Source: http://grants1.nih.gov/grants/guide/rfa-files/RFA-RR-11-001.html
Timestamp: 2014-07-22 20:13:51
Document Index: 16757717

Matched Legal Cases: ['art%207', 'art 7', 'art%207', 'art 100', 'art 52', 'arts 74']

RFA-RR-11-001: Limited Competition: Extramural Research Facilities Improvement Program (C06)
Office of AIDS Research (OAR) http://www.oar.nih.gov/ Funding Opportunity Title
Limited Competition: Extramural Research Facilities
Improvement Program (C06) Activity Code
February 21, 2013 - This RFA has been reissued as RFA-OD-13-003.
RFA-RR-11-001
defined in Section III. 3. Section III.
3. Additional Information on Eligibility. Catalog of Federal Domestics Assistance (CFDA) Number(s) 93.389
This FOA solicits applications from National Primate
Research Centers (NPRCs) that propose to expand, remodel, renovate, or alter
biomedical or behavioral research facilities. The proposed facilities must
be used to support the development of appropriate experimental research and
housing facilities to conduct HIV/AIDS related research with non-human
primates (NHPs).
December 27, 2010 Letter of Intent Due Date
February 4, 2011, by 5:00 PM local time of applicant
Not applicable Scientific Merit Review May/June 2011 Advisory Council Review
September 2011 Earliest Start Date(s)
Due Dates for E.O. 12372 February 4, 2011
This FOA requests applications on the construction, expansion,
repair or renovation of new or existing research facilities at the NPRCs. The availability of improved facilities will speed the translation of basic
research to treatments and cures. The proposed construction project must
support the development of appropriate experimental research and housing
facilities to conduct HIV/AIDS related research with non-human primates (NHP). Applicants can propose major alterations and renovations (A&R) to
existing facilities, add to existing facilities, complete uninhabitable shell
space in existing facilities, or construct new facilities. Competition is
limited to the National Primate Research Centers (http://www.ncrr.nih.gov/comparative_medicine/resource_directory/primates.asp). Funds requested can range from $500,000 to $1.5M. The institution is not
required to provide matching funds. The acquisition and installation of fixed equipment such as
biological safety cabinets are allowed. Discussion of the appropriateness of
the location of such instruments should be part of the application. The
location of all fixed equipment should be noted in the line drawings.
A list of appropriate equipment can be found at http://ncrr.nih.gov/research_funding/instruments/ . If you plan to request equipment that is not on this list, you should
discuss this issue with program staff before submitting your application. Applications
must not request only fixed equipment when responding to this FOA. Applications that request only fixed equipment and do not have any renovation
component will be returned as non-responsive.
No facilities and administrative (F&A) costs or
continuation costs will be awarded. The NIH reserves the right to conduct
post award site visits when deemed essential.
Special notes for Magnetic Resonance Imaging Facilities (MRI):
The planning, design, and installation of a MRI system in a facility requires
extreme care to ensure that the magnet is sufficiently isolated from
ferromagnetic and radio frequency influences of the impacted environment and
must be followed. Consultants should be used to verify specific requirements. Discussion of the appropriateness of the location of such instruments as well
as all requested fixed equipment should be part of the application. It is expected that green/sustainable technologies and
design approaches will be employed when possible. When preparing an
application, the impact of the improvements or the equipment on the environment
must be considered and described in the application. Applicants
are encouraged to implement the following listed primary elements of sustainable
design in federally-funded facilities. Sustainability is the outcome of
an integrated process of facility development and operation incorporating a
balance of life-cycle cost, environmental impact, and occupant health and
safety, security, and productivity. At minimum, the following primary elements
of sustainable design are expected to be included in all projects.
3. Optimization of
6. Protection and
6.a. Indoor water (i.e., fixtures that reduce
amount of water used; recycling of waste water)
6.b. Outdoor water (i.e., natural site drainage
and low impact storm water retention)
7. Enhancement of indoor
12. Protection of indoor air quality
13. Reducing the environmental
impact of materials.
14. Maximizing recycled and
15. Construction waste reuse and
16. Minimizing use of ozone
depleting compounds.
certification, during the design phase, from the U.S. Green Building Council’s
Leadership in Energy and Environmental Design (LEED) or the Green Building
initiative’s Green Globes System Certification rating system.
Green/Sustainable Design References Department of Health and Human Services. HHS Policy for
Sustainable and High Performance Buildings. December 2007. http://www.hhs.gov/asam/ofmp/hiperfbldngpol.pdf Department of Health and Human Services. HHS Real Property
Asset Management Plan. http://www.hhs.gov/asam/ofmp/ramp.doc Executive Order 13101: Greening the Government through Waste
Prevention, Recycling, and Federal Acquisition. http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=1998_register&docid=fr16se98-113.pdf Executive Order 13123: Greening the Government through
Efficient Energy Management. http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=1999_register&docid=fr08jn99-171.pdf Executive Order 13134: Developing and Promoting Biobased
Products and Bioenergy. http://www.archives.gov/federal-register/executive-orders/1999.html#13134 Executive Order 13148: Greening the Government through
Leadership in Environmental Management. http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=2000_register&docid=fr26ap00-129.pdf OMB Circular A-11, Section 55-Energy and Transportation
Efficiency Management. http://www.whitehouse.gov/omb/circulars/a11/current_year/s300.pdf#search=%22OMB%20Circular%20A-11%20Part%207%22 OMB Circular A-11, Part 7 (Section 300), Planning,
Budgeting, Acquisition, and Management of Capital Assets. http://www.whitehouse.gov/omb/circulars/a11/current_year/s300.pdf#search=%22OMB%20Circular%20A-11%20Part%207%22 The Federal Leadership in High Performance and Sustainable
Buildings, Memorandum of Understanding. http://www.energystar.gov/ia/business/Guiding_Principles.pdf Green Building Initiative Green Globes System. http://www.thegbi.org US Green Building Council. http://www.usgbc.org Whole Building Design Guide http://www.wbdg.org
Funds Available and Anticipated Number of Awards The participating NIH IC components intend to commit $5M,
for 3-5 awardsin FY 2011. Award Budget
Application budgets are limited to $500,000 to $1.5M, and
need to reflect actual needs of proposed project. Award Project Period
Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education Nonprofits Other Than Institutions of Higher Education
Comment: For Profit Organizations are not allowed Required Registrations
Person Profile (Expanded) Component of the SF 424 (R&R) Application Guide. The PD/PI must be a highly placed institutional individual
who has responsibility for allocation of space for biomedical and behavioral
research and research training, e.g. Dean, Provost, Department Head, Center or
Institute Director. Individuals from underrepresented racial and ethnic
for NIH support. Only one PD/PI may be designated on the application. 2. Cost Sharing
application that is essentially the same as one already reviewed. Only one application per institution
(normally identified by having a unique DUNS number or NIH IPF number) is
requirements: Research Plan is limited to 12 pages. PHS 398 Research Plan Component
must be followed, with the following additional instructions: All attachments must be provided to NIH in PDF format,
extension must be used. The Program Narrative should include the following sections
and should be submitted in a single PDF attachment. The Program Narrative is
limited to a total of 12 pages and should be included on the “Other Project
Information” form.
Aims: This section must be one page or less. The
Specific Aims should (1) summarize any request for improvement including the
associated square footage and (2) list all requested equipment. Background: The Background and Significance section must not exceed one page. This
section should briefly describe the background leading to the present
application. State concisely the importance of this improvement project
to the performance of HIV/AIDS related research using non-human primates at the
institution. The rest of the application can be up to 10 pages (or
more) as long as the number of pages in the Specific Aims, Background, and
Improvement Plans sections totals no more than 12 pages. The page limits
in this section do NOT include the requested tables or line drawings. The
application should include the following sections.
and Need: Begin with two tables containing (1) active
columns: grant title, principal investigator, grant number, funding
source, annual amount of funding, start and end dates. These tables do
not count toward the page limits.
describe how the new facilities will expand, improve, or maintain existing research
and research support activities. Future scientific needs that would be
accommodated as part of the new facility also should be described.
Management and Institutional Commitment: Describe the
administrative structure and oversight for the project. Describe the role
of the Project Manager. Describe the ongoing institutional commitment to the
new or altered space.
Considerations: List in tabular format the size (dimensions)
etc.) that will be directly affected by the improvement project.
Criteria: Provide information about the mechanical,
electrical, plumbing systems and utilities in each component. Include
information about the number of air changes per hour; electrical power; light
levels; hot and cold water; steam; mechanical, electrical, and plumbing (MEP)
requirements; fire protection requirements; biohazard and radiation safety
requirements; chemicals used; major scientific equipment to be installed
including environmental rooms; density of fume hoods; building population; and the
number of workstations, security/surveillance and building automation systems.
Criteria: Provide architectural criteria such as the width of
corridors and doors and surface finishes. Architectural criteria should
also address quality of life issues (e.g. natural lighting, noise, vibration),
a planning module (laboratory neighborhood concepts, central support core
concepts, material management), and planning concepts and functional
relationships and zoning of the area to be improved. Sufficient
information must be provided to allow the evaluation of plans for Biological
Safety Level-3/Animal Biological Safety Level-3 (BSL-3/ABSL-3) designs, animal
facility designs, and designs for clinical facilities.
Drawings: Include floor plans for the improvement. The
line drawings must fit on an 8.5” x 11” sheet of paper. Do not submit
blueprints. All floor plans must be legible with the scale clearly
indicated. The floor plans must indicate the location of equipment and
illustrate safety clearances and workspace. If applicable, submit both
existing and proposed drawings. The drawings should indicate size
dimensions, function, and the net and gross square feet for each room. The total net and gross square feet of space to be improved should also be
given. The plan should indicate the location of the proposed
construction/renovation area in the existing building. Changes or additions
to existing MEP systems should be clearly described in notes made directly on
the plan or attached to the plan. The line drawings must indicate egress
routes. The drawings must indicate the functional layout of the proposed
facility showing the location of entries and exits, clearances, and the
location of fixed equipment. The line drawings do not count toward the
page limits. Additional text must not be included in the line drawings to
circumvent the page limits. Such additional text will be counted toward the 12
page limit of the “Project Narative.” Equipment: List and justify all fixed equipment. Equipment should be relevant and
should serve an identified user group. Information such as the
facility should be included. The table of fixed equipment will not count
toward the 12 page limit of the Project Narrative. The justification for the
equipment should be presented in the Budget Justification section below. Project
Timeline: Show plans to complete the project within three
years following the approval of designs.
This FOA does not allow appendix
OTHER ATTACHMENTS In the Other Attachments section, include the following,
each as a separate attachment. NOTE: Each attachment must be given a file name
using the headings below (e.g., Environmental_Analysis_Form).
(1) Environmental Analysis Form (http://www.ncrr.nih.gov/resinfra/environmental_Analysis_Form.pdf. (2) Budget Justification and Vendor Quotes: The next
justification must be provided for each piece of equipment.
(3) Certification of Title to Site: Applicants must
(4) Documents associated with the Executive Order 12372, if
The following documents are likely to be useful when
NIH Grants Policy Statement 10/01/10) Part II- Subpart B
(construction grants) http://grants.nih.gov/grants/policy/nihgps_2010/nihgps_ch10.htm Please refer to this document for a representative list of allowable and
unallowable costs. Biosafety in Microbiological and Biomedical Laboratories,
Research Council, National Academy Press, Washington, D.C. http://www.nyu.edu/uawc/doc/guide-excerpts.pdf NIH Model Commissioning guide http://des.od.nih.gov/eWeb/research/farhad2/Commissioning/nih_cx_guide/ComGuideTitle.htm All application instructions outlined in the SF424 (R&R)
review. Applicants are required to comply with Executive Order (E.O.) 12372
as implemented by 45 CFR Part 100, Intergovernmental Review of Department of
Health and Human Services Programs and Activities. E.O. 12372 sets up a system
for state and local government review of proposed Federal assistance
applications. Applicants (other than federally recognized Indian tribal
governments) should contact their State Single Point of Contact (SPOC) as early
as possible to alert them to the prospective applications and receive any
necessary instructions on the state process. For proposed projects
serving more than one state, the applicant is advised to contact the SPOC of
each affected state. A current list of SPOCs is located at http://www.whitehouse.gov/omb/grants/spoc.html. States without a SPOC do not participate in this process. The SPOC must be
given 60 days to review a construction grant application. Applicants are
to provide the SPOC with a copy of the application not later than the time the
application is submitted to the Center for Scientific Review (CSR), NIH. Applications submitted to NIH in response to this solicitation must contain
either SPOC comments or documentation indicating the date on which the
application was submitted to the SPOC for review. The SPOC comment period
ends 60 days after the application receipt date. The granting agency does not
guarantee to accommodate or explain state process recommendations it receives
after that date. All SPOC comments must be forwarded to both the applicant
the comments and any appropriate changes in its application. If no
response is received from the SPOC by the end of the 60 days allotted for
review of the application, the applicant must notify the NIH that no response was
received. 5. Funding Restrictions
Policy Statement. All funds are restricted except for Project Design and
award. The incurrence of pre-award costs in anticipation of a competing or
completeness by the Center for Scientific Review and responsiveness by NCRR, NIH. Applications that are incomplete and/or nonresponsive will not be reviewed.
applicant to check periodically on the application status in the Commons after
the receipt of the application. Section V. Application Review
The C06 program supports efforts to make major A&R to existing buildings,
buildings, or construct new facilities including research and animal
facilities. The major objective is to facilitate and enhance the conduct of Public
Health Service (PHS)-supported biomedical and behavioral research by supporting
the costs of improving basic research, clinical research, and animal facilities
to meet the biomedical or behavioral research, research training, or research
support needs of an institution.
Is there sufficient justification for improving this
improve, or maintain HIV/AIDS research? Will the conduct of HIV/AIDS related
research be enhanced? Investigator(s) Are the PD/PIs, collaborators, and other researchers
Does the PD/PI have the appropriate experience and
budget? Innovation
methodologies, instrumentation, or interventions proposed? Does the design implement sustainable design
to reduce adverse impacts on the environment? Approach
benchmarks for success presented? Does the plan indicate the proposed project
area in the building, including associated room adjacencies, research space, traffic
patterns for the movement of people, animals, and materials (clean and dirty)
through the facility, and relative location of needed ancillary areas (e.g.,
changing rooms for animal facilities)? Is the total net and gross square
feet of space to be improved provided? Are the proposed timeline and
sequence of construction reasonable? Are changes or additions to existing MEP
systems clearly described and adequate to the project? Are
identified deficiencies or fill gaps in the facility? Engineering Criteria: Do the engineering
criteria include information about the MEP systems, and utilities in the
renovation? Are the number of air changes per hour, electrical power,
light levels, hot and cold water, and steam appropriate for the project? Architectural Criteria: Are the architectural
criteria such as the width of corridors and doors and surface finishes
appropriate for the project? Line Drawings: Is the function of the space
indicated? Do the line drawings indicate the size dimensions, function,
and net and gross square feet for each component? Are the line
drawings at a scale adequate to explain the project? Do the plans
indicate the changes to be made to the space? Are the line drawings drawn
to scale to indicate adjacencies and operational relationships of
equipment? Is the location of major equipment, fume hoods, sinks,
showers, and other major items indicated in the drawings? Are areas to be
demolished indicated? Environment
Is the institution committed to using the renovated
space for HIV/AIDS research? Does the institution have a history of adequate
support for this facility? Additional Review Criteria
Protections for Human Subjects Generally not applicable. Reviewers should bring any
Inclusion of Women, Minorities, and Children Generally not applicable. Reviewers should bring any
should bring any concerns to the attention of the Scientific Review Officer.
merit by (an) appropriate Scientific Review Group(s) convened by NCRR (assignments will be shown in the eRA Commons), in accordance with NIH peer
will: Receive a written critique.
Applications will be assigned to NCRR . Applications will compete for available funds with all other recommended applications submitted in response to this FOA . Following initial peer review, recommended applications
will receive a second level of review by the NCRR National Advisory Council . The following will be considered in making funding decisions: Scientific and technical merit of the proposed project as
Direct inquiries about scientific and programmatic issues to Willie D. McCullough, Ph.D.
Office of Construction Grants
Telephone: 301- 435-0766
Direct inquiries regarding engineering or architectural issues
Esmail Torkashvan, P.E. Office of Construction Grants
Barbara J. Nelson, Ph.D. Office of Review National Center for Research Resources (NCRR) Telephone: (301) 435-0806 Email: nelsonbj@mail.nih.gov
Office of Grants Management National Center for Research Resources (NCRR)
Telephone: 301- 435-0840
under Federal Regulations 42 CFR Part 52 and 45 CFR Parts 74 and 92 The National Center for Research Resources (NCRR) is
authorized under Sections 481A of the Public Health Services Act, as amended by
Sections 303 and 304 of Public Law (PL) 106-505, to make grants or contracts to
public and nonprofit private entities to expand, remodel, renovate, or alter
existing research and/or animal facilities. Any awards resulting from this FOA will not be subject to
the provisions of the Davis-Bacon Act (40 U.S.C. Secs 276a to 276a-7).