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Matched Legal Cases: ['art 2', 'art 2', 'art 2', 'art 2', 'Application No. 07799148', 'Application No. 09156661', 'Application No. 05806045', 'Application No. 05811851', 'Application No. 06847926', 'Application No. 0775925', 'Application No. 07798341', 'Application No. 07799148', 'Application No. 07868755', 'Application No. 09156661', 'Application No. 09167937', 'Application No. 09168202', 'Application No. 09168204', 'art 2', 'art 2', 'art 2', 'art 1', 'art 2', 'art 2']

Patent US8145317 - Methods for renal neuromodulation - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign in<nobr>Advanced Patent Search</nobr>PatentsMethods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion,...http://www.google.com/patents/US8145317?utm_source=gb-gplus-sharePatent US8145317 - Methods for renal neuromodulationAdvanced Patent SearchPublication numberUS8145317 B2Publication typeGrantApplication numberUS 11/368,577Publication dateMar 27, 2012Filing dateMar 6, 2006Priority dateApr 8, 2002Also published asUS20060276852, US20120130289Publication number11368577, 368577, US 8145317 B2, US 8145317B2, US-B2-8145317, US8145317 B2, US8145317B2InventorsDenise Demarais, Hanson Gifford, III, Mark Deem, Douglas Sutton, Howard R. Levin, Mark GelfandOriginal AssigneeArdian, Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (99), Non-Patent Citations (574), Referenced by (10), Classifications (25), Legal Events (3) External Links: USPTO, USPTO Assignment, EspacenetMethods for renal neuromodulationUS 8145317 B2Abstract Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.
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