tetrabasic lead sulfate used as positive active material additive shows the results of the low effective lead dioxide conversion rate due to the large grain size and crossed the crystal structure. In this paper, we study on a type of nanometer tetrabasic lead sulfate. Through the XRD and SEM test and Material Studio software calculation, the purity of tetrabasic lead sulfate is very high, the grain size of the nanometer 4BS is almost unanimous, and can be controlled below 200 nm. When charged and discharged in 1.75 V-2.42 V with the current density of 40 mA g-1, 80 mA g-1 and 160 mA g-1, the effective lead dioxide conversion rate of nanometer 4BS after formation can achieve to 83.48%, 71.42%, and 66.96%. Subsequently, the nanometer 4BS as additive is added to positive paste of lead-acid battery. When the batteries are tested galvanostatically between 1.75 V and 2.42 V at 0.25 C charge and 0.5 C discharge rates at room temperature. The ratio of adding nanometer 4BS is 0%, 1% and 4% and the initial discharge specific capacities are 60 mAh g-1, 65 mAh g-1 and 68 mAh g-1. After 80 cycles, the initial discharge capacity of positive active material with 1% nanometer 4BS decreased less than 10%, while adding 4% nanometer 4BS, the initial discharge capacity doesn't decrease obviously.
48 CFR 1452.236-71 - Additive or Deductive Items.
... Items. 1452.236-71 Section 1452.236-71 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Additive or Deductive Items. As prescribed in 1436.571, insert the following provision: Additive or Deductive Items—Department of the Interior (JUL 1996) So that the Government may obtain the most...
48 CFR 218.170 - Additional acquisition flexibilities.
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Additional acquisition flexibilities. 218.170 Section 218.170 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES EMERGENCY ACQUISITIONS Available Acquisition Flexibilities...
49 CFR 389.25 - Additional rule making proceedings.
... 389.25 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS RULEMAKING PROCEDURES-FEDERAL MOTOR CARRIER SAFETY REGULATIONS Procedures for Adoption of Rules § 389.25 Additional...
48 CFR 1406.303-70 - Additional requirements.
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Additional requirements. 1406.303-70 Section 1406.303-70 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 1406.303-70 Additional requirements. (a) If other...
Addition of crude glycerin to pig diets: sow and litter performance, and metabolic and feed intake regulating hormones.
Hernández, F; Orengo, J; Villodre, C; Martínez, S; López, M J; Madrid, J
The continued growth in biofuel production has led to a search for alternative value-added applications of its main by-product, crude glycerin. The surplus glycerin production and a higher cost of feedstuffs have increased the emphasis on evaluating its nutritive value for animal feeding. The aim of this research was to evaluate the effect of the dietary addition of crude glycerin on sow and litter performance, and to determine the serum concentrations of hormones related to energy metabolism and feed intake in sows during gestation and lactation. A total of 63 sows were assigned randomly to one of three dietary treatments, containing 0, 3 or 6% crude glycerin (G0, G3 and G6, respectively) added to a barley-soybean meal-based diet. During gestation, none of the dietary treatments had an effect on performance, while during lactation, glycerin-fed sows consumed less feed than those fed the control diet (3.8 v. 4.2kg DM/day; P=0.007). Although lactating sows fed the G3 diet had a higher BW loss than those fed the control diet (���20.6 v. ���8.7 kg; P=0.002), this difference was not reflected in litter performance. In gestation, the inclusion of glycerin did not affect blood concentrations of insulin or cortisol. However, pregnant sows fed diets supplemented with glycerin showed lower concentrations of acyl-ghrelin and higher concentrations of leptin (���55 and +68%, respectively; P<0.001). In lactating sows, there were no differences between dietary treatments for any of the hormones measured. Pre-prandial acyl-ghrelin concentrations were positively correlated with cortisol concentrations during gestation (r=0.81; P=0.001) and lactation (r=0.61; P=0.015). In conclusion, the inclusion of up to 6% crude glycerin did not affect the performance of sows during the gestation period; however it had a negative effect on the feed intake and weight loss of lactating sows. Moreover, further research is needed to elucidate the potential relationship between
Project UPGRADE: Model Regulations for School Language, Speech, and Hearing Programs and Services. Phase I: Recommendations for State Departments of Education in Implementing Comprehensive Regulations for Language, Speech and Hearing Services in the Schools.
American Speech and Hearing Association, Washington, DC.
The document presents a legally formulated set of model regulations for state education departments to be used in accordance with law in support of quality in comprehensive school language, speech, and hearing programs. Nine sections cover regulations in the following areas: (l) authority, scope, general principles, effect, and definitions; (2)…
Graphite and fiberglass additives for improving high-rate partial-state-of-charge cycle life of valve-regulated lead-acid batteries
Valenciano, J.; Sánchez, A.; Trinidad, F.; Hollenkamp, A. F.
In order to accommodate regenerative braking energy input in hybrid and mild hybrid vehicles while maintaining boosting power at high rates of discharge, valve-regulated lead-acid (VRLA) batteries must operate permanently at partial-state-of-charge (PSoC) conditions. As a consequence, new failure modes appear, e.g., irreversible sulfation in negative plates, that have to be overcome. In this way, work has been done to apply some solutions like improving charge acceptance in this "sulfated medium". Several batches of 6 V 20 Ah AGM VRLA batteries with spiral cell design have been assembled and tested, each batch containing novel additives in the negative active material (NAM). It has been observed that the addition of a sufficient amount of expanded graphite significantly improves cycle life under PSoC conditions. Moreover, life duration is also extended, although to a lesser extent, by using a novel fiberglass which increases surface area of NAM.
... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Additional considerations. 990.66 Section 990.66 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OIL POLLUTION ACT...
15 CFR 292.6 - Additional requirements.
... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Additional requirements. 292.6 Section 292.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS MANUFACTURING...
... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Additional requirements. 292.6 Section 292.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS MANUFACTURING...
... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Additional requirements. 292.6 Section 292.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS MANUFACTURING...
... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Additional requirements. 292.6 Section 292.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS MANUFACTURING...
... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Additional requirements. 292.6 Section 292.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS MANUFACTURING...
... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Additional considerations. 990.66 Section 990.66 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OIL POLLUTION ACT...
34 CFR 300.308 - Additional group members.
... 34 Education 2 2011-07-01 2010-07-01 true Additional group members. 300.308 Section 300.308 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF CHILDREN WITH DISABILITIES Evaluations,...
... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Additional Committee powers. 453.06 Section 453.06 Wildlife and Fisheries JOINT REGULATIONS (UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR AND NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE); ENDANGERED...
Department of Education Organization Act of 1978. Report of the Committee on Governmental Affairs, United States Senate, to Accompany S.991 to Establish a Department of Education and for Other Purposes, Together with Additional Views.
This report explains, evaluates, and recommends the passage of Senate Bill 991 establishing a Federal Department of Education. The purpose and history of the legislation are presented along with the reasons for establishing a Department of Education and a summary of the legislation and hearings. Areas of discussion included are citizen…
49 CFR 172.203 - Additional description requirements.
... 49 Transportation 2 2011-10-01 2011-10-01 false Additional description requirements. 172.203 Section 172.203 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS HAZARDOUS MATERIALS TABLE, SPECIAL PROVISIONS,...
... 29 Labor 3 2012-07-01 2012-07-01 false Excluding certain additions to wages. 548.305 Section 548.305 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS AUTHORIZATION OF ESTABLISHED BASIC RATES FOR COMPUTING OVERTIME PAY Interpretations Authorized Basic Rates § 548.305 Excluding...
... 29 Labor 3 2013-07-01 2013-07-01 false Excluding certain additions to wages. 548.305 Section 548.305 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS AUTHORIZATION OF ESTABLISHED BASIC RATES FOR COMPUTING OVERTIME PAY Interpretations Authorized Basic Rates § 548.305 Excluding...
... 29 Labor 3 2014-07-01 2014-07-01 false Excluding certain additions to wages. 548.305 Section 548.305 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS AUTHORIZATION OF ESTABLISHED BASIC RATES FOR COMPUTING OVERTIME PAY Interpretations Authorized Basic Rates § 548.305 Excluding...
... 29 Labor 3 2010-07-01 2010-07-01 false Excluding certain additions to wages. 548.305 Section 548.305 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS AUTHORIZATION OF ESTABLISHED BASIC RATES FOR COMPUTING OVERTIME PAY Interpretations Authorized Basic Rates § 548.305 Excluding...