Source: http://www.google.com/patents/US20070239265?ie=ISO-8859-1&dq=oakley+5,387,949
Timestamp: 2015-07-31 11:40:16
Document Index: 774443106

Matched Legal Cases: ['art 100', 'art 100', 'art 100', 'art 100', 'art 100', 'art 100', 'art 100']

Patent US20070239265 - Catheter Delivered Valve Having a Barrier to Provide an Enhanced Seal - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsA system for treating abnormalities of the right ventricular outflow tract includes a prosthetic valve device having a barrier material contacting at least a portion of the outer surface of the valve device. One embodiment of the invention includes a barrier member attached to the exterior surface of...http://www.google.com/patents/US20070239265?utm_source=gb-gplus-sharePatent US20070239265 - Catheter Delivered Valve Having a Barrier to Provide an Enhanced SealAdvanced Patent SearchPublication numberUS20070239265 A1Publication typeApplicationApplication numberUS 11/278,925Publication dateOct 11, 2007Filing dateApr 6, 2006Priority dateApr 6, 2006Also published asUS7524331Publication number11278925, 278925, US 2007/0239265 A1, US 2007/239265 A1, US 20070239265 A1, US 20070239265A1, US 2007239265 A1, US 2007239265A1, US-A1-20070239265, US-A1-2007239265, US2007/0239265A1, US2007/239265A1, US20070239265 A1, US20070239265A1, US2007239265 A1, US2007239265A1InventorsMatthew BirdsallOriginal AssigneeMedtronic Vascular, Inc.Export CitationBiBTeX, EndNote, RefManReferenced by (18), Classifications (19), Legal Events (3) External Links: USPTO, USPTO Assignment, EspacenetCatheter Delivered Valve Having a Barrier to Provide an Enhanced Seal
TECHNICAL FIELD This invention relates generally to medical devices for treating cardiac valve abnormalities, and particularly to a pulmonary valve replacement system and method of employing the same. BACKGROUND OF THE INVENTION Heart valves, such as the mitral, tricuspid, aortic and pulmonary valves, are sometimes damaged by disease or by aging, resulting in problems with the proper functioning of the valve. Heart valve problems generally take one of two forms: stenosis, in which a valve does not open completely or the opening is too small, resulting in restricted blood flow; or insufficiency, in which blood leaks backward across a valve when it should be closed. The pulmonary valve regulates blood flow between the right ventricle and the pulmonary artery, controlling blood flow between the heart and the lungs. Pulmonary valve stenosis is frequently due to a narrowing of the pulmonary valve or the pulmonary artery distal to the valve. This narrowing causes the right side of the heart to exert more pressure to provide sufficient flow to the lungs. Over time, the right ventricle enlarges, which leads to congestive heart failure (CHF). In severe cases, the CHF results in clinical symptoms including shortness of breath, fatigue, chest pain, fainting, heart murmur, and in babies, poor weight gain. Pulmonary valve stenosis most commonly results from a congenital defect, and is present at birth, but is also associated with rheumatic fever, endocarditis, and other conditions that cause damage to or scarring of the pulmonary valve. Valve replacement may be required in severe cases to restore cardiac function. Previously, valve repair or replacement required open-heart surgery with its attendant risks, expense, and extended recovery time. Open-heart surgery also requires cardiopulmonary bypass with risk of thrombosis, stroke, and infarction. More recently, flexible valve prostheses and various delivery devices have been developed so that replacement valves can be implanted transvenously using minimally invasive techniques. As a consequence, replacement of the pulmonary valve has become a treatment option for pulmonary valve stenosis. The most severe consequences of pulmonary valve stenosis occur in infants and young children when the condition results from a congenital defect. Frequently, the pulmonary valve must be replaced with a prosthetic valve when the child is young, usually less than five years of age. However, as the child grows, the valve can become too small to accommodate the blood flow to the lungs that is needed to meet the increasing energy demands of the growing child, and it may then need to be replaced with a larger valve. Alternatively, in a patient of any age, the implanted valve may fail to function properly due to calcium buildup and have to be replaced. In either case, repeated surgical or transvenous procedures are required. To address the need for pulmonary valve replacement, various implantable pulmonary valve prostheses, delivery devices and surgical techniques have been developed and are presently in use. One such prosthesis is a bioprosthetic, valved conduit comprising a glutaraldehyde treated bovine jugular vein containing a natural, trileaflet venous valve, and sinus. A similar device is composed of a porcine aortic valve sutured into the center of a woven fabric conduit. A common conduit used in valve replacement procedures is a homograft, which is a vessel harvested from a cadaver. Valve replacement using either of these devices requires thoracotomy and cardiopulmonary bypass. When the valve in the prostheses must be replaced, for the reasons described above or other reasons, an additional surgery is required. Because many patients undergo their first procedure at a very young age, they often undergo numerous procedures by the time they reach adulthood. These surgical replacement procedures are physically and emotionally taxing, and a number of patients choose to forgo further procedures after they are old enough to make their own medical decisions. Recently, implantable stented valves have been developed that can be delivered transvenously using a catheter-based delivery system. These stented valves comprise a collapsible valve attached to the interior of a tubular frame or stent. The valve can be any of the valve prostheses described above, or it can be any other suitable valve. In the case of valves in harvested vessels, the vessel can be of sufficient length to extend beyond both sides of the valve such that it extends to both ends of the valve support stent. The stented valves can also comprise a tubular portion or “stent graft” that can be attached to the interior or exterior of the stent to provide a generally tubular internal passage for the flow of blood when the leaflets are open. The graft can be separate from the valve and it can be made from any suitable biocompatible material including, but not limited to, fabric, a homograft, porcine vessels, bovine vessels, and equine vessels. The stent portion of the device can be reduced in diameter, mounted on a catheter, and advanced through the circulatory system of the patient. The stent portion can be either self-expanding or balloon expandable. In either case, the stented valve can be positioned at the delivery site, where the stent portion is expanded against the wall of a previously implanted prostheses or a native vessel to hold the valve firmly in place. One embodiment of a stented valve is disclosed in U.S. Pat. No. 5,957,949 titled “Percutaneous Placement Valve Stent” to Leonhardt, et al, the contents of which are incorporated herein by reference. Over time, implanted prosthetic conduits and valves are frequently subject to calcification, causing the affected conduit or valve to lose flexibility, become misshapen, and fail to function effectively. Furthermore, because they are long term implants, synthetic conduits sometimes undergo longitudinal stretching or fibrotic ingrowth of the tissue surrounding the conduit. In either case, the conduit can become so distorted that blood flow is impeded or the valve is misaligned, allowing blood to flow around the periphery of the valve. An additional drawback of using a stented valve is that the stents are often difficult to properly position within a conduit resulting in a misplaced valve. Additionally, stented valves may migrate along the conduit after implantation due to forces applied by the blood flow through the vessel. It would be desirable, therefore, to provide an implantable pulmonary valve that can readily be replaced, and that would overcome the limitations and disadvantages inherent in the devices described above. SUMMARY OF THE INVENTION It is an object of the present invention to provide a vascular valve replacement system having at least a delivery catheter and a replacement valve device disposed on the delivery catheter. The replacement valve device includes a prosthetic valve connected to a valve support region of an expandable support structure. The valve support region includes a plurality of protective struts disposed between a first stent region and a second stent region. The system and the prosthetic valve will be described herein as being used for replacing a pulmonary valve. The pulmonary valve is also known to those having skill in the art as the “pulmonic valve” and as used herein, those terms shall be considered to mean the same thing. Thus, one aspect of the present invention provides a system for treating abnormalities of the right ventricular outflow tract comprising a conduit, a catheter and a prosthetic valve device. The prosthetic valve device comprises a valve connected to a support structure and a barrier member contacting at least a portion of the outer surface of the support structure of the valve device. When the valve device is deployed from the catheter and situated within the conduit, the barrier material prevents blood flow between the inner wall of the conduit and the outer surface of the support structure of the valve device. Another aspect of the invention provides a pulmonary valve replacement system comprising a conduit, a prosthetic valve device and a barrier material. The valve device is positioned within the conduit and the barrier is deployed from a catheter. When the barrier material is placed between the conduit and the outer surface of the support structure of the valve device to prevent blood flow around the valve device. Another aspect of the invention provides a pulmonary valve replacement system comprising a conduit, and a prosthetic valve device having a barrier member disposed about at least a portion of the support structure of the valve device. When the valve device is positioned within the lumen of the conduit, the barrier member contacts the surface of the interior wall of the conduit and prevents blood flow around the valve device. Another aspect of the invention provides a method for replacing a pulmonary valve. The method comprises using a catheter to deliver a pulmonary valve device to a treatment site within a conduit. The pulmonary valve device includes a valve connected to a support structure and a barrier material disposed about at least a portion of the outer surface of the support structure. The method further comprises deploying the valve device from the catheter, positioning the valve device within the conduit and forming a barrier and thereby preventing blood flow around the support structure. The present invention is illustrated by the accompanying drawings of various embodiments and the detailed description given below. The drawings should not be taken to limit the invention to the specific embodiments, but are for explanation and understanding. The detailed description and drawings are merely illustrative of the invention rather than limiting, the scope of the invention being defined by the appended claims and equivalents thereof. The drawings are not to scale. The foregoing aspects and other attendant advantages of the present invention will become more readily appreciated by the detailed description taken in conjunction with the accompanying drawings.
DETAILED DESCRIPTION The invention will now be described by reference to the drawings wherein like numbers refer to like structures. Referring to the drawings, FIG. 1 is a schematic representation of the interior of human heart 100. Human heart 100 includes four valves that work in synchrony to control the flow of blood through the heart. Tricuspid valve 104, situated between right atrium 118 and right ventricle 116, and mitral valve 106, between left atrium 120 and left ventricle 114 facilitate filling of ventricles 116 and 114 on the right and left sides, respectively, of heart 100. Aortic valve 108 is situated at the junction between aorta 112 and left ventricle 114 and facilitates blood flow from heart 100, through aorta 112 to the peripheral circulation. Pulmonary valve 102 is situated at the junction of right ventricle 116 and pulmonary artery 110 and facilitates blood flow from heart 100 through the pulmonary artery 110 to the lungs for oxygenation. The four valves work by opening and closing in harmony with each other. During diastole, tricuspid valve 104 and mitral valve 106 open and allow blood flow into ventricles 114 and 116, and the pulmonic valve and aortic valve are closed. During systole, shown in FIG. 1, aortic valve 108 and pulmonary valve 102 open and allow blood flow from left ventricle 114, and right ventricle 116 into aorta 112 and pulmonary 110, respectively. The right ventricular outflow tract is the segment of pulmonary artery 110 that includes pulmonary valve 102 and extends to branch point 122, where pulmonary artery 110 forms left and right branches that carry blood to the left and right lungs respectively. A defective pulmonary valve or other abnormalities of the pulmonary artery that impede blood flow from the heart to the lungs sometimes require surgical repair or replacement of the right ventricular outflow tract with prosthetic conduit 202, as shown in FIG. 2A-C. Such conduits comprise tubular structures of biocompatible materials, with a hemocompatible interior surface. Examples of appropriate biocompatible materials include polytetrafluoroethylene (PTFE), woven polyester fibers such as Dacron� fibers (E.I. Du Pont De Nemours & Co., Inc.), and bovine vein crosslinked with glutaraldehyde. One common conduit is a homograft, which is a vessel harvested from a cadaver and treated for implantation into a recipient's body. These conduits may contain a valve at a fixed position within the interior lumen of the conduit that functions as a replacement pulmonary valve. One such conduit 202 comprises a bovine jugular vein with a trileaflet venous valve preserved in buffered glutaraldehyde. Other valves are made of synthetic materials and are attached to the wall of the lumen of the conduit. The conduits may also include materials having a high X-ray attenuation coefficient (radiopaque materials) that are woven into or otherwise attached to the conduit, so that it can be easily located and identified. As shown in FIGS. 2A and 2B, conduit 202, which houses valve 204 within its inner lumen, is installed within a patient by sewing the distal end of conduit 202 to pulmonary artery 110, and, as shown in FIG. 2C, attaching the proximal end of conduit 202 to heart 100 so that the lumen of conduit 202 connects to right ventricle 1 16. Over time, implanted prosthetic conduits and valves are frequently subject to calcification, causing the affected conduit or valve to lose flexibility, become misshapen, and lose the ability to function effectively. Additional problems are encountered when prosthetic valves are implanted in young children. As the child grows, the valve will ultimately be too small to handle the increased volume of blood flowing from the heart to the lungs. In either case, the valve needs to be replaced. The current invention discloses devices and methods for percutaneous catheter based placement of stented valves for regulating blood flow through a pulmonary artery. In a preferred embodiment, the valves are attached to an expandable support structure and they are placed in a valved conduit that is been attached to the pulmonary artery, and that is in fluid communication with the right ventricle of a heart. The support structure can be expanded such that any pre-existing valve in the conduit is not disturbed, or it can be expanded such that any pre-existing valve is pinned between the support structure and the interior wall of the conduit. The delivery catheter carrying the stented valve is passed through the venous system and into a patient's right ventricle. This may be accomplished by inserting the delivery catheter into either the jugular vein or the subclavian vein and passing it through superior vena cava into right atrium. The catheter is then passed through the tricuspid valve, into right ventricle, and out of the ventricle into the conduit. Alternatively, the catheter may be inserted into the femoral vein and passed through the common iliac vein and the inferior vena cava into the right atrium, then through the tricuspid valve, into the right ventricle and out into the conduit. The catheters used for the procedures described herein may include radiopaque markers as are known in the art, and the procedure may be visualized using fluoroscopy, echocardiography, ultrasound, or other suitable means of visualization. The current invention discloses devices and methods for percutaneous catheter based placement of stented valves such as stented valve 306, shown in FIG. 3A, for regulating blood flow through a pulmonary artery. In a preferred embodiment, shown in FIG. 3A, the valve, such as valve 302, is attached to an expandable support structure 304. The stented valve is placed in a valved conduit that has been attached to pulmonary artery 122, and that is in fluid communication with right ventricle 116 of heart 100. Support structure 304 can be expanded such that any pre-existing valve in the conduit is not disturbed, or it can be expanded such that any pre-existing valve is pinned between the support structure and the interior wall of the conduit. One embodiment of a stented valve suitable for use in the present invention is disclosed in U.S. Pat. No. 5,957,949 titled “Percutaneous Placement Valve Stent” to Leonhardt, et al., which is assigned to the same assignee as the present application. The contents of the '949 Patent are hereby incorporated by reference. After a conduit has been implanted, it may become calcified or stretch over time. This stretching or calcification can result in a treatment site that is not round and symmetrical. This often results in an inadequate seal between the exterior surface of stented valve 306 and the wall of the conduit or vessel. One embodiment of the invention is stented valve 310, shown in FIG. 3B, in which the exterior surface of stented valve 306 has been covered with a flexible barrier material 308, shown in FIG. 3C. In one embodiment, barrier material 308 comprises directionally oriented microfibers attached to the surface of stented valve 310 and extending outward. The microfibers comprise biostable materials such as carbon, silica, polyester, nylon, polyamides, polyolefins, polyurethanes and combinations of these and other materials. In one embodiment of the invention, the microfibers are attached to a thin, pliable film or fabric that forms a covering layer over the exterior of stent portion 304 of replacement valve 310. The film comprises polyamide, polyurethane, polyimide, polytetrafluroethylene (PTFE), fluorinated ethylene propylene, a fabric of woven polyester fibers such as Dacron� fibers (E.I. Du Pont De Nemours & Co., Inc.), or other medically acceptable polymers. The microfibers are attached to the film by bonding or with an adhesive. In one embodiment, the microfibers are formed integrally with the film or fabric. When stented valve 310 is positioned at the treatment site within the lumen of conduit 202 or a vessel, the directionally oriented microfibers extend outward and contact the interior wall of the conduit and form a barrier that prevents blood from flowing around stented valve 310, between the outer surface of the stented valve and the inner wall of the conduit. The microfibers also press against the interior surface of the wall of conduit 202 and exert a small but significant force that is sufficient to prevent stented valve 310 from migrating along the length of conduit 202. In another embodiment of the invention, barrier member 308 is a foam matrix that is readily compressible. The foam matrix comprises one or more materials such as open cell sponge, polyurethane foam, collagen polyvinyl alcohol, and poly(2-hydroxyethyl methacrylate). In one embodiment of the invention, the foam is compressed in the dry state, and expands as it absorbs water or bodily fluids. Stented valve 310 covered with a compressible foam barrier is delivered to the treatment site in the dry compressed state, and when it is positioned in the lumen of conduit 202 within the vascular system and exposed to blood or other aqueous bodily fluids, the foam absorbs fluid, expands, and fills the space between stented valve 310 and the interior wall of conduit 202 thus forming a barrier that prevents blood flow around valve 310 between the outer surface of the stented valve and the inner wall of the conduit. The expanded foam exerts sufficient force on the wall to maintain stented valve 310 in a fixed position at the treatment site. In another embodiment of the invention, the barrier member comprises polyester batting adhered to the exterior surface of stented valve 310. Polyester batting is a disordered array of polyester microfibers that forms a soft, compressible mass. When stented valve 310 is positioned within the lumen of conduit 202, the polyester batting expands and presses against the wall of conduit 202 and forms a barrier to blood flow around valve 310. In addition, the polyester batting exerts sufficient force on the wall of conduit 202 to prevent stented valve 310 from migrating along the conduit. In one embodiment of the invention, the barrier material is not attached to the exterior of stented valve 310, but instead, is deployed from the delivery catheter and positioned around the exterior surface of a valve such as stented valve 306 after stented valve 306 has been positioned at the treatment site in the lumen of conduit 202, (FIG. 4). In this embodiment, the barrier comprises, for example, flexible helical coil 406 made of one or more medically acceptable materials. Appropriate materials include, but not limited to, platinum, nitinol, platinum-iridium alloy, other platinum alloys, polyvinyl acid, polyvinyl pyrolidone and collagen. The helical coils may be of varying length and diameters, and may include radiopaque markers to facilitate accurate placement of helical barrier material 406. As shown in FIG. 4, to deploy helical barrier material 406 from delivery catheter 404, the distal tip of catheter 404 is placed adjacent to the space between stented valve 306 and the surface of inner wall 206 of conduit 202. Helical barrier material 406 is delivered from the distal tip of catheter 404 and injected between exterior surface 304 of stented valve 306 and the interior surface of conduit 202. Helical barrier material 406 forms a cage-like, open structure that fills the space between stented valve 306 and the surface of the interior wall of conduit 202. Blood flow through the cage-like structure formed by helical barrier material 406 is slowed, and a blood clot forms that fills the intervening space and provides a barrier to further blood flow. In addition, the framework provided by helical barrier material 406 has sufficient mechanical strength to support stented valve 306 and prevent it from moving out of position at the target site. FIG. 5 is a schematic view of a stented valve 310 or 306 positioned at the treatment site within the lumen of conduit 202 with a barrier disposed about the exterior surface of the valve device. The barrier may be a barrier member such as barrier material 308 that is attached to exterior surface 304 of stented valve 310, or, as in the case of the helical coil barrier, it may be positioned around valve device 306 after valve device 306 is situated at the treatment site. In either case, if the lumen of conduit 202 is not symmetrical and precisely complementary to the exterior surface of the valve device, barrier material 308 or 406 fills the space between the exterior surface of valve device 306 or 310 and the wall 206 of conduit 202. The barrier material prevents blood flow around the exterior surface of implanted valve 306 or 310 and prevents the valve device from moving from a fixed location at the treatment site and migrating along the length of conduit 202. FIG. 6 is a flowchart illustrating method 600 for treating right ventricular outflow tract abnormalities by replacing a pulmonary valve in a nonsymmetrical region of a conduit, and using a barrier to prevent blood flow around the periphery of the replacement valve, in accordance with the present invention. Beginning at Block 602, a stented valve such as valve 306 or 310 is mounted on a delivery catheter such as catheter 404. The distal portion of delivery catheter 404 is then passed through the venous system and into a patient's right ventricle 1 16. This may be accomplished by inserting delivery catheter 404 into either the jugular vein or the subclavian vein, and passing it through the superior vena cava into right atrium 118. The catheter is then passed through tricuspid valve 104, into right ventricle 116, and out of the ventricle into conduit 202. Alternatively, delivery catheter 404 may be inserted into the femoral vein and passed through the common iliac vein and the inferior vena cava into right atrium 118, then through tricuspid valve 104, into right ventricle 116, and out into conduit 308. The catheters used for the procedures described herein may include radiopaque markers as is known in the art, and the procedure may be visualized using fluoroscopy, echocardiography, ultrasound, or other suitable means of visualization. Next, stented valve device 306 or 310 is deployed from catheter 404 (Block 604), and positioned at the treatment site within conduit 202 (Block 606). As indicated in Block 608, a barrier is then formed around the exterior surface of either stented valve device 306 or 310. In the case of stented valve device 310, barrier member 308 is attached to, and disposed about, at least a portion of the exterior surface of stented valve 310. Barrier member 308, for example directionally oriented microfibers or a layer of compressible foam, contacts the interior wall of conduit 202 and forms a barrier to blood flow. In one embodiment of the invention, barrier member 308 is a compressible foam that absorbs bodily fluid and expands and forms a barrier by filling the space between stented valve 310 and the interior wall of conduit 202. In one embodiment, stented valve device 306 is positioned within conduit 202, and a flexible coil barrier material 406 is injected between the exterior of stented valve device 306 and the wall of conduit 202. Blood trapped within the matrix formed by helical coil material 406 clots and forms a barrier to blood flow. In any of the above embodiments, the barrier around the exterior of stented valve device 306 or 310 prevents blood flow around the exterior surface of stented valve device 306 or 310, and maintains stented valve 306 or 310 in a fixed position, by preventing the valve device from migrating along the length of the conduit as indicated in Block 614. While the invention has been described with reference to particular embodiments, it will be understood by one skilled in the art that variations and modifications may be made in form and detail without departing from the spirit and scope of the invention. Referenced byCiting PatentFiling datePublication dateApplicantTitleUS7780726Aug 24, 2010Medtronic, Inc.Assembly for placing a prosthetic valve in a duct in the bodyUS7892281Feb 22, 2011Medtronic Corevalve LlcProsthetic valve for transluminal deliveryUS8002826Oct 14, 2009Aug 23, 2011Medtronic Corevalve LlcAssembly for placing a prosthetic valve in a duct in the bodyUS8241274Aug 14, 2012Medtronic, Inc.Method for guiding a medical deviceUS8540768Dec 30, 2011Sep 24, 2013Sorin Group Italia S.R.L.Cardiac valve prosthesisUS8579966Feb 4, 2004Nov 12, 2013Medtronic Corevalve LlcProsthetic valve for transluminal deliveryUS8603159Dec 11, 2009Dec 10, 2013Medtronic Corevalve, LlcProsthetic valve for transluminal deliveryUS8628570Aug 18, 2011Jan 14, 2014Medtronic Corevalve LlcAssembly for placing a prosthetic valve in a duct in the bodyUS8721708Sep 23, 2011May 13, 2014Medtronic Corevalve LlcProsthetic valve for transluminal deliveryUS8920492Aug 21, 2013Dec 30, 2014Sorin Group Italia S.R.L.Cardiac valve prosthesisUS8986329Oct 28, 2013Mar 24, 2015Medtronic Corevalve LlcMethods for transluminal delivery of prosthetic valvesUS8998979Feb 11, 2014Apr 7, 2015Medtronic Corevalve LlcTranscatheter heart valvesUS8998981Sep 15, 2009Apr 7, 2015Medtronic, Inc.Prosthetic heart valve having identifiers for aiding in radiographic positioningUS9060856Feb 11, 2014Jun 23, 2015Medtronic Corevalve LlcTranscatheter heart valvesUS9060857Jun 19, 2012Jun 23, 2015Medtronic Corevalve LlcHeart valve prosthesis and methods of manufacture and useUS9066799Jan 20, 2011Jun 30, 2015Medtronic Corevalve LlcProsthetic valve for transluminal deliveryUS20120271398 *Sep 10, 2010Oct 25, 2012Symetis SaAortic bioprosthesis and systems for delivery thereofUSD732666Aug 9, 2011Jun 23, 2015Medtronic Corevalve, Inc.Heart valve prosthesis* Cited by examinerClassifications U.S. Classification623/1.26, 623/2.11, 623/2.38International ClassificationA61F2/06, A61F2/24Cooperative ClassificationA61F2/2427, A61F2/06, A61F2250/0069, A61L27/303, A61F2/2418, A61L27/34, A61F2002/077, A61F2/2475, A61F2/2412, A61F2210/0061European ClassificationA61F2/24H, A61L27/34, A61L27/30A, A61F2/24DLegal EventsDateCodeEventDescriptionApr 6, 2006ASAssignmentOwner name: MEDTRONIC VASCULAR, INC., CALIFORNIAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BIRDSALL, MATTHEW;REEL/FRAME:017432/0713Effective date: 20060406Nov 10, 2009CCCertificate of correctionOct 29, 2012FPAYFee paymentYear of fee payment: 4RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services